KR102320066B1 - Service for patient-customized prescribing and managing Adverse drug reactions based on electronic prescription management server - Google Patents

Abstract

A method for managing prescriptions in an electronic prescription management server may comprise the steps of: receiving adverse reaction information of a patient through a user terminal; generating or updating adverse reaction history information based on the input adverse reaction information; generating adverse reaction notification information based on the adverse reaction history information to set a scope of disclosure; transmitting the generated adverse reaction history information to a hospital terminal and a terminal of pharmacy; receiving prescription information generated based on the adverse reaction notification information from the hospital terminal; receiving the prescription information generated based on the adverse reaction notification information from the hospital terminal; and transmitting the received prescription information as an electronic prescription to the terminal of the pharmacy and receiving the dispensing result. According to the present invention as described above, based on the adverse reaction drug, it is possible to give an alarm in advance for a drug which is expected to have an adverse drug reaction in the future, and if necessary, it is also possible to make a recommendation for a safe alternative drug.

Description

Electronic prescription-based patient-customized prescription and adverse reaction management service {Service for patient-customized prescribing and managing Adverse drug reactions based on electronic prescription management server}

The present invention relates to a prescription management method of an electronic prescription management server. More specifically, the present invention relates to an electronic prescription management method for preventing an adverse reaction caused by a drug in a patient.

Since the division of labor was implemented in July 2000, hospitals have printed prescriptions for submission to pharmacies in hard copy format and issued them to patients.

Recently, with the development of electronic communication services, more and more hospitals provide electronic prescriptions rather than paper-printed prescriptions.

As such, by providing an electronic prescription to a pharmacy through a communication network in the form of an electronic prescription, a patient can receive a prescription drug without having to have a paper prescription issued by the hospital, simply by visiting a pharmacy and performing identity authentication.

However, the conventional electronic prescription system provides a one-way information delivery in which a prescription issued by a hospital or clinic is extracted and dispensed at a pharmacy visited by the patient using an issuance code. Even if the hospital is notified about adverse drug reaction in advance, there may be a problem that drugs that may cause an adverse reaction by mistake of the hospital are included in the electronic prescription or cannot be verified when dispensing at the pharmacy.

In addition, since it is difficult for pharmacies to recognize the patient's adverse drug reaction, there may be a problem that the drug that causes the patient's adverse drug reaction is included in the replacement dispensing process.

These adverse drug reactions sometimes end with simple reactions, but there are cases where they can pose a serious risk to the patient's life, so an electronic prescription management system that considers adverse drug reactions is required.

Japanese Patent No. 5317783 (Registered on July 19, 2013)

An object of the present invention is to provide a prescription management method of an electronic prescription management server.

Specifically, an object of the present invention is to provide a prescription management method for transmitting an electronic prescription between a hospital and a pharmacy and transmitting the electronic prescription to a user terminal of a patient.

Another object of the present invention is to provide a prescription management method in consideration of adverse reactions of patients during the issuance of a prescription by a hospital and the manufacture of a pharmacy.

The prescription management method of the electronic prescription management server includes the steps of receiving adverse reaction information of a patient through a user terminal, generating or updating adverse reaction history information based on the input adverse reaction information, and based on the adverse reaction history information The method may include generating and transmitting adverse reaction notification information to a hospital terminal, and receiving prescription information generated based on the adverse reaction notification information from the hospital terminal.

In addition, when the patient requests the electronic prescription, the method may further include transmitting the electronic prescription for customer storage to the user terminal.

The method may further include transmitting an electronic prescription for submission to the pharmacy and receiving a dispensing result from the pharmacy when the patient requests the pharmacy through the patient terminal.

In addition, the method may further include the steps of confirming whether the electronic prescription is an alternative medicine based on the dispensing result, and transmitting information on the replacement medicine to the user terminal and the hospital terminal when the replacement medicine has occurred.

In addition, the generating and transmitting the adverse reaction notification information to the hospital terminal may generate the adverse reaction notification information based on the disclosure range set by the patient.

In addition, the step of generating or updating the adverse reaction history information includes the steps of analyzing the drug ingredient code based on the adverse reaction information to determine the drug component causing the adverse reaction and adverse reaction history information based on the determined drug ingredient The method may further include generating or updating the information, wherein the adverse reaction information includes at least one of the administered drug name (brand name), ingredient name, and prescription, and each adverse reaction symptom may be matched.

In addition, when the adverse reaction information is not registered during the half-life of the drug included in the past prescription, it may be determined that there is no adverse reaction to the drug and the step of updating the adverse reaction history information may be further included.

In addition, the method may further include predicting a component likely to have an adverse reaction in the patient based on the adverse reaction history information.

On the other hand, in the prescription management method of an electronic prescription system including a hospital terminal, a patient terminal, a pharmacy terminal, and an electronic prescription management server, the patient terminal receives the patient's adverse reaction information from the patient, and stores the input adverse reaction information as the prescription. transmitting to the management server, the prescription management server generating or updating adverse reaction history information based on the input adverse reaction information, the prescription management server generating adverse reaction notification information based on the adverse reaction history information and transmitting to the hospital terminal, the hospital terminal generating the patient's prescription information based on the transmitted adverse reaction notification information, and transmitting the generated prescription information to the electronic prescription management server. .

In addition, in the program stored in the computer-readable recording medium according to an embodiment of the present invention for achieving the above object, a program code for executing the above-described prescription management method may be recorded.

According to the present invention, it is possible to check the prescription of a hospital through the user terminal or to transmit the electronic prescription to a desired pharmacy, thereby providing high convenience to the user.

In addition, according to the present invention, the patient can easily identify the drug component causing his or her adverse reaction by inputting the prescribed drug and symptoms, and manage the drug component causing the adverse reaction.

In addition, according to the present invention, it is possible to reduce adverse reactions or side effects due to interaction with the drug currently being taken by using the adverse reaction history information.

In addition, based on the adverse reaction drug, it is possible to give an alarm in advance for a drug that is expected to have an adverse drug reaction in the future, and can also recommend a safe alternative drug if necessary.

1 is an exemplary view showing an electronic prescription system according to an embodiment of the present invention.
2 to 3 are flowcharts illustrating a prescription management method of an electronic prescription management server according to an embodiment of the present invention.
4 is an exemplary diagram illustrating a method of constructing a database of an electronic prescription management server according to an embodiment of the present invention.
5 is an exemplary diagram illustrating a method for determining safety of a prescription according to an embodiment of the present invention.
6 is a flowchart illustrating a prescription management method of an electronic prescription management server according to an embodiment of the present invention.
7 is a timing diagram illustrating a prescription management method of an electronic prescription system according to an embodiment of the present invention.

The following is merely illustrative of the principles of the invention. Therefore, those skilled in the art will be able to devise various devices which, although not explicitly described or shown herein, embody the principles of the present invention and are included within the spirit and scope of the present invention. In addition, it should be understood that all conditional terms and examples listed herein are, in principle, expressly intended only for the purpose of understanding the inventive concept and are not limited to the specifically enumerated embodiments and states as such. do.

The above-described objects, features and advantages will become more apparent through the following detailed description in relation to the accompanying drawings, and accordingly, those of ordinary skill in the art to which the present invention pertains can easily implement the technical idea of the present invention. There will be. In addition, in the description of the present invention, if it is determined that a detailed description of a known technology related to the present invention may unnecessarily obscure the gist of the present invention, the detailed description thereof will be omitted.

Hereinafter, various embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 is an exemplary view showing an electronic prescription system 1000 according to an embodiment of the present invention.

Referring to FIG. 1 , the electronic prescription system 1000 includes a user terminal 10 in which an application for managing an electronic prescription is installed, a hospital terminal 20 that issues an electronic prescription, and a pharmacy used for dispensing by receiving an electronic prescription. The terminal 30 and the electronic prescription management server 100 for delivering and managing the electronic prescription may be configured.

The patient may input his/her adverse reaction information through an application installed in the user terminal 10 and transmit it to the electronic prescription management server 100 . Here, the adverse reaction information may include at least one or more of the name of the drug administered, the name of the drug ingredient, and the prescription, and the symptoms of the adverse reaction may be matched to each other.

The electronic prescription management server 100 may generate adverse reaction notification information based on the adverse reaction information input from the user terminal 10 . In addition, when the patient visits the hospital or the patient requests it, the electronic prescription management server 100 may transmit adverse reaction notification information to the hospital terminal 20 . The doctor may transmit the adverse reaction information received through the hospital terminal 20 . A prescription may be issued with reference to the notification information and transmitted to the electronic prescription management server 100 .

In addition, the electronic prescription management server 100 may transmit an electronic prescription for customer storage to the user terminal 10 when the patient requests it. In addition, when the patient requests manufacturing, the electronic prescription management server 100 may transmit the electronic prescription for submission to the pharmacy terminal 30 of the corresponding pharmacy.

The pharmacy terminal 30 may prepare the medicine based on the electronic prescription for submission, and then transmit the manufacturing result to the electronic prescription management server 100 .

The electronic prescription management server 100 may transmit the fact of occurrence of the replacement medicine to the user terminal 10 and the hospital terminal 20 when the replacement medicine is generated based on the manufacturing result.

In addition, based on the adverse reaction notification information, it is possible to give an alarm in advance for a drug that is expected to have an adverse drug reaction in the future. Additional notifications may be provided.

In addition, if necessary, a safe alternative drug may be recommended. For example, with antibiotics or NSAIDs, these services are possible.

More specifically, since antibiotics and NSAIDs are of various types, it can be recommended as more suitable or less likely to cause adverse reactions depending on the patient's condition. In the case of antibiotics, there are penicillin series, and depending on the patient's condition, for example, if the kidneys are not good, we can recommend an alternative drug except for a specific antibiotic.

In addition, there are various types of analgesics so that suitable ingredients can be prescribed according to the patient's condition.

Hereinafter, a prescription management method of the electronic prescription management server 100 will be described in more detail with reference to FIGS. 2 to 4 .

2 to 4 are flowcharts illustrating an electronic prescription management method of the electronic prescription management server 100 according to an embodiment of the present invention.

Referring to FIG. 2 , the electronic prescription management server 100 may receive adverse reaction information input through the user terminal 10 ( S100 ). Here, the adverse reaction information includes at least one of a drug name, an ingredient name, and a prescription administered by a patient in the past, and may also include past adverse reaction symptoms.

In addition, the adverse reaction information may match the patient's user information with the drug information taken, and the user information may include physical information such as the patient's height, weight, gender, and age, or other information such as an underlying disease and pregnancy status. In addition, the information about the drug taken by the patient is information about the drug the patient is currently taking, and may include at least one of a drug name, an ingredient name, a dosage, a number of doses, and a prescription.

The electronic prescription management server 100 may generate or update adverse reaction history information based on the received adverse reaction information (S200). Here, the adverse reaction history information may include drug ingredients, drug names, drug codes, ingredient codes, symptoms, etc. that may cause an adverse reaction in the patient. The step (S200) will be described with reference to FIGS. 3 and 4 .

Referring to FIG. 3 , the electronic prescription management server 100 may determine the drug component causing the adverse reaction by analyzing the drug ingredient code based on the adverse reaction information ( S210 ). First, the electronic prescription management server 100 may configure a database divided by drug component. For example, as shown in FIG. 4 , the electronic prescription management server 100 classifies whether a drug has a compound component based on the first 4 digits of the component code of the generic drug, and if it is a single component, stores it as a single component, and In the case of ingredients, they are further classified by related ingredients.

In this case, the database may build and store the relation between the related components as a series link. Specifically, the series link can be defined as a relationship between series components with a possibility of an adverse reaction even if they are not identical components by configuring the series link as a series link through comparison of the patient's similarity and the history of adverse reactions.

In addition, the electronic prescription management server 100 may classify and store pregnant women's precautions and series-specific precautions for each component.

That is, the electronic prescription management server 100 may configure the database by classifying medicines into single ingredients, complex-related ingredients, prohibited drugs for pregnant women, and precautionary drugs for each series in advance based on the ingredient code.

Thereafter, the electronic prescription management server 100 compares the adverse reaction information about the drug with the database divided by drug component, extracts the component code causing the adverse reaction, and provides prescription guidance by using this. For example, if the adverse reaction information includes a drug name and a corresponding adverse reaction symptom, the electronic prescription management server 100 checks the main ingredient code based on the drug name, and analyzes the main ingredient code to determine whether the drug is a single ingredient. It can be determined whether or not it is a complex component.

In the case of a single ingredient, the electronic prescription management server 100 may determine the corresponding ingredient as the ingredient causing the patient's adverse reaction.

When the corresponding drug is a complex ingredient, the electronic prescription management server 100 determines a related ingredient based on the patient's adverse reaction symptoms among the related ingredients linked to the complex ingredient on the database, and detects abnormality of the drug containing the related ingredients. It can be judged by the set of drugs that cause the reaction.

Therefore, the notification of an adverse reaction can be generated using a set of drugs of various complex components including a series component composed of a relationship between related components and a related component.

In addition, when there are multiple prescriptions of a complex component through the user's prescription history and an adverse reaction occurs, a common related component may be determined as the cause of the adverse reaction. In this case, the prescription history further considers the half-life of the prescribed drug, and it is also possible to more clearly determine the component of the adverse reaction by excluding the case where the time of occurrence of the drug effect has passed based on the half-life of the common ingredients.

As another example, when the body information matched with the adverse reaction information includes information on chronic diseases such as hypertension and diabetes and characteristic information such as pregnancy status, the electronic prescription management server 100 controls hypertension and pregnant women's prohibited drugs and cautions in the database. You can check the ingredients.

Next, the electronic prescription management server 100 may generate or update adverse reaction history information based on the drug component determined as the cause of the patient's adverse reaction (S220). Specifically, the electronic prescription management server 100 may generate or update adverse reaction history information by matching the corresponding drug ingredient with the drug containing the drug ingredient and the patient's symptoms.

In addition, the electronic prescription management server 100 may generate or update adverse reaction history information by matching prohibited drugs, cautionary ingredients, and drugs including the corresponding cautionary ingredients according to body information.

In addition, the electronic prescription management server 100 may generate or update adverse reaction history information including information about the drug currently being taken.

In this way, the patient can easily identify the drug component causing his or her adverse reaction by inputting the prescribed drug and symptoms, and can manage the drug component causing the adverse reaction.

Referring back to FIG. 3 , the electronic prescription management server 100 may generate adverse reaction notification information based on the adverse reaction history information ( S300 ). Here, the adverse reaction notification information may include some or all of the adverse reaction history information.

Specifically, the electronic prescription management server 100 may generate abnormal reaction notification information based on the disclosure range set by the patient. Here, the disclosure range is a set value that determines the range to be included in the adverse reaction notification information among the adverse reaction history information, and may include the disclosure range of adverse reaction components, adverse reaction symptoms, etc., and may be input through the user terminal 10 . have. Through this, the patient can proactively select the exposure range of adverse drug information, thereby protecting the patient's privacy.

In addition, the electronic prescription management server 100 may transmit to the hospital terminal 20 (S400). Specifically, when a patient visits or requests a hospital, the electronic prescription management server 100 may transmit abnormal reaction notification information to the hospital terminal 20 of the hospital.

For example, when it is determined that the patient has visited the hospital based on the location information of the user terminal 10 , the electronic prescription management server 100 transmits the patient's adverse reaction notification information to the hospital terminal 20 of the corresponding hospital. can

The electronic prescription management server 100 may receive prescription information generated based on the abnormal reaction notification information from the hospital terminal 20 (S500). Here, the prescription information means text included in the prescription, which will be described in detail later with reference to FIG. 5 .

In addition, when the patient requests the electronic prescription, the electronic prescription management server 100 may transmit the electronic prescription for customer storage to the user terminal 10 ( S600 ). Specifically, the electronic prescription management server 100 may determine whether the corresponding electronic prescription is safe based on the abnormal reaction history information of the corresponding customer, match the prescription state information, and transmit it to the user terminal 10 . Here, the prescription status information is information indicating whether the electronic prescription is safe for an adverse reaction, for example, information indicating safety of an adverse reaction, caution for adverse reaction, risk of pregnant women, and the like.

In this regard, it will be described with reference to FIG. 5 .

Referring to FIG. 5 , the electronic prescription management server 100 determines the presence or absence of a single ingredient by using the first four digits of the main ingredient code of the drug included in the electronic prescription, and compares it with the database to determine the ingredient, and if the ingredient is a pregnant woman It is possible to determine whether it is an ingredient or an ingredient of a caution drug by class. After determining the ingredients, the electronic prescription management server 100 may compare the adverse reaction history information of the patient with the determined ingredients to determine whether the electronic prescription is safe for the patient. In addition, the electronic prescription management server 100 may generate prescription state information according to the safety determination result, match the electronic prescription with the corresponding electronic prescription, and transmit it to the user terminal 10 .

Through this, the patient can easily check whether his prescription is safe from adverse reactions.

In addition, it is possible to analyze the relationship with the drug name written in the prescription by mapping the information on the KD (Korea Drug) coded drug item other than the main ingredient code with the main ingredient code.

Furthermore, through the ATC (Anatomical Therapeutic Chemical) code, the chemical properties are extracted according to the organ or system where the drug acts, and the direct anatomical features that cause side effects according to the component of the drug are derived through this, and the organ of the side effect. It is also possible to analyze adverse reactions and component histories according to

In addition, the electronic prescription management server 100 may transmit the electronic prescription for submission to the pharmacy terminal 30 (S700). Specifically, when a patient requests manufacturing to a pharmacy through the user terminal 10 or a patient visits a pharmacy, the electronic prescription management server 100 transmits the electronic prescription for submission to the pharmacy terminal 30 of the pharmacy. have. At this time, the electronic prescription management server 100 may also transmit abnormal reaction notification information. Through this, the pharmacist can perform alternative preparation by referring to the patient's adverse reaction notification information, thereby minimizing the prescription of drugs containing ingredients that cause adverse reactions.

The electronic prescription management server 100 may receive the dispensing result from the pharmacy terminal 30 (S800). Here, the preparation result may include a drug manufactured by a pharmacist and a component of the drug.

The electronic prescription management server 100 may check whether the electronic prescription is alternatively prepared based on the dispensing result (S900). Specifically, the electronic prescription management server 100 may compare the dispensing result with the corresponding electronic prescription to confirm whether or not an alternative dispensing is present. If an alternative preparation occurs, safety may be confirmed based on the adverse reaction history information.

In addition, when a substitute dispensing occurs, the electronic prescription management server 100 may transmit the substitute dispensing information to the user terminal 10 and the hospital terminal 20 (S1000). Here, the alternative preparation information may include the name of the alternatively prepared drug, ingredients, and the like, and may also include information on the state of the alternative preparation. Here, the status information of the alternative preparation is information indicating whether there is safety of an adverse reaction according to the corresponding alternative preparation, and may be information indicating, for example, safety of adverse reaction, caution of adverse reaction, risk of pregnant women, and the like.

Next, an additional prescription management method of the electronic prescription management server 100 will be described with reference to FIG. 4 .

Referring to FIG. 4 , the electronic prescription management server 100 may predict the extinction time of the drug effect based on the half-life of the drug included in the patient's past prescription and update the adverse reaction history information (S41).

Specifically, the electronic prescription management server 100 learns the correlation between body information (eg, weight, age, sex, etc.) affecting the half-life and the half-life of the component, and is applied to the learned neural network to calculate the weight of the half-life. Weights can be calculated by inputting ingredients and body information of drugs included in past prescriptions.

In addition, the electronic prescription management server 100 may calculate the expected half-life by applying a weight to the half-life of the corresponding component.

In addition, when adverse reaction information is not registered during the calculated expected half-life of a previously prescribed drug, the electronic prescription management server 100 determines that the patient does not have an adverse reaction to the drug or a component included in the drug and abnormal Reaction history information can be updated. In this case, the electronic prescription management server 100 may additionally check whether the user has an adverse reaction to the corresponding drug through the user terminal 10 , and then update the adverse reaction history information.

In addition, the electronic prescription management server 100 may predict a component that is likely to cause an adverse reaction in the patient based on the adverse reaction history information (S42).

Specifically, the electronic prescription management server 100 learns the correlation between drug components and adverse reaction symptoms based on the adverse reaction history information of several patients, and the possibility of occurrence of an adverse reaction in the patient based on the adverse reaction history information of the patient This high component can be predicted.

For example, the electronic prescription management server 100 uses the adverse reaction history information of several patients as learning data to learn the correlation between the drug component and the adverse reaction symptom, and a neural network to predict the component with a high probability of occurrence of the patient's adverse reaction. can learn In addition, the electronic prescription management server 100 may predict a component with a high probability of occurrence of an adverse reaction by inputting adverse reaction history information to the neural network.

In addition, the electronic prescription management server 100 compares the existing component that causes the patient's adverse reaction included in the adverse reaction history information with several other components and, when the similarity exceeds the reference value, sets the component to the patient's abnormality. It can be predicted as a component with a high probability of occurrence of a reaction.

In addition, the electronic prescription management server 100 may provide a warning about a component predicted to have a high probability of occurrence of an adverse reaction to the user through the user terminal 10 . For example, when a component predicted to have a high probability of occurrence of an adverse reaction is included in the prescription or included in the manufacturing result, the electronic prescription management server 100 may provide a warning pop-up window to the user terminal 10 .

Through this, the patient can be safe from adverse drug reactions caused by substitutes or dispensing errors.

Hereinafter, a prescription management method of the electronic prescription system 1000 will be described with reference to FIG. 5 .

5 is a timing diagram illustrating a prescription management method of the electronic prescription system 1000 .

Referring to FIG. 5 , the user terminal 10 may receive adverse reaction information from the patient (S501) and transmit the received adverse reaction information to the electronic prescription management server 100 (S502).

In addition, the electronic prescription management server 100 may generate or update adverse reaction history information based on the adverse reaction information (S503).

In addition, the electronic prescription management server 100 may generate adverse reaction notification information based on the adverse reaction history information (S504) and transmit the generated adverse reaction notification information to the hospital terminal 20 (S505).

In addition, the doctor may write prescription contents using a chart program for each hospital based on the adverse reaction history information transmitted to the hospital terminal 20 (S506). In this case, when the prescription includes a medicine or a component included in the adverse reaction history information, a warning window may be popped up on the hospital terminal 20 .

And, when the prescription output is selected, the hospital terminal 20 may generate a prescription image based on the prescription content (S507). For example, the hospital terminal 20 may generate a JPG image of a prescription to be output based on the contents of the prescription.

Also, the hospital terminal 20 may generate prescription information based on the generated prescription image (S508). Specifically, the hospital terminal 20 may generate prescription information by extracting text (TEXT) included in the prescription image and location information (X-axis, Y-axis) of the text together. In this case, the hospital terminal 20 may encrypt personal identification information (eg, resident registration number, phone number, address, etc.) included in the prescription information.

In addition, the hospital terminal 20 may transmit the generated prescription information to the electronic prescription management server 100 . In this case, the hospital terminal 20 may transmit the prescription image together with the prescription information to the electronic prescription management server 100 .

When prescription information is received from the hospital terminal 20 or there is a user's request, the electronic prescription management server 100 may transmit an electronic prescription for customer storage to the user terminal 10 (S510). Specifically, the electronic prescription management server 100 may generate an electronic prescription for customer storage based on the terminal information and the prescription information and transmit it to the user terminal 10 . Here, the terminal information may include a type of the user terminal 10 , a version of an application, a prescription form, and the like. Through this, the electronic prescription can be provided in various prescription forms to various terminals.

In addition, when the patient visits the pharmacy or there is a user's request, the electronic prescription management server 100 may transmit the electronic prescription for submission to the pharmacy terminal 30 (S511). Specifically, the electronic prescription management server 100 may transmit prescription information to the pharmacy terminal 30 in XML or JSON format, and may also transmit a prescription image. In this case, the electronic prescription management server 100 may also transmit adverse reaction history information to the pharmacy terminal 30 .

The pharmacist may prepare a drug based on the electronic prescription received by the pharmacy terminal 30 , and then generate a dispensing result (S512) and transmit the dispensing result to the electronic prescription management server 100 (S513).

The electronic prescription management server 100 confirms whether or not an alternative dispensing is based on the dispensing result (S514), and when an alternative dispensing occurs, the electronic prescription management server 100 transmits the replacement dispensing fact to the user terminal (S515) and the hospital It is possible to transmit the fact of the replacement preparation to the terminal 20 (S516).

On the other hand, the electronic prescription management server 100 checks the presence or absence of a component that can cause an adverse reaction in the patient based on the dispensing result, and when the component that induces an adverse reaction is included, transmits the fact that the component is included to the user terminal 10 . can

As described above, according to the present invention described above, it is possible to check a hospital prescription or transmit an electronic prescription to a desired pharmacy through the user terminal, thereby providing high convenience to the user.

In addition, according to the present invention, the patient can easily identify the drug component causing his or her adverse reaction by inputting the prescribed drug and symptoms, and manage the drug component causing the adverse reaction.

In addition, according to the present invention, the patient can use the adverse reaction history information to prevent adverse reactions or side effects (antagonism, effect alteration, etc.) due to interaction with the drug currently being taken.

On the other hand, in the specification and claims, terms such as "first", "second", "third" and "fourth" are used to distinguish between similar elements, if any, and this is not necessarily the case. Used to describe a specific sequence or sequence of occurrences. It will be understood that the terms so used are interchangeable under appropriate circumstances to enable the embodiments of the invention described herein to operate, for example, in sequences other than those shown or described herein. Likewise, where methods are described herein as including a series of steps, the order of those steps presented herein is not necessarily the order in which those steps may be performed, and any described steps may be omitted and/or Any other steps not described may be added to the method. For example, without departing from the scope of the present invention, a first component may be referred to as a second component, and similarly, the second component may also be referred to as a first component.

In addition, the terms used herein are for the purpose of describing the embodiments and are not intended to limit the present invention. As used herein, the singular expression includes the plural expression unless the context clearly dictates otherwise. In the present application, terms such as "consisting of" or "comprising" should not be construed as necessarily including all of the various components or various steps described in the specification, some of which components or some steps are It should be construed that it may not include, or may further include additional components or steps.

So far, the present invention has been looked at with respect to preferred embodiments thereof. All embodiments and conditional examples disclosed throughout this specification have been described with the intention of helping those skilled in the art to understand the principles and concepts of the present invention, those skilled in the art It will be understood that the present invention may be implemented in a modified form without departing from the essential characteristics of the present invention.

Therefore, the disclosed embodiments are to be considered in an illustrative rather than a restrictive sense. The scope of the present invention is indicated in the claims rather than the foregoing description, and all differences within the scope equivalent thereto should be construed as being included in the present invention.

Meanwhile, the method according to various embodiments of the present invention described above may be implemented as a program and provided to a server or devices. Accordingly, each device can download the program by accessing the server or device in which the program is stored.

In addition, the above-described method according to various embodiments of the present invention may be implemented as a program and stored in various non-transitory computer readable media to be provided. The non-transitory readable medium refers to a medium that stores data semi-permanently, rather than a medium that stores data for a short moment, such as a register, cache, memory, etc., and can be read by a device. Specifically, the above-described various applications or programs may be provided by being stored in a non-transitory readable medium such as a CD, DVD, hard disk, Blu-ray disk, USB, memory card, ROM, and the like.

In addition, although preferred embodiments of the present invention have been illustrated and described above, the present invention is not limited to the specific embodiments described above, and the technical field to which the present invention pertains without departing from the gist of the present invention as claimed in the claims Various modifications are possible by those of ordinary skill in the art, and these modifications should not be individually understood from the technical spirit or prospect of the present invention.

Claims (10)

In the prescription management method of the electronic prescription management server,
receiving the patient's adverse reaction information through the user terminal;
generating or updating adverse reaction history information based on the input adverse reaction information;
generating adverse reaction notification information based on the adverse reaction history information and transmitting it to a hospital terminal;
Receiving the prescription information generated based on the abnormal reaction notification information from the hospital terminal;
The step of generating or updating the history information includes:
Using the ingredient code of the drug prescribed in the prescription, it is determined whether there is a single or multiple ingredient,
When the drug is a complex ingredient, common related ingredients in the prescription history in which the adverse reaction is registered among the related ingredients constituting the complex ingredient are extracted, and the drug that is expected to have an adverse reaction including the extracted common related ingredient is an adverse reaction drug By further classifying into sets, the adverse reaction history information is generated,
The adverse reaction history information is
In consideration of the expected half-life of previously prescribed drugs, it is updated by excluding from the set of adverse reaction drugs, drugs containing related ingredients in the unregistered prescription history of adverse reactions that have passed the onset of drug effects based on the time of prescription,
The expected half-life is,
By inputting the relevant components constituting the composite component and body information including body weight, age and gender as inputs, the weights calculated by inputting the related components and body information into the neural network trained to calculate the weight of the half-life are applied to the half-life of the drug. Prescription management method, characterized in that calculated. The method of claim 1,
and transmitting the electronic prescription for customer storage to the user terminal when the patient requests the electronic prescription. The method of claim 1,
transmitting an electronic prescription for submission to the pharmacy when the patient requests the pharmacy through the patient terminal; and
Receiving a dispensing result from the pharmacy; prescription management method further comprising a. 4. The method of claim 3,
checking whether the electronic prescription is a substitute for the electronic prescription based on the dispensing result; and
The method of managing a prescription, characterized in that it further comprises; transmitting the information on the replacement medicine to the user terminal and the hospital terminal when the replacement medicine is generated. The method of claim 1,
The generating and transmitting the adverse reaction notification information to the hospital terminal comprises generating the adverse reaction notification information based on the disclosure range set by the patient. The method of claim 1,
The step of generating or updating the adverse reaction history information
determining a drug component causing an adverse reaction by analyzing the drug ingredient code based on the adverse reaction information; and
Further comprising; generating or updating adverse reaction history information based on the determined pharmaceutical ingredient;
The adverse reaction information includes at least one of the name of the drug administered, the name of the ingredient, and the prescription, and each adverse reaction symptom is matched. delete The method of claim 1,
Predicting a component likely to have an adverse reaction in the patient based on the adverse reaction history information; Prescription management method further comprising a. A prescription management method of an electronic prescription system including a hospital terminal, a patient terminal, a pharmacy terminal, and an electronic prescription management server, the method comprising:
receiving, by the patient terminal, the patient's adverse reaction information from the patient, and transmitting the inputted adverse reaction information to the prescription management server;
generating or updating, by the prescription management server, adverse reaction history information based on the input adverse reaction information;
generating, by the prescription management server, abnormal reaction notification information based on the adverse reaction history information, and transmitting it to the hospital terminal;
generating, by the hospital terminal, the patient's prescription information based on the transmitted adverse reaction notification information, and transmitting the generated prescription information to the electronic prescription management server;
The step of generating or updating the adverse reaction history information includes:
Using the ingredient code of the drug prescribed in the prescription, it is determined whether there is a single or multiple ingredient,
When the drug is a complex ingredient, common related ingredients in the prescription history in which the adverse reaction is registered among the related ingredients constituting the complex ingredient are extracted, and the drug that is expected to have an adverse reaction including the extracted common related ingredient is an adverse reaction drug By further classifying into sets, the adverse reaction history information is generated,
The adverse reaction history information is
In consideration of the expected half-life of previously prescribed drugs, it is updated by excluding from the set of adverse reaction drugs, drugs containing related ingredients in the unregistered prescription history of adverse reactions that have passed the onset of drug effects based on the time of prescription,
The expected half-life is,
By inputting the relevant components constituting the composite component and body information including body weight, age and gender as inputs, the weights calculated by inputting the related components and body information into the neural network trained to calculate the weight of the half-life are applied to the half-life of the drug. A prescription management method of an electronic prescription system, characterized in that calculated. A program recorded on a computer-readable recording medium in which a program code for executing the prescription management method according to any one of claims 1 to 6 and 8 is recorded.

Images