KR101985607B1 - Balloon catheter for improving the curative effacement of radiation in rectal cancer and prostate cancer - Google Patents

Abstract

A balloon catheter according to the present invention expands, spreads and fixes a cancer position when treating rectal cancer, thereby effectively performing radiation therapy. In addition, the balloon catheter according to the present invention pressurizes a rectal part corresponding to prostate and makes the rectal wall adhere to prostate when treating prostate cancer by radiation to fix the position of prostate, thereby increasing radiation therapy effects.

Description

[0001] The present invention relates to a balloon catheter for improving the efficacy of radiation therapy for rectal cancer and prostate cancer,

The present invention relates to a balloon catheter, and more particularly, to a method of treating a rectal cancer by radiating the region where the cancer is located to tightly stretch and fix the region where the cancer is located, thereby effectively treating the prostate cancer. The present invention relates to an inflatable catheter that enhances the effect of radiation therapy by pressing or expanding the corresponding rectal portion to fix the position of the prostate by allowing the rectal wall to come into close contact with and pressurize the prostate.

The prostate gland is a biliary-sized gonadal gland that exists only in men.

As shown in FIG. 1, the prostate is in contact with the bladder at the top, fixed by the genitourinary diaphragm at the bottom, tightly fixed to the dorsal bone at the anterior portion of the prostate ligament, It is wrapped. The back of the prostate gland is separated from the rectum by rectal bladder septum (rectal bladder septum), and the urethra passes into the prostate gland.

Prostate cancer occurs mainly in the posterior part of the prostate very close to the rectal wall. Since the prostate gland is a moving tissue of about 5 mm to 20 mm, when treating prostate cancer with radiation, the radiation has to be extensively examined so that most of the rectal wall adjacent to the prostate gland is exposed to radiation.

Accordingly, a method of using a balloon catheter to fix the prostate gland in radiation therapy has been proposed. The balloon catheter includes a balloon and a tube for supporting the balloon. Such a balloon catheter is disclosed in Korean Patent No. 1672934, for example. In this method, the balloon is inserted into the rectum, and then the balloon is inflated using water or air to fix the prostate by closely pressing the rectal wall against the prostate. This method has the advantage of improving the therapeutic effect by minimizing the exposure of the prostate excluding the cancer by fixing the prostate during the radiation treatment.

However, the tube is made of a material having high rigidity to support the balloon. When the tip of the tube strikes the rectum or the anus of the patient, there is a problem that the wound is scarred or the patient is seriously surprised.

On the other hand, the balloon expands when the fluid is introduced and shrinks when the fluid is discharged. However, after the balloon is inserted into the rectum, it is difficult to know whether the balloon is normally inflated. For example, if air is introduced into the balloon after the balloon is inserted into the rectum, but the air is released from the balloon, the balloon does not expand to the normal size, resulting in a problem in that the effect of the radiation treatment is deteriorated.

The tube is marked with a scale, which indicates the depth at which the balloon is inserted. However, the scale printed on the tube may be peeled off due to repetitive use or friction with an external object.

And, as described above, the tube is made of a material having high rigidity, but it may be difficult to obtain the desired rigidity only by the tube.

On the other hand, when radiation is applied to treat rectal cancer, it is necessary to tighten and fix the rectum because the rectal wall is not flat and the rectum continues to move during radiation therapy. For this purpose, it has been proposed to fix the rectal wall flat by using a balloon catheter. The balloon catheter has the same or similar structure as that used for the prostate cancer. The above-described problems also arise when the balloon catheter is applied to rectal cancer.

The present invention has been proposed in order to solve the above problems. In order to solve the above problems, in order to treat a prostate cancer by radiation, a rectal wall corresponding to the prostate gland is pressed or inflated to fix the position of the prostate gland by tightly pressing the rectal wall against the prostate gland, It is an object of the present invention to provide an inflatable catheter that improves the therapeutic effect.

It is another object of the present invention to provide a balloon catheter for enhancing the effect of radiation therapy by expanding a site where a cancer is located to fix rectal cancer in order to treat rectal cancer by radiation.

Another object of the present invention is to provide a method for preventing a balloon from being stabbed in the rectum or anus before the balloon is inserted or withdrawn into the rectum or inserted into the rectum and before the balloon is inflated, And a balloon catheter.

It is a further object of the present invention to provide a method for sealing a tube by enclosing the tube with a shrink tube (third tube), thereby reinforcing the stiffness of the tube, The present invention also provides a balloon catheter that can protect a tube when the balloon catheter is fixed to the balloon catheter.

It is still another object of the present invention to provide a balloon catheter that allows a user to know from outside the balloon normally inflated even after the balloon is inserted into the rectum.

It is still another object of the present invention to provide a balloon catheter that can detect when a balloon is in place when inserting the balloon into the rectum.

In order to solve the above problems, the balloon catheter 100, 200, 300, 400 according to the present invention includes a balloon 10 (16) that expands when the fluid flows in and contracts when the fluid is discharged; A tube 30 serving as a passage for supplying and discharging the fluid to the balloons 10 and 16; And a tip (37) provided at the tip of the tube (30).

A front portion of the tube 30 is installed to be inserted into the inside of the balloon portions 10 and 16 and a valve 50 is provided at a rear end of the tube 30 for controlling supply,

The tip 37 is made of a material that is softer than the tip of the tube 30 so that the balloon 10 or 16 is inserted into the rectum or the tube 30 when the balloon 10 or 16 is non- ) Can be prevented from stimulating the rectum or anus.

The tip 37 may be inserted into the distal end of the tube 30.

The tip 37 may be coupled to the tip 13 of the balloon 10. As an alternative, the tip 37 may be spaced apart from the tip of the balloon 16 when the distance between the tip of the balloon 16 and the tip 37 is too great .

The tip 37 may be provided with a marker 37a. The marker 37a is used to locate the tip 37 on the monitor during CT or X-ray imaging.

An auxiliary pipe (40) branched from the pipe (30) may be connected to the front of the valve (50). The tube 30 and the auxiliary tube 40 communicate with each other to allow the fluid to move, and the auxiliary tube 40 is provided with the auxiliary balloon 42.

When the fluid is supplied, the balloons 10 and 16 are expanded together with the auxiliary balloons 42, so that the balloons 10 and 16 inserted into the rectum can be normally swollen.

It is preferable that the thickness of the auxiliary balloon 42 is thicker than the thickness of the balloon portions 10 and 16. In this case, the auxiliary balloon 42 does not expand any more after being inflated to a certain degree, so that the fluid is only supplied to the balloon portion 10 (16) after inflating to a certain degree.

The valve 50 can supply or block the fluid by pushing or pulling the button 52 in the longitudinal direction of the valve 50 so that the user can press the button 52 with the fingers of the hand holding the syringe It is convenient because you can push or pull.

According to the first, second and third embodiments of the present invention, the tube 30 extends from the rear end 11d to at least a certain portion B of the balloons 10 and 16, (32) and (33).

The first tube 31 has a rigidity enough to support the balloons 10 and 16 when the balloons 10 and 16 are inserted into the rectum and a fluid passage is formed in the first tube 31.

The second tube 32 is installed so as to surround the first tube 31 and the rear end 11d of the balloon 10 and the second tube 32 are joined by an adhesive.

The third pipe 33 is installed from the rear end to the B portion of the balloons 10 and 16 and is provided so as to surround the rear end 11d of the balloons 10 and 16 and the second pipe 32, The rear end 11d of the first and second tubes 10 and 16 is brought into close contact with the outer surface of the second tube 32 so that the bonding by the adhesive is firmly performed. The third tube 33 is not included in the portion of the tube 30 inserted into the inside of the balloons 10 and 16.

The third tube 33 is preferably a shrinkable tube that contracts when heated. Accordingly, the third tube 33 can be brought into close contact with the rear end 11d of the balloon 10, 16 and the second tube 32.

The C portion may be continuous or the A portion and the C portion may be sequentially connected to the rear end of the B portion. The portion A may be composed of only the first and second tubes 31 and 32, and the portion C may be formed only by the second tube 32. The second tube 32 is made of a flexible silicone tube so that the direction of the syringe connected to the valve 50 can be different from the direction of the balloon 10,16.

According to the fourth embodiment of the present invention, the tube 30 includes the first and third tubes 31 and 33 from the rear end of the balloon portions 10 and 16 to at least a certain portion D thereof. The rear end 11d of the balloon portion 10 (16) and the first tube 31 are joined by an adhesive.

The third tube 33 is installed to a predetermined length from the rear end of the balloon 10 and 16 so as to surround the rear end 11d of the balloon 10 and the first tube 31 The rear end 11d of the balloons 10 and 16 is brought into close contact with the outer surface of the first tube 31 so as to be bonded by an adhesive. The third tube 33 is not present in the portion of the tube 30 inserted into the inside of the balloon portions 10 and 16.

The E portion and the C portion can be successively connected to the rear end of the D portion. The E portion is composed of only the first tube 31, and the C portion is composed of the second tube 32 only. The second tube 32 is made of a flexible and flexible silicone tube, so that the direction of the syringe connected to the valve 50 may be different from the direction of the balloon 10 (16).

The present invention has the following effects.

First, in order to treat prostate cancer with radiation, the rectal wall is pressurized or compressed by pressing or expanding the rectal portion corresponding to the prostate gland to fix the position of the prostate gland to enhance the radiation treatment effect.

Second, in order to treat rectal cancer with radiation, the effect of radiation therapy is enhanced by expanding the site where the cancer is located and fixing the position.

Third, the insertion of the balloon into or out of the rectum, or insertion into the rectum, can prevent the tip of the tube from stabbing the rectum or anus before inflating the balloon to prevent scarring or patient surprise.

Fourth, by enclosing the tube with the shrink tube (third tube), it is possible to complement the stiffness of the tube, to secure the balloon to tube connection, to prevent the scale from peeling off, and to fix the tube with the clamp Thereby preventing damage to the pipe.

Fifth, it is easy to see from the outside whether the balloon is normally inflated even after the balloon is inserted into the rectum.

Sixth, when you insert a balloon into the rectum, you can see if the balloon is in the correct position.

FIG. 1 is a view showing a prostate and surrounding tissue. FIG.
2 is a front view showing a balloon catheter according to a first embodiment of the present invention;
3 is a perspective view showing a balloon;
4 is an enlarged view of a cross section IV-IV 'of FIG. 3;
5 is an enlarged view of a portion V in Fig.
6 is an enlarged view of a portion VI in Fig.
Fig. 7 is an enlarged view of a section of the pipe in the section B in Fig. 2; Fig.
8 is a photograph showing the valve.
9 is a front view showing a balloon catheter according to a second embodiment of the present invention.
10 is an enlarged cross-sectional view showing the balloon of FIG. 9;
11 is an enlarged view of a portion XI in Fig. 10; Fig.
12 is a sectional view showing a case where the balloon portion of FIG. 10 is expanded.
13 is a front view showing a balloon catheter according to a third embodiment of the present invention.
FIG. 14 is a front view showing a balloon catheter according to a fourth embodiment of the present invention; FIG.
15 is a view showing insertion of the balloon catheter of FIG. 2 into the rectum for radiotherapy of rectal cancer;

Hereinafter, the present invention will be described in detail with reference to the accompanying drawings. Prior to this, terms and words used in the present specification and claims should not be construed as limited to ordinary or dictionary terms, and the inventor should appropriately interpret the concepts of the terms appropriately It should be interpreted in accordance with the meaning and concept consistent with the technical idea of the present invention based on the principle that it can be defined. Therefore, the embodiments described in the present specification and the configurations shown in the drawings are merely examples of the present invention and are not intended to represent all of the technical ideas of the present invention, so that various equivalents And variations are possible.

First Embodiment

FIG. 2 is a front view showing a balloon catheter according to a first embodiment of the present invention, FIG. 3 is a perspective view showing a balloon of the balloon catheter, and FIG. 4 is an enlarged view of a section IV-IV 'of FIG. Figs. 2 to 4 show a case in which the balloon portion is inflated.

Referring to the drawings, a balloon catheter 100 includes a balloon 10, a tube 30, and a valve 50.

The balloon 10 is inflated by a fluid supplied through the tube 30, for example, air, a saline containing 60% contrast agent (calcium 3), and shrunk when the fluid is evacuated. The balloon 10 may be made of silicone, polyurethane, nylon, PET or the like, preferably transparent so that the inside thereof is visible.

The balloon 10 is completely inflated when approximately 70 ml of water is injected. It is preferable that the balloon 10 is not inflated even if additional pressure is applied to the tube 30 in excess of 70 ml in order to prevent overwork. For this purpose, the balloon 10 can be made by curing a material such as silicon.

The diameter d of the balloon 10 when inflated is preferably 30 mm to 50 mm.

4, the balloon 10 includes a horizontal portion 11a, a first curved portion 11b, a second curved portion 11c, and a rear end 11d. The horizontal portion 11a, the first and second curved portions 11b, 11c, and the rear end 11d are integrally formed.

When the balloon portion 10 is inflated, the horizontal portion 11a is expanded to have a cylindrical shape and the first curved portion 11b is inflated to form a convex curved surface outward from the front side of the horizontal portion 11a, (11c) is expanded to form a convex curved surface outward from the rear of the horizontal portion (11a).

As such, the balloon including the horizontal portion 11a is advantageous in tightening the rectum in comparison with spherical balloons and elliptical balloons, and is advantageous in that the prostate is pressed and fixed laterally through the rectal wall.

At the tip of the balloon 10, a coupling part 13 may be formed. The engaging portion 13 is formed such that the tip of the tip 37 is engaged with the balloon 10 and protrudes outward. A marker 37a (e.g., a platinum marker) may be provided at the tip of the tip 37, which will be described later.

The rear end 11d of the balloon 10 is formed in a cylindrical shape and the tube 30 is inserted into the balloon 10 through the rear end 11d. The rear end 11d is joined to the second tube 32 by an adhesive.

The tube 30 supplies fluid to the balloon 110 or discharges the fluid from the balloon 110. The tube 30 includes a fluid passage therein.

The tube 30 includes first, second and third tubes 31, 32, and 33. 2 and 4, A represents a portion constituted only by the first and second tubes 31 and 32, B represents a portion constituted by the first, second and third tubes 31, 32 and 33, , And C represents a portion composed only of the second tube 32. The portions A to B are formed in a straight line, and the portion C is flexible, so that it can be bent freely.

A portion is inserted into the inside of the balloon portion 10. At the portion A, one or more holes 35 for supplying and discharging the fluid are formed. A valve (50) is provided at the rear of the cylinder (C). The fluid injected by the syringe (or the injection means, not shown in the figure) passes through the portions C, B, and A sequentially through the holes 35, (10). The lengths of the portions A, B and C can be increased or decreased as needed, respectively, than the ratio shown in the figure.

The first and second pipes 31 and 32 are installed to extend from A to B, and the third pipe 33 is installed only to B.

The first tube 31 has a rigidity enough to support the resistance (or external force) received when the balloon 10 is inserted into the rectum and when the radiation therapy is performed. Preferably, the first tube 31 is a tube made of synthetic resin, more preferably a transparent tube made of polycarbonate.

Since the portion A is inserted into the rectum and the portion B is supported by the supporting means (not shown in the figure), the first tube 31 having a predetermined rigidity and being straight is included in the portions A to B do. 2 to 3 of the registration document of Korean Patent Registration No. 1672934, which is a device for supporting a balloon catheter inserted into a rectum during radiation therapy.

The second pipe (32) is installed so as to surround the first pipe (31) in close contact with the outer surface of the first pipe (31). The second tube 32 is preferably made of medical silicone.

As an alternative, the silicon tube may be made thinner, the scale may be printed on the outer surface, and then the silicon tube may be further coated with the second tube 32, . The second tube 32 made in this way is not scaled or erased.

As shown in FIG. 7, the third tube 33 is installed to surround the second tube 32 while being in close contact with the outer surface of the second tube 32. The third tube 33 can be a shrink tube that shrinks when heated, and the shrink tube is commercially available. When the second tube 32 is heated while being inserted into the shrink tube, the shrink tube is brought into close contact with the second tube 32.

6, the rear end 11d of the balloon 10 is joined to the second tube 32 by an adhesive between the second tube 32 and the third tube 33, 33 closely contact the rear end 11d with respect to the second tube 32. [ That is, after the adhesive is applied to the outer surface of the second tube 32, the rear end 11d is coupled to the second tube 32, and then the second tube 32 and the rear end 11d are connected to the third tube 33 And then the third tube 33 is closely contacted by heating.

The third tube 33 compensates the rigidity of the tube 30 and protects the second tube 32 from being damaged due to friction or impact with the outside. When the tube 30 is fastened to the clamp, And protects the two pipes (31) and (32).

And the C portion is continuous at the rear end of the B portion. The C portion consists only of the flexible tube 32, for example a silicone tube. The rear end of the portion B is inserted into the second tube 32 and inserted. The direction of the valve 50 and the balloon portion 10 may be different since the second tube 32 is flexible and flexible so that the user (physician, etc.) can move the valve 50 and the syringe (Not shown in the drawings, fluid is supplied). On the other hand, the syringe can be fastened to the fastening portion 60 at the rear of the valve.

As shown in FIGS. 2 and 8, the valve 50 may supply or block fluid by pushing or pulling the button 52 in its longitudinal direction. Such a valve 50 is sold under the product number 97337 of QOSINA, and can be purchased and used by those skilled in the art.

The user can push or pull the button 52 with the fingers of the hand holding the syringe (not shown in the drawing), since the fluid can be supplied or blocked by pushing or pulling the button 52 in the longitudinal direction of the valve 50 There are advantages. In contrast, a conventional balloon catheter rotated the valve to supply or block the fluid. In this case, since the valve could not be rotated by the hand holding the syringe, it was inconvenient to rotate the valve with the other hand.

After inserting the balloon 10 into the rectum, when the predetermined amount of fluid is supplied, the valve 50 is closed. When the radiation therapy is completed, the valve 50 is opened to discharge the fluid, and then the balloon 10 is taken out of the rectum.

On the other hand, a tip 37 may be provided at the tip of the tube 30. Tip 37 has a smaller stiffness than tube 30 and is therefore soft and flexible. Specifically, the tip 37 is a medical silicone tube having a length of about 0.5 cm to 1.5 cm, preferably about 1 cm, which is inserted into the tip of the tube 30 and is bonded or coated with an adhesive on its outer surface The tube 30 can be inserted into and coupled to the tip of the tube 30. The distal end of the tip 37 can be coupled to the coupling portion 13 by a method such as adhesive, heat fusion, ultrasonic fusion, or the like.

A marker 37a may be provided in the interior of the tip 37. A platinum marker may be used as the marker 37a. The marker 37a helps to grasp the position of the balloon 10 through the monitor when the balloon 10 inserted in the human body is X-ray or CT.

In addition, a hole (not shown in the drawing) may be formed in the tip 37 so as to be used for supplying and discharging the fluid. If the tip 37 is provided with a hole, the hole 35 may not be necessary.

On the other hand, although not shown in the drawings, the radiation amount measuring means may be provided in the balloon portion 10. For example, a radiation dose measuring means may be attached to the outer surface of the balloon 10.

Examples of the radiation dose measuring means include a radiation dosimeter using a radiation sensitive function including a radiation sensitive film or a radiation dosimeter using a radiation ionization action including a diode array plate. The radiation dose measuring means is used to measure the cumulative radiation dose irradiated to the cancer site.

Second Embodiment

FIG. 9 is a front view showing a balloon catheter according to a second embodiment of the present invention, and FIG. 10 is an enlarged cross-sectional view showing the balloon. Figures 9-10 show the case where the balloon portion is not inflated (unexpanded).

Referring to the drawings, a balloon catheter 200 includes a balloon 16, a tube 30, and a valve 50.

The balloon portion 16 is inflated by the fluid supplied through the tube 30 and contracted when the fluid is discharged. The balloon 16 may be made of a material, a size, a degree of expansion after the balloon 16 is expanded to a certain degree, a radiation amount measuring means may be provided in the balloon 16, same.

The tip end of the balloon portion 16 is different from the balloon portion 10 of the first embodiment in that the tip end of the balloon portion 16 is not engaged with the tip 37 and the balloon portion 16 when inflated thereby has a shape as shown in Fig. That is, as shown in Fig. 12, the balloon portion 16 does not have the horizontal portion 11a at the time of inflation.

The rear end 11d of the balloon portion 16 is formed in a cylindrical shape and the structure of the rear end 11d and the structure adhering to the second tube 32 are the same as those of the balloon portion 10 of the first embodiment. The tube 30 is inserted into the balloon portion 16 through the rear end 11d.

The tube 30 includes first, second and third tubes 31, 32, and 33. 9 to 10, A represents a portion constituted only by the first and second tubes 31 and 32, B represents a portion constituted by the first, second and third tubes 31, 32 and 33, And C represents a portion composed only of the second tube 32. The portions A to B are formed in a straight line, and the portion C is flexible and flexible so that it can be bent freely. The tubular structures of the portions A, B and C are the same as in the first embodiment, and the materials of the first, second and third pipes 31, 32 and 33 are the same as those in the first embodiment. And, the lengths of the portions A, B, and C can be increased or decreased as needed, respectively, than the ratio shown in the drawing.

The tube 30 is different from the tube 30 of the first embodiment in that the A portion is located between the B portion and the C portion.

On the other hand, a tip 37 may be provided at the tip of the tube 30. The material of the tip 37, the structure to be coupled with the tube 30, and the fact that the marker 37a can be installed therein are the same as in the first embodiment.

In addition, when the tip 37 is provided with the hole 37b, the tip 37 can be used for supplying and discharging the fluid. In the case where the hole 37b is formed in the tip 37, (35 in Fig. 4) may not be formed.

The tip 37 is spaced apart from the tip of the balloon 16 such that the distal end of the balloon 16 is away from the tip 37 when the balloon 16 is inflated. Therefore, when inserting the balloon catheter 200 into the rectum, when the balloon portion 16 is inflated slightly after the balloon portion 16 is positioned slightly below the correct position, the balloon portion 16 is slightly expanded upward, .

Third Embodiment

13 is a front view showing a balloon catheter according to a third embodiment of the present invention.

Referring to the drawings, a balloon catheter 300 includes a balloon 16, a tube 30, a valve 50, an auxiliary tube 40, and an auxiliary balloon 42. The balloon 16 shown in the figure is in an unexpanded state (unexpanded state).

Compared with the balloon catheters 100 and 200 of the first and second embodiments, the balloon catheter 300 has the auxiliary tube 40 and the auxiliary balloon 42.

Auxiliary tube (40) branches off tube (30) in front of valve (50). The auxiliary balloon 42 is installed at the end of the auxiliary pipe 40. The auxiliary pipe (40) and the pipe (30) are communicated with each other so that the fluid can be moved. Accordingly, when fluid is supplied from the syringe (not shown in the drawing), the fluid is supplied to the balloon 16 through the tube 30 and supplied to the auxiliary balloon 42 through the auxiliary tube 40 The balloon portion 16 and the auxiliary balloon 42 expand together.

At this time, if the balloon 16 inserted into the rectum does not expand normally, for example, if the balloon 16 punctures and the fluid flows out to the rectum, the auxiliary balloon 42 may expand normally By observing the auxiliary balloon 42, the user can easily know whether the balloon 16 is normally inflated or not.

The auxiliary balloon 42 may be formed to be thicker than the balloon portion 16 and is preferably formed to be 1.5 to 3.5 times thicker than the balloon portion 16 and more preferably 2 to 3 times Respectively. When the auxiliary balloon 42 is formed thicker than the balloon portion 16, the auxiliary balloon 42 does not expand any more after the balloon is expanded to a certain degree, ).

The auxiliary balloon 42 is cheaper than the pressure gauge and can easily detect whether the balloon 16 is normally inflated. In addition, the auxiliary balloon 42 has an advantage that it can expand rapidly only by a certain degree, and does not inflate more than a certain degree, so that the balloon 16 can be rapidly inflated.

On the other hand, the lengths of the portions A, B and C can be increased or decreased as needed, respectively, than the ratio shown in the figure.

Fourth Embodiment

14 is a front view showing a balloon catheter according to a fourth embodiment of the present invention.

Referring to the drawings, a balloon catheter 400 includes a balloon portion 16, a tube 30, a valve 50, an auxiliary tube 40, and an auxiliary balloon 42. The balloon 16 shown in the figure is in an unexpanded state (unexpanded state).

Compared with the balloon catheter 300 of the third embodiment, the balloon catheter 400 has a different cross-sectional structure of the tube. Specifically, the tube 30 of the balloon catheter 400 includes first, second, and third tubes 31, 32, and 33, wherein the first tube 31 extends from the inside of the balloon 16, And the second tube 32 is connected to the rear end of the first tube 31 to form the C portion and the third tube 33 is installed only to the D portion. The second tube 32 is not installed in the inside of the balloon 10 and the portions D to E of the balloon 10. And, the lengths of the portions A, C, D, and E can be increased or decreased as needed, respectively, than the ratio shown in the drawing.

Hereinafter, a procedure for radiotherapy of rectal cancer using the balloon catheter 100 will be described.

First, after the tube 30 is attached to the clamp (supporting means), the balloon 10 is inserted into the rectum by advancing the balloon catheter 100 in a state in which the balloon 10 is contracted. At this time, if the relative position of the scale and the clamp engraved in the tube 30 is grasped, the depth at which the balloon 10 is inserted into the rectum can be known. A platinum marker 37a or a copper tape (not shown in the figure) or the like shows the position of the balloon 10 through an X-ray photographing or CT photographing through a monitor (not shown).

When the balloon portion 10 is inserted in the correct position, the valve 50 is opened and the fluid is supplied to inflate the balloon portion 10. At this time, the user can open the valve 50 by moving the button 52 of the valve 50 with the finger of the hand holding the syringe, which is more convenient than the conventional valve.

When the balloon 10 is inflated, the rectum becomes taut and the cancer site is fixed. This process can be performed while observing a monitor or the like.

When the cancer site is tightened and fixed, radiation is applied. The cumulative radiation dose can be measured using a radiation dose measuring means.

When the radiation therapy is completed, the valve 50 is opened and the syringe is retracted to contract the balloon 10, and then the balloon 10 is taken out through the rectum.

As described above, when the balloon 10 is inflated and the arm portion is tightened and fixed, the radiation dose can be intensively applied only to the cancer portion, so that the radiation dose can be minimized in the normal cells around the cancer.

The process of radiotherapy of the prostate cancer using the balloon catheters 100, 200, 300 and 400 is as described above, except that the rectal region corresponding to the prostate gland is inflated or pressurized.

According to the present inventors' clinical studies, radiation therapy for rectal cancer has been performed 15-20 times in the past. When using the balloon catheters 100, 200, 300 and 400, The same treatment effect as the 20th treatment was obtained. In addition, we found that tumor size was reduced by more than 60% compared to conventional methods when the same dose of radiation was examined.

In the above description, the balloon catheters 100 and 200 of the first and second embodiments are described and shown as having no auxiliary tube 40 and auxiliary balloon 42, but the balloon catheters 100 and 200 The auxiliary tube 40 and the auxiliary balloon 42, which will be readily apparent to those skilled in the art.

Although the balloon portion 16 of the second, third and fourth embodiments is described and shown as being separated from the tip 37, the tip of the balloon portion 16 may be engaged with the tip 37. [

100, 200, 300, 400: balloon catheter
10, 16: balloon portion 11a: horizontal portion
11b: first curved portion 11c: second curved portion
11d: rear end of the balloon 13:
30: Pipe 31: 1st pipe
32: the second pipe 33: the third pipe
35: Hole 37: Tips
37a: marker 40: auxiliary tube
42: auxiliary balloon 50: valve
52: Button 60:
d: diameter of inflated balloon 10

Claims (15)

A balloon (10) (16) expanded when the fluid flows in and contracted when the fluid is discharged;
A tube 30 serving as a passage for supplying and discharging the fluid to the balloons 10 and 16; And
And a tip (37) provided at the tip of the tube (30)
A front portion of the tube 30 is installed to be inserted into the inside of the balloon portions 10 and 16 and a valve 50 is provided at the rear end of the tube 30 for controlling the supply,
The tip 37 is made of a material that is softer than the tip of the tube 30 so that when the balloon 10 or 16 is inserted into the rectum or radiation therapy the tip of the tube 30 stimulates the rectum or anus Therefore,
The tube 30 includes the first, second and third tubes 31, 32 and 33 from the rear end 11d to at least a certain portion B of the balloon 10,
The first tube 31 has a rigidity enough to support the balloons 10 and 16 when the balloons 10 and 16 are inserted into the rectum and a fluid passage is formed in the first tube 31,
The second tube 32 is installed so as to surround the first tube 31. The rear end 11d of the balloon 10 and the second tube 32 are joined by an adhesive,
The third tube 33 is installed from the rear end to the B portion of the balloons 10 and 16 and is installed to surround the rear end 11d of the balloons 10 and 16 and the second tube 32, The rear end 11d of the tube 10 is brought into close contact with the outer surface of the second tube 32 so as to be coupled by the adhesive. The third tube 33 is not included in the inserted portion,
The third tube 33 is a shrink tube that contracts when heated so that the third tube 33 is closely attached to the rear end 11d of the balloon 10 and the second tube 32 , A balloon catheter to improve the effectiveness of radiation therapy for rectal cancer and prostate cancer. The method according to claim 1,
The tip 37 is inserted into the tip of the tube 30,
A balloon catheter for enhancing the radiation treatment effect of rectal cancer and prostate cancer, wherein the tip (37) is coupled to the tip (13) of the balloon (10). The method according to claim 1,
The tip 37 is inserted into the tip of the tube 30,
The tip 37 is separated from the tip of the balloon 16 so that the distance between the tip of the balloon 16 and the tip 37 is distanced when the balloon 16 is inflated. And a balloon catheter to improve the radiotherapy effect of prostate cancer. The method according to claim 1,
The tip 37 is provided with a marker 37a,
Wherein the marker (37a) is used to locate the tip (37) on the monitor during CT or X-ray imaging. A balloon (10) (16) expanded when the fluid flows in and contracted when the fluid is discharged;
A tube 30 serving as a passage for supplying and discharging the fluid to the balloons 10 and 16; And
And a tip (37) provided at the tip of the tube (30)
A front portion of the tube 30 is installed to be inserted into the inside of the balloon portions 10 and 16 and a valve 50 is provided at the rear end of the tube 30 for controlling the supply,
The tip 37 is made of a material that is softer than the tip of the tube 30 so that when the balloon 10 or 16 is inserted into the rectum or radiation therapy the tip of the tube 30 stimulates the rectum or anus Therefore,
An auxiliary pipe 40 branched from the pipe 30 is connected to the front of the valve 50. The pipe 30 and the auxiliary pipe 40 are connected to each other to allow the fluid to move, , The auxiliary balloon 42 is provided and the auxiliary balloon 42 is not inserted into the rectum,
When the fluid is supplied, the balloons 10 and 16 are expanded together with the auxiliary balloons 42 so that the balloons 10 and 16 inserted into the rectum can be normally swollen. , A balloon catheter to improve the effectiveness of radiation therapy for rectal cancer and prostate cancer. 6. The method of claim 5,
The thickness of the auxiliary balloon 42 is thicker than the thickness of the balloon portions 10 and 16,
Characterized in that the auxiliary balloon (42) is no longer inflated after a certain degree of expansion, and thus the fluid is only supplied to the balloon (10) (16) after inflating to a certain extent. A balloon catheter to increase the effectiveness of treatment. A balloon (10) (16) expanded when the fluid flows in and contracted when the fluid is discharged;
A tube 30 serving as a passage for supplying and discharging the fluid to the balloons 10 and 16; And
And a tip (37) provided at the tip of the tube (30)
A front portion of the tube 30 is installed to be inserted into the inside of the balloon portions 10 and 16 and a valve 50 is provided at the rear end of the tube 30 for controlling the supply,
The tip 37 is made of a material that is softer than the tip of the tube 30 so that when the balloon 10 or 16 is inserted into the rectum or radiation therapy the tip of the tube 30 stimulates the rectum or anus Therefore,
The valve 50 is installed in the longitudinal direction of the tube 30 and the button 52 of the valve 50 is pushed or pulled in the longitudinal direction to supply or block the fluid, A balloon catheter for enhancing the radiation therapy effect of rectal cancer and prostate cancer, wherein the fluid is supplied or blocked by pushing or pulling the button (52) with a finger. 8. The method according to any one of claims 5 to 7,
The tube 30 includes the first, second and third tubes 31, 32 and 33 from the rear end 11d to at least a certain portion B of the balloon 10,
The first tube 31 has a rigidity enough to support the balloons 10 and 16 when the balloons 10 and 16 are inserted into the rectum and a fluid passage is formed in the first tube 31,
The second tube 32 is installed so as to surround the first tube 31. The rear end 11d of the balloon 10 and the second tube 32 are joined by an adhesive,
The third tube 33 is installed from the rear end to the B portion of the balloons 10 and 16 and is installed to surround the rear end 11d of the balloons 10 and 16 and the second tube 32, The rear end 11d of the tube 10 is brought into close contact with the outer surface of the second tube 32 so as to be coupled by the adhesive. The third tube 33 is not included in the inserted portion,
The third tube 33 is a shrink tube that contracts when heated so that the third tube 33 is closely attached to the rear end 11d of the balloon 10 and the second tube 32 , A balloon catheter to improve the effectiveness of radiation therapy for rectal cancer and prostate cancer. 9. The method of claim 8,
In the tube 30, the C portion is continuous or the A portion and the C portion are successively connected to the rear end of the B portion,
The portion A consists of only the first and second pipes 31 and 32, the portion C includes only the second pipe 32,
Characterized in that the second tube (32) is made of a flexible and flexible silicone tube, whereby the direction of the syringe connected to the valve (50) can be different from the direction of the balloon (10) A balloon catheter to improve radiation therapy of rectal cancer and prostate cancer. A balloon (10) (16) expanded when the fluid flows in and contracted when the fluid is discharged;
A tube 30 serving as a passage for supplying and discharging the fluid to the balloons 10 and 16; And
And a tip (37) provided at the tip of the tube (30)
A front portion of the tube 30 is installed to be inserted into the inside of the balloon portions 10 and 16 and a valve 50 is provided at the rear end of the tube 30 for controlling the supply,
The tip 37 is made of a material that is softer than the tip of the tube 30 so that when the balloon 10 or 16 is inserted into the rectum or radiation therapy the tip of the tube 30 stimulates the rectum or anus Therefore,
The tube 30 includes the first and third tubes 31 and 33 from the rear end of the balloons 10 and 16 to at least a certain portion D,
The first tube 31 has a rigidity enough to support the balloons 10 and 16 when the balloons 10 and 16 are inserted into the rectum and a fluid passage is formed in the first tube 31,
The rear end 11d of the balloons 10 and 16 and the first tube 31 are joined by an adhesive,
The third pipe 33 is installed to a predetermined length from the rear end of the balloons 10 and 16 so as to surround the rear end 11d of the balloons 10 and 16 and the first pipe 31, The rear end 11d of the tube 10 is brought into close contact with the outer surface of the first tube 31 so as to be coupled by the adhesive. The third tube 33 is not included in the inserted portion,
The third tube 33 is a shrink tube that contracts when heated so that the third tube 33 is in close contact with the first tube 31 and the rear end 11d of the balloon 10, , A balloon catheter to improve the effectiveness of radiation therapy for rectal cancer and prostate cancer. 11. The method of claim 10,
In the tube 30, the E portion and the C portion are successively connected to the rear end of the D portion,
E portion is composed of only the first tube 31, the C portion is composed of only the second tube 32,
Characterized in that the second tube (32) is made of a flexible and flexible silicone tube, whereby the direction of the syringe connected to the valve (50) can be different from the direction of the balloon (10) A balloon catheter to improve radiation therapy of rectal cancer and prostate cancer. A balloon (10) (16) expanded when the fluid flows in and contracted when the fluid is discharged; And
And a tube (30) serving as a passage for supplying and discharging the fluid to the balloons (10) and (16)
A front portion of the tube 30 is installed to be inserted into the inside of the balloon portions 10 and 16 and a valve 50 is provided at the rear end of the tube 30 for controlling the supply,
The tube 30 comprises first, second and third tubes 31, 32 and 33 from the rear end 11d of the balloon 10 to at least a certain portion B,
The first tube 31 has a rigidity enough to support the balloons 10 and 16 when the balloons 10 and 16 are inserted into the rectum and a fluid passage is formed in the first tube 31,
The second pipe (32) is installed so as to surround the first pipe (31)
The third pipe 33 is installed to a predetermined length from the rear end of the balloons 10 and 16 so as to surround the rear end 11d of the balloons 10 and 16 and the second pipe 32,
An adhesive is applied to the outer surface of the second tube 32 corresponding to the rear end 11d of the balloon portions 10 and 16 so that the second tube 32 and the rear end 11d of the balloon portions 10 and 16 And the third tube 33 makes the rear end 11d of the balloon 10 and the tube 16 adhere to the second tube 32,
The third tube 33 is not included in the portion of the tube 30 inserted into the inside of the balloons 10 and 16,
The third tube 33 is a shrink tube that is contracted when heated so that the third tube 33 is in close contact with the rear end 11d of the balloon 10 and the outer surface of the second tube 32 A balloon catheter to enhance the radiotherapy effect of rectal cancer and prostate cancer. A balloon (10) (16) expanded when the fluid flows in and contracted when the fluid is discharged; And
And a tube (30) serving as a passage for supplying and discharging the fluid to the balloons (10) and (16)
A front portion of the tube 30 is installed to be inserted into the inside of the balloon portions 10 and 16 and a valve 50 is provided at the rear end of the tube 30 for controlling the supply,
The tube 30 includes the first and third tubes 31 and 33 from the rear end 11d of the balloon 10 to at least a certain portion D,
The first tube 31 has a rigidity enough to support the balloons 10 and 16 when the balloons 10 and 16 are inserted into the rectum and a fluid passage is formed in the first tube 31,
The third tube 33 is installed at a predetermined length from the rear end 11d of the balloon 10 and 16 so as to surround the rear end 11d of the balloon 10 and the first tube 31 And,
The rear end 11d of the balloon 10 and the outer surface of the first tube 31 are joined by an adhesive and the third tube 33 is joined to the rear end 11d of the balloon 10, Is brought into close contact with the first tube (31)
The third tube 33 is not present in the portion of the tube 30 which is inserted into the inside of the balloons 10 and 16,
The third tube 33 is a shrink tube that contracts when heated so that the third tube 33 is in close contact with the rear end 11d of the balloon 10 and the first tube 31 , A balloon catheter to improve the effectiveness of radiation therapy for rectal cancer and prostate cancer. The method according to claim 12 or 13,
An auxiliary pipe 40 branched from the pipe 30 is connected to the front of the valve 50. The pipe 30 and the auxiliary pipe 40 communicate with each other to allow the fluid to move, An auxiliary balloon 42 is installed,
When the fluid is supplied, the balloons 10 and 16 are expanded together with the auxiliary balloons 42 so that the balloons 10 and 16 inserted into the recto can be normally swollen, 42 are thicker than the thickness of the balloon portions 10, 16, the auxiliary balloon 42 does not expand any more after a certain degree of expansion, and after the balloon portion 10 is inflated to a certain degree, (16). ≪ Desc / Clms Page number 15 > 16. A balloon catheter for enhancing the radiation therapy effect of rectal cancer and prostate cancer. The method according to claim 12 or 13,
The valve 50 may feed or block the fluid by pushing or pulling the button 52 in the longitudinal direction of the valve 50 so that the user can push or pull the button 52 with the finger of the hand holding the syringe And a balloon catheter for enhancing the radiation therapy effect of rectal cancer and prostate cancer.

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