KR102350517B1 - Skin permeation apparatus and method - Google Patents

Abstract

The present invention, a sensing unit for sensing information related to the skin; an energy supply unit for supplying energy to at least a portion of the skin so that the active ingredient penetrates into the skin; and a control unit for respectively controlling the energy supply unit for each of the plurality of regions using the sensed information so that the degree of energy supply is formed differently in the plurality of regions, wherein the energy supply unit is applied to the skin in a low frequency band. Ultrasound is applied, and the low frequency band is individually controlled for each of the plurality of regions.

Description

SKIN PERMEATION APPARATUS AND METHOD

The present invention relates to a skin penetrating device and a skin penetrating method for penetrating an active ingredient into the skin.

Human skin tissue is composed of stratum corneum, epidermis, dermis, and hypodermis, and its function is deteriorated by aging and ultraviolet rays. In order to prevent aging of the skin, and to maintain and improve elasticity, it is possible to cause biological changes in the skin by using an effective substance.

These methods include a method of causing passive diffusion by applying a substance to the skin surface and attaching a mask or patch, and a method of causing active diffusion using a microneedle or low-frequency ultrasound and high-frequency perforation device. The method for causing passive diffusion has a disadvantage in that the performance of the skin permeability of the effective substance is lowered, and to overcome this passive diffusion limitation, an active diffusion method using a physical skin permeation enhancement technique is presented.

Currently, Korean Patent Laid-Open No. 10-2014-0035133 proposes a high-frequency electroporation device that outputs a voltage compensated for according to the resistance of the skin, and research on a method for causing active diffusion is being actively conducted.

However, these methods for causing active diffusion do not diagnose the skin condition in detail. Therefore, in consideration of the skin condition or aging condition, a method for providing customized skin care to customers may be considered.

One object of the present invention is to provide a skin penetrating device and a skin penetrating method capable of providing customized skin care to a customer.

Another object of the present invention is to provide a skin penetrating device and a skin penetrating method capable of controlling the number of micropores according to time or specific conditions in a high-frequency perforating device. Another aspect is to provide a structural change of a handheld type for customized diagnosis and care of a low-frequency ultrasound apparatus.

In order to achieve the above object of the present invention, the skin penetration device according to an embodiment of the present invention supplies energy to at least a part of the skin so that a sensing unit for sensing skin-related information and an active ingredient penetrate the skin. and a control unit for controlling each of the energy supply units for each of the plurality of regions by using the sensed information so that the degree to which the energy is supplied is different from each other in the plurality of regions, wherein the energy supply unit includes the It includes a plurality of electrodes for transmitting skin energy, and the controller controls the plurality of electrodes to adjust the size of the plurality of regions.

In an embodiment, the plurality of regions each have a plurality of energy supply lines to be controlled separately. The control unit may be configured to control the energy supplied to the plurality of energy supply lines, respectively.

In an embodiment, the energy supply unit may be divided into the plurality of regions, and the control unit may control the intensity of the energy to adjust the number of perforations generated in the skin by the energy supply in the plurality of regions. .

In an embodiment, at least some of the plurality of regions have different sizes. The plurality of regions may be set according to the type of the active ingredient.

In an embodiment, the controller changes the number of the plurality of regions by using the sensed information.

In an embodiment, at least a part of the energy supply unit is formed to be detachable. The energy supply unit may include electrodes arranged in a matrix form, and the plurality of regions may be controlled based on columns and rows of the electrodes. The energy supply unit may include a skin patch unit attached to the skin, and a high frequency generator connected to the skin patch unit to apply a high frequency current to the skin.

In an embodiment, the energy supply unit includes a tip contacting the skin, and an ultrasound generator connected to the tip to apply ultrasound to the skin, and further comprising an injection unit for injecting the active ingredient into the skin do.

In an embodiment, the plurality of regions are divided into a first region and a second region, the first region and the second region are individually controlled by the controller, and the first region and the second region have the same size Alternatively, it may be set to one size among different sizes.

In an embodiment, a frequency band and a band time of the first region and the second region may be determined according to the sensed information.

In an embodiment, the sensing unit includes a plurality of sensors to respectively sense the skin-related information in the plurality of areas. The skin-related information may include at least one of weight, age, skin condition, and efficacy patterns of active ingredients. The skin condition may include at least one of a change in skin resistance, a change in skin moisture, and a change in elasticity in a region currently being operated among the plurality of regions.

In addition, the present invention, the step of sensing information related to the skin, and using the information, determining a control method for each of a plurality of areas with respect to the energy supply unit for supplying energy to at least a part of the skin, the active ingredient; By controlling the energy supply unit for each of the plurality of regions by the determined control method to promote absorption of Disclosed is a skin penetration method comprising the step of injecting a component.

In an embodiment, the generating or deforming step may be a step of generating the perforation by passing a current through the electrodes in contact with the skin. Alternatively, the generating or deforming step may be a step of transforming the lipid tissue by applying ultrasound to the skin.

In an embodiment, the skin penetration method includes the step of notifying the information related to the sensed skin or the determined control method to the outside.

In an embodiment, the information related to the skin includes at least one of a degree of aging, a change in skin resistance, a change in moisture and elasticity of the skin, and an efficacy pattern of an active ingredient.

According to the skin penetrating device and skin penetrating method according to the present invention configured as described above, the number of perforations (or micropores) generated according to time/specific conditions is adjusted to control body weight, age, skin condition, and efficacy of active ingredients Personalizing according to patterns, etc. becomes possible.

In addition, according to the present invention, since the energy supply for skin perforation is controlled for each area by classifying the skin in detail, skin care can be tailored to each part of the skin.

In addition, according to the present invention, it is possible to increase the haptic effect of the customer by detecting the skin condition, providing skin care advice to the customer, providing the maximum effect using existing cosmetics, and providing information such as the absorption rate of the product.

1 is a conceptual diagram illustrating a skin penetration method according to an embodiment of the present invention.
Figure 2 is a flow chart showing the sequence of the skin penetration method of Figure 1.
3 and 4 are a perspective view and a partially enlarged view showing an embodiment of the skin penetration device of the present invention.
5 and 6 are a perspective view and a partial enlarged view showing another embodiment of the skin penetration device of the present invention.

Hereinafter, a skin penetrating device and a skin penetrating method according to a preferred embodiment of the present invention will be described in detail with reference to the accompanying drawings. In the present specification, even in different embodiments, the same and similar reference numerals are assigned to the same and similar components, and the description is replaced with the first description.

1 is a conceptual diagram illustrating a skin penetration method according to an embodiment of the present invention, and FIG. 2 is a flowchart illustrating the procedure of the skin penetration method of FIG. 1 .

Referring to the drawings, in the skin penetration method according to the present invention, first, the step of sensing information related to the skin is performed (S110).

Here, the sensing of information may be performed through the sensing unit 110 provided in the skin penetrating device 100 as shown in FIG. 1 . The sensing unit 110 may be, for example, a camera, a skin resistance measuring sensor, or an optical sensor. In this case, the information related to the skin includes, for example, at least one of a degree of aging, a change in skin resistance, a change in moisture and elasticity of the skin, and an efficacy pattern of an active ingredient.

More specifically, the camera may photograph the skin, and the controller 130 may sense the degree of aging, changes in moisture and elasticity of the skin, and the like by analyzing the captured image. As another example, a skin resistance measurement sensor may sense the change in skin resistance, or an optical sensor may sense an efficacy pattern of the active ingredient.

In addition, the sensing of information in the skin penetration device 100 according to the present invention may be made in response to a control command applied through various methods.

The control command may be applied by a voice command applied through the user's voice or by a user manipulation with respect to a user input unit (not shown). In this case, any method may be employed as long as the user input unit is a tactile manner in which the user operates while feeling a tactile feeling, such as a touch or push.

Furthermore, the control command for sensing the information is based on an image capturing request signal received from at least one external electronic device (eg, a remote control device or a smart phone) paired with the skin penetration device 100 according to the present invention. may be applicable.

like this. The controller 130 may perform sensing of skin-related information in response to the user's input.

Meanwhile, when information is sensed through the sensing unit 110 , the control unit 130 may store the sensed information in a memory. For example, an image captured by the camera may be stored in the memory. In this case, the controller 130 may store the captured image in the memory only when there is a request to store the captured image.

The skin penetrating device 100 according to the present invention may inform the outside of information related to the sensed skin. The step of notifying the outside may be, for example, a step of recommending skin care while notifying the user's current skin condition. Following the informing step, the skin penetrating device 100 may receive a control command for performing skin care. That is, the steps to be described below may be performed only when the control command is received. However, the present invention is not necessarily limited thereto, and the step of informing the outside or receiving a control command may be omitted in the skin penetration method according to the present invention.

Thereafter, the control unit 130 analyzes the sensed information according to a preset method. In addition, by analyzing the sensed information, a step (S120) of determining a control method for each of a plurality of regions with respect to the energy supply unit for puncturing at least a part of the skin is performed.

The skin penetrating device 100 according to the present invention may be formed to perform different treatments for each of the plurality of regions 151 and 152 as shown in FIG. 1 . In this case, the control unit 130 uses the sensed information so that the perforations of the skin are formed differently in the plurality of areas 151 and 152, respectively, to the energy supply unit for each of the plurality of areas 151 and 152, respectively. control

More specifically, the energy supply unit 120 of the skin penetrating device is divided into the plurality of regions 151 and 152, and the energy applied for perforation is individually added to the plurality of regions 151 and 152 to be controlled separately. can be The energy supply unit 120 is configured to perforate at least a portion of the skin so that the active ingredient penetrates into the skin. In addition, the energy supply unit may be divided into the plurality of regions 151 and 152 , and each of the plurality of regions 151 and 152 may include a plurality of energy supply lines to be separately controlled.

Meanwhile, the control unit 130 is configured to control the energy supplied to the plurality of energy supply lines, respectively. For this example, the controller 130 may control the intensity of the energy to adjust the number of the perforations in the plurality of regions 151 and 152 .

As a more specific example, the energy supply unit 120 may have a structure in which the perforation is generated by passing a current through the electrodes in contact with the skin. In this case, the intensity of the current is individually controlled for each of the plurality of regions 151 and 152 . As another example, the time for applying the current may be individually controlled for each of the plurality of regions 151 and 152 . In this case, a case in which no current is applied may be included, and therefore, no current may be applied to at least some of the plurality of regions 151 and 152 .

Alternatively, the energy supply unit 120 may be formed to apply ultrasound of a low frequency band to the skin to modify the lipid tissue of the stratum corneum of the skin to improve the permeability of the skin. More specifically, the frequency band of the ultrasonic wave may be individually controlled for each of the plurality of regions 151 and 152 , or the application time of the ultrasonic wave may be individually controlled for each of the plurality of regions 151 and 152 . Even in this case, a case in which no ultrasonic wave is applied may be included, and accordingly, ultrasonic wave may not be applied to at least some of the plurality of regions 151 and 152 .

Meanwhile, the determined control method may be notified to the outside. As such, the method of notifying to the outside may be output in the form of voice information or visual information.

Next, the step (S130) of creating a perforation in the skin by controlling the energy supply unit for each of the plurality of regions 151 and 152 according to the determined control method to promote absorption of the active ingredient is performed.

For example, if the energy supply unit 120 generates perforations by passing a current through the electrodes, as shown in the figure, the energy supply unit 120 may be controlled such that the number of activated electrodes varies for each region. .

As a specific example, first, a plurality of electrodes are brought into contact with the skin by the user to form a perforation in the skin. The polarity of the voltage is controlled so that neighboring electrodes of the plurality of electrodes have different polarities for every cycle of the voltage applied to the electrodes. Through this, although perforation occurs in the skin, by varying the number of activated electrodes, the density of perforations may vary in each part of the skin.

As another example, a current of a first magnitude is applied to the first region and a current of a second magnitude different from the first magnitude is applied to the second region, and thus the diameter or depth of the perforations in the first region and the perforations in the second region may vary. As another example, the current may be applied to the first region for a first time, and to the second region for a second time different from the first time.

On the other hand, if the energy supply unit 120 applies low-frequency ultrasound to the skin to transform the lipid tissue in the stratum corneum of the skin to improve the permeability of the skin, the energy supply unit 120 determines whether or not the ultrasound is generated by each region. can be controlled. Through this, the permeability of the skin to the active ingredient in each part of the skin may be different.

Finally, the step of injecting the active ingredient into the generated perforation may proceed (S140).

The active ingredient may be, for example, cosmetics, drugs, emulsions, ampoules, etc., and penetrates into the skin through the perforations. Through this, it can be promoted for the skin to absorb the active ingredient. In this case, absorption is increased even using existing cosmetics, so that the maximum effect on the use of cosmetics can be imparted to the skin.

On the other hand, the skin penetration method of the present invention may include the step of detecting the absorption rate of the active ingredient, and notifying the user of the absorption rate according to a preset interval. Through this, the user's haptic effect can be increased.

According to the skin penetration method according to the present invention as described above, the shape or number of perforations (or micropores) generated in the skin according to time/specific conditions can be adjusted. Thus, the user can form a perforation suitable for a specific part of the skin. In addition, by generating a different frequency band of the low-frequency ultrasound for each region of the handheld tip, the permeability of the skin can be adjusted according to the time/specific condition of the skin. Accordingly, when a high-frequency current and a low-frequency ultrasound are supplied by dividing by regions according to the characteristics of the user, customized care is possible and the user's pain can be alleviated. Hereinafter, together with the accompanying drawings, look at the skin penetration devices to which the skin penetration method is applied. 3 and 4 are a perspective view and a partially enlarged view showing an embodiment of the skin penetration device of the present invention.

Referring to this figure, the body 240 of the skin penetrating device 200 includes a case, and the case provides a space in which various parts are mounted. A voltage for operating the energy supply unit 220 may be generated by the various components. In this case, the energy supply unit 220 functions to form a perforation in the skin through a high-frequency current, and may be referred to as a perforation unit.

For example, the main body 240 includes a power supply unit 241 , a voltage generator 242 , a control unit 230 , and an operation display unit 214 , and the components may be mounted inside the case.

The power supply unit 241 generates power for driving other components in the main body 240 . The power supply unit 241 may be a commercially available device for receiving home or industrial voltage, or a battery device for charging external power received through a DC adapter or the like.

The voltage generating unit 242 generates a voltage to be transmitted to the energy supply unit 220 . The voltage generator 242 needs to output a high frequency high voltage of 100 kHz or higher, and for this purpose, a process of amplifying a low voltage into a high voltage and converting the amplified high voltage into a high frequency may be performed. Accordingly, the voltage generator may be referred to as a high-frequency generator that generates high-frequency energy.

The control unit 230 controls the frequency, magnitude, polarity, generation time, etc. of the voltage generated by the voltage generator 242 to transmit an appropriate voltage to the energy supply unit 220 .

The control unit 230 may control the voltage so that the neighboring electrodes in the energy supply unit 220 have different polarities during one cycle of the voltage. For example, if the polarity of a voltage applied to an arbitrary electrode is positive, the polarity of another electrode disposed above, below, left, and right of the arbitrary electrode becomes negative. In this case, the electric current delivered into the skin tissue through the electrode forms a bipolar high-frequency current flow in the epidermis and dermal layer of the skin. Accordingly, it is possible to effectively form a uniform perforation at a desired depth in a short time with a small output.

The operation display unit 214 may be configured to inform the outside of information related to the skin sensed by the sensing unit 210 . As another example, the operation display unit 214 may be formed to inform the outside of the control method determined by the sensed information described above with reference to FIGS. 1 and 2 . As described above with reference to FIG. 1 , the sensing unit 210 may be, for example, a camera, a skin resistance measuring sensor, or an optical sensor.

The sensing unit 210 includes a plurality of sensors to sense the skin-related information in the plurality of regions 251 and 252, respectively.

The skin-related information may include at least one of weight, age, skin condition, and efficacy patterns of active ingredients. In addition, the skin condition may include at least one of a change in skin resistance, a change in skin moisture, and a change in elasticity in a region currently being operated among the plurality of regions 151 and 152 .

A plurality of sensors may be disposed in the sensing unit 210 to be spaced apart from each other to obtain information at various points on the skin. In this case, the plurality of sensors may be the same sensor or different types of sensors. For example, a plurality of optical sensors may be disposed to be spaced apart from each other, or a camera, a skin resistance measuring sensor, an optical sensor, etc. may be disposed to be spaced apart from each other.

Referring to FIG. 3 , the energy supply unit 220 includes a skin patch unit 221 and an electrode 222 .

The skin patch part 221 is a part attached to the skin, and may be a highly concentrated gel patch. The sensing unit 210 may be mounted on the skin patch unit 221 . In addition, the skin patch part 221 may be detachably mounted on the main body. That is, at least a part of the energy supply unit 220 is formed to be detachable.

In addition, the electrode 222 may be disposed on the skin patch part 221 to be a part in contact with the skin. The electrode 222 is composed of a plurality of electrodes, and serves to receive a voltage from the controller 230 and deliver it to the skin. In this case, the electrode 222 may have a needle shape with a very small diameter and a sharp tip at an acute angle.

The plurality of electrodes 222 may be arranged in a matrix form on a support substrate (not shown). Referring to FIG. 4 , the electrodes 222 are spaced apart from each other at a specific interval, and the specific interval may be set by a user.

The energy supply unit 220 is divided into a plurality of regions 251 , 252 , 253 , and 254 , and a current supply wiring (not shown) for supplying current to each of the plurality of regions 251 , 252 , 253 , 254 . this is provided For example, the current supply wiring is connected to each of the electrodes 222 through an X-direction line and a Y-direction line crossing each other, through which the controller 230 can individually control the electrodes 222 . let it be That is, the controller controls the current (or voltage) supplied to the electrodes 222 using energy supply lines having an X-direction line and a Y-direction line, respectively. In this case, the controller may control the magnitude of the current (or voltage) to adjust the number of the perforations in the plurality of regions 251 , 252 , 253 , and 254 .

As described above, since the electrodes 222 are individually controlled, the plurality of regions 251 , 252 , 253 , and 254 may be set by the controller 230 . In this case, the controller 230 sets the plurality of regions 251 , 252 , 253 , and 254 using sensed information (information according to individual skin characteristics).

In addition, since the electrodes 222 are individually controlled, the sizes of the plurality of regions 251 , 252 , 253 , and 254 may be varied. For example, at least some of the plurality of regions 251 , 252 , 253 , and 254 have different sizes. More specifically, when the power supplied to the first region 251 is 10W and the power supplied to the second region 252 is 30W, the first region 251 and the second region 252 are equal to each other. It can be set to a size or different sizes.

In this case, the sizes of the first region 251 and the second region 252 may be determined according to information sensed by the sensing unit. For this example, when there are many wrinkles near the first point and small wrinkles near the second point, the first area 251 covering the first point has a greater power than the second area 252 covering the second point can be given.

As another example, the plurality of regions 251 , 252 , 253 , and 254 may be set according to the type of active ingredient. More specifically, the region into which the first active ingredient is injected becomes the first region 251 , and the size of the first region is set according to the type of the first active ingredient. For this example, if the first active ingredient is a component for improving wrinkles around the eyes, the size of the first region 251 is set to suit the size of the eyes. In addition, the region into which the second active ingredient is injected becomes the second region 252 , and the size of the second region 252 is set according to the type of the second active ingredient. Since the second area 252 is a part outside the eye area, it becomes a component (for example, moisture) other than a component for improving wrinkles around the eyes, and the second area 252 is a large area outside the eye area. can be set. For injection of such an active ingredient, the skin penetrating device 200 may include an injection unit (not shown) for injecting the active ingredient into the generated perforation.

Also, the controller 230 may change the number of the plurality of regions by using the sensed information. As illustrated, when the control region is set to four regions, the plurality of regions may be controlled such that the first region 251 and the second region 252 are merged to change the control region into three regions. .

As another example, the plurality of regions 251 , 252 , 253 , and 254 may be controlled based on columns and rows of the electrodes. More specifically, the controller 230 controls the current supply in the row direction or the current supply in the column direction according to the row and column directions of all electrodes. In this case, the electrodes arranged in the row direction may be set as one region, and the electrodes arranged in the column direction may be set as another region. Also, the regions may be sequentially and alternately set according to time.

As another example, the controller 230 divides the whole into a plurality of regions 251 , 252 , 253 , and 254 , and then, in the divided regions, according to the row and column directions of the electrodes, a current in the row direction It is possible to control the supply or the current supply in the column direction.

As described above, in the present invention, ultrasound/high frequency energy is supplied in units of regions through detailed classification of skin as a diagnosis for individual skin characteristics, and through this, customized skin care can be implemented.

On the other hand, the skin penetration device described above may be implemented in other forms. 5 and 6 are perspective and partial enlarged views showing another embodiment of the skin penetration device of the present invention. In addition, in the embodiment to be described below, the same or similar reference numerals are assigned to the same or similar components as in the previous example, and the description is replaced with the first description.

Referring to the drawings, the energy supply unit includes an ultrasonic wave generator 322 . In this case, the ultrasonic generator 322 is combined with the tip 321 and the handpiece 323 to form a skin penetrating device for generating low-frequency ultrasonic waves. The tip 321 is a portion in contact with the skin, and a sensing unit 310 may be mounted to the tip 321 , and the position of the sensing unit 310 is not limited to a specific range. Referring to FIG. 6A , the sensing unit 310 may be located at the center of the regions. As another example, a plurality of sensing units 310 may be provided and positioned between the respective regions. As such, the number or position of the sensing units 310 may be modified in various forms according to the intention of the designer.

Also, the ultrasonic wave generator 322 is connected to the tip 321 to apply ultrasonic waves to the skin. More specifically, the ultrasonic generator 322 applies ultrasonic waves of a low frequency (20-50 kHz) band to the skin, thereby causing cavitation in the stratum corneum of the skin. Herein, such a cavity may be defined as an effect similar to the perforation described above. The skin delivery rate of cosmetics, drugs, etc. is increased by the cavity.

The tip 321 is divided into a plurality of regions 351 , 352 , and 353 , and for this purpose, the ultrasonic generator 322 is configured to include a frequency band, an additional time, and a region in the plurality of regions 351 , 352 , 353 . At least one of the sizes may be set differently. A supply line (not shown) to which the ultrasonic wave is supplied is provided in each of the plurality of regions 351 , 352 , and 353 . Through this, the plurality of regions 351 , 352 , and 353 can be individually controlled, and the controller can set the plurality of regions 351 , 352 , 353 using sensed information.

For example, in the same frequency band, the ultrasound application time of the first region 351 may be 10 minutes, and the application time of the second region 352 may be 30 minutes. As another example, the first region 351 and the second region 352 may be set to different frequency bands while varying the grant time.

In this case, the frequency band and time of the first region 351 , the second region 352 , and the third region 353 may be determined according to the information sensed by the sensing unit. As an example of this, when there are many wrinkles near the first point and small wrinkles near the second point, the first area 351 covering the first point is given larger than the second area 352 covering the second point The time may be set, and ultrasound having an appropriate frequency band is supplied according to the skin diagnosis condition.

As another example, the plurality of regions 351 , 352 , and 353 may be set according to the type of active ingredient. More specifically, the region into which the first active component is injected becomes the first region 351 , and the ultrasonic frequency band of the first region is set according to the type of the first active ingredient. For this example, if the first active ingredient is a component for improving wrinkles around the eyes, the frequency band of the first region 351 is set so that the active ingredient for improving wrinkles around the eyes is transmitted. Also, a region into which the second effective component is injected becomes the second region 352 , and a frequency band of the second region 352 is set according to the type of the second effective component. Since the second area 352 is a part outside the eye area, it becomes a component (for example, moisture) other than a component for improving wrinkles around the eyes, and the second area 352 is a large area outside the eye area. When the determination is made, the same frequency band may be set up to the third region 353 . For injection of such an active ingredient, the skin penetrating device 300 may include an injection unit (not shown) for injecting the active ingredient.

It is not limited to the configuration and method of the embodiments related to the skin penetrating device and the skin penetrating method as described above, and can be applied to other parts of the human body. In addition, all or part of each of the embodiments may be selectively combined so that various modifications may be made.

Claims (8)

a sensing unit for sensing skin-related information;
an energy supply unit for supplying energy to at least a part of the skin so that the active ingredient penetrates into the skin; and
and a control unit for controlling the energy supply unit for each of the plurality of regions by using the sensed information so that the degree to which the energy is supplied is formed differently in the plurality of regions,
The energy supply unit applies low-frequency ultrasound to the skin,
The plurality of regions is characterized in that the size is set according to the type of the active ingredient, the skin penetration device. According to claim 1,
The energy supply unit,
a tip contacting the skin; and
Connected to the tip, having an ultrasonic wave generator for applying ultrasonic waves to the skin, skin penetration device. According to claim 1,
The skin penetrating device, characterized in that at least some of the plurality of regions have the same size or different sizes. delete According to claim 1,
The control unit uses the sensed information to change the number of the plurality of areas, the skin penetration device. According to claim 1,
The plurality of regions are divided into a first region and a second region, the first region and the second region are individually controlled by the controller, and the first region and the second region have the same size or different sizes. A skin penetrating device that is set to one size. According to claim 1,
Skin penetration device, characterized in that it further comprises an injection unit for injecting the active ingredient into the skin. According to claim 1,
For each of the plurality of regions, the time for applying the low frequency band or the ultrasound is individually controlled, the skin penetration device.

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