KR102025304B1 - Composition for preventing loss of components of hair, skin, or fiber - Google Patents

Abstract

A composition of the present invention relates to a composition comprising a cationic cellulose polymer, a polar ion and/or a crosslinking mediator component and a carbodiimide-based compound. The composition of the present invention can effectively prevent the loss of hair, skin or fiber components during the cleaning process, thereby maintaining the health of the hair, skin or fibers, and particularly has an effect of improving the properties such as strength, gloss, and thus can be used in a variety of products, such as shampoo, detergent, cosmetics.

Description

COMPOSITION FOR PREVENTING LOSS OF COMPONENTS OF HAIR, SKIN, OR FIBER}

The present invention relates to a composition capable of preventing the loss of the components constituting the skin, hair or fibers.

The main purpose of cleaning agents such as skin and hair is to remove grease. To this end, most detergents use surfactants. In particular, anionic surfactants are widely used because they have an excellent effect on cleaning. However, surfactants suffer from the loss of lipids contained in hair or skin constituents, in particular hair, skin, and the like.

Lipids in the skin act as a skin barrier that connects the stratum corneum, protecting the keratin from the external environment and preventing water evaporation. When lipids are lost in the skin, there is a problem that the stratum corneum is lifted up and the skin texture worsens.

Hair lipids are supplied from sebaceous glands, which act as a hydrophobic coating that protects the hair and scalp from water. Many studies have shown that sebum has a moisturizing effect on the scalp as it does on the skin. Hair lipids affect hair texture and have additional functions such as ease of combing, softness, smoothness or gloss of hair, reduced friction on the surface of the hair, antistatic or hair protection. Loss of hair lipids causes problems such as hair softness, reduction of gloss, etc., damage to hair by static electricity or friction, and the like.

Accordingly, in order to solve the problem of dissolving internal components such as hair, skin, and the like, especially lipids, caused by surfactants, a market for cleaners including natural cleansing ingredients has recently been formed, excluding the use of synthetic materials. However, in this case, there is a limit that the cleaning effect is remarkably inferior by excluding the anionic surfactant.

On the other hand, in order to solve the problem caused by the loss of hair / skin lipids, the patent US2004 / 0156810 is a technology for infiltrating organic acids and strengthening the shine and hair inside the hair. The stiffening technique (Journal of Sol-Gel Science and Technology 79, (2016), 359) and the technique of infiltrating fatty alcohols into the hair with a gel network (International Journal of Cosmetic Science, 39, (2017) 543) have been reported. Since these components maintain the strengthening of the hair by artificially penetrating the synthetic compound into the hair, which is not an inherent component of the hair, there is still a problem of causing a feeling of rejection to the consumer and failing to protect the hair or the skin itself.

In addition, products have been developed to solve the problem of lipid loss by infiltrating the fatty acids contained in the hair in the shampoo, but if the fatty acid content of the cleaning agent exceeds 0.5%, it is a bad idea to adsorb grease on the hair during the cleaning process. The result is that if the content is lower than 0.5%, the fatty acid does not penetrate into the hair during the washing process and is washed away by water, and thus still cannot solve the problem of lipid loss.

Therefore, there is still a need for the development of a technique that can prevent the removal of components such as hair, skin, etc. by the cleaning agent.

Under the background described above, the present inventors have conducted studies to solve the problem of the loss of the components constituting the hair, skin or fibers in the washing process, thereby revealing the mechanism by which the components of the hair, skin or fibers are lost, and the present invention. The composition comprising a crosslinking mediator and a carbodiimide-based compound, a cationic cellulose polymer and / or a polar oil can be effectively prevented from disappearing these components, thus completing the present invention.

In order to achieve the above object, the present invention provides a crosslinking mediator and a carbodiimide compound having a carboxyl group or an amine group; Cationic cellulose polymers; And it provides a composition for preventing hair, skin or fiber component loss comprising any one selected from the group consisting of polar oil.

The present invention also provides a composition for hair, skin or fiber treatment comprising the composition.

The present invention also provides a cleaning composition comprising the composition.

In addition, the present invention provides a cosmetic composition comprising the composition.

The composition according to the present invention prevents the loss of the components of hair, skin or fibers occurring during the cleaning process, thereby protecting the hair, skin or fibers from damage and irritation resulting from the cleaning process, and has an effect of maintaining health. . Therefore, the composition of the present invention can be usefully used in cleaning agents, cosmetics and the like.

1 is a schematic diagram showing the mechanism by which components in hair lost by anionic surfactants are lost. Group A is a low hydrophobic or amphiphilic component of the hair internal component, and group B means a component having hydrophobicity among the hair internal component.
2A and 2B are graphs showing values of quantifying lipid loss characteristics in hairs by washing with a gas chromatogram according to an embodiment of the present invention, as relative values (%) of untreated hairs. From Experiment No. 1 to Experiment No. 9 were sequentially as follows: C ₁₄ : Myristyl acid, C ₁₆ : Palmitic acid, C ₁₈ : Stearic acid, C _{18 = 1} : oleic acid, cholesterol (Cholesterol), squalene (Squalene), C ₁₄ -C ₁₄ lipid, C ₁₄ -C ₁₆ lipid, C ₁₆ -C ₁₆ , C ₁₈ -C ₁₆ lipid.
Figure 3 is a graph showing the results of confirming the effect of preventing lipid loss in hair by the treatment of the composition according to an embodiment of the present invention. Group A is a lipid having low hydrophobicity or amphipathicity among the hair internal components, and group B means a lipid having hydrophobicity among the hair internal components.

The present invention provides a composition for preventing hair, skin or fiber component loss.

The composition for preventing hair, skin or fiber component loss of the present invention includes a crosslinking mediator having a carboxyl group or an amine group and a carbodiimide-based compound; Cationic cellulose polymers; And it may include one or more selected from the group consisting of polar oil.

In addition, the composition for preventing hair, skin or fiber component loss of the present invention includes a crosslinking mediator having a carboxyl group or an amine group and a carbodiimide compound and a cationic cellulose polymer; Polar oils; Or cationic cellulose polymers and polar oils.

As used herein, the term "hair, skin or fiber component" means a component constituting hair, skin or fiber. More preferably, the hair, skin, or fiber inside the composition or contained within, that is, means an internal component. In the description of the present invention, it can be used interchangeably such as internal components, components or components in hair, skin or fibers. Specific examples of the internal components include keratin proteins, lipids, moisture and trace elements, but are not limited thereto. The trace element includes but is not limited to nickel, titanate, iron, molybdenum, copper, cobalt, iron and the like. In the cleaning process, the internal components of hair, skin or fibers are lost due to frictional pressure, adsorption by surfactants, etc., thereby causing the hair, skin or fibers to become rough or loose. In addition, the strength is weakened by the loss of the internal components, the problem of breaking and cracking also occurs. The composition of the present invention has the effect of preventing such internal components from being lost in the cleaning process, thereby keeping the hair, skin or fibers healthy.

The composition of the present invention crosslinks the components in the hair, skin or fibers to prevent elution by diffusion to the outside, and forms a protective film for the surfactant in contact with the outside during the cleaning process, so that the surfactant penetrates inside It is possible to prevent the loss of internal components through this. In particular, in one specific embodiment, when treating the hair composition according to an embodiment of the present invention, it was confirmed that the loss of lipids in the hair is remarkably prevented, and thus the hair is further strengthened, in this aspect the inner The component may be a lipid and the composition of the present invention may be a composition for preventing the loss of lipids in hair, skin or fibers.

The inventor of the present invention divides the mechanism of loss of lipids among the internal components into two, as confirmed in Test Example 1, and hydrophobic lipids having hydrophobic properties are lost together by migration of surfactant micelles in hair, skin, or fibers. In the case of amphiphilic or relatively low hydrophobic lipids, the diffusion of the lipids from the inside of the hair toward the surface of the hair occurs in a mechanism that predicts the loss of lipid components eluted out of the hair in combination with the surfactant and prevents them. As a result of continuing the risk studies, a crosslinking mediator having a carboxyl group or an amine group and a carbodiimide compound; Cationic cellulose polymers; And / or it was confirmed that it can effectively prevent the loss of lipids using polar oil to complete the present invention.

Hydrophobic lipid group in the present invention means having a relatively high hydrophobicity compared to other lipids, for example, squalene (Squalene), wax ester (Wax ester), but is not limited thereto. In addition, amphiphilic or relatively low hydrophobic groups of lipids include fatty acids (myristyl acid (C ₁₄ ), palmitic acid (C ₁₆ ), stearic acid (C ₁₈ ), oleic acid (Oleic acid, C _{18 = 1} ), cholesterol (Cholesterol), cholesterol, and the like, but is not limited thereto.

The composition of the present invention may include a crosslinking mediator having a carboxyl group or an amine group and a carbodiimide-based compound.

The crosslinking mediator component having the carboxyl group or the amine group refers to a component that serves to form crosslinks between amino acids in the hair, skin, or fibers, and directly bonds with the amino acids to form crosslinks or bonds between amino acids. It can act as an intermediary to do so. Specifically, it may bind to a carbodiimide-based compound to form a crosslink between internal components, or one side of the intermediate component may directly bind to the internal component, and one side may bind to the carbodiimide-based compound to Crosslinks can be formed. The composition of the present invention comprising a crosslinking mediator having a carboxyl group or an amine group and a carbodiimide-based compound crosslinks amino acids in the hair, skin, or fiber, and the internal components diffuse to the surface or outside during the washing process and disappear. Can be effectively prevented. In particular, crosslinking of the internal components of hair, skin, or fibers can effectively prevent the loss of hydrophobic internal components.

As confirmed by the specific test example, when washing was performed 10 times using the conventional washing liquid, 60% of the lipids in the hair were lost, but crosslinking between the internal components of the hair was carried out using the mediator and the carbodiimide-based compound. In the case of the formation, it can be seen that the degree of loss of the hydrophobic lipid components is lowered even after 10 washings.

The crosslinking mediator having a carboxyl or amine group in the present invention includes all that can react with biological amino acids on the protein surface of hair, skin or fibers, including carboxyl or amine groups. Specifically, the crosslinking mediator having a carboxyl group or an amine group may include at least one selected from the group consisting of natural extracts, amino acids, peptides, proteins, polymers, silicones, fatty alcohols, fatty acids, waxes, esters, and derivatives thereof. Including but not limited to. The crosslinking mediator of the present invention forms covalent bonds with protein residues (thiols, hydroxyls, carboxyls or amines) of hair, skin or fibers, thereby enabling crosslinking between internal components, and also carbodiimide-based It is characterized by increasing the reaction efficiency with the compound so that crosslinking between internal components is more efficiently formed.

The natural extract, for example, honggyeongcheon extract, camellia leaf extract, ursolic acid, gall bladder extract, seaweed extract, sunflower seed extract, red ginseng extract, ginseng extract, rhubarb extract, marigold extract, birch sap, birch extract, flower extract, Cheonna Extract, Bergamot Extract, Cypress Extract, Red Ginseng Extract, Red Ginseng Extract, Produce Extract, Centella Extract, Rhubarb Extract, Red Ginseng Extract, Femo Extract, Lily of the Valley Extract, Honeycomb Extract, Cassis Extract, Pomegranate Extract, Lemon Extract, Pine Needle Extract, Green Tea Extract It may include, brokerage extract, honey extract, cranberry extract, berry extract, lavender extract, lentil extract, ginger water extract, etc. The protein and peptide include cheonjamsil, silk, polylysine, seaweed, wool and hair , Proteins and peptides obtained from wheat, and the like.

The amino acids include glycine, alanine, valine, leucine, isoleucine, threonine, serine, cysteine, cystine, methionine, aspartic acid, asparagine, glutamic acid, diyodtyrosine, lysine, arginine, histidine, phenylalanine, tyrosine, tryptophan, proline, oxy Proline and the like.

The peptide includes a peptide consisting of 2 to 200 amino acids, and the protein includes keratin, collagen, gelatin, plant protein or hydrolysates thereof. The keratin is preferably hydroylzed keratin, and more preferably has a molecular weight of 200 to 150,000 Da.

The polymers include linear and branched chain and network polymer compounds having a molecular weight of about 1 million to 1 million, and various substituents of double bonds or ring structures between these carbons may be added as necessary. Inclusion cases are also included in the present invention. Groups of -COONa, -COOK, -COOH, -NH ₂ , -NHR, -NR ₂ , -Cl, -Br, -I, or -F to facilitate the reaction for attaching a bioreactive functional group to either end of the molecule It is preferred to include at least one moiety in the molecule that has a reactivity to attach the same bioreactor. More preferably, it is a linear or branched chain polymer having 100 to 500,000 carbon atoms, and -COONa, -COOK, -COOH, -NH2, -NHR, to facilitate a reaction for attaching a bioreactive functional group to either terminal of the molecule. Compounds containing at least one moiety in the molecule having a reactivity such as —NR 2, —Cl, —Br, —I, or —F group can be used. For example, amino acid polymers such as polylysine, polyamine polymers, polycarboxylic acid polymers, methacryloylethyl Betaine / Methacrylate Copolymer, octylacrylamide / acrylate / Amphoteric polymers such as butylaminoethyl methacrylate copolymer (Octylacrylamide / Acrylates / Butylaminoethyl Methacrylate Copolymer) or polyvinylpyrrolidone, PVP / VA copolymer, PVP / dimethyl Aminoethyl methacrylate copolymer (PVP / Dimethylaminoethylmethacrylate Copolymer), nonionic polymers such as polyurethane and Acrylate Methacrylate Copolymer, V / crotonate / vinyl neodecanoate copolymer ( Anionic polymers such as VA / Crotonates / Vinyl Neodecanoate Copolymer) It may be, but is not limited thereto.

Examples of the silicones include dimethicone, trimethicone, phenyltrimethicone, amodimethicone, amodiphenyltrimethicone, amodi-penta phenyltrimethicone, dimethylpolysiloxane, methylphenylpolysiloxane, and decamethyl. Cyclopentasiloxane, methyltrimethicone, phenyltrimethicone, methicone, cyclomethicone, alkylmethylsiloxane, dimethicone copolyol, trimethylsilylamodimethicone type compounds, but is not limited thereto.

The fatty alcohols are chain and branched fatty alcohol compounds having about 10 to 50 carbon atoms, for example, lauryl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, behenyl alcohol, etc. It is not limited.

The fatty acid is a chain and branched fatty acid compound having about 10 to 50 carbon atoms, for example, 18-methyl eicosanoic acid, lauric acid, stearic acid, isostearic acid, etc., but is not limited thereto.

The waxes may be, for example, candela wax, carnauba wax, rice wax, beeswax, lanolin, ozokerite, ceresin wax, paraffin wax, microcrystalline wax, polyethylene wax, and the like, but are not limited thereto. .

The esters are, for example, isopropyl myristate, butyl myristate, isopropyl palmitate, ethyl stearate isopropyl linoleate, decyl myristate, cetyl myristate, cetyl palmitate, hydrogenated polyisobutene ( Hydrogenated polyisobutaine) and the like, but is not limited thereto.

In the present invention, the carbodiimide-based compound is meant to include all compounds including an N = C = N structure, and more specifically, N, N'-methylene-bis- (4-isocyanatocyclohexane)- , Homopolymer, polyethylene glycol mono-Me-ether-blocked (N, N'-methylene-bis- (3-isocyanatocyclohexane)-, homopolymer, polyethylene glycol mono-Me-ether-blocked), N, N ' Dicyclohexylcarbodiimide (N, N'-dicyclohexylcarbodiimide), N, N'-diisopropylcarbodiimide (N, N'-diisopropylcarbodiimide), N-ethyl-N '(3-dimethylaminopropyl) N-ethyl-N '(3-dimethylaminopropyl) carbodiimidehydrochloride, N-cyclohexyl, N'-isopropylcarbodiimide, N-tert-butyl, N' N-tert-butyl, N'-methylcarbodiimide, N-tert-butyl, N'-ethylcarbodiimide, N, N'-di Cyclopen N-N'-dicyclopentylcarbodiimide, bis [[4- (2,2-dimethyl-1,3-dioxolyl)] methyl] carbodiimide (bis [[4- (2,2-dimethyl -1,3-dioxolyl)] methyl] carbodiimide), N-ethyl, N-phenylcarbodiimide, N-phenyl, N-isopropylcarbodiimide (N-phenyl, N -isopropylcarbodiimide) and derivatives thereof, but is not limited thereto.

The crosslinking mediator and the carbodiimide-based compound may form crosslinks in two ways. Aspartic acid and glutamic acid, amino acids having a carboxyl group on the surface of protein of hair, skin or fiber, react with the carbodiimide compound first to form a reactive ester, followed by reaction with a crosslinking mediator having an amine moiety to form a covalent bond. Alternatively, a crosslinking mediator having a carboxyl group may be first reacted with a carbodiimide-based compound to form a reactive ester, followed by reaction with an amino acid of a living body having an amine moiety to form a covalent bond.

In a preferred embodiment, the crosslinking mediator having a carboxyl group is made in the form of a reactive ester crosslinking mediator with direct bioreactivity or an amino acid (ex, aspartic acid, glutamic acid) present in excess in the hair (17.5-21.9%). Carbodiimide-based compounds that can be targeted by crosslinking mediators comprising amine groups by reactive esterification can be used to form reactive ester forms (reactive hair strengthening components) to increase the reaction efficiency, thereby significantly increasing the effect. have.

In addition, the crosslinking mediator of the present invention may be targeted to other amino acids such as carbodiimide, imidoester, arylazide, diazirine, hydroxymethyl phosphine, pentafluorophenylester, pyridyl disulfide, sulfo- Functional groups such as hydroxysuccinimide esters, alkoxy amines, hydrazides, haloacetyls, and azides may be further included in the molecule, in which case more bonds can be formed, more effectively preventing the loss of internal components. can do.

In a more specific example, the composition may be a polymer-type carbodiimide compound or a 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide on the surface of the crosslinking mediator having a carboxyl group or the protein surface of the hair / skin / fiber. Carbodiimide-based compounds such as hydrochloric acid (1-ethyl-3- (3-dimethylaminopropyl) carbodiimide.HCl) are first reacted to form a reactive ester, and a crosslinking mediator having an amine back to the formed reactive ester functional group. By reacting or reacting with an amine on the hair / skin / fiber surface, the bond between components can be formed to obtain an excellent hair / skin / fiber reinforcing effect.

The reaction may preferably be carried out at conditions of pH 2 to pH 10, or may be reacted at pH 3 to 9, or to react on an acidic to weakly acidic aqueous solution having a pH of about 4 to 5 having the best reaction efficiency. Can be. The reaction can be completed within 1 to 30 minutes.

The composition of the present invention may include a crosslinking mediator having a carboxyl group or an amine group in an amount of 0.0001 to 10% by weight in the total composition, and a carbodiimide compound in an amount of 0.0001 to 10% by weight in the total composition, or The crosslinking mediator having a carboxyl group or an amine group may be included in an amount of 0.01 to 10% by weight in the total composition, and the carbodiimide compound may be included in an amount of 0.01 to 10% by weight in the total composition.

Compositions of the present invention include polar oils and / or cationic cellulose polymers. The composition of the present invention can prevent the loss of components in hair, skin or fibers through the polar oil and / or cationic cellulose polymer, and in particular, effectively prevents the loss of internal components with amphipathic or low hydrophobicity. can do. This means that during cleaning, the polar oil or cationic cellulose polymer binds to the surfactant instead of the internal component to prevent loss of the internal component and increases the interfacial tension of the hair, skin or fiber surface by increasing the charge density of the hair, skin or fiber. This lowers the internal component contact angle, thereby preventing the hydrophobic weak or amphipathic internal components from being lost by the surfactant when exposed to the surface of the hair, skin or fibers.

In particular, the composition comprising the crosslinking mediator component of the present invention and the carbodiimide-based compound effectively suppresses the loss of the hydrophobic component, but has a relatively low hydrophobicity or a relatively weak effect of preventing the loss of the amphipathic component. As it was confirmed, the composition of the present invention may further include a polar oil and / or a cationic cellulose polymer together with the crosslinking mediator component and the carbodiimide-based compound. In this case, the loss due to the penetration of the surfactant and the diffusion of the internal components can be effectively prevented. In particular, in the case of further comprising a polar oil and / or a cationic cellulose polymer together with a crosslinking mediator component and a carbodiimide-based compound, the effect of preventing the loss of internal components is significantly better than that of each component alone. This can be confirmed through an embodiment of the invention.

In the present invention, the oil may be transported to the hair, skin or fibers by coacervate formed when diluted in micelle or water of the cosmetic composition. Anything that can adsorb / permeate hair, skin or fibers can be included in the present invention without limitation, and preferably polar oil. Polar oil in the composition of the present invention is 0.0001 to 10% by weight; Alternatively 0.01 to 10 wt%; Or 0.1 to 5% by weight.

In the present invention, the polarity may be evaluated according to the polarity commonly used in the art, and may be included in the present invention as long as it is classified as a polar oil by a conventional evaluation method in the art. More specifically, it may be evaluated according to the polarity evaluation method of Evonik, which presents a value inversely proportional to the interfacial tension value in water and oil as an oil polarity classification criterion. More specifically, the interfacial tension of the oil is a drop shape analyzer (Drop shape analyzer, KRUESS, Germany) to form an oil drop in the water tank, through the image analysis, measuring the length and diameter of the drop and the angle formed, and then It can be calculated by the Young-Laplace equation of the general formula (1).

[Formula 1]

In the present invention, the polar oil may preferably be an oil having an interfacial tension of 150 mN / m or less based on an interfacial tension value of 80 to 180mM / m measured by the above method.

The polar oil may be a saturated and / or unsaturated, branched and / or unbranched alcohol of chain length of 3 to 30 carbon atoms and a saturated and / or unsaturated, branched and / or chain length of 3 to 30 carbon atoms. Or esters of aromatic carboxylic acids with saturated and / or unsaturated, branched and / or unbranched alcohols selected from the group of esters of unbranched alkancarboxylic acids, and of chain lengths of from 3 to 30 carbon atoms Can be selected from the group. These ester oils are isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate Latex, isononyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2-octyldodecyl palmitate, oleyl oleate, oleyl erucate, erucyl Oleate, erucil erucate, dicaprylyl carbonate (cethiol CC), cocoglycerides (myritol 331), butylene glycol dicaprylate / dicaprate, dibutyl adipate and the synthesis, semisynthesis, of these esters, It may be selected from the group consisting of natural mixtures (eg, jojoba oil) such as plants, animals, or minerals, more preferably, in the oil Standing the interfacial tension may be not more than 150 mN / m.

In an embodiment of the present invention, when a hair cleanser comprising TEGOSOFT APM (PPG3-myristyl ether) from Evonik as a polar oil is applied to the hair, the oil penetrates into the hair and thus has a low hydrophobic or amphiphilic internal component. It was confirmed that it can prevent the loss. Specifically, when the non-polar oil having an interfacial tension value exceeding 150 mN / m is used in the composition, the oil does not penetrate into the hair but remains on the surface and is washed by water during the washing process, thereby losing the lipid in the hair. Did not prevent. However, polar oil penetrates into the hair, and as low hydrophobic or amphiphilic lipids diffuse and move towards the surface of the hair, the polar oil moves together, binding the surfactant and the polar oil that is encountered in the cleaning process, thereby releasing the lipid out of the hair. Elution and loss can be prevented.

The cationic cellulose polymer may be a nitrogen content of 1.5% by weight or more based on the total weight of the polymer. Preferably the nitrogen content may be 1.5% to 3.5% by weight, or 1.8 to 3.2% by weight, or 2.0 to 3.0% by weight relative to the total weight of the polymer. When the content of nitrogen in the polymer is 1.5% by weight or more, it is possible to more effectively prevent the loss of hair, skin or fiber components.

The cationic cellulose polymer is ethylene oxide (EO) or OH bonded to carbon 2 and 3 of the glucose unit in the cellulose backbone is hydrogen bondable, and the OH site bonded to carbon 6 is hydrogen through a linker. Cationic quaternary ammonium, which is not capable of binding, may be introduced.

The cationic cellulose polymer may preferably be a quaternized ammonium salt comprising hydroxy ethyl cellulose and trimethylamine.

The cationic cellulose polymer may be a polymer substituted with ethylene oxide (EO) at the α and β positions in the glucose ring.

The cationic cellulose polymer of the present invention can be synthesized and used according to the method described in the present invention, and a commercially available cellulose polymer can be used. Commercially available cellulose polymer may be, for example, a total nitrogen content of at least 1.5% by weight in polyquaternium-10.

In one embodiment of the present invention, when the cationic cellulose polymer containing nitrogen at 1.7 or 2.8% by weight, it was confirmed that the amphiphilic internal component or the relatively low hydrophobic internal component was prevented during the cleaning process. Amphiphilic internal components or relatively low hydrophobic internal components, as confirmed in Test Example 1 of the present invention, are eluted by diffusion over time in the washing process, and meet with anionic surfactants on the surface of skin, hair or fibers. It is confirmed that the cationic cellulose polymer of the present invention is bound by contact with anionic surfactants on the surface of the skin, hair or fibers instead of lipids, thereby preventing the loss of lipids.

More specifically, the cationic cellulose polymer may be a quaternary ammonium salt represented by the following formula (1).

[Formula 1]

In Formula 1, α and β may be ethylene oxide (EO) or OH, and any one of α and β may be ethylene oxide (EO).

x is 1 to 10, preferably 1 to 5, more preferably 1 to 3.

n is 1 to 10, preferably 1 to 5, more preferably 1 to 3.

y is 0 to 1, and when n is 1, y may be 0.3 to 0.7, preferably 0.4 to 0.6, more preferably 0.45 to 0.55.

The cationic cellulose polymer of the present invention may have a molecular weight of 300,000 to 2.9 million, or 600,000 to 2.5 million, or 70 to 1.5 million.

Cationic cellulose polymers of the present invention can be synthesized by synthetic methods commonly used in the art.

As a specific example, a quaternary ammonium salt obtained by quaternization of hydroxy ethyl cellulose with chlorohydroxypropyl trimethylamine may be prepared. Specifically, sodium hydroxide and urea are contained in a weight ratio of 7 to 9: 10 to 12: 75 to 85 (sodium hydroxide: urea: water) with respect to water as a solvent, and then, hydroxyethyl cellulose is contained in a concentration of 1 to 3% by weight. It can be prepared by dissolving, and then further containing a quaternary ammonium compound. More specifically, after containing sodium hydroxide and urea in a weight ratio of 7.5: 11: 81.5 (sodium hydroxide: urea: water) with respect to water as a solvent, it can be prepared by dissolving hydroxy ethyl cellulose at a concentration of 2% by weight. . The solvent of the composition helps to improve the solubility and stability of hydroxyethyl cellulose to help improve the uniformity of the modification in the reaction process [Bi Xiong, Dissolution of cellulose in aqueous NaOH / urea solution: role of urea, Cellulose (2014) 21: 1183-1192. Thereafter, the quaternary ammonium compound may be further added at an appropriate concentration (1 mole or more moles relative to the glucose monomer of cellulose) to be modified while the reaction proceeds according to room temperature or warming conditions, thereby obtaining a cationic cellulose polymer of the present invention. have.

The position having a modifiable hydroxyl group in the glucose ring of the cationic cellulose polymer may be C ₂ , C ₃ and / or C ₆ . Of these, the C ₆ primary alcohols generally have good position selectivity for the reforming reaction because they have minimized steric hindrance. In contrast, the difference in preference reaction between C ₂ and C ₃ may vary depending on conditions such as solvent system [Mitsuru Abe, Regioselectivity in Acetylation of Cellulose in Ionic Liquids, Materials Science inc. Nanomaterials & Polymers (2016) 1: 2474-2478.

In the case of adding EO to the α and β positions in the glucose ring, gas phase polymerization using epoxide may be performed, the reactant in the chamber may be injected, and then heated and pressurized to proceed with EO addition. In the case of alkylation, the reaction may be carried out using a reactant having a halohydrin, an aldehyde or an epoxide terminal functional group so that a desired alkyl group can be added.

In one embodiment of the present invention was prepared by adding EO to the α or β position in the glucose of the cationic cellulose polymer substituted with trimethyl amine in the formula (1).

In addition, in order to increase the nitrogen content of the quaternary ammonium salt in the cationic polymer of the present invention, the addition reaction process of the quaternary ammonium compound of Reaction 1 described above is repeated while varying the amount of trimethylamine and adjusting the temperature conditions. As a result, the amount of cationization can be controlled by adjusting the nitrogen content. This can be confirmed through elemental content analysis.

The composition of the present invention may comprise cationic cellulose polymer and / or polar oil in 0.001 to 10% by weight, or 0.01 to 10% by weight, or 0.1 to 5% by weight in the total composition.

Preferably, the composition of the present invention comprises a crosslinking mediator having a carboxyl group or an amine group and a carbodiimide-based compound; Cationic cellulose polymers; And polar oils. In the case of the composition it was confirmed experimentally that the anti-loss effect of the components in the hair, skin or fibers.

Specifically, in one embodiment of the present invention, in the case of a composition containing all three components, it was confirmed that the loss of both hydrophobic lipids, low hydrophobic lipids and amphiphilic lipids is significantly prevented, which is cationic cellulose polymer or polar It was experimentally confirmed that the crosslinking mediator having an oil and a carboxyl group / amine group and a carbodiimide-based compound had more significant effects.

The composition of the present invention comprises 0.0001 to 10% by weight of the cationic cellulose polymer in the total composition; 0.0001 to 10 wt% polar oil; And a sum of the crosslinking mediator component having a carboxyl group or an amine group and the carbodiimide-based compound in an amount of 0.0001 to 10 wt%, and each of the components in an amount of 0.01 to 10 wt%. In the case of a composition containing all of the above components, the effect of preventing the loss of internal components in hair, skin or fibers is very excellent.

The composition of the present invention may further comprise one or more selected from the group consisting of cationic polymer, surfactant and oil.

Cationic polymer of the present invention means a polymer additionally included in addition to the cationic cellulose polymer. For example, it may be any one or more selected from the group consisting of cellulose-based polymers, guar-based polymers, and synthetic polymers. The cellulose-based polymer may be JR125, JR400, JR30M, POLYQUAT-3000KC, LR-400R-LO, LR30M, Ucare LK, Catinal HC100, Catinal HC200, or the like. In another specific example, the guar gum polymer, the synthetic polymer may include polyquaternium-22, polyquaternium-47, polyquaternium-53, dimethyldiallylammonium chloride polymer, acrylamide-dimethyldiallylammonium chloride copolymer, Polyvinylpyrrolidone (PVP) -dimethylaminoethylmethacrylate copolymer, acrylic acid-dimethyldiallylammonium chloride copolymer, acrylamide-dimethylaminoethylmethacrylate methyl chloride copolymer and trimethylaminoethylmethacrylate polymer One or more selected from the group consisting of, but is not limited thereto. The composition of the present invention may not include a cationic surfactant when the cationic polymer is included. In this case, it is possible to provide a composition having no skin irritation by the conventional cationic surfactant used to give the hair, skin or fiber a softening effect.

As the 'surfactant', any one or more selected from the group consisting of anionic surfactants, amphoteric surfactants and nonionic surfactants may be used in the composition of the present invention. The surfactants basically have a detergency effect as used in conventional compositions. The surfactant of the present invention may be used to form micelles with the C _10-20 alkyl group of the aforementioned alkyl cellulose.

As anionic surfactant, sodium lauryl sulfate, sodium laures sulfate, polyoxyethylene sodium lauryl sulfate, ammonium lauryl sulfosuccinate, ammonium myresulfate, disodium laureth sulfosuccinate, disodium C12-C14 pares-2 Sulfosuccinate, or mixtures thereof and the like can be used. In addition, the amphoteric surfactant may be any one or more selected from the group consisting of betaine, cocomidopropyl betaine, amido propyl betaine, and coco amppocarboxy glycinate. In addition, the nonionic surfactant may be used any one or more selected from the group consisting of caprylyl / caprylglucoside, cocoglucoside, lauramiddiei, cocaramidediei, cocaramidemethylA and glyceryl monostearate have.

The anionic surfactant may be included in 1 to 30% by weight, specifically 3 to 20% by weight relative to the total weight of the composition. The amphoteric surfactant may be included in an amount of 0.1 to 20% by weight, specifically 2 to 15% by weight, based on the total weight of the composition.

Oils may additionally be used in the compositions of the present invention. Non-limiting examples of such oils are components commonly referred to as silicones such as water-insoluble nonvolatile dimethicone, cyclomethicone, aminated silicone, trimethylsilylamodimethicone or vinyl silicone, and derivatives thereof, vegetable oils, vegetable oils and fats. , Animal oils, animal fats and oils, hydrocarbon oils or synthetic ester oils and the like can be used. Hydrocarbon oils may include liquid paraffin, isoparaffin, or hydrogenated polydecene, and the like, and ester oils include isopropyl myristin, isopropyl palmitate, isostearic acid isostearyl or C12-15 alkyl benzoate, triethylhexanoin, squalane , Palm oil, Olea Europaea oil, PPG-3 Caprylyl ether, Capric / caprylic triglyceride, Isostearyl isostearate Isostearate, Cocos Nucifera, Polyglyceryl-6 octacaprylate, Hydrogenated polydecene, Jojoba seed oil, DI-C 12-13 alkyl marate may be used, but is not limited thereto.

In addition, the cosmetic composition for hair or fiber treatment of the present invention can be used as a shampoo. In this case, in order to further enhance the conditioning effect, it may further include an additional adjuvant used in the art within the scope of not impairing the object of the present invention. For example, fatty substances, organic solvents, solubilizers, thickeners, gelling agents, emollients, antioxidants, suspending agents, stabilizers, blowing agents, fragrances, surfactants, water, ionic or non- conventionally used in hair compositions It may include any one or more selected from the group comprising ionic emulsifiers, fillers, metal ion sequestrants, preservatives, vitamins, blockers, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic active agents and the like.

In addition, the compositions of the present invention may additionally include additives that provide beneficial properties to the human body. For example, washing, volume, trimming, protection, blocking, moisturizing, dyeing, coloring, bleaching, limiting, deodorization, antiseptic, refreshing, depilation, hair growth, anti dandruff, anti hair loss, wool, anti-inflammatory, fragrance, aroma, whitening, Anti-aging, anti-wrinkle, convergence, relaxation, contraction, sebum control, exfoliation, sterilization, anti-inflammatory, yangyang, deodorant, antihistamine, anti seborrheic, blood circulation, sun protection or skin metabolism It may further include additives.

In addition to this, the composition of the present invention may further contain preservatives, thickeners, viscosity regulators, pH regulators, fragrances, dyes or conditioning agents, etc., which can be conventionally used as a component of the hair composition, these are easily purchased commercially Can be used. Examples of preservatives include mixtures of benzoic acid and salts, methyl paraoxybenzoate, methylchloroisothiazolinone or methylisothiazolinone (trade name: Kathon CG, The Dow Chemical Company). As the thickener and the viscosity modifier, hydroxypropylmethylcellulose, hydroxymethylcellulose, sodium chloride, ammonium chloride, propylene glycol, hexylene glycol, sodium xylene sulfone, or ammonium xylene sulfonate may be used. As the pH adjusting agent, citric acid, sodium hydroxide or triethanolamine and the like can be used. As the dye, a water-soluble tar dye may be used. And as a conditioning agent, animal and vegetable extracts, proteins and protein variants, fatty acids (Fatty Acid) and the like can be used.

The term expressing the effect in the present invention, "bending strength" refers to the degree to which it is hard to bend well, and is slightly different from the stiffness of the surface simply by increasing the frictional force. As a measure to measure the bending strength, 'bending strength' is used to mean the degree of hardening due to the lack of bending when the longitudinal axis is bent. Higher bending strength means that the strength of the hair is increased. In the specific test example of the present invention, after treating and rinsing the shampoo composition to the hair and evaluating using a bending strength evaluator, it was confirmed that the bending strength of the hair treated with the composition of the present invention was higher than that of the untreated hair.

The composition of the present invention can effectively prevent the loss of internal components in the hair, skin or fibers during the cleaning process, in this aspect the present invention provides a composition for treating hair, skin or fibers that can prevent the loss of internal components do.

The hair, skin or fiber treatment composition may be for preventing the loss of lipids in the hair, skin or fibers.

The composition of the present invention may be treated alone or for the purpose described above, or may be treated in a form contained in a detergent, cosmetic or external preparation.

In this aspect, the present invention provides a cleaning composition comprising the composition for preventing hair, skin or fiber components. The cleaning composition is meant to include both a composition for cleaning the human body, including skin and hair, and a composition for washing fibers or articles including clothing, tableware, and the like. The cleaning composition may be commercialized as a cleaning agent, and as an example of the cleaning agent, a cleansing foam, cleansing lotion, cleansing cream, body lotion and body cleanser antiseptic cleaner, shower foam, cleaning tissue, detergent soap, hand wash, detergent, conditioning agent, It may be a face wash or a shampoo, but is not limited thereto.

The present invention also provides a cosmetic composition comprising the composition for preventing hair, skin or fiber components. The cosmetic composition is a cosmetically acceptable carrier, diluent, adjuvant, colorant, stabilizer, flavoring agent, surfactant, oil, moisturizer, alcohol, thickener, antioxidant, pH adjuster, sunscreen, etc. to facilitate use and handling. It may further contain, and when used as an external skin composition, it can be used in any formulation that can be applied to the skin, such as liquid, oil, cream, ointment, stick, pack, pasta, powder. In addition, these may be included alone or in combination of two or more.

When formulating the cosmetic composition into a cosmetic may include a known dermatologically acceptable excipient that acts as a carrier for the active ingredient, specifically International cosmetic ingredient dictionary, 6th ed., The cosmetic, Toiletry and Fragrance Association , Inc., Washington, 1995, incorporated herein by this reference. Such documents are incorporated as part of this specification.

The compositions of the present invention add carriers, diluents, adjuvants, colorants, stabilizers, flavoring agents, surfactants, oils, humectants, alcohols, thickeners, antioxidants, pH adjusting agents, sunscreens, etc., which are acceptable for ease of use and handling. It may contain. Specific examples may use those conventionally used in the art.

In the present invention, the composition may be in the form of a general emulsion formulation or solubilized formulation. It may be in the form of a powder, emulsion, suspension, oil, spray, ointment, grease ointment, cream paste, gel, foam or liquid, and may be solid or semisolid by drying or concentration or the like. As a specific example, the composition of the present invention may be any one formulation selected from the group comprising shampoo, hair conditioner, hair lotion, hair essence, hair gel, hair pack, patch and spray.

When the composition of the present invention is commercialized for dermatological treatment or improvement, it may include each component in a higher concentration than when commercialized into cosmetics that are routinely applied to the skin. Even in the case of cosmetics, in the case of a wash-off type cosmetic such as a make-up remover, a detergent, etc., in which an active ingredient stays on the skin within a short period of time, it may include a relatively high concentration of each component. On the other hand, in the case of a leave-on type cosmetic such as a lotion, an emulsion, a cream, an essence, etc., in which the active ingredient stays on the skin for a long time, it may include lower concentrations of each component than the wash-off type cosmetics. .

Hereinafter, in order to help the understanding of the present invention will be described in detail with examples. However, the embodiment according to the present invention may be modified in various other forms, and the scope of the present invention should not be construed as being limited to the following examples. The embodiments of the present invention are provided to more completely explain the present invention to those skilled in the art.

[Production example]

In the general polymer used in the embodiment of the present invention, cellulose having a quaternary ammonium was purchased as a raw material synthesized from Dow Chemical, or a cationic polymer was synthesized according to the following preparation example and used as a raw material.

1. Preparation of Cationic Polymer

In the polymerization process, the molecular weight was controlled by changing the content of ethyl cellulose, and the nitrogen content was controlled by varying the amount of trimethylamine used. A quaternized ammonium salt was obtained by quaternization of hydroxy ethyl cellulose with chlorohydroxypropyl trimethylamine.

Specifically, sodium hydroxide and urea were contained in a weight ratio of 7.5: 11: 81.5 with respect to water as a solvent, and then hydroxyethyl cellulose was dissolved at a concentration of 2 wt%.

Thereafter, the quaternary ammonium compound is further contained in an appropriate excess concentration (3, 6, 9 times the number of moles of glucose rings of cellulose), and the reaction is carried out to be modified according to the temperature (25, 45, 60 ° C.) conditions. A quaternary cationic cellulose polymer of Formula 1 was prepared. Also, referring to the reference (WO 2016085099 A1), EO addition or alkylation was performed to prepare a structure including an alkyl group. Specifically, gas phase polymerization was performed using epoxide to add ethylene oxide (EO) at the α or β position in the glucose ring of the cationic cellulose polymer of Chemical Formula 1, and after spraying the reactant in the chamber, The reaction was carried out by applying pressure to add EO. In the case of alkylation, the reaction was carried out using a reactant having a halohydrin, an aldehyde or an epoxide terminal functional group to add a desired alkyl group, and the OH group at the α or β position in the glucose ring was substituted with alkyl. .

A cationic cellulose polymer having a molecular weight of 800,000, wherein α is EO, β is OH, and a nitrogen content (% by weight) of 2.7% by the above method; cationic cellulose polymers having a molecular weight of 800,000, wherein α is EO (bivalent or higher), β is OH, and nitrogen content (% by weight); cationic cellulose polymers having a molecular weight of 800,000, wherein α is EO (bivalent or higher), β is EO (monovalent or higher), and nitrogen content (% by weight); cationic cellulose polymers having a molecular weight of 1.8 million, wherein α is EO (bivalent or higher), β is OH, and nitrogen content (% by weight); And a cationic cellulose polymer having a molecular weight of 2.5 million, wherein α is EO (bivalent or higher), β is OH, and a nitrogen content (% by weight) of 2.7% was synthesized and used for the following test. In addition, under the same conditions as above, a cationic cellulose polymer having a nitrogen content of 1.7 wt% was also synthesized and used in subsequent experiments.

2. Preparation of Cleaning Liquid Composition

To prepare a shampoo cleaning liquid composition in a conventional manner according to the prescription shown in Table 1. Polymers and / or oils included in the cleaning solution were prepared according to the following Examples or Comparative Examples. Specifically, after adding the polymer, the surfactant was added several times to dissolve, followed by neutralization of pH by adding EDTA.4Na and hydrous citric acid. Other ingredients added preservatives, fragrances, dispersants, viscosity regulators and pH regulators.

Ingredient weight ( % ) Polymers and / or oils 1.0 Sodium Lauryl Sulfate (SLS) 8 Cocamido propyl betaine 4.5 EDTA 4Na, function citric acid 0.1 Other ingredients 16 Purified water Balance (to 100)

Next, the conditioner was prepared as shown in Table 2.

Ingredient weight ( % ) Purified water 75 Glyceryl Stearate 0.1 Cetearyl Alcohol 5 Beentrimonium Chloride 2 Purified water Balance (to 100)

[Test Example]

Test Example 1 Lipid Quantitative Evaluation by GC / MS Spectrum

(1) Evaluation method

Shampoo 1g hair tress was treated with 1 mL of shampoo, rubbed and foamed for 45 seconds and rinsed with water for 4 minutes / second flowing for 2 minutes was repeated five times. Next, the hair was left for 1 day at 50% RH condition in a constant temperature and humidity room, and then crushed finely at 1 mm intervals. Quantitative / Qualitative analysis in / MS (Aglient 5977B GC / MSD) SIM mode.

For GC / MS, a mixture of chloroform and methanol in a ratio of 2: 1 to 5000 ppm was prepared by mixing the indicators. Internal solution was used as 50 ppm of tricosanoic acid. Ionization voltage was 70eV, 250 degrees, and HP-5ms UI column (30mX0.25mmX0.25㎛) was used. The temperature was raised from 80 ° C. to 320 ° C. at 5 ° C. per minute. The population n = 10 in all experiments.

(2) Evaluation according to the kind of polymer

Experiment 1 to 4

In the shampoo composition shown in Table 1 above, LR30M was used as a polymer, and the hair was treated 10 times with shampoo, and then the quantitative value obtained by GC / MS analysis was 100% of the GC / MS quantitative value of unshampooed hair. By calculating the relative value as a reference, the analysis results shown in Table 3 were obtained. Group A consists of myristyl acid (C ₁₄ ), palmitic acid (C ₁₆ ), stearic acid (C ₁₈ ), oleic acid (C _{18 = 1} ), cholesterol (Cholesterol) Group B is a hydrophobic lipid that contains C ₁₄ -C ₁₄ , C ₁₄ -C ₁₆ , C ₁₆ -C ₁₆ , C ₁₈ -C ₁₆ among squalene and wax esters. it means. The results in Table 3 refer to the content of each lipid, which means the relative value (%) relative to the control (GC / MS quantitative value of unshampooed hair).

Type of lipid Content in the short-term treatment % ) Content for long-term treatment % ) Experiment 1 Experiment 2 Experiment 3 Experiment 4 Lipid A group C ₁₄ 75 ± 1 68 ± 2 65 ± 3 59 ± 1 C ₁₆ 72 ± 1 66 ± 1 63 ± 2 57 ± 1 C ₁₈ 70 ± 1 68 ± 1 63 ± 2 59 ± 1 C _{18 = 1} 75 ± 1 73 ± 1 62 ± 3 59 ± 1 Cholesterol 76 ± 1 74 ± 1 73 ± 2 72 ± 1 Lipid B group Squalene 57 ± 2 82 ± 1 43 ± 1 75 ± 1 C ₁₄ -C ₁₆ 61 ± 2 76 ± 9 45 ± 3 45 ± 3 C ₁₆ -C ₁₆ 55 ± 1 58 ± 6 42 ± 2 36 ± 1 C ₁₈ -C ₁₆ 55 ± 1 71 ± 1 48 ± 6 46 ± 6 C ₁₄ -C ₁₄ 57 ± 3 77 ± 6 48 ± 4 67 ± 5

Specifically, Experiment 1 is to use a 10% dilution of shampoo in the composition of Table 1, give a certain physical pressure and wash the hair 10 times by hand. Rinsing was bubbled with shampoo solution for 50 seconds and washed for 2 minutes. Since the actual shampoo liquid was in contact with the hair for 10 minutes, Experiment 2 was performed while stirring with a shaker (Jeio Tech, SI-900R, Korea) for 10 minutes under the same concentration conditions. Experiment 2 differs from Experiment 1 in that cleaning is performed without physical pressure. In Experiment 3, the treatment of Experiment 1 was performed for 30 minutes, and Experiment 4 was performed by increasing the treatment time by 30 minutes under the same conditions as in Experiment 2.

As a result, as shown in Table 3 and Figure 2, the lipid loss pattern of Experiment 1 and Experiment 3, which induced the penetration of the surfactant by applying a physical pressure in the short-term and long-term treatment, and Experiment 2 stirred without physical pressure In Experiment 4 and 4, we observed that the loss patterns of lipids were different.

In experiments 1 and 3, the hydrophobic lipids of group B were more lost than those of relatively low hydrophobic or amphiphilic group A. In experiments 2 and 4, amphiphilic or relatively low (particularly group B) It was confirmed that more hydrophobic lipids of group A than hydrophobic groups (lower than lipids) were lost.

Although experiments 1 and 3 have the same concentration of shampoo as compared to experiments 2 and 4, in experiments 1 and 3, the aggregation of coacervation occurs, so that a high concentration of shampoo solution, Anionic surfactants come into contact with the hair. And by applying friction and physical pressure to the hair by hand, the surfactant can more easily penetrate into the hair, and the penetrating surfactant is easily combined with the hydrophobic component inside the hair. As previously reported, the penetration of molecules into the hair has been reported that when the ratio of amphoteric and anionic surfactants is 2: 1, spherical micelles, rather than cylinders, are formed at 150 mM or less (Langmuir, 20, (2004) 571), it is not known whether hair micelles penetrate directly into the hair or if surfactant single molecules penetrate and re-form micelles, but the surfactant micelles are 6.0 ± 0.6 nm with Cryo TEM. Imaging at size proved to penetrate inside the hair (Langmuir, 4 (1988) 1066). For reference, the largest observed micelle size was 4.8 nm (Langmuir, 4 (1988) 1066), and imaging confirmed the presence of micelles in the outer part of the hair using the EDX mapping method (Int. J. Cos. Sci. 26 (2004) 61). Therefore, according to the conventional research results, assuming that anionic surfactant penetrates into the hair and forms micelles during the washing process, hydrophobic lipids of group B are collected by micelles penetrating into the hair and thus outside the hair. It was expected to disappear by exiting.

As in the examples of Experiments 2 and 4, group A shows a result of gradually disappearing and disappearing with time at relatively low concentration. In the washing process, since the lipids of group A inside the hair are not completely hydrophobic, there is a high possibility that the whole cannot be collected in micelles formed by the surfactant. Therefore, the lipids of the group A are not lost by the surfactants inside, but the release of the lipids inside the hair to the outside (J. Cosmet.sci., 49, (1998) 223), that is, the diffusion of lipids Is eluted out by. The group A was found to be displaced to the outside of the hair by diffusion and then to be lost by meeting with the anionic surfactant existing outside the hair.

Test Example 2 Hair Surface Treatment

Since it was confirmed that the lipid of group A was lost by the anionic surfactant in the outer layer of the hair, in order to suppress the diffusion of the lipid of the group A to reduce the probability of contacting the lipid with the lipid, according to the prescription of Table 4, the table The shampoo composition of 1 and the conditioner composition of Table 2 were prepared and treated to the hair. The conditioner was also cleaned once a total of 10 treatments after shampooing and after each cleaning cycle it was completely dried with a dryer to promote diffusion with heat.

Various sebum and grease remain on the hair, which was washed once with sodium laurate sulfate (SLES) as Comparative Example 1. As reported in the previous study, light washing showed that lipids with 3 nm depth of hair remained (J, Cosmet Sci. 61 (6) (2010), 467-77). The assumption was made that lipids did not elute.

Comparative Example 2 used Ucare LK of the cationic cellulose polymer PQ10 having a nitrogen content of 0.5% by weight in the formulation of Table 1, Comparative Example 3 was 1.0% nitrogen by weight in the formulation of Table 1 It was used as LR30M of phosphorus cationic cellulose polymer PQ10.

In Comparative Examples 4 and 5, Abil WAX 9840 and WAX9801 manufactured by Evonik Co., Ltd. were used to have a water / oil interface tension of 120 mN / m or more in the formulation of Table 1, respectively.

In Examples 1 and 2, cationic cellulose polymers (α: EO (bivalent or higher), β: OH, and molecular weight of 800,000) having a nitrogen content of 1.7% and 2.8% by weight in the formulation of Table 1 were prepared. According to the method of synthesis were used respectively. In Examples 3 and 4, the water / oil interfacial tension is 100 mN / m or less, and TEGOSOFT APM and TEGOSOFT E are selectively included and treated with a stirred shampoo.

sample Comparative Example 1 Comparative Example 2 Comparative Example 3 Example 1 Example 2 Comparative Example 4 Comparative Example 5 Example 3 Example 4 N content (wt%) in polymer - 0.5 1.0 1.7 2.8 1.0 1.0 1.0 1.0 Polar oil (mM / m) - - - - - 160 120 100 90

Geology Comparative Example 1 Comparative Example 2 Comparative Example 3 Example 1 Example 2 Comparative Example 4 Comparative Example 5 Example 3 Example 4 Total content of group A 100% 36% 36% 52% 54% 36% 37% 47% 48% Total content of group B 100% 38% 38% 39% 40% 37% 37% 37% 37%

Table 5 averages the content of the lipids of group A and the lipids of group B (the remaining amount in the hair after washing) with the percentage of the control group (Comparative Example 1). According to the results of Examples 1 and 2 of Table 5, the shampoo treatment through cationic polymer can prevent the loss of lipids of group A, while the lipids of group B are not protected. . Similarly in Examples 3 and 4 it can be seen that the lipids of Group A are better protected when using oils with interfacial tension of 100 mN / m or less. Comparing Example 1/2 and Example 3/4, the polymer containing has a better prevention of lipid loss than the case containing the polar oil. It combines with other oils and polymers instead of lipids, because cationic cellulose polymers are adsorbed on the surface of the hair and combined with surfactants, which is difficult to elute due to the properties of the polymer, so that the film film is not lost from the hair. In addition, polar oils or high nitrogen content polymers increase the charge density on the surface of the hair, resulting in lower interfacial tension on the surface of the hair, resulting in a lower contact angle of the lipids, resulting in contact with the hydrophobic group A lipids when exposed to the surface. The loss by the surfactant is prevented.

Test Example 3 Group B Lipid Defense: Hair Internal Treatment

Polycarbodiimide (PCI) was used to crosslink together using polylysine or polyamine or soy protein for amine binding to hair as a crosslinking media component ( Table 6). In accordance with the formulation of Table 1, 400 rpm by adding a cross-linking media component of Table 6 and a composition containing polycarbodiimide to the composition of the shampoo prepared by containing a PQ10 polymer (LR30M) having a nitrogen content of 1.0% as a polymer The mixture was stirred at room temperature for 10 minutes. Then, the content of lipids in the hair was measured in the same manner as in Test Example 2.

Relative value (%) of each lipid content of the hair treated with the crosslinking media component of Table 6 and PCI-added shampoo based on the lipid content value in the hair washed once with sodium laurate sulfate (SLES) of Comparative Example 1 Calculated as shown in Table 7. In order to easily compare the behavior characteristics according to lipids, the average value of five lipid components of myristyl acid, palmitic acid, stearic acid, oleic acid, and cholesterol is expressed as the content of group A lipid, and squalene, wax ester C _14- The average content of four lipid components of C ₁₄ , C ₁₄ -C ₁₆ , C ₁₆ -C ₁₆ , and C ₁₈ -C ₁₆ is expressed as the content of Group B lipids.

sample Example 5 Example 6 Example 7 Polylysine 0.5% - - Polyamine - 0.5% - Soy protein (WS-SP) - - 0.5% PCI 0.5% 0.5% 0.5%

Lipid content Example 5 Example 6 Example 7 A group lipid 36% 36% 37% B group lipid 42% 47% 46%

As shown in Table 7, it was confirmed that the cross-linking is effective in the defense of Group B lipids. Crosslinking, however, had no protective effect on the loss of group A lipids. In other words, if the inside of the hair is densely packed by cross-linking, the surfactant micelle can penetrate into the hair to prevent the hydrophobic group B lipids from being collected and eluted, but the relatively less hydrophobic group A lipids are diffused to the outside and eluted. As it was confirmed that it is not prevented, the following experiment was conducted to provide a composition that can prevent the loss of both hydrophobic and amphiphilic / low hydrophobic components.

Test Example 4 Simultaneous Defense of Lipids of Groups A and B

In Tables 5 and 7, it was confirmed that lipid loss of group A and group B was prevented, and the shampoo and conditioner compositions of Tables 1 and 2 were prepared according to the prescription of Table 8 to confirm all lipid defense effects. Table 9 shows the values of GC / MS quantitation by washing the hair tress 10 times in the same manner as in Example 2. In Example 9, the nitrogen content was 1.7% by weight (α: EO (bivalent or higher), β: OH molecular weight 800,000), and Example 11 was the nitrogen content in 2.8% by weight (α: EO (divalent or higher), β: A cationic cellulose polymer of OH molecular weight 800,000) was synthesized and used in Examples 8 and 10 to 11 using TEGOSOFT APM (PPG-3 myristyl ether) from TEGOSOFT with an interfacial tension of 100 mM / m. The lipid content of Table 9 is averaged by the relative value (%) compared to the control (Comparative Example 1) value of Comparative Example 1. The content of each component in Table 8 means weight percent as the content of the component with respect to the total composition.

sample Example 8 Example 9 Example 10 Example 11 Polymer 0.5 0.5 - 0.34 oil 0.5 - 0.5 0.33 Polylysine & PCI - 0.5 0.5 0.33

Lipid content Example 8 Example 9 Example 10 Example 11 Lipid of group A 79% 76% 68% 99% Lipid of group B 46% 67% 64% 99%

Formulations containing cationic polymers and polar oils maintained the lipid content of group A very efficiently (Example 8), but the loss of lipids of group B was only slightly defended. Lipid loss prevention effect was slightly increased in Group B than Examples 1 to 4 of Table 5, which reduced friction and reduced the cuticle layer damage during the cleaning process, while the oil content reduced the penetration of surfactant micelle B It appears to have resulted in reducing the loss of group lipids.

In Examples 9 to 10 of Table 9, it can be seen that both the loss of lipids of Group A and Group B are protected. In particular, in Example 11, the surprising effect of the defense of most lipids can be seen. The synergistic effect of the defense is that the outer monomolecular oil or polymer cation coating reduces the number of micelles that attempt to penetrate into the interior as well as the outside, while tightly bound cross-linking when polar oil penetrates into the interior as well as the surface. By interfering with the flow of lipids that diffuse inside with the binding, it can be interpreted that the lipids are almost completely protected during the cleaning process.

Test Example 5. Evaluation of physical properties by treating the composition of Example 11

(1) evaluation of bending strength of hair

In order to confirm the effect of defending the loss of lipids on the hair, the composition of Comparative Example 1 (experimental group assuming no internal lipids were eluted), 2 or Example 9, Example 10 and Example 11 In order to evaluate the strength of each treated hair, the strength was evaluated using a bending strength evaluator KES-FB2-S (KATO TECH, Japan). Higher bending strength means that the strength of the hair is increased.

Sample tresses were prepared by attaching 200-200 micrometers of hair thickness, shampooed, to 10 cm in size. This evaluation method was evaluated according to the manual recommended by KATO TECH. When evaluating the bending strength of the fiber tress, the evaluation method was measured according to the evaluation method adopted as a standard evaluation by the textile evaluation public institution.

Bending Strength Evaluation Results

The results evaluated by the fiber strength evaluation device are shown in Table 10 below.

sample Comparative Example 1 Comparative Example 2 Example 9 Example 10 Example 11 Bending Strength (Unit: gf cm) 0.576 0.466 0.513 0.489 0.573

As shown in Table 10, the bending strength was very low as in Comparative Example 2 after 10 washes, that is, it can be seen that the hair strength is greatly reduced when washing the hair 10 times. However, in Example 11, the hair strength was almost the same as before washing.

(2) hair sensory evaluation

Based on the results, shampoo was prepared and sensory evaluation was performed. The experiment was conducted on 15 men and women, and the stiffness effect of hair after shampoo was evaluated based on the following evaluation smoothness.

The strength was determined by the following items in the order in which the hair strength was felt (the opposite is stiff): (5: very flexible); (4: flexible); (3: normal); (2: stiff); (1: very stiff) Hairdressing and calmness were evaluated according to the following items according to the degree of visible hair on the upper head (oppositely busy): (5: very calm); (4: difference); (3: normal); (2: busth); (1: very booth)

The composition was prepared by prescribing the guar gum polymer L80KC, which is generally prescribed for commercially available bristle shampoos, as the polymers in Table 1, and the compositions were treated in Experiments # 1 and 2, and were treated in Experiment # 3 using the formulation of Example 11. It was.

The results are shown in Table 11 below as an average value.

Experiment Experiment # 1 Experiment # 2 Experiment # 3 Strong 3.6 3.8 4.6 Differential 2.4 2.5 4.8

As can be seen from the experiment # 3 of Table 11, it can be seen that the shampoo of the present invention significantly increases the strength compared to the conventional bristle shampoo. In addition, we observed the effect of hair being hair-set and calmed. In Experiment # 3, it was found that the hair was not observed by showing a tendency to stick to the hair regardless of whether the hair of the experimenter was curly, half-curly, or straight hair. From this, it can be seen that by adsorption according to the composition of the present invention, it is efficiently delivered to various types of human hair.

(3) evaluation of the surface friction of the hair

Subsequently, the shampoo having the polymer composition of the present invention was quantified through the evaluation of the device in order to evaluate the softening conditioning effect and the feeling of use.

Experiment method

In Comparative Examples 1 and 2 and LG Household & Health Care's bristle shampoo and the composition of Example 11 were added to the Beaux hair tress 10% by weight relative to the weight of the hair, foamed for 15 seconds, rubbed for 20 seconds, and then After 15 seconds of rinsing under running tap water, the hair was washed with a towel to remove moisture, and then the frictional force was evaluated using a MTT 175 Miniature Tensile Tester (DiaSTRONG, GB).

The shampooed hair was rinsed for 2 minutes, then dried for 2 minutes with a dryer, maintained at 25 ° C. in a constant temperature and humidity chamber at 50% humidity for one day, and the moisture inside the hair was made constant, and then the frictional force was measured in the same temperature and humidity chamber. At this time, the hair tress was calculated by dividing by the friction force value (reference value) after washing with anionic surfactant sodium lauryl sulfate, and is shown in Table 12 below. In this case, the higher the friction% value, the smoother it is.

result

Experiment Experiment # 4
(Comparative Example 1) Experiment # 5
(Comparative Example 2) Experiment # 6
(Brissam sampu) Experiment # 7
Example 11 When rinsing -4% 55% 37% 56% After drying -6% 21% 26% 29%

In view of the results measured in Table 12, the shampoo having the polymer composition of the present invention has been shown to significantly reduce the friction force to promote a smooth conditioning effect. In particular, in the case of commercial bristle shampoo as shown in Experiment # 6, it can be seen that the smoothness effect is reduced. In other words, as can be seen in combination with the above embodiments, the polymer composition prepared in the present invention, when applied to the conditioning agent, prevents the loss of lipids, thereby strengthening the bending strength and reducing the flexibility. It has been found to be a component of an excellent hair conditioning cosmetic composition that gives smoothness.

(4) tensile strength

Four hairdressers (length 12 cm, weight 3 g) made of damaged hair were prepared by bleaching twice in total, and tensile strength (unit cN, 1gf = 0.98 cN) for 100 hairs in each hairtress was prepared. ) Was calculated and the average value was calculated as the reference value. At this time, the tensile strength measuring device of DIASTRON company was used for the tensile strength measurement.

Subsequently, hair tresses were respectively dipped in the composition according to Experiments # 4 to 7 of Table 12 for 10 seconds except for Experiment # 4, and then washed in running water for 30 seconds. Then, the hair was dried for 24 hours at room temperature (about 25 ℃). After measuring the tensile strength (cN) for 100 hairs in each hair tress treated as described above to calculate the average value, the results are shown in Table 13 below.

Experiment Experiment # 4
(Comparative Example 1) Experiment # 5
(Comparative Example 2) Experiment # 6
(Commercially available bristles) Experiment # 7
Example 11 Before treatment 142 cN 139 cN 141 cN 142 cN After treatment 141 cN 112 cN 123 cN 165 cN increase -One -27 -18 +23

As shown in Table 13, all other treatments showed a decrease in tensile strength, but it can be seen that only Example 11 (Experiment # 7) increased the tensile strength of the hair even after washing with shampoo. Therefore, it can be seen that the composition of the present invention also has the effect of increasing the tensile strength of the hair by preventing the loss of internal components of the hair.

(5) gloss rating

A total of four hairtresses (length 12 cm, weight 3 g) made of damaged hair by bleaching a total of two were prepared, and the gloss was measured by SAMBA (Bossa Nova Tech., US). First, the tress was measured by measuring the front and rear of the tress and treating it with the compositions of Examples and Comparative Examples in the same method and conditions as the method of measuring the change in tensile strength in a state where the shine was set to 8.5.

Experiment Experiment # 4
(Comparative Example 1) Experiment # 5
(Comparative Example 2) Experiment # 6
(Brissam sampu) Experiment # 7
Example 11 Before treatment 8.5 8.5 8.5 8.5 After treatment 8.0 7.0 9.0 19.5 increase -0.5 -1.5 +0.5 +11

As shown in Table 14, the gloss decreases in all the other treatments, but it can be seen that the glossiness was greatly increased only in Example 11. Through this, the composition of the present invention can be seen that the lipid protected during the cleaning process and at the same time has the effect of significantly increasing the gloss on the hair by supplying calm and fine hair.

Claims (21)

Crosslinking mediators and carbodiimide compounds having a carboxyl group or an amine group; Cationic cellulose polymers; And a composition for preventing hair, skin or fiber component loss, comprising polar oil,
The crosslinking mediator having a carboxyl or amine group is polylysine, lysine, polyamine or soy protein (WS-SP),
The carbodiimide compound is polycarbodiimide (PCI),
The hair, skin or fiber component is lipid (lipid), hair, skin or fiber component loss prevention composition. delete The method of claim 1,
The carbodiimide-based compound is a compound comprising an N = C = N structure. delete delete The method of claim 1,
Wherein said cationic cellulose polymer has a nitrogen content of at least 1.5% by weight relative to the total weight of the polymer. The method of claim 1,
The cationic cellulose polymer may be hydrogen bonded to polyethylene oxide or OH bonded to carbons 2 and 3 of the glucose unit in the cellulose skeleton, and the OH site bonded to carbon 6 may not be hydrogen bonded through a linker. And a cationic cellulose polymer having a cationic quaternary ammonium introduced therein, wherein the nitrogen content is at least 1.5% by weight relative to the total weight of the polymer. The method of claim 1,
Wherein said cationic cellulose polymer has a molecular weight of 300,000 to 2.9 million. The method of claim 1,
Wherein said cationic cellulose polymer has a nitrogen content of 1.5% to 3.5% by weight relative to the total weight of the polymer. The method of claim 1,
Wherein said cationic cellulose polymer is a quaternized ammonium salt comprising hydroxy ethyl cellulose and trimethylamine. The method of claim 1,
Wherein said cationic cellulose polymer is a quaternary ammonium salt represented by Formula 1:
[Formula 1]

In Formula 1, α and β are a polyethylene oxide group or OH is bonded, any one of α and β is a polyethylene oxide group is bonded,
x is 1 to 10; n is 1 to 10, y is 0 to 1,
When n is 1, y is 0.3 to 0.7. The method of claim 1,
The polar oil is an oil having an interfacial tension of 150 mN / m or less. The method of claim 1,
The polar oil is isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate Latex, isononyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2-octyldodecyl palmitate, oleyl oleate, oleyl erucate, erucyl Selected from the group consisting of oleate, erucyl erucate, dicaprylyl carbonate (cethiol CC), cocoglycerides (myritol 331), butylene glycol dicaprylate / dicaprate and dibutyl adipate. The tension is 150 mN / m or less. delete The method of claim 1,
Cationic cellulose polymers; And / or from 0.0001 to 10% by weight of polar oil in the total composition. The method of claim 1,
A composition comprising a crosslinking mediator having a carboxyl group or an amine group in an amount of 0.0001 to 10% by weight in the total composition, and a carbodiimide compound in an amount of 0.0001 to 10% by weight in the total composition. The method of claim 1,
0.0001 to 10 wt% of the cationic cellulose polymer in the total composition; 0.0001 to 10 wt% polar oil; And 0.0001 to 10% by weight of the sum of the crosslinking mediator component having a carboxyl group or an amine group and the carbodiimide-based compound. The method of claim 1,
And at least one selected from the group consisting of cationic polymers, surfactants and oils. A composition for treating hair, skin or fibers, which can prevent the loss of hair, skin or fiber components comprising the composition of claim 1. Cleaning composition comprising a composition according to claim 1. Cosmetic composition comprising a composition according to claim 1.

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