KR101928842B1 - Manufacturing method of gold nanoparticle with well-defined size through wire explosion in liquid - Google Patents

Abstract

The present invention relates to a manufacturing method of a gold nanoparticle through wire explosion in a liquid and, more specifically, relates to a manufacturing method of a gold nanoparticle, which comprises the following steps of: (1) preparing a gold wire of which a diameter and a supplied length are different; (2) preparing a liquid to perform wire explosion; (3) preparing the wire explosion by supplying voltage to the wire; and (4) performing the wire explosion from ten times to one hundred times. As stated above, according to the present invention, provided is a gold nanoparticle that is not harmful for a human body and has a well-defined size with high yield. Moreover, the manufacturing method of a gold nanoparticle can be utilized for a bio-field such as disease and microorganism analysis, wherein the gold nanoparticle has not been applied to the bio-field.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for manufacturing a gold nanowire having a uniform particle size through a liquid electrodeposition explosion method,

The present invention relates to a method for manufacturing uniform gold nano that can be used in various fields, and more particularly, to a method for manufacturing a new gold nano which is harmless to the human body, .

In the industry, gold wires are used to electrically connect silicon chips and leadframes in the semiconductor field. In the bio-field, the gold surface plasmon is utilized for the analysis of diseases and microorganisms.

As the gold is manufactured / processed into various types of nanoparticles, the utilization range of gold has been further diversified and the application of the previously applied fields has been further increased. Gold nanoparticles are known to exhibit superior biocompatibility to contrast agents and other metals or metal oxides intended for therapeutic use. In addition, it has excellent characteristics in terms of target efficiency and surface processability, and is being actively used in the field of biotechnology.

On the other hand, for the application of gold nano in various industrial fields, uniformity of particle size is secured and low cost synthesis is required. Currently, there is a method of preparing a gold precursor by reduction reaction in a liquid phase using HAuCl _{4 ·} 4H ₂ O. Since the particle size is not uniform and the use of an organic solvent is necessary, It is known to be impossible. Another method is the deposition method using Polydimethylsiloxane (PDMS). In this case, the produced gold nano has a high purity and is used in the field of cosmetics. However, in the case of the gold nano thus produced, a small amount of PDMS remains and is absorbed into the body It can not be used for the analysis of diseases and microorganisms because it can act as a toxic substance. The electric explosion method is a phenomenon in which when a current is supplied to a gold wire to be heated, the wire is transformed into a plasma state and finally gold fine particles are formed. This is because the organic solvent and the organic compound are not used as compared with other methods, and the gold nano produced through the method is highly applicable in the bio field. Among electric explosion methods, the liquid electrodeposition explosion method which is carried out in the liquid phase can prevent the aggregation phenomenon which is stuck to each other in the process of recovering the nanoparticles produced compared to the gas explosion electrodeposition method on the gas phase, It is possible. This is because it makes it possible to synthesize high-purity metal particles by minimizing the possibility of surface oxidation by reducing the chance of particles meeting with oxygen because it is produced in solution.

Accordingly, the present inventors have proposed a method for manufacturing gold nano that is harmless to human body and has a high yield and uniform particle size than gold nanoparticles through conventional manufacturing techniques by applying liquid electrostatic explosion method to produce uniform gold nanoparticles do.

Korean Patent Laid-Open No. 10-2016-0011791 entitled " Method for producing epoxy composite material containing metal nano powder by submerged electric explosion method. &Quot;

It is an object of the present invention to provide a method for manufacturing gold nano through submerged electric explosion method, and it is possible to lower the cost of manufacturing by virtue of the fact that there is almost no loss of gold compared to the liquid or vacuum deposition method which is a conventional manufacturing method, To provide a gold nano-free manufacturing method. The present invention also provides a method for producing gold nanoparticles having a uniform particle size in a small size.

In order to accomplish the above object, the present invention provides a method for manufacturing new gold nanoparticles.

In the gold nanoparticle manufacturing method of the present invention, 1) preparing a gold wire having a different diameter and a supply length, 2) preparing a liquid to be subjected to the electric explosion method, 3) supplying a voltage to the wire, And 4) performing the electric explosion number of the electric explosion method 10 to 100 times.

Further, the present invention provides a method for producing gold nanoparticles which is smaller and more uniform than the conventional manufacturing method, has almost no gold loss, and has very low human harmfulness.

According to the present invention as described above, it is possible to manufacture a new gold nano having a uniform particle size through an electric explosion method.

In addition, when manufacturing the gold nano according to the present invention, it is possible to control the particle size of the gold nano when the conditions are different, and it is effective for applications where gold nano size and uniformity are important.

Fig. 1 is a schematic diagram of an apparatus for submerged electric explosion.
FIG. 2 is a color change image of a gold nanocolloid solution according to the sizes of the gold nanoparticles produced by the manufacturing methods of Examples 7 to 14. FIG.
FIG. 2 is a TEM image of gold nanoparticles prepared in Examples 8 and 11.

Hereinafter, the present invention will be described in detail.

1) preparing a gold wire having different diameter and supply length, 2) preparing a liquid to be subjected to an electric explosion method, 3) supplying a voltage to the gold wire, , And 4) further performing 10 to 100 times of the electric explosion of the electric explosion method.

1) The diameter of the gold wire may be 0.1 to 1.0 mm in the step of preparing the gold wire having a different diameter and a supply length.

1) The supply length of the gold wire in the step of preparing the gold wire different in diameter and supply length may be 10 to 50 mm.

In preparing the liquid to be subjected to the 2) electric explosion method, the liquid may include one or more of water, ethanol, and ethylene glycol.

3) The voltage of the step of supplying voltage to the gold wire to prepare the electric explosion method may be 0.5 to 1.5 kV.

In particular, the number of explosions affects the concentration of gold nano-particles in the liquid phase. The gold nanoparticle concentration in the liquid phase is too low to be used for industrial purposes, and it is preferable that the gold nanoparticles are used up to 100 times because there is no large change in concentration on the basis of 100 times.

Since the manufacturing process of the present invention is performed in a chamber containing a solution, it is possible to collect almost all the nanoparticles produced from the wire without loss of raw materials after the production. Therefore, the yield of gold nanoparticles is higher than that of conventional gold nanoparticles, which are produced by-products.

Unlike the liquid phase method in which gold nanoparticles are formed in the gold precursor solution to control the size of the particles, the manufacturing method of the present invention is a method in which gold is broken into small pieces of gold wire by electric explosion. This method can be used to fabricate small and small gold nanoparticles. As a result, it is possible to produce gold nanoparticles having a size of 10 nm or less by the process of the present invention.

In the case of the gold nanoparticles produced by the manufacturing method of the present invention, the reactivity changes according to the change of color, absorption rate and band gap according to the particle size. Therefore, it is recognized that uniform particle size is a very important factor to have constant reactivity.

Accordingly, the present invention can provide a method for producing gold nanoparticles which is smaller and more uniform than conventional methods, and which is almost free from gold loss and has a very low toxicity to human body through the above-described manufacturing method.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood by those skilled in the art that these examples are for illustrative purposes only and that the scope of the present invention is not construed as being limited by these examples.

Example 1.

For the production of gold nanoparticles, submerged electric explosion was carried out. A gold wire having a diameter of 0.1 mm and a supply length of 50 mm was used. The solvent was ethanol and the supply voltage was set to 0.5 kV and explosion was carried out 20 times.

Example 2.

The procedure of Example 1 was repeated except that the solvent was distilled water.

Example 3.

The procedure of Example 2 was repeated except that the solvent was ethylene glycol.

Example 4.

The procedure was carried out in the same manner as in Example 3, except that a gold wire having a diameter of 0.3 mm was used, and the solvent was ethanol.

Example 5.

The procedure was performed in the same manner as in Example 4, except that a gold wire having a diameter of 0.5 mm was used.

Example 6.

The procedure was carried out in the same manner as in Example 5, except that a gold wire having a diameter of 0.1 mm and a supply length of 35 mm was used.

Example 7.

The same procedure as in Example 6 was carried out except that a gold wire having a supply length of 50 mm and a supply voltage of 1.0 kV were used.

Example 8.

The procedure of Example 7 was repeated except that the solvent was distilled water.

Example 9.

The procedure of Example 8 was followed except that the solvent was ethylene glycol.

Example 10.

The procedure of Example 9 was repeated except that the mixture of ethylene glycol and distilled water was mixed with the mixture of ethylene glycol and distilled water at a volume ratio of 1: 1.

Example 11.

The procedure of Example 10 was repeated except that ethanol was used as the solvent and the supply voltage was 1.5 kV.

Example 12.

The procedure of Example 11 was repeated except that the solvent was distilled water.

Example 13.

The procedure was carried out in the same manner as in Example 12, except that a gold wire having a feed length of 30 mm was used and the solvent was ethylene glycol.

Example 14.

The same procedure as in Example 13 was carried out except that a gold wire having a feed length of 20 mm and a solvent were a mixed solution of ethylene glycol and distilled water and the mixture ratio of the mixture of ethylene glycol and distilled water was mixed at a volume ratio of 1: Respectively.

Table 1 summarizes the preparation conditions of gold nanoparticles of Examples 1 to 14, and Table 2 shows average measured sizes of gold nanoparticles prepared by performing Examples 1 to 14.

Sample name Diameter of gold wire (mm) Supply length of gold wire (mm) Types of solvents Supply voltage
(kV) Number of explosions
(time) Example 1 0.1 50 ethanol 0.5 20 Example 2 0.1 50 Distilled water 0.5 20 Example 3 0.1 50 Ethylene glycol 0.5 20 Example 4 0.3 50 ethanol 0.5 20 Example 5 0.5 50 ethanol 0.5 20 Example 6 0.1 35 ethanol 0.5 20 Example 7 0.1 50 ethanol 1.0 20 Example 8 0.1 50 Distilled water 1.0 20 Example 9 0.1 50 Ethylene glycol 1.0 20 Example 10 0.1 50 Ethylene glycol /
Distilled water mixture 1.0 20 Example 11 0.1 50 ethanol 1.5 20 Example 12 0.1 50 Distilled water 1.5 20 Example 13 0.1 30 Ethylene glycol 1.5 20 Example 14 0.1 20 Ethylene glycol /
Distilled water mixture 1.5 20

Sample name Average particle size (nm) Example 1 180.6 Example 2 135.4 Example 3 85.3 Example 4 202.2 Example 5 250.6 Example 6 90.3 Example 7 45.6 Example 8 43.2 Example 9 29.8 Example 10 22.1 Example 11 32.9 Example 12 25.7 Example 13 18.9 Example 14 9.6

Having described specific portions of the present invention in detail, those skilled in the art will appreciate that these specific embodiments are merely preferred embodiments and that the scope of the present invention is not limited thereby. something to do. Accordingly, the actual scope of the present invention will be defined by the appended claims and their equivalents.

Claims (5)

In a gold nano-manufacturing method,
1) preparing a gold wire having a diameter and a supply length different from each other;
2) preparing a liquid to be subjected to the electric explosion method;
3) supplying a voltage to the gold wire to perform electric explosion; And
4) performing the electric explosion number of the electric explosion method 20 times,
The diameter is 0.1 mm,
The feed length is 20 mm,
Wherein the liquid is a mixture of distilled water and ethylene glycol,
The mixing ratio of the distilled water to the ethylene glycol mixture was 1: 1 by volume,
The voltage is 1.5 kV,
Wherein the gold nanoparticles have an average particle size of 10 nm or less.
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