KR102675027B1 - 에페드린 또는 에페드린 염을 포함하는 조성물 및 그의 제조 및 사용 방법 - Google Patents

에페드린 또는 에페드린 염을 포함하는 조성물 및 그의 제조 및 사용 방법 Download PDF

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Publication number
KR102675027B1
KR102675027B1 KR1020217040545A KR20217040545A KR102675027B1 KR 102675027 B1 KR102675027 B1 KR 102675027B1 KR 1020217040545 A KR1020217040545 A KR 1020217040545A KR 20217040545 A KR20217040545 A KR 20217040545A KR 102675027 B1 KR102675027 B1 KR 102675027B1
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months
ephedrine
less
composition
storage
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Korean (ko)
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KR20220009985A (ko
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샤히드 아메드
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넥서스 파마슈티칼스, 인크.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=73230956&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR102675027(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 넥서스 파마슈티칼스, 인크. filed Critical 넥서스 파마슈티칼스, 인크.
Priority to KR1020247019305A priority Critical patent/KR20240096847A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020217040545A 2019-05-16 2020-05-16 에페드린 또는 에페드린 염을 포함하는 조성물 및 그의 제조 및 사용 방법 Active KR102675027B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247019305A KR20240096847A (ko) 2019-05-16 2020-05-16 에페드린 또는 에페드린 염을 포함하는 조성물 및 그의 제조 및 사용 방법

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962849125P 2019-05-16 2019-05-16
US62/849,125 2019-05-16
PCT/US2020/033310 WO2020232424A1 (en) 2019-05-16 2020-05-16 Compositions comprising ephedrine or an ephedrine salt and methods of making and using same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020247019305A Division KR20240096847A (ko) 2019-05-16 2020-05-16 에페드린 또는 에페드린 염을 포함하는 조성물 및 그의 제조 및 사용 방법

Publications (2)

Publication Number Publication Date
KR20220009985A KR20220009985A (ko) 2022-01-25
KR102675027B1 true KR102675027B1 (ko) 2024-06-14

Family

ID=73230956

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020217040545A Active KR102675027B1 (ko) 2019-05-16 2020-05-16 에페드린 또는 에페드린 염을 포함하는 조성물 및 그의 제조 및 사용 방법
KR1020247019305A Pending KR20240096847A (ko) 2019-05-16 2020-05-16 에페드린 또는 에페드린 염을 포함하는 조성물 및 그의 제조 및 사용 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020247019305A Pending KR20240096847A (ko) 2019-05-16 2020-05-16 에페드린 또는 에페드린 염을 포함하는 조성물 및 그의 제조 및 사용 방법

Country Status (10)

Country Link
US (7) US11090278B2 (https=)
EP (1) EP3968975A4 (https=)
JP (3) JP2022532657A (https=)
KR (2) KR102675027B1 (https=)
CN (1) CN113825500A (https=)
AU (1) AU2020276619A1 (https=)
CA (1) CA3140043A1 (https=)
IL (1) IL288044A (https=)
MX (1) MX2021013888A (https=)
WO (1) WO2020232424A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11090278B2 (en) 2019-05-16 2021-08-17 Nexus Pharmaceuticals, Inc. Compositions comprising ephedrine or an ephedrine salt and methods of making and using same
US10869845B1 (en) 2020-01-22 2020-12-22 Nevakar Inc. Ephedrine compositions and methods
US20230172840A1 (en) 2021-12-05 2023-06-08 Fresenius Kabi Austria Gmbh Ephedrine liquid formulations
CN120241601B (zh) * 2025-06-04 2025-08-22 成都苑东生物制药股份有限公司 盐酸麻黄碱注射液及其制剂工艺

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050021092A1 (en) 2003-06-09 2005-01-27 Yun Anthony Joonkyoo Treatment of conditions through modulation of the autonomic nervous system

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK339289D0 (da) * 1989-07-07 1989-07-07 Dak Lab As Farmaceutisk praeparat
FR2890316B1 (fr) 2005-09-02 2007-10-05 Aguettant Soc Par Actions Simp Seringue destinee a etre remplie puis sterilisee par autoclavage a la vapeur.
FR2896168B1 (fr) 2006-01-19 2008-10-17 Aguettant Soc Par Actions Simp Seringue hypodermique preremplie equipee d'un dispositif de bouchage
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
WO2012010238A1 (en) * 2010-07-17 2012-01-26 Merck Patent Gmbh Enhancement of penetration and action
FR2963237B1 (fr) 2010-07-28 2013-05-17 Aguettant Lab Nouvelle composition pharmaceutique utile pour prevenir ou traiter l'hypotension arterielle peroperatoire chez l'etre humain
CN103501775A (zh) * 2011-03-04 2014-01-08 格吕伦塔尔有限公司 他喷他多的胃肠外给药
FR2992222B1 (fr) 2012-06-22 2015-06-19 Aguettant Lab Dispositif de protection destine a equiper un dispositif d’injection pourvu d’un embout de raccordement
CA2947795A1 (en) * 2014-05-19 2015-11-26 Medicom Innovation Partner A/S A medical cartridge comprising a one way valve
EP2990031B1 (en) 2014-08-28 2019-11-13 Sun Pharmaceutical Industries Ltd Parenteral dosage form of norepinephrine
FR3053893B1 (fr) 2016-07-13 2018-07-27 Laboratoire Aguettant Dispositif medical comportant un emballage et une seringue pre-remplie disposee dans l’emballage
WO2018140894A1 (en) * 2017-01-30 2018-08-02 Nevakar, Inc Norepinephrine compositions and methods therefor
WO2019177725A1 (en) 2018-03-13 2019-09-19 Nevakar Inc. Prefilled syringe, compositions and methods
FR3084263B1 (fr) 2018-07-27 2020-07-10 Laboratoire Aguettant Systeme d’administration comportant un dispositif d’administration et un dispositif de protection pourvu d’une membrane de fermeture
US11090278B2 (en) 2019-05-16 2021-08-17 Nexus Pharmaceuticals, Inc. Compositions comprising ephedrine or an ephedrine salt and methods of making and using same
US10869845B1 (en) 2020-01-22 2020-12-22 Nevakar Inc. Ephedrine compositions and methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050021092A1 (en) 2003-06-09 2005-01-27 Yun Anthony Joonkyoo Treatment of conditions through modulation of the autonomic nervous system

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"Akovaz (ephedrine sulfate injection, USP) for intravenous use-FULL PRESCRIBING INFORMATION", pp.1-8(2016.04.30.), URL: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/208289s000lbl.pdf 1부.*
The European Journal of Hospital Pharmacy Science, 11(5), p.107-110(2005.) 1부.*

Also Published As

Publication number Publication date
JP2025071269A (ja) 2025-05-02
US20220257539A1 (en) 2022-08-18
US11426369B2 (en) 2022-08-30
US11241400B2 (en) 2022-02-08
US11464752B2 (en) 2022-10-11
EP3968975A1 (en) 2022-03-23
JP2023091072A (ja) 2023-06-29
EP3968975A4 (en) 2023-02-15
WO2020232424A1 (en) 2020-11-19
IL288044A (en) 2022-01-01
JP2022532657A (ja) 2022-07-15
US20210353561A1 (en) 2021-11-18
CN113825500A (zh) 2021-12-21
AU2020276619A1 (en) 2021-12-16
US11090278B2 (en) 2021-08-17
MX2021013888A (es) 2022-01-24
US20220265580A2 (en) 2022-08-25
US20210393552A1 (en) 2021-12-23
US20220110892A1 (en) 2022-04-14
KR20220009985A (ko) 2022-01-25
US11478436B2 (en) 2022-10-25
US20200360309A1 (en) 2020-11-19
US20230068187A1 (en) 2023-03-02
CA3140043A1 (en) 2020-11-19
US20230025407A1 (en) 2023-01-26
US11571398B1 (en) 2023-02-07
KR20240096847A (ko) 2024-06-26

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