KR102222731B1 - 분석물 검출을 위한 범용 바이오센서 시스템 - Google Patents

분석물 검출을 위한 범용 바이오센서 시스템 Download PDF

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KR102222731B1
KR102222731B1 KR1020197021112A KR20197021112A KR102222731B1 KR 102222731 B1 KR102222731 B1 KR 102222731B1 KR 1020197021112 A KR1020197021112 A KR 1020197021112A KR 20197021112 A KR20197021112 A KR 20197021112A KR 102222731 B1 KR102222731 B1 KR 102222731B1
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KR20190099264A (ko
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토마스 제이. 주팬식
조셉 디. 키틀
링춘 장
스리칸트 베다무어씨
리차드 에스. 브로디
마빈 알. 윌리엄스
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펀다멘탈 솔류션스 코포레이션
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • C—CHEMISTRY; METALLURGY
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

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  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020197021112A 2016-12-22 2017-12-21 분석물 검출을 위한 범용 바이오센서 시스템 Active KR102222731B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662438068P 2016-12-22 2016-12-22
US62/438,068 2016-12-22
US15/642,800 US9850546B2 (en) 2015-03-31 2017-07-06 Biosensor system for the rapid detection of analytes
US15/642,800 2017-07-06
PCT/US2017/067787 WO2018119173A1 (en) 2016-12-22 2017-12-21 Universal biosensor system for analyte detection

Publications (2)

Publication Number Publication Date
KR20190099264A KR20190099264A (ko) 2019-08-26
KR102222731B1 true KR102222731B1 (ko) 2021-03-05

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EP (1) EP3559278B1 (https=)
JP (3) JP2020507060A (https=)
KR (1) KR102222731B1 (https=)
CN (1) CN110300807A (https=)
CA (1) CA3046623C (https=)
IL (1) IL267568B2 (https=)
RU (1) RU2737943C1 (https=)
WO (1) WO2018119173A1 (https=)

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EP4018192A1 (en) * 2019-08-21 2022-06-29 Michigan Technological University High-brightness fluorophores for quantification and phenotyping of extracellular vesicles
CN110806481B (zh) * 2019-11-15 2021-09-21 中国农业科学院油料作物研究所 同步检测二乙酸镳草镰刀菌烯醇、黄曲霉毒素b1、杂色曲霉素的时间分辨荧光试剂盒
CN111826400A (zh) * 2020-07-21 2020-10-27 中科宝承生物医学科技有限公司 一种双特异性抗体nk细胞制备方法及其细胞和应用
WO2024254405A2 (en) * 2023-06-07 2024-12-12 Biomarin Pharmaceutical Inc. High throughput screen for genetic variants associated with short stature

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8216797B2 (en) * 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
US7223550B2 (en) * 2001-02-08 2007-05-29 Temple University-Of The Commonwealth System Of Higher Education Biosensor for defecting chemical agents
US20030064362A1 (en) * 2001-09-28 2003-04-03 Silver Robert B. Biosensor for detection of toxic substances
EP2017618A1 (en) * 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Methods and systems for detecting
US9023640B2 (en) * 2011-12-13 2015-05-05 Fundamental Solutions Corporation Device for rapid detection of infectious agents
WO2014160140A1 (en) * 2013-03-13 2014-10-02 Applied Biomolecular Technologies System for rapidly detecting infectious agents using a hybridoma-based biosensor
KR20170127015A (ko) * 2015-03-13 2017-11-20 유니버시티 오브 매릴랜드, 발티모어 만능항체 매개 바이오센서
ES2893879T3 (es) * 2015-03-31 2022-02-10 Fundamental Solutions Corp Sistema biosensor para la detección rápida de analitos
US9752199B2 (en) 2015-03-31 2017-09-05 Fundamental Solutions Corporation Biosensor system for the rapid detection of analytes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHOQUET, D. et al., J. Biol. Chem., 1994년, Vol. 269, pp.6491-6497
CURTIS, T. et al., Biosens. Bioelectron., 2008년, Vol.23, pp.1024-1031
RIDER, T. H. et al., Science, 2003년, Vol. 301, pp. 213-215.

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Publication number Publication date
EP3559278B1 (en) 2024-08-14
IL267568B2 (en) 2023-04-01
JP2025072435A (ja) 2025-05-09
WO2018119173A1 (en) 2018-06-28
JP2023059269A (ja) 2023-04-26
IL267568B (en) 2022-12-01
CA3046623A1 (en) 2018-06-28
CN110300807A (zh) 2019-10-01
CA3046623C (en) 2022-05-17
EP3559278A1 (en) 2019-10-30
IL267568A (en) 2019-08-29
KR20190099264A (ko) 2019-08-26
JP2020507060A (ja) 2020-03-05
RU2737943C1 (ru) 2020-12-07

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