KR101923595B1 - Coating device and mothod for wire electrode manufacturing - Google Patents

Abstract

The present invention relates to a method for producing a silver electrode, which is capable of continuously forming a reference electrode located on a substrate such as a wire or tube sensor used as a subcutaneous sensor at a predetermined interval, The present invention relates to a silver resin coating apparatus and a coating method for a reference electrode which can be coated in consideration of position.
The present invention comprises a pair of coating modules disposed on both sides of a wire-like substrate, and a silver resin supply module for supplying silver resin to the coating module, wherein the coating module comprises a coating module body, And a silver resin supply unit for supplying the silver resin from the silver resin supply module.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a coating solution for a reference electrode of a subcutaneous sensor,

The present invention relates to a method for manufacturing a silver-based sensor, which comprises the steps of: preparing a silver resin on a substrate continuously supplied with a reference electrode used for a wire-type or tube-type sensor used as a subcutaneous sensor, And more particularly to a silver resin coating apparatus and a coating method for a reference electrode which can be coated.

In general, a silver / silver chloride electrode is often used as a reference electrode for a subcutaneous sensor, such as an electrocardiogram, a PH meter, a dissolved oxygen electrode, and a glucose sensor. This is because the biological fluid contains 0.15 moles of salt and a very small amount of potassium chloride in a considerable amount of chloride ion, for example, human blood, so that the analyte in the biological system can be electrochemically measured by using the potential difference between the chloride ion and silver / It is because.

In the case of a tubular sensor, such a reference electrode is formed by forming a conductive layer on a base layer, coating an insulating film thereon, and etching an insulating film at a predetermined position to expose a part of the conductive layer to the outside so that the exposed conductive layer can be used as an electrode . In the case of a wire type sensor, since the wire itself is a conductor, it is manufactured so that the exposed wire can be used as a working electrode by etching the insulating layer and the silver coated wire at a predetermined interval after coating the insulating layer on the substrate layer.

As a method of etching the insulating film, various methods such as a method of exposing and removing by using a photosensitive resin, a method of etching using a laser, and other dry or wet methods have been proposed. However, Shape, size, and position, it is difficult to mass-produce continuously, and there is a problem that remnants remain.

In addition, due to the residues, the thickness and the area of the reference electrode are not uniform and the reference electrode and the working electrode are insulated, but there is a possibility that the electrical connection is made.

Korean Patent Registration No. 0135367 (registered on Jan. 13, 1998) Japanese Patent Publication No. 1985-201245

SUMMARY OF THE INVENTION The present invention has been made in order to solve the above-mentioned problems, and it is an object of the present invention to provide a reference electrode for use in a wire type or tube type sensor used as a subcutaneous sensor, And a method of coating a silver resin for a reference electrode capable of coating a silver resin continuously supplied on a surface of a substrate in consideration of a predetermined electrode shape, size, and position.

In order to accomplish the above object, according to one aspect of the present invention, there is provided a silver / silver chloride coating apparatus for a reference electrode of a subcutaneous sensor, comprising: a pair of coating modules disposed on both sides of a wire- And a silver resin supply module for supplying silver resin to the wire-shaped base material, wherein the coating module comprises a coating module body, a coating part for contacting the wire-shaped base material to coat the wire-like base material with silver resin, And a silver resin supply portion to which silver resin is supplied.

In addition, the silver / silver chloride coating device for a reference electrode of the subcutaneous sensor may include a control unit, and the control unit may control the longitudinal movement of the coating unit with respect to the coating module, And may include a separation control function.

In addition, the silver / silver chloride coating device for a reference electrode of the subcutaneous sensor may include a control function of longitudinal movement of the wire-like base material in the longitudinal direction.

In addition, silver / silver chloride coating device for reference electrode of the subcutaneous sensor may be configured such that the body of the coating module is formed of elastic silicone or polyurethane material, and the coating part is recessed in the coating module body, May be provided as at least one or more input ports communicating with the silver resin supply module and passing through the coating module body.

Further, in the silver / silver chloride coating device for a reference electrode of the subcutaneous sensor, the width of the coating portion may be 2.5 times or more of the width of the charging port.

In addition, the silver / silver chloride coating device for a reference electrode of the subcutaneous sensor may be configured such that the control unit adjusts the moving speed of the coating unit in the longitudinal direction of the coating unit by 0.01 cm / s, Can be adjusted in units of 0.01 cm, and the bonding speed or separation speed of the coating module can be adjusted in units of 0.01 cm / s.

In addition, the silver / silver chloride coating device for a reference electrode of the subcutaneous sensor may include an injector having a needle capable of supplying silver resin in a droplet form and capable of providing a silver resin in a predetermined amount, And may include a syringe pump that applies a constant pressure.

In addition, the silver / silver chloride coating device for a reference electrode of the subcutaneous sensor may include a position sensor for confirming the position of the wire-like base material.

Meanwhile, the silver / silver chloride coating method for a reference electrode of a subcutaneous sensor according to an aspect of the present invention includes a wire-type substrate fixing step, a silver resin application amount setting step, a coating module movement setting step, and a pair of coating module disposing steps .

In addition, the silver / silver chloride coating method for the reference electrode of the subcutaneous sensor may include the step of setting the number of repetitions, performing the coating step, moving the wire-shaped substrate, and initializing the coating module.

According to an embodiment of the present invention, a silver resin that is continuously supplied on a substrate so that reference electrodes used in a wire-type or tube-type sensor used as a subcutaneous sensor or the like may be discontinuously formed at a predetermined interval, Size, and position of the reference electrode, and a coating method for the reference electrode.

It is possible to provide a silver resin coating apparatus and a coating method for a reference electrode which can remove a process of etching a predetermined gap of an insulating film and a silver coated wire.

Also, there is provided a silver resin coating apparatus for a reference electrode and a coating method capable of mass-producing a wire electrode used for an in-vivo analyte measurement sensor or the like in a short time and easily adjusting the shape, size, and position of the wire electrode .

Particularly, according to one embodiment of the present invention, it is possible to provide a silver resin coating apparatus and a coating method for a reference electrode, which achieve a technical effect such that a silver resin does not aggregate and a coating section is neatly dropped when attaching and detaching a coating module.

1 is a perspective view schematically illustrating a coating module of a silver / silver chloride coating apparatus for a reference electrode of a subcutaneous sensor according to an embodiment of the present invention.
Fig. 2 is a view showing the technical construction of the silver resin supply module.
3 is a view schematically showing a silver / silver chloride coating apparatus for a reference electrode of a subcutaneous sensor including a control unit.
4 is a view showing a process in which a coating module is operated by a control unit to perform silver / silver chloride coating on a wire-shaped substrate
5 is a view for explaining a silver / silver chloride coating method for a reference electrode of a subcutaneous sensor.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings so that those skilled in the art can easily carry out the present invention. The present invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. In order to clearly illustrate the present invention in the drawings, parts not related to the description are omitted, and like parts are denoted by similar reference numerals as the serial numbers throughout the specification.

Throughout the specification, when an element is referred to as "comprising ", it means that it can include other elements as well, without excluding other elements unless specifically stated otherwise. Also, the terms "part," "module," and the like, which are described in the specification, refer to a unit for processing at least one function or operation, and may be implemented by hardware or software or a combination of hardware and software.

Hereinafter, a silver / silver chloride coating apparatus for a reference electrode of a subcutaneous sensor according to an embodiment of the present invention will be described in detail with reference to the accompanying drawings.

FIG. 1 is a perspective view schematically showing a coating module of a silver / silver chloride coating device for reference electrodes of a subcutaneous sensor according to an embodiment of the present invention, and FIG. 2 is a view showing a technical configuration of a silver resin supply module.

A silver / silver chloride coating device for a reference electrode of a subcutaneous sensor according to an embodiment of the present invention includes a pair of coating modules 100 and a silver resin supply module 200.

The coating module 100 is provided such that two pairs of symmetrical shapes are paired so that a wire-like substrate is disposed between the two coating modules 100, and a pair of the coating modules 100 are combined and moved, Can be formed.

The coating module 100 includes a coating module body 120, a coating portion 140, and a silver resin supply portion 160.

The coating module body 120 is a portion where the width of the wire-shaped substrate coated on the coating module 100 is determined, and can be formed into a shape that can be directly coupled to the entire coating apparatus. The coating module body 120 may be provided in various shapes according to a method of being coupled to a coating apparatus. In FIG. 1, the coating module body 120 has a vertically long rectangular parallelepiped shape as an example.

The coating module body 120 is preferably made of, for example, a silicon-based or polyurethane material that is elastic and can not absorb an organic solvent. The coating module body 120 may be formed of a wire- Stretch on both sides for uniform and thin silver resin coating.

The coating module body 120 can be attached or detached directly to the silver / silver chloride coating device for the reference electrode of the subcutaneous sensor, and can be detached, washed and reused. When the coating module 100 includes the fixing portion 180 described below, the coating module body 120 may be provided to be attachable or detachable to the fixing portion 180, And can be reused after cleaning.

A coating portion 140 may be provided on the coating module body 120. The coating portion 140 may contact the wire-shaped substrate to coat silver / silver chloride. The coating portion 140 may be provided in a concave shape in the coating module body 120 to more effectively perform the function of elastically pressing the wire-like base material on both sides.

The coating portion 140 functions to fix the wire-shaped substrate, and when the wire-shaped substrate is fixed by the coating portion 140, the thickness can be uniformly coated. The coating portion 140 is provided to have a thin width so that the coated cross section of the wire-like substrate is neat, and may be formed with a width of preferably about 3 to 5 mm.

The coating portion 140 formed in each coating module 100 may be provided in a shape similar to a semicircular or semicircular cross-section so as to have a shape surrounding the wire-like base material when a pair of the coating modules 100 are combined. Since the diameter of the wire-shaped substrate used is typically 150 to 300 μm, the coated portion 140 in a state where a pair of the coating modules 100 are coupled surrounds the wire-shaped substrate having the diameter, It is preferable that the coating portion 140 is provided at a certain diameter.

A silver resin supply part 160 is formed in the coating module body 120. The silver resin supplied from the silver resin supply module 200 by the silver resin supply part 160 may be transferred to the coating part 140. [ The silver resin supply part 160 may be provided as a slot or a hole through which the coating module body 120 including the coating part 140 passes. When the silver resin supply part 160 is provided as a charging port, the coating part 140 is formed to have a width of at least 2.5 times the width of the charging port, which is preferable because the coated surface of the wire-like base material is more clean.

The silver resin supply part 160 may be formed in the shape of one or more tubes or holes along the coating part 140 and preferably disposed at the center when only one tube or hole is formed so that the silver resin does not cohere with one place And when two or more tubes or holes are formed, they are preferably spaced apart at a predetermined interval.

The fixing portion 180 may be included in the coating module 100. The fixation portion 180 may be attached to the coating module body 120 to perform the function of bonding the silver / silver chloride coating device for the reference electrode of the subcutaneous sensor.

In addition, the coating module 100 may include a position sensor (not shown) that can identify the position of the wire-like substrate when the pair of coating modules 100 are coupled.

The silver resin supply module 200 supplies silver resin to the coating module 100. The silver resin supply module 200 includes a syringe pump 210 and an injector 230.

The timing at which the silver resin supply module 200 supplies the silver resin to the coating module 100 may be specified. The silver resin supply module 200 is moved to the coating module 100 at a time when the movement of the coating module 100 is temporarily stopped, that is, when a pair of the coating modules 100 is maximally separated or when a pair of the coating modules 100 are coupled 100). ≪ / RTI > When the silver resin is supplied at a time when the movement of the coating module 100 is temporarily stopped, the characteristics such as the quantity of silver resin and the flow rate supplied by the silver resin supply module 200 can be adjusted more precisely.

The injector 230 may have a needle 232 for supplying silver resin in a droplet form. When the silver resin is supplied in a droplet form by the needle 232, the silver resin to be injected can be adjusted to a fine unit.

The injector 230 may include a pressure bar 234 which applies pressure to the inside so that the silver resin can be supplied to the coating module 100.

The silver resin passes from the injector 230 through the needle 232 and through the silver resin supply portion 160 of the coating module 100 to the coating portion 140). Alternatively, the silver resin may be supplied to the coating portion 140 through the hose 220 passing through the needle 232 from the injector 230 and communicating with the silver resin supply portion 160 of the coating module 100.

The syringe pump 210 may apply pressure to the injector 230. When the syringe pump 210 applies a predetermined pressure to the injector 230, the silver resin may be supplied to the coating module 100 in a predetermined amount per unit time. When the syringe pump 230 is provided with the pressure pedestal 234, the syringe pump 210 can pressurize the pressure pedestal 234 by applying a force thereto.

The pressure applied by the syringe pump 210 to the injector 230 may be set in an automatic manner. In order to automatically set the pressure of the syringe pump 210 as described above, the silver resin supply module 200 may include a screen portion 250, an input portion 270, and an automatic adjustment device (not shown).

FIG. 3 is a schematic view illustrating a silver / silver chloride coating apparatus for a reference electrode of a subcutaneous sensor according to an embodiment of the present invention. FIG. 4 is a cross- Fig. 3 is a view showing a process of being operated by the control unit. Fig.

The controller 300 may control the movement of the coating module 100. More specifically, the control unit 300 controls the back and forth movement in the longitudinal direction (the X-axis direction in FIG. 4) of the wire-shaped base material and the control in the direction orthogonal to the longitudinal direction of the wire- , It is possible to perform a control to couple a pair of coating modules 100 so as to fix the wire-like base material and to separate a pair of coating modules 100 from the wire-shaped base material.

The controller 300 may be provided separately from the coating module 100. Alternatively, the controller 300 may be coupled to the coating module 100 to directly control the coating module 100. When the control unit 300 is included in the coating module 100, the control unit 300 may be provided inside the fixing unit 180. An operation unit (not shown) may be provided in the control unit 300 for presetting for automatic control.

The control unit 300 is preferably provided to control the X axis movement speed, the coating area / non-coating area movement distance, and the coupling / separation speed of a pair of the coating module 100 in a fine unit.

In the silver / silver chloride coating apparatus for reference electrode of the subcutaneous sensor according to an embodiment of the present invention, an experiment was conducted to determine the width of a suitable coating portion 140 and the separation speed of a pair of coating modules 100. The following table summarizes the results of 100 experiments in which the width of the coating portion 140 and the separation speed of a pair of the coating module 100 are different for a wire-shaped substrate having a diameter of 150 μm.

Size of width
3 to 5 mm
5 to 7 mm
7 ~ 10mm
Speed of separation
Slow
speed
Slow
speed
Slow
speed
Aggregation unit
Three
30
5
50
6
70

<Table 1: Coating width / coating module separation speed and aggregation unit>

In light of the above experiment, it is preferable that the width of the coating portion 140 is 3 to 5 mm as described above. It is preferable that the separation speed of the pair of coating modules 100 is small so that the slower the separation rate is, the more appropriate is provided in consideration of the working environment and the coating speed with respect to the wire-shaped substrate. More specifically, it is preferable that the control unit 300 is provided to set a coupling or separation speed of a pair of coating modules 100 in units of 0.01 cm / s. The controller 300 can control the movement speed of the pair of X-axis of the coating module 100 to 0.01 cm / s and the moving distance of the coating areas I and III / uncoated areas II and IV to 0.01 cm / It is desirable to provide controllable units.

In the wire-like substrate, it is preferable that a coating region coated with silver / silver chloride and an uncoated region coated with silver / chloride chloride are alternately formed.

After the wire-shaped substrate is fixed by a separate device, a pair of coating modules 100 are symmetrically disposed about the fixed wire-shaped substrate. When the silver / silver chloride coating device for a reference electrode of the subcutaneous sensor according to an embodiment of the present invention is operated, a pair of coating modules 100 are moved in the Y and -Y directions by the control part 300 The wire-shaped substrate is held in contact with both sides of the coating portion 140 of the coating module 100 and fixed.

The controller 300 moves the pair of the coating modules 100 in the X axis direction while the wire type base material is fixed by the pair of the coating modules 100. As a result, The wire-shaped substrate is coated with the supplied silver / silver chloride, and this region becomes the coating region (I)

At some point, the controller 300 separates a pair of coupled coating modules 100 (shown as B in FIG. 4) and moves a pair of separated coating modules 100 along the X axis. When the pair of coating modules 100 are separated as described above and moved in the X-axis, the non-coated region II appears in the corresponding wire-shaped substrate.

In this manner, the coupling and separation control of a pair of coating modules 100 by the control unit 300 and the movement control in the X-axis direction are repeated (shown as C and D in FIG. 5) The uncoated region IV is implemented and this process can be performed until it reaches the opposite fixing point of the wire-like substrate, so that the coating region and the non-coating region are alternately displayed on the wire-like substrate.

5 is a view illustrating a silver / silver chloride coating method for a reference electrode of a subcutaneous sensor according to an embodiment of the present invention.

The silver / silver chloride coating method for a reference electrode of a subcutaneous sensor according to an embodiment of the present invention includes a step (S10) of fixing a wire-like base material so that the wire-like base material unfolds only in an uncoated region in the X-axis direction. The wire-shaped substrate may be fixed by a separate fixing device.

And a silver resin application amount setting step (S20). The silver resin application amount setting step S20 may be performed by setting the pressure applied to the injector 230 by the syringe pump 210 of the silver resin supply module 200. [ The pressure exerted by the syringe pump 210 may be set by the screen 250 and the input unit 270.

And a coating module movement setting step (S30). The movement of the coating module 100 can be set through the control unit 300. [ In the coating module movement setting step (S30), the X axis moving speed, the coating area / uncoated area moving distance, and the joining / separating speed can be respectively set. The X-axis moving speed and the coupling / separation speed can be set in units of 0.01 cm / s, and the coating area / non-coating area moving distance can be set in units of 0.01 cm.

And a step S40 of placing a pair of the coating modules 100 with the fixed wire-shaped base material interposed therebetween. A pair of coating module placement step S40 includes a pair of coating modules 100 moving to the A position in FIG. A pair of coating module placement step S40 may be performed by the control unit 300. [

After the silver / silver chloride coating method for the reference electrode of the subcutaneous sensor is performed by the wire-type substrate fixing step (S10) to the pair of coating module disposing step (S40), when silver / silver chloride coating device for reference electrode of the subcutaneous sensor is operated, (A wire-shaped base material having a length that can be fixed to the apparatus) is fixed. After completion of the coating of the unit of the fixed wire type substrate, the silver / silver chloride coating method for the reference electrode of the subcutaneous sensor is repeated, starting from the wire-type substrate fixing step (S10) of fixing the wire-shaped base unit to the apparatus (Repetition of steps included in the dashed box in Fig. 5).

The silver / silver chloride coating method for the reference electrode of the subcutaneous sensor can be continuously and repeatedly performed by coating silver / silver chloride on the wire-shaped substrate, and this repetition process can be realized through the step of setting the number of repetitions (S50). If the number-of-repetition setting step S50 is included, the steps S10 to S40 may be executed as a step before the number-of-repetition setting step S50.

If the number-of-repetition setting step S50 is included, the wire-type substrate moving step S60 may be included in the silver / silver chloride coating method for reference electrodes of the subcutaneous sensor. The silver / silver chloride coating method for the reference electrode of the subcutaneous sensor, which includes the step of setting the number of repetitions (S50), is a step of inserting the silver / silver chloride coating for the reference electrode of the subcutaneous sensor Shaped wire base material is preferably provided to the silver / silver chloride coating device for reference electrodes of the subcutaneous sensor and fixed to the wire-like base material fixing device.

A coating execution step (S60) is included. The coating execution step (S60) is performed by a process in which a pair of coating modules (100) move along the X axis while repeating the joining / separating, and this process can be performed by the control unit (300).

The wire-shaped base material moving step S70 proceeds after the coating executing step S60. In the wire-type substrate moving step S70, the wire-shaped substrate in the area where the silver / silver chloride coating method for the reference electrode of the subcutaneous sensor is performed is moved forward by the coating module 100, and the wire- For the reference electrode / silver chloride coating device. The wire-type base material moving step S70 may be performed by the control unit 300. [

When the movement of the wire-shaped base material is completed, the coating module initialization step (S80) is executed. The coating module initialization step S80 moves and binds a pair of coating modules 100 to position A in Fig. 4 as a step corresponding to a pair of coating module placement step S40 in the automated process. The last step of the coating module initializing step S80 may be omitted or only the process of moving the coating module 100 to the position A in FIG. 4 may be performed according to the number of repetition times set in the repetition number setting step S50 can do.

The coating execution step (S60) to the coating module initialization step (S80) may be repeated according to the repetition number set in the repetition number setting step (S50).

The wire coated with the silver / silver chloride coating method for the reference electrode of the subcutaneous sensor may comprise a drying step. The drying step may be a process of desorbing the coated wire from the silver / silver chloride coating device for the reference electrode while being fixed to the fixing device, moving the coated wire to the drying process chamber, and drying the coated wire at room temperature for 3 to 5 hours.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, but, on the contrary, And it goes without saying that the invention belongs to the scope of the invention.

100: coating module 120: coating module body
140: Coating section 160: Silver resin supply section
180: Fixing part 200: Silver resin supply module
210: Syringe pump 220: Hose
230 injector 232 needle
234: pressure band 250:
270: input unit 300:

Claims (10)

A pair of coating modules disposed on both sides of the wire-shaped substrate, and
A silver resin supply module for supplying silver resin to the coating module,
The coating module
Coating module body,
A coating part for contacting the wire-like base material to coat the wire-like base material with silver resin,
A silver resin supply portion to which silver resin is supplied from the silver resin supply module,
And a control unit,
The control unit
A control function of longitudinal movement of the coating portion with respect to the coating module, and
A coupling and separation control function for a pair of said coating modules
Silver / silver chloride coating device for reference electrode of subcutaneous sensor. delete The method according to claim 1,
The control unit
And a control function of longitudinal movement of the wire-like base material in the longitudinal direction
Silver / silver chloride coating device for reference electrode of subcutaneous sensor. The method according to claim 1,
The coating module body is formed of elastic silicone or polyurethane material,
Wherein the coating portion is recessed in the coating module body,
Wherein the silver resin supply unit is provided with at least one or more input ports communicating with the silver resin supply module and passing through the coating module body
Silver / silver chloride coating device for reference electrode of subcutaneous sensor. 5. The method of claim 4,
The width of the coating portion is formed to be 2.5 times or more of the width of the inlet port
Silver / silver chloride coating device for reference electrode of subcutaneous sensor. The method according to claim 1,
The control unit
The longitudinal movement speed of the coating portion of the coating module is adjustable in units of 0.01 cm / s,
The length of the coating module in the longitudinal direction of the coating module can be adjusted in units of 0.01 cm,
The coating speed of the coating module or the separation speed of the coating module can be adjusted in units of 0.01 cm / s
Silver / silver chloride coating device for reference electrode of subcutaneous sensor. The method according to claim 1,
The silver resin supply module
An injector provided with a needle capable of supplying silver resin in a droplet form and capable of providing a silver resin in a predetermined amount, and
And a syringe pump for applying a predetermined pressure to the injector
Silver / silver chloride coating device for reference electrode of subcutaneous sensor. The method according to claim 1,
The coating module
And a position sensor for confirming the position of the wire-like base material
Silver / silver chloride coating device for reference electrode of subcutaneous sensor. A wire-shaped substrate fixing step,
Silver resin application amount setting step,
A coating module movement setting step,
A pair of coating module placement steps;
Controlling longitudinal longitudinal movement of the coating portion relative to the coating module and coupling and separation of the coating module pair
Silver / silver chloride coating method for reference electrode of subcutaneous sensor. 10. The method of claim 9,
A repetition number setting step,
Coating execution step,
A wire-type substrate moving step, and
Comprising a coating module initialization step
Silver / silver chloride coating method for reference electrode of subcutaneous sensor.

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