KR19980082053A - Structure of cervical cancer screening brush - Google Patents
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- KR19980082053A KR19980082053A KR1019980033549A KR19980033549A KR19980082053A KR 19980082053 A KR19980082053 A KR 19980082053A KR 1019980033549 A KR1019980033549 A KR 1019980033549A KR 19980033549 A KR19980033549 A KR 19980033549A KR 19980082053 A KR19980082053 A KR 19980082053A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0291—Instruments for taking cell samples or for biopsy for uterus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4318—Evaluation of the lower reproductive system
- A61B5/4331—Evaluation of the lower reproductive system of the cervix
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6875—Uterus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B2010/0216—Sampling brushes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B2010/0225—Instruments for taking cell samples or for biopsy for taking multiple samples
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B2017/320004—Surgical cutting instruments abrasive
- A61B2017/320012—Brushes
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Abstract
본 발명은 자궁경부암검진용브러쉬의 구조에 관한 것으로,부인병의 수위를 차지하고 있는 자궁경부암은 선별검진이 매우 효과적인데 지난 수십년간 자궁경부 세포진 검사는 가장효율적이며,경제적인 자궁경부암 선별검진법으로 받아 들여져 왔었지만,국내의 경우 매년 6,000여명의 환자들이 새로 발생한다는 것은 자궁경부암의 선별검진법에 문제가 있음을 암시하고 있다.(보사부 1993) 즉,자궁경부는 내경부(endocervix)와 외경부(exocervix )로 나뉘는데,자궁경부암은 주로 외경부와 내경부가 만나는 부위에 잘 발생되는데 비해 위와 같은 기존의 자궁경부암 검사기구들은 내경부와 외경부를 따로따로 검사하여야하는 어려움 때문에 번거로운 것은 물론이며 진단도 정확하지 못하였다. 이에 본 발명은 길이 1.2㎝의 스쿠루와이어(3;Screw Wire)에 직경 5㎜의 브러쉬부(1)를 손잡이(2)자루에 길이방향으로 삽입 형성하되,길이 2㎝의 스쿠루와이어(3;Screw Wire)에 직경 5㎜의 측방 브러쉬부(1')를 일측, 또는 양측으로 상기 브러쉬부(1)에 일체로 형성한 모델 L형과 T 형으로 제작한 브러쉬에 의해 단한번의 조작으로 내경부세포와 외경부의 세포를 동시에 채취할수 있어,내외경부의 병변들을 슬라이드(400)의 양측면으로 분리해 검사한후 외경부세포와 내경부 세포를 별도로 판독할수 있으므로 병변의 위치를 명확히 알수 있어 자궁경부암검진의 위음성율을 낮출수 있는 효과가 있었다.The present invention relates to the structure of the cervical cancer screening brush, cervical cancer occupying the level of women's disease is very effective screening screening cervical Pap smear has been accepted as the most efficient and economical cervical cancer screening method in the past decades In Korea, the incidence of 6,000 new cases every year suggests a problem with screening methods for cervical cancer (Ministry of Health, 1993), which means that the cervix is endocervix and exocervix. Cervical cancer is most likely to occur in the areas where the neck and neck meet, whereas the conventional cervical cancer screening devices are cumbersome due to the difficulty of examining the neck and the neck separately. It was. Thus, the present invention is inserted into the handle (2) in the lengthwise direction of the brush portion (1) of 5mm diameter on the screw wire (3; Screw Wire) of 1.2cm in length, but the length of the 2cm Sukuru wire (3) The brush made of model L type and T type in which the side brush portion 1 'having a diameter of 5 mm on one side or both sides is integrally formed on the brush portion 1 on the screw wire. Inner and outer neck cells can be collected at the same time, and the lesions of the inner and outer necks can be separated and examined on both sides of the slide 400, and then the outer neck and inner neck cells can be read separately so that the position of the lesion can be clearly identified. It was effective to lower false negative rate of cervical cancer screening.
Description
본 발명은 자궁경부암검진용브러쉬의 구조에 관한 것이다.부인병의 수위를 차지하고 있는 자궁경부암은 국가의 후진성을 대변하기도 하며 많은 사회,경제적 손실을 초래하여 그 대책이 시급히 요청되고 있는 실정이다.이러한 자궁경부암의 감소를 위해서는 선별검진이 매우 효과적인데 지난 수십년간 자궁경부 세포진 검사는 가장효율적이며,경제적인 자궁경부암 선별검진법으로 받아 들여져 왔었다.The present invention relates to the structure of the cervical cancer screening brush. Cervical cancer, which occupies the level of gynecological diseases, represents the backwardness of the state and causes many socio-economic losses, and the situation is urgently required. Screening tests are very effective for reducing cervical cancer. Cervical cytology has been accepted as the most efficient and economical screening method for cervical cancer for decades.
이 검사법은 1928년 파팬니콜라우(Papanicolaou)에 의해 개발된후 북미,유럽 각국에서는 국자적 차원에서 집단검진법으로 사용하였고,이로인해 자궁 경부암의 유병률과 사망율의 급격한 감소를 가져 왔으며,현재는 자궁 경부암의 가장 현실적이고 간편한 검진법으로 자리잡고 있는 실정이다.(Koss, 1989;Richart,1959;Burns et al.,1969)This test was developed by Papanicolaou in 1928 and used as a group screening method at the national level in North America and Europe. This resulted in a sharp decrease in the prevalence and mortality of cervical cancer. It is one of the most realistic and convenient screening methods for cervical cancer (Koss, 1989; Richart, 1959; Burns et al., 1969).
본 발명은 이와같은 지난 수십년동안 자궁경부암 검진법에 의해서도,국내의 경우 매년 6,000여명의 환자들이 새로 발생한다는 것은 자궁경부암의 선별검진법에 문제가 있음을 암시하고 있다.(보사부 1993)The present invention suggests that there is a problem in the screening method of cervical cancer, which occurs in Korea in the last few decades by the cervical cancer screening method.
특히 100%의 집단 검진율을 보인 캐나다의 브리스 컴롬비아주(British columbia)에서조차 자궁경부암은 여전히 발생되고 있는데,이는 6∼55%에 달하는 자궁경부 세포진 검사의 높은 위음성율에 기인하고 있는 것으로 보고 되고 있다.(Soost et al.,1991; Sherman et al.,1994; Orr ＆ Shingleton et al.,1995; Coppelson ＆ Brown,1974;Fetherson,1983; Maggi et al.,1989).Cervical cancer still occurs, even in Bris- columbia, Canada, where the population screening rate is 100%, which is reported to be due to the high false negative rate of cervical Pap smears of 6-55%. (Soost et al., 1991; Sherman et al., 1994; Orr & Shingleton et al., 1995; Coppelson & Brown, 1974; Fetherson, 1983; Maggi et al., 1989).
이렇듯 자궁경부암 선별검진을 위한 세포진 검사가 높은 위음성율을 가지는 것은 검체의 채취방법에서의 문제를 주된 원인으로 들수 있는데,이를 극복하기 위한 많은 모델이 제시되고 있으나 뚜렷한 해결책이 없는 것이 현실이다.As such, the high false negative rate of cytology for screening for cervical cancer may be the main cause of the problem in the sampling method. However, many models have been proposed to overcome this problem, but there is no clear solution.
즉,자궁경부는 내경부(endocervix)와 외경부(exocervix )로 나뉘는데,자궁경부암은 주로 외경부와 내경부가 만나는 부위에 잘 발생되는데 비해 기존의 자궁경부암 검사기구들은 내경부와 외경부를 따로따로 검사하여야하는 어려움 때문에 번거로운 것은 물론이며 진단도 정확하지 못하였다.In other words, the cervix is divided into endocervix and exocervix. Cervical cancer occurs mainly at the site where the external and internal neck meet, whereas conventional cervical cancer screening apparatuses should be examined separately for the internal and external cervical areas. Of course, the difficulty was difficult, and the diagnosis was not accurate.
자궁경부암 검사는 자궁경부로부터 병반세포를 채취하기 위한 여러 기구에는 몇가지 종류가 있으나,자궁경부 전체로부터 세포를 얻기에는 미흡한 점이 많다.현재 많이 사용하고 있는 종류는 스웨덴의 메드스칸(MEDSCAND)사의 특허에 의한 I자형 브러쉬인데,이는 도 1내지 도 4에 도시된바와 같이,길이 15㎝,직경 2.5㎜의 연질 플라스틱제 손잡이(2) 자루에 길이 2㎝의 스쿠루와이어(3;Screw Wire)에 직경 5㎜의 브러쉬부(1)가 형성되어진 I형 브러쉬(100)로서,이는 단지 자궁 내경부(7)에 적합한 것으로서,정작 자궁경부암의 발생은 외경부(6)에서 자주 발생함에도 불구하고,내경부(7)에만 적합한 구조여서 주요 병변을 간과하는 경우가 많아 오진율이 높았던 것이다.상기와 같은 점을 감안한 본 발명에서는 단 한번의 간단한 조작에 의해서도 자궁내경부(7)와 외경부(6)의 병변세포를 동시에 채취할 수 있도록 하여 기존I형 브러쉬의 높은 위음성율을 개선하는데 있다.There are several types of cervical cancer screening tools for collecting diseased cells from the cervix, but they are inadequate for obtaining cells from the entire cervix. Currently, many types of cervical cancer are used in Swedish patents of MEDSCAND. It is an I-shaped brush, which is as shown in Figs. 1 to 4, which has a diameter of 15 cm in length and 2.5 mm in diameter of a soft plastic handle 2 having a length of 2 cm in a screw wire. An I-shaped brush 100 having a 5 mm brush portion 1 formed therein, which is only suitable for the internal cervix 7, although the occurrence of cervical cancer frequently occurs in the outer cervix 6, Since the structure is suitable only for the cervix 7, the major lesions are often overlooked, and thus the false positive rate is high. In the present invention in view of the above, the uterine cervix 7 and the outer cervix 6 can be obtained by a simple operation. By making sure that the lesion cells collected at the same time to improve the high false negative rate of the conventional I-form brush.
도 1은 종전 사용되던 I형 브러쉬 사시도,1 is a perspective view of a type I brush that was used in the past,
도 2는 종전 사용되던 I형 브러쉬의 종단면도,Figure 2 is a longitudinal cross-sectional view of a type I brush used in the past,
도 3은 종전 사용되던 I형 브러쉬로 내경부만의 병변 검진상태 참고도,3 is a reference diagram of the lesion examination state of the internal diameter only with the type I brush that was used before,
도 4는 종전 사용되던 I형 브러쉬로 검진한 병변을 슬라이드에 옮긴 사용상태참고도,Figure 4 is a reference state used to move the lesion on the slide screened with the type I brush used previously,
도 5는 본 발명에 따른 브러쉬의 사시도로서,(i)은 L형,(ii)는 T형 브러쉬.5 is a perspective view of a brush according to the present invention, (i) L-type, (ii) T-type brush.
도 6은 본 발명에 따른 브러쉬로 자궁의 내,외경부의 병변 동시 검진상태 참고도로서,(i)은 L형 브러쉬의 일실시참고도, (ii)는 T형 브러쉬의 일실시 참고도,Figure 6 is a reference of the examination of the lesion at the same time the internal and external cervical lesions of the uterus with the brush according to the present invention, (i) one embodiment reference of the L-type brush, (ii) one embodiment reference of the T-type brush,
도 7은 본 발명에 따른 브러쉬로 검진한 병변을 슬라이드의 좌편에는 외경부의 병변을 우편에는 내경부의 병변을 옮긴 사용상태 참고도로서,(i)은 L형 브러쉬의 일실시 참고도, (ii)는 T형 브러쉬의 일실시 참고도.7 is a reference diagram showing the use of the lesions examined by the brush according to the present invention, the lesion of the outer diameter portion on the left side of the slide and the lesion of the inner diameter portion on the mail, (i) is one embodiment reference of the L-shaped brush, (ii ) Is also one embodiment reference of the T-shaped brush.
※도면의 주요부분에 대한 부호의 설명※ Explanation of symbols for main parts of drawing
100:I형 브러쉬 200:L형 브러쉬100: I type brush 200: L type brush
300:T형 브러쉬 400:슬라이드300: T type brush 400: Slide
1:브러쉬부 1':측방브러쉬부1: Brush part 1 ': Side brush part
2:손잡이 3:스쿠루와이어(SCREW WIRE)2: Handle 3: Scrub wire (SCREW WIRE)
4:내경부병변 5:외경부병변4: internal neck lesion 5: external neck lesion
6:외경부(exocervix ) 7:내경부(endocervix)6: exocervix 7: endocervix
길이 15㎝,직경 2.5㎜의 연질 플라스틱제 손잡이(2) 자루에 브러쉬부(1)를 형성함에 있어서, 길이 1.2㎝의 스쿠루와이어(3;Screw Wire)에 직경 5㎜의 브러쉬부(1)를 손잡이(2)자루에 길이방향으로 삽입 형성하되,길이 2㎝의 스쿠루와이어(3;Screw Wire)에 직경 5㎜의 측방 브러쉬부(1')를 일측 ,또는 양측으로 상기 브러쉬부(1)에 일체 구조로 형성되어진 것이다.In forming the brush part 1 in the handle of the soft plastic handle 2 made of 15 cm in length and 2.5 mm in diameter, the brush part 1 having a diameter of 5 mm in a screw wire 3 in length of 1.2 cm is formed. Insert the handle (2) into the lengthwise direction, but the side brush portion (1 ') having a diameter of 5 mm on one side or both sides of the brush wire (2; length of 2cm screw wire) It is formed in a unitary structure.
이와 같이 구성된 본 발명의 작용으로는 도 5에 도시된바와 같이 측방브러쉬부(1')가 일측,또는 양측방으로 형성된 자궁경부암검진용브러쉬는 도 6은 본 발명에 따른 브러쉬로 자궁의 내,외경부의 병변 동시 검진상태 참고도로서,(i)은 L형 브러쉬의 일실시참고도, (ii)는 T형 브러쉬의 일실시 참고도에 기재된바와 같이 종전과 같이 자궁의 내경부(7)의 병변을 채취함과 동시에,내경부(7)의 외방으로 융설확관된 외경부(6) 부위의 병변까지 동시에 접촉시켜,손잡이(2)를 시계방향,또는 반시계방향으로 돌려 자궁의 내경부(7)와 외경부(6)의 병변을 채취하는데 유용하게 작용하는 것이다.As the action of the present invention configured as described above, as shown in FIG. 5, the side brush portion 1 'is formed on one side or both sides of the cervical cancer screening brush of FIG. 6 is a brush according to the present invention. Simultaneous examination of the lesions of the outer neck, as shown in (i) of one embodiment of the L-shaped brush, and (ii) of one embodiment of the T-shaped brush, At the same time as the lesion is collected, the lesion is contacted to the lesion of the outer diameter portion 6 that is fusion-expanded to the outside of the inner diameter portion 7, and the handle 2 is turned clockwise or counterclockwise to rotate the inner diameter portion of the uterus ( 7) and to extract the lesions of the outer diameter (6) will be useful.
이와 같이 자궁암검진을 위한 내,외경부(7;6)의 병변을 동시에 채취될수 있게된 본 발명 브러쉬의 일실시 작용효과로는 다음과 같다.Thus, the effect of one embodiment of the brush of the present invention that can be collected at the same time the lesion of the inner, outer neck (7; 6) for uterine cancer screening as follows.
본 발명에 따른 L형 또는 T형으로된 브러쉬로 단한번의 조작으로 내경부세포와 외경부의 세포를 동시에 채취한 자궁 내,외경부 병변은 도 7에 도시된바와 같이 슬라이드(400)의 좌편에는 외경부의 병변(5)을 우편에는 내경부의 병변(4)을 슬라이드(400)의 양측면으로 분리해 검사한후 외경부세포와 내경부 세포를 별도로 판독할수 있으므로 병변의 위치를 명확히 알수 있다.Intrauterine and external cervical lesions, which are simultaneously collected by the internal cervical cells and the external cervical cells in a single operation with a brush of L or T type according to the present invention, are shown on the left side of the slide 400 as shown in FIG. In the post-mortem lesion 5, the inner cervix lesion 4 is separated from both sides of the slide 400, and the outer cervical cells and the inner cervical cells can be read separately so that the position of the lesion can be clearly understood.
또한 기존에 제시되고 있는 브러쉬 모델(I형)과 비교할 때 제작단가도 낮고,길이 2㎝의 스쿠루와이어(3;Screw Wire)에 직경 5㎜의 측방 브러쉬부(1')를 일측, 또는 양측으로 상기 브러쉬부(1)에 일체 구조로 형성해 손잡이(2)에 일체 삽입고정시키는것과 같이,제작과정도 복잡하지 않아 쉽게 보급하여 국내 및 전세계적으로 자궁경부암의 발병율을 낮추는데 크게 기여 하리라 생각된다.In addition, compared to the existing brush model (type I), the manufacturing cost is lower, and the side brush portion 1 'having a diameter of 5 mm on one side or both sides of the screw wire having a length of 2 cm is included. By forming an integral structure in the brush part 1 and inserting and fixing it integrally in the handle 2, the manufacturing process is not complicated, and thus, it can be easily distributed and greatly contribute to lowering the incidence of cervical cancer in Korea and worldwide.
현재에도 본인이 재직하는 대학병원에서 임의로 제작해 임상에 시도중인바,1회의 검진으로 내,외경부의 세포를 채취 검진할수 있는 편리성은 물론 정확도에 있어서,기존의 브러쉬의 높은 위음성율을 개선하는데 현저한 효과가 있는 유용한 발명인 것이다.At present, I am trying to make a clinical trial at the university hospital where I work, and it is remarkable to improve the false negative rate of the existing brushes in terms of convenience and accuracy in collecting and inspecting the cells of the inner and outer neck with one examination. It is a useful invention that works.
Claims (1)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019980033549A KR19980082053A (en) | 1998-08-17 | 1998-08-17 | Structure of cervical cancer screening brush |
| PCT/KR1999/000433 WO2000009984A2 (en) | 1998-08-17 | 1999-08-05 | Structure of brush for examining uterine cervical cancer |
| AU50699/99A AU5069999A (en) | 1998-08-17 | 1999-08-05 | Structure of brush for examining uterine cervical cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019980033549A KR19980082053A (en) | 1998-08-17 | 1998-08-17 | Structure of cervical cancer screening brush |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR19980082053A true KR19980082053A (en) | 1998-11-25 |
Family
ID=19547598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019980033549A KR19980082053A (en) | 1998-08-17 | 1998-08-17 | Structure of cervical cancer screening brush |
Country Status (3)
| Country | Link |
|---|---|
| KR (1) | KR19980082053A (en) |
| AU (1) | AU5069999A (en) |
| WO (1) | WO2000009984A2 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20030643A1 (en) | 2003-04-01 | 2004-10-02 | Copan Innovation Ltd | BUFFER FOR THE COLLECTION OF BIOLOGICAL SAMPLES |
| IT1401447B1 (en) | 2010-06-09 | 2013-07-26 | Copan Italia Spa | METHOD FOR THE QUANTITATIVE TRANSFER OF ANALYTES |
| IT1403618B1 (en) | 2011-01-05 | 2013-10-31 | Copan Italia Spa | PROCEDURE FOR REALIZING A DEVICE FOR THE COLLECTION AND TRANSFER OF SAMPLES FOR MOLECULAR BIOLOGY |
| ITMI20121603A1 (en) | 2012-09-25 | 2014-03-26 | Copan Italia Spa | DEVICE AND METHOD FOR THE COLLECTION AND TRANSFER OF SAMPLES OF BIOLOGICAL MATERIAL |
| CN104981209B (en) | 2012-11-30 | 2018-03-02 | 亿维医药有限公司 | Sample collecting device and external member |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5281980A (en) * | 1975-12-28 | 1977-07-08 | Ouchi Teruo | Brush for diagnosing scratched cells |
| US4227537A (en) * | 1978-03-08 | 1980-10-14 | Tucson Medical Instruments, Inc. | Endometrial brush with slidable protective sleeve |
| US4759376A (en) * | 1984-05-29 | 1988-07-26 | Nils Stormby | Endocervical sampling brush and smear method |
| GB2208603A (en) * | 1987-07-03 | 1989-04-12 | Richards Dr Peter William | Cervical sampling device |
| DE4005266A1 (en) * | 1990-02-20 | 1991-08-22 | Geka Brush Georg Karl Gmbh | Scraper head for collecting cytological smears - has foamed polymer elements forming bristles or bladed surface |
| US5713369A (en) * | 1995-09-13 | 1998-02-03 | Vance Products Inc. | Uterine endometrial tissue sample brush |
-
1998
- 1998-08-17 KR KR1019980033549A patent/KR19980082053A/en not_active Application Discontinuation
-
1999
- 1999-08-05 WO PCT/KR1999/000433 patent/WO2000009984A2/en active Application Filing
- 1999-08-05 AU AU50699/99A patent/AU5069999A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000009984A2 (en) | 2000-02-24 |
| AU5069999A (en) | 2000-03-06 |
| WO2000009984A3 (en) | 2000-06-22 |
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