KR102081839B1 - Pain-sensitivity analyzer and method thereof - Google Patents

Abstract

It is an object of the present invention to quantify the pain felt by a patient with objective criteria. To this end, the pain input unit for dividing the stimulus into a multi-step stimulus can be added to the human body; and the EEG measuring unit for measuring the EEG while the stimulus is added to the human body; A quantitative pain sensitivity measurement apparatus is provided, including; and an EEG display unit displaying the EEG change so that the EEG changes depending on the stimulus input step by step in the pain input unit.

Description

Quantified Pain Sensitivity Measurement Apparatus and Method thereof

The present invention relates to an apparatus and method for measuring and analyzing pain by quantifying the pain through a mechanical or electrical device.

The pain the patient feels is so subjective that it is not easy for the doctor to find out. In addition, even if the patient tells how much pain he or she is experiencing, it is difficult to objectify it for the purpose of treatment.

But figuring out the extent of pain a patient feels is vitally important in the realm of pain, the pain clinic. Because the improvement of pain disease is only dependent on the relief of pain felt by the patient.

Therefore, in order to find out the progress and result of treatment, a process of objectively verifying the degree of pain felt by the patient is essential.

As a method for quantifying the degree of pain of a patient, the following method is conventionally used.

Bath (hereinafter referred to as "VAS", visual analogue scale); If you give a 100-cm chair and the most painful pain in your life (e.g., pain in childbirth), say 100. For example, if the position is 76 cm, the patient's pain now is VAS 7.6 (maximum 10.0). It is a very primitive or the most commonly used method.

NLS (hereinafter referred to as "NRS") numerical rating scale; If the patient's 100 most painful pain in life is 100, please state the number of current pain. This method is similar to VAS, but there is a problem in that the emotion or subjectiveness of the patient is involved because the patient judges the numerical value.

Since the above method arbitrarily determines the degree of pain felt by the patient himself, there is a problem that the degree of pain varies from time to time even with the same pain depending on the subjectivity of the patient. Therefore, the conventional method is difficult to use for the purpose and means of treatment because there is no clear objective standard.

This situation has led many to find a way to scientifically quantify pain, but despite the efforts of numerous experts, so far no way has been found to achieve this.

The present invention has been made after a long period of research in the mind of this problem.

Japanese Patent No. 3808492 (2006.05.26)

An object of the present invention is to quantify the pain felt by a patient with an objective criterion in order to solve the above-mentioned conventional problems.

Another object of the present invention is to objectively determine the skin sensitivity or individual skin sensitivity of each part of the body.

Other objects of the present invention will be readily understood through the following description of the embodiments.

According to an aspect of the present invention, the pain input unit that can be added to the human body by dividing the stimulation by the electric device in multiple stages, and the EEG measuring unit for measuring the EEG while adding the stimulus to the human body step by step in the pain input unit And, EEG display unit for displaying the change of the EEG so that the degree of the pain is determined based on the lowest stimulation of the case when the EEG corresponding to the stimulus input to the pain input unit is generated, and the EEG measuring unit A pain recognition display unit for analyzing the information of the stimulus input stage inputted from the pain input unit where the change of the EEG occurs, and calculating the degree of pain as a numerical value; By dividing the stimulus given by dividing into multiple stages, the electrical stimulation of low to high intensity is sequentially In addition, the pain recognition unit is based on the lowest level of stimulation so that the degree of pain is determined in the current n + 1 step and other changes in the previous n stages of EEG, n + 1 is substituted for n It is possible to provide a quantified pain sensitivity measuring device that calculates the degree of pain as a numerical value displayed.

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 Here, the amount of current may be adjusted by varying the voltage.

Here, the amount of current may be adjusted by changing the resistance or by changing the resistance and the voltage.

Here, the pain injection unit may be characterized by imparting a magnetic pole divided into multiple stages by a mechanical device.

Here, the pain recognition display unit for analyzing the information of the stimulus input step injected from the pain input unit where the change in the brain wave caused by the EEG measurement unit may be further added to the pain recognition display unit.

Here, the pain injection portion may include a magnetic pole injection portion for injecting the stimulus into the human body and a material having a flexibility and the mounting rod protruding the magnetic pole injection portion.

In addition, the present invention comprises the steps of: a) attaching the EEG measurement unit to the patient's head and the pain injection unit in a position away from the pain area of the patient, b) step of injecting electrical stimulation through the pain injection unit; c) displaying the change in EEG of the patient according to the stepwise electrical stimulation; and d) applying the electrical stimulation at the current stage based on the lowest stimulus among cases in which an EEG corresponding to the stepped stimulus is generated. The step of d) includes indicating the degree of pain, wherein step d) replaces n + 1 with n in step n + 1, which is the next step after step n where no change in EEG occurs, and in step n, the previous step When EEG and other changes occur, it is possible to provide a quantitative pain sensitivity measurement method that indicates the degree of pain as a numerical value indicating substituted n.
In another embodiment, a) attaching the EEG measurement unit to the head of the subject to measure the skin sensitivity and attaching the pain injection unit to the site to be measured skin sensitivity, and b) the pain injection unit Step of inputting electrical stimulation step by step, c) displaying the change in the brain wave of the subject according to the electrical stimulation, and d) based on the lowest stimulus of the case where the brain wave corresponding to the input step stimulus occurs And displaying the electrical stimulation of the current stage as the skin sensitivity of the skin, wherein step d) replaces n + 1 with n in step n + 1, which is the next step after step n where no change in EEG occurs. In the n-substituted step, when the EEG and other changes occur in the previous n-steps, a quantitative pain sensitivity measuring room indicating skin sensitivity as a value indicating n is substituted. It can provide.

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The present invention quantifies the degree of pain felt by the patient with an objective measure, thereby making it easy to know the progress of the treatment in the treatment of pain.

In addition, the present invention has the effect of objectively know the skin sensitivity according to each part of the body.

In addition, the present invention has the effect of objectively knowing the difference in individual skin sensitivity.

1 is a diagram illustrating a method of analyzing a patient's pain level using an EEG analyzer according to an embodiment of the present invention.
2 is a view showing the configuration of the pain sensitivity measuring apparatus according to an embodiment of the present invention.
Figure 3 is a view showing an embodiment of the pain injection unit of the present invention.
Figure 4 is a view showing another embodiment of the pain injection portion of the present invention.
Figure 5 is a view showing the brain wave shape of the patient when the current in the first step of the embodiment of the present invention.
Figure 6 is a view showing the brain wave changes of the patient when the current of three steps in one embodiment of the present invention.
FIG. 7 is a flowchart illustrating a method of quantifying the degree of pain felt by a patient when an EEG change occurs according to an electrical stimulus generated step by step according to one embodiment of the present invention.
8 is a flowchart illustrating a method of determining the sensitivity of the skin when a change in the EEG occurs in accordance with an electrical stimulation generated step by step in an embodiment of the present invention.

The terminology used herein is for the purpose of describing particular example embodiments only and is not intended to be limiting of the present invention. The first and second or the terms are used only for the purpose of distinguishing one component from another. In addition, singular forms may include plural forms unless the context clearly indicates otherwise.

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings.

Prior to the description of the present invention, a description of the brain waves and a method of measuring the brain waves will be described.

The brain wave is a record of the current generated by the activity of the brain, or the amplification and amplification of it. In 1875, British physiologist R. Keiton first recorded the cortex of rabbits and monkeys. Weak electricity activity from. The case of man was first recorded in 1924 by H. Berger, a German psychiatrist.

Berger inserted two platinum electrodes under the skull defect of a traumatic patient and observed that they could be recorded later by simply placing the electrodes on the scalp. Electroencephalogram (腦電圖, electroencephalogram: EEG) was called. In honor of his achievements, EEG is also known as the Berger rhythm.

EEG represents part of brain function. In view of this, it is currently difficult to judge higher mental phenomena, such as thinking, feelings, and will, from the waveform of brain waves. However, the state of activity of the entire brain, for example, whether you open your eyes or sleep, is fairly accurate in EEG. In addition, when an abnormality occurs in the function of the brain, an abnormal brain wave may appear in response to the abnormal brain function, and in particular, an abnormal waveform called an extreme wave (spike) is indispensable for the diagnosis or treatment of the entire liver.

There are many theories about the mechanism of brain wave generation, such as the spike set-up potential theory and the hypothesis such as the synchronous fluctuations of the brain cortical exciter. The most likely theory is that the dense masses occur. In addition, the rhythm of EEG occurs because a large number of nerve cells work in synchronism, and the circuit that circulates between the part of the thalamus and the non-special nucleus and the cerebral cortex plays an important role. It is said.

EEG is classified as follows according to its frequency and amplitude.

Alpha (α) wave is a representative component of human brain waves, it is a regular wave around 10Hz and appear continuously. The amplitude is about 50 μV on average, the largest recorded in the head and larynx, small in the frontal head.

Alpha waves are produced mainly in peace of mind. Alpha waves are closely related to the development of the brain, the frequency of which is 4-6 Hz in infancy, and then the frequency increases with age, reaching the value of adults around 20 years old.

Beta waves are waves that are faster than alpha waves and predominate in the center or frontal region of the brain. The amplitude is usually around 20μV.

Beta waves are produced mainly during exercise or stress.

Waves with a frequency later than alpha waves are called slow waves, and those with a frequency of 4 to 7 Hz are called theta waves and delta waves below. This was initially observed in patients with brain tumors, but it is not necessarily specific to abnormal brains, and it is quite common in infants, and in addition, EEG, which occurs during sleep in normal adults, is the main component.

Normal people are less likely to see waves later than alpha waves. If a delta (δ) wave appears at the time of stable awakening or theta (θ) wave appears repeatedly, it may be regarded as an abnormality. In this case, the delta wave is seen in brain tumors and cerebrovascular disorders. In addition, the case where the frequency of the beta (β) wave is mainly composed of waves around 8 Hz is abnormal, and in this case, brain function deterioration appears. The beta (β) wave occupies more than 3% of the total case is also abnormal. It also considers abnormally high or low amplitude EEG.

1 is a diagram illustrating a method of analyzing a patient's pain level using an EEG analyzer according to an embodiment of the present invention.

The basic principle and method of the present invention are described as follows.

According to the present invention, when a patient feels pain due to a wound, the pain caused by the newly applied stimulus is relatively less felt due to the wounded area when a new stimulus causing pain is applied to a part other than the pain area. At the point of feeling pain, the brain wave shows a sudden change unlike usual.

This adds a new stimulus that causes pain elsewhere in the human body away from the previous pain-inducing area of the patient who feels pain, gradually increasing from low to high levels, causing the body to feel pain at some point and change in brain waves. The method of finding the viewpoint is used.

In other words, when the brain wave of the patient is examined by adding the stimulus stepwise, when the brain wave changes, the degree of stimulation applied to the point of time is judged based on the degree of pain in the wound site previously existing in the human body.

Therefore, in order to realize the above-described method, the EEG sensor attachment part 132 having the EEG sensor 131 inserted therein is attached to the head of the patient who continues to feel pain as shown in FIG. 1, and is transmitted through the EEG sensor 131. EEG is to be displayed through the EEG display unit 111. Therefore, the EEG measurement unit 130 may be composed of an EEG sensor 131, an EEG measurement unit 132 and the EEG display unit 111 for displaying the EEG transmitted through the EEG sensor 131.

Here, the EEG display 111 may be included in the control unit 110, not the EEG measurement unit 130.

The pain input unit 120 includes a multi-step current generating unit 114 according to the current intensity and a stimulus input unit 121 for generating a stimulus by adding a current, and an input current display unit for detecting and displaying a current intensity step at the time of EEG change. 112.

Here, the multi-step current generator 114 and the input current display unit 112 may be included in the pain input unit 120 or may be included in the control unit 110.

These configurations, of course, should be considered as illustrating the need for such concepts as one embodiment for implementing the apparatus of the present invention. How to implement this can be variously implemented by those skilled in the art by applying a lot of related equipment.

For example, the method for determining the degree of pain of a patient using the pain sensitivity measuring apparatus 100 of the present invention is as follows.

Attach the EEG unit 130 to the head of the patient feeling pain and attach the pain input unit 120 to a part far away from the affected area causing pain of the patient (for example, 'hand'). . Thereafter, the electrical stimulation is generated step by step in the multi-step current generation unit 114, and injected into the patient through the pain input unit 120, and the change in the brain wave is measured by the EEG measurement unit 130. It also quantifies the degree of pain the patient feels with the electrical intensity at the point where the EEG changes occur. Detailed description thereof will be described later with reference to FIG. 7.

In addition, it is also possible to find out the skin sensitivity using the pain sensitivity measuring apparatus 100 of the present invention. Detailed description thereof will be described later with reference to FIG. 8.

2 is a view showing the configuration of the pain sensitivity measuring apparatus according to an embodiment of the present invention.

Pain sensitivity measurement apparatus 100 of the present invention may be composed of a control unit 110, a pain input unit 120 and the EEG measurement unit 130.

The control unit 110 displays the change in the EEG according to the electrical stimulation and performs the function of objectively quantifying the pain felt by the patient. For this purpose, the control unit 110 may include an EEG display unit 111, an input current display unit 112, a pain recognition display unit 113, and a multi-step current generation unit 114.

The EEG display unit 111 is a device for displaying the EEG detected by the EEG sensor 131 with the eyes may include a display device such as a monitor.

The input current display unit 112 displays the intensity of the electrical stimulation (current) to be administered when the current generated by the multi-step current generating unit 114 is administered to the patient through the pain input unit 120.

The pain recognition unit 113 performs a function of quantifying the degree of pain felt by the patient by using the intensity of the electrical stimulation administered to the patient when the EEG change of the patient is detected.

Here, the input current display unit 112 and the pain recognition display unit 113 may include a display device such as a monitor. Or it may be configured to further include a speaker for telling the intensity of the input current or the degree of pain recognition of the patient by voice.

The multi-step current generator 114 performs a function of generating an electrical stimulus. The electrical stimulus may be generated step by step with a difference in intensity. For example, the electrical stimulation can be generated in steps of 0.1 A, 0.2 A, 0.3 A, 0.4 A, 0.5 A, 0.6 A, 0.7 A, 0.8 A, 0.9 A, 1 A with an intensity of 0.1 Ampere (A). To this end, the multi-step current generator 114 may include a voltage divider, a current generator, a variable resistor, a current amplifier, and the like.

Here, the multi-step current generation unit 114 may generate a stepped current by changing the input voltage input to the multi-step current generation unit 114, or generate a step by step by changing the resistance with a constant input voltage. You may.

Alternatively, the current may be generated step by step by varying the input voltage and the resistance input to the multi-step current generator 114.

The pain injection unit 120 performs a function of administering a stimulus causing pain to the patient. The pain injection unit 120 may include a magnetic pole injection unit 121, an input current display unit 112, and a multi-step current generation unit 114.

Here, the input current display unit 112 and the multi-step current generation unit 114 may be included in the pain input unit 120 as described above in FIG. 1 or may be included in the controller unit 110.

The stimulus input unit 121 is directly attached to the skin of the patient to perform a function of injecting the current generated by the multi-step current generation unit 114 to the patient. To this end, the magnetic pole injection portion 121 may be configured in the form of a metal needle.

Although not shown in the drawing, the pain injection unit 120 may inject pain into the patient by mechanical stimulation in addition to electrical stimulation. For example, a mechanical stimulus is introduced using a needle such as a needle. In the case of using mechanical stimulation, a stepped mechanical stimulus is generated by the depth or number of saliva applied to the skin.

Here, in the case where the input current display unit 112 and the multi-step current generation unit 114 are included in the controller unit 110 instead of the pain input unit 120, the pain input unit 120 is well positioned on any part of the human body. It is configured to have structural features that can be attached. The structural features of the pain injection unit 120 will be described later with reference to FIGS. 3 and 4.

The brain wave measuring unit 130 performs a function of measuring brain waves. To this end, the EEG measurement unit 130 is configured to include an EEG sensor 131 and the EEG sensor mounting portion 132.

The EEG sensor 131 is configured to include a sensor device for measuring the EEG.

The EEG sensor attachment unit 132 performs a function for attaching the EEG unit 130 to the head of the patient. To this end, the EEG sensor 132 may be configured to include a nonwoven fabric.

Figure 3 is a view showing an embodiment of the pain injection unit of the present invention.

Pain injection portion 120 may be composed of a magnetic pole injection portion 121 and the mounting table (122).

Stimulus input unit 121 is composed of a plurality of pole needles to perform the function of transmitting the electrical stimulation through the skin of the patient. To this end, the magnetic pole injection portion 121 is made of a metal body having conductivity.

The mounting table 122 is formed of a material having a magnetic pole input unit 121 attached thereto and having flexibility. To this end, the mounting table 122 may be made of nonwoven fabric or flexible silicone. Therefore, the mounting table 122 may be easily attached to an arm or a leg. In addition, the mounting table 122 is configured to protrude the stimulus injection unit 121 into the inner side in contact with the skin, so that the stimulus input unit 121 is in contact with the skin of the patient when the mounting table 122 is attached to the arm or leg, etc. Electrical stimulation can be transmitted through the patient's skin.

Here, the conductive wire 123 is connected to the mounting table 122 to transfer the current generated by the multi-step current generating unit 114 to the magnetic pole input unit 121.

Figure 4 is a view showing another embodiment of the pain injection portion of the present invention.

4 is a further embodiment of the pain injection unit has a structure in which the magnetic pole injection unit 121 protrudes from both ends of the mounting table 122.

Mounting table 122 is made of a material that can be easily bent can be attached anywhere in the body well. That is, the mounting table 122 may be bent like a forceps and easily attached to a desired place. When the attachment table 122 is attached to a part of the body like a forceps, the stimulus injection unit 121 is in direct contact with the skin.

Figure 5 is a view showing the brain wave shape of the patient when the current in the first step of the embodiment of the present invention.

For example, if a current having a difference in intensity of 0.1 A is generated up to seven steps in a step, the current generated in the first step is 0.1 A and the current generated in the second step is 0.2 A, and the step is 0.1 A. In increments of seven, a current of 0.7A is generated.

In FIG. 5, when the current generated in step 1 is administered to the patient at regular time intervals, the brain wave of the patient is shown. There is no change in brain wave in the current generated in step 1. FIG.

In this case, it can be estimated that the patient's continuous pain is more than the first stage of pain that is felt when a 0.1A current is administered.

Figure 6 is a view showing the brain wave changes of the patient when the current of three steps in one embodiment of the present invention.

As shown in FIG. 5, when the change of brain wave does not occur when the electrical stimulation generated in step 1 is administered to the patient, the next two levels of electrical stimulation are generated and administered to the patient. If the change of EEG does not occur even when the electrical stimulation generated in step 2 is administered to the patient, then the third step is generated and administered to the patient.

Figure 6 shows the changes in the EEG when the patient was administered three electrical stimulation stages. Therefore, it can be inferred that the pain that the patient has been feeling is the degree of pain corresponding to the third stage.

That is, in the meantime, since the patient was feeling pain in three stages, if the stimulus of lower level was not applied, the EEG did not change. Change will occur.

FIG. 7 is a flowchart illustrating a method of quantifying the degree of pain felt by a patient when an EEG change occurs according to an electrical stimulus generated step by step according to one embodiment of the present invention.

S700 is a step of attaching the EEG sensor to the head of the patient who is feeling pain.

Step S710 is a step of attaching the stimulus input to the site far from the pain-inducing area of the patient.

Here, step S710 may be performed before step S700 or two steps may be simultaneously performed.

Step S720 is a step of generating a current corresponding to n steps in the multi-step current generation unit and injecting a current corresponding to the n steps generated through the stimulus input unit to the patient.

Where n means a specific step. The reason for using the electrical stimulation corresponding to the specific n-stage is that if the pain felt by the patient is severe, the electrical stimulation of the intermediate stage can be generated step by step, rather than the lowest electrical stimulus. Because.

Step S730 is a step to determine whether a change in EEG (change of brain waves) occurs with respect to the electrical stimulation applied in step S720. If there is no change in the EEG, go to step S740 and replace n + 1 steps with n steps. Thereafter, go to step S720 to generate an electrical stimulus corresponding to the substituted n step.

In the step S740, when the EEG change occurs in step S730, the degree of pain felt by the patient is quantified based on the stimulus for generating the EEG change.

For example, suppose that n is 1 in S720, that is, when a current corresponding to step 1 is generated. Replace 2, which is 1 + 1, with n. Accordingly, since n becomes 2 in step S720, electric stimulation (current in two steps) corresponding to step 2 is generated. Thereafter, when the electrical stimulus corresponding to the second stage is applied, if the change in the patient's EEG occurs, the degree of pain felt by the patient may be digitized as 2.

8 is a flowchart illustrating a method of determining the sensitivity of the skin when a change in the EEG occurs in accordance with an electrical stimulation generated step by step in an embodiment of the present invention.

S800 is a step of attaching the EEG sensor to the head of the person who wants to measure the skin sensitivity.

Step S810 is a step of attaching the stimulus input to the site to measure the skin sensitivity.

Here, step S710 may be performed before step S700 or two steps may be simultaneously performed.

Step S820 is a step of generating a current corresponding to the n step in the multi-step current generation unit and injecting the current corresponding to the n step generated through the stimulus input unit to the patient.

Where n means a specific step. The reason for using the electrical stimulation corresponding to the specific n-stage is that if the pain felt by the patient is severe, the electrical stimulation of the intermediate stage can be generated step by step, rather than the lowest electrical stimulus. Because.

Step S830 is a step of checking whether changes in EEG (change of brain waves) occur with respect to the electrical stimulation applied in step S820. If the EEG does not change, go to step S840 and replace n + 1 steps with n steps. Thereafter, go to step S820 to generate an electrical stimulus corresponding to the substituted n-step.

In step S840, when the EEG change occurs in step S830, the degree of skin sensitivity is quantified based on the stimulus for generating the EEG change.

For example, suppose that n is 1 in step S820, that is, when a current corresponding to step 1 is generated, when there is no change in the brain wave of the patient when the current corresponding to the generated step 1 is input to the patient. 2 which is 1 + 1 is substituted by n. Accordingly, since n becomes 2 in step S820, electric stimulation (current in step 2) corresponding to step 2 is generated. Afterwards, when the electrical stimulus corresponding to the second stage is applied, if the EEG of the patient changes, the skin sensitivity of the site can be quantified as 2.

When skin sensitivity is measured, it means that skin sensitivity corresponding to a low level electrical stimulation is more sensitive.

Although the above has been described with reference to embodiments of the present invention, those skilled in the art may variously modify the present invention without departing from the spirit and scope of the present invention as set forth in the claims below. And can be changed.

100: Quantified pain sensitivity measuring device.
110: control unit
111: EEG display unit
112: input current display unit
113: pain recognition display
114: multi-step current generator
120: pain injection unit
121: magnetic stimulation unit
122: mounting table
123: lead wire
130: EEG measuring unit
131: EEG sensor
132: EEG sensor attached part

Claims (7)

Pain injection unit for dividing the stimulation by the electric device into multiple stages to add the individual stimulus to each human body in sequence;
An electroencephalogram measuring unit for measuring an electroencephalogram while adding stimulation to the human body step by step in the pain input unit;
An EEG display unit displaying a change in the EEG so that the degree of the pain is determined based on the lowest stimulus among cases in which EEG corresponding to the stimulus input by the pain input unit is generated;
And a pain recognition display unit for analyzing the information of the stimulus input step inputted from the pain input unit where the change of the brain wave by the EEG measurement unit occurs and calculating the degree of pain as a numerical value.
The pain injection section
By dividing the stimulus given by dividing the amount of current input from the electrical device into multiple stages, the electrical stimulation of low intensity to high intensity is sequentially given to the human body,
The pain recognition display unit
When the current n + 1 stage is different from the previous n stages of EEG so that the degree of pain is determined based on the lowest stage of stimulation, the degree of pain is calculated as a value representing the substituted n of n + 1. Quantified pain sensitivity measurement device.
delete The method of claim 1,
Quantifying the pain sensitivity measurement device, characterized in that for adjusting the amount of the current by changing the voltage.
The method of claim 1,
Quantifying the pain sensitivity measurement device characterized in that for adjusting the amount of the current by changing the resistance, or by changing the resistance and voltage.
The method of claim 1,
The pain injection section
A stimulus input unit for injecting the stimulus into the human body; And
Attachment is made of a flexible material and protruding the magnetic pole injection portion; Quantified pain sensitivity measurement device comprising a.
a) attaching the EEG to the patient's head and attaching the pain input to a location away from the pain area of the patient;
b) stepwise inputting electrical stimulation through the pain input;
c) displaying the EEG change of the patient according to the electrical stimulation; And
d) displaying the electrical stimulation of the current stage based on the lowest stimulus among the cases where the EEG corresponding to the injected staged stimulus is generated, and the degree of the corresponding pain;
In step d), n + 1 is replaced with n in step n + 1, which is the next step after step n where no change in EEG occurs, and when n is changed from the previous step in step n, the substituted n Quantitative pain sensitivity measurement method that indicates the degree of pain as a numerical value indicating.
a) attaching an EEG measurement unit to a head of a subject to measure skin sensitivity and attaching a pain injection unit to a site to measure skin sensitivity;
b) stepwise inputting electrical stimulation through the pain input;
c) displaying the EEG change of the subject according to the electrical stimulation; And
d) displaying the electrical stimulation of the current stage as the skin sensitivity of the skin based on the lowest stimulus among the cases where the EEG corresponding to the injected staged stimulus occurs;
In step d), n + 1 is replaced with n in step n + 1, which is the next step after n, in which no change in EEG occurs. Quantitative pain sensitivity measurement method for indicating skin sensitivity as a number indicating n.

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