KR102660898B1 - Graft stents with different lengths of annular members in preparation for curvature of blood vessels - Google Patents

Abstract

The present invention relates to an artificial blood vessel that is installed at the damaged area to allow the blood vessel to function normally when the blood vessel is damaged. It is made of an annular member 200 with a wave shape disposed along the circumferential surface of the outer shell 100 to maintain the shape, and the annular member 200 is a wire with a wave wave and rotates once. While forming a plurality of peak portions (P) and valley portions (V), the annular member 200 or the artificial blood vessel shell 100 is disposed so that the artificial blood vessel is curved, so that it corresponds to the curved portion. An artificial blood vessel stent is provided that varies the cycle of the annular member in preparation for the bending of the blood vessel, which is characterized by having a bending response means.

Description

Artificial blood vessel stents with different lengths of annular members in preparation for curvature of blood vessels}

The present invention relates to an artificial blood vessel stent, and more specifically, to an artificial blood vessel stent that is installed in the damaged area of a blood vessel when the blood vessel is damaged and varies the cycle of the annular member in preparation for the curvature of the blood vessel so that the blood vessel operates normally. .

In general, stenosis of blood vessels may occur due to blood clots or sclerosis, and aneurysms, in which a part of the blood vessel swells like a balloon, may occur due to aging or other diseases.

Conventional methods to treat vascular stenosis or aneurysm include surgical replacement of the blood vessel with an artificial blood vessel, cutting the skin of the lesion to expose the artery to the outside, and then inserting the artificial blood vessel into the inside of the artery using an intubator. It is broadly classified into the incision method for inserting a stent.

According to the incision-type treatment method described above, a stent is inserted into a blood vessel as a way to expand and maintain the passage of a narrowed blood vessel. These stents generally have a cylindrical structure in overall shape and have elasticity themselves. A method that can be contracted by applying an external force and self-expands when the external force is removed is widely used.

In this way, the artificial blood vessel stent that is inserted into the inside of the artery using an inserter is largely an artificial blood vessel body and a stent that has its own elasticity to maintain the shape of the artificial blood vessel body while being inserted into the interior of the artificial blood vessel body. It comes true.

In order to function as a stent, it must have expandability to expand the lumen, flexibility to flexibly adapt while maintaining the curved shape of the lumen at the curved part of the lumen, and shrinkability to shrink to a certain diameter.

In particular, with regard to flexibility among the characteristics of the stent, the conventional stent is composed of an upper cylindrical stent, a middle cylindrical stent, and a lower cylindrical stent that are separated from each other, and the middle cylindrical stent has valley portions and peak portions of the same height formed alternately. It is composed of a plurality of curved wires, and the height and spacing of the valley and peak parts within the intermediate cylindrical stent are formed at a constant level, so it is not suitable for cases where the path to the lesion area of the blood vessel is highly curved, which has the disadvantage of reducing usability.

The reason is that when inserted and installed in a highly curved lesion area, the passage of the lesion area cannot be maintained in its original curved state due to the single-shot force of the stent's cylindrical body trying to return to the straight direction, and returns to a straight (horizontal, vertical) state. As the path returns, the length of the passage in the lesion area increases and the curved area is displaced to a straight line (horizontal, vertical). Additionally, the passage is deformed to be narrower than the original spacing, making it difficult for circulating substances to circulate through this area, making it difficult for the stent to circulate. It has the disadvantage of hindering its original purpose.

Republic of Korea Patent Publication No. 10-2005-0118744 Republic of Korea Patent Publication No. 10-2010-0008394 Republic of Korea Patent Publication No. 10-2011-0090425 Republic of Korea Patent Publication No. 10-2017-0001845

The present invention is intended to solve the above-mentioned problems,

The peak and valley portions of the wave-shaped annular member included in the stent are manufactured with different lengths between adjacent peaks and valley portions, and considering that the artificial blood vessel is arranged to be curved, a bending response means corresponding to the curved portion is provided. The purpose is to provide an artificial blood vessel stent that varies the cycle of the annular member in preparation for the bending of the blood vessel.

However, the object of the present invention is not limited to the objects mentioned above, and other objects not mentioned will be clearly understood by those skilled in the art from the description below.

In order to achieve the above object, the present invention provides an artificial blood vessel that is installed in the damaged area to allow the blood vessel to function normally when the blood vessel is damaged, including an artificial blood vessel shell (100) that functions as a skin for the artificial blood vessel, and the artificial blood vessel shell (100). The vascular sheath 100 is made of an annular member 200 having a wave shape disposed along the circumferential surface of the sheath 100 to maintain its cylindrical shape, and the annular member 200 has a wave wave. As a wire, it rotates once to form a plurality of peak portions and valley portions. Considering that the annular member 200 or the artificial blood vessel shell 100 is arranged to be curved, the artificial blood vessel is disposed to be curved, so that it corresponds to the curved portion. An artificial blood vessel stent is provided to prepare for the bending of blood vessels, which is characterized by having a bending response means.

In addition, the artificial blood vessel outer shell 100 is formed to form a cylindrical shape, and when the cross-section of the cylindrical shape is divided into four equal parts at 0°, 90°, 180°, and 270°, the artificial blood vessel outer sheath 100 has the cylindrical shape. With respect to the longitudinal central axis, the length of the 0° portion parallel to the central axis, the length of the 90° portion, the length of the 180° portion, and the length of the 270° portion are the same, so that the lengths of all portions are unified. , the annular member 200 has a plurality of peak portions and valley portions, the lengths between the plurality of peak portions and adjacent peak portions are formed to be different from each other, and the lengths between the plurality of valley portions and adjacent valley portions are Artificial blood vessel stents are provided to prepare for the curvature of blood vessels, each of which is formed differently.

In addition, the bending response means is arranged so that each annular member 200 is disposed on the artificial blood vessel sheath 100 and has the same length between adjacent peak portions at the same angle with respect to the sheath 100. Preferably, when the angles of the cylindrical cross sections in the shell 100 are different, the lengths between adjacent peaks or valleys of the annular member 200 are also arranged differently, so that when the artificial blood vessel is placed in a curved blood vessel. An artificial blood vessel stent is provided that varies the cycle of the annular member in preparation for the bending of the blood vessel, which allows the artificial blood vessel to be easily bent and disposed.

In addition, when the artificial blood vessel is installed in a curved blood vessel, the artificial blood vessel is bent to match the shape of the curved blood vessel. At this time, the average radius of the innermost part of the bending area in the curved artificial blood vessel is R1. If the average radius of the outermost part of the bent area is R2, the relationship between R1 and R2 is R1 < R2, and the length between adjacent peaks of the annular member 200 at the area where R1 is located is referred to as L1. An artificial blood vessel stent is provided that varies the cycle of the annular member in preparation for the curvature of the blood vessel, wherein the length between adjacent peaks of the annular member 200 gradually increases as it moves from the R1 region to the R2 region. .

In addition, the length between adjacent peak portions of the annular member 200 gradually increases as it moves from the R1 region to the R2 region, and the length is Li (where i = 1, 2, 3,..., n As -1,n), the length between the adjacent peak portions of the annular member 200 at the region where R2 is located is Ln, and the relationship between the sizes of Li is L1<L2<L3<...<Ln-1 An artificial blood vessel stent is provided that varies the cycle of the annular member to prepare for the curvature of the blood vessel, which is characterized by <Ln.

Meanwhile, the artificial blood vessel outer shell 100 is formed to form a cylindrical shape. When the cross-section of the cylindrical shape is divided into four equal parts of 0°, 90°, 180°, and 270°, the artificial blood vessel outer sheath 100 has the cylindrical shape. With respect to the longitudinal central axis, the length K1 of the 0° portion parallel to the central axis, the length K2 of the 90° portion, the length K3 of the 180° portion, and the length K4 of the 270° portion are formed differently from each other, thereby forming the artificial blood vessel. When the outer skin 100 is unfolded to form a cylindrical shape so that the wrinkles are not folded, the artificial blood vessel takes a bent shape, and a plurality of the annular members 200 are installed at regular intervals in the longitudinal direction with respect to the outer skin 100 to form the outer skin ( An artificial blood vessel stent with a different cycle of annular members in preparation for the curvature of blood vessels is provided, which is characterized in that it supports 100).

In addition, the bending response means arranges the annular member 200 in a cylindrical state by unfolding the outer skin 100 so that wrinkles are not folded, and the central axis of the annular member 200 and the central axis of the artificial blood vessel are aligned. When the annular members 200 are arranged to overlap each other, the central axes of each annular member are aligned at equal intervals, and when the artificial blood vessel is installed in a curved blood vessel, the artificial blood vessel It is curved to match the shape of the curved blood vessel.

At this time, if the average radius of the innermost part of the bent area in the curved artificial blood vessel is P1 and the average radius of the outermost part of the bent area is P2, the relationship between P1 and P2 is P1 < P2, and the P1 As the cylindrical cross section of the outer shell 100 of the artificial blood vessel is installed at this location at 0°, the length of the outer sheath 100 of the artificial blood vessel 100 at the portion where P1 is located becomes K1, and from the P1 portion to the P2 portion. An artificial blood vessel stent is provided that varies the cycle of the annular member in preparation for the curvature of the blood vessel, wherein the length of the outer shell 100 gradually increases.

In addition, the length of the sheath 100 gradually increases from the P1 portion to the P2 portion, but the portion where the P2 is located coincides 180° with the cylindrical cross section of the sheath 100, so the length of the artificial blood vessel is K3. The relationship between K1, K2, K3, and K4 is arranged so that K1<K2, K3>K4, and K2=K4, so that when the artificial blood vessel is placed in a curved blood vessel, the length of the outer shell 100 is different. An artificial blood vessel stent is provided that varies the cycle of the annular member in preparation for the bending of the blood vessel, which is characterized in that it can be easily bent and placed.

Meanwhile, a marker 300 is disposed at a predetermined position in each of the annular members 200. The marker 300 is a radio-opaque material that does not transmit radiation, and the marker 300 is in the form of a spring and is attached to the annular member. It is formed by winding a wire of (200) in the longitudinal direction for a predetermined length.

In addition, when the length of one valley part directly connected to one peak part of the wire is M, the predetermined length E around which the marker 300 is wound is M/3 < E < M/2, and the marker 300 is placed on the wire of the annular member so that during the procedure, the position of the marker 300 is placed at the R1 or P1 region, which is the innermost region of the bent region when treating the artificial blood vessel, so that the outermost region of the bent region Characterized in that Ln, which has the longest length between adjacent peaks of the annular member, is placed in the area located at R2 or P2, or K4, which has the longest outer shell of the artificial blood vessel, is placed to easily maintain the bending of the artificial blood vessel. An artificial blood vessel stent is provided that varies the cycle of the annular member in preparation for the curvature of the blood vessel.

In addition, the artificial blood vessel outer shell 100 is made of polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polyurethane (PU), polypropylene (PP), polyethylene, PE), polytetrafluoroethylene (PTFE), polytrimethyleneterephthalate (PTT), polyimide (PI), polyvinylchloride (PVC), polyvinyl alcohol (PVA), Polyvinylpyrrolidone (PVP), polyethyleneglycol (PEG), polysaccharide, polyolefin, nylon, polyether block amide (PEBA, Pebax), carbon fiber, Teflon ) and cotton. An artificial blood vessel stent that varies the cycle of the annular member in preparation for the curvature of the blood vessel is provided, which is made of a material selected from the group consisting of cotton.

The features and advantages of the present invention will become more apparent from the following detailed description based on the accompanying drawings.

Prior to this, terms or words used in this specification and claims should not be interpreted in their usual, dictionary meaning, and the inventor may appropriately define the concept of the term in order to explain his or her invention in the best way. It should be interpreted with meaning and concept consistent with the technical idea of the present invention based on the principle that it is.

As discussed above, according to the present invention, it can be applied to straight or curved blood vessels, and in particular, by improving longitudinal flexibility, when a stent is inserted into a curved blood vessel, it is bent according to the curved shape to form an artificial blood vessel. It has the effect of preventing deformation, eliminating the risk of the connection part with the stent falling off, and preventing movement of the stent when installing it.

1 is a front view schematically showing an artificial blood vessel stent according to an embodiment of the present invention;
Figure 2 is a developed diagram schematically showing an annular member according to an embodiment of the present invention;
Figure 3 is a front view schematically showing the bending state of an artificial blood vessel stent according to an embodiment of the present invention;
Figure 4 is a front view schematically showing the bending state of an artificial blood vessel stent according to another embodiment of the present invention;
Figure 5 is a plan view of an artificial blood vessel stent according to another embodiment of the present invention;
Figure 6 is a front view schematically showing an artificial blood vessel stent according to another embodiment of the present invention;
Figure 7 is a front view schematically showing a state in which a marker is provided on an artificial blood vessel stent according to another embodiment of the present invention;
Figure 8 is an enlarged view of portion "A" in Figure 7.

Hereinafter, preferred embodiments of the present invention will be described with reference to the attached drawings. In this process, the thickness of lines or sizes of components shown in the drawings may be exaggerated for clarity and convenience of explanation.

In addition, the terms described below are terms defined in consideration of functions in the present invention, and may vary depending on the intention or custom of the user or operator. Therefore, definitions of these terms should be made based on the content throughout this specification.

In addition, the examples below do not limit the scope of the present invention, but are merely illustrative of the components presented in the claims of the present invention, and are included in the technical idea throughout the specification of the present invention and constitute the scope of the claims. Embodiments that include elements that can be replaced as equivalents may be included in the scope of the present invention.

The attached Figure 1 is a front view schematically showing an artificial blood vessel stent according to an embodiment of the present invention, Figure 2 is a developed view schematically showing an annular member according to an embodiment of the present invention, and Figure 3 is a schematic illustration of an annular member according to an embodiment of the present invention. A front view schematically showing the bending state of an artificial blood vessel stent according to one embodiment. Figure 4 is a front view schematically showing the bending state of an artificial blood vessel stent according to another embodiment of the present invention. Figure 5 is a plan view of an artificial blood vessel stent according to another embodiment of the present invention, Figure 6 is a front view schematically showing an artificial blood vessel stent according to another embodiment of the present invention, and Figure 7 is a schematic view of an artificial blood vessel stent according to another embodiment of the present invention. FIG. 8 is a front view schematically showing a state in which a marker is provided on an artificial blood vessel stent according to another embodiment of , and FIG. 8 is an enlarged view of portion “A” of FIG. 7 .

As shown in FIG. 1 and below, the artificial blood vessel stent 10 according to the present invention is installed in the damaged area when the blood vessel is damaged so that the blood vessel operates normally.

At this time, the stent 10 has an artificial blood vessel shell 100 that functions as a skin for the artificial blood vessel, and is disposed along the circumferential surface of the shell 100 so that the artificial blood vessel shell 100 maintains its cylindrical shape. It consists of an annular member 200 having a wave shape.

In addition, the annular member 200 is a wire having a wave wave and forms a plurality of peak portions (P) and valley portions (V) while rotating once, and the annular member 200 or the artificial Considering that the artificial blood vessel is arranged to be curved, the blood vessel envelope 100 is provided with bending response means corresponding to the curved portion.

In addition, the artificial blood vessel outer shell 100 is formed to form a cylindrical shape, and when the cross-section of the cylindrical shape is divided into four equal parts at 0°, 90°, 180°, and 270°, the artificial blood vessel outer sheath 100 has the cylindrical shape. With respect to the longitudinal central axis, the length of the 0° portion parallel to the central axis, the length of the 90° portion, the length of the 180° portion, and the length of the 270° portion are the same, so that the lengths of all portions are unified. .

And referring to FIG. 2, the annular member 200 has a plurality of peak portions (P) and valley portions (V), and the lengths between adjacent peak portions of the plurality of peak portions are formed to be different from each other, The lengths between adjacent valley parts in the plurality of valley parts are formed to be different from each other.

In addition, referring to FIGS. 1 to 3, the bending response means has peaks adjacent to areas where each annular member 200 has the same angle with respect to the sheath 100, where each annular member 200 is disposed on the artificial blood vessel sheath 100. The length between the parts is arranged to be the same, so that when the angles of the cylindrical cross sections in the shell 100 are different, the length between adjacent peak parts or the length between valley parts of the annular member 200 is also arranged differently. When an artificial blood vessel is placed in a curved blood vessel, the artificial blood vessel is easily bent and placed.

Additionally, when the artificial blood vessel is installed in a curved blood vessel, the artificial blood vessel is bent to match the shape of the curved blood vessel.

At this time, if the average radius of the innermost part of the bent area in the curved artificial blood vessel is R1, and the average radius of the outermost part of the bent area is R2, the relationship between R1 and R2 is R1 < R2, and R1 When the length between adjacent peak portions of the annular member 200 in this location is L1, the length between adjacent peak portions of the annular member 200 gradually increases as it moves from the R1 portion to the R2 portion. is formed

In addition, the length between adjacent peak portions of the annular member 200 gradually increases as it moves from the R1 region to the R2 region, and the length is Li (where i = 1, 2, 3,..., n As -1,n), the length between the adjacent peak portions of the annular member 200 at the region where R2 is located is Ln, and the relationship between the sizes of Li is L1<L2<L3<...<Ln-1 It is provided so that <Ln.

Meanwhile, referring to FIGS. 4 to 6, the artificial blood vessel outer shell 100 is formed to form a cylindrical shape, and when the cross-section of the cylindrical shape is divided into four equal parts at 0°, 90°, 180°, and 270°, the artificial blood vessel The outer shell 100 has a length K1 at a 0° portion parallel to the central axis, a length K2 at a 90° portion, a length K3 at a 180° portion, and a length at a 270° portion with respect to the longitudinal central axis of the cylindrical shape. K4 is formed differently.

Therefore, when the artificial blood vessel shell 100 is unfolded to form a cylindrical shape so that the wrinkles are not folded, the artificial blood vessel has a bent shape, and a plurality of the annular members 200 are installed at regular intervals in the longitudinal direction with respect to the shell 100. and is provided to support the outer shell 100.

In addition, the bending response means arranges the annular member 200 in a cylindrical state by unfolding the outer skin 100 so that the wrinkles are not folded, and the central axis of the annular member 200 and the central axis of the artificial blood vessel are aligned. As the annular members 200 are arranged to overlap each other, the central axes of each annular member are aligned at equal intervals.

Additionally, when the artificial blood vessel is installed in a curved blood vessel, the artificial blood vessel is bent to match the shape of the curved blood vessel.

At this time, if the average radius of the innermost part of the bent area in the bent artificial blood vessel is P1 and the average radius of the outermost part of the bent area is P2, the relationship between P1 and P2 is preferably P1 < P2. .

In addition, as the cylindrical cross section of the outer shell 100 of the artificial blood vessel is installed at 0° at the area where the P1 is located, the length of the outer shell 100 of the artificial blood vessel 100 at the area where the P1 is located becomes K1, and the P1 area The length of the outer shell 100 becomes increasingly larger as it moves from to the P2 portion.

In addition, the length of the sheath 100 gradually increases from the P1 portion to the P2 portion, but the portion where the P2 is located coincides 180° with the cylindrical cross section of the sheath 100, so the length of the artificial blood vessel is K3. do.

And the relationship between K1, K2, K3, K4 is arranged so that K1 < K2, K3 > K4, and K2 = K4, so that when the artificial blood vessel is placed in a curved blood vessel, the length of the outer shell 100 is different. Make sure it can be easily bent and placed.

Meanwhile, referring to FIGS. 7 and 8, a marker 300 is disposed at a predetermined position on each annular member 200, and the marker 300 is preferably a radiation-opaque material that does not transmit radiation.

Additionally, the marker 300 is in the form of a spring and is formed by winding the wire of the annular member 200 in the longitudinal direction for a predetermined length.

In addition, when the length of one valley part directly connected to one peak part of the wire is M, the predetermined length E around which the marker 300 is wound is preferably M/3 < E < M/2.

In other words, if the marker is longer than the stomach length, it is inconvenient to operate or manage, and if it is shorter than the stomach length, it is difficult to recognize. In addition, the stomach marker is installed on all annular members, so when performing the procedure, the marker is placed inside the bend while watching the image. Operate to position.

In addition, the marker 300 is placed on the wire of the annular member 200 so that during the procedure, the position of the marker 300 is placed at the R1 or P1 region, which is the innermost part of the curved area when performing the artificial blood vessel treatment. do.

Therefore, Ln, which has the longest length between adjacent peaks of the annular member, is placed in the area located at R2 or P2, the outermost part of the bending area, or K4, which has the longest outer shell of the artificial blood vessel, is placed to improve the bending of the artificial blood vessel. It is desirable to make it easy to maintain.

Meanwhile, the artificial blood vessel outer shell 100 is made of polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polyurethane (PU), polypropylene (PP), and polyethylene (polyethylene, PE), polytetrafluoroethylene (PTFE), polytrimethyleneterephthalate (PTT), polyimide (PI), polyvinylchloride (PVC), polyvinyl alcohol (PVA), Polyvinylpyrrolidone (PVP), polyethyleneglycol (PEG), polysaccharide, polyolefin, nylon, polyether block amide (PEBA, Pebax), carbon fiber, Teflon ) and cotton.

Although the present invention has been described in detail through specific examples, this is for the purpose of explaining the present invention in detail, and the present invention is not limited thereto, and can be understood by those skilled in the art within the technical spirit of the present invention. It is clear that modifications and improvements are possible.

All simple modifications or changes of the present invention fall within the scope of the present invention, and the specific scope of protection of the present invention will be made clear by the appended claims.

10 ; Stent 100: Sheath 200: Annular member
300: Marker P: Peak part V: Valley part

Claims (7)

In the artificial blood vessel formed to operate normally when the blood vessel is damaged, it is installed at the damaged area,
An artificial blood vessel shell (100) that functions as a skin for the artificial blood vessel,
The artificial blood vessel shell 100 is made of an annular member 200 having a wave shape disposed along the circumferential surface of the shell 100 so that it maintains a cylindrical shape,
The annular member 200 is a wire having a wave wave and rotates once to form a plurality of peak portions (P) and valley portions (V),
The annular member 200 or the artificial blood vessel shell 100 is arranged so that the artificial blood vessel is curved.
When the artificial blood vessel is installed in a curved blood vessel, the artificial blood vessel is curved to match the shape of the curved blood vessel. At this time, the average radius of the innermost part of the curved area in the curved artificial blood vessel is R1, and the curved blood vessel is curved. If the average radius of the outermost part of the region is R2, the relationship between R1 and R2 is R1<R2,
When the length between adjacent peak portions of the annular member 200 in the region where R1 is located is L1, the length between adjacent peak portions of the annular member 200 becomes increasingly longer as it moves from the R1 region to the R2 region. It grows bigger,
The length between adjacent peak portions of the annular member 200 gradually increases as it moves from the R1 region to the R2 region,
As the length is Li (where i=1,2,3,...,n-1,n), the length between adjacent peak portions of the annular member 200 at the region where R2 is located is Ln. , the relationship between the sizes of Li is L1<L2<L3<...<Ln-1<Ln,
A marker 300 is placed at a predetermined position on each of the annular members 200,
The marker 300 is a radio-opaque material that does not transmit radiation, and the marker 300 is in the form of a spring and is formed by winding the wire of the annular member 200 in the longitudinal direction for a predetermined length,
At this time, if the length of one valley part directly connected to one peak part of the wire is M, the predetermined length E around which the marker 300 is wound is M/3 < E < M/2,
The marker 300 is placed on the wire of the annular member so that during the procedure, the position of the marker 300 is placed at the R1 region, which is the innermost part of the bent region when performing the artificial blood vessel treatment, so that it is positioned at the innermost part of the bent region. The cycle of the annular member is varied in preparation for the curvature of the blood vessel, characterized in that Ln, which has the longest length between adjacent peaks of the annular member, is placed in the area located at the outer portion R2 to easily maintain the curvature of the artificial blood vessel. Artificial blood vessel stent.
According to paragraph 1,
The artificial blood vessel shell 100 is formed to form a cylindrical shape, and when the cross-section of the cylindrical shape is divided into four equal parts at 0°, 90°, 180°, and 270°,
The outer skin 100 of the artificial blood vessel has a length of 0°, a length of 90°, a length of 180°, and a length of 270° parallel to the central axis of the cylindrical longitudinal direction. As they are identical, the lengths of all parts are formed to be unified,
The annular member 200 has a plurality of peak portions and valley portions,
The lengths between adjacent peak portions of the plurality of peak portions are formed to be different from each other,
An artificial blood vessel stent that varies the cycle of the annular member in preparation for the curvature of the blood vessel, characterized in that the lengths between the plurality of valley parts and adjacent valley parts are formed differently from each other.


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