KR102518750B9 - Phosphatase that modulates melanin production of Cryptococcus neoformans and method for screening antifungal agents using the same - Google Patents

Phosphatase that modulates melanin production of Cryptococcus neoformans and method for screening antifungal agents using the same

Info

Publication number
KR102518750B9
KR102518750B9 KR1020210042531A KR20210042531A KR102518750B9 KR 102518750 B9 KR102518750 B9 KR 102518750B9 KR 1020210042531 A KR1020210042531 A KR 1020210042531A KR 20210042531 A KR20210042531 A KR 20210042531A KR 102518750 B9 KR102518750 B9 KR 102518750B9
Authority
KR
South Korea
Prior art keywords
phosphatase
same
antifungal agents
melanin production
cryptococcus neoformans
Prior art date
Application number
KR1020210042531A
Other languages
Korean (ko)
Other versions
KR102518750B1 (en
KR20210137381A (en
Inventor
반용선
정은지
진재형
이경태
이동기
김진영
이승헌
홍주현
Original Assignee
연세대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 연세대학교 산학협력단 filed Critical 연세대학교 산학협력단
Publication of KR20210137381A publication Critical patent/KR20210137381A/en
Application granted granted Critical
Publication of KR102518750B1 publication Critical patent/KR102518750B1/en
Publication of KR102518750B9 publication Critical patent/KR102518750B9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020210042531A 2020-05-08 2021-04-01 Phosphatase that modulates melanin production of Cryptococcus neoformans, and method for screening antifungal agents using the same KR102518750B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20200055355 2020-05-08
KR1020200055355 2020-05-08

Publications (3)

Publication Number Publication Date
KR20210137381A KR20210137381A (en) 2021-11-17
KR102518750B1 KR102518750B1 (en) 2023-04-07
KR102518750B9 true KR102518750B9 (en) 2023-10-12

Family

ID=78703173

Family Applications (7)

Application Number Title Priority Date Filing Date
KR1020210042532A KR102518756B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates Polysaccharide capsule production of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042533A KR102518764B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates blood-brain barrier crossing of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042535A KR102518785B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates cell membrane stability of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042536A KR102518786B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates O-mannosylation of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042534A KR102518769B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates DNA damage response of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042531A KR102518750B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates melanin production of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042530A KR102518742B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates thermotolerance for mammalian body temperatures of Cryptococcus neoformans, and method for screening antifungal agents using the same

Family Applications Before (5)

Application Number Title Priority Date Filing Date
KR1020210042532A KR102518756B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates Polysaccharide capsule production of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042533A KR102518764B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates blood-brain barrier crossing of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042535A KR102518785B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates cell membrane stability of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042536A KR102518786B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates O-mannosylation of Cryptococcus neoformans, and method for screening antifungal agents using the same
KR1020210042534A KR102518769B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates DNA damage response of Cryptococcus neoformans, and method for screening antifungal agents using the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020210042530A KR102518742B1 (en) 2020-05-08 2021-04-01 Phosphatase that modulates thermotolerance for mammalian body temperatures of Cryptococcus neoformans, and method for screening antifungal agents using the same

Country Status (1)

Country Link
KR (7) KR102518756B1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160118162A (en) * 2016-07-25 2016-10-11 (주)앰틱스바이오 Novel target genes for anti-fungal agent of Cryptococcus neoformans and their use
KR102041684B1 (en) * 2016-11-21 2019-11-07 연세대학교 산학협력단 Use of Hsf1 gene for treating mycoses or meningoencephalitis

Also Published As

Publication number Publication date
KR102518785B1 (en) 2023-04-07
KR102518769B9 (en) 2023-10-12
KR102518742B1 (en) 2023-04-11
KR20210137384A (en) 2021-11-17
KR102518756B9 (en) 2023-10-12
KR20210137380A (en) 2021-11-17
KR102518764B1 (en) 2023-04-07
KR102518786B9 (en) 2023-10-12
KR20210137386A (en) 2021-11-17
KR102518786B1 (en) 2023-04-07
KR102518750B1 (en) 2023-04-07
KR20210137385A (en) 2021-11-17
KR20210137383A (en) 2021-11-17
KR102518742B9 (en) 2023-10-12
KR102518764B9 (en) 2023-10-12
KR20210137382A (en) 2021-11-17
KR102518769B1 (en) 2023-04-07
KR102518756B1 (en) 2023-04-07
KR102518785B9 (en) 2023-10-12
KR20210137381A (en) 2021-11-17

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E701 Decision to grant or registration of patent right
GRNT Written decision to grant
G170 Re-publication after modification of scope of protection [patent]