KR102394534B1 - System for evaluating improving ability of skin elasticity, and method for evaluating improving ability of skin elasticity using the same - Google Patents

Abstract

The present invention relates to a skin elasticity improvement evaluation system, and more particularly, to a skin elasticity improvement evaluation system reflecting total skin deformation and viscoelastic deformation, and a skin elasticity improvement evaluation method using the same.
According to the present invention, by using the elasticity index that reflects the actual total deformation and viscoelastic deformation of the skin, the skin elasticity change can be intuitively expressed numerically and expressed compared to the conventional indexes that do not detect a significant change in elasticity, and accordingly The improvement of skin elasticity of a substance or product can be evaluated more objectively and accurately. Therefore, it is easy to test substances that improve skin elasticity and verify the efficacy of products, and it can be helpful in providing consumers with appropriate skin care methods such as selection of appropriate substances or products and beauty information according to the evaluation results.

Description

Skin elasticity improvement evaluation system and skin elasticity improvement evaluation method using the same

The present invention relates to a skin elasticity improvement evaluation system, and more particularly, to a skin elasticity improvement evaluation system reflecting total skin deformation and viscoelastic deformation, and a skin elasticity improvement evaluation method using the same.

Unlike insects with a hard epidermis, human skin has an endoskeletal structure and consists of several layers of soft but elastic cellular tissue on the outside of the skeleton and muscles. Such skin has elasticity-related characteristics such as various viscosity and elasticity such as the degree of firmness or elongation of the skin depending on various factors such as the degree of bonding and thickness between cells or tissues constituting the tissue. show various aspects. These elasticity characteristics of the skin appear to be reduced or changed due to the aging of the skin itself and tissue changes due to wound healing, etc., and aging along with other tissue changes such as muscle changes as the age increases, along with decreased elasticity of the skin, sagging or wrinkles It is known as one of the indicators of

Therefore, it can be said that improving the elasticity lowering due to skin aging is one of the main efficacy characteristics in cosmetics, and accordingly, substances that have or are expected to have an effect of improving skin elasticity (eg, artificial synthetic compounds, natural extracts, etc.) Alternatively, measuring skin elasticity is also considered important in product efficacy evaluation.

Various measuring devices are used to measure skin elasticity, and one of them is to check skin elasticity by inducing deformation of the skin by applying a certain negative pressure to the skin. Among them, R0, which represents skin extensibility/flexibility through skin deformation, measures the length of the total skin deformed by negative pressure for a certain period of time. UV, viscoelastic contribution in deformation of skin). In addition, R6 using the ratio of the two components represents the skin viscoelastic deformation (Uv/Ue).

However, in general, when the skin ages, the elastic deformation decreases and the viscous deformation increases. Therefore, when both components increase or decrease in the same way, it may not be possible to accurately detect changes due to skin aging with the existing R0 and R6. (DOBREV, Hristo. Cutometer®. In: Non Invasive Diagnostic Techniques in Clinical Dermatology. Springer Berlin Heidelberg, 2014. p. 315-338.; AKHTAR, NAVEED, et al. Calendula extract: effects on mechanical parameters of Human skin. Acta Pol. Pharm, 2011, 68.5: 693-701.).

Republic of Korea Patent Publication No. 10-1116204 Republic of Korea Patent Publication No. 10-2015-0041876

The present invention can intuitively express changes in skin elasticity compared to conventional indices that do not detect a significant change in elasticity by using an elasticity index that reflects the actual total deformation and viscoelastic deformation of the skin, and, accordingly, An object of the present invention is to provide a skin elasticity improvement evaluation system and method that can more objectively and accurately evaluate the improvement of skin elasticity.

Skin elasticity improvement evaluation system according to the features of the present invention for achieving the above object,

a skin elasticity measuring unit for measuring skin elasticity by inducing deformation of the skin by applying a certain negative pressure to the skin, and deriving a total deformation (R0) and viscoelastic deformation rate (R6) of the skin;

a calculation unit for calculating the skin elasticity measurement value (A) by processing the total deformation (R0) and viscoelastic deformation rate (R6) of the skin derived from the skin elasticity measurement unit by the following formula (1); and

It is characterized in that it includes a skin elasticity improvement evaluation unit for evaluating the skin elasticity improvement degree using the skin elasticity measurement value (A) calculated by the calculation unit.

A = R0/R6 = {Ue(Uv+Ue)}/Uv … … Formula (1)

Here, immediate deformation (Ue) represents elastic deformation of the skin, viscoelastic contribution in deformation of skin (Uv) represents viscous deformation of the skin, R0 is Uv+Ue, and R6 is Uv/Ue.

In addition, the method for evaluating skin elasticity improvement according to the characteristics of the present invention for achieving the above object,

(1) The skin elasticity measuring unit applies a certain negative pressure to the skin before and after the application of the substance or product to evaluate the skin elasticity improvement effect, induces skin deformation, measures skin elasticity, and measures the total deformation (R0) and viscoelastic deformation rate of the skin deriving (R6);

(2) The calculation unit processes the total deformation (R0) and viscoelastic deformation rate (R6) of the skin before and after application of the substance or product derived in step (1) with the following formula (1), respectively, before and after application of the substance or product calculating a skin elasticity measurement value (A); and

(3) Comprising the step of evaluating the improvement in skin elasticity by comparing the skin elasticity measurement value (A) before and after application of the substance or product calculated in step (2) by the skin elasticity improvement evaluation unit do it with

A = R0/R6 = {Ue(Uv+Ue)}/Uv … … Formula (1)

Here, immediate deformation (Ue) represents elastic deformation of the skin, viscoelastic contribution in deformation of skin (Uv) represents viscous deformation of the skin, R0 is Uv+Ue, and R6 is Uv/Ue.

According to the present invention, by using the elasticity index that reflects the actual total deformation and viscoelastic deformation of the skin, the skin elasticity change can be intuitively expressed numerically and expressed compared to the conventional indexes that do not detect a significant change in elasticity, and accordingly The improvement of skin elasticity of the product can be evaluated more objectively and accurately. Therefore, it is easy to test a substance that improves skin elasticity and to verify the efficacy of a product, and it can be helpful in providing consumers with an appropriate skin care method such as selection of a suitable product and beauty information according to the evaluation result.

1 is a diagram schematically illustrating a skin elasticity improvement evaluation system according to an embodiment of the present invention.
2 is a graph showing the elasticity measurement method used in the cutometer sensor.
3 is a diagram illustrating a flowchart of a method for evaluating skin elasticity improvement according to an embodiment of the present invention.
4 is a graph comparing and analyzing the existing elasticity index for each part according to Test Example 1.
5 is a graph comparing and analyzing the skin elasticity measurement value (A) used in the calculation unit of the skin elasticity improvement evaluation system according to the present invention according to Test Example 1 for each part.
6 is a graph comparing and analyzing the evaluation of the skin elasticity improvement effect of the product according to Test Example 2 using the existing elasticity index and the skin elasticity measurement value (A) according to the present invention.

Hereinafter, the skin elasticity improvement evaluation system and method according to the present invention will be described in detail.

In the present invention, unless otherwise defined, a substance means a substance that has or is expected to have an effect of improving skin elasticity, and this substance is used as a main component of a functional cosmetic for improving skin elasticity, or skin elasticity of other main ingredients It can also be used as an auxiliary ingredient for the purpose of improving or boosting the improvement function.

1 is a diagram schematically illustrating a skin elasticity improvement evaluation system according to an embodiment of the present invention. As shown in FIG. 1 , the skin elasticity improvement evaluation system according to an embodiment of the present invention includes a skin elasticity measurement unit 100 , a calculation unit 200 , and a skin elasticity improvement evaluation unit 300 . can be

The skin elasticity measurement unit 100 applies a certain negative pressure to the skin to induce deformation of the skin, measures skin elasticity, and derives a total deformation (R0) and a viscoelastic deformation rate (R6) of the skin. The skin elasticity measurement unit 100 may use the elasticity measurement method used in a conventionally known cutometer sensor.

More specifically, in the method of measuring elasticity used in the cutometer sensor, the degree of skin elasticity may be expressed as the total deformation (R0) of the skin and the rate of viscoelastic deformation (R6) of the skin. The total deformation (R0) of the skin is an index indicating the extensibility and flexibility of the skin, and is expressed as Ue+Uv in FIG. 2 . The viscoelastic strain rate R6 of the skin is an index indicating the viscous and elastic strain of the skin, and is expressed as Uv/Ue in FIG. 2 .

Each indicator shown in FIG. 2 is as follows.

Ue: immediate deformation

UV: viscoelastic contribution in deformation of skin

Uf(=R0): total distention

Ur: immediate recovery of skin after vacuum removal

Ua: viscoelastic contribution in recovering of skin

The skin elasticity improvement evaluation system according to the present invention can intuitively represent changes in skin elasticity using Ue and Uv among the indicators shown in FIG. 2 . More specific details regarding the elasticity index will be described in detail later with reference to Test Example 1, FIGS. 4 and 5 .

The calculating unit 200 calculates the skin elasticity measurement value (A) by processing the total deformation (R0) and the viscoelastic deformation rate (R6) of the skin derived from the skin elasticity measuring unit 100 by Equation 1 below.

[Equation 1]

A = R0/R6 = {Ue(Uv+Ue)}/Uv

The skin elasticity improvement evaluation unit 300 evaluates the skin elasticity improvement degree using the skin elasticity measurement value A calculated by the operation unit 200 .

More specifically, according to an embodiment of the present invention, the skin elasticity measuring unit 100 measures each skin elasticity with respect to the skin before and after application of any material or product to evaluate the skin elasticity improvement effect, and can derive the total strain (R0) and viscoelastic strain (R6) of and calculates a skin elasticity measurement value (A) before and after application of the substance or product, and the skin elasticity improvement evaluation unit 300 compares the skin elasticity measurement value (A) before and after application of the substance or product to the skin The degree of elasticity improvement can be evaluated.

At this time, the skin elasticity improvement evaluation unit 300 evaluates that the skin elasticity improvement effect is present when the increase rate of the skin elasticity measurement value (A) before and after application of the substance or product is 5% or more. That is, the skin elasticity improvement evaluation unit 300 may calculate the difference between the skin elasticity measurement values (A) before and after application of the material or product, and finally evaluate the skin elasticity improvement level of the material or product.

That is, the skin elasticity improvement evaluation system according to the present invention measures the elasticity of the skin and evaluates the improvement in the elasticity of the skin using a value calculated by processing the result with a predetermined specific formula, thereby improving the elasticity of the skin. It is easy to test substances and verify the efficacy of products.

In addition, although not shown in the drawings, according to an embodiment, the skin elasticity improvement evaluation system according to the present invention includes an output unit 400 for outputting the skin elasticity improvement evaluation result in the skin elasticity improvement evaluation unit 300 . ) may be further included.

The output unit 400 may output the skin elasticity improvement evaluation result in a visual or auditory manner, and if it is a device capable of outputting the skin elasticity improvement evaluation result in the above manner, the output unit 400 is not limited. can be implemented.

3 is a diagram illustrating a flowchart of a method for evaluating skin elasticity improvement according to an embodiment of the present invention. As shown in FIG. 3 , in the method for evaluating skin elasticity improvement according to an embodiment of the present invention, the skin elasticity measuring unit 100 applies a substance or product to evaluate the skin elasticity improvement effect on the skin before and after application, respectively. Inducing deformation of the skin by applying a constant negative pressure step (S100) of measuring skin elasticity and deriving the total deformation (R0) and viscoelastic deformation rate (R6) of the skin (S100), the operation unit 200 applies the material or product derived in step S100 Calculating the skin elasticity measurement value (A) before and after application of the substance or product by processing the total deformation (R0) and viscoelastic deformation rate (R6) of the skin before and after using a predetermined formula (S200), and evaluation of skin elasticity improvement The unit 300 may be implemented including a step (S300) of evaluating the improvement in skin elasticity by comparing the measured skin elasticity values (A) before and after application of the material or product calculated in step S200.

In addition, although not shown in the drawings, according to the embodiment, the skin elasticity improvement evaluation unit 300 compares the skin elasticity measurement value (A) before and after application of the material or product calculated in step S200 to evaluate the skin elasticity improvement degree It may further include a step (S400) of doing.

The steps S100 to S400 are performed by the skin elasticity measuring unit 100, the calculating unit 200, the skin elasticity improvement evaluation unit 300 and the output unit 400, respectively, and for the detailed contents thereof, see Figs. Since it is the same as described in detail with reference to 2, it will be omitted below.

Hereinafter, the present invention will be described in more detail through test examples. However, these test examples are provided for illustrative purposes only to help the understanding of the present invention, and the scope and scope of the present invention are not limited by the following examples.

[Test Example 1] Significant difference comparison test with the existing elasticity index

The following experiment was performed to confirm that the skin elasticity measurement value (A) used in the skin elasticity improvement evaluation system according to an embodiment of the present invention represents a more accurate change in skin elasticity compared to the existing elasticity index.

For the experimental method, 36 subjects in their 20s and 10 subjects in their 50s were washed under constant temperature and humidity conditions (22±2℃, 45±5% RH) for 15 minutes. Skin elasticity was measured using a cutometer (Courage & Khazaka, Germany) 2mm probe to measure the elasticity of the subject's eyes, front cheeks, nasolabial folds, and forearms. In this case, the settings of 450 mbar, suction/relaxation 2s, and 3 cycles were used. After measuring the skin elasticity of the subject, as a result of statistical analysis by T-test, the p value was When it is less than 0.05, a significant difference is indicated, and the results are shown in FIGS. 4 and 5 .

As shown in FIG. 4 , it can be confirmed that there are parts that do not show a significant difference in the existing elasticity indicators R0 and R6 used in the cutometer sensor for each elasticity measurement part. Specifically, in the case of R0, there was no significant difference in the front of the cheek, and in the case of R6, there was no significant difference in all areas except the eye area.

However, as shown in FIG. 5 , when the skin elasticity measurement values (A=R0/R6) used in the calculation unit 200 according to the present invention were compared and analyzed under the same conditions, it was confirmed that significant differences were observed in all regions. could

As such, from the results of FIGS. 4 and 5, the skin elasticity measurement value (A) used in the calculation unit 200 according to the present invention shows a significant difference between the 20s and 50s in all parts of the facial skin and arm skin. It can be confirmed that the elasticity change can be more accurately represented compared to the existing elasticity index.

That is, the calculating unit 200 according to the present invention calculates the skin elasticity measurement value (A) from the total deformation (R0) and viscoelastic deformation rate (R6) of the skin corresponding to the existing elasticity index, and evaluates the improvement of skin elasticity The unit 300 may provide a more accurate and intuitive elasticity improvement evaluation result by evaluating the skin elasticity improvement degree using the skin elasticity measurement value (A).

[Test Example 2] Product elasticity improvement efficacy evaluation test

The following experiment was performed to confirm the skin elasticity improvement effect of the product through the skin elasticity measurement value (A) used in the skin elasticity improvement evaluation system according to an embodiment of the present invention.

For the experimental method, 10 subjects in their 40s and 50s were washed with an eye wash and then waited for 15 minutes under constant temperature and humidity conditions (22±2℃, 45±5% RH). The elasticity of the skin around the subject's eyes was measured using a cutometer (Courage & Khazaka, Germany) 2mm probe. In this case, the settings of 450 mbar, suction/relaxation 2s, and 3 cycles were used. The product to be evaluated for efficacy was applied to the measurement site twice a day for 28 days. After 28 days, skin elasticity was measured again, and as a result of statistical analysis by paired T-test, a significant difference was indicated when the p-value was less than 0.05, and the results are shown in FIG. 6 .

As shown in FIG. 6 , when the total deformation (R0) and viscoelastic deformation rate (R6) of the skin, which are the existing elasticity indicators, were analyzed, the viscoelastic deformation rate (R6) did not show a significant difference, and the total deformation of the skin (R0) ), a significant difference was observed, but the change rate before and after product application was significantly lower than the skin elasticity value (A) according to the present invention, indicating that it was difficult to intuitively confirm the elasticity improvement effect.

On the other hand, the skin elasticity measurement value (A) according to the present invention increased statistically significantly after application compared to before application of the product, and the rate of change was also found to be 5% or more, so that the skin elasticity improvement effect of the product can be confirmed more intuitively. there was.

100: skin elasticity measurement unit 200: calculation unit
300: skin elasticity improvement evaluation unit 400: output unit
S100: The skin elasticity measurement unit applies a certain negative pressure to the skin before and after application of the substance or product to evaluate the skin elasticity improvement effect, induces skin deformation, measures skin elasticity, and measures the total deformation (R0) and viscoelastic deformation rate of the skin ( Steps to derive R6)
S200: The calculation unit processes the total deformation (R0) and viscoelastic deformation rate (R6) of the skin before and after application of the substance or product derived in step S100 with a predetermined formula, respectively, to obtain the skin elasticity measurement value (A) before and after application of the substance or product step to calculate
S300: A step in which the skin elasticity improvement evaluation unit compares the skin elasticity measurement value (A) before and after application of the material or product calculated in step S200 to evaluate the skin elasticity improvement degree
S400: outputting the skin elasticity change evaluation result in step S300 by the output unit

Claims (12)

a skin elasticity measuring unit for measuring skin elasticity by inducing deformation of the skin by applying a certain negative pressure to the skin, and deriving a total deformation (R0) and viscoelastic deformation rate (R6) of the skin;
a calculation unit for calculating the skin elasticity measurement value (A) by processing the total deformation (R0) and viscoelastic deformation rate (R6) of the skin derived from the skin elasticity measurement unit by the following formula (1); and
As a skin elasticity improvement evaluation system for evaluating a candidate substance or candidate product for improving skin elasticity, including a skin elasticity improvement evaluation unit for evaluating the skin elasticity improvement degree using the skin elasticity measurement value (A) calculated by the calculation unit ,
The skin elasticity measurement unit,
Measure each skin elasticity of the skin before and after application of the candidate substance or candidate product for improving skin elasticity, and derive the total deformation (R0) and viscoelastic deformation rate (R6) of the skin,
The calculation unit,
The total deformation (R0) and viscoelastic strain (R6) of the skin before and after application of the candidate material or candidate product are treated with the following formula (1), respectively, to calculate the skin elasticity measurement value (A) before and after application of the candidate material or candidate product and
The skin elasticity improvement evaluation unit,
When the increase rate of the measured skin elasticity value (A) before and after application of the candidate substance or candidate product is 5% or more by comparing the measured value (A) of the skin elasticity before and after application of the candidate substance or candidate product, the candidate substance or candidate product is A skin elasticity improvement evaluation system for evaluating a candidate substance or candidate product for improving skin elasticity, which is evaluated as having a skin elasticity improvement effect.
A = R0/R6 = {Ue(Uv+Ue)}/Uv … … Formula (1)
Here, immediate deformation (Ue) represents the elastic deformation of the skin, viscoelastic contribution in deformation of skin (Uv) represents the viscous deformation of the skin, R0 is Uv+Ue, and R6 is Uv/Ue. According to claim 1, wherein the skin elasticity improvement evaluation unit,
A candidate substance or candidate for improving skin elasticity, characterized in that after statistical analysis of the skin elasticity measurement value (A) before and after application of the candidate substance or candidate product, the skin elasticity improvement effect of the candidate substance or candidate product is evaluated Skin elasticity improvement evaluation system for product evaluation. The method of claim 2, wherein the skin elasticity improvement evaluation unit,
The increase rate of the skin elasticity measurement value (A) before and after application of the candidate substance or candidate product is 5% or more, and the p of the result of statistical analysis of the skin elasticity measurement value (A) by the paired t-test method When the value is less than 0.05, the skin elasticity improvement evaluation system for the evaluation of the candidate material or candidate product for skin elasticity improvement, characterized in that the candidate material or candidate product is evaluated as having an effect of improving skin elasticity. The method of claim 1,
The negative pressure is 450mbar, skin elasticity improvement evaluation system for evaluation of a candidate material or candidate product for improving skin elasticity. The method of claim 1,
The candidate material is an artificial compound, a natural extract or a cosmetic, and the candidate product is a skin elasticity improvement evaluation system for evaluation of a candidate material or candidate product for improving skin elasticity, characterized in that the candidate product is a cosmetic. The method of claim 1,
The skin elasticity improvement evaluation system for evaluating a candidate substance or candidate product for improving skin elasticity, characterized in that it further comprises an output unit for outputting a skin elasticity improvement evaluation result in the skin elasticity improvement degree evaluation unit. (1) The skin elasticity measuring unit applies a certain negative pressure to the skin before and after the application of the candidate substance or candidate product for improving skin elasticity, respectively, to induce the deformation of the skin to measure the skin elasticity, and measure the total deformation (R0) and the viscoelastic deformation rate (R6) of the skin ) to derive;
(2) The calculation unit processes the total deformation (R0) and viscoelastic deformation rate (R6) of the skin before and after application of the candidate substance or candidate product derived in step (1) with the following formula (1), respectively, to process the candidate substance or candidate calculating a skin elasticity measurement value (A) before and after product application; and
(3) Skin elasticity improvement comprising the step of evaluating the improvement in skin elasticity by comparing the skin elasticity measurement value (A) before and after application of the candidate substance or candidate product calculated in step (2) by the skin elasticity improvement evaluation unit As a method for evaluating skin elasticity improvement for evaluation of candidate substances or candidate products,
The skin elasticity improvement evaluation unit of step (3),
When the increase rate of the skin elasticity measurement value (A) before and after application of the candidate material or candidate product is 5% or more, the candidate material or candidate product is evaluated as having an effect of improving skin elasticity, a candidate material for improving skin elasticity, or Method for evaluating skin elasticity improvement for evaluation of candidate products.
A = R0/R6 = {Ue(Uv+Ue)}/Uv … … Formula (1)
Here, immediate deformation (Ue) represents the elastic deformation of the skin, viscoelastic contribution in deformation of skin (Uv) represents the viscous deformation of the skin, R0 is Uv+Ue, and R6 is Uv/Ue. The method of claim 7, wherein in the step of evaluating the improvement in skin elasticity,
For the evaluation of a candidate substance or candidate product for improving skin elasticity, characterized in that it further comprises the step of statistically analyzing the skin elasticity measurement value (A) before and after application of the candidate substance or candidate product to confirm whether it has statistical significance Method for evaluating skin elasticity improvement. The method of claim 8, wherein in the step of evaluating the improvement of skin elasticity,
The increase rate of the skin elasticity measurement value (A) before and after application of the candidate substance or candidate product is 5% or more, and the p of the result of statistical analysis of the skin elasticity measurement value (A) by the paired t-test method When the value is less than 0.05, the skin elasticity improvement evaluation method for the evaluation of the candidate material or candidate product for improving skin elasticity, characterized in that the candidate material or candidate product is evaluated as having an effect of improving skin elasticity. 8. The method of claim 7,
Wherein the negative pressure is 450mbar, skin elasticity improvement evaluation method for evaluating a candidate material or candidate product for improving skin elasticity. 8. The method of claim 7,
The candidate material is an artificial compound, a natural extract, or a cosmetic, and the candidate product is a cosmetic, a method for evaluating skin elasticity improvement for evaluation of a candidate material or candidate product for skin elasticity improvement. 8. The method of claim 7,
(4) Skin elasticity improvement evaluation method for evaluating a candidate substance or candidate product for skin elasticity improvement, characterized in that it further comprises the step of outputting the skin elasticity improvement evaluation result in step (3) by the outputting unit .

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