KR101968732B9 - 세포소기관에서 자가조립 가능한 펩타이드 분자를 포함하는 접합체 및 이를 포함하는 암의 예방 또는 치료용 약학 조성물 - Google Patents
세포소기관에서 자가조립 가능한 펩타이드 분자를 포함하는 접합체 및 이를 포함하는 암의 예방 또는 치료용 약학 조성물Info
- Publication number
- KR101968732B9 KR101968732B9 KR1020160152392A KR20160152392A KR101968732B9 KR 101968732 B9 KR101968732 B9 KR 101968732B9 KR 1020160152392 A KR1020160152392 A KR 1020160152392A KR 20160152392 A KR20160152392 A KR 20160152392A KR 101968732 B9 KR101968732 B9 KR 101968732B9
- Authority
- KR
- South Korea
- Prior art keywords
- conjugates
- assembling
- self
- pharmaceutical composition
- same
- Prior art date
Links
- 210000003463 organelle Anatomy 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/548—Phosphates or phosphonates, e.g. bone-seeking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160152392A KR101968732B1 (ko) | 2016-11-16 | 2016-11-16 | 세포소기관에서 자가조립 가능한 펩타이드 분자를 포함하는 접합체 및 이를 포함하는 암의 예방 또는 치료용 약학 조성물 |
| US15/813,646 US11083798B2 (en) | 2016-11-16 | 2017-11-15 | Conjugate including peptide molecule capable of self-assembly in cell organelle and pharmaceutical composition for preventing or treating cancer including conjugate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160152392A KR101968732B1 (ko) | 2016-11-16 | 2016-11-16 | 세포소기관에서 자가조립 가능한 펩타이드 분자를 포함하는 접합체 및 이를 포함하는 암의 예방 또는 치료용 약학 조성물 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| KR20180055062A KR20180055062A (ko) | 2018-05-25 |
| KR101968732B1 KR101968732B1 (ko) | 2019-08-13 |
| KR101968732B9 true KR101968732B9 (ko) | 2022-01-24 |
Family
ID=62106400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020160152392A KR101968732B1 (ko) | 2016-11-16 | 2016-11-16 | 세포소기관에서 자가조립 가능한 펩타이드 분자를 포함하는 접합체 및 이를 포함하는 암의 예방 또는 치료용 약학 조성물 |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US11083798B2 (ko) |
| KR (1) | KR101968732B1 (ko) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102584556B1 (ko) * | 2018-05-18 | 2023-10-04 | 울산과학기술원 | 자가조립 펩타이드 분자를 포함하는 접합체 및 그의 용도 |
| CN109627264B (zh) * | 2018-08-21 | 2021-01-05 | 河北大学 | 靶向线粒体苝酐荧光探针及其合成方法和应用 |
| KR102329285B1 (ko) * | 2019-09-17 | 2021-11-19 | 울산과학기술원 | 세포소기관에서 자기조립 가능한 펩타이드 분자를 포함하는 접합체의 d-거울상이성질체 및 l-거울상이성질체가 공동으로 조립되어 형성된 자기조립체 및 이를 포함하는 암의 예방 또는 치료용 약학 조성물 |
| KR102596981B1 (ko) * | 2019-10-30 | 2023-10-31 | 주식회사 퓨전바이오텍 | 미토콘드리아 표적 화합물 및 이를 포함하는 노화 관련 질환의 치료 또는 예방을 위한 조성물 |
| KR102467024B1 (ko) | 2020-07-08 | 2022-11-14 | 울산과학기술원 | 자가조립 및 역자가조립 가능한 pH 감응성 펩타이드 분자를 포함하는 접합체 및 이의 용도 |
| CN115417898B (zh) * | 2022-08-02 | 2024-03-26 | 浙江工业大学 | 一种三苯基鏻单体化合物及其制备方法与在制备核酸递送纳米载体中的应用 |
-
2016
- 2016-11-16 KR KR1020160152392A patent/KR101968732B1/ko active IP Right Grant
-
2017
- 2017-11-15 US US15/813,646 patent/US11083798B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20180133330A1 (en) | 2018-05-17 |
| KR101968732B1 (ko) | 2019-08-13 |
| US11083798B2 (en) | 2021-08-10 |
| KR20180055062A (ko) | 2018-05-25 |
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| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| G170 | Publication of correction |