KR102338231B1 - Improving keeping device for human body organization - Google Patents

Abstract

An improved human tissue preservation device according to the present invention comprises: a human tissue storage housing (110) having a cylindrical shape with an open upper part, having a female screw part (112) along the upper periphery of the inner circumferential surface, and storing human tissue; a foreign substance sorting member (120) having a hollow cylindrical shape, having a screen net (122) at the lower end to filter out foreign substances of a predetermined size or more, and sorting and separating solid foreign substances in a formalin aqueous solution (150); a pressing member (230) having a hollow cylindrical shape and including a pressing rod (232) provided with a first guide protrusion (232a) of a predetermined thickness along the upper periphery of the inner circumferential surface, a male screw part (234) embedded in the lower end of the pressing rod, and an aluminum (Al) film (236) provided at the lower end of the male screw part (234); and an aluminum film crushing member (140) including a main body (142) having a cross shape, a pressing plate (144) integrally provided at the lower end of the main body, and a plurality of wedge-shaped projections (144a) provided at equal intervals along the circumference of the bottom surface of the pressing plate. A second guide protrusion (232b) in the form of a semicircle for maintaining airtightness is provided integrally with the male screw part (234) at a predetermined vertical interval between the female screw part (112) of the human tissue storage housing (110) and the male screw part (234) of the pressing member (230) along the outer peripheral surface of the lower end of the pressing member (230). Accordingly, in the process of preserving human tissue, it is possible to reduce the occurrence of disorders of the central nervous system, shock, coma, and the like of a user who handles formalin.

Description

Improved keeping device for human body organization

The present invention relates to an improved apparatus for preserving human tissue, and in particular, reduces the occurrence of disorders of the central nervous system, shock, and coma by a user who handles formalin in the process of preserving human tissue, and the aluminum film crushing member is added to the aqueous formalin solution. It relates to an improved human tissue preservation apparatus configured to maintain an upright state in a received state and to maintain airtightness between a female threaded portion of a human tissue storage housing and a male threaded portion of a pressing member.

In general, biopsy not only occupies an important position in the field of diagnostic medicine, but also plays an important role in making the final decision on disease diagnosis made in clinical practice.

Pathological biopsy is a test in which disease name of disease is determined through microscopic observation by removing a diseased human tissue. Unlike other clinical pathological methods, biopsy is based on observing and judging tissue morphological changes.

Meanwhile, research institutes or medical institutions use tissue cells or organs cut from patients as test excision specimens to use as basic data for surgery or as research data.

The process of making a general test excision specimen consists of the steps of sampling, fixing, washing, embedding, sectioning, flattening, staining and encapsulation. By exposure to room temperature for a certain period of time, it refers to a process of creating and storing an environment similar to the environment inside the human body in order to prevent self-corruption of tissue cells or organs according to cellular changes.

The fixative used to store tissue cells or organs in this fixation step is acetic alcohol, Bouin's solution, Carnoy solution, formalin paraformaldehyde, or Zenker's solution is mainly used.

Among these fixatives, formalin is a colorless, toxic chemical, and is a trade name for an aqueous solution containing 37% (±0.5%) of formaldehyde (HCHO). This formalin is known to be about 5 times more than that of phenol, a toxic aromatic compound, and is mainly used as an anesthetic, insecticide, disinfectant, and preservative. When a person is exposed to such formalin for a long time, there is a problem of central nervous system disorders, shock and coma, leading to maximum death.

That is, in the prior art, formalin is poured into a cylindrical housing in a state where human tissue such as skin is put into the housing, and then the lid (cover) is closed to maintain the state in which the human tissue is immersed in the formalin solution, have.

In the case of such a method, formalin harmful to the human body is unwittingly scattered outside the storage box or comes into contact with the operator's hand in the process of preserving human tissue, and as described above, the user who handles formalin as described above causes disorders of the central nervous system, shock and coma. There was a problem that had a great adverse effect on health, such as causing a state, etc.

In order to solve this problem, the present applicant has applied for a human tissue preservation device on March 4, 2017 (Patent Registration No.: No. 10-1874304, hereinafter referred to as an earlier application).

1 to 4 , the previous application includes a human tissue receiving housing 110 , a foreign material sorting member 120 , a pressing member 130 , and an aluminum (Al) film crushing member 140 .

1 to 3 , the human tissue storage housing 110 accommodates human tissue such as tissue cells or organs cut from a patient, has a cylindrical shape with an open upper part, and has a female threaded portion along the inner peripheral surface upper periphery. (112) is formed.

2 to 4, the foreign material sorting member 120 is the pressing member 130 in the process of the formalin aqueous solution 150 stored in the pressing member 130 falling to the human tissue storage housing 110 inside or It is for sorting and separating foreign substances in the formalin aqueous solution, and has a hollow cylindrical shape and a screen net 122 for filtering out foreign substances of a certain size or more is attached at the bottom.

1 to 3, the pressing member 130 is for pressing the aluminum (Al) film crushing member 140 to drop the foreign material sorting member 120 side, the pressing rod 132 having a hollow cylindrical shape. ) and a male screw portion 134 extended to the lower end of the push bar, and an aluminum film 136 of a certain thickness is attached to the lower end of the male screw portion 134 .

2 to 4, the aluminum film crushing member 140 is integrally formed with a pressing plate 144 for rupturing the aluminum film 136 while in contact with the aluminum film 136 at the lower end of the body 142, the pressing plate ( A plurality of projections 144a having a wedge shape are formed along the circumference of the bottom surface of the 144 at equal intervals, and the wing portion 146 is integrally formed at the upper end of the body 142 as a radial shape.

Referring to FIGS. 3 and 4 for the previous application having the above configuration, a predetermined amount of formalin aqueous solution 150 is stored inside the pressing member 130 , and the aluminum film crushing member along the inner longitudinal direction of the pressing member 130 . (140) is established.

In addition, human tissue is accommodated inside the human tissue storage housing 110 , the foreign material sorting member 120 is fitted to the lower end of the pressing member 130 , and the female thread part 112 of the human tissue storage housing 110 . is screwed to the male screw portion 134 of the pressing member 130 .

In such a state, if you want to store human tissue through formalin, when you press and press the upper central part of the push rod 132, the aluminum film crushing member 140 moves downward, and the protrusion 144a is formed with the aluminum film 136 and It ruptures while in contact, and as a result, the aqueous formalin solution 150 stored in the pressing member 130 is poured down, and the human tissue that has been stored in the human tissue storage housing 110 via the foreign material sorting member 120 is It is immersed in this formalin aqueous solution (150).

At this time, the aluminum film crushing member 140 accommodated in the formalin aqueous solution 150 must always maintain an upright state inside the pressing member 130. In the case of the previous application, the aluminum film crushing member 140 is placed in an upright state There is no separate means for maintaining it.

Accordingly, when a nurse or a nursing assistant with relatively weak strength in the hospital presses and presses the upper central portion of the pressing rod 132, the aluminum film shredding member 140 moves downward at once and the aluminum film 136 through the protrusion 144a. ), it becomes difficult to rupture it while in contact with the pressing rod 132, causing the inconvenience of pressing the upper center part several times.

In addition, in the case of the previous application, the female screw part 112 provided at the upper end of the inner circumferential surface of the human tissue storage housing 110 has a structure in which the female screw part 112 is screwed to the male screw part 134 provided at the lower end of the pressing member 130, but the female screw part ( 112) and a separate means for maintaining the airtight (气密) between the male screw portion 134 is not provided.

Accordingly, there is a concern that harmful components of the aqueous formalin solution 150 may scatter to the outside through the space between the female screw part 112 and the male screw part 134 in the process of using the human tissue preservation device.

Republic of Korea Patent Publication No. 10-1568959 (2015. 11. 12) Republic of Korea Patent Publication No. 10-1150840 (June 13, 2012) Republic of Korea Patent Publication No. 10-1874304 (2018. 07. 06)

The present invention has been devised in view of the problems of the prior art, and an object of the present invention is to unwittingly cause an aqueous formalin solution harmful to the human body to scatter to the outside of the human tissue storage housing in the process of preserving human tissue, or An object of the present invention is to provide an improved apparatus for preserving human tissue that cannot be reached.

Another object of the present invention is to provide an improved human tissue preservation device that can reduce the occurrence of disorders of the central nervous system, shock and coma by a user who handles formalin in the process of preserving human tissue.

Another object of the present invention is to provide an improved human tissue preservation device capable of maintaining an upright state in a state in which the aluminum film crushing member is accommodated in a formalin aqueous solution.

Another object of the present invention is to provide an improved apparatus for preserving human tissue in which airtightness can be maintained between a female threaded part of a human tissue receiving housing and a male threaded part of a pressing member.

In order to achieve the above object of the present invention,

A human body tissue storage housing 110 having a cylindrical shape with an open upper part and having a female screw part 112 along the upper periphery of the inner circumferential surface, in which human tissue is accommodated;

As a hollow cylindrical shape, a screen net 122 is provided at the bottom to filter out foreign substances of a certain size or more, and a foreign substance sorting member for sorting and separating solid foreign substances in the formalin aqueous solution 150 ( 120);

A presser rod 232 provided with a first guide protrusion 232a of a certain thickness along the upper periphery of the inner circumferential surface as a hollow cylindrical shape, a male screw portion 234 extended to the lower end of the presser rod, and the male screw portion a pressing member 230 including an aluminum (Al) film 236 provided at the lower end of the 234; and

A main body 142 having a cross shape, a pressing plate 144 integrally provided at the lower end of the main body, and a plurality of wedge-shaped projections 144a provided at equal intervals along the circumference of the bottom surface of the pressing plate It is configured to include an aluminum film crushing member 140 comprising a,

To maintain airtightness between the female threaded portion 112 of the human tissue storage housing 110 and the male threaded portion 234 of the pressing member 230 along the lower outer peripheral surface of the pressing member 230 . There is provided an improved apparatus for preserving human tissue in which the second guide protrusion 232b in the form of a semicircle is provided integrally with the male screw part 234 at regular intervals up and down.

According to the improved human tissue preservation apparatus of the present invention as described above, there are the following effects.

First, in the process of preserving the aqueous formalin solution 150 by depositing the human tissue stored in the human tissue storage housing 110, the formalin aqueous solution 150 harmful to the human body is unwittingly scattered to the outside of the human tissue storage housing 110, or , out of reach of workers.

Second, it is possible to reduce the occurrence of disorders of the central nervous system, shock, coma, etc. for users who handle formalin in the process of preserving human tissue.

Third, the wing portion 146 of the aluminum film crushing member 140 is stably supported by the first guide protrusion 232a provided on the upper end of the inner circumferential surface of the pressing rod 232 and accommodated in the formalin aqueous solution 150 . It can also maintain an upright state.

Fourth, the female threaded portion 112 of the human tissue storage housing 110 by the second guide protrusion 232b provided along the periphery of the lower outer peripheral surface of the pressing member 230, and the male threaded portion 234 of the pressing member 230. Airtightness can be maintained between them.

1 is a perspective view showing a conventional human tissue preservation device;
Figure 2 is an exploded perspective view of the human tissue preservation device shown in Figure 1;
Figure 3 is an assembly cross-sectional view showing the human tissue preservation device shown in Figure 1;
Figure 4 is a partial cross-sectional view showing the use state of the human tissue preservation device shown in Figure 1;
5 is a perspective view showing an improved human tissue preservation apparatus according to an embodiment of the present invention;
6 is an exploded perspective view of the improved human tissue preservation device shown in FIG. 5;
7 is a longitudinal sectional view of the pressing member in the improved human tissue preservation apparatus shown in FIG. 5;
8 is an assembled cross-sectional view showing the improved human tissue preservation device shown in FIG. 5;
Fig. 9 is a partial cross-sectional view showing a state of use of the improved human tissue preservation apparatus shown in Fig. 5;

Hereinafter, an improved human tissue preservation apparatus according to a preferred embodiment of the present invention will be described in detail.

The terms or words used below should not be construed as being limited to a conventional or dictionary meaning, and based on the principle that the inventor can appropriately define the concept of a term to explain his invention in the best way. It should be interpreted as meaning and concept consistent with the technical idea of the present invention.

5 is a perspective view showing an improved human tissue preservation apparatus according to a preferred embodiment of the present invention, FIG. 6 is an exploded perspective view of the improved human tissue preservation apparatus shown in FIG. 5, and FIG. It is a longitudinal cross-sectional view of the pressing member in the improved human tissue preservation apparatus.

In addition, FIG. 8 is an assembled cross-sectional view illustrating the improved human tissue preservation apparatus shown in FIG. 5 , and FIG. 9 is a partial cross-sectional view illustrating a use state of the improved human tissue preservation apparatus illustrated in FIG. 5 .

In the present invention, the same reference numerals are assigned to the same components as in the prior art. 5 to 9, the improved human tissue preservation apparatus according to the present invention is largely a human tissue storage housing 110, a foreign material sorting member 120, a pressing member 230, an aluminum (Al) film crushing member ( 140) is included.

5 to 7 , the human tissue storage housing 110 accommodates human tissue (not shown) such as tissue cells or organs cut from a patient, and has a cylindrical shape with an open upper part, and has an upper circumference on the inner circumferential surface. A female screw portion 112 for screwing to the male screw portion 234 of the pressing member 230 to be described later is formed along the.

5 to 7 , the foreign material sorting member 120 is a human tissue storage housing 110 in which the aqueous formalin solution (150 in FIG. 8 ) stored in the pressing member 230 is passed through the foreign material sorting member 120 . It is for sorting and separating solid foreign substances in the pressing member 230 or in the formalin aqueous solution 150 in the process of falling to the A screen net 122 is attached.

The inner diameter of the foreign material sorting member 120 is formed slightly larger than the diameter of the lower end of the pressing member 230 to be described later so that the foreign material sorting member 120 is fitted to the lower end of the pressing member 230 .

5 to 7, the pressing member 230 is for pressing the aluminum film crushing member 140 accommodated therein and dropping it to the foreign material sorting member 120 side, and is made of a flexible synthetic resin material. be prepared

This pressing member 230 includes a pressing rod 232 having a hollow cylindrical shape, and a male screw portion 234 extended to the lower end of the pressing rod. In addition, an aluminum (Al) film 236 of a predetermined thickness is attached to the lower end of the male screw portion.

At this time, according to the present invention, by supporting the wing portion 146 of the aluminum film crushing member 140 to be described later along the upper circumference of the inner circumferential surface of the pressing rod 232 to maintain the aluminum film crushing member 140 in an upright state. The first guide protrusion 232a having a predetermined thickness is formed to protrude as one body.

In this case, the first guide protrusion 232a has a shape of a sanggwang-ha-gwan whose width gradually increases from the lower part to the upper part corresponding to the shape of the wing part 146 .

In addition, along the outer peripheral surface of the lower end of the pressing member 230 in contact with the aluminum (Al) film 236, the female screw portion 112 of the human tissue storage housing 110 and the male screw portion 234 of the pressing member 230. A second guide protrusion 232b in the form of a semicircle for maintaining airtightness therebetween is formed to protrude integrally with the male screw portion 234 at a predetermined upper and lower intervals.

At this time, the thickness of the second guide protrusion 232b protruding from the foreign material sorting member 120 so as not to interfere with the foreign substance sorting member 120 in the process of coupling the foreign substance sorting member 120 to the lower end of the pressing member 230 is a male screw part 234 . It is desirable not to exceed the thickness of

5 to 7 , the aluminum film crushing member 140 is in contact with the aluminum (Al) film 236 at the lower end of the main body 142 having a cross shape and is in contact with the pressing plate 144 for rupturing it. ) is formed as an integral body, and a plurality of wedge-shaped projections 144a are formed at equal intervals along the periphery of the bottom surface of the pressing plate to increase the rupture effect, and the upper end of the pressing member 230 is formed. The wing portion 146 for ascending and descending while in contact with the inner surface of the guide protrusion 232a is integrally formed in a radial form, and the wing portion 146 is curved with a certain curvature when viewed from the front. to provide This is to help concentrate the pressure in the center of the main body 142 when the user presses the upper end of the pressing member 230 by hand.

Hereinafter, the operation of the present invention having the above configuration will be described with reference to FIGS. 8 and 9 .

First, an aluminum film 236 is attached to the lower end of the pressing member 230 in a state in which an aqueous formalin solution 150 of a predetermined capacity is stored inside the pressing member 230 . In addition, the aluminum (Al) film crushing member 140 is installed along the inner longitudinal direction of the pressing member 230 .

At this time, the wing portion 146 of the aluminum film crushing member 140 is stably supported by the first guide protrusion 232a provided on the upper end of the inner circumferential surface of the pressing rod 232 and accommodated in the formalin aqueous solution 150 . It also maintains an upright position.

On the other hand, inside the human tissue storage housing 110, human tissue such as tissue cells or organs collected from a patient is accommodated. In such a state, when human tissue is to be stored through formalin, the foreign material sorting member 120 is fitted to the lower end of the pressing member 230 and the female screw portion 112 of the human tissue storage housing 110 is pressed by the pressing member. It is screw-coupled to the male screw part 234 of (230).

Accordingly, the female threaded portion 112 of the human tissue storage housing 110 by the second guide protrusion 232b provided along the lower outer peripheral surface of the pressing member 230, and the male threaded portion 234 of the pressing member 230. Airtightness is maintained between them.

When the upper center of the pressing rod 232 of the pressing member 230 is pressed and pressed in this state, the aluminum film 136 is formed by the projection 144a provided on the pressing plate 144 while the aluminum film crushing member 140 moves downward. ) and ruptures it while in contact with it, and accordingly, the formalin aqueous solution 150 stored in the pressing member 230 is poured down and is stored in the human tissue storage housing 110 via the foreign material sorting member 120. Human tissue is immersed in the formalin aqueous solution (150).

In this process, the solid foreign matter inside the pressing member 230 or in the formalin aqueous solution 150 is caught by the screen net 122, and after a certain time has elapsed, the female threaded part 112 of the human tissue storage housing 110 ) separated from the male screw part 234 of the pressing member 230 and the human tissue preserved by the formalin aqueous solution 150 is used as basic data for the operation or as research data.

According to the present invention in the process as described above, the formalin aqueous solution 150 that is harmful to the human body is unknowingly in the process of preserving the human tissue stored in the human tissue storage housing 110 by depositing the formalin aqueous solution 150 into the human tissue storage housing It does not scatter to the outside of the 110, or touch the hand of the operator.

Accordingly, it is possible to reduce the occurrence of disorders of the central nervous system, shock, coma, etc. for users who handle formalin in the process of preserving human tissues.

In addition, the wing portion 146 of the aluminum film crushing member 140 is stably supported by the first guide protrusion 232a provided on the upper end of the inner circumferential surface of the pressing rod 232 and accommodated in the formalin aqueous solution 150 . It also maintains an upright position.

In addition, the female threaded portion 112 of the human tissue storage housing 110 by the second guide protrusion 232b provided along the circumference of the lower outer peripheral surface of the pressing member 230, and the male threaded portion 234 of the pressing member 230. Airtightness is maintained between them.

As described above, the improved human tissue preservation apparatus according to the present invention has been described with reference to the illustrated drawings, but the present invention is not limited by the embodiments and drawings disclosed in the present specification, and various methods can be obtained by those skilled in the art within the scope of the technical spirit of the invention. Of course, variations can be made.

110: human tissue storage housing 112: female thread part
120: foreign material sorting member 122: screen net
230: pressing member 232: pressing rod
232a: first guide projection 232b: second guide projection
234: male thread part 236: aluminum film
140: aluminum film crushing member 142: body
144: press plate 146: wing part

Claims (1)

A human body tissue storage housing 110 having an open upper part and having a female screw part 112 along the upper periphery of the inner circumferential surface, in which human tissue is accommodated; As a hollow cylindrical shape, a screen net 122 for filtering out foreign substances of a certain size or larger is provided at the bottom, and a foreign substance sorting member for sorting and separating solid foreign substances in the formalin aqueous solution 150 ( 120) and; A press rod 232 having a hollow cylindrical shape, a male screw part 234 that is extended to the lower end of the press bar and screwed to the female thread part 112 of the human tissue storage housing 110, and the male a pressing member 230 including an aluminum (Al) film 236 provided at the lower end of the screw portion 234 and to which the foreign material sorting member 120 is coupled to the lower end thereof; A body 142 having a cross shape, and a pressing plate 144 integrally provided at the lower end of the body and rupturing the aluminum (Al) film 236 of the pressing member 230 while in contact with it; In the human body tissue preservation device comprising an aluminum film shredding member 140 including a plurality of wedge-shaped projections 144a provided at equal intervals along the circumference of the bottom surface of the pressing plate,
A first guide of a certain thickness for maintaining the aluminum film crushing member 140 in an upright state by supporting the wing portion 146 of the aluminum film crushing member 140 along the upper periphery of the inner circumferential surface of the pressing rod 232 . The protrusion (232a) is provided as one body,
To maintain airtightness between the female threaded portion 112 of the human tissue storage housing 110 and the male threaded portion 234 of the pressing member 230 along the circumference of the lower end of the pressing member 230 . A second guide protrusion 232b in the form of a semicircle for
The first guide protrusion 232a has a shape of a sanggwang lower gorge whose width gradually increases from the lower part to the upper part corresponding to the shape of the wing part 146. Human tissue preservation device.

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