KR102233930B1 - Cosmetic composition comprising stabilized ascorbic acid - Google Patents

Abstract

The present invention relates to a cosmetic composition comprising ascorbic acid stably dispersed in a gel structure. More specifically, the present invention relates to a cosmetic composition which uniformly and stably confining ascorbic acid in a gel structure formed by containing a hydrocarbon-based block copolymer, and at least one oil selected from a group consisting of hydrocarbon oil, ester oil, and vegetable oil, thereby being able to store a high content of ascorbic acid for a long time.

Description

Cosmetic composition containing stabilized ascorbic acid {COSMETIC COMPOSITION COMPRISING STABILIZED ASCORBIC ACID}

The present invention relates to a cosmetic composition comprising ascorbic acid stably dispersed in a gel structure. Specifically, a high content of ascorbic acid by uniformly and stably confining ascorbic acid in a gel structure formed of a hydrocarbon-based block copolymer and at least one oil selected from the group consisting of hydrocarbon oil, ester oil and vegetable oil. It relates to a cosmetic composition that can be stored for a long time.

Pure Vitamin C, or Ascorbic Acid, is a component that plays an important role in preventing skin aging by exerting skin whitening, antioxidant effects, and collagen production promotion. Ascorbic acid has a sugar-like structure that is easily oxidized in the form of dihydro-L-ascorbic acid by receiving two electrons. It prevents the oxidization of bio-components.

However, ascorbic acid is easily oxidized by air, moisture, light, heat, metal ions, and bases. acid), L-theronic acid, L-lyxonic acid, etc. This oxidation not only lowers the potency of the product over time, but also lowers the efficacy, and discoloration and deodorization occur, which greatly affects the safety and stability of the product.

Accordingly, there is a need to develop a cosmetic product that safely applies ascorbic acid, which has excellent skin whitening effect, antioxidant effect, and collagen production promotion effect, in a high content.

In this regard, Korean Patent Registration No. 10-0685647 discloses a cosmetic composition stabilizing vitamin C including bergenin. In addition, Korean Patent Registration No. 10-1862229 discloses a cosmetic composition stabilizing vitamin C, including bergenin and fullerine.

An object of the present invention is to provide a cosmetic composition capable of stably storing a high content of ascorbic acid for a long period of time.

The above object is to provide a cosmetic composition comprising a hydrocarbon-based block copolymer, a gel containing at least one oil selected from the group consisting of hydrocarbon-based oils, ester-based oils, and vegetable oils, and ascorbic acid dispersed in the gel. Is achieved by

Preferably, the cosmetic composition is 0.1 to 30% by weight of a hydrocarbon-based block copolymer, 5.0 to 70% by weight of oil, 0.5 to 10% by weight of sunscreen, 0.01 to 1.0% by weight of antioxidant based on the total weight of the cosmetic composition. And 0.1 to 50.0% by weight of ascorbic acid.

Also preferably, the hydrocarbon-based block copolymer may be a hydrogenated styrene/isoprene copolymer.

Also preferably, the hydrocarbon-based oil is isohexadecane (ISOHEXADECANE), the ester-based oil is cetylethylhexanoate (CETYL ETHYLHEXANOATE), and the vegetable oil may be jojoba oil.

In the cosmetic composition according to the present invention, ascorbic acid is stably dispersed in a gel structure comprising a hydrocarbon-based block copolymer and at least one oil selected from the group consisting of hydrocarbon oil, ester oil, and vegetable oil. Ascorbic acid can be preserved for a long time.

All technical terms used in the present invention, unless otherwise defined, have the following definitions and correspond to the meaning as commonly understood by those of ordinary skill in the relevant fields of the present invention. In addition, although preferred methods or samples are described in the present specification, those similar or equivalent are included in the scope of the present invention.

The term “about” refers to 30, 25, 20, 15, 10, 9, 8, 7, 6, 5, or 30, 25, 20, 15, 10, 9, 8, 7, 6, 5, or relative to a reference amount, level, value, number, frequency, percentage, dimension, size, amount, weight or length. It means an amount, level, value, number, frequency, percentage, dimension, size, amount, weight or length varying by 4, 3, 2 or 1%.

Throughout this specification, unless otherwise required by the context, the terms "comprise" and "comprising" include the steps or components presented, or groups of steps or components, but any other step or component, or It is to be understood that it implies that a step or group of components is not excluded.

The present invention provides a high content of ascorbic acid by uniformly and stably confining ascorbic acid in a gel structure formed of a hydrocarbon-based block copolymer and at least one oil selected from the group consisting of hydrocarbon oil, ester oil, and vegetable oil. It relates to a cosmetic composition that can be stored for a long time.

Preferably, it is a cosmetic composition in which ascorbic acid is stably dispersed in a gel structure composed of a hydrocarbon-based block copolymer hydrogenated styrene/isoprene copolymer and a hydrocarbon oil.

The hydrocarbon-based block copolymer used in the present invention preferably contains a block copolymer that is soluble or dispersible in a liquid hydrocarbon-based phase. The polymeric gelling agent can thicken or gel the hydrocarbon-based phase of the composition. The hydrocarbon-based block copolymer of the present invention may in particular be a diblock, triblock, multiblock, radial or star copolymer, or a mixture thereof.

The hydrocarbon-based block copolymer according to the present invention is an amorphous copolymer formed by polymerization of olefins. The olefin may in particular be an elastomeric ethylenically unsaturated monomer. Examples of olefins which may be mentioned are ethylenic carbide monomers comprising 2 to 5 carbon atoms, especially comprising 1 or 2 ethylenic unsaturations, for example ethylene, propylene, butadiene, isoprene or pentadiene Includes.

Preferably, the hydrocarbon-based block copolymer is an amorphous block copolymer of styrene and olefin. Particularly preferred are block copolymers comprising at least one block of styrene and at least one block comprising units selected from butadiene, ethylene, propylene, butylene and isoprene or mixtures thereof.

In particular, the hydrocarbon-based block copolymer is an optionally hydrogenated copolymer containing a styrene block and an ethylene/C3-C4 alkylene block.

According to one preferred embodiment, the hydrocarbon-based block copolymer is preferably selected from styrene-ethylene/propylene copolymer, styrene-ethylene/butadiene copolymer and styrene-ethylene/butylene copolymer, preferably Hydrogenated, one or more diblock copolymers. Diblock copolymers are sold specifically by Kraton Polymers under the name Kraton ® G1701. Most preferably, it may be a hydrogenated styrene/isoprene copolymer (HYDROGENATED STYRENE/ISOPRENE COPOLYMER).

In the cosmetic composition of the present invention, the hydrogenated styrene/isoprene copolymer may be included in an amount of 0.1 to 30% by weight based on the total weight of the cosmetic composition. More preferably, it may be included in an amount of 1.0 to 20% by weight. If it is used in an amount of less than 0.1% by weight, it may be difficult to exhibit the gelling ability, which may cause a problem in the stability of the formulation, and if it is used in excess of 20% by weight, there may be difficulties in manufacturing, and the usability of the formulation may also be a problem.

The composition according to the present invention comprises at least one oil selected from the group consisting of hydrocarbon oils, ester oils and vegetable oils.

According to an embodiment of the present invention, the oil may be any one or two or more selected from the group consisting of hydrocarbon oils, ester oils, and vegetable oils commonly used in the art.

The hydrocarbon oils include paraffinic hydrocarbon oils, olefinic hydrocarbon oils, aliphatic, alicyclic or aromatic hydrocarbon oils, and the like, n-octane, n-nonane, n-decane, n-undecane, n-dodecane, n -Tridecane, n-tetradecane, n-pentadecane, n-hexadecane, n-heptadecane, n-octadecane, petrolatum, paraffin, isoparaffin, ceresin, squalane, squalene, polybutene, polydecene or polyisoprene Etc. can be used. Preferably, isohexadecane (ISOHEXADECANE) can be used.

The ester oils are ascorbyl palmitate, ascorbilinolate, ascorbyl stearate, distearyl maleate, benzyl benzoate, benzyl laurate, butylene glycol dicaprylate/dicaprate, butylene glycol diisononanoate. , Butylene glycol laurate, butylene glycol stearate, butyl isostearate, cetearyl isononanoate, cetearylnonanoate, cetylcaprylate, cetylethylhexanoate, cetylisononanoate, Ethylhexyl caprylate/caprate, ethylhexylisononanoate, ethylhexylisostearate, ethylhexyllaurate, hexyllaurate, octyldodecylisostearate, isopropylisostearate, isostearyl Isononanoate, isostearyl isostearate, isocetylethylhexanoate, neopentyl glycol dicaprate, neopentyl glycol diethylhexanoate, neopentyl glycol diisononanoate, neopentyl glycol diisostearate , Pentaerythrityl stearate, pentaerythrityl tetraethylhexanoate, triethylhexanoin, and the like, but are not limited thereto. Preferably, the ester-based oil may be cetylethylhexanoate (CETYL ETHYLHEXANOATE).

The vegetable oils are olive oil, almond oil, palm oil, malt oil, castor oil, avocado oil, corn oil, soybean oil, rapeseed oil, camellia oil, cottonseed oil, moonshine colostrum oil, jojoba oil, palm oil, coconut oil, rosehip oil or macadama oil Etc.

According to an embodiment of the present invention, it is preferable to use a hydrocarbon-based oil, and in particular, it is preferable to use shorthydrocarbon chain volatile oils such as isohexadecane and isododecane. desirable. Other oils may be used depending on the type of block copolymer used, but it is not appropriate because it may cause a heavy feeling of use and deteriorate usability, and if it is difficult to manufacture at room temperature during manufacture, it may cause oxidation of vitamin C.

The content of oil is not particularly limited, and the content can be adjusted according to the purpose. The content of the oil may be 5 to 70% by weight based on the total weight of the cosmetic composition, more preferably 30 to 70% by weight. If it is less than 5% by weight, the gelling agent hydrogenated styrene isopropylene copolymer is difficult to dissolve, and if it exceeds 70% by weight, the content of vitamin C and the gelling agent decreases, which may cause problems in efficacy and stability.

The cosmetic composition according to the present invention may further include a UV filter selected from the group consisting of an organic sunscreen, an inorganic filter, and a mixture thereof.

As an organic sunscreen among UV filters, dibenzoylmethane derivatives (including butyl methoxydibenzoylmethane), derivatives of cinnamic acid (ethylhexyl methoxycyanamate) methoxycinnamate), salicylates, para-aminobenzoic acids, β,β-diphenylacrylates, benzophenones, benzylidenecamphore derivatives, Phenylbenzimidazoles, triazines, phenylbenzotriazoles and/or anthranilic derivatives.

Examples of the inorganic filter include filters made of inorganic oxides in the form of pigments or nanopigments, especially titanium dioxide or zinc oxide, and the nano dyes are uncoated or uncoated (uncoated or uncoated). non-coated).

In the present invention, the sunscreen is preferably contained in an amount of 0.1 to 10.0% by weight based on the total weight of the cosmetic composition.

In one embodiment of the present invention, the cosmetic composition further contains an antioxidant. The antioxidant may be a fat-soluble antioxidant used in cosmetics, but may be one or more selected from the group consisting of tocopherol, tocopheryl acetate, pentaerythrityltetra-di-t-butylhydroxyhydrocinnamate, lycopene and retinol. have.

In one embodiment of the present invention, ascorbic acid may be included in an amount of 0.1 to 50% by weight based on the total weight of the cosmetic composition. More preferably, it is 1.0 to 40 weight%. If it is less than 0.1% by weight, it is difficult to exert the efficacy of vitamin C, and if it exceeds 50% by weight, the stability and usability of the formulation may be poor.

According to an embodiment of the present invention, the cosmetic composition of the present invention can be prepared by the following method.

First, 0.1 to 30% by weight of a hydrocarbon-based block copolymer hydrogenated styrene/isoprene copolymer (HYDROGENATED STYRENE/ISOPRENE COPOLYMER) in 5.0 to 70% by weight of oil is wetted at room temperature for 3 hours or more. Subsequently, 0.1-10% by weight of a sunscreen is heated to 60°C, and 0.01-1.0% by weight of an antioxidant is dissolved, and then cooled to room temperature. After the cooled sunscreen and antioxidant were added to the oil, the mixture was stirred at room temperature with an azimixer at 700 rpm for 5 to 10 minutes. Thereafter, 0.1 to 50% by weight of ascorbic acid is added and stirred for 3 to 5 minutes to prepare a cosmetic composition in which ascorbic acid is stabilized.

It is preferable that the gelling process (wetting step) of the hydrocarbon-based block copolymer and oil is performed at less than 40°C. If it proceeds at a temperature of 40°C or higher, oxidation of ascorbic acid weak to heat may be promoted and oil may be volatilized. If the hydrocarbon-based block copolymer is wetted in oil for 3 hours or more and then stirred at a temperature of less than 40°C, gelation is possible without applying temperature, thus reducing the energy used for heating and cooling and the energy and time used for stirring using a machine. Not only can it be reduced, but it also helps the stability of Ascorbic Acid, which is vulnerable to heat and air.

Ingredients included in the cosmetic composition of the present invention may include, as an active ingredient, ingredients commonly used in cosmetic compositions in addition to the above active ingredients, for example, conventional auxiliary agents such as antioxidants, stabilizers, solubilizers, pigments and fragrances, And a carrier.

The cosmetic composition of the present invention may be used alone or in duplicate, or may be used in conjunction with other cosmetic compositions other than the present invention. In addition, the cosmetic composition according to the present invention may be used according to a conventional method of use, and the number of times of use thereof may be varied according to a user's skin condition or taste. For example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, cleansing, oils, powder foundations, emulsion foundations, wax foundations, sun creams, packs, shampoos, scalp packs, treatments, massage creams, and Can be used simultaneously with spray.

The cosmetic composition according to the present invention may be in a liquid, gel or cream formulation, and more preferably has a gel formulation.

Hereinafter, the present invention will be described in more detail through examples and experimental examples. These examples are for illustrative purposes only, and it will be apparent to those of ordinary skill in the art that the scope of the present invention is not limited by these examples according to the gist of the present invention.

Examples 1 to 3: Preparation of ascorbic acid gel composition

A cosmetic composition was prepared with the composition shown in Table 1 below. Specifically, isohexadecane (ISOHEXADECANE), cetylethylhexanoate (CETYL ETHYLHEXANOATE), jojoba oil (SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL) 5.0 to 70% by weight of hydrogenated styrene/isoprene copolymer (HYDROGENATED) STYRENE/ISOPRENE COPOLYMER) 0.1-30% by weight was wetted at room temperature for 3 hours or more. Heat the sunscreen, ETHYLHEXYL METHOXYCINNAMATE, to 60°C, and use the antioxidant, pentaerythrityl tetra-di-t-butylhydroxyhydrocinnamate (PENTAERYTHRITYL TETRA-DI-t-BUTYL HYDROXYHYDROCINNAMATE). After melting, it was cooled to room temperature. After the cooled sunscreen and antioxidant were added to the oil, the mixture was stirred at room temperature with an azimixer at 700 rpm for 5 minutes. Thereafter, a sample was prepared by stirring for 3 minutes while adding 0.1 to 50% by weight of ascorbic acid.

Classification (unit: weight%) Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Example 1 Example 2 Example 3 Isohexadecane 74.9 - - 44.9 - - 64.9 - - Cetylethylhexanoate - 74.9 - - 44.9 - - 64.9 - Jojoba Oil - - 74.9 - - 44.9 - - 64.9 Hydrogenated styrene/isoprene copolymer - - - 30 30 30 10 10 10 Ascor Big Acid 20 20 20 20 20 20 20 20 20 Ethylhexylmethoxycinnamate 5 5 5 5 5 5 5 5 5 Pentaerythrityltetra-di-t-butylhydroxyhydrocinnamate 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Sum 100 100 100 100 100 100 100 100 100

Experimental Example 1 : Evaluation of stability and feeling of use

Long-term storage stability evaluation

In order to confirm the long-term stability of Examples 1 to 3 and Comparative Examples 1 to 6, the evaluation was performed according to the following criteria after 3 months under the temperature conditions shown in Table 2 below. In the case of cycle evaluation, it was observed by cycling at 45℃->RT->-10℃.

<Evaluation Criteria>

Very bad (complete separation): 1, Bad (partial separation):2, Good (no separation): 3

division Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Example 1 Example 2 Example 3 RT One One One 3 3 3 3 3 3 4℃ One One One 3 3 3 3 3 3 45℃ One One One 3 2 2 3 2 2 CT(-10℃~45℃) One One One 3 3 2 3 3 2

Referring to Table 2, Comparative Examples 1 to 3 in which the hydrogenated styrene/isoprene copolymer was not used had phase separation under various temperature conditions, and Examples 2 to 3 all maintained stability until 2 months. However, at 3 months, some phase separation was observed at 45°C and CT. Example 1 was confirmed to be stable for 3 months under all conditions.

Usability evaluation

Comparative Examples 4 to 6 and Examples 1 to 3, which had relatively good stability, were divided into two groups for 20 women aged 20 to 40 years, and the Examples and Comparative Examples were used on both parts of the face, and then according to the following evaluation criteria. The feeling of use, such as spreadability, greasyness, stickiness, and moisturizing feeling, was evaluated, and the results are shown in Table 2.

<Evaluation Criteria>

Very Bad: 1, Bad: 2, Average: 3, Good: 4, Very Good: 5

division Comparative Example 4 Comparative Example 5 Comparative Example 6 Example 1 Example 2 Example 3 Spreadability One One One 5 5 4 Greasy 4 4 2 5 5 2 Sticky One One One 5 3 3 Moisturizing 3 3 3 5 4 4

Referring to Table 3, it can be seen that Examples 1 to 3 are superior to Comparative Examples 4 to 6 in which the gelling agent is used a lot. In particular, it can be seen that the spreadability and stickiness are remarkably improved by using an appropriate amount of hydrogenated styrene isopropylene copolymer. Among Examples 1 to 3, it was found that Example 1 using isohexetecan was the most excellent in expressing all feelings of use.

Claims (4)

Hydrogenated styrene/isoprene copolymer as a hydrocarbon-based block copolymer, isohexadecane as a hydrocarbon-based oil, cetylethylhexanoate as an ester-based oil, and jojoba oil as a vegetable oil. Cosmetic composition comprising a gel containing and ascorbic acid dispersed in the gel. The method of claim 1, wherein the cosmetic composition comprises 0.1 to 30% by weight of hydrogenated styrene/isoprene copolymer based on the total weight of the cosmetic composition; 5.0 to 70% by weight of at least one oil selected from the group consisting of isohexadecane, cetylethylhexanoate oil, and jojoba oil; 0.1 to 10.0% by weight of sunscreen; 0.01 to 1.0% by weight of antioxidant; And 0.1 to 50.0% by weight of ascorbic acid. delete delete