KR102527953B9 - Microorganism expressing heterologous protein and use thereof - Google Patents

Microorganism expressing heterologous protein and use thereof

Info

Publication number
KR102527953B9
KR102527953B9 KR1020220047195A KR20220047195A KR102527953B9 KR 102527953 B9 KR102527953 B9 KR 102527953B9 KR 1020220047195 A KR1020220047195 A KR 1020220047195A KR 20220047195 A KR20220047195 A KR 20220047195A KR 102527953 B9 KR102527953 B9 KR 102527953B9
Authority
KR
South Korea
Prior art keywords
heterologous protein
expressing heterologous
microorganism expressing
microorganism
protein
Prior art date
Application number
KR1020220047195A
Other languages
Korean (ko)
Other versions
KR20220050869A (en
KR102527953B1 (en
Inventor
송지윤
노현진
정이레
김영현
조승기
Original Assignee
주식회사 리비옴
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020210040065A external-priority patent/KR102635553B1/en
Application filed by 주식회사 리비옴 filed Critical 주식회사 리비옴
Priority to KR1020220047195A priority Critical patent/KR102527953B1/en
Publication of KR20220050869A publication Critical patent/KR20220050869A/en
Application granted granted Critical
Publication of KR102527953B1 publication Critical patent/KR102527953B1/en
Publication of KR102527953B9 publication Critical patent/KR102527953B9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020220047195A 2021-03-29 2022-04-15 Microorganism expressing heterologous protein, and use thereof KR102527953B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020220047195A KR102527953B1 (en) 2021-03-29 2022-04-15 Microorganism expressing heterologous protein, and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020210040065A KR102635553B1 (en) 2018-12-28 2021-03-29 Microorganism expressing heterologous protein, and use thereof
KR1020220047195A KR102527953B1 (en) 2021-03-29 2022-04-15 Microorganism expressing heterologous protein, and use thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020210040065A Division KR102635553B1 (en) 2018-12-28 2021-03-29 Microorganism expressing heterologous protein, and use thereof

Publications (3)

Publication Number Publication Date
KR20220050869A KR20220050869A (en) 2022-04-25
KR102527953B1 KR102527953B1 (en) 2023-05-03
KR102527953B9 true KR102527953B9 (en) 2023-09-07

Family

ID=75444111

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020220047195A KR102527953B1 (en) 2021-03-29 2022-04-15 Microorganism expressing heterologous protein, and use thereof
KR1020220047194A KR102527954B1 (en) 2021-03-29 2022-04-15 Microorganism expressing heterologous protein, and use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020220047194A KR102527954B1 (en) 2021-03-29 2022-04-15 Microorganism expressing heterologous protein, and use thereof

Country Status (1)

Country Link
KR (2) KR102527953B1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU682638B2 (en) * 1995-06-09 1997-10-09 ILS, Inc. Peptide, bronchodilator and blood flow ameliorant
US6849714B1 (en) * 1999-05-17 2005-02-01 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
WO2011148219A1 (en) * 2010-05-28 2011-12-01 Compagnie Gervais Danone Probiotic strains for use in improving the enteric nervous system
CN108753670A (en) * 2018-05-28 2018-11-06 西北工业大学 Multi-functional compound micro-ecological preparation nanometer selenium-recombinant expression vasoactive intestinal peptide-Lactococcus lactis and preparation method

Also Published As

Publication number Publication date
KR20220050869A (en) 2022-04-25
KR102527954B9 (en) 2023-09-07
KR102527954B1 (en) 2023-05-03
KR20220050124A (en) 2022-04-22
KR102527953B1 (en) 2023-05-03

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Legal Events

Date Code Title Description
A107 Divisional application of patent
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
G170 Re-publication after modification of scope of protection [patent]