KR102084856B1 - Detachment length adjustable coil structure for embolization and instrument for embolization including the structure - Google Patents

Abstract

Disclosed are a coil structure for embolization capable of adjusting the separation length and an embolization procedure device comprising the same. The coil structure for embolization capable of adjusting the separation length comprises: a coil having an inner space; a fine wire movably located in the inner space of the coil; a heating member formed on the fine wire and heated to a predetermined temperature when receiving current through the fine wire; and a dissolution member formed in contact with the heating member, and is dissolved when the heating member reaches a predetermined temperature. The present invention can reduce stress required for the procedure.

Description

FIELD OF THE INVENTION An embolization coil structure having an adjustable length of separation and an embolization apparatus including the same, and an embolization apparatus including the same.

The present invention relates to an embolic coil structure and an embolization apparatus including the same, and more particularly, to an embolization coil structure and an embolization apparatus including the same.

Aneurysms are intravascular spaces formed by swelling of blood vessel walls due to damage and loss of the elastic layer forming the inner side of blood vessels and the media. If the aneurysm is left as it is, the pressure generated from the blood flow continues and the thickness of the blood vessel wall can be thinned and damaged, and it can burst at any moment. In particular, when a cerebral aneurysm bursts, cerebral hemorrhage occurs, which causes a fatal risk to humans than other aneurysms of blood vessels.

There are two ways to treat cerebral aneurysm: cerebral aneurysm ligation and coil embolization. Cerebral aneurysm ligation is a traditional method used in neurosurgery. It is a surgical procedure that removes the cranial fragments and ligates a cerebral aneurysm located between the brain tissues with a small clip. Coil embolization, on the other hand, is a surgical technique in which a small tube of metal is inserted through the femoral artery on the leg side to access the cerebral artery, and then a coil is inserted into the cerebral aneurysm. Coil embolization, unlike cerebral aneurysm ligation, does not open a cranial opening procedure. Therefore, the operation of the coil embolus is short and the recovery is possible within a few days after the procedure.

On the other hand, in coil embolization, if the coil is sufficient to fill the cerebral aneurysm, the remaining coil may exit the cerebral aneurysm inlet. In such a case, the coils filled in the cerebral aneurysm can be removed, discarded, and replaced with shorter coils to perform embolization again.

One aspect of the present invention provides an embolization coil structure and embolization apparatus including the same embodied to cut the coil at a desired point of the entire length of the coil filled in the aneurysm.

The embolization coil structure that can adjust the separation length of the present invention for solving the above problems is formed in the coil, the inner wire is formed, the fine wire movably located in the inner space of the coil, the fine wire, the fine wire It is formed in contact with the heating member and the heating member is heated to a predetermined temperature when the current is supplied through a, and includes a melting member that is dissolved when the heating member reaches a predetermined temperature.

Meanwhile, the coil may be formed of a material that dissolves when the heating member reaches a preset temperature.

In addition, the dissolution member may be formed of a radiopaque material.

In addition, the heating member is heated to a predetermined temperature in a state of being located at the attachment point set in the coil by the movement of the fine wire, so that the attachment point is dissolved to reference the attachment point. The coil can be separated by.

In addition, the dissolution member may dissolve at the attachment point to close the coil separated based on the attachment point.

In addition, the melting member may be formed such that the heating member is formed at a position spaced apart from the distal end by a predetermined distance and the heating member is in contact with the heating member toward the distal end with respect to the heating member.

On the other hand, the embolization apparatus of the present invention, the coil is formed in the inner space and the movable position in the inner space of the coil, when the current is supplied to separate a portion of the coil is heated to a predetermined temperature and inserted into the aneurysm A coil structure including a heating member, a fine conduit forming a moving passage of the coil structure, a push wire for pushing the coil structure into an aneurysm through the micro conduit, and a power supply device supplying current to the coil structure. do.

On the other hand, the coil structure, the coil is formed in the inner space, the fine wire which is movably located in the inner space of the coil, is formed in the fine wire, when the current is supplied through the fine wire is heated to a predetermined temperature It may include a heating member and a melting member which is formed in contact with the heating member, and dissolves when the heating member reaches a predetermined temperature.

In addition, the fine wire may be connected to the internal space of the push wire from the internal space of the coil.

In addition, the heating member is heated to a predetermined temperature in a state of being located at the attachment point set in the coil by the movement of the fine wire, so that the attachment point is dissolved to reference the attachment point. The coil can be separated by.

The embolization coil structure according to the present invention is implemented to break the coil at a desired point of the entire length of the coil filled in the aneurysm, thereby reducing the waste of the coil due to re-embolization. In addition, it is possible to shorten the time of embolization procedure and reduce the stress required for the procedure.

1 is a view showing an embolic state of an aneurysm using the embolization apparatus according to the present invention.
2 is a view schematically showing an embolization procedure apparatus according to an embodiment of the present invention.
3 is a view illustrating a part of the embolization coil structure according to an embodiment of the present invention.
4 is an enlarged view of a portion A of FIG. 3.
FIG. 5 is a diagram illustrating an example in which the fine wire illustrated in FIG. 3 is moved.
6 and 7 are enlarged views of part B of FIG. 5.

DETAILED DESCRIPTION OF THE INVENTION The following detailed description of the invention refers to the accompanying drawings that show, by way of illustration, specific embodiments in which the invention may be practiced. These embodiments are described in sufficient detail to enable those skilled in the art to practice the invention. It is to be understood that the various embodiments of the invention are different but need not be mutually exclusive. For example, certain shapes, structures, and characteristics described herein may be embodied in other embodiments without departing from the spirit and scope of the invention in connection with one embodiment. In addition, it is to be understood that the location or arrangement of individual components within each disclosed embodiment may be changed without departing from the spirit and scope of the invention. The following detailed description, therefore, is not to be taken in a limiting sense, and the scope of the present invention is defined only by the appended claims, along with the full scope of equivalents to which such claims are entitled. Like reference numerals in the drawings refer to the same or similar functions throughout the several aspects.

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the drawings.

1 is a view showing an embolic state of an aneurysm using the embolization apparatus according to the present invention.

Referring to FIG. 1, the aneurysm 2 is a space in the blood vessel 1 in which a blood vessel wall swells as the elastic layer and the medial layer of the blood vessel 1 are damaged or missing. If the aneurysm 2 is left as it is, the thickness of the blood vessel wall may be continuously thinned and damaged due to the pressure generated from the continuous blood flow, and may burst at any moment. Coil embolization is one of the methods of treating this aneurysm 2. Coil embolization is a procedure for preventing blood flow into the aneurysm 2 by filling the coil structure 100 in the aneurysm 2.

The embolization apparatus 1000 (see FIG. 2) according to an embodiment of the present invention may include a fine conduit 200 and a coil structure 100. Briefly describing coil embolization using another embolization apparatus 1000 according to an embodiment of the present invention, the micro-conduit 200 may enter the aneurysm 2. At this time, although not shown in Figure 1, the embolization procedure apparatus 1000 according to an embodiment of the present invention further comprises a guide catheter, placing the guide catheter under the aneurysm (2), the fine catheter 200 guide catheter Advance inward to enter the aneurysm 2.

Then, the coil structure 100 may be pushed into the aneurysm 2 through the fine conduit 200 that enters the aneurysm 2. Although not shown in FIG. 1, the embolization procedure apparatus 1000 according to an embodiment of the present invention further includes a push wire extending from the coil structure 100, and uses the push wire to form the aneurysm (coil structure 100). 2) It can be pushed inside.

Finally, the push wire can be separated from the coil structure 100 filled in the aneurysm 2. In this case, according to the related art, in most cases, the boundary point between the coil structure 100 and the push wire is defined as a detachment point. Thus, upon separation of the coil structure 100 and the push wire at the attachment point, a portion of the coil structure 100 may protrude out of the aneurysm 2. In this case, the coil structure 100 filled in the aneurysm 2 is removed and discarded, and embolization is performed again using the shorter coil structure 100.

Embolization apparatus 1000 according to an embodiment of the present invention is configured to enable the adjustment of the attachment point, the coil structure filled in the aneurysm 2 in a manner to generate heat by applying a current to the attachment point You can break (100). Therefore, the waste of the coil structure 100 used for embolization can be reduced, the procedure time can be shortened, and the stress required for the procedure can be reduced. In this regard, it will be described in detail with reference to FIGS. 2 to 7.

First, FIG. 2 is a view schematically showing an embolization procedure apparatus according to an embodiment of the present invention.

Referring to FIG. 2, an embolization apparatus 1000 according to an embodiment of the present invention may include a coil structure 100, a fine conduit 200, a push wire 300, and a power supply device 500. .

The coil structure 100 is configured to be filled in the aneurysm 2 and may be implemented to be separated at a desired point of the entire length. In this regard, a detailed description will be described later with reference to FIGS. 3 to 7.

The fine conduit 200 has a round shape having a constant diameter in cross section, and an inner space 201 through which the coil structure 100 and the push wire 300 described later may pass may be formed. The coil structure 100 and the push wire 300 may be formed to have a diameter sufficiently smaller than the inner diameter of the fine conduit 200 to move the internal space 201 of the fine conduit 200 as a moving passage.

The push wire 300 is a member extending from the embolization coil structure 100, and may pull the coil structure 100 from the fine conduit 200. For example, during embolization, the push wire 300 may push the coil structure 100 into the aneurysm 2 through the micro-conduit 200.

The power supply device 500 may supply a current to the coil structure 100. The coil structure 100 may receive a current from the power supply device 500 and be disconnected at a desired point of the entire length.

In the coil embolization procedure using the embolization procedure apparatus 1000 according to an embodiment of the present invention, the micro-conduit 200 enters the aneurysm 2, and pushes the push wire 300 to the coil in the aneurysm 2. The structure 100 may be filled. When the coil structure 100 is sufficiently filled in the aneurysm 2, the current is supplied from the power supply device 500 to the coil structure 100, and the portion of the coil structure 100 located in the aneurysm 2 and the aneurysm ( 2) The part located outside can be separated.

3 is a view illustrating a portion of the embolization coil structure according to the embodiment of the present invention, and FIG. 4 is an enlarged view of portion A of FIG. 3.

3 and 4, the embolization coil structure 100 according to an embodiment of the present invention may include a coil 110, a fine wire 130, a heating member 150, and a dissolution member 180. Can be.

The coil 110 has a round shape having a constant diameter in cross section, and an inner space 101 through which the fine wire 130 described later may pass may be formed. The coil 110 may fill the inside of the aneurysm 2 while forming a spiral wound shape.

The coil 110 may be formed of a metallic or nonmetallic material that is dissolved at a predetermined temperature. The preset temperature may be a heating temperature of the heating member 150 described later. Therefore, when the heating member 150 is heated to a preset temperature, the coil 110 may be separated by dissolving the corresponding position. In this regard, a detailed description will be made later.

The fine wire 130 may be formed of a wire having a diameter sufficiently smaller than the inner diameter of the coil 110 to be movably positioned in the inner space 101 of the coil 110.

The fine wire 130 may be a current line for current transfer or may include a current line. The fine wire 130 may be inserted into the inner space 101 of the coil 110 through the tip portion, and the opposite side thereof may be connected to the power supply 500. The fine wire 130 may be connected to the power supply device 500 by extending from the internal space 101 of the coil 110 to the internal space of the push wire 300, and may include a tip portion of the current supplied from the power supply device 500. Can be delivered to.

The heating member 150 and the dissolution member 180 may be formed in the fine wire 130.

The heating member 150 may be formed at a position spaced a predetermined distance from the tip of the fine wire 130. The dissolution member 180 may be formed in contact with the front end side of the heating member 150. That is, the melting member 180 may be positioned at the tip end with respect to the heating member 150.

The heating member 150 may be formed of an electrically resistant material, and may be heated to a preset temperature when a current is supplied through the fine wire 130.

The dissolution member 180 may be formed of a metallic or nonmetallic material that is dissolved at a predetermined temperature. For example, the dissolution member 180 may be formed of the same material as the coil 110. The preset temperature may be a heating temperature of the heating member 150. Therefore, when the heating member 150 is heated to a predetermined temperature, the melting member 180 may be dissolved.

In addition, the dissolution member 180 may be formed of a radio-opacity material so that the operator can determine the position of the heating member 150 under X-ray perspective.

In the embolization coil structure 100 according to an embodiment of the present invention, the attachment point of the coil 110 may be adjusted by moving the heating member 150 using the fine wire 130.

FIG. 5 is a view illustrating an example in which the fine wire illustrated in FIG. 3 is moved, and FIGS. 6 and 7 are enlarged views of part B of FIG. 5.

Referring to FIG. 5, the attachment point P may be set in the coil 110. The detachment point P may be defined as a reference point when cutting off a part of the entire length of the coil 110. For example, during embolization, if part of the entire length of the coil 110 protrudes into the lumen of the normal blood vessel 1 outside the aneurysm 2, the inlet of the aneurysm 2, or the aneurysm 2 and the normal vessel A point corresponding to the boundary line of (1) may be set as the attachment point P. FIG.

The fine wire 130 may be moved so that the heating member 150 may be aligned with the attachment point P. FIG. It can be pulled in the direction of the arrow shown in FIG. In this case, the dissolution member 180 may serve to guide the position of the heating member 150. The operator recognizes the position of the heating member 150 using the melting member 180 as a marker under the X-ray perspective, and the fine wire 130 is arranged so that the heating member 150 can be aligned with the detachment point P. FIG. Can push or pull.

Referring to FIG. 6, when the heating member 150 is aligned with the attachment point P, the heating member 150 may receive a current through the fine wire 130. The heating member 150 may receive a current and be heated to reach a preset temperature.

When the heating member 150 reaches a preset temperature, the detachment point P of the coil 110 may be dissolved. The coil 110 may be separated into the proximal portion 110a and the distal portion 110b while being broken based on the attachment point P. For example, during embolization, the proximal portion 110a may be a portion left in the aneurysm 2 and the distal portion 110b may be a portion recovered out of the body. In addition, when the heating member 150 reaches a preset temperature, the melting member 180 may also start to dissolve at the attachment point P.

Referring to FIG. 7, the dissolution member 180 ′ may dissolve at the detachment point P to close the coil 110 separated based on the detachment point P. Referring to FIG. The coil 110 may be broken based on the attachment point P, and the internal space 101 may be opened from the broken cross section. The melting member 180 ′ may be dissolved in the broken cross section of the coil 110. In addition, the melting member 180 may move away from the heating member 150 as the fine wire 130 is pulled in the direction of the arrow shown in FIG. 6. The melting member 180 ′ may close the cross section while solidifying the broken cross section of the coil 110. For example, during the embolization procedure, the dissolution member 180 may close the broken section of the proximal portion 110a, which is a portion left in the aneurysm 2.

As such, the embolization coil structure 100 according to an embodiment of the present invention is implemented to move the heating member 150 in the internal space of the coil 110, thereby desired point of the entire length of the coil 110. The coil 110 can be cut off.

Although described above with reference to the embodiments, those skilled in the art will understand that various modifications and changes can be made within the scope of the invention without departing from the spirit and scope of the invention as set forth in the claims below. Could be.

1: blood vessel
2: aneurysm
100: coil structure for embolization
101, 201: interior space
110: coil
130: fine wire
150: heating member
180: dissolution member
200: fine conduit
300: push wire
500: power supply

Claims (10)

A coil in which an inner space is formed;
A fine wire movably positioned in an inner space of the coil;
A heating member formed on the fine wire and heated to a preset temperature when current is supplied through the fine wire; And
It is formed in contact with the heating member, and comprises a melting member that dissolves when the heating member reaches a predetermined temperature,
The heating member,
The coil is heated to a predetermined temperature in a state where it is located at a detachment point set in the coil by the movement of the fine wire, and the detachment point is dissolved to separate the coil based on the detachment point.
The coil is,
The inner space is separated from the proximal portion left in the aneurysm and the distal portion recovered out of the body based on the attachment point, and the coil is opened from the cross-section separated into the proximal portion and the distal portion.
The melting member,
An embolization coil structure capable of adjusting the separation length, which is dissolved by the heating member in a state in which it is disposed on the same plane as the attachment point and closes the open section of the inner space of the proximal portion. The method of claim 1,
The coil is,
And a coil structure for embolization that can control a separation length formed of a material that is dissolved when the heating member reaches a preset temperature. The method of claim 1,
The dissolution member,
An embolization coil structure capable of adjusting the separation length formed of a radiopaque material. delete delete The method of claim 1,
The fine wire,
The heating member is formed at a position spaced apart from the distal end portion, the embolization coil structure capable of adjusting the separation length is formed so that the melting member is in contact with the heating member toward the distal end around the heating member. A coil structure including a coil having an inner space and a heating member movably positioned in the inner space of the coil, the heating member being separated to a part of the coil inserted into an aneurysm by heating to a predetermined temperature when a current is supplied;
A fine conduit forming a movement passage of the coil structure;
A push wire for pushing the coil structure into the aneurysm through the microconduit; And
A power supply for supplying current to the coil structure,
The coil structure,
A coil in which an inner space is formed;
A fine wire movably positioned in an inner space of the coil;
A heating member formed on the fine wire and heated to a preset temperature when current is supplied through the fine wire; And
It is formed in contact with the heating member, and comprises a melting member that dissolves when the heating member reaches a predetermined temperature,
The heating member,
The coil is heated to a preset temperature in a state where it is located at a detachment point set in the coil by the movement of the fine wire, and the detachment point is dissolved to separate the coil based on the detachment point.
The coil is,
The inner space is separated from the proximal portion left in the aneurysm and the distal portion recovered out of the body based on the attachment point, and the coil is opened from the cross-section separated into the proximal portion and the distal portion.
The melting member,
An embolization treatment apparatus, which is dissolved by the heating member in a state where it is located on the same plane as the attachment point, and closes the open section of the inner space of the proximal portion. delete The method of claim 7, wherein
The fine wire,
And an embolization procedure extending from the inner space of the coil to the inner space of the push wire. The method of claim 7, wherein
The heating member,
Embolization to be heated to a predetermined temperature in the state located on the attachment point set in the coil by the movement of the fine wire, so that the attachment point is dissolved to separate the coil based on the attachment point Procedure.

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