KR102578482B1 - Maxillary skeletal expander and manufacturing method thereof - Google Patents

Abstract

The present invention relates to a dental arch expansion device and a method of manufacturing the same. It is a dental arch expansion device that can be printed through 3D printing and adapted to the patient's mouth. It can be used on either the upper or lower jaw, and requires a separate fixing device such as a screw. It can be used without it, so there is no need for separate treatment fixation.
In addition, when using the arch expansion device, compared to the conventional arch expansion device, there is less foreign body sensation and no wounds occur in the oral cavity, so the arch expansion device does not cause pain.

Description

Maxillary skeletal expander and manufacturing method thereof}

The present invention relates to an arch expansion device and a method of manufacturing the same.

In general, uneven dentition, malocclusion, and facial protrusion are caused by the teeth and oral and maxillofacial areas failing to grow properly in place due to maldevelopment of the teeth or jawbone, bad habits or genetics that affect the teeth. The dentition and oral structure serve as factors that determine a person's impression, and cause a decrease in the grinding function of food, so interest in orthodontic treatment is increasing day by day.

However, if the abnormality in the engagement of the upper and lower teeth or the abnormality in the facial skeletal structure is too severe, correction with orthodontic appliances is impossible, and orthodontic treatment such as arch expansion appliances is required.

The arch expansion device is a device used to treat patients whose upper jaw is less developed than the lower jaw, and is a device to facilitate treatment by expanding the upper jaw. The bones of the face are shaped like a puzzle, making it easy to move them during the growth period. The maxilla is also not made up of one bone, but is made up of multiple bones interlocked. If the upper jaw is too small to accommodate permanent teeth, it is possible to widen the arch itself by widening the bone area in the center of the roof of the mouth.

In relation, a conventional arch expansion device includes a pair of main bodies; Expansion screw to adjust the gap between a pair of bodies; Both sides are inserted into a pair of main bodies, and a guide rail is provided to guide the movement of the main bodies; A keyhole formed integrally with the expansion screw; A screw insertion portion that is part of the main body and has a screw insertion hole for guiding the vertical installation of a micro screw to be installed in the upper jaw; An arm that is fixed to the body at one end and extends toward the teeth at the other end; A dental arch expansion device consisting of a tooth fixing part formed integrally with the arm and fixed to the patient's teeth is disclosed.

As described above, in order to expand the dental arch, the main body is fixed to the roof of the mouth through a screw in the upper jaw, and pressure is applied from the main body through an arm extending toward the teeth to expand the left and right widths of the dental arch.

The arch expansion device requires vertical installation through a screw on the roof of the mouth, so when using the arch expansion device, there is a problem of poor aesthetics, and there is a cumbersome problem in that a procedure to install the arch expansion device is required.

In addition, the arch expansion device can be used in the upper jaw, but there is a problem in that it cannot be used in the lower jaw.

Accordingly, there is a need to develop a dental arch expansion device that improves aesthetics, eliminates the need for cumbersome procedures, and allows arch expansion not only in the upper jaw but also in the lower jaw.

(Patent Document 1) KR 10-2226747 B1

The purpose of the present invention relates to a dental arch expansion device, and specifically, to provide a dental arch expansion device that can be printed through 3D printing and adapted to the patient's oral cavity.

Another object of the present invention is to provide a dental arch expansion device that can be used on either the upper or lower jaw and does not require separate surgical fixation because it can be used without a separate fixation device such as a screw.

Another object of the present invention is to provide a dental arch expansion device that causes less foreign body sensation and does not cause pain in the oral cavity compared to conventional arch expansion devices, even when using the arch expansion device, compared to conventional arch expansion devices. .

In order to achieve the above object, the present invention relates to a dental arch expansion device, which includes a fixing part located closely to the upper or lower jaw; And it is coupled to the fixing part and may include an extension formed to contact the boundary between the teeth and the gums.

The fixing part is formed to correspond to the shape of the hard palate and soft palate of the maxilla and is positioned in close contact with the hard palate and the soft palate, and the extension part is formed to contact the boundary between the teeth and gums of the maxilla, and is centered at the center of the fixing part. By being symmetrical in the left and right directions as a standard, force for expansion of the dental arch can be applied.

The fixing part is located in close contact with the floor of the oral cavity under the tongue, and the expansion part is formed to contact the boundary between the lower jaw teeth and the gums, and is symmetrical in the left and right directions with respect to the center of the fixing part, providing strength for expansion of the arch. This can be inflicted.

The expansion unit may further include a dental correction unit for correcting teeth located inside the oral cavity to the outside.

The arch expansion device includes a photocurable oligomer for 3D printing represented by the following formula (1); monomer; photoinitiator; A photocurable composition for 3D printing comprising a stabilizer and a stabilizer, which can be printed using a 3D printer:

[Formula 1]

[Formula 2]

[Formula 3]

[Formula 4]

[Formula 5]

[Formula 6]

here,

n is an integer from 1 to 100,

m is an integer from 1 to 50,

A, B, C and D are the same or different from each other and are each independently a repeating unit selected from the group consisting of compounds represented by Formulas 2 to 6,

a, b, c and d are the same or different from each other and are each independently an integer from 1 to 30,

R ₁ and R ₂ are the same or different from each other, and each independently represents hydrogen, deuterium, a substituted or unsubstituted alkyl group with 1 to 30 carbon atoms, a substituted or unsubstituted alkenyl group with 2 to 30 carbon atoms, or a substituted or unsubstituted carbon number. It may be selected from the group consisting of an alkynyl group having 2 to 30 carbon atoms, a substituted or unsubstituted aryl group having 6 to 30 carbon atoms, and a substituted or unsubstituted heteroaryl group having 1 to 30 carbon atoms.

A method of manufacturing a dental arch expansion device according to another embodiment of the present invention includes obtaining a three-dimensional image of the oral cavity using a 3D scanner; forming a structure for a step-by-step arch expansion device by simulating step-by-step movement for arch expansion using the image using a computer program; And transmitting the step-by-step structure of the arch expansion device obtained through the simulation to a 3D printer to output the arch expansion device, wherein the arch expansion device includes: a fixing part located closely to the upper or lower jaw; And it is coupled to the fixing part and may include an extension formed to contact the boundary between the teeth and the gums.

The fixing part is formed to correspond to the shape of the hard palate and soft palate of the maxilla and is positioned in close contact with the hard palate and the soft palate, and the extension part is formed to contact the boundary between the teeth and gums of the maxilla, and is centered at the center of the fixing part. By being symmetrical in the left and right directions as a standard, force for expansion of the dental arch can be applied.

The fixing part is located in close contact with the floor of the oral cavity under the tongue, and the expansion part is formed to contact the boundary between the lower jaw teeth and the gums, and is symmetrical in the left and right directions with respect to the center of the fixing part, providing strength for expansion of the arch. This can be inflicted.

In the present invention, "substitution" means changing a hydrogen atom bonded to a carbon atom of a compound to another substituent. The position to be substituted is not limited as long as it is the position where the hydrogen atom is substituted, that is, a position where the substituent can be substituted, and if two or more substituents are substituted. , two or more substituents may be the same or different from each other. The substituents include hydrogen, cyano group, nitro group, halogen group, hydroxy group, alkyl group with 1 to 30 carbon atoms, alkenyl group with 2 to 30 carbon atoms, alkynyl group with 2 to 24 carbon atoms, heteroalkyl group with 2 to 30 carbon atoms, and 6 to 6 carbon atoms. Aralkyl group of 30, aryl group of 5 to 30 carbon atoms, heteroaryl group of 2 to 30 carbon atoms, heteroarylalkyl group of 3 to 30 carbon atoms, alkoxy group of 1 to 30 carbon atoms, alkylamino group of 1 to 30 carbon atoms, 6 to 6 carbon atoms Arylamino group of 30, aralkylamino group of 6 to 30 carbon atoms, heteroarylamino group of 2 to 24 carbon atoms, substituted or unsubstituted alkylsilyl group of 1 to 30 carbon atoms, substituted or unsubstituted arylsilyl group of 6 to 30 carbon atoms and substituted Alternatively, it may be substituted with one or more substituents selected from the group consisting of unsubstituted aryloxy groups having 6 to 30 carbon atoms, but is not limited to the above examples.

The present invention is a dental arch expansion device that can be printed through 3D printing and adapted to the patient's oral cavity. It can be used on either the upper or lower jaw, and can be used without a separate fixation device such as a screw, so there is no need for separate fixation for the procedure. not.

In addition, when using the arch expansion device, compared to the conventional arch expansion device, there is less foreign body sensation and no wounds occur in the oral cavity, so the arch expansion device does not cause pain.

1 is a diagram of a dental arch expansion device according to an embodiment of the present invention.
Figure 2 is a diagram of a dental arch expansion device according to an embodiment of the present invention.
Figure 3 is a diagram of a conventional arch expansion device according to an embodiment of the present invention.
Figure 4 is a diagram of a conventional arch expansion device according to an embodiment of the present invention.
Figure 5 shows GPC measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 6 shows NMR measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 7 shows GPC measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 8 shows NMR measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 9 shows GPC measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 10 shows NMR measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 11 shows GPC measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 12 shows NMR measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 13 shows GPC measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 14 shows NMR measurement results for a photocurable oligomer according to an embodiment of the present invention.
Figure 15 is a diagram of a dental arch expansion device according to an embodiment of the present invention.
Figure 16 is an exemplary diagram of the use of the arch expansion device according to one embodiment of the present invention.
Figure 17 is an exemplary diagram of the use of the arch expansion device according to one embodiment of the present invention.

Hereinafter, embodiments of the present invention will be described in detail so that those skilled in the art can easily implement it. However, the present invention may be implemented in many different forms and is not limited to the embodiments described herein.

In the present invention, the dental arch refers to the arch shape in the jaw because the tooth arrangement forms a horseshoe-shaped arch when viewed from the occlusal direction.

In the present invention, arch expansion means expanding the arch by adjusting the angle of the teeth or expanding the basilar bone to the left and right.

In orthodontic treatment, arch expansion treatment has different purposes depending on age. In children and adolescents, arch expansion can improve the skeleton and improve malocclusion, and in adults, arch expansion treatment can be accompanied by orthodontic treatment aimed at restoring dental function and improving appearance due to malocclusion. there is.

The dental arch can be expanded using a conventional wire as shown in Figure 3. As described above, the arch expansion device is a device that expands the narrow dental arch, and can be mainly used in the upper jaw. In addition, it is not just about opening the teeth; the bones of the arch must be sorted out.

Conventional arch expansion devices not only use wires as shown in Figure 3, but are also commonly used as shown in Figure 4 with a part that is fixed to the roof of the mouth using a screw and an arm for applying force from the screw to the teeth. there is.

In the case of arch expansion devices that use only wires or fix the main body to the roof of the mouth with screws as described above, although they can exert sufficient force to expand the arch, there are cases where excessive force is applied to the roof of the mouth and injuries occur. Also, when the tongue must touch the roof of the mouth when swallowing or speaking, excessive foreign body sensation occurs, causing great discomfort to the patient.

Therefore, in the present invention, like the conventional arch expansion device, it can be used without a separate fixing device such as a screw, so there is no need for a separate surgical fixation. It is characterized by being able to

Specifically, a fixation unit located closely to the upper or lower jaw; And it is coupled to the fixing part and may include an extension formed to contact the boundary between the teeth and the gums.

Figure 1 relates to an arch expansion device 100 according to an embodiment of the present invention, and specifically relates to an example of the arch expansion device 100 used in the upper jaw. The fixing part 200 is formed to correspond to the shape of the hard palate and soft palate of the maxilla and can be positioned in close contact with the hard palate and the soft palate, and the extension part 300 is formed to contact the boundary between the teeth and gums of the maxilla. and is symmetrical in the left and right directions based on the center of the fixing part, so that a force for expansion of the dental arch can be applied.

As shown in FIG. 3, the conventional arch expansion device combines the device by coupling a wire to a tooth, and can also exhibit force to expand the dental arch. Alternatively, a method of fixing the main body to the upper jaw using screws was used.

In the case of the present invention, as shown in FIG. 1, even though there is no separate fixing device, it is adhered closely to the roof of the mouth and does not fall off easily, and can exhibit the effect of expanding the dental arch.

Specifically, the fixing part 200 is output to correspond to the shape of the hard palate and the soft palate of the maxilla, so that it can be completely adhered to when used. The upper jaw is usually arch-shaped and has a hollow shape inside, as if a groove is formed. Accordingly, the fixing part 200 printed using a 3D printer may also have a corresponding shape.

The fixing part 200 is designed to prevent the arch expansion device of the present invention from easily falling out when used together with the expansion part 300, and unlike conventional arch expansion devices, it has a shape corresponding to the roof of the mouth to reduce the feeling of a foreign body. You can.

In addition, the extension part 300 is formed to contact the boundary between the teeth and the gums, and is used in close contact with the patient's gums.

As described later, the arch expansion device 100 of the present invention captures the patient's oral condition as a video image through a 3D scanner, and when the shape of the arch expansion device is derived in stages through a computer program, It can be printed in the correct format.

In other words, the output dental arch expansion device 100 is output in a form that corresponds to the shape of the dental arch expanded more than the current patient's dental arch.

As described above, the arch expansion device 100 printed in the form of the patient's expanded dental arch at each stage may not be easily adhered to the patient's upper jaw if it is intended to be attached to the patient's upper jaw.

That is, the arch expansion device 100 of the present invention is in complete contact with the patient's upper or lower jaw, and specifically, is tightly coupled to the border between the teeth and gums. In a state of close contact, the arch expansion device 100 is currently As it is output in a form larger than the patient's dental arch, the arch expansion device 100 of the present invention can be expanded by a force that expands it to the outside based on the central point.

In order to enable arch expansion using the arch expansion device 100 of the present invention as described above, it is very important to place it closely to the patient's upper or lower jaw.

The above features will be described later.

Figure 2 is an example of an arch expansion device 100 according to an embodiment of the present invention that can be used on the lower jaw.

The lower jaw is used for the lower tongue, and the shapes of the arch expansion device 100 and the fixing parts 200 and 200' used for the upper jaw are different.

There are parts under the tongue, such as the lingual frenulum and sublingual gland, where the fixing part 200' of the present invention cannot be located, so the fixing part 200' is located in a part other than the corresponding part.

However, the expansion part 300', like the arch expansion device 100 used in the upper jaw, is formed to contact the boundary between the lower jaw teeth and the gums, and is symmetrical in the left and right directions with respect to the center of the fixing part, A force for expansion may be applied.

Additionally, the arch expansion device 100 of the present invention may additionally include a tooth correction unit (not shown). The orthodontic part (not shown) may be extended and coupled to the expansion part in order to correct teeth located inside the oral cavity outward.

In general, the extension parts (300, 300') of the present invention are formed to contact the boundary portion of the teeth and gums, and the force applied to the upper or lower jaw by the extension parts (300, 300') is applied to the teeth and gums. Make sure it only extends to the border area.

This means that when a pushing force is generated to the tooth portion, the force is not applied to the entire tooth but only to a part of the tooth, which may cause the problem of the teeth being tilted.

That is, the arch expansion device 100 of the present invention is intended to expand the dental arch, and only the effect of expanding the upper or lower jaw is intended to be exerted, and the teeth are tilted by the arch expansion device 100 of the present invention. This should not happen.

In order to prevent the teeth from being tilted as described above, the arch expansion device 100 of the present invention may be formed so that the expansion portions 300 and 300' are in contact with the boundary between the teeth and the gums.

In general, teeth are divided into a crown, a tooth neck, and a tooth root. The crown is the visible upper part of the tooth, the tooth root is the root part of the tooth, and the cervical region refers to the boundary between the tooth and the gums described above.

In order to move the entire tooth by external force, it is important that force is applied to the center of the tooth, and in this case, the center of the tooth corresponds to the cervical region. In other words, if the pushing force acts only on the gum area toward the root of the tooth, the pushing force may not be applied smoothly to the tooth, and if the pushing force acts on the crown side, the tilting phenomenon of the tooth may occur. Accordingly, in the present invention, the arch expansion device 100 can provide a dental arch expansion effect and prevent teeth tilting.

However, depending on the patient's dental structure, if some of the teeth are tilted inward or the teeth protrude inward, it may be necessary to move them to the outside of the oral cavity.

That is, in a case where the space between teeth is very narrow and the teeth are positioned unevenly, some teeth may be located inside the teeth or may be tilted toward the inside of the oral cavity.

In this case, conventionally, an arch expansion device was used to widen the gap between teeth, and an orthodontic device was used to adjust the positions of the teeth so that they were evenly arranged.

On the other hand, as described above, the arch expansion device 100 of the present invention converts the patient's oral condition into image data using a 3D scanner and outputs it to the arch expansion device 100 in stages through a computer program. As previously explained, if it is necessary to simultaneously push and position some of the patient's teeth to the outside, an orthodontic section (not shown) is formed in succession to the expansion sections 300 and 300' to expand the arch and expand the teeth. The correction effect can occur simultaneously.

As described above, the arch expansion device 100 must be located closely to the patient's upper or lower jaw and be able to exert expansion force. In order to work this way, it must be able to fit completely against the patient's upper or lower jaw.

Accordingly, the present invention is characterized in that the arch expansion device 100 is printed using a 3D printer using a shape memory polymer.

When the arch expansion device 100 is immersed in water above 40°C before use, it becomes flexible and can be transformed into a shape that fits the patient's upper or lower jaw.

Conventionally, the hard plastic material used to manufacture transparent orthodontic devices can exert sufficient force to expand the dental arch when used as an arch expansion device, but there is a problem in that it is difficult to completely adhere to the patient's upper or lower jaw for use. In other words, in order to attach it to the upper or lower jaw of a patient who has not yet expanded in a state that is manufactured in a form suitable for the arch that has been expanded step by step, the arch expansion device must be bent and used, but if force is applied to bend it, it may break. Even if it is inserted in a bent state, it is impossible to use it completely tightly.

On the other hand, the arch expansion device 100 of the present invention is printed using a photocurable polymer composition for a 3D printer, which will be described later, and when immersed in water above 40°C, it becomes flexible and can be changed in shape, causing pain to the patient. It can be completely adhered to the upper or lower jaw that needs expansion without doing so.

When the arch expansion device 100 of the present invention is used on a patient, it is immersed in water of 40°C or higher. At this time, it is deformed into a shape tailored to the patient's arch, but is gradually restored to its original shape by body temperature, and at this time, the restoring force This generates a pushing force on the upper or lower jaw, allowing the dental arch to expand.

The photocurable polymer composition for 3D printers includes a photocurable oligomer for 3D printing represented by the following formula (1); monomer; photoinitiator; and stabilizers:

[Formula 1]

[Formula 2]

[Formula 3]

[Formula 4]

[Formula 5]

[Formula 6]

here,

n is an integer from 1 to 100,

m is an integer from 1 to 50,

A, B, C and D are the same or different from each other and are each independently a repeating unit selected from the group consisting of compounds represented by Formulas 2 to 6,

a, b, c and d are the same or different from each other and are each independently an integer from 1 to 30,

R ₁ and R ₂ are the same or different from each other, and each independently represents hydrogen, deuterium, a substituted or unsubstituted alkyl group with 1 to 30 carbon atoms, a substituted or unsubstituted alkenyl group with 2 to 30 carbon atoms, or a substituted or unsubstituted carbon number. It may be selected from the group consisting of an alkynyl group having 2 to 30 carbon atoms, a substituted or unsubstituted aryl group having 6 to 30 carbon atoms, and a substituted or unsubstituted heteroaryl group having 1 to 30 carbon atoms.

The photocurable oligomer includes a urethane acrylate structure as a main chain, a photocurable functional group is bonded to the urethane structure, and the compound is characterized by including soft functional groups and hard functional groups.

The printed product exhibits flexible properties due to the soft functional groups included in the photocurable composition, and can also exhibit heat resistance due to the hard functional groups.

In other words, by combining a photocurable functional group with a photocurable oligomer and using a soft functional group and a hard functional group, not only can a flexible effect be achieved by using a carbon skeleton that has soft properties at room temperature, but also hard properties can be achieved at room temperature. By using the carbon skeleton it has, it can exhibit heat-resistant properties.

As the photocurable oligomer contains a carbon skeleton with hard properties, it has excellent physical properties such as thermal properties, strength, elastic modulus, and tensile elongation, and can produce 3D printing outputs that can be restored to their original shape by heat. there is.

In addition, since the photocurable oligomer contains a carbon skeleton with soft properties, its shape can be modified by external force after heat is provided.

Generally, a composition for a 3D printer includes, as described below, a photocurable oligomer for 3D printing; monomer; photoinitiator; and a stabilizer. Oligomers, monomers, photoinitiators, and stabilizers included in the composition all affect the physical properties of the output, but oligomers have the greatest influence. Accordingly, in general, in order to increase the physical properties of 3D printed products, only carbon skeletons with hard properties are included, which can increase the physical properties of the printed product, but on the contrary, when the shape is deformed by use, the shape is restored. Since this is not possible, there is a problem in that it cannot be used multiple times.

The composition for a 3D printer in the present invention contains a carbon skeleton with hard properties and a carbon skeleton with soft properties, so it not only has excellent physical properties such as thermal properties, strength, elastic modulus, and tensile elongation, but also has a soft functional group. The flexible nature of can be used together, so if the shape is changed by an external force while heat is provided, the deformed shape can be fixed, and then when heat is provided again, it can be restored to the original shape.

A, B, and D may be the same or different from each other, and may each independently be a repeating unit selected from a compound represented by Formula 2 or 3.

The C may be a repeating unit selected from the group consisting of compounds represented by Formulas 4 to 6.

Specifically, the photocurable oligomer represented by Formula 1 may be produced by a method of synthesizing urethane acrylate series. Basically, it proceeds through a stepwise polymerization reaction of diol and diisocyanate, and to prevent gelation of the material as the molecular weight increases during the polymerization process, an acrylic monomer without a reaction site was used as a suspension. The monomers used in the synthesis of the oligomer of the present invention as usable acrylic monomers may be Isobornyl acrylate, Cyclic Trimethylolpropane Formal Acrylate, Lauryl acrylate, Lauryl methacrylate, 3,5,3-trimethelhexyl acrylate, Tetrahydrofurfuryl acrylate, Tetrahydrofurfuryl methacrylate, Benzyl methacrylate, etc. .

More specifically, diol was pre-added to the monomer base used as a monomer to stabilize it, and then diisocyanate was added. As the urethane reaction progressed, reaction heat was generated, the urethane chain became longer, and the molecular weight increased.

As molecular weight increases, the viscosity of the material may also increase. When the above molecular weight increase occurs rapidly, the temperature rises rapidly, which causes the urethane reaction to also proceed more rapidly. As a result, the oligomer gels before reaching a sufficient molecular weight, making it impossible to use as a material. The sun sets. Therefore, in the present invention, in order to prevent this reaction, as a solvent for adding diol, Isobornyl acrylate, Cyclic Trimethylolpropane Formal Acrylate, Lauryl acrylate, Lauryl methacrylate, 3,5,3-trimethelhexyl acrylate, Tetrahydrofurfuryl acrylate, Tetrahydrofurfuryl methacrylate, Benzyl A methacrylate selected from the group consisting of methacrylate and mixtures thereof was used. The solvent does not participate in the reaction and is used to control the reaction rate of the material and prevent a rapid increase in viscosity due to an increase in molecular weight. In addition, monomers for synthesizing the oligomer of the present invention must not have functional groups capable of urethane reaction, such as hydroxyl groups or urethane groups. Through the above conditions, the present invention will enable the production of oligomers with excellent mass production and process stability.

In addition, the equivalence ratio between diol and diisocyanate was set to a state where the equivalent weight of diisocyanate was higher than that of diol, leading to the presence of an isocyanate group at the end of the oligomer. During the reaction process, a reaction catalyst including a Zn-based catalyst can be used. The catalyst may or may not be included. The catalyst is included to make the reaction proceed more quickly, and the reaction can proceed even if it is not necessarily included. However, even if it is included, the reaction can proceed with a very small amount.

After the temperature increase was stopped due to the completion of the urethane reaction, 2-hydroxy acrylate and 2-hydroxy methacrylate were added through a drop method to end cap the ends of the oligomer.

The diols used for the preparation of the oligomers are as follows:

Additionally, the diisocyanate for reaction with the diol is as follows:

Additionally, monomers that may be included to terminate the urethane reaction or increase the molecular weight are as follows:

The compound represented by Formula 1 prepared by the above production method may be selected from the group consisting of the following compounds:

The photocurable oligomer may have a number average molecular weight (Mn) of 1,500 to 6,000, 1,500 to 5,500, or 1,600 to 5,000. The photocurable oligomer may have a weight average molecular weight (Mw) of 2,500 to 9,000, 3,000 to 8,500, or 3,500 to 8,000.

Using an oligomer having a number average molecular weight and a weight average molecular weight within the above range, a photocurable composition for 3D printing described later is prepared, and using this, a dental arch expansion device customized to the patient's oral structure is printed and used. This can increase the patient's convenience of use and increase the effect of arch expansion. Specifically, the arch expansion device of the present invention changes into a deformed shape when immersed in water at 50 to 100°C and then deformed, but when it is used while inserted into the upper or lower jaw, the shape changes due to body temperature. The changed arch expansion device can gradually be restored to its original shape, showing the arch expansion effect.

As described above, when various oligomers are selected according to the physical properties such as tensile strength, flexural strength, flexural elasticity, and flexural strength required for each product, and use them to manufacture a photocurable composition for 3D printing, they are characterized as shape memory polymers. It can be provided as a patient-tailored arch expansion device.

The photocurable oligomer may have a viscosity of 2,000 psi to 3,500 psi, 2,100 psi to 3,200 psi, and 2,200 psi to 3,000 psi. When manufacturing a photocurable composition using an oligomer having a viscosity in the above range, it can be provided at a viscosity suitable for use in a 3D printer.

The photoinitiator may be BP, TPO, DCP, BPO, DPPO, etc., but is preferably DPPO (2-hydroxy-2-methylpropiophenone). However, it is not limited to the above example, and a photocurable composition can be prepared. All photoinitiators available can be used without restrictions.

The stabilizer may be selected from the group consisting of tertiary amines such as diethylethanolamine and trihexylamine, hindered amines, organic phosphates, and hindered phenols, but is not limited to the above examples and can be used to prepare a photocurable composition. Any stabilizer that can be used can be used without restrictions.

In addition to the photoinitiator and stabilizer, other additives may be additionally included.

The additives may include conventional additives such as leveling agents, slip agents, or stabilizers to improve thermal and oxidation stability, storage stability, surface properties, flow properties, and process properties.

The photocurable composition according to an embodiment of the present invention may include 1 part by weight of a photoinitiator based on 100 parts by weight of UV resin. The UV resin is a photocurable oligomer of the present invention; and monomers, and more specifically, a compound represented by Formula 1 below, a compound represented by Formula 7 below, and a compound represented by Formula 8 below at a weight ratio of 1:1:1 to 2:1:1. can do.

A method of manufacturing a dental arch expansion device according to another embodiment of the present invention includes obtaining a three-dimensional image of the oral cavity using a 3D scanner; forming a structure for a step-by-step arch expansion device by simulating step-by-step movement for arch expansion using the image using a computer program; And transmitting the step-by-step structure of the arch expansion device obtained through the simulation to a 3D printer to output the arch expansion device, wherein the arch expansion device includes: a fixing part located closely to the upper or lower jaw; And it is coupled to the fixing part and may include an extension formed to contact the boundary between the teeth and the gums.

The computer program uses a commercially available program, provides step-by-step expansion of the dental arch, and can derive the structure of an arch expansion device appropriate for the arch expansion.

The structural information about the arch expansion device derived above can be transmitted to a 3D printer and used to print the arch expansion device of the present invention.

The arch expansion device according to an embodiment of the present invention may be output in the shape shown in FIG. 15. FIG. 15 illustrates an embodiment of the arch expansion device of the present invention for use in the upper jaw.

As shown in Figure 16, it can be used in complete contact with the roof of the mouth and can be positioned to contact the boundary between teeth and gums. As described above, the dental arch expansion device can demonstrate the expansion effect of the dental arch step by step by using the characteristics of the shape memory polymer.

Additionally, the arch expansion device of the present invention can be used with a transparent orthodontic device. As shown in Figure 17, by using a transparent orthodontic device together, the shape of the teeth can be prevented from being deformed during the expansion of the dental arch, and teeth can be straightened at the same time as the arch is expanded.

It is possible to use the device in the state of use as shown in FIG. 17 because the arch expansion device of the present invention acquires information about the patient's oral cavity using a 3D scanner and is custom-made using a 3D printer.

Manufacturing Example 1

Manufacturing of photocurable oligomers for 3D printing

Isobornyl acrylate was used as a solvent, polypropylene glycol, cyclohexanedimethanol, and BHT were added and stirred at 10 to 50°C at 10 to 200 rpm, and isophorone diisocyanate was added. was added and stirred by changing the stirring speed from 50 to 200 rpm under the same temperature conditions. Afterwards, HEMA was added and stirred at 150 to 500 rpm at 50 to 250°C to prepare an oligomer.

The intermediate compounds produced by the above reaction are as follows:

The intermediate compound was reacted with the following monomers:

The oligomer finally produced by reacting the intermediate compound is as follows:

The GPC analysis results for the oligomer of Preparation Example 1 are shown in Figure 5. Additionally, the NMR analysis results are shown in Figure 6.

Production example 2

Oligomers were prepared in the same manner as in Preparation Example 1, but the monomers used were different during the reaction. The oligomers prepared were as follows:

The GPC analysis results for the oligomer of Preparation Example 2 are shown in Figure 7. Additionally, the NMR analysis results are shown in Figure 8.

Production example 3

Oligomers were prepared in the same manner as in Preparation Example 1, but the monomers used were different during the reaction. The oligomers prepared were as follows:

The GPC analysis results for the oligomer of Preparation Example 3 are shown in Figure 9. Additionally, the NMR analysis results are shown in Figure 10.

Production example 4

Oligomers were prepared in the same manner as in Preparation Example 1, but the monomers used were different during the reaction. The oligomers prepared were as follows:

The GPC analysis results for the oligomer of Preparation Example 4 are shown in Figure 11. Additionally, the NMR analysis results are shown in Figure 12.

Production example 5

Oligomers were prepared in the same manner as in Preparation Example 1, but the monomers used were different during the reaction. The oligomers prepared were as follows:

The GPC analysis results for the oligomer of Preparation Example 5 are shown in Figure 13. Additionally, the NMR analysis results are shown in Figure 14.

The results of the analysis of the oligomers of Preparation Examples 1 to 5 are summarized in Table 1 below:

Manufacturing Example 1 Production example 2 Production example 3 Production example 4 Production example 5 GPC Mn 4179 4102 1663 4767 2691 Mw 6944 6763 7855 7591 3703 PDI 1.68 1.65 1.68 1.59 1.38 NMR A
(6.44) O O O O O B
(5.89) O O O O O C
(5.61) O
(39.0) O
(39.3) O
(9.3) O
(22.1) X D
(4.91) O
(87.9) O
(89.6) O
(77.6) O
(86.4) O
(61.0) E
(6.48) X X O
(16.1) X O
(22.3) F(6.49) X X O X O G(3.41) O O O O O

Experimental Example 1

Check physical properties

The viscosity of the oligomers of Preparation Examples 1 to 5 was measured, and the mechanical properties were measured after 3D printing.

In order to measure mechanical properties, the oligomers of Preparation Examples 1 to 5, the compound represented by Formula 7 below, and the compound represented by Formula 8 below were mixed at a weight ratio of 1:1:1, and 100 parts by weight of the mixture was added. 1 part by weight of DPPO was mixed to prepare a polymer composition, which was placed in a 3D printer and prepared as a specimen:

[Formula 7]

[Formula 8]

Specifically, flexural strength was conducted according to ISO 20795-2 and ISO 10477 standards, and tensile strength was conducted according to ASTM D638.

Manufacturing Example 1 Production example 2 Production example 3 Production example 4 Production example 5 Batch Size 50L 50L 50L 50L 50L blending and
3D
printing output
After mechanical properties Flexural strength
(20795-2 specimen, MPa) 171 162 155 163 150 Flexural elasticity
(20795-2 specimen, MPa) 3939 3807 3800 3655 3594 Flexural strength (10477 specimen, MPa) 146 122 162 158 143 Tensile strength (D 638, MPa) 109 102 115 113 108 Elongation (D 638, %) 3.9 3.0 7.6 6.5 7.7 Viscosity (psi) 2880 2950 2220 2380 2380

It was confirmed that the specimens prepared using the oligomers of Preparation Examples 1 to 5 showed excellent mechanical properties, and that they could be printed using a 3D printer through appropriate viscosity.

However, in order to show the arch expansion effect, the flexural strength must be 150 MPa or more and the tensile strength must be 110 MPa or more, so the photocurable composition using the oligomers of Preparation Examples 3 and 4 can be used as an arch expansion device. , In the case of other manufacturing examples, when used as a dental arch expansion device, the arch expansion effect due to shape deformation may be insufficient.

Experimental Example 2

Manufacture of arch expansion device

The polymer composition prepared by mixing the oligomer, monomer, and photoinitiator of Experimental Example 1 was put into a 3D printer and printed with a dental arch expansion device.

To confirm the shape memory properties, an experiment was conducted on deformation and shape restoration due to heat.

The test method is to change the shape by applying an external force after immersing it in water at 50 to 100°C, determine whether the deformed form is fixed, and immerse the deformed shape in water between 40 to 80°C and then change the shape to 20 to 30°C. It was confirmed whether it could be restored to its original form.

After first immersing in water at 40 to 80℃, the shape is deformed by external force and the deformed shape is fixed, and then after immersing in water at 50 to 100℃ and the shape is restored to its original state at 20 to 30℃, it is marked as O. indicated.

Manufacturing example 1 Production example 2 Production example 3 Production example 4 Production example 5 shape memory properties O O O O O

According to Table 3 above, after putting it in the hot water temperature (50 to 70°C) of a water purifier that is generally easily accessible, it was possible to deform the shape and fix it in the deformed form, and then put it in water at a warm water temperature and apply an external force. It was confirmed that if no action was taken, it would be restored to its original form.

Using the above shape memory characteristics, when manufacturing a dental arch expansion device and inserting it into the patient's upper or lower jaw, it is placed in warm water and used in a flexible state, allowing the patient to completely adhere to the upper or lower jaw without feeling much pain. It can be inserted. Afterwards, the shape is gradually transformed to its original form by body temperature, and the circular shape corresponds to the state of the upper or lower jaw expanded in stages by a computer program as described above, and a pushing force is applied to expand the dental arch. It can be effective.

Although the preferred embodiments of the present invention have been described in detail above, the scope of the present invention is not limited thereto, and various modifications and improvements made by those skilled in the art using the basic concept of the present invention defined in the following claims are also possible. falls within the scope of rights.

Claims (8)

An anchor located closely to the upper or lower jaw; and
A dental arch expansion device that is coupled to the fixture and includes an expansion portion formed to contact the boundary between teeth and gums,
The arch expansion device includes a photocurable oligomer for 3D printing represented by the following formula (1);
monomer;
photoinitiator; and
A photocurable composition for 3D printing containing a stabilizer, printed using a 3D printer.
Arch expansion device:
[Formula 1]

[Formula 2]

[Formula 3]

[Formula 4]

[Formula 5]

[Formula 6]

here,
n is an integer from 1 to 100,
m is an integer from 1 to 50,
A, B, C and D are the same or different from each other and are each independently repeating units selected from the group consisting of compounds represented by formulas 2 to 6,
a, b, c and d are the same or different from each other and are each independently an integer from 1 to 30,
R ₁ and R ₂ are the same or different from each other, and each independently represents hydrogen, deuterium, a substituted or unsubstituted alkyl group having 1 to 30 carbon atoms, a substituted or unsubstituted alkenyl group having 2 to 30 carbon atoms, or a substituted or unsubstituted carbon number. It may be selected from the group consisting of an alkynyl group of 2 to 30 carbon atoms, a substituted or unsubstituted aryl group of 6 to 30 carbon atoms, and a substituted or unsubstituted heteroaryl group of 1 to 30 carbon atoms. According to paragraph 1,
The fixing part is formed to correspond to the shape of the hard palate and soft palate of the maxilla and is positioned in close contact with the hard palate and soft palate,
The expansion part is formed to contact the boundary between the maxillary teeth and the gums, and is symmetrical in the left and right directions with respect to the center of the fixation part, so that a force for expansion of the arch is applied.
Arch expansion device. According to paragraph 1,
The fixing part is located in close contact with the floor of the mouth under the tongue,
The expansion part is formed to contact the boundary between the lower jaw teeth and the gums, and is symmetrical in the left and right directions with respect to the center of the fixation part, so that a force for expansion of the arch is applied.
Arch expansion device. According to paragraph 1,
The expansion unit further includes a dental correction unit for correcting teeth located inside the oral cavity to the outside.
Arch expansion device. delete Obtaining a three-dimensional image of the oral cavity using a 3D scanner;
forming a structure for a step-by-step arch expansion device by simulating step-by-step movement for arch expansion using the image using a computer program; and
A step of transmitting the structure of the step-by-step arch expansion device obtained through the simulation to a 3D printer to print the arch expansion device,
The arch expansion device includes a fixing part located closely to the upper or lower jaw; and
It is coupled to the fixing part and includes an extension formed to contact the boundary between the teeth and the gums,
The arch expansion device includes a photocurable oligomer for 3D printing represented by the following formula (1);
monomer;
photoinitiator; and
A photocurable composition for 3D printing containing a stabilizer, printed using a 3D printer.
Method of manufacturing the arch expansion device:
[Formula 1]

[Formula 2]

[Formula 3]

[Formula 4]

[Formula 5]

[Formula 6]

here,
n is an integer from 1 to 100,
m is an integer from 1 to 50,
A, B, C and D are the same or different from each other and are each independently repeating units selected from the group consisting of compounds represented by formulas 2 to 6,
a, b, c and d are the same or different from each other and are each independently an integer from 1 to 30,
R ₁ and R ₂ are the same or different from each other, and each independently represents hydrogen, deuterium, a substituted or unsubstituted alkyl group having 1 to 30 carbon atoms, a substituted or unsubstituted alkenyl group having 2 to 30 carbon atoms, or a substituted or unsubstituted carbon number. It may be selected from the group consisting of an alkynyl group of 2 to 30 carbon atoms, a substituted or unsubstituted aryl group of 6 to 30 carbon atoms, and a substituted or unsubstituted heteroaryl group of 1 to 30 carbon atoms. According to clause 6,
The fixing part is formed to correspond to the shape of the hard palate and soft palate of the maxilla and is positioned in close contact with the hard palate and soft palate,
The expansion part is formed to contact the boundary between the maxillary teeth and the gums, and is symmetrical in the left and right directions with respect to the center of the fixation part, so that a force for expansion of the arch is applied.
Method of manufacturing an arch expansion device. According to clause 6,
The fixing part is located in close contact with the floor of the mouth under the tongue,
The expansion part is formed to contact the boundary between the lower jaw teeth and the gums, and is symmetrical in the left and right directions with respect to the center of the fixation part, so that a force for expansion of the arch is applied.
Method of manufacturing an arch expansion device.