KR101902078B1 - Blood Sugar Detector Charging based on ATP - Google Patents

Blood Sugar Detector Charging based on ATP Download PDF

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KR101902078B1
KR101902078B1 KR1020160169228A KR20160169228A KR101902078B1 KR 101902078 B1 KR101902078 B1 KR 101902078B1 KR 1020160169228 A KR1020160169228 A KR 1020160169228A KR 20160169228 A KR20160169228 A KR 20160169228A KR 101902078 B1 KR101902078 B1 KR 101902078B1
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South Korea
Prior art keywords
blood glucose
bio
atp
battery module
electric energy
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KR1020160169228A
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Korean (ko)
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KR20180067853A (en
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박준후
박동휘
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(재)대구포교성베네딕도수녀회
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Priority to KR1020160169228A priority Critical patent/KR101902078B1/en
Priority to PCT/KR2016/015345 priority patent/WO2018110756A1/en
Publication of KR20180067853A publication Critical patent/KR20180067853A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue

Abstract

An ATP-based blood glucose meter is provided. An ATP-based blood glucose meter according to an embodiment of the present invention includes a blood glucose measurement module inserted into the body and measuring blood glucose, and inserted into the body to produce electric energy based on a substance in the body, And a bio-battery module for supplying the bio-cell to the measurement module.

Description

BACKGROUND ART Adenosine triphosphate (ATP) -based blood glucose system {Blood Sugar Detector Charging based on ATP}

The present invention relates to an ATP (Adenosine Triphosphate) -based blood glucose meter. More specifically, the present invention relates to a blood glucose meter that provides a blood glucose meter to be inserted into the body, and utilizes ATP in the body as an electric energy source for driving the blood glucose meter.

Diabetes mellitus, which represents a typical adult disease, currently affects about 5% of the total population, and the incidence is gradually increasing. In particular, diabetes is a chronic disease that can not be cured if it is invented once, so self-management is absolutely necessary.

In this case, self-management refers to the daily measurement of blood glucose and the management of blood glucose by the blood drawn from the fingertips of a diabetic patient himself / herself using a blood glucose meter every day, which changes according to food intake, activity level, drug or insulin therapy.

Blood glucose measurement by blood sampling is called invasive blood glucose measurement. In the case of invasive blood glucose measurement, glucose oxidase is applied to the end of strip and glucose is measured by enzyme reaction. In other words, when blood is taken from a finger or the like, and the enzyme is brought into contact with a fixed strip, blood glucose reacts with the enzyme.

However, the invasive blood glucose measurement method has disadvantages in that blood glucose measurement is absolutely irrelevant according to the necessity of blood collection process, change of blood collection site, and proficiency of blood collection method. And fundamentally, there is great difficulty in accurately measuring changes in blood glucose concentration by non-continuous measurements. There is also a disadvantage that it is extremely difficult to measure blood sugar during sleeping time.

In recent years, studies on an intubating blood glucose sensor have been conducted. However, the invasive blood glucose sensor had to have a limited life due to the limitation of the battery capacity of the sensor.

Therefore, the inventors of the present invention have invented a blood glucose meter capable of permanently driving blood glucose meter once it has been inserted into the body without replacing the battery.

Disclosure of Invention Technical Problem [8] Accordingly, the present invention provides a blood glucose meter that provides an intramuscular blood glucose meter and utilizes ATP in the body as a power source.

Another technical problem to be solved by the present invention is to provide a blood glucose meter which forcibly drains blood glucose when the body has high blood sugar.

The technical problem to be solved by the present invention is not limited to the above.

In order to solve the above technical problems, the present invention provides an ATP-based blood glucose meter.

An ATP-based blood glucose meter according to an embodiment of the present invention includes a blood glucose measurement module inserted into the body and measuring blood glucose, and inserted into the body to produce electric energy based on a substance in the body, And a bio-battery module for supplying the bio-cell to the measurement module.

According to one embodiment, the bio-battery module includes an anode formed with an enzyme, an electrolyte, and a cathode electrode. When the substance in the body is glucose and ATP, the enzyme is glucose-6-phosphato dihydro It can be crab nemesis.

According to an embodiment, the anode electrode may generate NADH through the enzyme, and oxidize the generated NADH to produce the electrical energy.

According to one embodiment, when the substance in the body contains ATP, the blood glucose measurement module can measure the amount of blood glucose in the body based on the amount of electric energy generated from the substance in the body per unit time.

According to one embodiment, the blood glucose measurement module can measure the blood glucose level based on the difference in impedance.

According to an embodiment of the present invention, there is provided a blood glucose measurement module, further comprising a controller for controlling at least one of the blood glucose measurement module and the bio-battery module, wherein when the measured blood glucose level of the body is equal to or higher than a reference value, The blood sugar amount can be reduced.

According to an embodiment of the present invention, there is further provided a control unit for controlling at least one of the blood glucose measurement module and the bio-battery module, wherein the control unit changes the blood glucose measurement method based on the amount of electric energy stored in the bio- .

An ATP-based blood glucose meter according to an embodiment of the present invention includes a blood glucose measurement module inserted into the body for measuring blood glucose and inserted into the body to supply electric energy to the blood glucose measurement module, And a bio-battery module for supplying the blood glucose measurement module to the blood glucose measurement module.

According to an embodiment of the present invention, since the self-filling can be performed based on the substance in the body, the ease of use of the intramuscular blood glucose meter can be improved.

1 is a view for explaining a usage environment of an ATP-based blood glucose meter according to an embodiment of the present invention.
Figure 2 shows a block diagram of an ATP-based blood glucose meter according to an embodiment of the present invention.
3 is a diagram for explaining conversion of ATP and ADP.
4 is a view for explaining a bioenergy module according to an embodiment of the present invention.
5 is a view for explaining an example of driving an ATP-based blood glucose meter according to an embodiment of the present invention.
6 is a view for explaining another driving example of an ATP-based blood glucose meter according to an embodiment of the present invention.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. However, the technical spirit of the present invention is not limited to the embodiments described herein but may be embodied in other forms. Rather, the embodiments disclosed herein are provided so that the disclosure can be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.

In this specification, when an element is referred to as being on another element, it may be directly formed on another element, or a third element may be interposed therebetween. Also, in the drawings, the shape and shape are exaggerated for an effective description of the technical content.

Also, while the terms first, second, third, etc. in the various embodiments of the present disclosure are used to describe various components, these components should not be limited by these terms. These terms have only been used to distinguish one component from another. Thus, what is referred to as a first component in any one embodiment may be referred to as a second component in another embodiment. Each embodiment described and exemplified herein also includes its complementary embodiment. Also, in this specification, 'and / or' are used to include at least one of the front and rear components.

The singular forms "a", "an", and "the" include plural referents unless the context clearly dictates otherwise. It is also to be understood that the terms such as " comprises "or" having "are intended to specify the presence of stated features, integers, Should not be understood to exclude the presence or addition of one or more other elements, elements, or combinations thereof. Also, in this specification, the term "connection " is used to include both indirectly connecting and directly connecting a plurality of components.

In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear.

An ATP-based blood glucose meter (hereinafter referred to as a blood glucose meter) according to an embodiment of the present invention can be inserted into the body to measure blood glucose in the body. At this time, the blood sugar system can be an energy source in the body, for example, ATP, which is an energy storage unit in the body. Accordingly, once the blood glucose meter according to an embodiment of the present invention is inserted into the body, the blood glucose can be permanently measured without having to replace the battery separately. Hereinafter, a description will be given with reference to the drawings.

FIG. 1 is a view for explaining a usage environment of an ATP-based blood glucose meter according to an embodiment of the present invention, and FIG. 2 is a block diagram of an ATP-based blood glucose meter according to an embodiment of the present invention.

ATP-based blood glucose system environment

Referring to FIG. 1, the blood glucose meter 100 according to an embodiment of the present invention may be inserted into a part of a body. The insertion position of the blood glucose meter 100 may vary. ATP can be produced in the mitochondria in the cell, particularly in muscle cells. Therefore, the blood glucose meter 100 can be inserted into the muscle region. In addition, ATP can migrate along the blood vessels. Therefore, the blood glucose meter 100 can be inserted at a position where blood flow is easy, insertion is easy, and body motion is not affected. For example, the blood glucose meter 100 may be inserted into the back of the hand or inside the arm.

The blood glucose meter 100 according to an embodiment of the present invention can communicate with the external electronic device 300. For example, the blood glucose meter 100 may receive a command, e.g., a blood glucose meter control command, from the external electronic device 300 and operate accordingly. In addition, the blood glucose meter 100 may provide the blood glucose measurement result to the external electronic device 300. The blood glucose meter 100 may transmit information on an operation status of the blood glucose meter 100 to the external electronic device 300, for example. Hereinafter, referring to FIG. 2, the blood glucose meter 100 according to an embodiment of the present invention will be described in more detail.

ATP-based blood glucose meter (100)

2, the blood glucose meter 100 according to an exemplary embodiment of the present invention includes at least one of a blood glucose measurement module 110, a bio-battery module 120, a communication unit 140, and a controller 150 . In this case, the blood glucose measurement module 110 and the bio-battery module 120 may be separate components, but the blood glucose measurement module 110 and the bio-battery module 120 may be integrally configured .

The blood glucose measurement module (110)

The blood glucose measurement module 110 performs a sensor function for measuring blood glucose in the body, and can measure blood glucose in various ways.

For example, the blood glucose measurement module 110 may measure blood glucose based on the impedance difference. More specifically, a very small change in blood glucose concentration leads to a decrease in sodium ion in red blood cells and an increase in potassium ion, and to induce a cell membrane reaction. The specific reaction between blood and tissue cells is altered by blood sugar, so the electrolyte balance across the cell membrane changes, resulting in changes in membrane permeability, conductivity, and junction polarization (Maxwell-Wagner effect). That is, changes in blood sugar change the dielectric properties of the skin and subcutaneous tissue, resulting in changes in the dielectric spectrum that can be measured by impedance. Although glucose itself does not affect the dielectric spectrum present in the MHz band, it can instead use impedance spectroscopy to convert the series of changes into glucose levels.

For example, the blood glucose measurement module 110 may measure blood glucose through the tissue fluid around the blood glucose measurement module 110.

In another example, the blood glucose measurement module 110 may measure blood glucose based on the amount of electric energy generated from ATP. More specifically, the blood glucose measurement module 110 can measure blood glucose based on the amount of electric energy generated from ATP per unit time. In this case, the blood glucose measurement module 110 may be integrated with the bio-battery module 120 to be described later.

The bio-

The bio-battery module 120 may be inserted into the body and supply electric energy to the blood glucose measurement module 110. For this purpose, the bio-battery module 120 can supply electric energy to the production, storage and blood glucose measurement module 110 based on the ATP in the body. The bio-battery module 120 will be described in detail with reference to FIGS. 3 and 4. FIG.

The communication unit 140,

The communication unit 140 may perform a function of communicating with the external electronic device 300. As described above, the communication unit 140 may transmit information on the blood glucose meter 100 operation status and / or blood glucose measurement result to the external electronic device 300. Also, the communication unit 140 can receive a signal, for example, a command signal from the external electronic device 300. The communication unit 140 may provide the received command signal to the controller 150 to be described later. The communication unit 140 may include at least one of Bluetooth, Radio Frequency Identification (RFID), infrared data association (IrDA), UltraWideband (UWB), and ZigBee.

The controller 150,

The controller 150 may control the blood glucose meter 100 as a whole. For example, the controller 150 may periodically or non-periodically measure the blood glucose level through the blood glucose measurement module 110. The controller 150 may store the blood glucose measurement results in a database. The controller 150 may receive the necessary electrical energy through the bio-battery module 120. [ The control unit 150 may instruct the bio-battery module 120 to generate and store electrical energy and may supply the stored electrical energy to the blood glucose measurement module 110 and / or the communication unit 140 .

The controller 150 may be implemented in hardware as application specific integrated circuits (ASICs), digital signal processors (DSPs), digital signal processing devices (DSPDs), programmable logic devices (PLDs), field programmable gate arrays (FPGAs) , Controllers, microcontrollers, microprocessors, and electrical units for performing functions.

In the memory unit 152,

The memory unit 152 may store a program for the operation of the controller 150, and may store the blood glucose measurement result in a database. For example, the memory unit 152 may be a flash memory type, a hard disk type, a multimedia card micro type, a card type memory (for example, SD or XD A static random access memory (SRAM), a read only memory (ROM), an electrically erasable programmable read-only memory (EEPROM), a programmable read-only memory (PROM) And an optical disc.

2, each configuration of the blood glucose meter 100 according to an embodiment of the present invention has been described generally. Hereinafter, the bio-battery module 120 will be described in detail with reference to FIGS. 3 and 4. FIG.

FIG. 3 is a view for explaining conversion of ATP and ADP, and FIG. 4 is a view for explaining a bioenergy module according to an embodiment of the present invention.

Detailed description of the bio-battery module (120)

The bio-battery module 120 can utilize ATP (adenosine triphosphate) in the body as an energy source. Referring to FIG. 3 for a detailed description of ATP, ATP can be defined as a compound in which three phosphates are bound to an adenine and a ribose structurally. At this time, phosphoric acid and phosphoric acid can be formed by high energy phosphoric acid bonding. When ATP is broken down into ADP (adenosine diphosphate) and inorganic phosphoric acid, high energy phosphoric acid bonds can break and release energy.

Hereinafter, the bio-battery module 120 will be described in more detail with reference to FIG.

4, the bio-battery module 120 may include at least one of a cathode 122, an anode 124, an enzyme 126, and an electrolyte 128. Hereinafter, each configuration will be described.

Electrons may be generated as the fuel in the anode 124 is oxidized. Electrons generated in the anode 124 may be provided to the cathode 122 along an external path. Also, the protons generated in the anode 124 may move to the cathode 122 through the electrolyte 128.

To this end, the enzyme 126 may be provided on the anode 124 to perform the function of generating protons and electrons from materials in the body. The enzyme 126 may comprise a hexokinase. The enzyme 126 may be composed of, for example, glucose 6-phosphate dehydrogenase (G6PDH). In addition, the enzyme 126 may further include at least one of vitamin K3 and benzyl viologen. Specific functions of the substance constituting the enzyme 126 will be described later.

The electrolyte 128 may provide a path for the protons generated from the anode 124 to be transferred to the cathode 122.

According to one embodiment, the cathode 122 and the anode 126 may also be provided in the Y-axis direction so that the blood flows in the Y-axis direction. Of course, the directions of the electrodes of the cathode 122 and the anode 126 may be different directions.

The anode 126 may be provided with an in vivo substance for generating electrical energy in blood. For example, the anode 126 may be provided with glucose and ATP. At this time, the hexokinase of the enzyme 126 provided in the anode 126 can convert the glucose and ATP into G6P (glucosuric 6-phosphate) and ADP. Then, glucose 6-phosphate dehydrogenase (G6PDH) in the enzyme 126 can convert G6P (clorose 6-phosphate) to NADH and a hydrogen proton. Then, vitamin K3 or benzyl viologen in the enzyme 126 can convert NADH to NADH + and e-. Thus, in the anode 126, proton and electrons can be generated from the substance in the body by the enzyme 126.

In this way, the bio-battery module 126 can produce and store electrical energy from materials in the body. The bio-battery module 126 may further include a blocking membrane (not shown) to control the amount of substance in the body provided to the anode 124.

The operation method of the bio-battery module, that is, the enzyme for the substance in the body or the substance in the body to be utilized, is not limited thereto and may be applied differently.

3 and 4, a bio-battery module 120 according to an embodiment of the present invention has been described. Hereinafter, a method of driving the blood glucose meter 100 according to one embodiment of the present invention will be described with reference to FIGS. 5 and 6. FIG.

5 is a view for explaining an example of driving an ATP-based blood glucose meter according to an embodiment of the present invention. According to the driving example described with reference to FIG. 5, the consumption of ATP can be variably controlled according to the blood glucose level.

Referring to FIG. 5, an example of driving the ATP-based blood glucose meter according to an embodiment of the present invention includes an electrical energy production step S110 through a bio-battery module, a step S120 of determining whether an electrical energy production amount exceeds a predetermined standard And continuing production of electrical energy through the bio-battery module (S130). Each step will be described in detail below.

In step S110, electrical energy production through the bio-battery module can be performed. For example, the controller 150 may command the production of electrical energy through the bio-battery module 120. The command of the controller 150 may be an algorithm of the controller 150 or an instruction obtained through the external electric machine 300. [ Accordingly, the bio-battery module 120 can produce electrical energy based on ATP, as described above with reference to FIGS. 3 and 4. FIG.

In step S120, it can be determined whether the electric energy production amount exceeds a predetermined standard. This is to take advantage of the fact that electric energy production is closely related to blood glucose level since electric energy is produced based on glucose and ATP.

To this end, the controller 150 may store the electrical energy produced from the bio-battery module 120 in the memory unit 152 as current and / or voltage per unit time. The controller 150 may determine whether the magnitude of the current and / or voltage produced per unit time exceeds a predetermined criterion. The predetermined criterion may be a reference value set by a medical professional, a diet expert, or the like. For example, a predetermined criterion may correspond to an allowed blood sugar amount based on an event such as time or before / after a meal. More specifically, when the allowed amount of blood glucose before meal is A1, the predetermined criterion may be A1? Corresponding to A1. If the allowed amount of blood glucose after meal in the same manner is A2, the predetermined criterion may be A2? Corresponding to A2.

Accordingly, the controller 150 can determine whether the electric energy produced through the bio-battery module 120 exceeds a predetermined standard. If the electrical energy current and / or voltage produced per unit time exceeds a predetermined criterion, it may mean that the blood glucose level is higher than the normal range. More specifically, when the electric energy current and / or voltage produced per unit time exceeds A1 ?, the blood glucose level may be higher than the normal range. In addition, when the electric energy current and / or voltage produced per unit time exceeds A2 ?, the blood glucose level may be higher than the normal range.

The electric energy production through the bio-battery module can be continued in step S130. As a result of the determination in step S120, the controller 150 may continue to produce electric energy through the bio-battery module 130 when the amount of electric energy produced exceeds a predetermined standard. Through this, the risk of hypertension can be alleviated by reducing the amount of blood clocose and ATP. In addition, it can be used for diet such as weight control by forcibly consuming blood sugar. In this case, when the blood glucose is simply consumed, the risk of hypoglycemia may occur. However, when the blood glucose is consumed based on the blood glucose level, it is remarkable that the health can be improved while eliminating the sudden health risk. In addition, by forcing the forced blood glucose consumption to maintain the blood glucose level in the body within the health range, diabetic patients can be relieved from the difficulty of repeated insulin administration.

If the electric energy production amount is equal to or less than the predetermined standard in step S120, the apparatus can enter the standby state.

Therefore, according to the driving example described with reference to FIG. 5, it is possible to forcibly consume blood glucose while preventing a risk of abnormally decreasing blood glucose.

Hereinafter, an example of driving the ATP-based blood glucose meter according to an embodiment of the present invention has been described with reference to FIG. Hereinafter, another driving example will be described with reference to Fig.

6 is a view for explaining another driving example of an ATP-based blood glucose meter according to an embodiment of the present invention. According to the driving example described with reference to FIG. 6, it is possible to provide a variable blood glucose measurement method considering the remaining amount of the bio-battery module. For the driving example to be described with reference to FIG. 6, it is assumed that the blood glucose measurement module 110 is a module that measures blood glucose based on impedance difference.

Referring to FIG. 6, an example of driving the ATP-based blood glucose meter according to another embodiment of the present invention includes a step S210 of determining whether the stored energy of the bio-battery module is below a reference value (S210) (S220), and measuring the blood glucose level in a manner different from the step S220 (S230). Each step will be described in detail below.

In step S210, it can be determined whether or not the stored energy of the bio-battery module is less than or equal to a reference value. That is, the controller 150 can determine whether the electric energy stored in the bio-battery module 120 is less than a reference value. In other words, the controller 150 can determine whether the remaining amount of the electric energy stored in the bio-battery module 120 is sufficient. According to the determination result, step S220 may be performed if the remaining amount of the stored electric energy is equal to or less than the predetermined reference value, and if the predetermined amount is equal to or greater than the predetermined reference value, the blood glucose amount may be measured in a manner different from step S220.

In step S220, the blood glucose level can be estimated through the electric energy production amount of the bio-battery module. Step S220 may be implemented in a situation where the bio-battery module 120 may be discharged. In this case, there is a need for a solution for continuously measuring the blood glucose while preventing the blood glucose meter 100 from being completely discharged and stopping its operation. Accordingly, when the remaining amount of the bio-battery module 120 is equal to or less than a predetermined reference value, the controller 150 can estimate the blood sugar amount based on the amount of electric energy produced per unit time. Thereby, discharge can be prevented and blood glucose measurement can be continuously performed.

In step S230, the blood sugar amount can be measured in a manner different from that in step S220. Step S230 can be implemented in a situation in which the remaining charge amount of the bio-battery module 120 is sufficient and more accurate blood glucose measurement is required. The control unit 150 may supply the electric energy stored in the bio-battery module 120 to the blood glucose measurement module 110 to measure blood glucose through the blood glucose measurement module 110.

Therefore, according to the driving example described with reference to FIG. 6, the blood glucose measurement method can be variably controlled in consideration of the remaining battery level.

1 to 6, a blood glucose meter and its driving examples according to an embodiment of the present invention have been described. According to the blood glucose meter of the embodiment of the present invention, since it can be self-charged based on the substance in the body in the state of being invaded in the body, various advantages can be provided. Particularly, patients who are taking anti-thrombotic / coagulant drugs at all times, those with hemophilia, and those with weak immunity are more difficult to perform blood glucose monitoring. However, since the blood glucose meter according to an embodiment of the present invention does not require additional operation for charging the battery after the first insertion operation, the convenience of blood glucose measurement can be greatly increased. Also, since the blood glucose meter according to an embodiment of the present invention can self-charge, the size of the battery can be reduced. Therefore, it is applicable to newborn babies and infants.

Further, the blood glucose meter according to an embodiment of the present invention may have a self-learning function. For example, the blood glucose value measured by the blood glucose meter and the blood glucose value measured by the invasive method according to an embodiment of the present invention may be stored in the memory unit and prepared for it, so that the blood sugar value measured by the glucose meter can be appropriately corrected.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the scope of the present invention is not limited to the disclosed exemplary embodiments. It will also be appreciated that many modifications and variations will be apparent to those skilled in the art without departing from the scope of the present invention.

110: blood glucose measurement module
120: a bio-battery module
140:
150:
152:

Claims (7)

A blood glucose measurement module inserted into the body to measure blood glucose; And
And a bio-battery module inserted in the body to produce electric energy based on the substance in the body and supply the produced electric energy to the blood glucose measurement module,
Further comprising a controller for controlling at least one of the blood glucose measurement module and the bio-battery module,
The blood glucose measurement module measures the amount of blood glucose in the body based on the electrical energy produced by the bio-battery module,
Wherein the control unit forcibly drives the bio-battery module to forcibly consume blood glucose in the body when the amount of electric energy produced through the bio-battery module exceeds a predetermined standard. The method according to claim 1,
Wherein the bio-
An anode formed with an enzyme, an electrolyte, and a cathode electrode,
When the substance in the body is glucose and ATP, the enzyme is an ATP-based blood glucose meter that is glucose-6-phosphoethedehydegenase. 3. The method of claim 2,
Wherein the anode electrode generates NADH through the enzyme and oxidizes the NADH to produce the electrical energy. delete The method according to claim 1,
The blood glucose measurement module measures an amount of blood glucose based on a difference in impedance. delete The method according to claim 1,
The ATP-based blood glucose meter changes the blood glucose measurement method based on the amount of electric energy stored in the bio-battery module.
KR1020160169228A 2016-12-13 2016-12-13 Blood Sugar Detector Charging based on ATP KR101902078B1 (en)

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PCT/KR2016/015345 WO2018110756A1 (en) 2016-12-13 2016-12-27 Adenosine triphosphate-based blood glucose monitoring device

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Citations (2)

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JP2007232378A (en) 2006-02-27 2007-09-13 Sumitomo Electric Ind Ltd Biosensor system and its measuring instrument
JP2009536441A (en) 2006-05-05 2009-10-08 スペンサー ジェイ ジー エップス Embedded voltaic battery

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KR101981370B1 (en) * 2013-06-05 2019-05-22 톈진 인스티튜트 오브 인더스트리얼 바이오테크놀로지, 차이니즈 아카데미 오브 사이언시스 Complete oxidation of sugars to electricity by using cell-free synthetic enzymatic pathways
US20150196224A1 (en) * 2014-01-16 2015-07-16 Dermal Therapy (Barbados) Inc. Implantable Sensor and Method for Such Sensor
KR20160013596A (en) * 2014-07-28 2016-02-05 김성우 On-demand Measurement of Blood Glucose

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007232378A (en) 2006-02-27 2007-09-13 Sumitomo Electric Ind Ltd Biosensor system and its measuring instrument
JP2009536441A (en) 2006-05-05 2009-10-08 スペンサー ジェイ ジー エップス Embedded voltaic battery

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