KR102607107B1 - Coating composition for protecting fingernails and toenails and protection method using the same - Google Patents
Coating composition for protecting fingernails and toenails and protection method using the same Download PDFInfo
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- KR102607107B1 KR102607107B1 KR1020230105561A KR20230105561A KR102607107B1 KR 102607107 B1 KR102607107 B1 KR 102607107B1 KR 1020230105561 A KR1020230105561 A KR 1020230105561A KR 20230105561 A KR20230105561 A KR 20230105561A KR 102607107 B1 KR102607107 B1 KR 102607107B1
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- extract
- coating composition
- toenails
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- 239000008199 coating composition Substances 0.000 title claims abstract description 56
- 210000004906 toe nail Anatomy 0.000 title claims abstract description 43
- 210000004905 finger nail Anatomy 0.000 title claims abstract description 40
- 238000000034 method Methods 0.000 title description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 46
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 26
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 26
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims abstract description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 20
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims abstract description 13
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229960000458 allantoin Drugs 0.000 claims abstract description 13
- 235000011187 glycerol Nutrition 0.000 claims abstract description 13
- 229940065115 grapefruit extract Drugs 0.000 claims abstract description 13
- 239000000171 lavandula angustifolia l. flower oil Substances 0.000 claims abstract description 13
- 239000008213 purified water Substances 0.000 claims abstract description 13
- 229940092258 rosemary extract Drugs 0.000 claims abstract description 13
- 235000020748 rosemary extract Nutrition 0.000 claims abstract description 13
- 239000001233 rosmarinus officinalis l. extract Substances 0.000 claims abstract description 13
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims abstract description 13
- 235000010234 sodium benzoate Nutrition 0.000 claims abstract description 13
- 239000004299 sodium benzoate Substances 0.000 claims abstract description 13
- 229940094952 green tea extract Drugs 0.000 claims abstract description 12
- 235000020688 green tea extract Nutrition 0.000 claims abstract description 12
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229960000686 benzalkonium chloride Drugs 0.000 claims abstract description 11
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims abstract description 10
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims abstract description 10
- 229920000053 polysorbate 80 Polymers 0.000 claims abstract description 10
- 229940068968 polysorbate 80 Drugs 0.000 claims abstract description 10
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 30
- 239000000284 extract Substances 0.000 claims description 20
- 239000000843 powder Substances 0.000 claims description 18
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 claims description 14
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims description 14
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 claims description 14
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 claims description 14
- 238000000576 coating method Methods 0.000 claims description 13
- 238000002156 mixing Methods 0.000 claims description 13
- 239000000419 plant extract Substances 0.000 claims description 11
- 241000218691 Cupressaceae Species 0.000 claims description 9
- 241000218657 Picea Species 0.000 claims description 9
- 210000001808 exosome Anatomy 0.000 claims description 9
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 claims description 7
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 claims description 7
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 7
- 235000011299 Brassica oleracea var botrytis Nutrition 0.000 claims description 7
- 235000017647 Brassica oleracea var italica Nutrition 0.000 claims description 7
- 240000003259 Brassica oleracea var. botrytis Species 0.000 claims description 7
- 239000002126 C01EB10 - Adenosine Substances 0.000 claims description 7
- 240000004307 Citrus medica Species 0.000 claims description 7
- ATGQXSBKTQANOH-UWVGARPKSA-N N-oleoylphytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(=O)CCCCCCC\C=C/CCCCCCCC ATGQXSBKTQANOH-UWVGARPKSA-N 0.000 claims description 7
- 235000021314 Palmitic acid Nutrition 0.000 claims description 7
- 229920001800 Shellac Polymers 0.000 claims description 7
- 229960005305 adenosine Drugs 0.000 claims description 7
- 229940081733 cetearyl alcohol Drugs 0.000 claims description 7
- 239000003240 coconut oil Substances 0.000 claims description 7
- 235000019864 coconut oil Nutrition 0.000 claims description 7
- 229940087305 limonene Drugs 0.000 claims description 7
- 235000001510 limonene Nutrition 0.000 claims description 7
- 229930007744 linalool Natural products 0.000 claims description 7
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims description 7
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 7
- 239000011347 resin Substances 0.000 claims description 7
- 229920005989 resin Polymers 0.000 claims description 7
- 229940113147 shellac Drugs 0.000 claims description 7
- 239000004208 shellac Substances 0.000 claims description 7
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 claims description 7
- 235000013874 shellac Nutrition 0.000 claims description 7
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims description 7
- 229960000281 trometamol Drugs 0.000 claims description 7
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 6
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims description 6
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 6
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims description 6
- 244000196755 Hesperocyparis lusitanica Species 0.000 claims description 6
- 241000736199 Paeonia Species 0.000 claims description 6
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 6
- 238000004108 freeze drying Methods 0.000 claims description 6
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 6
- 229940010454 licorice Drugs 0.000 claims description 6
- 238000010298 pulverizing process Methods 0.000 claims description 6
- 239000006228 supernatant Substances 0.000 claims description 6
- 238000005406 washing Methods 0.000 claims description 6
- 229920002307 Dextran Polymers 0.000 claims description 3
- 240000001439 Opuntia Species 0.000 claims description 3
- 235000013389 Opuntia humifusa var. humifusa Nutrition 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 239000011812 mixed powder Substances 0.000 claims description 3
- 239000012046 mixed solvent Substances 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 239000000047 product Substances 0.000 claims description 3
- 244000303040 Glycyrrhiza glabra Species 0.000 claims 2
- 235000019441 ethanol Nutrition 0.000 abstract description 3
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 abstract 1
- 210000000282 nail Anatomy 0.000 description 31
- 238000002474 experimental method Methods 0.000 description 9
- 239000000203 mixture Substances 0.000 description 8
- 230000000694 effects Effects 0.000 description 7
- 230000000844 anti-bacterial effect Effects 0.000 description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 5
- 241000202807 Glycyrrhiza Species 0.000 description 4
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 230000000699 topical effect Effects 0.000 description 3
- WSWCOQWTEOXDQX-MQQKCMAXSA-M (E,E)-sorbate Chemical compound C\C=C\C=C\C([O-])=O WSWCOQWTEOXDQX-MQQKCMAXSA-M 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- 241000723368 Conium Species 0.000 description 2
- 102000011782 Keratins Human genes 0.000 description 2
- 108010076876 Keratins Proteins 0.000 description 2
- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 2
- 208000006187 Onycholysis Diseases 0.000 description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- -1 benzal Chemical class 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 229940075554 sorbate Drugs 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 210000003371 toe Anatomy 0.000 description 2
- 208000000412 Avitaminosis Diseases 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- 244000085625 Equisetum Species 0.000 description 1
- 208000028571 Occupational disease Diseases 0.000 description 1
- 206010048886 Onychoclasis Diseases 0.000 description 1
- 208000037581 Persistent Infection Diseases 0.000 description 1
- 241000519995 Stachys sylvatica Species 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 206010047627 Vitamin deficiencies Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 210000004904 fingernail bed Anatomy 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 235000009569 green tea Nutrition 0.000 description 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000036562 nail growth Effects 0.000 description 1
- 210000003463 organelle Anatomy 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229950008882 polysorbate Drugs 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000011253 protective coating Substances 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4993—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
Abstract
본 발명은 로즈마리 추출물, 자몽 추출물, 녹차 추출물, 알란토인, 라벤더오일, 벤잘코늄염화물, 디나트륨아디티에이, 글리세린, 부틸렌글리콜, 에탄올, 벤조산나트륨, 폴리소르베이트80, 스트르산, 과산화수소 및 정제수를 포함하는 손톱 및 발톱 보호용 코팅 조성물을 제공한다.The present invention includes rosemary extract, grapefruit extract, green tea extract, allantoin, lavender oil, benzalkonium chloride, disodium aditiate, glycerin, butylene glycol, ethanol, sodium benzoate, polysorbate 80, succinic acid, hydrogen peroxide and purified water. Provided is a coating composition for protecting fingernails and toenails.
Description
본 발명은 손톱, 발톱 보호용 코팅 조성물 및 이를 이용한 보호방법에 관한 것이다.The present invention relates to a coating composition for protecting fingernails and toenails and a protection method using the same.
일반적으로 손톱, 발톱이라함은 손가락 또는 발가락 말단 부위에 붙어 있는 반투명의 단단한 판 구조물을 칭한다. 경질 케라틴을 함유하는 각질화된 죽은 세포가 빽빽하게 모인 것으로 손가락의 보호 기능과 물건을 집는 등 손가락의 기능 수행에 도움을 준다.In general, fingernails and toenails refer to translucent, hard plate structures attached to the end of fingers or toes. It is a dense collection of dead keratinized cells containing hard keratin and helps protect the fingers and perform functions such as picking up objects.
손톱, 발톱은 손가락 또는 발가락의 등쪽면에 약간 휘어지며 자리 잡고 있는 단단한 케라틴을 함유하며 핵이나 세포소기관이 없고 각질화된 죽은 세포가 빽빽하게 모인 것이다. 손톱은 손톱 몸통, 손톱 바닥, 손톱 뿌리, 손톱 바탕질, 손톱 위허물, 손톱 아래허물, 손톱 초승달 등으로 이루어진다.Fingernails and toenails contain hard keratin that is slightly curved and located on the dorsal surface of the finger or toe, and are dense collections of dead, keratinized cells without a nucleus or organelles. The nail consists of the nail body, nail bed, nail root, nail matrix, nail skin, skin under the nail, and nail crescent.
건강하게 보이는 손톱들은 매끈하고, 곡면이며, 얼룩이 없어야 하고, 패인 곳(hollow)이나 돌기들이 없어야 한다. 건강하지 못한 상태들의 손톱들은 개인의 이미지에 매우 해로울 수 있으며, 방치되면, 장기적인 기능장애(embarassment) 및 고통과 관련된 만성 감염들을 유발할 수 있다. 특히, 그들은 사회적 문제 및/또는 직업병으로 간주될 수 있다.Healthy-looking nails should be smooth, curved, free of stains, and free of hollows or bumps. Unhealthy nails can be very detrimental to a person's self-image and, if left untreated, can cause chronic infections associated with long-term dysfunction and pain. In particular, they can be considered social problems and/or occupational diseases.
손톱들의 반복적이고 장기적인 습윤 및 건조는 손톱들의 갈라짐 및 돌기들을 유발하는 단일의 가장 흔한 원인이다. 손톱들의 갈라짐은 내과계 질환 또는 비타민 결핍에 의해 드물게 발생하며, 네일 폴리쉬(nail polish) 제거제는 조갑박렬증(층상 분열)을 유발하고, 종국적으로 손가락들에 대한 외상은 조갑박렬증에 기여한다.Repetitive and prolonged wetting and drying of the nails is the single most common cause of cracks and bumps in the nails. Cracked nails are rarely caused by internal diseases or vitamin deficiencies, nail polish remover causes onycholysis (lamellar splitting), and ultimately trauma to the fingers contributes to onycholysis.
손톱들의 미용상 손상들 중에는 떨어짐(breaking), 갈라짐(splitting), 깨짐(fracturing), 메짐(brittleness), 백색 얼룩들 또는 돌기들(white spots or ridges), 부진한 손톱 성장, 색상 및 형태 변화 등이 포함될 수 있다.Cosmetic damages to nails include breaking, splitting, fracturing, brittleness, white spots or ridges, poor nail growth, and changes in color and shape. You can.
상기와 같은 문제점을 해결하기 위하여, 대한민국 등록특허공보 제10-1140272호에는 국소 적용용 손톱 재건 조성물들이 개시된바 있는데, 이는, a) 하나 이상의 쇠뜨기 속(genus Equisetum) 약용 추출물(herb extract), b) 필름 형성제로서, 히드록시알킬 키토산류에서 선택된 하나 이상의 성분;을 포함하며, 상기 a)는 글리콜 추출물의 형태인 것인, 조갑박렬증(Onychoschizia)의 치료 또는 예방을 위한 국소 적용의 약학적 조성물에 관한 것으로, 양호한 손톱 재건, 경화 및 강화 효과를 갖는 조성물을 제공하고자 하는 것이다.In order to solve the above problems, Korean Patent Publication No. 10-1140272 discloses nail reconstruction compositions for topical application, which include: a) one or more medicinal extracts of the genus Equisetum, b ) As a film former, one or more components selected from the hydroxyalkyl chitosan family; wherein a) is in the form of a glycol extract, a pharmaceutical for topical application for the treatment or prevention of onychoschizia. The object is to provide a composition having a good nail reconstruction, hardening and strengthening effect.
그러나, 상기 종래의 국소 적용용 손톱 재건 조성물은 그 효과가 미미하여 손톱 재건, 경화 및 강화 효과에 뚜렷한 효과를 나타내지 못하는 문제점이 있었으며, 보다 근본적으로 손발톱을 강화할 수 있는 조성물에 대한 필요성이 커지는 추세이다.However, the conventional nail reconstruction composition for topical application has a problem in that it does not have a clear effect on nail reconstruction, hardening and strengthening effects due to its insignificant effect, and there is a growing need for a composition that can fundamentally strengthen nails.
본 발명은 상기와 같은 문제점을 해결하기 위해 안출된 것으로서, 본 발명의 목적은 손톱 또는 발톱을 살균 소독하여 케어가능하고, 동시에 손톱 또는 발톱에 손상 없이 손톱 또는 발톱을 보호하기 위한 조성물을 제공하는 것이다.The present invention was made to solve the above problems, and the purpose of the present invention is to provide a composition that can care for fingernails or toenails by sterilizing and disinfecting them, and at the same time protects the fingernails or toenails without damaging them. .
본 발명의 과제는 이상에서 언급한 과제들로 제한되지 않으며, 언급되지 않은 또 다른 과제들은 아래의 기재로부터 당업자에게 명확하게 이해될 수 있을 것이다.The object of the present invention is not limited to the problems mentioned above, and other problems not mentioned will be clearly understood by those skilled in the art from the description below.
상기 목적을 달성하기 위하여 본 발명은In order to achieve the above object, the present invention
로즈마리 추출물, 자몽 추출물, 녹차 추출물, 알란토인, 라벤더오일, 벤잘코늄염화물, 디나트륨아디티에이, 글리세린, 부틸렌글리콜, 에탄올, 벤조산나트륨, 폴리소르베이트80, 스트르산, 과산화수소 및 정제수를 포함하는 손톱 및 발톱 보호용 코팅 조성물을 제공한다.Nails containing rosemary extract, grapefruit extract, green tea extract, allantoin, lavender oil, benzalkonium chloride, disodium aditiate, glycerin, butylene glycol, ethanol, sodium benzoate, polysorbate 80, stric acid, hydrogen peroxide and purified water. A coating composition for protecting toenails is provided.
또한, 상기 손톱 및 발톱 보호용 코팅 조성물은 로즈마리 추출물 0.5-1.5 중량부, 자몽 추출물 0.5-1.5 중량부, 녹차 추출물 0.5-1.5 중량부, 알란토인 1-5 중량부, 라벤더오일 0.5-1.5 중량부, 벤잘코늄염화물 0.06-0.07 중량부, 디나트륨아디티에이 0.5-1.5 중량부, 글리세린 2-6 중량부, 부틸렌글리콜 1-5 중량부, 에탄올 13-17 중량부, 벤조산나트륨 1-5 중량부, 폴리소르베이트80 1-5 중량부, 시트르산 1-5 중량부, 과산화수소 0.13-0.14 중량부 및 정제수 60.4-61.2 중량부를 포함하는 것을 특징으로 한다.In addition, the coating composition for protecting fingernails and toenails includes 0.5-1.5 parts by weight of rosemary extract, 0.5-1.5 parts by weight of grapefruit extract, 0.5-1.5 parts by weight of green tea extract, 1-5 parts by weight of allantoin, 0.5-1.5 parts by weight of lavender oil, and benzal. Conium chloride 0.06-0.07 parts by weight, disodium ADTA 0.5-1.5 parts by weight, glycerin 2-6 parts by weight, butylene glycol 1-5 parts by weight, ethanol 13-17 parts by weight, sodium benzoate 1-5 parts by weight, poly It is characterized in that it contains 1-5 parts by weight of sorbate 80, 1-5 parts by weight of citric acid, 0.13-0.14 parts by weight of hydrogen peroxide, and 60.4-61.2 parts by weight of purified water.
또한, 본 발명은In addition, the present invention
로즈마리 추출물 0.5-1.5 중량부, 자몽 추출물 0.5-1.5 중량부, 녹차 추출물 0.5-1.5 중량부, 알란토인 1-5 중량부, 라벤더오일 0.5-1.5 중량부, 벤잘코늄염화물 0.06-0.07 중량부, 디나트륨아디티에이 0.5-1.5 중량부, 글리세린 2-6 중량부, 부틸렌글리콜 1-5 중량부, 에탄올 13-17 중량부, 벤조산나트륨 1-5 중량부, 폴리소르베이트80 1-5 중량부, 시트르산 1-5 중량부, 과산화수소 0.13-0.14 중량부 및 정제수 60.4-61.2 중량부를 포함하는 제1 코팅 조성물을 이용하여 손톱 또는 발톱에 전처리하는 단계; 및Rosemary extract 0.5-1.5 parts by weight, grapefruit extract 0.5-1.5 parts by weight, green tea extract 0.5-1.5 parts by weight, allantoin 1-5 parts by weight, lavender oil 0.5-1.5 parts by weight, benzalkonium chloride 0.06-0.07 parts by weight, disodium 0.5-1.5 parts by weight of Adita, 2-6 parts by weight of glycerin, 1-5 parts by weight of butylene glycol, 13-17 parts by weight of ethanol, 1-5 parts by weight of sodium benzoate, 1-5 parts by weight of polysorbate 80, citric acid Pre-treating fingernails or toenails using a first coating composition comprising 1-5 parts by weight, 0.13-0.14 parts by weight of hydrogen peroxide, and 60.4-61.2 parts by weight of purified water; and
셸락 수지 28-32 중량부, 무화과 복합추출물 1-5 중량부, 천연식물 추출물 1-5 중량부, 유자씨오일 0.5-1.5 중량부, 코코넛오일 0.3-0.7 중량부, 하이드로제네이티드레시틴 0.05-0.15 중량부, 세테아릴알코올 0.05-0.15 중량부, 아데노신 0.05-0.15 중량부, 세라마이드엔피 0.05-0.15 중량부, 팔미틱애씨드 0.05-0.15 중량부, 리모넨 0.5-1.5 중량부, 리날룰 0.5-1.5 중량부, 트로메타민 0.5-1.5 중량부, 에탄올 18-22 중량부 및 브로콜리수 37-41 중량부를 포함하는 제2 코팅 조성물을 이용하여 전처리한 손톱 또는 발톱을 코팅하는 단계;를 포함하고,Shellac resin 28-32 parts by weight, fig complex extract 1-5 parts by weight, natural plant extract 1-5 parts by weight, citron seed oil 0.5-1.5 parts by weight, coconut oil 0.3-0.7 parts by weight, hydrogenated lecithin 0.05-0.15 Parts by weight, cetearyl alcohol 0.05-0.15 parts by weight, adenosine 0.05-0.15 parts by weight, ceramide NP 0.05-0.15 parts by weight, palmitic acid 0.05-0.15 parts by weight, limonene 0.5-1.5 parts by weight, linalool 0.5-1.5 parts by weight A step of coating the pretreated fingernails or toenails with a second coating composition comprising 0.5-1.5 parts by weight of tromethamine, 18-22 parts by weight of ethanol, and 37-41 parts by weight of broccoli water,
상기 무화과 복합추출물은,The fig complex extract,
무화과, 작약 및 감초를 세척하여 18-22℃의 온도에서 80-120 MPa의 압력으로 8-12분 동안 전처리하는 단계; 전처리된 무화과, 작약 및 감초를 8:1:1의 중량비율로 혼합하고, 착즙하여 착즙액을 제조하는 단계; 상기 착즙액을 원심분리하여 엑소좀을 포함하는 상층액을 수득하는 단계; 상기 엑소좀을 포함하는 상층액을 동결건조하여 동결건조물을 제조하는 단계; 상기 동결건조물에 폴리에틸렌글리콜/덱스트란을 사용하여 수성 2상계를 형성하는 단계; 및 상기 수성 2상계 내 엑소좀이 농축된 하층액을 수득하는 단계;를 수행하여 제조되고,Washing figs, peonies and licorice and pretreating them at a temperature of 18-22°C and a pressure of 80-120 MPa for 8-12 minutes; Preparing juice by mixing pretreated figs, peonies, and licorice at a weight ratio of 8:1:1 and squeezing; Centrifuging the juice to obtain a supernatant containing exosomes; Preparing a lyophilisate by lyophilizing the supernatant containing the exosomes; Forming an aqueous two-phase system using polyethylene glycol/dextran in the freeze-dried product; and obtaining a lower layer solution in which exosomes in the aqueous two-phase system are concentrated,
상기 천연식물 추출물은,The natural plant extract is,
회화나무잎, 편백나무잎 및 가문비나무잎을 세척하고 동결건조한 후 분쇄하여 회화나무잎분말, 편백나무잎분말 및 가문비나무잎분말을 준비하는 단계; 준비된 회화나무잎분말, 편백나무잎분말 및 가문비나무잎분말을 1:1:1의 중량비율로 혼합한 혼합분말을 에탄올 및 아세톤을 1:1의 부피비로 혼합한 혼합 용매와 1:9의 중량비율로 혼합하고, 28-32℃의 온도에서 22-26시간 동안 추출하여 추출액을 제조하는 단계; 및 상기 추출액을 여과지로 여과하고, 여과된 여과액을 영하 48-52℃의 온도에서 감압농축 및 동결건조하는 단계;를 수행하여 제조되는 것을 특징으로 하는 손톱 및 발톱 보호방법을 제공한다.Washing, freeze-drying, and pulverizing P. cypress leaves, cypress leaves, and spruce leaves and pulverizing them to prepare P. cypress leaf powder, cypress leaf powder, and spruce leaf powder; The prepared mixed powder of prickly pear leaf powder, cypress leaf powder, and spruce leaf powder mixed at a weight ratio of 1:1:1 was mixed with a mixed solvent of ethanol and acetone at a volume ratio of 1:1 and a weight ratio of 1:9. Preparing an extract by mixing in proportions and extracting at a temperature of 28-32°C for 22-26 hours; and filtering the extract with filter paper, concentrating and freeze-drying the filtered filtrate at a temperature of -48-52°C.
본 발명에 따른 손톱 및 발톱 보호 조성물은 손톱 또는 발톱을 살균 소독하여 케어가능하고, 동시에 손톱 또는 발톱에 손상 없이 손톱 또는 발톱을 보호할 수 있다.The fingernail and toenail protection composition according to the present invention can sterilize and disinfect fingernails or toenails to care for them, and at the same time protect the fingernails or toenails without damaging them.
이하에서는 다양한 실시예를 보다 상세하게 설명한다. 본 명세서에 기재된 실시예는 다양하게 변형될 수 있다. 특정한 실시예가 상세한 설명에서 자세하게 설명될 수 있다. 그러나 개시된 특정한 실시 예는 다양한 실시예를 쉽게 이해하도록 하기 위한 것일 뿐이다. 따라서 개시된 특정 실시예에 의해 기술적 사상이 제한되는 것은 아니며, 발명의 사상 및 기술 범위에 포함되는 모든 균등물 또는 대체물을 포함하는 것으로 이해되어야 한다.Hereinafter, various embodiments will be described in more detail. The embodiments described herein may be modified in various ways. Specific embodiments may be described in detail in the detailed description. However, the specific embodiments disclosed are only intended to facilitate understanding of the various embodiments. Accordingly, the technical idea is not limited to the specific embodiments disclosed, and should be understood to include all equivalents or substitutes included in the spirit and technical scope of the invention.
1차, 2차, 제1, 제2 등과 같이 서수를 포함하는 용어는 다양한 구성요소들을 설명하는데 사용될 수 있지만, 이러한 구성요소들은 상술한 용어에 의해 한정되지는 않는다. 상술한 용어는 하나의 구성요소를 다른 구성요소로부터 구별하는 목적으로만 사용된다.Terms containing ordinal numbers, such as primary, secondary, first, second, etc., may be used to describe various components, but these components are not limited by the above-mentioned terms. The above-mentioned terms are used only for the purpose of distinguishing one component from another.
본 명세서에서, '포함한다' 또는 '가지다' 등의 용어는 명세서상에 기재된 특징, 숫자, 단계, 동작, 구성요소, 부품 또는 이들을 조합한 것이 존재함을 지정하려는 것이지, 하나 또는 그 이상의 다른 특징들이나 숫자, 단계, 동작, 구성요소, 부품 또는 이들을 조합한 것들의 존재 또는 부가 가능성을 미리 배제하지 않는 것으로 이해되어야 한다. 어떤 구성요소가 다른 구성요소에 '연결되어' 있다거나 '접속되어' 있다고 언급된 때에는, 그 다른 구성요소에 직접적으로 연결되어 있거나 또는 접속되어 있을 수도 있지만, 중간에 다른 구성요소가 존재할 수도 있다고 이해되어야 할 것이다. 반면에, 어떤 구성요소가 다른 구성요소에 '직접 연결되어' 있다거나 '직접 접속되어' 있다고 언급된 때에는, 중간에 다른 구성요소가 존재하지 않는 것으로 이해되어야 할 것이다.In this specification, terms such as 'include' or 'have' are intended to designate the presence of features, numbers, steps, operations, components, parts, or combinations thereof described in the specification, but are not intended to indicate the presence of one or more other features. It should be understood that this does not exclude in advance the possibility of the existence or addition of elements, numbers, steps, operations, components, parts, or combinations thereof. When a component is said to be 'connected' or 'connected' to another component, it is understood that it may be directly connected or connected to the other component, but that other components may exist in between. It should be. On the other hand, when a component is mentioned as being 'directly connected' or 'directly connected' to another component, it should be understood that there are no other components in between.
그 밖에도, 본 발명을 설명함에 있어서, 관련된 공지 기능 혹은 구성에 대한 구체적인 설명이 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 경우, 그에 대한 상세한 설명은 축약하거나 생략한다.In addition, when describing the present invention, if it is determined that a detailed description of a related known function or configuration may unnecessarily obscure the gist of the present invention, the detailed description thereof is abbreviated or omitted.
본 발명은This invention
로즈마리 추출물, 자몽 추출물, 녹차 추출물, 알란토인, 라벤더오일, 벤잘코늄염화물, 디나트륨아디티에이, 글리세린, 부틸렌글리콜, 에탄올, 벤조산나트륨, 폴리소르베이트80, 스트르산, 과산화수소 및 정제수를 포함하는 손톱 및 발톱 보호용 코팅 조성물을 제공한다.Nails containing rosemary extract, grapefruit extract, green tea extract, allantoin, lavender oil, benzalkonium chloride, disodium aditiate, glycerin, butylene glycol, ethanol, sodium benzoate, polysorbate 80, stric acid, hydrogen peroxide and purified water. A coating composition for protecting toenails is provided.
이하, 본 발명에 따른 손톱 및 발톱 보호용 코팅 조성물에 대하여 상세히 설명한다.Hereinafter, the coating composition for protecting fingernails and toenails according to the present invention will be described in detail.
상기 손톱 및 발톱 보호용 코팅 조성물은 로즈마리 추출물 0.5-1.5 중량부, 자몽 추출물 0.5-1.5 중량부, 녹차 추출물 0.5-1.5 중량부, 알란토인 1-5 중량부, 라벤더오일 0.5-1.5 중량부, 벤잘코늄염화물 0.06-0.07 중량부, 디나트륨아디티에이 0.5-1.5 중량부, 글리세린 2-6 중량부, 부틸렌글리콜 1-5 중량부, 에탄올 13-17 중량부, 벤조산나트륨 1-5 중량부, 폴리소르베이트80 1-5 중량부, 시트르산 1-5 중량부, 과산화수소 0.13-0.14 중량부 및 정제수 60.4-61.2 중량부를 포함하는 것이 바람직하고, 로즈마리 추출물 0.8-1.2 중량부, 자몽 추출물 0.8-1.2 중량부, 녹차 추출물 0.8-1.2 중량부, 알란토인 2-4 중량부, 라벤더오일 0.8-1.2 중량부, 벤잘코늄염화물 0.064-0.068 중량부, 디나트륨아디티에이 0.8-1.2 중량부, 글리세린 3-5 중량부, 부틸렌글리콜 2-4 중량부, 에탄올 14-16 중량부, 벤조산나트륨 2-4 중량부, 폴리소르베이트80 2-4 중량부, 시트르산 2-4 중량부, 과산화수소 0.132-0.136 중량부 및 정제수 60.6-61.0 중량부를 포함하는 것이 더욱 바람직하다.The coating composition for protecting fingernails and toenails includes 0.5-1.5 parts by weight of rosemary extract, 0.5-1.5 parts by weight of grapefruit extract, 0.5-1.5 parts by weight of green tea extract, 1-5 parts by weight of allantoin, 0.5-1.5 parts by weight of lavender oil, and benzalkonium chloride. 0.06-0.07 parts by weight, 0.5-1.5 parts by weight of disodium ADTA, 2-6 parts by weight of glycerin, 1-5 parts by weight of butylene glycol, 13-17 parts by weight of ethanol, 1-5 parts by weight of sodium benzoate, polysorbate It is preferable to include 1-5 parts by weight of 80, 1-5 parts by weight of citric acid, 0.13-0.14 parts by weight of hydrogen peroxide, and 60.4-61.2 parts by weight of purified water, 0.8-1.2 parts by weight of rosemary extract, 0.8-1.2 parts by weight of grapefruit extract, and green tea. Extract 0.8-1.2 parts by weight, allantoin 2-4 parts by weight, lavender oil 0.8-1.2 parts by weight, benzalkonium chloride 0.064-0.068 parts by weight, disodium ADTA 0.8-1.2 parts by weight, glycerin 3-5 parts by weight, butylene 2-4 parts by weight of glycol, 14-16 parts by weight of ethanol, 2-4 parts by weight of sodium benzoate, 2-4 parts by weight of polysorbate 80, 2-4 parts by weight of citric acid, 0.132-0.136 parts by weight of hydrogen peroxide and 60.6-61.0 parts by weight of purified water. It is more preferable to include parts by weight.
또한, 상기 손톱 및 발톱 보호용 코팅 조성물은 로즈마리 추출물 0.5-1.5 중량부, 자몽 추출물 0.5-1.5 중량부, 녹차 추출물 0.5-1.5 중량부, 알란토인 1-5 중량부, 라벤더오일 0.5-1.5 중량부, 벤잘코늄염화물 0.06-0.07 중량부, 디나트륨아디티에이 0.5-1.5 중량부, 글리세린 2-6 중량부, 부틸렌글리콜 1-5 중량부, 에탄올 13-17 중량부, 벤조산나트륨 1-5 중량부, 폴리소르베이트80 1-5 중량부, 시트르산 1-5 중량부, 과산화수소 0.13-0.14 중량부 및 정제수 60.4-61.2 중량부를 포함하는 제1 코팅 조성물 및 셸락 수지 28-32 중량부, 무화과 복합추출물 1-5 중량부, 천연식물 추출물 1-5 중량부, 유자씨오일 0.5-1.5 중량부, 코코넛오일 0.3-0.7 중량부, 하이드로제네이티드레시틴 0.05-0.15 중량부, 세테아릴알코올 0.05-0.15 중량부, 아데노신 0.05-0.15 중량부, 세라마이드엔피 0.05-0.15 중량부, 팔미틱애씨드 0.05-0.15 중량부, 리모넨 0.5-1.5 중량부, 리날룰 0.5-1.5 중량부, 트로메타민 0.5-1.5 중량부, 에탄올 18-22 중량부 및 브로콜리수 37-41 중량부를 포함하는 제2 코팅 조성물을 포함하는 것이 가장 바람직하다.In addition, the coating composition for protecting fingernails and toenails includes 0.5-1.5 parts by weight of rosemary extract, 0.5-1.5 parts by weight of grapefruit extract, 0.5-1.5 parts by weight of green tea extract, 1-5 parts by weight of allantoin, 0.5-1.5 parts by weight of lavender oil, and benzal. Conium chloride 0.06-0.07 parts by weight, disodium ADTA 0.5-1.5 parts by weight, glycerin 2-6 parts by weight, butylene glycol 1-5 parts by weight, ethanol 13-17 parts by weight, sodium benzoate 1-5 parts by weight, poly A first coating composition comprising 1-5 parts by weight of sorbate 80, 1-5 parts by weight of citric acid, 0.13-0.14 parts by weight of hydrogen peroxide, and 60.4-61.2 parts by weight of purified water, 28-32 parts by weight of shellac resin, and 1-5 parts by weight of fig complex extract. Parts by weight, natural plant extract 1-5 parts by weight, citron seed oil 0.5-1.5 parts by weight, coconut oil 0.3-0.7 parts by weight, hydrogenated lecithin 0.05-0.15 parts by weight, cetearyl alcohol 0.05-0.15 parts by weight, adenosine 0.05-0.15 parts by weight, Ceramide NP 0.05-0.15 parts by weight, Palmitic Acid 0.05-0.15 parts by weight, Limonene 0.5-1.5 parts by weight, Linalool 0.5-1.5 parts by weight, Tromethamine 0.5-1.5 parts by weight, Ethanol 18- It is most preferred to include a second coating composition comprising 22 parts by weight and 37-41 parts by weight broccoli water.
상기 제1 코팅 조성물과 제2 코팅 조성물의 혼합비율은 6-8:4-2의 중량비율인 것이 바람직하고, 7:3의 중량비율인 것이 더욱 바람직하다.The mixing ratio of the first coating composition and the second coating composition is preferably 6-8:4-2, and more preferably 7:3.
상기 제1 코팅 조성물과 제2 코팅 조성물이 7:3의 중량비율로 혼합된 손톱 및 발톱 보호용 코팅 조성물은 손톱 또는 발톱을 살균 소독하여 케어가능하고, 동시에 손톱 또는 발톱에 손상 없이 손톱 또는 발톱을 보호할 수 있다.The coating composition for protecting fingernails and toenails, in which the first coating composition and the second coating composition are mixed in a weight ratio of 7:3, can sterilize and disinfect fingernails or toenails, and at the same time protect fingernails or toenails without damaging them. can do.
또한, 본 발명은In addition, the present invention
로즈마리 추출물 0.5-1.5 중량부, 자몽 추출물 0.5-1.5 중량부, 녹차 추출물 0.5-1.5 중량부, 알란토인 1-5 중량부, 라벤더오일 0.5-1.5 중량부, 벤잘코늄염화물 0.06-0.07 중량부, 디나트륨아디티에이 0.5-1.5 중량부, 글리세린 2-6 중량부, 부틸렌글리콜 1-5 중량부, 에탄올 13-17 중량부, 벤조산나트륨 1-5 중량부, 폴리소르베이트80 1-5 중량부, 시트르산 1-5 중량부, 과산화수소 0.13-0.14 중량부 및 정제수 60.4-61.2 중량부를 포함하는 제1 코팅 조성물을 이용하여 손톱 또는 발톱에 전처리하는 단계; 및Rosemary extract 0.5-1.5 parts by weight, grapefruit extract 0.5-1.5 parts by weight, green tea extract 0.5-1.5 parts by weight, allantoin 1-5 parts by weight, lavender oil 0.5-1.5 parts by weight, benzalkonium chloride 0.06-0.07 parts by weight, disodium 0.5-1.5 parts by weight of Adita, 2-6 parts by weight of glycerin, 1-5 parts by weight of butylene glycol, 13-17 parts by weight of ethanol, 1-5 parts by weight of sodium benzoate, 1-5 parts by weight of polysorbate 80, citric acid Pre-treating fingernails or toenails using a first coating composition comprising 1-5 parts by weight, 0.13-0.14 parts by weight of hydrogen peroxide, and 60.4-61.2 parts by weight of purified water; and
셸락 수지 28-32 중량부, 무화과 복합추출물 1-5 중량부, 천연식물 추출물 1-5 중량부, 유자씨오일 0.5-1.5 중량부, 코코넛오일 0.3-0.7 중량부, 하이드로제네이티드레시틴 0.05-0.15 중량부, 세테아릴알코올 0.05-0.15 중량부, 아데노신 0.05-0.15 중량부, 세라마이드엔피 0.05-0.15 중량부, 팔미틱애씨드 0.05-0.15 중량부, 리모넨 0.5-1.5 중량부, 리날룰 0.5-1.5 중량부, 트로메타민 0.5-1.5 중량부, 에탄올 18-22 중량부 및 브로콜리수 37-41 중량부를 포함하는 제2 코팅 조성물을 이용하여 전처리한 손톱 또는 발톱을 코팅하는 단계;를 포함하는 손톱 또는 발톱 코팅방법을 제공한다.Shellac resin 28-32 parts by weight, fig complex extract 1-5 parts by weight, natural plant extract 1-5 parts by weight, citron seed oil 0.5-1.5 parts by weight, coconut oil 0.3-0.7 parts by weight, hydrogenated lecithin 0.05-0.15 Parts by weight, cetearyl alcohol 0.05-0.15 parts by weight, adenosine 0.05-0.15 parts by weight, ceramide NP 0.05-0.15 parts by weight, palmitic acid 0.05-0.15 parts by weight, limonene 0.5-1.5 parts by weight, linalool 0.5-1.5 parts by weight parts, 0.5-1.5 parts by weight of tromethamine, 18-22 parts by weight of ethanol, and 37-41 parts by weight of broccoli water, coating the pre-treated fingernails or toenails with a second coating composition. A coating method is provided.
이하, 본 발명에 따른 손톱 또는 발톱 코팅방법에 대하여 각 단계별로 상세히 설명한다.Hereinafter, the fingernail or toenail coating method according to the present invention will be described in detail in each step.
먼저, 본 발명에 따른 손톱 또는 발톱 코팅방법은 로즈마리 추출물 0.5-1.5 중량부, 자몽 추출물 0.5-1.5 중량부, 녹차 추출물 0.5-1.5 중량부, 알란토인 1-5 중량부, 라벤더오일 0.5-1.5 중량부, 벤잘코늄염화물 0.06-0.07 중량부, 디나트륨아디티에이 0.5-1.5 중량부, 글리세린 2-6 중량부, 부틸렌글리콜 1-5 중량부, 에탄올 13-17 중량부, 벤조산나트륨 1-5 중량부, 폴리소르베이트80 1-5 중량부, 시트르산 1-5 중량부, 과산화수소 0.13-0.14 중량부 및 정제수 60.4-61.2 중량부를 포함하는 제1 코팅 조성물을 이용하여 손톱 또는 발톱에 전처리하는 단계를 포함한다.First, the fingernail or toenail coating method according to the present invention includes 0.5-1.5 parts by weight of rosemary extract, 0.5-1.5 parts by weight of grapefruit extract, 0.5-1.5 parts by weight of green tea extract, 1-5 parts by weight of allantoin, and 0.5-1.5 parts by weight of lavender oil. , Benzalkonium chloride 0.06-0.07 parts by weight, disodium ADTA 0.5-1.5 parts by weight, glycerin 2-6 parts by weight, butylene glycol 1-5 parts by weight, ethanol 13-17 parts by weight, sodium benzoate 1-5 parts by weight , pre-treating fingernails or toenails using a first coating composition comprising 1-5 parts by weight of polysorbate 80, 1-5 parts by weight of citric acid, 0.13-0.14 parts by weight of hydrogen peroxide, and 60.4-61.2 parts by weight of purified water. .
상기 손톱 또는 발톱 코팅방법은 제1 코팅 조성물을 이용하여 손톱 또는 발톱에 전처리하고, 이후 제2 코팅 조성물을 이용하여 손톱 또는 발톱을 코팅한다.In the fingernail or toenail coating method, the fingernails or toenails are pretreated using a first coating composition, and then the fingernails or toenails are coated using a second coating composition.
상기 제1 코팅 조성물을 이용하여 손톱 또는 발톱에 전처리한 후 3-7분 동안 건조하는 단계를 더 포함할 수 있다.It may further include pre-treating the fingernails or toenails using the first coating composition and then drying them for 3-7 minutes.
다음으로, 본 발명에 따른 손톱 또는 발톱 코팅방법은 셸락 수지 28-32 중량부, 무화과 복합추출물 1-5 중량부, 천연식물 추출물 1-5 중량부, 유자씨오일 0.5-1.5 중량부, 코코넛오일 0.3-0.7 중량부, 하이드로제네이티드레시틴 0.05-0.15 중량부, 세테아릴알코올 0.05-0.15 중량부, 아데노신 0.05-0.15 중량부, 세라마이드엔피 0.05-0.15 중량부, 팔미틱애씨드 0.05-0.15 중량부, 리모넨 0.5-1.5 중량부, 리날룰 0.5-1.5 중량부, 트로메타민 0.5-1.5 중량부, 에탄올 18-22 중량부 및 브로콜리수 37-41 중량부를 포함하는 제2 코팅 조성물을 이용하여 전처리한 손톱 또는 발톱을 코팅하는 단계를 포함한다.Next, the fingernail or toenail coating method according to the present invention includes 28-32 parts by weight of shellac resin, 1-5 parts by weight of fig complex extract, 1-5 parts by weight of natural plant extract, 0.5-1.5 parts by weight of citron seed oil, and coconut oil. 0.3-0.7 parts by weight, hydrogenated lecithin 0.05-0.15 parts by weight, cetearyl alcohol 0.05-0.15 parts by weight, adenosine 0.05-0.15 parts by weight, ceramide NP 0.05-0.15 parts by weight, palmitic acid 0.05-0.15 parts by weight, Nails pretreated using a second coating composition comprising 0.5-1.5 parts by weight of limonene, 0.5-1.5 parts by weight of linalool, 0.5-1.5 parts by weight of tromethamine, 18-22 parts by weight of ethanol, and 37-41 parts by weight of broccoli water. or coating the toenail.
상기 단계에서는 제1 코팅 조성물을 이용하여 전처리된 손톱 또는 발톱에 제2 코팅 조성물을 이용하여 코팅한다.In this step, the fingernails or toenails pretreated with the first coating composition are coated with the second coating composition.
상기 무화과 복합추출물은,The fig complex extract,
무화과, 작약 및 감초를 세척하여 18-22℃의 온도에서 80-120 MPa의 압력으로 8-12분 동안 전처리하는 단계; 전처리된 무화과, 작약 및 감초를 8:1:1의 중량비율로 혼합하고, 착즙하여 착즙액을 제조하는 단계; 상기 착즙액을 원심분리하여 엑소좀을 포함하는 상층액을 수득하는 단계; 상기 엑소좀을 포함하는 상층액을 동결건조하여 동결건조물을 제조하는 단계; 상기 동결건조물에 폴리에틸렌글리콜/덱스트란을 사용하여 수성 2상계를 형성하는 단계; 및 상기 수성 2상계 내 엑소좀이 농축된 하층액을 수득하는 단계;를 수행하여 제조되는 것을 사용한다.Washing figs, peonies and licorice and pretreating them at a temperature of 18-22°C and a pressure of 80-120 MPa for 8-12 minutes; Preparing juice by mixing pretreated figs, peonies, and licorice at a weight ratio of 8:1:1 and squeezing; Centrifuging the juice to obtain a supernatant containing exosomes; Preparing a lyophilisate by lyophilizing the supernatant containing the exosomes; Forming an aqueous two-phase system using polyethylene glycol/dextran in the freeze-dried product; and obtaining a lower layer solution in which exosomes are concentrated in the aqueous two-phase system.
상기 무화과 복합추출물을 적용하여 손톱 또는 발톱에 영양성분 공급과 함께 보호코팅을 유지하는 효과가 있다.Applying the fig complex extract has the effect of supplying nutrients to fingernails or toenails and maintaining a protective coating.
상기 천연식물 추출물은,The natural plant extract is,
회화나무잎, 편백나무잎 및 가문비나무잎을 세척하고 동결건조한 후 분쇄하여 회화나무잎분말, 편백나무잎분말 및 가문비나무잎분말을 준비하는 단계; 준비된 회화나무잎분말, 편백나무잎분말 및 가문비나무잎분말을 1:1:1의 중량비율로 혼합한 혼합분말을 에탄올 및 아세톤을 1:1의 부피비로 혼합한 혼합 용매와 1:9의 중량비율로 혼합하고, 28-32℃의 온도에서 22-26시간 동안 추출하여 추출액을 제조하는 단계; 및 상기 추출액을 여과지로 여과하고, 여과된 여과액을 영하 48-52℃의 온도에서 감압농축 및 동결건조하는 단계;를 수행하여 제조되는 것을 사용한다.Washing, freeze-drying, and pulverizing P. cypress leaves, cypress leaves, and spruce leaves and pulverizing them to prepare P. cypress leaf powder, cypress leaf powder, and spruce leaf powder; The prepared mixed powder of prickly pear leaf powder, cypress leaf powder, and spruce leaf powder mixed at a weight ratio of 1:1:1 was mixed with a mixed solvent of ethanol and acetone at a volume ratio of 1:1 and a weight ratio of 1:9. Preparing an extract by mixing in proportions and extracting at a temperature of 28-32°C for 22-26 hours; and filtering the extract with filter paper, concentrating and freeze-drying the filtered filtrate at a temperature of -48-52°C under reduced pressure.
상기 천연식물 추출물을 적용하여 손톱 또는 발톱에 영양성분 공급과 함께 수분 공급성을 높일 수 있다.By applying the natural plant extract, it is possible to increase moisture supply as well as supply nutrients to fingernails or toenails.
나아가, 본 발명은Furthermore, the present invention
로즈마리 추출물 0.5-1.5 중량부, 자몽 추출물 0.5-1.5 중량부, 녹차 추출물 0.5-1.5 중량부, 알란토인 1-5 중량부, 라벤더오일 0.5-1.5 중량부, 벤잘코늄염화물 0.06-0.07 중량부, 디나트륨아디티에이 0.5-1.5 중량부, 글리세린 2-6 중량부, 부틸렌글리콜 1-5 중량부, 에탄올 13-17 중량부, 벤조산나트륨 1-5 중량부, 폴리소르베이트80 1-5 중량부, 시트르산 1-5 중량부, 과산화수소 0.13-0.14 중량부 및 정제수 60.4-61.2 중량부를 혼합하여 제1 코팅 조성물을 제조하는 단계;Rosemary extract 0.5-1.5 parts by weight, grapefruit extract 0.5-1.5 parts by weight, green tea extract 0.5-1.5 parts by weight, allantoin 1-5 parts by weight, lavender oil 0.5-1.5 parts by weight, benzalkonium chloride 0.06-0.07 parts by weight, disodium 0.5-1.5 parts by weight of Adita, 2-6 parts by weight of glycerin, 1-5 parts by weight of butylene glycol, 13-17 parts by weight of ethanol, 1-5 parts by weight of sodium benzoate, 1-5 parts by weight of polysorbate 80, citric acid Preparing a first coating composition by mixing 1-5 parts by weight, 0.13-0.14 parts by weight of hydrogen peroxide, and 60.4-61.2 parts by weight of purified water;
셸락 수지 28-32 중량부, 무화과 복합추출물 1-5 중량부, 천연식물 추출물 1-5 중량부, 유자씨오일 0.5-1.5 중량부, 코코넛오일 0.3-0.7 중량부, 하이드로제네이티드레시틴 0.05-0.15 중량부, 세테아릴알코올 0.05-0.15 중량부, 아데노신 0.05-0.15 중량부, 세라마이드엔피 0.05-0.15 중량부, 팔미틱애씨드 0.05-0.15 중량부, 리모넨 0.5-1.5 중량부, 리날룰 0.5-1.5 중량부, 트로메타민 0.5-1.5 중량부, 에탄올 18-22 중량부 및 브로콜리수 37-41 중량부를 혼합하여 제2 코팅 조성물을 제조하는 단계;Shellac resin 28-32 parts by weight, fig complex extract 1-5 parts by weight, natural plant extract 1-5 parts by weight, citron seed oil 0.5-1.5 parts by weight, coconut oil 0.3-0.7 parts by weight, hydrogenated lecithin 0.05-0.15 Parts by weight, cetearyl alcohol 0.05-0.15 parts by weight, adenosine 0.05-0.15 parts by weight, ceramide NP 0.05-0.15 parts by weight, palmitic acid 0.05-0.15 parts by weight, limonene 0.5-1.5 parts by weight, linalool 0.5-1.5 parts by weight preparing a second coating composition by mixing 0.5-1.5 parts by weight of tromethamine, 18-22 parts by weight of ethanol, and 37-41 parts by weight of broccoli water;
상기 제1 코팅 조성물 및 제2 코팅 조성물을 6-8:4-2의 중량비율로 혼합하여 혼합 코팅 조성물을 제조하는 단계; 및 Preparing a mixed coating composition by mixing the first coating composition and the second coating composition at a weight ratio of 6-8:4-2; and
상기 혼합 코팅 조성물을 손톱 또는 발톱에 도포하는 단계;를 포함하는 손톱 또는 발톱 코팅방법을 제공한다.It provides a fingernail or toenail coating method comprising: applying the mixed coating composition to fingernails or toenails.
상기 손톱 또는 발톱 코팅방법은 제1 코팅 조성물과 제2 코팅 조성물을 혼합하여 제조한 혼합 코팅 조성물을 이용하여 한번에 손톱 또는 발톱을 코팅하는 방법으로, 상기 공정을 통해 손톱 또는 발톱을 보호할 수 있다.The fingernail or toenail coating method is a method of coating fingernails or toenails at once using a mixed coating composition prepared by mixing the first coating composition and the second coating composition, and the fingernails or toenails can be protected through the above process.
이하, 본 발명을 하기의 실시예에 의해 보다 상세하게 설명한다.Hereinafter, the present invention will be explained in more detail by the following examples.
단, 하기 실시예는 본 발명의 내용을 예시하는 것일 뿐 발명의 범위가 실시예 및 실험예에 의해 한정되는 것은 아니다.However, the following examples only illustrate the content of the present invention and the scope of the invention is not limited by the examples and experimental examples.
<실시예 1> 제1 코팅 조성물의 제조<Example 1> Preparation of the first coating composition
로즈마리 추출물 1 중량부, 자몽 추출물 1 중량부, 녹차 추출물 1 중량부, 알란토인 3 중량부, 라벤더오일 1 중량부, 벤잘코늄염화물 0.066 중량부, 디나트륨아디티에이 1 중량부, 글리세린 4 중량부, 부틸렌글리콜 3 중량부, 에탄올 15 중량부, 벤조산나트륨 3 중량부, 폴리소르베이트80 3 중량부, 시트르산 3 중량부, 과산화수소 0.134 중량부 및 정제수 60.8 중량부를 혼합하여 제1 코팅 조성물을 제조하였다.1 part by weight of rosemary extract, 1 part by weight of grapefruit extract, 1 part by weight of green tea extract, 3 parts by weight of allantoin, 1 part by weight of lavender oil, 0.066 parts by weight of benzalkonium chloride, 1 part by weight of disodium ADTA, 4 parts by weight of glycerin, butyl A first coating composition was prepared by mixing 3 parts by weight of ren glycol, 15 parts by weight of ethanol, 3 parts by weight of sodium benzoate, 3 parts by weight of polysorbate 80, 3 parts by weight of citric acid, 0.134 parts by weight of hydrogen peroxide, and 60.8 parts by weight of purified water.
<실시예 2> 제2 코팅 조성물의 제조<Example 2> Preparation of second coating composition
셸락 수지 30 중량부, 무화과 복합추출물 3 중량부, 천연식물 추출물 3 중량부, 유자씨오일 1 중량부, 코코넛오일 0.5 중량부, 하이드로제네이티드레시틴 0.1 중량부, 세테아릴알코올 0.1 중량부, 아데노신 0.1 중량부, 세라마이드엔피 0.1 중량부, 팔미틱애씨드 0.1 중량부, 리모넨 1 중량부, 리날룰 1 중량부, 트로메타민 1 중량부, 에탄올 20 중량부 및 브로콜리수 39 중량부를 혼합하여 제2 코팅 조성물을 제조하였다.30 parts by weight of shellac resin, 3 parts by weight of fig complex extract, 3 parts by weight of natural plant extract, 1 part by weight of citron seed oil, 0.5 part by weight of coconut oil, 0.1 part by weight of hydrogenated lecithin, 0.1 part by weight of cetearyl alcohol, adenosine 0.1 part by weight, 0.1 part by weight of Ceramide NP, 0.1 part by weight of palmitic acid, 1 part by weight of limonene, 1 part by weight of linalool, 1 part by weight of tromethamine, 20 parts by weight of ethanol and 39 parts by weight of broccoli water for a second coating. A composition was prepared.
<실시예 3> 혼합 코팅 조성물의 제조<Example 3> Preparation of mixed coating composition
상기 실시예 1에서 제조된 제1 코팅 조성물 및 상기 실시예 2에서 제조된 제2 코팅 조성물을 7:3의 중량비율로 혼합하여 혼합 코팅 조성물을 제조하였다.A mixed coating composition was prepared by mixing the first coating composition prepared in Example 1 and the second coating composition prepared in Example 2 at a weight ratio of 7:3.
<실험예 1> 항균 실험<Experimental Example 1> Antibacterial experiment
상기 실시예 1에서 제조된 제1 코팅 조성물의 항균 성능을 확인하기 위하여, 상기 실시예 1에서 제조된 제1 코팅 조성물을 이용하여 항균시험을 수행하였다. 접종균 세균농도(CFU/mL)는 황색포도상구균 2.2×105, 녹농균 2.4×105이다. 비교를 위해 대조군으로 공시험군(blank)을 사용하였다. 시험결과를 하기 표 1에 나타내었다.In order to confirm the antibacterial performance of the first coating composition prepared in Example 1, an antibacterial test was performed using the first coating composition prepared in Example 1. The inoculant bacterial concentration (CFU/mL) was 2.2×10 5 for Staphylococcus aureus and 2.4×10 5 for Pseudomonas aeruginosa. For comparison, a blank test group was used as a control group. The test results are shown in Table 1 below.
(CFU/ml)initial concentration
(CFU/ml)
(CFU/ml)Concentration after 18 hours
(CFU/ml)
(%)Bacteriostatic reduction rate
(%)
항균시험caused by Pseudomonas aeruginosa
Antibacterial test
상기 표 1에 나타낸 바와 같이, 본 발명에 따른 코팅 조성물의 항균 성능을 확인할 수 있었다.As shown in Table 1, the antibacterial performance of the coating composition according to the present invention was confirmed.
<실험예 2> 손톱 케어 효능 실험<Experimental Example 2> Nail care efficacy experiment
상기 실시예 1-3에서 제조된 코팅 조성물의 손톱 케어 효능을 확인하기 위하여, 상기 실시예 1-3에서 제조된 코팅 조성물을 이용하여 아래와 같이 실험을 수행하였다. 20-30대 성인여자 20명씩 3군을 선정하고 대상 인원들의 왼손 손톱에 실시예 1의 코팅 조성물을 100 ㎕ 정도 도포한 것(실험 1), 대상 인원들의 왼손 손톱에 실시예 1의 코팅 조성물을 100 ㎕ 정도 도포하고 5분 뒤 실시예 2의 코팅 조성물을 100 ㎕ 정도 도포 정도 도포한 것(실험 2), 대상 인원들의 왼손 손톱에 실시예 3의 코팅 조성물을 100 ㎕ 정도 도포한 것(실험 3)을 각각 10일 동안 수행하여 손톱 표면의 매끄러움, 윤기 그리고 강도를 아무것도 처리하지 않은 오른손 손톱과 비교하여 효능 및 지속성을 5점 척도법을 이용하여 평가하였으며 그 결과를 하기 표 2에 나타내었다.In order to confirm the nail care efficacy of the coating composition prepared in Example 1-3, an experiment was performed as follows using the coating composition prepared in Example 1-3. Three groups of 20 adult women in their 20s and 30s were selected, and about 100 ㎕ of the coating composition of Example 1 was applied to the nails of the left hands of the target people (Experiment 1). The coating composition of Example 1 was applied to the nails of the left hands of the target people. About 100 μl was applied and 5 minutes later, about 100 μl of the coating composition of Example 2 was applied (Experiment 2), and about 100 μl of the coating composition of Example 3 was applied to the left hand nails of the subjects (Experiment 3). ) were each performed for 10 days, and the smoothness, gloss, and strength of the nail surface were compared with the untreated right hand nails, and efficacy and sustainability were evaluated using a 5-point scale. The results are shown in Table 2 below.
1 : 매우 그렇지 않다1: Very disagree
2 : 그렇지 않다2: No
3 : 비슷하다3: Similar
4 : 그렇다4: Yes
5 : 매우 그렇다5: Very true
상기 표 2에 나타낸 바와 같이, 본 발명에 따른 손톱 또는 발톱 보호용 조성물을 이용하는 경우 케어 효과가 우수한 것을 확인할 수 있었다. 특히, 제1 코팅 조성물과 제2 코팅 조성물을 순차적으로 처리하는 경우 가장 우수한 케어 효과를 나타냄을 확인할 수 있었다.As shown in Table 2 above, it was confirmed that the care effect was excellent when using the composition for protecting fingernails or toenails according to the present invention. In particular, it was confirmed that the best care effect was achieved when the first coating composition and the second coating composition were treated sequentially.
Claims (3)
셸락 수지 28-32 중량부, 무화과 복합추출물 1-5 중량부, 천연식물 추출물 1-5 중량부, 유자씨오일 0.5-1.5 중량부, 코코넛오일 0.3-0.7 중량부, 하이드로제네이티드레시틴 0.05-0.15 중량부, 세테아릴알코올 0.05-0.15 중량부, 아데노신 0.05-0.15 중량부, 세라마이드엔피 0.05-0.15 중량부, 팔미틱애씨드 0.05-0.15 중량부, 리모넨 0.5-1.5 중량부, 리날룰 0.5-1.5 중량부, 트로메타민 0.5-1.5 중량부, 에탄올 18-22 중량부 및 브로콜리수 37-41 중량부를 포함하는 제2 코팅 조성물을 이용하여 전처리한 손톱 또는 발톱을 코팅하는 단계;를 포함하고,
상기 무화과 복합추출물은,
무화과, 작약 및 감초를 세척하여 18-22℃의 온도에서 80-120 MPa의 압력으로 8-12분 동안 전처리하는 단계; 전처리된 무화과, 작약 및 감초를 8:1:1의 중량비율로 혼합하고, 착즙하여 착즙액을 제조하는 단계; 상기 착즙액을 원심분리하여 엑소좀을 포함하는 상층액을 수득하는 단계; 상기 엑소좀을 포함하는 상층액을 동결건조하여 동결건조물을 제조하는 단계; 상기 동결건조물에 폴리에틸렌글리콜/덱스트란을 사용하여 수성 2상계를 형성하는 단계; 및 상기 수성 2상계 내 엑소좀이 농축된 하층액을 수득하는 단계;를 수행하여 제조되고,
상기 천연식물 추출물은,
회화나무잎, 편백나무잎 및 가문비나무잎을 세척하고 동결건조한 후 분쇄하여 회화나무잎분말, 편백나무잎분말 및 가문비나무잎분말을 준비하는 단계; 준비된 회화나무잎분말, 편백나무잎분말 및 가문비나무잎분말을 1:1:1의 중량비율로 혼합한 혼합분말을 에탄올 및 아세톤을 1:1의 부피비로 혼합한 혼합 용매와 1:9의 중량비율로 혼합하고, 28-32℃의 온도에서 22-26시간 동안 추출하여 추출액을 제조하는 단계; 및 상기 추출액을 여과지로 여과하고, 여과된 여과액을 영하 48-52℃의 온도에서 감압농축 및 동결건조하는 단계;를 수행하여 제조되는 것을 특징으로 하는 손톱 및 발톱 보호방법.Rosemary extract 0.5-1.5 parts by weight, grapefruit extract 0.5-1.5 parts by weight, green tea extract 0.5-1.5 parts by weight, allantoin 1-5 parts by weight, lavender oil 0.5-1.5 parts by weight, benzalkonium chloride 0.06-0.07 parts by weight, disodium 0.5-1.5 parts by weight of Adita, 2-6 parts by weight of glycerin, 1-5 parts by weight of butylene glycol, 13-17 parts by weight of ethanol, 1-5 parts by weight of sodium benzoate, 1-5 parts by weight of polysorbate 80, citric acid Pre-treating fingernails or toenails using a first coating composition comprising 1-5 parts by weight, 0.13-0.14 parts by weight of hydrogen peroxide, and 60.4-61.2 parts by weight of purified water; and
Shellac resin 28-32 parts by weight, fig complex extract 1-5 parts by weight, natural plant extract 1-5 parts by weight, citron seed oil 0.5-1.5 parts by weight, coconut oil 0.3-0.7 parts by weight, hydrogenated lecithin 0.05-0.15 Parts by weight, cetearyl alcohol 0.05-0.15 parts by weight, adenosine 0.05-0.15 parts by weight, ceramide NP 0.05-0.15 parts by weight, palmitic acid 0.05-0.15 parts by weight, limonene 0.5-1.5 parts by weight, linalool 0.5-1.5 parts by weight A step of coating the pretreated fingernails or toenails with a second coating composition comprising 0.5-1.5 parts by weight of tromethamine, 18-22 parts by weight of ethanol, and 37-41 parts by weight of broccoli water,
The fig complex extract,
Washing figs, peonies and licorice and pretreating them at a temperature of 18-22°C and a pressure of 80-120 MPa for 8-12 minutes; Preparing juice by mixing pretreated figs, peonies, and licorice at a weight ratio of 8:1:1 and squeezing; Centrifuging the juice to obtain a supernatant containing exosomes; Preparing a lyophilisate by lyophilizing the supernatant containing the exosomes; Forming an aqueous two-phase system using polyethylene glycol/dextran in the freeze-dried product; and obtaining a lower layer solution in which exosomes in the aqueous two-phase system are concentrated,
The natural plant extract is,
Washing, freeze-drying, and pulverizing P. cypress leaves, cypress leaves, and spruce leaves and pulverizing them to prepare P. cypress leaf powder, cypress leaf powder, and spruce leaf powder; The prepared mixed powder of prickly pear leaf powder, cypress leaf powder, and spruce leaf powder mixed at a weight ratio of 1:1:1 was mixed with a mixed solvent of ethanol and acetone at a volume ratio of 1:1 and a weight ratio of 1:9. Preparing an extract by mixing in proportions and extracting at a temperature of 28-32°C for 22-26 hours; and filtering the extract with filter paper, concentrating the filtered filtrate under reduced pressure and freeze-drying at a temperature of -48-52°C.
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| KR1020230105561A KR102607107B1 (en) | 2023-08-11 | 2023-08-11 | Coating composition for protecting fingernails and toenails and protection method using the same |
| KR1020230105606A KR102607108B1 (en) | 2023-08-11 | 2023-08-11 | Coating composition for nail and toenail care, composite coating composition comprising the same, and care method using the same |
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| KR20220028733A (en) * | 2020-08-31 | 2022-03-08 | 주식회사 비앤에이치웍스 | Composition for strengthening nails and manufacturing method thereof |
| KR20230070144A (en) * | 2021-11-13 | 2023-05-22 | 지성산업 주식회사 | Fig lavation with main ingredient including fig extract |
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| KR20220028733A (en) * | 2020-08-31 | 2022-03-08 | 주식회사 비앤에이치웍스 | Composition for strengthening nails and manufacturing method thereof |
| KR20230070144A (en) * | 2021-11-13 | 2023-05-22 | 지성산업 주식회사 | Fig lavation with main ingredient including fig extract |
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| Title |
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| https://blog.naver.com/constg1717/223025206225, 네이버블로그, 발톱무좀약 요모클리어 무좀균인 백선균 99.999% 항균작용, 2023.02.23. * |
| https://blog.naver.com/lepechemignon/223064291109, 네이버블로그, 요모클리어, 깨지고 갈라진 손발톱 영양제, 2023.04.04. * |
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