KR102274177B1 - Viscometer Using Method of Viscometer and Program for Measuring Viscometer - Google Patents

Abstract

A viscometer and a method of using the same are provided. The viscometer includes a reference solution channel providing a flow path in a plane direction with respect to a reference solution, a test solution channel providing a flow path in a plane direction with respect to the test solution, and between the thickness direction of the reference solution channel and the thickness direction of the test solution channel. and a mixing channel in which the reference solution and the test solution are mixed, wherein the reference solution moves in a thickness direction of the reference solution channel, and the test solution moves in a thickness direction of the test solution channel, A viscosity value of the test solution is obtained based on the colors of the reference solution and the test solution mixed in the mixing channel and mixed in the mixing channel.

Description

Viscometer Using Method of Viscometer and Program for Measuring Viscometer

The present invention relates to a viscometer, a method of using a viscometer, and a viscometer program, and more particularly, a viscometer, using a viscometer, in which the viscosity value of the test solution is obtained based on the color of the incorporated reference solution and the test solution methods and viscometry programs.

There is an increasing need for solution properties, among other things, for solution viscosity measurement technology.

The measurement of plasma viscosity (PV) in solution is one of the blood tests to examine the abnormal increase in blood flow protein due to inflammation or infection. It is used to monitor the activity of hyperviscosity syndrome or rheumatoid arthritis without being affected by the hematocrit. useful.

Unlike the erythrocyte sedimentation rate (ESR), which is currently widely used for blood tests, the viscometer is not widely used due to difficulties in use. Specifically, since the general viscometer measures the resistance of the fluid located between the rotating bodies or the viscosity through the time it takes to flow through the capillary, there is a problem that precise measuring equipment and a relatively long time are required.

Therefore, research on a new platform viscometer that is inexpensive, easy to use, and does not require additional external equipment is required. Accordingly, the present inventors have invented a viscometer, a method of using a viscometer, and a viscosity measurement program that can measure viscosity more simply and quickly.

One technical problem to be solved by the present invention is to provide a viscometer capable of quickly measuring viscosity, a method of using a viscometer, and a viscosity measurement program.

Another technical problem to be solved by the present invention is to provide a portable viscometer, a method for using a viscometer and a viscosity measurement program.

Another technical problem to be solved by the present invention is to provide a high-accuracy viscometer, a method for using a viscometer, and a viscosity measurement program.

Another technical problem to be solved by the present invention is to provide a viscometer, a method of using a viscometer, and a viscosity measurement program with excellent economical efficiency.

The technical problem to be solved by the present invention is not limited to the above.

In order to solve the above technical problem, the present invention provides a viscometer.

According to an embodiment, the viscometer includes a reference solution channel providing a flow path in a plane direction with respect to a reference solution, a test solution channel providing a flow path in a plane direction with respect to the test solution, and a thickness direction of the reference solution channel and the test solution and a mixing channel located between the channels in the thickness direction, in which the reference solution and the test solution are mixed, wherein the reference solution moves in the thickness direction of the reference solution channel, and the test solution flows in the test solution channel. Moving in the thickness direction, the viscosity value of the test solution is obtained based on the colors of the reference solution and the test solution mixed in the mixing channel and mixed in the mixing channel.

According to an embodiment, the reference solution channel and the mixing channel directly contact and overlap the reference solution channel and the mixing channel in a thickness direction, and the test solution channel and the mixing channel are the test solution channel and the mixing channel. can be overlapped by direct contact in the thickness direction of

According to an embodiment, the reference solution channel, the test solution channel, and the mixing channel may be formed of a porous material.

According to an embodiment, the reference solution channel, the test solution channel, and the mixing channel may be provided as chromatography paper.

According to an embodiment, the reference solution may move the reference solution channel and the mixing channel by capillary force, and the test solution may move the test solution channel and the mixing channel by capillary force.

According to an embodiment, the mixing channel blocks mixing in which at least one of movement of the reference solution from the reference solution channel to the mixing channel and movement of the test solution from the test solution channel to the mixing channel is blocked. and a region and an entrainment occurrence region in which movement of the reference solution from the reference solution channel to the mixing channel and movement of the test solution from the test solution channel to the mixing channel are permitted.

According to an embodiment, in the mixing generation region, the planar direction flow path provided by the reference solution channel and the planar direction flow path provided by the test solution channel may be in the same direction.

According to an embodiment, the mixing occurrence region of the mixing channel may be exposed to the outside so that colors of the mixed reference solution and the test solution are photographed.

According to an embodiment, the viscometer may further include a measuring unit for obtaining a viscosity value of the test solution based on the colors of the reference solution and the test solution mixed in the mixing channel and the viscosity of the reference solution. .

According to an embodiment, the color and viscosity of the reference solution provided to the reference solution channel and the color of the test solution provided to the test solution channel may be previously acquired information.

According to an embodiment, an edge region of the reference solution channel, the test solution channel, and the mixing channel may be treated with a non-hydrophilic material.

In order to solve the above technical problem, the present invention provides a method of using a viscometer.

According to an embodiment, the method of using a viscometer includes an inflow step in which a reference solution is introduced through a reference solution channel, a test solution is introduced through a test solution channel, the reference solution moves from the reference solution channel to a mixing channel, A mixing step in which the test solution is mixed by moving from the test solution channel to the mixing channel, and a measuring step of measuring the viscosity of the reference solution based on the colors of the reference solution and the test solution mixed in the mixing channel do.

According to an embodiment, in the introduction step, mixing of the reference solution and the test solution is blocked, and in the mixing step, the reference solution moves from the reference solution channel in the thickness direction of the reference solution channel, and the The method may further include the step of moving and mixing the test solution from the test solution channel in a thickness direction of the test solution channel.

According to an embodiment, the measuring step includes obtaining the colors of the reference solution and the test solution mixed in the mixing channel, and obtaining a viscosity value of the test solution based on the obtained color. may include more.

According to an embodiment, in the measuring step, the viscosity value of the test solution may be obtained by estimating a flow rate ratio of the reference solution and the test solution based on the obtained color.

In order to solve the above technical problem, the present invention provides a viscosity measurement program.

According to one embodiment, the viscosity measurement program is stored in the medium to execute the steps of obtaining the mixing color of the test solution and the reference solution and, based on the obtained mixing color, obtaining the viscosity value of the test solution. do.

The viscometer according to an embodiment of the present invention provides a channel through which the reference solution and the test solution move with a porous material, so that the viscosity value of the test solution based on the colors of the reference solution and the test solution can be easily obtained. have.

In addition, the viscometer according to an embodiment of the present invention, including the reference solution channel, the test solution channel, the mixing channel and the measuring unit, the configuration of the device is simple, the measurement is fast, and the convenience of use can be improved.

In addition, since the viscometer according to an embodiment of the present invention provides a capillary force to the reference solution and the test solution to provide a driving force, it facilitates mixing of the reference solution and the test solution, thereby improving the reliability of viscosity measurement. can

In addition, in the viscometer according to an embodiment of the present invention, the reference solution channel and the test solution channel provide the same external environment for the reference solution and the test solution, so that the accuracy of measuring the viscosity of the test solution can be improved.

1 is a perspective view of a viscometer according to an embodiment of the present invention.
2 is a flowchart for explaining a method of using a viscometer according to an embodiment of the present invention.
3 is a plan view for explaining the inflow step (S110) of FIG.
4 is a cross-sectional view for explaining the inflow step (S110) of FIG.
5 is a plan view for explaining the mixing step (S120) of FIG.
6 is a cross-sectional view for explaining the mixing step (S120) of FIG.
7 is a plan view for explaining the measuring step ( S130 ) of FIG. 2 .
FIG. 8 is a cross-sectional view for explaining the measuring step S130 of FIG. 2 .
9 is an example of using a viscometer according to an embodiment of the present invention.
10 is a graph comparing the theoretical values of the mixing colors of the existing solution and the test solution with the measured values according to the embodiment.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. However, the technical spirit of the present invention is not limited to the embodiments described herein and may be embodied in other forms. Rather, the embodiments introduced herein are provided so that the disclosed content may be thorough and complete, and the spirit of the present invention may be sufficiently conveyed to those skilled in the art.

In this specification, when a component is referred to as being on another component, it may be directly formed on the other component or a third component may be interposed therebetween. In addition, in the drawings, the shape and its thickness are exaggerated for effective description of technical content.

In addition, in various embodiments of the present specification, terms such as first, second, third, etc. are used to describe various components, but these components should not be limited by these terms. These terms are only used to distinguish one component from another. Accordingly, what is referred to as a first component in one embodiment may be referred to as a second component in another embodiment. Each embodiment described and illustrated herein also includes a complementary embodiment thereof. In addition, in the present specification, 'and/or' is used to mean including at least one of the elements listed before and after.

In the specification, the singular expression includes the plural expression unless the context clearly dictates otherwise. In addition, terms such as "comprise" or "have" are intended to designate that a feature, number, step, element, or a combination thereof described in the specification is present, and one or more other features, numbers, steps, configuration It should not be construed as excluding the possibility of the presence or addition of elements or combinations thereof.

In addition, in the following description of the present invention, if it is determined that a detailed description of a related known function or configuration may unnecessarily obscure the gist of the present invention, the detailed description thereof will be omitted.

1 is a perspective view of a viscometer according to an embodiment of the present invention.

Referring to FIG. 1 , the viscometer may include a reference solution channel 100 , a test solution channel 200 , and an mixing channel 300 . In this case, with the mixing channel 300 interposed therebetween, the reference solution channel 100 and the test solution channel 200 may have a stacked structure. Hereinafter, for convenience of explanation, the reference solution channel 100 is provided in direct contact with the upper side of the mixing channel 300 in a planar direction, and the test solution channel 200 is directly located on the lower side of the mixing channel 300 . Let's assume the structure prepared in contact. Hereinafter, each configuration will be described.

Reference solution channel (100)

The reference solution channel 100 may provide a flow path for the reference solution.

According to an embodiment, the reference solution may be selected from solutions having a predetermined viscosity and a predetermined color. In this case, the color of the reference solution may be selected as a solution having a color complementary to the test solution so that a color difference from the test solution, which will be described later, is large. The predetermined viscosity and predetermined color of the reference solution may be information known in advance.

Referring to FIG. 1 , the reference solution channel 100 may provide a flow path in a plane direction of the reference solution channel 100 as shown _{by an arrow F ref .} According to an embodiment, the reference solution channel 100 may provide a flow path starting from an area in which the reference solution is loaded and up to the upper surface of the mixing generating area 310 of the mixing channel 300 to be described later. have. Although FIG. 1 illustrates a structure in which the reference solution channel 100 is bent in a 'L' shape, the shape of the reference solution channel 100 is not limited thereto.

According to an embodiment, the reference solution may move through the reference solution channel 100 by capillary force. In order for the reference solution channel 100 to provide capillary force to the reference solution, the reference solution channel 100 may be made of a porous material. For example, the reference solution channel 100 may be composed of chromatography paper. Accordingly, the reference solution may move along the reference solution channel 100 in the direction of _{F ref shown in FIG. 1 .}

In addition, a predetermined process may be performed to limit the movement of the reference solution to the edge of the reference solution channel 100 , for example, to the edge in the width direction. For example, the width direction edge of the reference solution channel 100 may be treated with a non-hydrophilic material. For example, the non-hydrophilic material may be a wax. Accordingly, the reference solution channel 100 may provide a path for the reference solution to move to the upper surface of the mixing generation region 310 along the flow path provided by the reference solution channel 100 .

test solution channel (200)

The test solution channel 100 may provide a flow path for the test solution.

According to an embodiment, the test solution may be a substance to be analyzed for viscosity, for example, plasma. The test solution has a predetermined color, which may be information known in advance.

The test solution channel 200 may provide a flow path in a plane direction of the test solution channel 200 as shown _{by the arrow F test .} According to an embodiment, the test solution channel 200 may provide a flow path starting from a region in which the test solution is loaded and up to the upper surface of the mixing generating region 310 . In another view, the test solution channel 200 may have a shape symmetrical left and right with respect to the reference solution channel 100 . In FIG. 1 , the test solution channel 200 is also bent in a 'L' shape, but the shape of the test solution channel 200 is not limited thereto.

According to an embodiment, the test solution may move through the test solution channel 200 by capillary force. In order for the test solution channel 200 to provide capillary force to the test solution, the test solution channel 200 may be made of a porous material. For example, the test solution channel 200 may be made of chromatography paper. Accordingly, the test solution may move along the test solution channel 200 in the direction of _{F test shown in FIG. 1 .}

In addition, a predetermined process may be performed to limit the movement of the test solution to an edge of the test solution channel 200 , for example, an edge in a width direction. For example, the width direction edge of the test solution channel 200 may be treated with a non-hydrophilic material. For example, the non-hydrophilic material may be a wax. Accordingly, the test solution channel 200 may provide a path for the test solution to move to the lower surface of the mixing generation region 310 along the flow path provided by the test solution channel 200 .

The test solution channel 200 and the aforementioned reference solution channel 100 may provide a path with the same cross-sectional shape, size, and length for the solution. In other words, since the test solution flowing through the test solution channel 200 and the reference solution flowing through the reference solution channel 100 receive the same mechanical path, a viscosity-dependent flow can be achieved.

In addition, the flow paths provided by the reference solution channel 100 and the test solution channel 200 are located in the same space, so that the reference solution and the test solution channel 200 moving the reference solution channel 100 are separated. The moving test solution may be provided with the same temperature and capillary force.

mixing channel (300)

The mixing channel 300 may provide a flow path so that the reference solution flowing along the reference solution channel 100 and the test solution flowing along the test solution channel 200 are mixed with each other. In particular, the mixing channel 300 may provide a flow path for mixing the reference solution and the test solution in the thickness direction of the reference solution channel 100 and the thickness direction of the test solution channel 200 .

To this end, the mixing channel 300 is located between the thickness direction of the reference solution channel 100 and the thickness direction of the test solution channel 200 , and the mixing generating region 310 and the mixing blocking region 320 . ) and at least one of the measurement area 330 may be included. Hereinafter, each area will be described in detail.

The mixing blocking region 320 is located between the reference solution channel 100 and the test solution channel 200 , and mixing of the fluid flowing through the reference solution channel 100 and the test solution channel 200 . can block That is, in the mixing blocking region 320 , mixing of the reference solution in the reference solution channel 100 and the test solution in the test solution channel 200 may be blocked. Accordingly, the reference solution of the reference solution channel 100 in contact with the mixing blocking region 320 in a planar direction may flow in a planar direction of the reference solution channel 100 . Similarly, the test solution in the test solution channel 200 in contact with the mixing blocking region 320 in the plane direction may flow in the plane direction of the test solution channel 200 .

To this end, the mixing blocking region 320 may be treated with a non-hydrophilic material. For example, the non-hydrophilic material may be a wax.

The mixing generation region 310 may mean a region in which the reference solution and the test solution can be mixed with each other. In the mixing generating region 310, the reference solution flowing above the mixing generating region 310 and the test solution flowing below the mixing generating region 310 are caused by capillary force in the mixing generating region 310 can be introduced into In other words, the reference solution moves in the thickness direction of the reference solution channel 100 , and the test solution moves in the thickness direction of the test solution channel 200 , so that the reference solution in the mixing generation region 310 . and mixing of the test solution may occur.

The measurement area 330 may mean an area capable of measuring the colors of the reference solution and the test solution mixed in the mixing generation area 310 . In other words, the reference solution and the test solution may be mixed in the mixing generation region 310 , and the mixed solution may flow into the measurement region 330 . In this case, since at least a portion of the measurement area 330 is visually exposed to the outside, it is possible to measure the mixed color of the reference solution and the test solution.

Accordingly, the mixing blocking region 320 of the mixing channel 300 provides a planar flow path for the reference solution and the test solution, and the mixing generating region 310 is a mixing flow path between the reference solution and the test solution. can provide Subsequently, the measurement region 330 may provide a path to measure the colors of the mixed reference solution and the test solution. According to an embodiment, the mixing channel 300 may also be made of a porous material, for example, chromatography paper. In this case, the mixing blocking region 320 may be treated to be non-hydrophilic.

According to an embodiment, the viscometer may further include a measuring unit (not shown). The measuring unit may be configured as, for example, a camera to obtain color information of the mixed reference solution and the test solution.

The measurement unit may acquire a viscosity value of the test solution based on color information acquired through a camera. Hereinafter, a method for obtaining the viscosity of the test solution based on the mixing color will be described.

Equation 2 below for obtaining the viscosity value of the test solution may be derived through Darcy's law expressed by Equation 1 below.

[Equation 1]

(Q is the flow rate of the fluid flowing between two points, k is the permeability, A is the cross-sectional area, P is the pressure drop, L is the distance, μ is the viscosity)

As described above, the reference solution channel 100 and the test solution channel 200 are provided with the same size and material, and have the same transmittance (k), cross-sectional area (A), pressure drop (P) and distance (L). have a value Specifically, the distance the reference solution flows from the reference solution channel 100 and moves to the mixing generation region 310 and the test solution flows into the mixing generation region 310 from the test solution channel 200 . The distance traveled is the same. Since the transmittance (k), the cross-sectional area (A), the pressure drop (P), and the distance (L) provided by the reference solution channel 100 and the test solution channel 200 are the same, Equation 1 is It can be summarized by Equation (2).

[Equation 2]

(Q _ref is the flow rate of the reference solution flowing between two points, Q _test is the flow rate of the test solution flowing between the two points, μ _ref is the viscosity of the reference solution, μ _test is the viscosity of the test solution)

In addition, when the reference solution represents a first color (C _ref ) and the test solution represents a second color (C _test ), the flow rate of the reference solution (Q _ref ) and the flow rate of the test solution (Q _test ) Accordingly, the mixed solution of the reference solution and the test solution has a color in which the first and second colors (C _ref , C _test ) are mixed. In this case, the first color (C _ref ) of the reference solution and the second color (C _test ) of the test solution, the flow rate (Q _ref ) of the reference solution, and the flow rate (Q _test ) of the test solution are It has the same relationship as in Equation 3.

[Equation 3]

(C _ref is the color of the reference solution, C _test is the color of the test solution, Q _ref is the flow rate of the reference solution flowing between two points, Q _test is the flow rate of the test solution flowing between the two points, μ _ref is the viscosity of the reference solution , μ _test is the viscosity of the test solution)

That is, in the mixing color of the reference solution and the test solution, as the flow rate of the reference solution increases, the effect of the color of the reference solution increases, and conversely, it can be considered that the color of the test solution increases as the flow rate of the test solution increases. there will be

Therefore, the flow rate (Q _ref , Q _test ) ratio of the reference solution and the test solution can be obtained by the mixing color of the reference solution and the test solution, so that the viscosity value of the test solution can be obtained.

More specifically, the flow rate (Q _ref , Q _{test ) ratio of the reference solution of the first color (C ref ) and the test} solution of the second color (C test ) is measured in the measurement region 330 for the mixing It can be estimated by the color of the solution. For this, an HSV color space may be utilized. Furthermore, it is possible to obtain the viscosity value of the test solution by utilizing a database that correlates the test solution viscosity value according to the mixing color.

The above-described viscometer according to an embodiment of the present invention includes a reference solution channel 100 providing a flow path in a plane direction with respect to a reference solution, a test solution channel 200 providing a flow path in a plane direction with respect to the test solution, and It may include a mixing channel 300 positioned between the thickness direction of the reference solution channel 100 and the thickness direction of the test solution channel 200 and into which the reference solution and the test solution are mixed.

In addition, the reference solution moves in the thickness direction of the reference solution channel 100 , and the test solution moves in the thickness direction of the test solution channel 200 , and is mixed in the mixing channel 300 , and the mixing A viscosity value of the test solution may be obtained based on the colors of the reference solution and the test solution mixed in the channel 300 .

Also, the reference solution and the test solution may flow in the same direction with the mixing blocking region 320 and the mixing generating region 310 interposed therebetween.

That is, according to a temporary example of the present invention, while the reference solution and the test solution flow in the same direction with different channel layers, they move in the thickness direction in the mixing generation region 310 to cause mixing, Mixing of the solution and the test solution can be done properly. If the reference solution and the test solution flow in opposite directions in the same channel layer and are mixed, a mixing boundary is created and mixing is not performed properly. On the contrary, according to an embodiment of the present invention, the channels of the reference solution and the test solution are separated, and the reference solution and the test solution are mixed in the mixing generation region 310 by capillary force, so the accuracy is high. It can provide mixed colors.

2 is a flowchart for explaining a method of using a viscometer according to an embodiment of the present invention, FIG. 3 is a plan view for explaining the inflow step (S110) of FIG. 2, and FIG. 4 is the inflow step (S110) of FIG. is a cross-sectional view for explaining the , Figure 5 is a plan view for explaining the mixing step (S120) of Figure 2, Figure 6 is a cross-sectional view (S120) for explaining the mixing step of Figure 2, Figure 7 is the measurement of Figure 2 It is a plan view for explaining the step S130, and FIG. 8 is a cross-sectional view for explaining the measuring step S130 of FIG. 2 .

Step S110

2 to 4 , the reference solution 110 may be introduced through the reference solution channel 100 , and the test solution 210 may be introduced through the test solution channel 200 ( S110 ).

The reference solution 110 flowing in through the reference solution channel 100 is a material for which color and viscosity information has been previously acquired, and the test solution 210 flowing in through the test solution channel 200 has a color. It may be a material for which information on the has been previously obtained.

The reference solution 110 may move along a plane direction of the reference solution channel 100 , and the test solution 210 may move along a plane direction of the test solution channel 200 . In other words, the reference solution 110 may move along the reference solution moving direction F _ref , and the test solution 210 may move along the test solution moving direction F _test .

In the introduction step ( S110 ), mixing of the reference solution 110 and the test solution 210 into the mixing channel 300 is blocked. Specifically, in the introduction step ( S110 ), the reference solution 110 and the test solution 210 may not be mixed into the mixing channel 300 by the mixing blocking region 320 of the mixing channel 300 . . The mixing blocking region 320 may be treated with a non-hydrophilic material, so that mixing of the reference solution 110 and the test solution 210 may be blocked.

Step S120

2, 5 and 6 , the reference solution 110 moves from the reference solution channel 100 to the mixing channel 300 , and the test solution 210 moves into the test solution channel 200 . ) can be mixed by moving to the mixing channel 300 (S120).

The reference solution 110 moves in the reference solution movement direction F _ref , and flows into the mixing generation region 310 of the mixing channel 300 from the reference solution channel 100 . In addition, the test solution 210 may move in the test solution movement direction F _test and may flow from the test solution channel 200 into the mixing generation region 310 of the mixing channel 300 .

Specifically, the reference solution 110 moves in the thickness direction of the reference solution channel 100 from the reference solution channel 100 by the capillary force provided by the mixing generation region 310 , and the test solution Reference numeral 210 moves in the thickness direction of the test solution channel 200 from the test solution channel 200 by the capillary force provided by the mixing generating region 310 , and mixing occurs in the mixing generating region 310 . can be

Step S130

2, 7 and 8, the viscosity of the test solution 210 is measured based on the colors of the reference solution 110 and the test solution 210 mixed in the mixing channel 300. can be (S130).

The measuring step (S130) is based on the step of obtaining the colors of the reference solution 110 and the test solution 210 mixed in the mixing channel 300 and the obtained color, the test solution 210 obtaining a viscosity value of

The reference solution 110 and the test solution 210 mixed in the mixing generation region 310 of the mixing channel 300 may move to the measurement region 330 of the mixing channel 300 . That is, the mixed reference solution 110 and the test solution 210 may move to the measurement region 330 by capillary force provided by the mixing channel 300 .

The measurement unit 400 obtains the colors of the reference solution 110 and the test solution 210 mixed in the mixing generation region 310 , and based on the obtained colors, Obtain the viscosity value.

The viscosity of the test solution 210 may be obtained through Equation 2 below, as described above. As described above, the flow rate ratio of the reference solution and the test solution is information that can be obtained according to the mixing color of the reference solution and the test solution.

[Equation 2]

(Q _test is the flow rate of the test solution flowing between two points, μ _ref is the viscosity of the reference solution, μ _test is the viscosity of the test solution)

9 is an example of using a viscometer according to an embodiment of the present invention, and FIG. 10 is a measurement result of FIG. 9 .

9 and 10, the viscosity of the test solution is measured using a viscometer according to an embodiment of the present invention. As a reference solution, 900 μM erioglaucine aqueous solution was used to show blue, and as a test solution, 1,870 μM tartrazine aqueous solution was used to show yellow color. The viscosity of the test solution was controlled through the degree of glycerin content.

Referring to Table 1 below, the actual (theoretical) viscosity value of the test solution according to the glycerin content and the YVF (yellow volume fraction) theoretical value calculated from the volume fraction of the yellow test solution with respect to the volume of the blue reference solution will be confirmed. can

Glycerin (wt%) 0 20 30 40 Theoretical viscosity (cP) One 1.75 2.46 3.79 YVF theoretical value 0.5 0.36 0.29 0.21

Referring to Table 1, when the test solution contains 20% glycerin, the viscosity of the test solution becomes higher than the viscosity of the reference solution, so that the volume of the test solution mixed in the mixing area becomes smaller than the volume of the reference solution, Accordingly, it can be confirmed that the YVF decreases. Also, as the content of glycerin included in the test solution increases, the viscosity of the test solution increases, and the volume of the test solution mixed in the mixing generation region gradually decreases compared to the volume of the reference solution. decrease can be seen.

The experimental solution described in Table 1 was applied to a viscometer according to an embodiment of the present invention as shown in FIG. 9 . Figure 9 (A) is a photograph of the viscometer when the test solution contains 20 wt % of glycerin, and Figure 9 (B) is when the test solution contains 30 wt % of glycerin. A photograph was taken, and (C) of FIG. 9 is a photograph of a viscometer when the test solution contains 40 wt% of glycerin.

As the content of glycerin included in the test solution increased, it was confirmed that the color of the mixed solution measured in the mixing channel approached blue close to that of the reference solution. That is, it can be understood that the viscosity of the test solution affects the mixing color.

The color (YVF measurement value) of the mixed solution according to the content of glycerin shown in FIG. 9 and the measured viscosity obtained accordingly are summarized in Table 2 below. That is, the viscometer according to an embodiment of the present invention may provide a viscosity value of the test solution through color analysis of the mixed solution.

Glycerin (wt%) 20 30 40 Measured viscosity (cP) according to an embodiment of the present invention 1.80 2.53 4.18 YVF measurement value according to an embodiment of the present invention 0.3566 0.2829 0.1930

Comparing the actual viscosity values in Table 1 with the viscosity values obtained in Table 2, it can be confirmed that the viscosity values of the viscometer according to the embodiment of the present invention are very consistent with the actual values.

In FIG. 10, the theoretical value of YVF and the measured value (Example) according to the glycerin content of the test solution are shown as a graph. Referring to FIG. 10 , it can be confirmed that there is almost no error between the theoretical value of the mixed color and the measured value of the mixed color according to an embodiment of the present invention.

This is because the reference solution channel providing the flow path of the reference solution and the test solution channel providing the flow path of the test solution provide the same external environment, that is, the same kinematic flow path, temperature, and capillary force for the reference solution and the test solution. interpreted as Accordingly, it can be confirmed that the viscometer according to an embodiment of the present invention is simple and can provide high accuracy.

According to the above-described embodiment of the present invention, since the flow rate difference according to the viscosity in the channel can be recognized by mixing color measurement, the viscosity value of the test solution can be obtained by colorimetric analysis. When measuring the viscosity of a solution using a viscometer according to an embodiment of the present invention, the measurement process is very simple and the measurement time can be shortened. In addition, in the process of measuring the viscosity using a viscometer, the viscosity of the solution can be obtained by measuring only the measurement area without observing the flow of the solution, so that the convenience of use can be improved.

Furthermore, an embodiment of the present invention may be implemented by a computer program. For example, the viscosity measurement program stored in the medium according to an embodiment of the present invention obtains the mixing color of the test solution and the reference solution, and based on the obtained mixing color, the viscosity value of the test solution is obtained It can be done including the step of

As mentioned above, although the present invention has been described in detail using preferred embodiments, the scope of the present invention is not limited to specific embodiments and should be construed according to the appended claims. In addition, those skilled in the art should understand that many modifications and variations are possible without departing from the scope of the present invention.

100: reference solution channel
110: reference solution
200: test solution channel
210: test solution
300: mixing channel
310: mixing occurrence area
320: mixing blocking area
330: measurement area
400: measurement unit
F _ref : direction of movement of reference solution
F _test : Test solution movement direction

Claims (16)

a reference solution channel providing a flow path in a planar direction with respect to the reference solution;
a test solution channel providing a flow path in a plane direction with respect to the test solution; and
and a mixing channel located between the thickness direction of the reference solution channel and the thickness direction of the test solution channel, wherein the reference solution and the test solution are mixed;
The reference solution moves in the thickness direction of the reference solution channel, and the test solution moves in the thickness direction of the test solution channel to be mixed in the mixing channel,
The reference solution and the test solution are mixed by moving in the thickness direction while flowing in the same direction with different channel layers,
A viscometer in which a viscosity value of the test solution is obtained based on the colors of the reference solution and the test solution mixed in the mixing channel.
According to claim 1,
The reference solution channel and the mixing channel directly contact and overlap in the thickness direction of the reference solution channel and the mixing channel,
The test solution channel and the mixing channel directly contact and overlap the test solution channel and the mixing channel in the thickness direction.
According to claim 1,
wherein the reference solution channel, the test solution channel, and the incorporation channel are formed of a porous material.
According to claim 1,
wherein the reference solution channel, the test solution channel and the incorporation channel are provided as chromatography paper.
According to claim 1,
The reference solution moves the reference solution channel and the mixing channel by capillary force,
The test solution is a viscometer that moves the test solution channel and the mixing channel by capillary force.
According to claim 1,
The mixing channel is
an incorporation blocking region in which at least one of movement of the reference solution from the reference solution channel to the mixing channel and movement of the test solution from the test solution channel to the mixing channel is blocked;
and an entrainment generation region that permits movement of the reference solution from the reference solution channel to the incorporation channel and the test solution movement from the test solution channel to the incorporation channel.
7. The method of claim 6,
In the mixing generation region, the plane direction flow path provided by the reference solution channel and the plane direction flow path provided by the test solution channel are in the same direction as each other.
According to claim 1,
A viscometer exposed to the outside so that the colors of the mixed reference solution and the test solution are photographed in the mixing occurrence region of the mixing channel.
According to claim 1,
The viscometer further comprising a measuring unit for obtaining a viscosity value of the test solution based on the colors of the reference solution and the test solution mixed in the mixing channel and the viscosity of the reference solution.
10. The method of claim 9,
The color and viscosity of the reference solution provided to the reference solution channel and the color of the test solution provided to the test solution channel are previously acquired information.
According to claim 1,
and wherein an edge region of the reference solution channel, the test solution channel, and the incorporation channel is treated with a non-hydrophilic material.
an inflow step of introducing a reference solution through a reference solution channel and introducing a test solution through a test solution channel;
a mixing step in which the reference solution moves from the reference solution channel to the mixing channel, and the test solution moves from the test solution channel to the mixing channel to be mixed; and
A measuring step of measuring the viscosity of the reference solution based on the colors of the reference solution and the test solution mixed in the mixing channel,
In the mixing step,
The reference solution moves from the reference solution channel in the thickness direction of the reference solution channel, and the test solution is mixed by moving from the test solution channel in the thickness direction of the test solution channel,
The method of using a viscometer, wherein the reference solution and the test solution are mixed by moving in the thickness direction while flowing in the same direction with different channel layers.
13. The method of claim 12,
In the introduction step, the mixing of the reference solution and the test solution is blocked, the method of using a viscometer.
13. The method of claim 12,
The measuring step is
obtaining the colors of the reference solution and the test solution mixed in the mixing channel; and
Based on the obtained color, the method of using a viscometer further comprising the step of obtaining a viscosity value of the test solution.
15. The method of claim 14,
The measuring step, based on the obtained color, by estimating the flow rate ratio of the reference solution and the test solution, to obtain a viscosity value of the test solution, a method of using a viscometer.
obtaining an incorporation color of the test solution and the reference solution; and
On the basis of the obtained mixing color, stored in the medium to execute the step of obtaining the viscosity value of the test solution,
The reference solution and the test solution are mixed by moving in the thickness direction while flowing in the same direction with different channel layers.

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