KR102484665B1 - Apparatus and method for providing genomic analysis results based on platform - Google Patents

Abstract

A method for providing a genome analysis result of a service server of the present invention comprises the steps of receiving a user's genome analysis request from a user device by a request reception unit, and interacting with the user device by an app generator method by an app builder (APP Builder) method. Generating a gene app that provides a report including a genome analysis result of analyzing a user's genome.

Description

Apparatus and method for providing genomic analysis results based on platform

The present invention relates to a technology for providing a genome analysis result, and more particularly, to an apparatus and method for providing a genome analysis result based on a platform.

With the development of technology, various services are provided through electronic devices. In response to various demands, studies on customized services based on additional information about users, beyond simple interactions with users, are also being actively conducted. For example, a service providing health-related information using genomic data is being considered.

In addition, technology related to a secure mobile application development platform that accesses sensitive data such as health information is introduced in Korean Patent Registration No. 10-2111180. According to this document, synergy is provided by providing developers with a simple interface to build applications, abstracting the complexities associated with security, application distribution and management. Additionally, built-in security, server synchronization and common development tools are available without requiring software developers to have knowledge of programming multiple mobile operating systems.

Korean Registered Patent No. 10-2111180 (published on May 08, 2020)

An object of the present invention is to provide an apparatus and method for providing a genome analysis result on a platform basis through a third party genome analysis app or a gene app generated by an app builder method.

A method for providing a genome analysis result of a service server of the present invention comprises the steps of receiving a user's genome analysis request from a user device by a request reception unit, and interacting with the user device by an app generator method by an app builder (APP Builder) method. Generating a gene app that provides a report including a genome analysis result of analyzing a user's genome.

Generating the gene app includes a step in which a marker selection module provides an interface and a user selects a marker used in the gene app, and a data sheet generation module performs a predetermined genome analysis algorithm based on the selected marker. Analyzing the user's genome data and generating a result sheet indicating the analysis result, and generating a report including the genome analysis result by a result matching module.

The marker is characterized in that it includes at least one of a single-type marker and a multi-type marker.

In the step of generating the result sheet, in the case of a multitype marker in which a plurality of single nucleotide polymorphisms (SNPs) are registered, the data sheet generation module derives an order ratio (OR) value by combining two or more SNPs.

The step of generating the report is characterized in that the result matching module generates a gene app including a report indicating the analysis result by connecting the selected marker and the risk analyzed according to a predetermined genome analysis algorithm.

The method for providing the genome analysis result of the service server of the present invention is an app management server so that the third party device can view the received genome analysis request of the user when the request receiving unit receives the user's genome analysis request from the user device. and, when a result providing unit derives a genome analysis result by a third party device corresponding to the user's genome analysis request, transmitting the derived genome analysis result to the user device.

In the step of delivering the derived genome analysis result to the user device, when the result providing unit stores the genome analysis result derived by the third party in the service storage, address information at which the genome analysis result is stored in the service storage is stored. Characterized in that it is delivered to the user device.

The user's genome analysis request is characterized in that it is made by selecting any one of a plurality of different genome analysis apps provided by a plurality of third parties.

App management server for providing the genome analysis results of the present invention, when the request preparation unit receives the user's genome analysis request from the service server, the user's genome data included in the user's genome analysis request is sequentially stored in the genome storage and file server A step of providing to be stored in, a request posting unit posting a third party device so that the user's genome analysis request can be viewed, and a result storage unit performing genome analysis by the third party device accepting the user's genome analysis request. When the result is derived, controlling the file server to store the derived genome analysis result in service storage, and when the information providing unit receives address information at which the genome analysis result on the service storage is stored from the file server, the received address and providing the information to the service server.

The posting may include providing location information of the user's genome data stored in the genome storage to a third party device accepting the user's genome analysis request by the request posting unit reading the user's genome analysis request, thereby providing the third party device with location information of the user's genome data stored in the genome storage. It is characterized in that it is downloaded.

The providing to be stored in the genome storage and file server includes the step of verifying the validity of the VCF file and the Genotyping Table among the user's genome information included in the user's genome analysis request by the request preparation unit; If the result is successful, the step of providing the request preparation unit to store the user's genome information.

The service server for providing the genome analysis results of the present invention includes a request receiving unit that receives a user's genome analysis request from a user device, and a genome that analyzes the user's genome by interacting with the user device in an APP Builder method and an app generator that generates a gene app that provides a report including analysis results.

The app creation unit analyzes and analyzes the user's genome data according to a predetermined genome analysis algorithm based on a marker selection module for providing an interface and allowing the user to select a marker used in the gene app, and the selected marker It includes a data sheet generation module that generates a result sheet indicating a result, and a result matching module that generates a report including a genome analysis result.

The marker is characterized in that it includes at least one of a single-type marker and a multi-type marker.

The data sheet generating module is characterized by deriving an order ratio (OR) value by combining two or more SNPs in the case of a multitype marker in which a plurality of single nucleotide polymorphisms (SNPs) are registered.

The result matching module is characterized by generating a gene app including a report indicating the analysis result by connecting the selected marker and the risk analyzed according to a predetermined genome analysis algorithm.

When the service server for providing genome analysis results of the present invention receives a user's genome analysis request from a user device, a request receiving unit that transmits the user's genome analysis request to the app management server so that a third party device can view it. and, when a genome analysis result is derived by a third party device corresponding to the user's genome analysis request, a result providing unit for transmitting the derived genome analysis result to the user device.

When the result providing unit stores the genome analysis result derived by the third party in the service storage, it is characterized in that it transfers address information where the genome analysis result is stored in the service storage to the user device.

The user's genome analysis request is characterized in that it is made by selecting any one of a plurality of different genome analysis apps provided by a plurality of third parties.

When receiving a user's genome analysis request from the service server, the app management server for providing genome analysis results of the present invention sequentially stores the user's genome data included in the user's genome analysis request in genome storage, and the file server The genome analysis result is provided by a request preparation unit that provides storage in the database, a request post unit that posts the user's genome analysis request so that the third party device can view it, and a third party device that accepts the user's genome analysis request. When the result storage unit controls the file server to store the derived genome analysis result in the service storage, and the address information in which the genome analysis result is stored on the service storage is received from the file server, the received address information is stored in the service storage. It includes an information providing unit provided to the server.

The request posting unit reads the user's genome analysis request and provides location information of the user's genome data stored in the genome storage to a third party device that has accepted the user's genome analysis request so that the third party device downloads the genome data. to be characterized

The request preparation unit verifies the validity of the VCF file and the Genotyping Table among the user's genome information included in the user's genome analysis request, and if the verification is successful, the user's genome information is provided to be stored. to be characterized

According to the present invention, by generating a gene app in the form of an app builder, individuals, researchers, companies, etc. can more easily create genome analysis applications. In particular, ordinary people who do not know programming can easily arrange the components of the gene app or edit the contents through the interface (WEB interface).

In addition, since several genome analysis apps developed by multiple third parties can be used, various genome analysis apps can be used by users.

1 is a diagram for explaining a system for providing a genome analysis result according to an embodiment of the present invention.
2 is a diagram for explaining a specific configuration of a service server according to an embodiment of the present invention.
3 is a diagram for explaining a specific configuration of an app management server according to an embodiment of the present invention.
4 is a flowchart illustrating a method for providing a genome analysis result according to an embodiment of the present invention.
5 is a flowchart for explaining a method for generating a genome analysis app that provides genome analysis results according to an embodiment of the present invention.
6 is a diagram for explaining a method for generating a genome analysis app that provides genome analysis results according to an embodiment of the present invention.
7 to 9 are screen examples for explaining a method for generating a genome analysis app that provides genome analysis results according to an embodiment of the present invention.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

In describing the embodiments, descriptions of technical contents that are well known in the technical field to which the present invention pertains and are not directly related to the present invention will be omitted. This is to more clearly convey the gist of the present invention without obscuring it by omitting unnecessary description.

In the drawings, like reference numerals are assigned to like components. On the other hand, singular or plural expressions for components are appropriately selected according to the presented circumstances for convenience of description, and the present invention is not limited to singular or plural forms. Elements expressed in the singular form may be interpreted as plural elements, and vice versa.

First, a system for providing a genome analysis result according to an embodiment of the present invention will be described. 1 is a diagram for explaining a system for providing a genome analysis result according to an embodiment of the present invention.

Referring to FIG. 1, the genome analysis system 1 according to an embodiment of the present invention analyzes the user's genome data to confirm the mutation of a specific gene and to make the characteristics of the trait easy for the general public to know. Provides a report containing This genome analysis system 1 includes a user device 10, a third party device 20, a service server 100, a web management server 200, a genome storage 300, a file server 400, and a service storage ( 500) are included.

The user device 10 is a device used by a user who wants to receive a genome analysis service, and can receive a genome analysis service provided by the service server 100 by accessing the service server 100 through a network. The user device 10 may be various types of electronic devices such as a smart phone, a tablet, a phablet, a notebook computer, a personal computer (PC), and a mobile internet device (MID).

The third party device 20 is a device used by a developer developing a genome analysis app. The third party device 10 receives a user's genome analysis request through the app management server 200, performs genome analysis using the genome analysis algorithm of the third party, and provides the genome analysis result as a report.

The service server 100 provides a report including a genome analysis result according to a user's genome analysis request. At this time, the service server 100 may provide a report of genome analysis performed by the third party device 20 or provide a gene app generated by interacting with the user device 10 in an APP Builder method. there is. Here, the gene app may be a report including a genome analysis result. The service server 100 connects to the user device 10 to receive a genome analysis request and serves to provide the received genome analysis result. To this end, the service server 100 posts different genome analysis algorithms or genome analysis apps of a plurality of third parties according to an embodiment of the present invention, and the user who wants to analyze the genome uses the published genome analysis algorithm or genome analysis app. A genome analysis algorithm or a genome analysis app can be selected through the user device 10 . In addition, when providing a genome analysis result, the service server 100 enables a user to select one of a service in which a report is created by a third party and a method in which a report is prepared by a user's input.

The app management server 200 is a server for operating an app market that manages genome analysis apps. The app management server 200 forwards the user's genome analysis request received by the service server 100 to the third party device 20, and sends a report including the genome analysis result by the third party device 20 to the service server ( 100) can be passed. At this time, the report including the genome analysis result is delivered by providing address information where the report is stored instead of directly delivering the report.

The dielectric storage 300 is for storing user's genome data. The genome storage 300 may store genome data provided by a user through the app management server 200 . Dielectric storage 300 may be a storage server.

The file server 400 transfers the user's genome data to the third party device 20 and stores the user's genome data while the third party device 20 performs genome analysis. In addition, the file server 400 may store in the service storage 500 a report including a result of genome analysis performed by the third party device 20 . This file server 400 may be a File Transfer Protocol (FTP) file server.

The service storage 500 is for storing reports including genome analysis results. The service storage 500 receives a report including a genome analysis result from the file server 400 and stores it. And it can return address information indicating the path where the report is stored. This service storage 500 may be a storage server.

The present invention relates to network computing with various types of computer system configurations including personal computers, laptop computers, handheld devices, multiprocessor systems, network PCs, minicomputers, mainframe computers, mobile phones, PDAs, pagers, and the like. In the environment, it can be applied to providing services for medical or genomic data management according to an embodiment of the present invention to the computer systems. The user device 10, the third party device 20, the service server 100, the web management server 200, the dielectric storage 300, the file server 400, and the service storage 500 are connected to each other through a network. can

According to one embodiment of the invention, it can be implemented in a distributed system environment where both local and remote computer systems linked by wired data links, wireless data links, or a combination of wired and wireless data links through a network perform tasks. . In a distributed system environment, program modules may be located in local and remote memory storage devices.

According to another embodiment, the network may include a wireless communication network such as WLAN (Wireless LAN), Wi-Fi, Wibro, Wimax, HSDPA (High Speed Downlink Packet Access), the system Depending on the implementation method, wired communication networks such as Ethernet, xDSL (ADSL, VDSL), HFC (Hybrid Fiber Coaxial Cable), FTTC (Fiber to The Curb), FTTH (Fiber To The Home) may be included. In addition, the network of the present invention may include, for example, a mobile communication network consisting of a plurality of access networks (not shown) and a core network (not shown) connecting them. Here, the access network is a network that is directly connected to a terminal and performs wireless communication. For example, a plurality of base stations such as BS (Base Station), BTS (Base Transceiver Station), NodeB, eNodeB, etc. , may be implemented as a base station controller such as a radio network controller (RNC). In addition, as described above, the digital signal processing unit and the radio signal processing unit integrally implemented in the base station are divided into digital units (hereinafter referred to as DUs) and radio units (hereinafter referred to as RUs), A plurality of RUs (not shown) may be installed in a plurality of areas, and the plurality of RUs may be configured by connecting a centralized DU In addition, a core network (not shown) constituting a mobile network together with an access network is It serves to connect other communication networks such as an external network, for example, the Internet. As described above, the core network is a network system that performs major functions for mobile communication services such as mobility control and switching between access networks, It performs circuit switching or packet switching, manages and controls packet flow within the mobile network, manages inter-frequency mobility, and manages traffic and other traffic within the access network and the core network. It can also play a role for interworking with a network, such as the Internet, such as the Serving GateWay (SGW), PDN GateWay (PGW), Mobile Switching Center (MSC), Home Location Register (HLR), Mobile Mobility Entity) and HSS (Home Subscriber Server), etc. In addition, the network according to the present invention may include an Internet network, in which information is exchanged according to the TCP / IP protocol. means an open communication network, that is, a public network.

Next, a detailed configuration of the service server 100 according to an embodiment of the present invention will be described. 2 is a diagram for explaining a specific configuration of a service server according to an embodiment of the present invention. Referring to FIG. 2 , the service server 100 includes a request receiving unit 110, a result providing unit 120, an app generating unit 130, a content recommendation unit 140, and a history storage unit 150.

The request reception unit 110 is for receiving a user's genome analysis request. At this time, the request reception unit 110 receives a genome analysis request to provide a report on which genome analysis has been performed by the third party device 20, or genome analysis to provide a gene app generated by the APP Builder method request can be received. Here, the gene app may be a report including a genome analysis result. The request receiving unit 110 may post a plurality of different genome analysis apps (APPs) or algorithms provided by a plurality of third parties through a predetermined page (eg, a web application page) so that the user can select them.

When a genome analysis result is derived by the third party device 20 in response to a user's genome analysis request, the result providing unit 120 delivers the derived genome analysis result to the user device 10 . At this time, when the genome analysis result derived by the third party device 20 is stored in the service storage 500, the result providing unit 120 provides address information where a report including the genome analysis result is stored in the service storage 500. It is delivered to the user device 10.

The app generator 130 is for generating a gene app according to an embodiment of the present invention. Here, the gene app may be a report including a genome analysis result. This app generation unit 130 includes a marker selection module 131, a data sheet generation module 133, and a result matching module 135.

The marker selection module 131 is for selecting markers to be used in the gene app. The data sheet generation module 133 analyzes the user's genome data according to a predetermined genome analysis algorithm and generates a result sheet indicating the analysis result. The result matching module 135 is for generating a report including a genome analysis result. The app generator 130 including the marker selection module 131, the data sheet generation module 133, and the result matching module 135 will be described in more detail below.

The content recommendation unit 140 may recommend a genetically suitable product to the user according to the result of the genetic test. For example, the user's skin condition, ie, whether the skin is sensitive, dry, or oily, can be determined according to a genetic test result, and cosmetics can be recommended accordingly. In addition, according to the result of the genetic test, the user's degree of classification of sweet, sour, and bitter tastes can be grasped, and wine can be recommended accordingly. In addition, according to the result of the genetic test, the user's physical condition, for example, body type, constitution, BMI, etc. may be grasped, and diet and exercise may be recommended accordingly.

The history storage unit 150 may store operation history of the user's genome information in a blockchain network (not shown). The history storage unit 150 may transmit and store a log in which the genome information received from the user device 10 is used to a blockchain network (not shown). Accordingly, if necessary, it is possible to provide the user device 10 with a log indicating details of operating the user's genome information.

Next, a detailed configuration of the app management server 200 according to an embodiment of the present invention will be described. 3 is a diagram for explaining a specific configuration of the app management server 200 according to an embodiment of the present invention. Referring to FIG. 3 , the app management server 200 includes a request preparation unit 210, a request posting unit 220, a result storage unit 230, and an information providing unit 240.

Upon receiving the user's genome analysis request from the service server 100, the request preparation unit 210 sequentially stores the user's genome data included in the user's genome analysis request in the genome storage 300 and the file server 400. provide to do At this time, the request preparation unit 210 verifies the validity of the VCF file and the Genotyping Table among the user's genome data included in the user's genome analysis request, and if the verification is successful, the user's genome data is stored. to provide.

The request posting unit 220 posts so that the third party device 20 can view the user's genome analysis request. At this time, the request post unit 220 reads the user's genome analysis request and provides location information of the user's genome data stored in the genome storage 300 to the third party device 20 that has accepted the user's genome analysis request, The party device 20 can be downloaded.

The result storage unit 230 is for storing a report including a genome analysis result in the service storage 500 . When the third party device 20 accepting the user's genome analysis request performs genome analysis and derives a report including the genome analysis result, the derived report is uploaded and stored in the file server 400 . Then, the result storage unit 230 controls the file server 200 to store the report including the derived genome analysis result in the service storage 500 .

The information providing unit 240 is to provide the service server 100 with address information of a report including a genome analysis result. After the service storage 500 stores the report including the genome analysis result, it returns the address information where the report is stored to the file server 400, and the file server 400 sends the address information to the app management server 200. to provide. Then, when the information providing unit 240 receives address information in which a report including a genome analysis result on the service storage 500 is stored from the file server 400 , it transmits the received address information to the service server 100 .

Next, a method for providing a genome analysis result according to an embodiment of the present invention will be described. 4 is a flowchart illustrating a method for providing a genome analysis result according to an embodiment of the present invention.

Referring to FIG. 4 , the request reception unit 110 of the service server 100 transfers a plurality of different genome analysis apps (APPs) provided by a plurality of third party devices 20 to a predetermined page (eg, a web application page). can be posted via Then, the user device 10 may access the service server 100 and display a plurality of genome analysis apps on the screen through the corresponding page. Then, the user can browse these plural genome analysis apps and request genome analysis by selecting a desired genome analysis app.

Accordingly, the user device 10 may request genome analysis from the service server 100 according to the input of the user's genome analysis request order in step S110. The user's genome analysis request includes order information (APP ID, MGB ID, Price) and the user's genome data. The order information includes information for identifying the selected genome analysis app (APP ID), information for identifying the individual user (MGB ID), and cost (Price). Accordingly, the request reception unit 110 of the service server 100 may receive a user's genome analysis request from the user device 10 . Then, the request reception unit 110 transmits the user's genome analysis request received in step S120 to the app management server 200.

The request preparation unit 210 of the app management server 200 verifies the validity of the VCF (Variant Call Format) file and the Genotyping Table among the user's genome data included in the user's genome analysis request in step S130. . Here, the VCF (Variant Call Format) file is a text file format containing information on mutations found at a specific location, and the Genotyping Table is a text format file containing DNA data. If this verification result is successful, the request preparation unit 210 of the app management server 200 provides the user's genome data to the genome storage 300. Accordingly, the file server 400 may download the user's genome data from the genome storage 300 to deliver to the third party device 20 in step S140.

On the other hand, the request posting unit 220 of the app management server 200 posts so that the third party device 20 can view the user's genome analysis request. Accordingly, the third party device 20 accesses the app management server 200 in step S150 and sends a genome analysis request using its own genome analysis app through identification information (APP ID) of its own genome analysis app among order information. You can check.

Accordingly, the third party device 20 that confirms the genome analysis request and accepts it downloads genome data from the file server 400 in step S160, performs genome analysis in step S170, and reports including the genome analysis result. generate Subsequently, the third party device 20 uploads the report generated in step S180 to the file server 400 . Then, the third party device 20 transmits to the app management server 200 a message (Order Complete) indicating that the genome analysis has been completed, including location information where the report on the file server 400 is stored, in step S190.

Then, the result storage unit 230 of the app management server 200 transmits a control command to store the report including the genome analysis result stored in the file server 400 in the service storage 500 in step S200. Then, the file server 400 transmits a report including the genome analysis result to the service storage 500 in step S210. Accordingly, the service storage 500 stores a report including a genome analysis result and returns address information where the report is stored.

When the report is saved, the file server 400 erases the information stored in the file server 400, that is, the user's genome data, in step S220. Then, the file server 400 transmits a message indicating that the genome analysis process has been completed (3rd Processing Complete) to the app management server 200 together with the address information where the report is stored in step S230. Accordingly, the app management server 200 may receive address information in which a report including a genome analysis result on the service storage 500 is stored. Then, the information provider 240 of the app management server 200 provides the address information received in step S240 to the service server 100 .

When the service server 100 receives this address information, the result provider 120 of the service server 100 provides the genome analysis result derived by the third party device 20 in step S250. At this time, the result providing unit 120 of the service server 100 may provide the genome analysis result by transferring address information in which the report including the genome analysis result is stored in the service storage 500 to the user device 10 . The user device 10 receiving the address information downloads a report including the genome analysis result through the corresponding address information and displays it on the screen, and the user can view this report.

Next, a method for generating a genome analysis app that provides genome analysis results according to an embodiment of the present invention will be described. 5 is a flowchart for explaining a method for generating a genome analysis app that provides genome analysis results according to an embodiment of the present invention. 6 is a diagram for explaining a method for generating a genome analysis app that provides genome analysis results according to an embodiment of the present invention. 7 to 9 are screen examples for explaining a method for generating a genome analysis app that provides genome analysis results according to an embodiment of the present invention.

Referring to FIGS. 5 to 9 , the request receiving unit 110 of the service server 100 may receive a request from the user device 10 to create a gene app using an App Builder method. Then, this request can be provided to the app generator 130 . The app generator 130 basically provides the user device 10 with an interface for generating a gene app. Accordingly, the user device 10 displays the corresponding interface. The user can select a selection provided through the menu of the interface, and if such a selection is made, the user device 10 transmits the user's selection to the service server 100 . Then, the app generator 130 generates a gene app according to the user's selection. Therefore, a detailed description of a procedure for the user device 10 to transmit the user's selection is omitted below.

After the request reception unit 110 receives a request from the user device 10 to create a gene app in an App Builder method, and provides an interface for generating a gene app, the app creation unit 130 receives basic information about the app according to the user's selection in step S310. Basic information includes App Name, App Description, Gender, Category, Nation, Race Group, App Price, App Icon etc. may be included. Also, the basic information may include the user's genome data. Subsequently, the marker selection module 131 of the app generator 130 selects a marker to be used in the gene app according to the user's selection in step S320.

At this time, as shown in FIG. 6, the marker selection module 131 registers single-type markers and multi-type markers at the item level, and among the single-type markers and multi-type markers to be used in the Gene app according to the user's input markers can be selected. Single-type markers are selected when the whole can be explained by one marker, such as bronchospasm and alcohol flushing, and multi-type markers are selected when multiple genes such as baldness-related genes, eye color-related genes, and diabetes act. can be chosen

When the marker is selected, the data sheet generation module 133 of the app generator 130 constructs a result sheet showing the result of analyzing the genome for each marker selected previously (S320) in step S330. That is, the user's genome data is analyzed according to a predetermined genome analysis algorithm based on the selected marker, and a result sheet indicating the analysis result is generated.

An example of an interface provided by the marker selection module 131 is illustrated in FIGS. 7 and 8 . Referring to FIG. 7, when a single marker is selected, the data sheet generation module 133 describes only one rsID (Reference SNP ID) and gene, and two allele lists according to a predetermined genome analysis algorithm , that is, normal alleles and risk alleles are derived. In particular, in the case of OR (Order Ratio) values, the data sheet generation module 133 derives the risk when both NNs have normal alleles, and NRs one normal allele (Normal allele ) and the risk of having one risk allele, and RR derives the risk of having both risk alleles.

Referring to FIG. 8 , multitype markers can be used when a phenotype or disease is to be interpreted with a plurality of markers. Since the value ranges of a plurality of markers are diverse, the user can check the minimum and maximum value ranges and divide them into 3 levels (Low, Typical, High) or 5 levels. In FIG. 8, “Check Order” indicates High when the risk is high and selects 'High score, High risk'. there is. In particular, in the case of multitype markers, a plurality of single nucleotide polymorphisms (SNPs) can be registered. According to an embodiment, when a plurality of SNPs are registered, the data sheet generating module 133 derives an OR value of each of the plurality of SNPs. Also, according to another embodiment, the data sheet generation module 133 may derive an OR value by combining two or more SNPs.

On the other hand, if there is a result of analyzing the genome according to the previously selected marker, the result matching module 135 additionally inputs the previous result sheet in step S340, and the comprehensive result including the previous result sheet and the current result sheet in step S350. create a ji For example, a single result sheet may be generated by selecting different single-type markers, repeating steps S320 and S330, and merging a plurality of results in steps S340 and S350. On the other hand, if there is no genome analysis result according to the previously selected marker, steps S340 and S350 are omitted.

Next, the result matching module 135 generates a report including at least one result sheet in step S360. That is, at this time, the result matching module 135 connects the selected marker and the risk level analyzed according to a predetermined genome analysis algorithm to generate a report showing the analysis result of analyzing the user's genome data.

At this time, the result matching module 135 provides an interface as shown in FIG. 9 . This interface can be an editor capable of editing the arrangement of components of the genome analysis result on a report. Therefore, according to the user's input, the result matching module 135 may edit the contents included in the report in step S360.

According to one embodiment of the present invention as described above, by generating a gene app in the form of an app builder, individuals, researchers, companies, etc. can more easily create genome analysis applications. In particular, ordinary people who do not know programming can easily arrange the components of the gene app or edit the contents through the interface (WEB interface).

On the other hand, according to an additional embodiment, although not shown, after the procedure of the embodiment of FIG. 4 or 5 is completed, the result providing unit 140 may additionally recommend a genetically suitable product to the user according to the genetic test result. there is. For example, the user's skin condition, ie, whether the skin is sensitive, dry, or oily, can be determined according to the result of the genetic test, and cosmetics can be recommended accordingly. In addition, according to the result of the genetic test, the user's degree of classification of sweet, sour, and bitter tastes can be grasped, and wine can be recommended accordingly. In addition, according to the result of the genetic test, the user's physical condition, for example, body type, constitution, BMI, etc. may be grasped, and diet and exercise may be recommended accordingly.

In addition, although not shown, after the procedure of the embodiment of FIG. 4 or 5 is completed, the history storage unit 150 additionally stores the history of operating the user's genome information in a blockchain network (not shown). can The history storage unit 150 may transmit and store a log in which the genome information received from the user device 10 is used to a blockchain network (not shown). Accordingly, if necessary, it is possible to provide the user device 10 with a log indicating details of operating the user's genome information. Accordingly, since manipulation is impossible in the case of blockchain, it is possible to transparently provide the operation history of the user's genome information.

Meanwhile, the methods according to the embodiments of the present invention described above may be implemented in a program form readable by various computer means and recorded on a computer readable recording medium. Here, the recording medium may include program commands, data files, data structures, etc. alone or in combination. Program instructions recorded on the recording medium may be those specially designed and configured for the present invention, or those known and usable to those skilled in computer software. For example, recording media include magnetic media such as hard disks, floppy disks and magnetic tapes, optical media such as CD-ROMs and DVDs, and magneto-optical media such as floptical disks ( magneto-optical media), and hardware devices specially configured to store and execute program instructions, such as ROM, RAM, flash memory, and the like. Examples of program commands may include high-level language wires that can be executed by a computer using an interpreter, as well as machine language wires such as those produced by a compiler. These hardware devices may be configured to act as one or more software modules to perform the operations of the present invention, and vice versa.

The present invention has been described above using several preferred examples, but these examples are illustrative and not limiting. As such, those skilled in the art to which the present invention belongs will understand that various changes and modifications can be made according to the doctrine of equivalents without departing from the spirit of the present invention and the scope of rights set forth in the appended claims.

10: user device
20: Third Party Devices
100: service server
200: App management server
300: dielectric storage
400: file server
500: service storage

Claims (22)

In the method for providing a genome analysis result of the service server,
Receiving a user's genome analysis request from a user device by a request reception unit; and
Generating a gene app that provides a report including a genome analysis result of analyzing a user's genome by interacting with the user device in an app builder method by an app generator;
Including,
The step of creating the gene app is
Selecting a marker to be used in the gene app by a user by providing an interface by a marker selection module;
analyzing the user's genome data according to a predetermined genome analysis algorithm based on the selected marker by a data sheet generating module, and generating a result sheet indicating the analysis result; and
Generating, by a result matching module, a report including a genome analysis result;
characterized in that it includes
A method for providing a genome analysis result of a service server. delete According to claim 1,
The marker
Characterized in that it includes at least one of a single marker and a multi-type marker
A method for providing a genome analysis result of a service server. According to claim 3,
The step of generating the result sheet is
In the case of a multitype marker in which a plurality of single nucleotide polymorphisms (SNPs) are registered, the data sheet generation module derives an order ratio (OR) value by combining two or more SNPs. Characterized in that
A method for providing a genome analysis result of a service server. According to claim 1,
Steps to generate the report
Characterized in that the result matching module generates a gene app including a report showing the analysis result by connecting the selected marker and the risk analyzed according to a predetermined genome analysis algorithm
A method for providing a genome analysis result of a service server. delete delete delete In the app management server for providing genome analysis results,
When the request preparation unit receives the user's genome analysis request from the service server, providing the user's genome data included in the user's genome analysis request to be sequentially stored in a genome storage and a file server;
Posting a request posting unit so that a third party device can view the user's genome analysis request;
controlling a file server so that a result storage unit stores the derived genome analysis result in a service storage when a genome analysis result is derived by a third party device accepting the user's genome analysis request; and
providing the received address information to the service server when the information providing unit receives the address information in which the genome analysis result on the service storage is stored from the file server;
Including,
The step of providing to be stored in the genome storage and file server
verifying the validity of a VCF file and a Genotyping Table among genome information of the user included in the user's genome analysis request by the request preparation unit;
If the verification result is successful, providing the request preparation unit to store the user's genome information;
characterized in that it includes
A method for providing genome analysis results from the app management server. According to claim 9,
The posting step is
The request posting unit reads the user's genome analysis request and provides location information of the user's genome data stored in the genome storage to a third-party device that has accepted the user's genome analysis request so that the third-party device downloads it. characterized
A method for providing genome analysis results from the app management server. delete In the service server for providing genome analysis results,
a request receiving unit for receiving a user's genome analysis request from a user device; and
App builder (APP Builder) method interacts with the user device to create an app generating a gene app that provides a report including a genome analysis result of the user's genome analysis;
Including,
The app creator
A marker selection module for providing an interface so that a user can select a marker used in the gene app;
a data sheet generation module that analyzes the user's genome data according to a predetermined genome analysis algorithm based on the selected marker and generates a result sheet indicating the analysis result; and
A result matching module for generating a report including a genome analysis result;
characterized in that it includes
A service server for providing genome analysis results. delete According to claim 12,
The marker
Characterized in that it includes at least one of a single marker and a multi-type marker
A service server for providing genome analysis results. According to claim 14,
The data sheet generation module
In the case of multitype markers in which multiple SNPs (Single nucleotide polymorphisms) are registered, an OR (Order ratio) value is derived by combining two or more SNPs
A service server for providing genome analysis results. According to claim 12,
The result matching module
Characterized in that generating a gene app including a report showing the analysis result by connecting the selected marker and the risk analyzed according to a predetermined genome analysis algorithm
A service server for providing genome analysis results. delete delete delete In the app management server for providing genome analysis results,
When receiving a user's genome analysis request from the service server, a request preparation unit for sequentially storing the user's genome data included in the user's genome analysis request in a genome storage and providing the storage in a file server;
A request posting unit for posting so that the third party device can read the user's genome analysis request;
a result storage unit controlling a file server to store the derived genome analysis result in a service storage when a genome analysis result is derived by a third party device accepting the user's genome analysis request; and
an information provider configured to provide the received address information to a service server when address information in which the genome analysis result is stored in the service storage is received from the file server;
Including,
The request preparation department
Verifying the validity of the VCF file and the Genotyping Table among the user's genome information included in the user's genome analysis request,
If the verification result is successful, characterized in that the user's genome information is provided to be stored
App management server for providing genome analysis results. According to claim 20,
Posting the request
Reading the user's genome analysis request and providing location information of the user's genome data stored in the genome storage to a third party device that has accepted the user's genome analysis request so that the third party device downloads
App management server for providing genome analysis results. delete

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