KR102588579B1 - Available apparatus for monitoring patient in hyperbaric chamber - Google Patents

Abstract

A patient monitoring device for an oxygen chamber is disclosed. The patient monitoring device for an oxygen chamber includes a biosignal measuring unit that measures the user's biosignals located within the oxygen chamber; and a control unit that adjusts the measurement value measured by the bio-signal measurement unit, wherein the control unit can adjust the measurement value using at least one of pressure information and oxygen concentration information inside the oxygen chamber.

Description

Patient monitoring device that can be used in a high pressure chamber environment {AVAILABLE APPARATUS FOR MONITORING PATIENT IN HYPERBARIC CHAMBER}

This disclosure relates to a patient monitoring device for an oxygen chamber.

Generally, hyperbaric oxygen therapy places a patient in a chamber where a pressure higher than atmospheric pressure is created, and provides high concentrations (e.g., 22-25v/v%) of oxygen to induce oxygen to penetrate the patient's blood and capillaries. It is well known as a treatment method that quickly supplies high concentration of oxygen. In this regard, technology for a chamber for hyperbaric oxygen treatment has been presented in Republic of Korea Patent Publication No. 10-1752747.

Meanwhile, compared to the invasive blood pressure measurement method, which measures internal pressure by cutting the patient's artery and inserting a catheter directly into the artery, the non-invasive blood pressure measurement method has the advantage of being relatively convenient to measure. An example of a blood pressure measurement method is the oscillometric method. Specifically, the oscillometric method is a method of measuring systolic and diastolic blood pressure by sufficiently pressurizing the brachial artery with a cuff to block arterial blood flow and then having a pressure sensor detect the vibration of the blood vessel that occurs during the decompression process.

In addition, to measure oxygen saturation invasively, a blood gas test (Arterial Blood Gas Analysis, ABGA) must be performed by directly collecting the patient's arterial blood, whereas a pulse oximeter must be inserted into the patient's finger and photoplethysmography (PPG) must be performed. ) Oxygen saturation can also be measured non-invasively by detecting the signal.

However, since a pressure higher than 1 atmosphere (atm) is created inside the oxygen chamber for high-pressure treatment, the patient's lungs and heart are compressed and their volume decreases, which reduces the ability to deliver oxygen and lowers blood pressure. Conventional blood pressure monitors and oxygen saturation meters developed using indirect measurement methods are set to measure at 1 atmosphere, so there is a problem of measurement errors occurring when measuring in a high pressure environment. In other words, in a high pressure situation, the result value measured non-invasively showed a lower value compared to the result value measured invasively under the same pressure conditions, so there was a risk that the measurement precision and reliability of the result value would decrease. Therefore, there is a need to develop new technologies that can conveniently measure a patient's blood pressure and oxygen saturation during hyperbaric oxygen treatment while increasing measurement precision and reliability.

Public Patent Publication No. 10-2020-0017760 (2020.02.19.) Public Patent Publication No. 10-2015-0071353 (June 26, 2015) Public Patent Publication No. 10-2019-0084093 (2019.07.15.)

The technical idea of the present disclosure is to solve the above-mentioned problems, and its purpose is to provide a technology for measuring a patient's blood pressure and oxygen saturation within an oxygen chamber where high pressure is maintained.

In addition, another purpose of the technical idea of the present disclosure is to provide a technology that can easily measure a patient's blood pressure and oxygen saturation in a high-pressure oxygen chamber while increasing measurement precision and reliability.

The problem to be solved by the present invention is not limited to the above-mentioned problem, and other technical problems not mentioned will be clearly understood by those skilled in the art from the contents described later.

In order to achieve this purpose, in one embodiment of the present invention, a patient monitoring device for an oxygen chamber is used in an oxygen chamber, and the patient monitoring device for an oxygen chamber measures a biosignal of a user located in the oxygen chamber. wealth; and a control unit that adjusts the measurement value measured by the bio-signal measurement unit, wherein the control unit can adjust the measurement value using at least one of pressure information and oxygen concentration information inside the oxygen chamber.

In addition, the biosignal measuring unit includes a blood pressure measuring member that non-invasively measures the blood pressure of the user located in the oxygen chamber to derive a non-invasive blood pressure measurement value, and the patient monitoring device for the oxygen chamber measures the blood pressure of the user located in the oxygen chamber in a non-invasive manner. When a measurement is made, a pressure measuring unit that measures the pressure inside the oxygen chamber and derives a chamber pressure value; It may further include a blood pressure data storage unit in which information on the blood pressure value measured through the blood pressure method under constant pressure conditions is pre-stored.

In addition, the invasive blood pressure value information is the actual blood pressure value measured while inserting a catheter into the blood vessel of the subject and maintaining the pressure inside the oxygen chamber constant, and the invasive blood pressure value information is the pressure inside the oxygen chamber. and actual blood pressure values may be stored as mapped table information in the blood pressure data storage unit.

In addition, the control unit derives a conversion value by adding the chamber pressure value to the non-invasive blood pressure measurement value, checks the invasive blood pressure value measured under the same pressure conditions as the chamber pressure value from the blood pressure data storage unit, and If the difference value obtained by subtracting the conversion value from the intravascular blood pressure value confirmed from the data storage unit is within a predetermined range, the intravascular blood pressure value measured at 760 mmHg is calculated from the table information containing the confirmed intravascular blood pressure value. It can be derived as a blood pressure adjustment value.

In addition, the biosignal measuring unit further includes a photoplethysmographic pulse wave measuring member that measures the photoplethysmographic signal of the user located within the oxygen chamber, and the patient monitoring device for the oxygen chamber is configured to measure the photoplethysmographic pulse wave measuring member. an oxygen measuring unit that measures the oxygen concentration inside the oxygen chamber and derives a chamber oxygen concentration value; and an oxygen saturation data storage unit that pre-stores invasive oxygen saturation information measured invasively under constant oxygen concentration conditions, wherein the control unit may derive a non-invasive oxygen saturation value from the photoplethysmographic signal.

In addition, the invasive oxygen saturation information is the actual oxygen saturation value obtained by collecting arterial blood from the subject while maintaining the oxygen concentration inside the oxygen chamber constant and measuring the oxygen saturation of the collected arterial blood. is table information mapping the oxygen concentration inside the oxygen chamber and the actual oxygen saturation value and may be stored in the oxygen saturation data storage unit.

In addition, the control unit confirms the intravascular oxygen saturation value measured under the same oxygen concentration conditions as the chamber oxygen concentration value from the oxygen saturation data storage unit, and determines the intravascular oxygen saturation value confirmed from the oxygen saturation data storage unit. If the difference value obtained by subtracting the blood oxygen saturation value is within the predetermined range, the intravascular oxygen saturation value measured when the oxygen concentration was 21v/v% is used as oxygen saturation from the table information containing the confirmed intravascular oxygen saturation values. It can be derived as an adjustment value.

Additionally, the controller may derive a heart rate variability value from the photoplethysmographic wave signal.

The means for solving the above problems are merely illustrative and should not be construed as intended to limit the present invention. In addition to the exemplary embodiments described above, there may be additional embodiments described in the drawings and detailed description of the invention.

As described above, according to various embodiments of the present invention, measurement accuracy and reliability of the results are improved by reducing measurement errors that may occur when measuring blood pressure and oxygen saturation in a non-invasive manner in an environment where high pressure is maintained. There are advantages to improving it.

In addition, according to various embodiments of the present invention, the patient's blood pressure and oxygen saturation can be easily measured in a non-invasive manner within a high-pressure oxygen chamber, thereby providing excellent convenience in use.

Effects according to various embodiments of the present invention are not limited to the effects mentioned above, and other effects not mentioned may be clearly understood by those skilled in the art from the description of the claims.

Figure 1 is a block diagram schematically showing a patient monitoring device for an oxygen chamber according to an embodiment of the present invention.
Figure 2 is a conceptual diagram schematically showing the patient monitoring device for an oxygen chamber according to an embodiment of the present invention arranged inside the oxygen chamber.

Preferred embodiments of the present invention will be described in more detail with reference to the attached drawings, but technical parts that are already well-known will be omitted or compressed for brevity of explanation.

It should be noted that references herein to “one” or “one” embodiment of the invention do not necessarily refer to the same embodiment, and they refer to at least one.

In the following examples, singular expressions include plural expressions unless the context clearly indicates a different meaning.

In the following embodiments, terms such as include or have mean that the features or components described in the specification exist, and do not exclude in advance the possibility of adding one or more other features or components.

Since each configuration shown in the drawings is arbitrarily shown for convenience of explanation, the present invention is not necessarily limited to what is shown.

Figure 1 is a block diagram schematically showing a patient monitoring device for an oxygen chamber according to an embodiment of the present invention, and Figure 2 is a block diagram showing a patient monitoring device for an oxygen chamber according to an embodiment of the present invention disposed inside the oxygen chamber. This is a conceptual diagram schematically showing the appearance. Referring to Figures 1 and 2, the patient monitoring device 10 for an oxygen chamber includes a biosignal measurement unit 100, a control unit 200, a pressure measurement unit 300, a blood pressure data storage unit 400, and an oxygen measurement unit. It may include (500) and an oxygen saturation data storage unit (600). In one embodiment, the oxygen chamber 20 is a medical device that accommodates a patient under a pressure environment higher than atmospheric pressure, adds oxygen, and delivers oxygen to the patient's tissues. In one embodiment, the pressure within the oxygen chamber 20 may be maintained in the range of 1 to 6 atm (101 to 607.95 kPa).

The biosignal measurement unit 100 can measure the biosignal of a user located within the oxygen chamber 20. In one embodiment, the biosignal measurement unit 100 may include a blood pressure measurement member 110 and a photoplethysmographic measurement member 120.

The blood pressure measurement member 110 can non-invasively measure the blood pressure of a user located within the oxygen chamber 20 and derive a non-invasive blood pressure measurement value. In one embodiment, the blood pressure measurement member 110 is a non-invasive blood pressure measurement method, so arterial blood pressure can be indirectly measured without making a hole in the artery. For example, the blood pressure measurement member 110 may be implemented using an oscillometric method or a Kortkoff sound method. Specifically, when the blood pressure measurement member 110 is implemented in an oscillometric manner, air pressure is applied to the cuff wrapped around the upper arm, and then the cuff pressure is gradually reduced to reduce the size of pressure oscillation that occurs in the cuff over the arterial blood vessel. The pressure sensor in the blood pressure measuring member 110 can detect and measure systolic blood pressure, diastolic blood pressure, average blood pressure, etc.

In another embodiment, when the blood pressure measurement member 110 is implemented in the Kortkoff sound method, after pressing the cuff on the brachial artery of the arm, the pressure is gradually released and the vascular sound (Cortkoff sound) occurs at the moment when blood flow begins to resume. The patient's blood pressure can be measured by measuring the pressure (systolic pressure) when a Koff sound is heard and the pressure (diastolic pressure) when no sound is heard using a microphone sensor.

The photoplethysmographic measurement member 120 can measure the photoplethysmographic signal of a user located within the oxygen chamber 20. In one embodiment, the photoplethysmographic measurement member 120 may include a photoplethysmographic sensor, and the photoplethysmographic sensor may include a light emitting unit that irradiates light and a light receiving unit that detects the irradiated light. The photoplethysmographic measurement member 120 can calculate a non-invasive oxygen saturation value by amplifying the PPG signal output from the light receiver, removing noise, and converting it into a digital signal.

In addition, in one embodiment, the photoplethysmographic measurement member 120 processes the PPG signal measured from the photoplethysmographic sensor and calculates the time between peaks (Peak to Peak Interval, PPI) in the processed PPG signal. It can be detected. As the heart rate increases, the time between peaks in the PPG signal decreases, while as the heart rate decreases, the time between peaks increases, so the control unit 200 derives the heart rate variability value through PPI analysis in the PPG signal. can do. In one embodiment, it is possible to determine whether claustrophobia occurs due to the interaction between the patient's sympathetic and parasympathetic nerves by monitoring the heart rate variability value. In one embodiment, the heart rate variability value may be implemented as the average heart rate (unit: bpm (beat per minute)) during the recording time.

The control unit 200 may adjust the measurement value measured by the biosignal measurement unit 100. In one embodiment, the control unit 200 may adjust the measured value using at least one of pressure information and oxygen concentration information inside the oxygen chamber 20.

When measurement is made by the blood pressure measuring member 110, the pressure measuring unit 300 can measure the pressure inside the oxygen chamber 20 and derive the chamber pressure value.

The blood pressure data storage unit 400 is a storage device that pre-stores information on blood pressure values measured through blood pressure under constant pressure conditions. In one embodiment, the invasive blood pressure value information is information about the actual blood pressure value measured while a catheter is inserted into the blood vessel of the subject and the pressure inside the oxygen chamber 20 is kept constant. Here, the blood vessels of the subject can be applied as arteries.

Additionally, in one embodiment, the invasive blood pressure value information may be stored in the blood pressure data storage unit 400 as table information in which the pressure inside the oxygen chamber 20 and the actual blood pressure value are mapped. According to one embodiment, after maintaining a specific pressure condition in the oxygen chamber 20 and inserting a catheter into the artery of the subject, the invasive blood pressure value is measured, and the systolic blood pressure and absolute pressure values measured for each pressure are tabulated. It can be created with table information of 1 and stored in the blood pressure data storage unit 400. In Table 1 below, absolute pressure means the sum of chamber internal pressure and systolic blood pressure, and systolic blood pressure and absolute pressure are the actual blood pressure values. In Table 1, systolic blood pressure is gauge pressure, which is the pressure measured with 1 atmosphere (atm) as 0.

chamber internal pressure Systolic blood pressure (mmHg) Absolute pressure (mmHg) 1atm (760mmHg) 120 880 2atm (1520mmHg) 110 1630 3atm (2280mmHg) 100 2380 4atm (3040mmHg) 90 3130

In one embodiment, the control unit 200 derives a conversion value by adding the chamber pressure value to the non-invasive blood pressure measurement value, and checks the invasive blood pressure value measured under the same pressure conditions as the chamber pressure value from the blood pressure data storage unit 400. You can. In addition, if the difference value obtained by subtracting the conversion value from the invasive blood pressure value confirmed from the blood pressure data storage unit 400 is within a predetermined range (for example, greater than 0 and less than 20), the confirmed invasive blood pressure value is included. From the table information, the invasive blood pressure value measured at 760mmHg can be derived as a blood pressure adjustment value.

Hereinafter, the systolic blood pressure of the user located in the oxygen chamber 20 is measured non-invasively to derive a non-invasive blood pressure measurement value, and the non-invasive blood pressure measurement value is adjusted using the pressure information inside the oxygen chamber 20. Explain with an example. However, since this is an exemplary description, the scope of the present invention is not limited to this example.

First, when a patient is in the oxygen chamber 20 and the atmospheric pressure inside the oxygen chamber 20 is maintained at 4 atmospheres (atm), the blood pressure measurement member 110 measures the systolic blood pressure of the upper arm. At this time, the pressure measuring unit 300 measures the pressure inside the oxygen chamber 20 and derives the chamber pressure value as 4 atm (3040 mmHg). If the non-invasive blood pressure measurement value measured by the blood pressure measurement member 110 is 80 mmHg, the control unit 200 derives a conversion value by adding the non-invasive blood pressure measurement value and the chamber pressure value, and the conversion value becomes 3120 mmHg. Afterwards, the control unit 200 searches the table information previously stored in the blood pressure data storage unit 400 and confirms the invasive blood pressure value (absolute pressure) measured at 4 atm (3040 mmHg). When the confirmed invasive blood pressure value is 3130 mmHg, the control unit 200 checks whether the difference value obtained by subtracting 3120 mmHg from 3130 mmHg is within the range of more than 0 and less than 20, and if it is within the range, the value of 760 mmHg stored in the table information is displayed. The blood pressure value is derived as a blood pressure adjustment value. That is, the blood pressure adjustment value derived by the control unit 200 is 880 mmHg in absolute pressure and 120 mmHg in gauge pressure.

Although the above-mentioned example is about the process of deriving systolic blood pressure, diastolic blood pressure can also be implemented in the same way.

Meanwhile, the oxygen measurement unit 500 may measure the oxygen concentration inside the oxygen chamber 20 when measurement is performed by the photoplethysmographic measurement member 120 and derive the chamber oxygen concentration value.

The oxygen saturation data storage unit 600 is a storage device that pre-stores invasive oxygen saturation information measured invasively under constant oxygen concentration conditions. In one embodiment, the vascular oxygen saturation information is information about the actual oxygen saturation value obtained by collecting arterial blood from a subject and measuring the oxygen saturation of the collected arterial blood while keeping the oxygen concentration inside the oxygen chamber 20 constant.

Additionally, in one embodiment, the invasive oxygen saturation information may be stored in the oxygen saturation data storage unit 600 as table information in which the oxygen concentration inside the oxygen chamber 20 and the actual oxygen saturation value are mapped. According to one embodiment, a specific oxygen concentration condition is maintained in the oxygen chamber 20, arterial blood is collected from the subject, a blood gas test is performed, the oxygen saturation of the collected arterial blood is measured, and then the oxygen concentration is measured for each oxygen concentration condition. The oxygen saturation value can be generated as table information in Table 2 and stored in the oxygen saturation data storage unit 600.

Oxygen concentration inside the chamber Vascular oxygen saturation value 21v/v% 98% 23v/v% 95% 24v/v% 93% 25v/v% 91%

In one embodiment, the control unit 200 checks the vascular oxygen saturation value measured under the same oxygen concentration conditions as the chamber oxygen concentration value from the oxygen saturation data storage unit 600, and stores the oxygen saturation value confirmed from the oxygen saturation data storage unit 600. If the difference value obtained by subtracting the non-invasive oxygen saturation value from the invasive oxygen saturation value is within a predetermined range (e.g., greater than 0 to less than 10), the oxygen concentration is calculated from the table information containing the confirmed invasive oxygen saturation value. When is 21v/v%, the measured vascular oxygen saturation value can be derived as the oxygen saturation adjustment value.

Hereinafter, the oxygen saturation value of the user located within the oxygen chamber 20 is measured non-invasively to derive the non-invasive oxygen saturation value, and the non-invasive oxygen saturation value is adjusted using the oxygen concentration information inside the oxygen chamber 20. The process is explained with an example. However, since this is an exemplary description, the scope of the present invention is not limited to this example.

First, when a patient is in the oxygen chamber 20 and the oxygen concentration inside the oxygen chamber 20 is maintained at 25v/v%, the photoplethysmographic pulse wave is measured at the user's fingertip using the photoplethysmographic measurement member 120. Measure. At this time, the oxygen measuring unit 500 measures the oxygen concentration inside the oxygen chamber 20 and derives that the chamber oxygen concentration value is 25v/v%. If the non-invasive oxygen saturation value measured by the photoplethysmographic measurement member 120 is 87%, the control unit 200 queries the table information previously stored in the oxygen saturation data storage unit 600 and determines that the oxygen concentration is 25v/v%. Check the measured oxygen saturation value. When the confirmed vascular oxygen saturation value is 91%, the control unit 200 checks whether the difference value obtained by subtracting 87% from 91% is within the range of more than 0 and less than 10, and if it is within that range, the 21v stored in the table information The invasive oxygen saturation value at /v% is derived as the oxygen saturation adjustment value.

As described above, according to various embodiments of the present invention, measurement precision and reliability of the results are improved by reducing measurement errors that may occur when measuring blood pressure and oxygen saturation in a non-invasive manner in an environment where high pressure is maintained. There is an advantage to this.

In addition, according to various embodiments of the present invention, the patient's blood pressure and oxygen saturation can be easily measured in a non-invasive manner within a high-pressure oxygen chamber, thereby providing excellent convenience in use.

In addition, according to various embodiments of the present invention, biosignal measurement values can be adjusted based on 1 atm (or oxygen concentration of 21 v/v%) even in high pressure situations, and non-invasive measurement values can be adjusted based on the invasive measurement value. Therefore, the effectiveness of coordination can be secured.

As described above, the specific description of the present invention has been made by way of examples with reference to the accompanying drawings, but since the above-described embodiments are only explained by referring to preferred examples of the present invention, the present invention is limited to the above-described embodiments. It should not be understood as being possible, and the scope of rights of the present invention should be understood in terms of the claims described later and their equivalent concepts.

10: Patient monitoring device for oxygen chamber
100: Biosignal measurement unit
110: Absence of blood pressure measurement
120: Photoplethysmographic measurement member
200: control unit
300: Pressure measuring unit
400: Blood pressure data storage unit
500: Oxygen measurement unit
600: Oxygen saturation data storage unit
20: Oxygen chamber

Claims (8)

As a patient monitoring device used within an oxygen chamber,
a bio-signal measurement unit that measures the user's bio-signals located within the oxygen chamber; and
It includes a control unit that adjusts the measurement value measured by the bio-signal measurement unit,
The control unit adjusts the measured value using at least one of pressure information and oxygen concentration information inside the oxygen chamber,
The biosignal measuring unit
It includes a blood pressure measurement member that non-invasively measures the user's blood pressure located within the oxygen chamber and derives a non-invasive blood pressure measurement value,
The patient monitoring device is
a pressure measuring unit that measures the pressure inside the oxygen chamber and derives a chamber pressure value when measurement is performed by the blood pressure measuring member; and
It further includes a blood pressure data storage unit in which information on intravascular blood pressure values measured intravascularly under constant pressure conditions is pre-stored,
The control unit derives a conversion value by adding the chamber pressure value to the non-invasive blood pressure measurement value, checks the invasive blood pressure value measured under the same pressure conditions as the chamber pressure value from the blood pressure data storage unit, and determines the blood pressure data. If the difference value obtained by subtracting the conversion value from the invasive blood pressure value confirmed from the storage unit is within a predetermined range, the invasive blood pressure value measured at 760 mmHg from the table information containing the confirmed invasive blood pressure value is used as blood pressure. Characterized by deriving it as an adjustment value
Patient monitoring device that can be used in a high pressure chamber environment. delete According to paragraph 1,
The invasive blood pressure value information is the actual blood pressure value measured when a catheter is inserted into the blood vessel of the subject and the pressure inside the oxygen chamber is kept constant, and the invasive blood pressure value information is the pressure inside the oxygen chamber and Characterized in that the table information to which actual blood pressure values are mapped is stored in the blood pressure data storage unit.
A patient monitoring device that can be used in a high pressure chamber environment. delete According to paragraph 1,
The biosignal measuring unit
It further includes a photoplethysmography measuring member that measures the photoplethysmographic signal of the user located within the oxygen chamber,
The patient monitoring device that can be used in the high pressure chamber environment is
An oxygen measuring unit that measures the oxygen concentration inside the oxygen chamber and derives a chamber oxygen concentration value when measurement is performed by the photoplethysmographic measurement member; and
It further includes an oxygen saturation data storage unit in which intravascular oxygen saturation information measured intravascularly under constant oxygen concentration conditions is pre-stored,
The control unit is characterized in that it derives a non-invasive oxygen saturation value from the photoplethysmographic signal.
Patient monitoring device that can be used in a high pressure chamber environment. According to clause 5,
The invasive oxygen saturation information is the actual oxygen saturation value obtained by collecting arterial blood from the subject while maintaining the oxygen concentration inside the oxygen chamber constant and measuring the oxygen saturation of the collected arterial blood. The invasive oxygen saturation information is Table information mapping the oxygen concentration inside the oxygen chamber and the actual oxygen saturation value is stored in the oxygen saturation data storage unit.
A patient monitoring device that can be used in a high pressure chamber environment. According to clause 5,
The control unit checks the invasive oxygen saturation value measured under the same oxygen concentration conditions as the chamber oxygen concentration value from the oxygen saturation data storage unit, and determines the non-invasive oxygen saturation value from the invasive oxygen saturation value confirmed from the oxygen saturation data storage unit. If the difference value obtained by subtracting the oxygen saturation value is within the predetermined range, the oxygen saturation is adjusted to the intravascular oxygen saturation value measured when the oxygen concentration is 21v/v% from the table information containing the confirmed intravascular oxygen saturation values. Characterized by deriving it as a value
A patient monitoring device that can be used in a high pressure chamber environment. According to clause 5,
The control unit is characterized in that the heart rate variability value is derived from the photoplethysmographic signal.
A patient monitoring device that can be used in a high pressure chamber environment.

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