KR102049881B1 - Feed additive composition for improving or preventing pig's gastric ulcer comprising Pineapple pomace and eppermint essential oil - Google Patents

Abstract

The present invention relates to a pig feed additive composition and, more specifically, to a functional feed additive composition which can treat and alleviate gastric ulcer in pig by including pineapple pomace and peppermint essential oil as active ingredients. When the pineapple pomace and the peppermint essential oil of the present invention is supplied as a feed additive, the body temperature of pigs raised in pigsty of the high temperature during summer is substantially reduced and the gastric ulcer in pig is effectively alleviated, thereby being usefully used as a functional feed additive composition. In particular, the pineapple pomace and the peppermint essential oil are natural and have long-term safety benefits.

Description

Feed additive composition for improving or preventing pig's gastric ulcer comprising Pineapple pomace and eppermint essential oil

The present invention relates to a pig feed additive composition, and more particularly, to a functional feed additive composition which can treat / improve gastric ulcers in pigs including pineapple foil and peppermint essential oil as active ingredients.

Ulcers are commonly found in the digestive tract of livestock. The most common sites for gastric ulcers in pigs are the pars esophagea and the gastric junction. Gastric ulcers can occur over any age, especially at 3-6 months of age. Clinical symptoms are manifested by blood loss due to ulcerative lesions. Slow blood loss can cause anemia, such as paleness, lethargy, weakness, increased respiratory rate, and loss of appetite. Stomach bleeding may be observed due to gastric bleeding. Some pigs may also have symptoms of abdominal pain, such as teething or back flexion, vomiting, and body temperature generally lower than normal. Pigs died of acute gastric ulcers have a very pale character due to rapid blood loss.

There are many factors (gender, genotype, season, fine grains, types of ingredients, feeding time, and emissary) of gastric ulcer, and it is reported that many cases of gastric ulcer occur especially in hot and humid summer due to high temperature stress. It is becoming. The distribution of sweat glands in pigs is limited to the nose and anus, making it difficult to control the body temperature against high temperatures. As the average temperature rises due to global warming, the damage of high temperature stress on the pig industry is increasing.

The gastric ulcer is a significant lesion that causes mortality in growing piglets and sows, causing growth delays, and thus economic losses during mortality. Thus, a decrease in the farming capacity of summer farmers directly leads to a loss of profits of farmers.

Therefore, the present inventors have studied to find a feed additive material that can reduce or improve the occurrence of gastric ulcers caused by high-temperature stress in summer, when the pineapple gourd and peppermint essential oil is supplied as a feed additive, the body temperature of the pigs actually raised in pigs The present invention was completed by confirming that it can effectively reduce and improve gastric ulcer in pigs.

Korea Patent Registration No. 10-0144793 Korean Patent Registration No. 10-1417905 Korean Patent Publication No. 10-2018-0061441

Therefore, it is an object of the present invention to provide a feed additive composition for pigs with excellent activity to reduce or improve the occurrence of gastric ulcers due to high temperature stress while safe for livestock even after long-term use using natural materials.

In order to achieve the object of the present invention as described above,

The present invention provides a feed additive composition for improving gastric ulcer in pigs comprising pineapple foil and essential oils as active ingredients.

In one embodiment of the present invention, the essential oil may be peppermint essential oil.

In one embodiment of the present invention, the pineapple and essential oils may be mixed in a weight ratio of 15: 1-2.

Of the present invention In one embodiment, the composition may be added to the feed at 15 to 17% by weight.

The present invention also provides a method for preventing or ameliorating gastric ulcer in swine, comprising feeding the composition to swine.

When the pineapple foil and peppermint essential oil of the present invention are supplied as a feed additive, it can substantially reduce the body temperature of pigs raised in pigs at high temperature in summer and effectively improve gastric ulcer in pigs, which is useful as a functional feed additive composition. Can be used. In particular, pineapple and peppermint essential oils are natural and have long-term safety benefits.

1 is a photograph showing the critical temperature of the upper limit and the lower limit according to the weight of the pig.

The present invention is characterized by providing a feed additive composition for improving gastric ulcer in pigs comprising pineapple foil and essential oils as active ingredients.

As used herein, the term “pineapple watermelon” refers to the residue left after squeezing out pineapple juice.

'Essential oil' referred to herein refers to an essential oil (essential oil) extracted from the leaves, stems, shells, petals, roots, etc. of aromatic plants grown in nature or cultivated organically, the human-use essential oil is about 70 It is a species and can be used as a single oil or a mixture of two or three kinds to achieve a sufficient effect with a minimum amount of use depending on the purpose of use.

The present inventors studied to find a feed additive material that can reduce or improve the occurrence of gastric ulcers caused by high temperature stress in summer, and as a result, the feed additive composition containing pineapple gourd and essential oil is a pig that is raised in pigs at high temperature in summer. It was the first time to reduce body temperature and effectively improve stomach ulcers in pigs.

Therefore, the composition of the present invention comprising pineapple foil and essential oils as an active ingredient can be usefully used as a composition material applied to livestock or pet animal feed, and particularly preferably applied to feed of pigs subjected to high temperature stress in summer.

In one embodiment of the present invention, the essential oil is oregano (oregano), thymol (thymol), grapefruit (Citrus paradise), Nerori (Citrus aurantium. Vulgaris), Melaleuca viridiflora, lavender (Lavendula angustifolia), Lime (Citrus aurantifolia), Lemon (Citrus limonum), Lemongrass (Cymbopogon citratus), Lemon balm (Melissa, Melissa officinalis), Rose (Rosa centifolia, Rosa damascena, Rosa gallica), Rosemary (Rosemarinus officinalis), Rosewood (Aniba) Rosaeaodora, Lindenbloom (Tilia europaea), Marjoram (Origanum marjorana), Mandarin (Citrus madurensis), Myrtle (Mytus communis), Myrrh (Commiphora myrrha), Violet (Viola odorata), Basil (Ocimum Basilicum), Verbena (Lippia citriodora) ), Birch (Betula alleghaniensis (yellow), B. pendula (silver) B. lenta (cherry)), Bergamot (Citrus bergamia), Bay (Laurus nobilis), Vetiver (Andropogon muricatus), Benzoin (Styrax benzoin) , Cyprus (Cupressus sempervirens), sandalwood (Santalum album), Cinnamomonn zeylanicum, Cedarwood (Juniperus virginiana (Red) Cedrus atlantica (white)), Citronella (Cymbopogon nardus), Orange (Citrus auranthium, Citrus vulgaris, Citrus cinesis), Eucalyptus globulus (Eucalyptus globulus) ), Ylang Ylang (Cananga odorata), Jasminum grandiflorum, Geranium (Pelargonium graveolens), Juniperberry (Juniperus communis), Ginger (Zingiber officinale), Elettaria cardamomum, Chamomile (Anthemis nobilis, Roman chamomile) Melaleuca leucadendron, Cinnamomun camphora, Salvia sclarea, Thymus vulgaris, Citrus reticulate, Melaleuca alternifolia, Cymboopogon martini, Pogoste one or more essential oils selected from the group consisting of patchouli, Cetrus vulgaris, Peppermint (Mentha piperita), Frankinense (Frankincense, Boswellia carteri) and Hyssopus officinalis, Preferably peppermint essential oil.

Feed additive composition of the present invention may be added in an amount of 15 to 17% by weight based on 100 parts by weight of feed, wherein pineapple foil and essential oil may be mixed in a weight ratio of 15: 1-2.

In addition, the present invention provides a method for preventing or improving gastric ulceration in swine, comprising feeding to a pig a feed additive comprising pineapple foil and essential oil as an active ingredient.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are intended to illustrate the present invention more specifically, but the scope of the present invention is not limited to these examples.

< Example  1>

Feed and feed additive preparation

<1-1> Cultivation money  Feed preparation

In the present invention, a commercial feed (IMMUNE STAR raised pig feed, AA67R0146) was purchased from the AT feed (AT Immune Inc) and prepared.

<1-2> Pineapple gourd  Ready

Pineapple gourd used in the present invention was purchased feed material through Korea Dairy, squeezed pineapple juice and the remaining residues were used in powder form by drying at low temperature.

<1-3> peppermint Essential  Oil preparation

Peppermint essential oil (697653187) used in the present invention was purchased from a herb shop.

< Example  2>

Cultivation money  Formulation feed and trial design for pay

<2-1> Preparation of Basic Feed and Feed Additives

The present inventors prepared IMMUNE STAR cultivated pig feed (AT Immune Inc, AA67R0146) as a basic feed in order to evaluate the effect of improving the stomach ulcer by the addition of pineapple foil and peppermint essential oil in the cultivated pig feed. On the other hand, pineapple foil added in the feed was squeezed pineapple juice and the remaining residues were used in powder form by drying at low temperature; Peppermint essential oil was purchased from a herb shop.

<2-2> Test Animal and Test Design

The three-way hybrid [Landrace × Yorkshire × Duroc] hog pigs were disclosed, weighed 60 kg at the start of the test, and were tested for 3 months. The test design consists of 1 × 3 experimental design: 1) T1 (April, May, October, Basic Feed), 2) T2 (June-August, Basic Feed), 3) T3 (June-August, Basic Feed + Pineapple gourd 15% + peppermint oil 1.5%), three treatments, 60 batches per treatment. At this time, 20 heads were placed in each month for each treatment section, and the results were obtained by adding up three months for each treatment section.

Test design Blended raw materials
(Wt% as-fed) Treatment T1 (April, May, October) T2 (June-August) T3 (June-August) Basic feed 100 100 100 Additive Pineapple gourd - - 15 Peppermint Essential Oil - - 1.5 * Note: Pineapple foil and peppermint essential oil added to the basic feed means the weight percentage is 100% by weight based on the basic feed.

< Example  3>

On pork Pineapple gourd  And peppermint Essential  Gastric ulcer effect by oil supplementation

In order to measure the effect of improving gastric ulcer, slaughtered the treated group fed the feed for each month on the 100th day, and then obtained gastrointestinal tract to evaluate the degree of gastric ulcer induction through observation of the ducts. It was based on. At this time, the analysis was carried out by Professor Cho Jin-ho's research team in Chungbuk National University.

On the other hand, the body temperature photographs of pigs in each treatment group were photographed at all times using a thermal imaging camera (product name: KIR-80N, manufacturer: KAVAS Electronics, purchased from UIT) to observe changes in body temperature.

Clinical Symptoms of Gastric Ulcer According to Score Item Picture Clinical symptoms Score0

-The color around the cooking utensils is clear, and the epidermis does not come up.
-Less bile secretion and excessive pollution. Score1

-The epidermis around the cooking utensils rises (<2mm). Score2

-The epidermis around the cooking utensils is raised (> 2mm).
-Skin color around eating utensils becomes pale.
Excessive biliary secretion begins (epidermal yellow). Score3

-Erosion is found. Score4

Ulcers are found around the food utensils. Score5

The ulcer shows a connection between the surrounding tissues after cells have been eliminated.

As a result, as shown in the following [Table 3], the stomach ulcer disease of the pig was found to be severe at the high temperature stage, pineapple foil and peppermint essential oil was added to the basic feed compared to the treatment group T2 fed the basic feed at the high temperature stage It was confirmed that the gastric ulcer is effectively improved in the treatment group T3. In addition, as a result of measuring the body temperature of the pigs by treatment, it was confirmed that the body temperature reduction effect appeared in the T3 treatment.

Effects of Pineapple Foil and Peppermint Essential Oil on Body Temperature and Reduction of Gastric Ulcer Item 4,5, Oct 6,7,8 month Pineapple gourd 15% + peppermint oil 1.5% Average temperature (℃) 16.7 26.9 26.9 Average pig temperature (℃) 26.7 37.8 37.8 Score specimen ratio (%) specimen ratio (%) specimen ratio (%) 0 17 28.3 6 10 14 23.3 One 23 38.3 17 28.3 22 36.7 2 16 26.7 18 30 15 25 3 One 1.7 5 8.3 4 6.7 4 One 1.7 7 11.7 2 3.3 5 2 3.3 7 11.7 3 5 total 60 100 60 100 60 100 Body temperature

So far I looked at the center of the preferred embodiment for the present invention. Those skilled in the art will appreciate that the present invention can be implemented in a modified form without departing from the essential features of the present invention. Therefore, the disclosed embodiments should be considered in descriptive sense only and not for purposes of limitation. The scope of the present invention is shown in the claims rather than the foregoing description, and all differences within the scope will be construed as being included in the present invention.

Claims (5)

As a feed additive composition for improving gastric ulcer in pigs,
The composition comprises pineapple foil and peppermint essential oil as an active ingredient,
The pineapple foil and peppermint essential oil is a feed additive composition for improving stomach ulcers of pigs, characterized in that mixed in a weight ratio of 15: 1-2. delete delete The method of claim 1,
The composition is a composition, characterized in that added to the feed at 15 to 17% by weight. A method for preventing or improving gastric ulceration in swine, comprising feeding the composition of claim 1 to swine.

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