KR101925209B1 - Biodegradable multi-component filament, surgical thread and operation tool for the lifting using the same - Google Patents

Abstract

The present invention relates to a multi-component multifilament capable of controlling biodegradability, and a suture 50 for facial and body lifting using the multi-filament multifilament. More particularly, the present invention relates to a multi-filament multifilament comprising a plurality of monofilaments made of biodegradable polymer materials having different biodegradation rates, The present invention relates to a biodegradable multicomponent multifilament manufactured by blading, a suture 50 for facial and body lifting using the multifilament, and a surgical instrument.

Description

TECHNICAL FIELD The present invention relates to a biodegradable multi-component filament, a biodegradable multi-component filament, a surgical thread and an operation tool for the lifting using the same,

The present invention relates to a biodegradable multicomponent multifilament prepared by folding or braiding a plurality of monofilaments having different biodegradation rates. More particularly, the present invention relates to a biodegradable multi-filament multifilament comprising a plurality of biodegradable polymeric materials that are biodegradable when inserted into a human body, the biodegradable polymer material being sequentially decomposed according to the biodegradation rate of the monofilaments to induce tissue regeneration, The present invention relates to a suture and a surgical instrument for facial and body lifting.

Modern people have a special interest in the beauty of the body part exposed to the face or the outside, and the word 'for' is accepted as a bigger praise than the word 'beautiful' because of the hot air recently. Therefore, during the recent years, the procedure is in vogue, and during this period, one of the representative procedures of the procedure is lifting procedure. Such a thread lifting procedure is a mid-level procedure between a laser and a surgical operation, and is gaining popularity as it can achieve the same effect as surgery without burdening the daily life.

The thread lifting procedure is a surgical procedure in which the lifting suture 50 is stretched and inserted into a subcutaneous layer of the obtuse skin, and then the skin is lifted in a desired direction. In the region where the lifting suture 50 is inserted, collagen which regulates skin elasticity is regenerated to prevent wrinkles and skin sagging, and fiberization in the dermis proceeds, thereby increasing the elasticity of the skin.

There are various kinds of sutures used in the thread lifting procedure, and various effects can be obtained depending on the types of the sutures. That is, the suture used in the thread lifting procedure is absorbed into the living body by natural decomposition after a certain period of time according to the in vivo absorbability, and the absorbable suture remains unbroken after the tissue is joined. And non-absorbable sutures.

The absorbable suture is biodegraded with time after its insertion into the human body and its strength is lowered. However, sutures differ in initial strength, strength retention, and biodegradation characteristics depending on the site of operation. In general, biodegradable sutures commonly used are reduced to 50 ~ 80% of initial strength after 2 weeks and decreased to 10 ~ 30% after 4 weeks. The polydioxanone suture used for lifting retains its strength up to 60 ~ 80% after 4 weeks and retains about 50% strength after 6 weeks. Therefore, it is very important to adjust the biodegradation rate of the suture to maintain a certain strength or higher until the lifting effect is maximized.

Polydioxanone (PDO), polypropylene (PP), poly-capcolactone (PCL), polylactic acid (PLA), and polylactic acid (PLA) are disclosed in Korean Patent No. 10-1455683 Chitosan, and combinations thereof. The suture of the present invention is excellent in biodegradability. However, the above-described lifting suture is made of a single-component polymer material and has a problem in that it is impossible to control the biodegradation speed and the strength maintenance rate. .

Korean Patent Laid-Open Publication No. 10-1999-010319 (Feb. 18, 1999) discloses a two-component surgical suture prepared by complex spinning of a two-component polymer capable of adjusting the strength retention and biodegradability. However, this method is complicated because of the complex spinning of two-component polymers capable of regulating biodegradability, and the polymer material is limited.

In the manufacture of absorbable sutures, conventionally, a single type of biodegradable polymer material is used to produce a single-lifting suture, resulting in only a single component characteristic. In addition, the two-component absorbent suture has a problem in that its manufacturing process is complicated and the material of the polymer is limited. Therefore, it is difficult to produce a suture having optimal characteristics satisfying various biodegradation characteristics.

The biodegradability and the strength retention ratio can be arbitrarily adjusted according to the characteristics of the body part to be used by utilizing various polymer materials having different biodegradation speeds in the human body due to the above reasons, And there is an urgent need to develop a lifting suture and a surgical procedure which are easy to perform.

As described above, the present invention relates to a biodegradable multicomponent multifilament prepared by folding a plurality of monofilaments having different biodegradation rates, and is characterized in that it is decomposed sequentially in accordance with the biodegradation rate of the monofilament upon insertion into the human body, The present invention relates to a suture for facial and body lifting and a surgical instrument therefor. However, these problems are exemplary and do not limit the scope of the present invention.

In order to solve the above problems, the biodegradable multicomponent multifilament for manufacturing the facial and body lifting suture 50 of the present invention is characterized in that monofilaments made of a plurality of biodegradable polymer materials having different biodegradation rates are folded or bladed . Particularly, the plurality of biodegradable polymer materials may be selected from the group consisting of polydioxanone, polylactic acid, polycaprolactone, polyhydroxybutyrate, and polyglycolic acid. selected from the group, or a para-dioxanone (p -dioxanone), glycolide (glycolide), El-lactide (L -lactide), D-lactide (D -lactide), ε-caprolactone (ε- caprolactone, and trimethylenecabonate are preferably copolymerized with one or more monomers selected from the group consisting of caprolactone and trimethylenecabonate. The monofilament is preferably 1 to 500 denier, and the thickness of the biodegradable multicomponent multifilament is preferably 0.03 to 2.0 mm. The monofilament for doubling or blending is preferably 2 to 24 strands, and a twist may further be imparted when the monofilaments are folded.

In addition, the present invention provides a suture 50 for facial and body lifting comprising the biodegradable multicomponent multifilament, and a suture thread 50 for insertion of a suture 50 for face and body lifting is provided at an upper end portion of one side, A needle (10) including a cap (20) including a hole (30) and a cap end member located at a lower end portion of the other end to be engaged with a handle which is held by a practitioner and is easy to perform; A handle coupled to the hole-piercing end member 40 for facilitating an operation by a practitioner; And a face and a body lifting suture (50) which is inserted into the nostril upper hole (30) to be inserted into the face or the body, and a body and lifting apparatus.

The biodegradable multicomponent multifilament of the present invention and the suture 50 for facial and body lifting using the biodegradable multicomponent multifilament according to the present invention are characterized in that the biodegradable polymer and the strength maintenance ratio after the biodegradable polymer which produce monofilaments constituting the biodegradable multicomponent multifilament Any adjustment is possible. In addition, after lifting suture 50 is applied to the face or the body, the lifting suture 50 (see FIG. 5), which is capable of maintaining a predetermined strength or more until the living tissue is regenerated and joined, ) And a treatment instrument may be provided. The suture 50 for facial and body lifting according to the present invention is manufactured by folding or blending a plurality of monofilaments so that both the suture shape and the twisted shape are possible and the thickness of the suture can be adjusted, The number of procedures can be reduced to double the effect of the procedure. Of course, the scope of the present invention is not limited by these effects.

1 is a schematic view of a lifting suture in which monofilaments are folded (a) or bladed (b)
2 is a pictorial view of a treatment device for facial and body lifting according to an embodiment of the present invention,
3 is a pictorial view of a face and body lifting instrument having a securing member for securing a suture according to one embodiment of the present invention.

The use of the terms "comprises", "having", or "having" in this application is intended to specify the presence of stated features, integers, steps, components, parts, or combinations thereof, But do not preclude the presence or addition of features, numbers, steps, operations, components, parts, or combinations thereof.

Also, unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms such as those defined in commonly used dictionaries are to be interpreted as having a meaning consistent with the contextual meaning of the related art and are to be interpreted as either ideal or overly formal in the sense of the present application Do not.

Hereinafter, the biodegradable multicomponent multifilament according to the present invention, the suture 50 for facial and body lifting using the multifilament, and a surgical instrument will be described in detail.

(PDL), poly-L-lactic acid (PLLA), poly ( ε- caprolactone) or polyglycolic acid (PGA) And the like, and then spun into a fibrous form. In addition, poly (glycolic acid), poly (DETOSU-1,6 HD-t-CDM ortho ester), poly (DTE carbonate), poly (methyl 2-cyanoacrylate), poly (p-methyl phenoxy) poly (PCPP-SA anhydride) have been developed, and they can be spun into a fibrous form and appropriately selected according to the purpose of use to produce a biodegradable suture for lifting.

Among the above biodegradable polymer materials, PDO is manufactured as a biodegradable suture for lifting, so that it is safe during the operation and less susceptible to foreign matter during the operation. In addition, decomposition usually takes place in the body for 6 months after the procedure.

PLLA is manufactured as a biodegradable suture for lifting, and the disintegration progresses slowly over a period of one to two years in the body during the procedure. However, there is a disadvantage that a foreign body sensation is felt after the procedure.

In addition, PCL is manufactured as a biodegradable suture for lifting, and it takes about 2 years to decompose in the body during the operation. It has a longer duration than other biodegradable polymer materials and it is possible to control the decomposition rate according to the degree of polymerization during synthesis. The PCL hardly senses a foreign object after the procedure, and has a high tensile strength, so that there is little fear that the PCL will be broken during the procedure.

PGA is a biodegradable suture for lifting, and it takes 60 to 90 days to decompose in the body during the procedure. It does not contain collagen protein or antigenic material, and has a small inflammatory reaction and low infection rate .

The biodegradable polymer material of the present invention may be any one selected from the group consisting of PDO, PLLA, PCL, and PGA.

In addition, the biodegradable polymer material in the present invention may be selected from the group consisting of p -dioxanone, glycolide, L-lactide, D-lactide, epsilon -caprolactone (竜 -caprolactone), and trimethylenecabonate. The term " monomers "

In the monofilament manufacturing method of the present invention, after the biodegradable polymer material is melted, the melt is radiated through a spinneret, followed by solidification in a cooling water tank, followed by stretching to produce a monofilament. That is, a hopper to which a biodegradable polymer material is fed, an extrusion processing machine for melting the supplied biodegradable polymer material and extruding the biodegradable polymer material into a yarn-like shape, a cooling section for cooling the extruded yarn, And a guide roller for allowing the drawn yarn to be separated from the yarn and allowing the yarn to be wound around the winding portion without fail by maintaining a predetermined tension so as to be wound on the winding portion without fail. Monofilaments can be produced. Typically, the monofilaments can be produced by spinning the biodegradable polymer material to a thickness of about 1 to 5 deniers. These radiated monofilaments can be subjected to a conventional spraying process or a rewinding process to separate them into individual monofilaments for subsequent processing if necessary.

As shown in FIG. 1, the biodegradable multicomponent multifilament for manufacturing the facial and lifting suture 50 of the present invention is manufactured by stringing or braiding a plurality of the monofilaments. FIG. 1 (a) is a schematic view of a lifting suture 50 made of biodegradable multicomponent multifilament in which eight monofilaments are folded together, and FIG. 3 (b) is a schematic view of a lifting suture 50 in which three monofilaments are bladed biodegradable Fig. 3 is a schematic view of a lifting suture 50 made of a component-based multifilament. That is, the monofilament produced as described above is folded by using a plier. The yarn fitter refers to a device for yarn-joining two or more yarns. At this time, a twist may be given at the time of piling. The blading means a process of orienting the fibers in an oblique direction in a longitudinal direction of a product produced by crossing monofilaments and forming a continuous state without being folded back and cut at the end portions. The blading is performed using a knitting machine. As described above, the multifilament fabricated by folding or braiding monofilaments has the advantage that the tensile force is large and the treatment site is not easily opened due to an external force after the procedure.

Since the folding and blending process is well known in the art, further description thereof will be omitted. However, the biodegradable multicomponent multifilament of the present invention preferably has 2 to 24 monofilaments folded or folded to vary the thickness in various ways. When the monofilaments of three or less strands are folded or blended, the tensile strength of the suture thread is weak, and the strength retention rate after the procedure is rapidly lowered, which may cause side effects to occur. If more than 24 strands are folded or bladed, the thickness of the suture is large, which causes hemorrhage and pain. Therefore, the lifting suture 50 should be changed by changing the thickness of the lifting suture 50 according to the tissue thickness of the treatment site or the condition of the skin. That is, when the thinning skin such as under the eyes and forehead is used Use a silver thread, and use a thick thread for thick skin areas such as face and balls. Therefore, the thickness of the suturing thread 50 for lifting can be determined according to the treatment site, and the thickness of the suture thread can be adjusted by increasing or decreasing the number of the monofilaments to be folded or bladed.

In addition, the lifting suture 50 has different strength retention ratios required depending on the part to be treated. Therefore, a monofilament made of PLLA or PCL is poured or bladed on a site requiring a long-term strength maintenance ratio, and a monofilament made of PGA or PDO is poured or blended in a site requiring a short-term strength maintenance ratio . As described above, the strength retention ratio after the operation of the lifting suture 50 can be appropriately changed by properly folding or blending the monofilament of the polymer material, which takes a long period of time at the time of disassembly, and the monofilament, which takes a short period of time at the time of disassembly. The thickness of the suturing thread for lifting 50 varies depending on the part to be treated. However, considering the depth to the dermis layer and the operation range of the suturing part, the thickness of the biodegradable multi-component multi- The thickness of the filament is preferably 0.03 to 2.0 mm. And the length of the suture may be sufficiently long depending on the scope of the procedure. In the case of lifting the face wrinkles, it is preferably about 20 to 200 mm. In the case of lifting the body wrinkles, it is preferably 50 to 600 mm. In the case of abdomen lifting, 100 to 900 mm is preferable.

The biodegradable multicomponent multifilament of the present invention is prepared by folding or blending a plurality of monofilaments having different biodegradation characteristics as described above and lifting sutures for lifting the face and body using the biodegradable multicomponent multifilament 50) can be manufactured, and a treatment instrument for lifting the face and the body part is manufactured using the same.

Hereinafter, a preferred embodiment of the present invention will be described in detail with reference to the accompanying drawings.

FIG. 2 is a photographic view showing the construction of a facial and body lifting operation device 80 according to an embodiment of the present invention. FIG. 3 is a perspective view illustrating a fixing member 70 for fixing a suture according to an embodiment of the present invention. And FIG. 8 is a photograph showing a facial and body lifting operation device 80 provided.

2 to 3, the facial and body lifting orthodontic appliance 80 of the present invention includes a top end hole 30 formed to be inserted into a lifting suture 50, And a cap end member (40) located at a lower end of the other end and adapted to be engaged with a handle (60) which is held by a practitioner and is easy to perform; A handle 60 which is engaged with the capillary end member 40 and is held by a practitioner and is easy to perform; And a body-lifting suture (50) which is partially inserted into the needle (10) through the upper end hole (30) and partially exposed to the outside of the needle (10) And a fixing member 70 fixed to the cap tube 20 in which the lifting suture 50 is inserted to fix the lifting suture 50 exposed to the outside.

Functions of the respective technical constructions constituting the facial and body lifting operation device 80 of the present invention will be described as follows.

The needle 10 includes a needle cap 20 including a cap top hole 30 formed at an upper end portion of the needle to insert the lifting suture 50 of the present invention, And a wicking end member 40 that allows the operator to engage with a handle 60 that is easy to hold and manipulate. The inner diameter of the needle tube 20 can be appropriately selected from the standardized types. The material of the needle tube end member 40 is most preferably synthetic resin, but it is also possible to use a metal material. The material of the needle 10 Silver is preferred.

In addition, the end portion of the cap tube 20 may have a sharp or rounded shape, but other shapes may be used. The shape of the top end hole 30 is most preferably a circular shape, but a polygonal shape such as an elliptical shape, a square shape, a diamond shape, a trapezoid shape, or the like is also possible.

The handle 60 is coupled with the capillary end member 40 so that a practitioner can hold the cap 60 easily. Here, the material of the handle 60 is most preferably synthetic resin, but it is also possible to use a metal material.

The lifting suture 50 is inserted into the cap top hole 30 and inserted into the cap tube 20 formed inside the needle 10. A part of the lifting suture 50 is inserted into the needle 10 through the top end opening 30 and the part of the lifting suture is exposed to the outside of the needle 10, A facial and body lifting treatment instrument is completed. 2 is a photographic view of a lifting suture 50 of the present invention partially inserted into a needle and a portion of which is exposed to the outside of the needle, and a surgical instrument for lifting the body. Here, the lifting suture 50 has a straight shape or a twisted shape by a folding or blading process.

As described above, the present invention provides a suturing device for facial and body lifting (50) and a surgical instrument capable of arbitrarily adjusting the biodegradation characteristics and the strength maintenance ratio at the time of operation according to the biodegradable polymer. In addition, since the present invention is manufactured by folding or blending a plurality of monofilaments, it is possible to make both a straight shape and a twisted shape, and it is possible to control the thickness of the suture so that the pain and the number of procedures are reduced, A suture 50 for body and lifting that can be applied to the face and the body, and a treatment instrument.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it will be understood by those of ordinary skill in the art that various changes in form and details may be made therein without departing from the scope of the present invention. Accordingly, the true scope of the present invention should be determined by the technical idea of the appended claims.

10: needle, 20: piercing, 30: hole, 40: piercing end member, 50: lifting suture, 70: fixing member, 80: face and body lifting

Claims (8)

Biodegradable multicomponent multifilament for making sutures 50 for facial and body lifting,
A plurality of biodegradable polymeric materials having different biodegradation rates, wherein the monofilaments selected from the group consisting of polydioxanone, polycaprolactone, and polyhydroxybutyrate are combined or bladed ≪ / RTI >
The thickness of the monofilament is 1 to 500 denier, the thickness of the biodegradable multicomponent multifilament is 0.03 to 2.0 mm,
Wherein the monofilament is 2 to 24 strands and has a length of 20 to 900 mm;
And a biodegradable multi-component multifilament.
delete Biodegradable multicomponent multifilament for making sutures 50 for facial and body lifting,
As biodegradable plural biodegradable polymer material different speeds, para- the lactide (D -lactide) and trimethylene one or more monomers selected from the group consisting of carbonate (trimethylenecabonate) - dioxanone (p -dioxanone), di The monofilaments prepared by copolymerization are prepared by folding or blending,
The thickness of the monofilament is 1 to 500 denier, the thickness of the biodegradable multicomponent multifilament is 0.03 to 2.0 mm,
Wherein the monofilament is 2 to 24 strands and has a length of 20 to 900 mm;
And a biodegradable multi-component multifilament.
delete The method according to claim 1 or 3,
Wherein said twisted monofilament is further provided with a twist. ≪ RTI ID = 0.0 > 8. < / RTI &
delete A suture (50) for face and body lifting,
The suture (50) for facial and body lifting, which is composed of the biodegradable multicomponent multifilament of claim 1 or claim 3,

delete

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