KR102369697B1 - Bio sensing module, and system including the same - Google Patents

Abstract

The biosensing module according to an embodiment of the present invention is formed to pass through a substrate, and includes a plurality of moving holes and the plurality of moving holes constituting a path through which a user's sweat moves from the lower part of the substrate to the upper part of the substrate. A plurality of collection wells concavely formed so as to collect the user's sweat moved through the system and each of the plurality of collection wells are disposed in each of the plurality of collection wells, and at least one contained in the sweat in response to the collected sweat biosensors capable of sensing a component of

Description

A biosensing module, a biosensing device, and a biosensing system including the same {BIO SENSING MODULE, AND SYSTEM INCLUDING THE SAME}

The present invention relates to a biosensing module, a biosensing device, and a biosensing system including the same, and more particularly, it is possible to sense at least one component included in sweat by moving and collecting the sweat of a user on an upper portion of a substrate. It relates to a biosensing module, a biosensing device, and a biosensing system including the same.

Recently, as interest in smart healthcare technology increases, technologies for predicting and preventing diseases are being developed in earnest, going beyond the limits of past medical technologies to treat already-onset diseases.

In particular, a non-invasive method that uses samples such as blood, saliva, urine, and sweat collected from the human body for testing is in the spotlight, and a biomarker that can quickly and accurately test whether a disease occurs with a small amount of sample is in the spotlight. necessity is emerging.

(Patent Document 1) Japanese Unexamined Patent Publication No. 2008-504881 (2008.02.21)

The technical problem to be achieved by the present invention is to provide a biosensing module, a biosensing device, and a biosensing system including the same, capable of sensing at least one component included in sweat by moving and collecting the sweat of a user on an upper portion of a substrate will do

In the biosensing module according to an embodiment of the present invention, each of the plurality of movement holes is formed to pass through a substrate, and a plurality of movement holes constituting a path through which a user's sweat moves from a lower portion of the substrate to an upper portion of the substrate, the plurality of movement A plurality of collection wells concavely formed so as to collect the sweat of the user moved through the holes, and each of the plurality of collection wells are disposed in each of the plurality of collection wells, and at least contained in the sweat in response to the collected sweat Biosensors capable of sensing one component may be included.

In some embodiments, the plurality of movement holes and the plurality of collection wells may be formed in a repeating pattern on the substrate.

According to an embodiment, the biosensing module may further include an adhesive layer formed on a lower surface of the substrate to attach the biosensing module to the user's skin.

In some embodiments, holes corresponding to the plurality of moving holes may be formed in the adhesive layer.

In some embodiments, each of the biosensors may be disposed on a bottom surface of each of the plurality of collection wells.

According to an embodiment, the wall surfaces of the plurality of moving holes may be formed in a curved surface.

According to an embodiment, the plurality of moving holes may form a narrower path from the lower side to the upper side.

According to an embodiment, the wall surfaces of the plurality of collection wells may be formed to have a curved surface.

According to an embodiment, the plurality of collection wells may form a narrower path from an upper side to a lower side.

According to an embodiment, sweat that has moved through any one of the plurality of moving holes may be dispersed and collected in a plurality of collection wells adjacent to the one of the moving holes.

According to an embodiment, sweat that has moved through any one of the plurality of moving holes may be collected in at least four or more collection wells adjacent to the one of the moving holes.

According to an embodiment, the plurality of movement holes may be formed in all of the remaining regions of the substrate except for the region in which the plurality of collection wells are formed and the region in which the connection pattern connecting between the plurality of collection wells is formed.

According to an embodiment, each of the biosensors may change color in response to the collected sweat.

A biosensing device according to an embodiment of the present invention includes a plurality of biosensing modules capable of detecting different components included in a user's sweat, and each of the plurality of biosensing modules passes through a substrate. a plurality of moving holes constituting a path through which the user's sweat moves from the lower part of the substrate to the upper part of the substrate, and a plurality of collecting holes concavely formed to collect the sweat moved through the plurality of holes Wells and biosensors each disposed in each of the plurality of collection wells may include biosensors capable of sensing at least one component included in the sweat in response to the collected sweat.

The biosensing system according to an embodiment of the present invention obtains a biosensing module capable of detecting at least one component included in a user's sweat and an image regarding the color of the plurality of biosensing modules, and a user terminal capable of analyzing the sweat component based on the plurality of biosensing modules, each of which is formed to penetrate a substrate, and constitutes a path through which the sweat moves from a lower portion to an upper portion of the substrate. Moving holes, a plurality of collecting wells concavely formed to collect the sweat moved through the plurality of holes, and each of which is disposed in each of the plurality of collecting wells, reacts to the collected sweat Thus, it may include biosensors capable of sensing at least one component included in the sweat.

Methods and apparatuses according to an embodiment of the present invention sense sweat components by moving and collecting sweat of a user through a micropattern formed on the substrate to the upper part of the substrate, thereby quickly and accurately sensing sweat components even with a small amount of sweat. There is an effect that can be done.

In order to more fully understand the drawings recited in the Detailed Description, a brief description of each drawing is provided.
1 is a plan view of a biosensing module according to an embodiment of the present invention.
FIG. 2 is a cross-sectional view of the biosensing module shown in FIG. 1 according to an embodiment.
3 is a cross-sectional view of the biosensing module shown in FIG. 1 according to another embodiment.
4 is a plan view of a biosensing module according to another embodiment of the present invention.
5 is a plan view of a biosensing module according to another embodiment of the present invention.
6 is a plan view of a biosensing module according to another embodiment of the present invention.
7 is a schematic diagram of a biosensing system according to an embodiment of the present invention.

Since the technical spirit of the present invention can have various changes and can have various embodiments, specific embodiments are illustrated in the drawings and described in detail. However, this is not intended to limit the technical spirit of the present invention to specific embodiments, and it should be understood to include all changes, equivalents, or substitutes included in the scope of the technical spirit of the present invention.

In describing the technical idea of the present invention, if it is determined that a detailed description of a related known technology may unnecessarily obscure the subject matter of the present invention, the detailed description thereof will be omitted. In addition, numbers (eg, first, second, etc.) used in the description process of the present specification are only identification symbols for distinguishing one component from other components.

In addition, in this specification, when a component is referred to as “connected” or “connected” with another component, the component may be directly connected or directly connected to the other component, but in particular It should be understood that, unless there is a description to the contrary, it may be connected or connected through another element in the middle.

In addition, terms such as "~ unit", "~ group", "~ character", and "~ module" described in this specification mean a unit that processes at least one function or operation, which is a processor, a micro Processor (Micro Processor), Micro Controller (Micro Controller), CPU (Central Processing Unit), GPU (Graphics Processing Unit), APU (Accelerate Processor Unit), DSP (Drive Signal Processor), ASIC (Application Specific Integrated Circuit), FPGA (Field Programmable Gate Array), etc. may be implemented as hardware or software or a combination of hardware and software, and may be implemented in a form combined with a memory that stores data necessary for processing at least one function or operation. .

In addition, it is intended to clarify that the classification of the constituent parts in the present specification is merely a division for each main function that each constituent unit is responsible for. That is, two or more components to be described below may be combined into one component, or one component may be divided into two or more for each more subdivided function. In addition, each of the constituent units to be described below may additionally perform some or all of the functions of other constituent units in addition to the main function it is responsible for. Of course, it may be carried out by being dedicated to it.

1 is a plan view of a biosensing module according to an embodiment of the present invention. FIG. 2 is a cross-sectional view of the biosensing module shown in FIG. 1 according to an embodiment. 3 is a cross-sectional view of the biosensing module shown in FIG. 1 according to another embodiment.

Referring to FIG. 1 , the biosensing module 100A according to an embodiment of the present invention includes a substrate 10 , a plurality of movement holes MH1A to MH5A, a plurality of collection wells MW1A to MW4A, and a plurality of bio It may include sensors BM1A to BM4A.

In FIG. 1, only five moving holes, four collecting wells, and four biosensors are illustrated for convenience of explanation, and the number of moving holes, collecting wells, and biosensors can be variously changed.

Each of the plurality of moving holes MH1A to MH5A may be formed to pass through the substrate 10 . Each of the plurality of movement holes MH1A to MH5A may constitute a path through which sweat discharged from the user's skin contacting the biosensing module 100A may move from the lower part of the substrate 10 to the upper part.

Sweat discharged from the user's skin may move from the lower part of the substrate 10 to the upper part by the pressure discharged or the capillary pressure formed inside the plurality of movement holes MH1 to MH5A.

2 and 3 may show an example of a cross-section when the bio-sensing module 100A of FIG. 1 is cut into a first cross-section SEC A.

Referring to FIG. 2 together, the user's sweat may move upwards from the lower portion of the substrate 10 - 1 through the SWEAT PATH configured by the movement hole MH3A - 1 .

Referring to FIG. 3 together, the user's sweat may move upwards from the lower portion of the substrate 10-2 through the SWEAT PATH formed by the movement hole MH3A-2.

According to an exemplary embodiment, a wall surface (eg, SF1 ) of the moving hole MH3A-1 or MH3A-2 may be formed as a curved surface.

According to an embodiment, the moving hole MH3A-2 may form a narrow path from the lower side to the upper side.

In this case, the user's skin can be closely adhered to the wall formed by the curved surface of the movement hole (MH3A-2), and the user's sweat can effectively move through the shorter path (SWEAT PATH) of the movement hole (MH3A-2). there is.

According to an embodiment, a hydrophilic material may be formed on at least a portion of a wall surface (eg, SF1 ) of the movement hole MH3A-1 or MH3A-2.

Returning to FIG. 1 , each of the plurality of collection wells MW1A to MW4A may be concavely formed to collect sweat of a user moved through the plurality of movement holes MH1A to MH5A.

Referring to FIG. 2 together, each of the plurality of collection wells MW1A-1 and MW4A-1 may be formed in a concave shape in the substrate 10-1. According to an embodiment, a wall surface of each of the plurality of collection wells MW1A-1 and MW4A-1 may be formed in a planar shape.

The sweat of the user moved along the SWEAT PATH formed through the movement hole MH3A-1 passes through the upper surface of the substrate 10-1 and is collected in the concave collection well MW1A-1 or MW4A-1. can

Referring to FIG. 3 together, each of the plurality of collection wells MW1A-2 and MW4A-2 may be formed in a concave shape in the substrate 10-2. According to an embodiment, a wall surface (eg, SF2 ) of each of the plurality of collection wells MW1A-2 and MW4A-2 may be formed to have a curved surface.

According to an embodiment, the plurality of collection wells MW1A-2 and MW4A-2 may form a narrow path from top to bottom.

According to an embodiment, a hydrophilic material may be formed on at least a portion of a wall surface (eg, SF2) of each of the plurality of collection wells MW1A-1 and MW4A-1, or MW1A-2 and MW4A-2.

The user's sweat moved along the SWEAT PATH formed through the movement hole MH3A-2 passes through the upper surface of the substrate 10-2 to be collected in the concave collection well MW1A-2 or MW4A-2. can

Returning to Figure 1, each of the plurality of biosensors (BM1A ~ BM4A) is disposed in each of the plurality of collection wells (MW1A ~ MW4A), in response to the sweat collected in each of the plurality of collection wells (MW1A ~ MW4A) At least one component included may be sensed.

According to an embodiment, the plurality of biosensors BM1A to BM4A may be implemented as biomarkers.

According to an embodiment, the color of the plurality of biosensors BM1A to BM4A may change in response to at least one component of the collected sweat.

According to an embodiment, the plurality of biosensors BM1A to BM4A detects components such as glucose, lactate, cortisol, chloride, or urea contained in sweat. can sense

2 and 3 , according to an embodiment, each of the biosensors BM1A-1, BM4A-1, BM1A-2, BM4A-2 includes collection wells MW1A-1, MW4A-1, MW1A-2, MW4A-2) can be disposed on each floor surface.

Returning to FIG. 1 , sweat moved from the user's skin through any one of the plurality of moving holes (eg, MH3A) among the plurality of moving holes (MH1A to MH5A) is collected by a plurality of adjacent moving holes (eg, MH3A). The wells (eg, MW1A to MW4A) may be dispersed and collected.

According to an embodiment, sweat moved from the user's skin through any one of the plurality of moving holes MH1A to MH5A (eg, MH3A) is at least four or more adjacent to any one of the moving holes (eg, MH3A). The collection may be dispersed and collected in collection wells (eg, MW1A to MW4A).

According to an embodiment, the plurality of movement holes MH1A to MH5A and the plurality of collection wells MW1A to MW4A may be formed in a repeating pattern on the substrate 10 .

According to an embodiment, the size of each of the plurality of moving holes MH1A to MH5A may be formed to have a fine size capable of generating capillary pressure to sweat discharged from the user's skin.

1 to 3 , according to an embodiment, the bio-sensing module 100A is formed on the lower surface of the substrates 10, 10-1, and 10-2, and the bio-sensing module 100A is applied to the user's skin. Adhesive layers 20-1 and 20-2 to be attached may be further included.

Referring to FIG. 3 , when the lower surface of the substrate 10 - 2 is formed to have a curved surface, the adhesive layer 20 - 2 may also be formed along the curved surface.

In some embodiments, holes corresponding to the plurality of moving holes (eg, MH3A-1 or MH3A-2) may be formed in the adhesive layers 20 - 1 and 20 - 2 . In FIG. 2 , a spaced region between the adhesive layer 20 - 1 corresponding to each of the collection wells MW1A-1 and MW4A-1 may correspond to the hole. In FIG. 3 , a spaced region between the adhesive layer 20 - 2 corresponding to each of the collection wells MW1A-2 and MW4A-2 may correspond to a hole.

4 is a plan view of a biosensing module according to another embodiment of the present invention.

1 to 4 , the biosensing module 100B includes a plurality of moving holes MH1B to MH4B, a plurality of collection wells MW1B to MW9B, and a plurality of biosensors included in the biosensing module 100B. A component of the user's sweat may be sensed in the same manner as in the biosensing module 100A of FIG. 1 , except for the arrangement of the fields BM1B to BM9B and the shape of the plurality of collection wells MW1B to MW9B.

Unlike the biosensing module 100A of FIG. 1 , in the biosensing module 100B, the plurality of collection wells (eg, MW1B to MW9B) are located in different rows and different columns from the plurality of moving holes MH1B to MH4B. can be arranged accordingly.

Each of the plurality of movement holes (eg, MH1B) may be disposed between four collection wells (eg, MW1B, MW2B, MW4B, MW5B), and the sweat that has migrated through each of the plurality of movement holes (eg, MH1B) is It may be distributed and collected into four adjacent collection wells (eg, MW1B, MW2B, MW4B, MW5B).

According to an embodiment, each of the plurality of moving holes MH1B to MH4B may be implemented in various shapes of a circle, an ellipse, or a polygon.

5 is a plan view of a biosensing module according to another embodiment of the present invention.

Referring to FIG. 5 , in the biosensing module 100C according to another embodiment of the present invention, sweat moved through one movement hole (eg, MH1C) is horizontally or vertically adjacent to a plurality of collection wells (eg, , MW1C to MW3C, or MW4C to MW6C) can be arranged to be dispersed and collected.

6 is a plan view of a biosensing module according to another embodiment of the present invention.

Referring to FIG. 6 , in the biosensing module 100D according to another embodiment of the present invention, a region in which a plurality of collection wells MW1D to MW6D is formed and a connection connecting the plurality of collection wells MW1D to MW6D A movement hole (eg, MH1D) may be configured in all of the remaining regions of the substrate 10 except for the region where the pattern (eg, BR1D) is formed.

7 is a schematic diagram of a biosensing system according to an embodiment of the present invention.

Referring to FIG. 7 , the biosensing system 1000 may include a biosensing device 200 and a user terminal 300 .

The biosensing device 200 may include a plurality of biosensing modules 100-1 to 100-4 capable of detecting different components included in the user's sweat.

For example, the first biosensing module 100-1 senses a glucose component contained in the user's sweat, and the second biosensing module 100-2 senses a lactate component contained in the user's sweat, The 3rd biosensing module 100-3 may sense a cortisol component included in the user's sweat, and the fourth biosensing module 100-4 may sense a urea component included in the user's sweat.

According to an embodiment, the biosensing system 1000 may include any one of the biosensing modules 100 - 1 to 100 - 4 included in the biosensing device 200 and the user terminal 300 .

The user terminal 300 may acquire an image related to the color of the biosensing modules 100-1 to 100-4 or any one of the biosensing modules 100-1 to 100-4. The user terminal 300 may analyze a component of sweat based on the acquired image.

According to an embodiment, the user terminal 300 may be implemented as a terminal device (eg, a smart phone) capable of image capture and image processing.

According to an embodiment, the user terminal 300 may analyze a component of sweat by using an average value of color changes of the biosensors included in the biosensing modules 100-1 to 100-4.

According to another embodiment, the user terminal 300 detects a component of sweat based on the number of biosensors having a color change greater than or equal to a reference value among the biosensors included in the biosensing modules 100-1 to 100-4. can be analyzed.

As mentioned above, although the present invention has been described in detail with reference to a preferred embodiment, the present invention is not limited to the above embodiment, and various modifications and changes can be made by those skilled in the art within the technical spirit and scope of the present invention. This is possible.

10: substrate
100A~100D, 100-1~100-4 : Bio sensing module
200: bio-sensing device
300: user terminal
1000: biosensing system

Claims (15)

a plurality of moving holes each formed to pass through the substrate and constituting a path through which the sweat of the user moves from the lower part to the upper part of the substrate;
a plurality of collecting wells concavely formed to collect the sweat of the user moved through the plurality of moving holes; and
each of which is disposed on the bottom surface of each of the plurality of collection wells, and includes biosensors capable of sensing at least one component included in the sweat in response to the collected sweat,
The sweat of the user moves from the lower portion of the substrate to the upper portion of the substrate through the path configured in each of the plurality of movement holes, passes through the upper surface of the substrate, and is disposed on the bottom surface of each of the plurality of collection wells A biosensing module that moves to a biosensor.
According to claim 1,
The plurality of moving holes and the plurality of collection wells are
A bio-sensing module formed in a repeating pattern on the substrate.
According to claim 1,
The biosensing module is
The biosensing module further comprising an adhesive layer formed on the lower surface of the substrate to attach the biosensing module to the user's skin.
4. The method of claim 3,
In the adhesive layer,
Holes corresponding to the plurality of moving holes are formed, the biosensing module.
According to claim 1,
Each of the biosensors,
A biosensing module disposed on a bottom surface of each of the plurality of collection wells.
According to claim 1,
Walls of the plurality of moving holes,
A biosensing module that is formed in a curved surface.
According to claim 1,
The plurality of moving holes,
A biosensing module that forms a narrow path from the bottom to the top.
According to claim 1,
Walls of the plurality of collection wells,
A biosensing module formed in a curved surface.
According to claim 1,
A plurality of collection wells,
A biosensing module that forms a narrow path from top to bottom.
According to claim 1,
Sweat moving through any one of the plurality of moving holes is dispersed and collected in a plurality of collection wells adjacent to the one of the moving holes.
11. The method of claim 10,
Sweat moving through any one of the plurality of moving holes is collected in at least four or more collection wells adjacent to the one of the moving holes.
According to claim 1,
The plurality of moving holes,
The biosensing module is configured in all of the remaining regions of the substrate except for the region in which the plurality of collection wells are formed and the region in which the connection pattern connecting between the plurality of collection wells is formed.
According to claim 1,
Each of the biosensors,
A biosensing module that changes color in response to the collected sweat.
It includes a plurality of biosensing modules capable of detecting different components contained in the user's sweat,
Each of the plurality of biosensing modules,
a plurality of moving holes each formed to pass through the substrate and constituting a path through which the sweat of the user moves from the lower part to the upper part of the substrate;
a plurality of collecting wells concavely formed to collect the sweat moved through the plurality of holes; and
each of which is disposed on the bottom surface of each of the plurality of collection wells, and includes biosensors capable of sensing at least one component included in the sweat in response to the collected sweat,
The sweat of the user moves from the lower portion of the substrate to the upper portion of the substrate through the path configured in each of the plurality of movement holes, passes through the upper surface of the substrate, and is disposed on the bottom surface of each of the plurality of collection wells A biosensing device that moves to a biosensor.
a plurality of biosensing modules capable of detecting at least one component included in the user's sweat; and
and a user terminal capable of acquiring an image related to the color of the plurality of biosensing modules and analyzing the sweat component based on the acquired image,
Each of the plurality of biosensing modules,
a plurality of moving holes each formed to pass through the substrate and constituting a path through which the sweat moves from a lower portion to an upper portion of the substrate;
a plurality of collecting wells concavely formed to collect the sweat moved through the plurality of holes; and
each of which is disposed on the bottom surface of each of the plurality of collection wells, and includes biosensors capable of sensing at least one component included in the sweat in response to the collected sweat,
The sweat of the user moves from the lower portion of the substrate to the upper portion of the substrate through the path configured in each of the plurality of movement holes, passes through the upper surface of the substrate, and is disposed on the bottom surface of each of the plurality of collection wells A biosensing system moving to a biosensor.

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