KR101889357B1 - Ion-suppiy apparatus for nano drug delivery of ocular - Google Patents

Abstract

The present invention relates to an ion supply device for delivering nanodrug in eyes, comprising: a drug supply part supplying a therapeutic drug to the eye; an electrode part for flowing a current; and a base wearing part hung on the ear of a patient while the electrode part is placed, and put on the face of a patient as a leg part for supporting a position of the base attachment part is provided at one side. According to the present invention, the ion supply device is simply worn on the eye of the patient by having a form of glasses, thereby increasing convenience in treatment while suppressing pain or unpleasant feeling due to detachment and attachment of an electrode during the treatment. In addition, it is possible to increase satisfaction of the patient during the treatment and therapeutic effects on the eye since the electrode can be precisely positioned around the eye of the patient.

Description

FIELD OF THE INVENTION [0001] The present invention relates to an ion supply device for an eye,

BACKGROUND OF THE INVENTION 1. Field of the Invention [0001] The present invention relates to an ion supply device for nano drug delivery in eyes, and more particularly, to an eye supply device for delivering nano drug in an eye.

In general, drugs are administered to the eyes for the purpose of treating the eyes, and drugs are used to be injected between the eyelids and the eyeballs.

In addition, an eye ion supply device is used to effectively penetrate the drug into the eyeball for the purpose of injecting the drug for the purpose of treating the eye, and in order to treat the eye disease such as cataract surgery, An eye ion supply device is used.

The eye's ion supply uses an electromotive force to transfer ionic chemicals through the cornea to be absorbed by nearby tissue or blood.

Korean Patent Laid-Open No. 10-2008-0080573 entitled " Ocular Ion Osmosis Therapy Device " (published on Sep. 4, 2008) has been proposed as a prior patent of the ion supply device of the eye.

Conventionally, an ion supply device for an eye includes an electrode body which is attached to the periphery of an eye to flow a current, and a current is supplied to the periphery of the eye through the electrode body in a state where a drug is supplied to the eye, .

Conventionally, an ion-supplying device for an eye has an electrode fixing fixture using a double-sided tape attached to both sides of a head of a patient, and both ends of the electrode body are respectively fixed to an electrode fixation fixture, thereby positioning the electrode body around the eye .

However, in the conventional eye ion supply device, it is necessary to attach an electrode fixation fixture using double-sided tape to both sides of the head of the patient before treatment, and it is troublesome to remove the fixation fixture after treatment, There was a problem that it caused discomfort and pain in the process of attaching and detaching.

 If the fixture for fixing the electrode can not be attached to the correct position, it is difficult to attach the electrode fixture to the correct treatment site. Therefore, the fixture for fixing the electrode fixture frequently needs to be repeated in order to position the electrode body to the correct position.

Korean Patent Laid-Open No. 10-2008-0080573 " Anionic iontophoretic device " (disclosed on September 4, 2008)

It is an object of the present invention to provide an ion supply device for nano drug delivery in eyes that can be easily worn on a patient's eye, thereby enhancing convenience in treatment.

It is another object of the present invention to provide an ion supply device for nano drug delivery in the eye, which can accurately position the electrodes around the eye of the patient, thereby improving the therapeutic effect of the eye.

According to an aspect of the present invention, there is provided a medical device comprising: a drug supply unit for supplying a therapeutic drug to the eye; an electrode unit for flowing current; and at least one of the upper eyelid and the lower eyelid, The present invention provides an ion supply device for nano drug delivery for eyes including a base wear part which is shielded.

In the present invention, the drug supply unit may include a drug discharge nozzle unit provided in the base wearer unit and supplying snow to the eye between the lower eyelid and the upper eyelid in a state in which the user drains the drug, and a drug storage unit A drug supply line unit for connecting the drug storage unit and the drug discharge nozzle unit, and a pump unit for supplying the drug in the drug storage unit to the drug discharge nozzle unit through the drug supply line unit.

In the present invention, the base attaching portion is provided with an electrode attaching portion to which the electrode attaching portion can be attached, and the electrode attaching portion can be moved forward and backward.

In the present invention, the electrode mounting portion may be provided on the base wearing portion so as to be movable up and down.

In the present invention, the electrode attaching portion may be provided in the base wearing portion so as to be movable leftward and rightward in the lateral direction.

The present invention can provide an ion supply device for nano drug delivery in eyes, further comprising a control body part connected to the electrode part through a power supply line part and supplying power to the electrode part.

In the present invention, the base wear part is provided with a first connection terminal part to which the power supply line part is connected, the power supply line part is connected to the control part of the control body part, and the first connection terminal part is detachably connected to the first connection terminal part And a second connection terminal unit connected to the second connection terminal unit.

In the present invention, the electrode unit is provided with a pressure sensor capable of sensing pressure when it contacts the skin, and the pressure sensor is electrically connected to the control body unit to transmit sensed pressure to the control body unit, The main body can notify when the pressure value detected by the pressure detection sensor reaches a predetermined pressure value.

The electrode unit may include an anode member and a cathode member. The base attaching unit may include a first electrode mount unit and a second electrode mount unit that can be mounted with the anode member and the cathode member spaced apart from each other.

In the present invention, the first electrode mounting portion is provided on the upper side of the base wearing portion, and the second electrode mounting portion is provided on the lower side of the base wearing portion, and the anode member is contacted to the upper side of the eye with respect to the patient's eye , The cathode member can be brought into contact with the underside of the eye.

In the present invention, the base wearing portion may include the first electrode moving portion for moving the first electrode mounting portion forward and backward, and the second electrode moving portion for moving the second electrode mounting portion forward and backward.

In the present invention, an electrode lateral moving body may be provided on an upper portion of the base wearing portion, the electrode lateral moving body including the first electrode mounting portion and the first electrode moving portion movably to the left and right.

The electrode transverse moving body may include a first transverse moving member that is coupled to an upper portion of the base wearing portion so as to be horizontally movable, and a second transverse moving member that is coupled to the upper portion of the first transverse moving member so as to be movable up and down, And a second transverse moving member having the first electrode moving unit.

In the present invention, the electrode lifting mobile body provided with the second electrode mounting portion and the second electrode moving portion and movable upward and downward is provided at a lower portion of the base wearable portion, and the electrode lifting mobile body is movable up and down And a rising / falling slit part which is coupled to the lower part of the body.

In the present invention, the base wearing portion is provided with a first nozzle moving slit portion longitudinally coupled to the drug discharging nozzle portion so as to be movable upward and downward, and the first nozzle moving slit portion is provided on both sides of the first nozzle moving slit portion, And a plurality of second nozzle moving slit portions formed in the lateral direction and communicating with the first nozzle moving portion, the second nozzle moving slit portion being formed at a height difference and guiding the lateral movement of the drug discharging nozzle portion.

In the present invention, the power supply line unit may include a first power supply line having one end connected to the electrode unit and the other end connected to the first connection terminal unit, and a first power supply line connected to the first connection terminal unit, And a second power supply line having the other end connected to the control unit of the control unit.

In the present invention, the base wear part includes a leg part hanging on the ear of the patient, the leg part includes a first leg body connected to both sides of the base wear part, and a second leg body movably coupled to the first leg body, May include a second leg body that is caught in the ear.

In the present invention, the base wearing part may include a leg part hanging on the ear of the patient, and the first electrode mounting part may be provided on the leg part so that the anode member may contact the skin on the upper side of the ear.

In the present invention, the base wearer may be provided with an infrared LED capable of heating the skin by irradiating light and a shield plate for preventing light emitted from the infrared LED from entering the eye of the patient.

In the present invention, the base wearer may be of the goggle type having an elastic band member worn on the head of the patient and worn in close contact with the patient's face.

In the present invention, the base wear part is provided with a frame part which is in close contact with the face of the patient and in which the mounting part is formed, into which the electrode part can be embedded, an infrared LED is positioned inside the mounting groove, The gel layer to be contacted can be laminated.

The present invention is an eyeglass type that is easily worn on the eyes of a patient to increase convenience in treatment and prevents discomfort or pain caused by detaching and attaching electrodes during treatment, thereby improving patient's satisfaction during treatment.

The present invention is capable of accurately positioning the electrodes around the eye of a patient, thereby improving the therapeutic effect of the eye.

1 is a perspective view showing an embodiment of an ion supplying device for nano drug delivery in the eye according to the present invention.
2 is a cross-sectional view showing one embodiment of an ion supply device for nano drug delivery in the eye according to the present invention.
FIG. 3 is a perspective view showing another embodiment of an ion supply device for nano drug delivery in the eye according to the present invention. FIG.
4 is a perspective view showing still another embodiment of an ion supply device for nano drug delivery in the eye according to the present invention.
FIG. 5 is a perspective view showing an example in which an ion supply device for nano drug delivery in the eye is performed in a goggle type according to the present invention. FIG.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings so that those skilled in the art can easily carry out the present invention. The present invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Like parts are designated with like reference numerals throughout the specification.

FIG. 1 is a perspective view showing one embodiment of an ion supply device for nano drug delivery in the eye according to the present invention, FIG. 2 is a sectional view showing an embodiment of an ion supply device for nano drug delivery in the eye according to the present invention to be.

1 and 2, an embodiment of an ion supply device for nano drug delivery in the eye according to the present invention will be described in detail below.

The ion supply device for transferring nano-drug to the eye according to the present invention includes a drug supply part 100 and an electrode part 200 for making current flow in contact with the patient's skin.

The electrode unit 200 includes an anode member 210 and a cathode member 220 by applying current to the patient's skin in contact with the skin of the patient, that is, around the eyes.

The positive electrode member 210 and the negative electrode member 220 are separated from each other and contact the skin of the patient so that current flows around the eye of the patient so that the drug can be penetrated into the tissue through noninvasive iontophoresis.

The drug supply part 100 may be formed of a nanoparticle formulation that supplies a drug containing nanoparticles for delivering a drug into tissues between the eyeball and the eyelid of the patient and is located inside the upper eyelid or inside the upper eyelid, Type drug may be stored in a separate container and then formed into a droplet so as to be dropped into the patient's eye to supply the drug to the patient's eye.

The drug supply unit 100 may be integrally provided in the electrode unit 200 and may inject drugs into the eye through the patient's skin when the electrode unit 200 contacts the patient's skin.

At this time, the electrode unit 200 may contact the lower eyelid or the upper eyelid so that the drug can be infiltrated into the eyeball through the lower eyelid or the upper eyelid and infiltrated into the eyeball tissue.

The drug includes nanostructured drug delivery particles containing a mucoadhesive polymer.

In the present invention, the drug supply unit 100 is provided in the base wear unit 300, which is supported by the legs 310 of the patient's ear and worn on the patient's face.

The base wearer 300 is placed on the face of the patient so as to cover at least one of the upper eyelid and the lower eyelid.

The drug supply part 100 includes a drug discharge nozzle part 110 provided in the base wear part 300 for supplying the eye to the eye between the lower eyelid and the upper eyelid in a state in which the eye is opened by discharging the drug, A drug supply line unit 120 connecting the drug storage unit and the drug discharge nozzle unit 110 to the drug discharge line unit 120, And a pump unit (not shown) for supplying the pump unit 110 with a pump.

The drug discharge nozzle unit 110 is formed by forming a droplet of drug into a droplet and dropping it between the lower eyelid and the upper eyelid to supply the drug to the eye. If the patient closes his or her eyes after the drug drops on the eyeball, the drug is delivered between the eyeball and the lower eyelid or between the eyeball and the upper eyelid.

The ion supply device for nano-drug delivery in the eye according to the present invention is connected to the electrode unit 200 through the power supply line unit 410 to supply power to the electrode unit 200, And a control body 400 capable of adjusting the intensity of a current applied to the skin.

The control unit 400 includes a power supply line unit 410 connected to the electrode unit 200 to apply electrical power to the electrode unit 200.

The control unit 400 includes a power supply cable 420 having a plug 421 to be plugged into an outlet so that the plug 421 can be operated by being plugged into a power supply set and supplied with power.

The control body unit 400 is connected to the drug supply line unit 120. The control body unit 400 is connected to the drug discharge nozzle unit 110 through a drug storage unit (not shown) and a drug supply line unit 120 A pump unit (not shown) may be provided.

The control unit 400 includes a control unit (not shown) for controlling the operation of the electrode unit 200 and the operation of the pump unit and includes a switch unit 430 for controlling the operation of the electrode unit 200 and the operation of the pump unit And a display unit 440 for displaying the operation of the electrode unit 200 and the operation state of the pump unit on a screen.

The switch unit 430 is electrically connected to the control unit so that the operator can control the operation of the electrode unit 200 and the operation of the pump unit through a touch.

The control unit 400 can periodically change the intensity of the current and can confirm the change in the intensity and current of the current applied from the electrode unit 200 through the display unit 440. [

In addition, the control body unit 400 can display the supply amount of the drug supplied to the eye of the patient through the drug discharge nozzle unit 110 through the display unit 440 or the number of times of supply of the drug.

Meanwhile, the base wearer 300 may be formed in a shape capable of covering the two eyes of the patient, and may include the nose holder 340.

More specifically, the base wear part 300 includes a first blind part 320, a second blind part 330, a first blind part 320 and a second blind part 330, And a nose receiver 340 positioned on the nose of the patient.

The leg portions 310 are respectively provided on both sides of the base wearing portion 300 and bent portions are formed so that a portion of the leg portions 310 can be hooked on the ear.

The base wearer 300 is configured such that the nose holder 340 is seated in the nose of the patient and the leg 310 is caught on the patient's ear so that the first blind 320 and the second blind 330 are positioned in the patient's It is worn on the patient's face to cover both eyes.

The electrode unit 200 is provided on the base wear unit 300 to allow the electrode unit 200 to contact the lower eyelid or the upper eyelid of the patient when worn on the patient's face.

The base wearer 300 is equipped with an infrared LED 301 capable of heating the skin by irradiating light and a shield plate 302 for preventing light emitted from the infrared LED 301 from flowing into a patient's eye .

The infrared LED 301 is located on the lower side of the base wearer 300 and irradiates infrared rays to the lower eyelid or the side close to the lower eyelid so as to heat the eye so that the ion supply through the drug can be smoothly performed .

The shielding plate 302 is located on the upper side of the infrared LED 301 and can prevent the light emitted from the infrared LED 301 from flowing into the eyes of the patient.

The base attaching part 300 may be provided with an electrode mounting part 500 on which at least one of the anode member 210 and the cathode member 220 can be mounted.

The electrode mounting part 500 is moved forward and backward so that the mounted electrode part 200 can be brought into close contact with the skin of the patient.

The electrode mounting part 500 is provided on the base wearing part 300 so as to be movable up and down so that the electrode part 200 is moved to a proper position for contact with the skin according to the position of the patient's eyes or the size of the eyes .

The electrode mounting part 500 is provided to the base wearing part 300 so as to be movable in the lateral direction to the left and right so that the electrode part 200 moves to an appropriate position for contacting the skin according to the position of the eyes or the size of the eyes. .

The electrode mounting portion 500 can be positioned below the base wearing portion 300 and contact the lower eyelid of the patient.

The electrode unit 200 may be detachably coupled to the electrode mounting unit 500 to change the positions of the positive electrode and the negative electrode according to the need for treatment, or may be replaced with an appropriate size depending on the patient.

The electrode unit 200 may be detachably coupled to the electrode mounting unit 500 with a bolt fastening structure or may be detachably coupled to the electrode mounting unit 500 with a tight fitting structure.

The base attachment part 300 may include a first connection terminal part 350 to which the power supply line part 410 is connected. The power supply line unit 410 is connected to the control unit of the control unit 400 and has a second connection terminal unit 411 connected to the first connection terminal unit 350 at one end thereof in a detachable manner.

One of the first connection terminal portion 350 and the second connection terminal portion 411 is formed as a protruded terminal and the other of the first connection terminal portion 350 and the second connection terminal portion 411 is inserted As shown in Fig.

The power supply connection line connecting the electrode mounting part 500 and the first connection terminal part is provided in the base wearing part 300 so that the electric power can be supplied to the electrode part 200 mounted on the electrode mounting part 500.

The electrode mounting portion 500 is provided with a first connection terminal 500a connected to a power connection line and the electrode portion 200 is provided with a second connection terminal 200a connected to the first connection terminal and electrically connected thereto The first connection terminal 500a is connected to the second connection terminal 200a when the electrode unit 200 is mounted on the electrode mounting unit 500 so that the control of the control unit 400 and the electrode unit 200 can be connected .

One of the first connection terminal 500a and the second connection terminal 200a is formed as a protruded terminal and the other of the first connection terminal 500a and the second connection terminal 200a is inserted As shown in Fig.

The first connection terminal 500a formed by the protruding terminal is inserted into the second connection terminal 200a formed by the insertion terminal so that the electrode unit 200 is coupled to the electrode mounting unit 500 and is connected to the control main body (Not shown).

The base wear part 300 is provided with a supply line connecting part 360 for connecting the drug supply line part 120 and a drug supply path for connecting the supply line connecting part 360 and the drug discharge nozzle part 110, Can be supplied to the drug discharge nozzle unit (110).

A line coupler 121 detachably connected to a supply line coupler 360 provided in the base wearer 300 is provided at an end of the drug supply line unit 120, The drug supply channel and the drug supply line unit 120 can be connected by being detachably coupled to the connection unit 360.

It is noted that the drug supply line unit 120 may be directly connected to the drug discharge nozzle unit 110 to supply the liquid drug stored in the drug storage unit to the drug discharge nozzle unit 110.

That is, the drug discharging nozzle unit 110 may be provided with a line connecting groove 121 in which the line connecting hole 121 of the drug supplying line unit 120 is detachably coupled, and the line connecting hole 121 may be formed in the line connecting groove 121 The drug supply line unit 120 is connected to the drug discharge nozzle unit 110 so that the drug can be supplied to the drug discharge nozzle unit 110.

The drug supply line unit 120 is detachably coupled to the line connection groove portion provided in the supply line connection portion 360 or the drug discharge nozzle portion 110 provided in the base wearing portion 300, And may be connected to other base wear parts 300 depending on the face size or treatment method.

The base attaching part 300 may include a first electrode attaching part 510 and a second electrode attaching part 520 to which the anode member 210 and the cathode member 220 may be separately mounted.

The first electrode mounting part 510 is provided on the upper side of the base wearing part 300 and the second electrode mounting part 520 is provided on the lower side of the base wearing part 300, And the cathode member 220 is brought into contact with the underside of the eye so that the drug nanoparticles can be effectively penetrated into the tissue of the eyeball.

In more detail, the first electrode mounting portion 510 is positioned to contact the patient's skin at the upper side of the electrode brow and the second electrode mounting portion 520 is positioned to contact the lower eyelid.

The first electrode mounting part 510 and the second electrode mounting part 520 are provided in the first blind part 320 and the second blind part 330 so that drugs can be simultaneously injected into both eyes, The drug may be selectively injected into any one of the eyes.

The anode member 210 and the cathode member 220 may be detachably coupled to the first electrode mounting portion 510 and the second electrode mounting portion 520.

The first electrode mounting portion 510 and the second electrode mounting portion 520 are each provided with a first connection terminal 500a connected to a power supply connection line and the anode terminal 210 and the cathode terminal 220 are provided with a first connection terminal 500a, The first connection terminal 500a is connected to the second connection terminal 200a when the electrode unit 200 is mounted on the electrode mounting unit 500. The first connection terminal 500a is electrically connected to the second connection terminal 200a, So that the electrode unit 200 and the control of the control body unit 400 can be connected to each other.

The second connection terminal 200a may be formed as a protruding terminal, and the first connection terminal 500a may be formed as an insertion terminal having a terminal groove formed therein.

The first electrode moving part 600 moves the first electrode mounting part 510 toward the base mounting part 300. The first electrode moving part 600 moves the first electrode mounting part 510 forward and backward, , So that the anode member 210 can be brought into contact with the skin of the patient.

The second electrode moving part 700 includes the second electrode mounting part 520 and the second electrode moving part 700 for moving the second electrode mounting part 520 forward and backward. So that the cathode member 220 can be brought into contact with the skin of the patient.

The first electrode moving part 600 may include a first back and forth moving screw member 610 having one end rotatably coupled to the first electrode mounting part 510 and threaded through the base wearing part 300 have.

A first grip portion 620 is provided at the other end of the first back and forth moving screw member 610 to allow the first grip portion 620 to rotate and to easily rotate the first and second moving screw members 610.

The first electrode mounting portion 510 is moved forward and backward according to the rotation direction of the first front-rear movable screw member 610 when rotating, so that the anode member 210 can be brought into contact with the skin of the patient.

The second electrode moving part 700 includes a second front and rear moving screw member 710 having one end rotatably coupled to the second electrode mounting part 520 and threaded through the base wearing part 300 can do.

A second handle 720 is provided at the other end of the second back and forth moving screw member 710 to hold the second handle 720 so that the second back and forth moving screw member 710 can be easily rotated.

The second electrode mounting portion 520 is moved forward and backward in accordance with the rotation direction of the second front-rear movable screw member 710, so that the anode member 210 can be brought into contact with the skin of the patient.

Although not shown, the first electrode moving part 600 and the second electrode moving part 700 may have a structure of a set screw that passes through the base wearing part 300 to fix the position of the moving bar and the moving bar, And a structure for converting the rotational force of the motor and the motor into a linear motion.

It is noted that the first electrode moving part 600 and the second electrode moving part 700 can be variously modified by a known linear moving structure.

Each of the electrode units 200, that is, the positive electrode member 210 and the negative electrode member 220, is provided with a pressure sensor (not shown) 400 to transmit the sensed pressure to the control body unit 400. [

The control body unit 400 notifies the electrode unit 200, that is, the anode member 210 and the cathode member 220, to the skin and an appropriate pressure (pressure) when the pressure value sensed by the pressure sensor reaches a preset pressure value, That is, the anode member 210 and the cathode member 220 are prevented from excessively pressing the skin to cause pain, and the electrode unit 200, that is, the anode member 210, And the cathode member 220 are prevented from being properly applied to the patient's skin due to unstable contact with the skin, and the current can be stably applied to the skin of the patient.

The electrode transverse body 800 having the first electrode mounting portion 510 and the first electrode moving portion 600 and being movable left and right may be provided on the base wearing portion 300.

In more detail, the electrode transverse body 800 is movably coupled to the upper portions of the first blind 320 and the second blind 330, The first electrode mounting portion 510 is provided and the first back and forth moving screw member 610 is penetrated and screwed to the electrode lateral moving body 800.

The electrode transverse body 800 includes a first transverse moving member 810 coupled to an upper portion of the base wearing portion 300 so as to be transversely movable, a second transverse moving member 810 coupled to the upper portion of the first transverse moving member 810, And a second transverse member 820 coupled to the first electrode mounting portion 510 and the first electrode moving portion 600.

The electrode transverse moving body 800 further includes a position fixture 830 for fixing the height of the second transverse moving member 820 and releasing the fixed state to allow the second transverse moving member 820 to move up and down .

The position fixture 830 is a set screw that is screwed through the first transverse member 810 and presses the second transverse member 820 to fix the position of the second transverse member 820 And it is also possible to carry out modification by various known locking structures.

The first electrode mounting portion 510 is moved together with the transverse movement of the electrode lateral movement body 800 and moved up and down together with the second transverse movement member 820 to adjust the contact position of the anode member 210 have.

The second electrode mounting portion 520 and the second electrode moving portion 700 are provided on the lower portion of the base wearing portion 300 and the electrode lifting moving body 521 movable up and down can be provided.

In more detail, the first blind part 320 and the second blind part 330 are provided with elevating and lowering slit parts 370, respectively, which are coupled with the electrode elevating moving body 521 so as to be movable upward and downward. The second electrode mounting portion 520 is provided on the surface of the electrode lifting body 521 facing the patient's face and the second longitudinal moving screw member 710 is threadedly coupled to the electrode lifting body 521 .

The second electrode mounting portion 520 is moved together with the upward and downward movement of the electrode elevating moving body 521 to adjust the contact position of the cathode member 220.

The cathode member 220 is positioned so as to accurately contact the lower eyelid of the patient by the upward and downward movement of the electrode lifting mobile body 521 in consideration of the size of the patient's eye or the position when the base wear part 300 is worn .

Meanwhile, the drug discharging nozzle unit 110 is movable upward and downward and is movably coupled to the base wearing unit 300 so as to be movable left and right so that the size of the patient, the position when the base wearing unit 300 is worn, So that the drug discharge nozzle unit 110 can be positioned at a position where the drug can be supplied to the eye of the patient.

The first blind part 320 and the second blind part 330 are provided with a first nozzle moving slit part (not shown) vertically movably coupled to the base wear part 300, that is, the first blind part 320 and the second blind part 330, 380 are formed on both sides of the first nozzle moving slit part 380 and communicated with the first nozzle moving slit part 380 in the lateral direction, A plurality of second nozzle moving slit portions 390 for guiding the lateral movement of the drug dispensing nozzle portion 110 are provided and the drug discharging nozzle portion 110 is moved to the first nozzle moving slit portion 380 and the second nozzle moving slit portion 390 Lt; / RTI >

The drug discharge nozzle unit 110 includes a first nozzle body 111 located inside the wearer and having a discharge hole for discharging a drug toward a patient's eye, a first nozzle body 111 located outside the wearer, And a second nozzle body 112 screwed to the second nozzle body 112.

The base wear part 300 is pressed between the first nozzle body 111 and the second nozzle body 112 by tightening the second nozzle body 112 by tightening the bolts and then tightening the first nozzle body 111 The first nozzle body 111 and the second nozzle body 112 are fixed by rotating the second nozzle body 112 in a reverse direction by rotating the first nozzle body 112 in the opposite direction, The second nozzle moving slit portion 390, and the second nozzle moving slit portion 390, respectively.

The drug discharge nozzle portion 110 is moved upward and downward through the first nozzle moving slit portion 380 and is moved to the left and right by the second nozzle moving slit portion communicated with the first nozzle moving slit portion 380 It can be accurately positioned at a position where the drug can be supplied to the patient's eye.

3 is a perspective view showing another embodiment of an ion supply device for nano drug delivery in the eye according to the present invention.

Referring to FIG. 3, the power supply line unit 410 connected to the control unit 400 may be directly connected to the electrode unit 200.

That is, one end of the power supply line unit 410 is connected to the anode member 210 and the cathode member 220, which are the electrode unit 200, and the first connection terminal unit 350 is provided at the other end side The first power supply line 410a and the second connection terminal portion 411 are detachably connected to the first connection terminal portion 350 at one end and the second connection terminal portion 411 is connected to the control portion of the control body portion 400 at the other end. And a second power supply line 410b.

One of the first connection terminal portion 350 and the second connection terminal portion 411 is formed as a protruded terminal and the other of the first connection terminal portion 350 and the second connection terminal portion 411 is inserted As shown in Fig.

4 is a perspective view showing still another embodiment of an ion supply device for nano drug delivery in the eye according to the present invention.

Referring to FIG. 4, the legs 310 of the base wearer 300 are adjustable in length and can be adjusted in length to fit the wearer's face size.

The leg portion 310 includes a first leg body 311 connected to both sides of the base wearing portion 300, a second leg body 311 movably coupled to the first leg body 311, (312).

The leg portion 310 fixes the position of the second leg body 312 and releases the fixed state so that the second leg body 312 can be moved forward and backward in the longitudinal direction .

The length fixture 313 is a set screw that is screwed through the first leg body 311 and presses the second leg body 312 to fix the position of the second leg body 312. In addition, It will be understood that the present invention can be implemented by various known locking structures.

In addition, the first electrode mounting portion 510 may be provided on the leg portion 310 so that the anode member 210 may contact the skin on the upper side of the ear.

The first electrode mounting portion 510 is moved forward and backward in the direction toward the head of the patient from the leg portion 310 so that the anode member 210 can be brought into close contact with the skin on the upper side of the ear.

That is, the leg portion 310 is provided with a first electrode moving portion 600 for moving the first electrode mounting portion 510 so that the anode member 210 can be accurately brought into contact with the skin on both sides of the patient's head.

The first electrode moving part 600 may include a transverse moving screw member 630 threaded through the second leg body 312 and having one end rotatably coupled to the first electrode mounting part 510 .

The first electrode mounting portion 510 can be moved forward and backward in accordance with the rotation direction of the transverse moving screw member 630 so that the anode member 210 can be brought into contact with or separated from the skin on both sides of the patient's head.

3 and 4, an embodiment of an ion supply device for nano drug delivery in the eye according to the present invention is an example in which the drug discharge nozzle part 110 is not provided in the base wear part 300, The drug storage part may include a drug storage part provided in the unit 200 to allow the drug storage part to contact the skin of the patient so that the therapeutic ingredient and ions in the drug can be supplied to the eye through the skin of the patient.

The electrode unit 200 may have a structure including an electrode for applying an electrode to the skin, a drug accommodating portion located around the electrode, and a drug accommodating portion, which is a structure disclosed in a known eye ion implanter, Is omitted.

In addition, the drug supply part 100 may be formed of a nanoparticle formulation which is placed inside the lower eyelid or inside the upper eyelid by supplying a drug containing nanoparticles for transferring the drug into the tissue between the patient ' s eye and eyelid Which is an embodiment of the present invention.

FIG. 5 is a perspective view showing an example in which an ion supply device for nano drug delivery for eyes according to the present invention is applied in a goggle type. Referring to FIG. 5, the base wear part 300 includes an elastic band member (300a), and may be formed in a goggle type to be worn on the face of a patient.

The base attachment portion 200 formed in a goggle type is provided with a frame portion which is in close contact with the face of the patient and a mounting groove in which the electrode portion 200 can be embedded is provided in the frame portion. An infrared LED 301 capable of heating the skin by irradiating light can be provided.

The infrared LED 301 is mounted on the substrate 301a and is supplied with electric power to the control body 400 and irradiates the infrared rays to the skin.

The mounting groove is located on the lower side of the rim and is positioned on the side close to the lower eyelid or lower eyelid so that a current is applied to the lower eyelid side to which the drug is supplied and the lower eyelid side is heated by the infrared LED 301, So that it can be performed more smoothly with the eyeball.

In addition, a gel layer 201 contacting the skin is provided on the surface of the electrode unit 200 so that current can be stably applied to the skin.

The present invention relates to a spectacle type which is easily worn on the eyes of a patient to increase convenience in treatment and prevents discomfort or pain caused by detachment of electrodes during treatment, thereby improving patient's satisfaction during treatment.

The present invention can accurately position electrodes around the eye of a patient, thereby improving the therapeutic effect of the eye.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed exemplary embodiments, Of the right.

100: drug supply unit 110: drug discharge nozzle unit
111: first nozzle body 112: second nozzle body
120: drug supply line section 121: line coupling port
200: electrode unit 200a: second connection terminal
210: anode member 220: cathode member
300: base wear part 310: leg part
311: first leg body 312: second leg body
313: Length fixture 320: First blind spot
330: second blind part 340: nose part
350: first connection terminal part 360: supply line connection part
370: ascending / descending slit portion 380: first nozzle moving slit portion
390: second nozzle moving slit part 400: control body part
410: power supply line part 410a: first power supply line
410b: second power supply line 411: second connection terminal portion
420: Power supply wire 421: Plug
430: switch unit 440: display unit
500: electrode mounting portion 500a: first connection terminal
510: first electrode mounting portion 520: second electrode mounting portion
521: Electrode lifting mobile body 600: First electrode moving part
610: first back and forth moving screw member 620: first handle portion
630: transverse moving screw member 700: second electrode moving part
710: second back and forth moving screw member 720: second handle portion
800: electrode lateral moving member 810: first lateral moving member
820: second transverse moving member 830:

Claims (21)

A drug supply part supplying the therapeutic drug to the eye;
An electrode portion for flowing a current; And
And a base wearing portion on which the electrode portion is placed and which is worn on the face of the patient to cover at least one of the upper eyelid and the lower eyelid,
Wherein the base attaching portion is provided with an electrode attaching portion to which the electrode attaching portion can be attached, and the electrode attaching portion can be moved forward and backward.
The method according to claim 1,
The drug supply unit includes:
A drug discharge nozzle unit provided at the base wearer and capable of supplying snow to the eye between the lower eyelid and the upper eyelid in a state in which the eye is opened by discharging the drug;
A drug storage part for storing a liquid drug;
A drug supply line unit connecting the drug storage unit and the drug discharge nozzle unit; And
And a pump unit for supplying the drug in the drug storage unit to the drug discharge nozzle unit through the drug supply line unit.
delete The method according to claim 1,
Wherein the electrode mounting portion is movable up and down to the base wearing portion.
The method according to claim 1 or 4,
Wherein the electrode attaching portion is movable leftward and rightward in the lateral direction to the base wearing portion.
The method according to claim 1,
And a control unit connected to the electrode unit through a power supply line unit to supply power to the electrode unit.
The method of claim 6,
Wherein the base wearer further comprises a first connection terminal portion to which the power supply line portion is connected,
Wherein the power supply line portion further comprises a second connection terminal portion connected to a control portion of the control body portion and detachably connected to the first connection terminal portion at one end side.
The method of claim 6,
The electrode unit may include a pressure sensor capable of sensing a pressure upon contact with the skin. The pressure sensor may be electrically connected to the control unit to transmit the sensed pressure to the control unit,
Wherein the control unit informs the eye when the pressure value detected by the pressure sensor reaches a preset pressure value.
The method according to claim 1,
Wherein the electrode portion includes an anode member and a cathode member,
Wherein the base attaching portion includes a first electrode attaching portion and a second electrode attaching portion that can be mounted so that the anode member and the cathode member are spaced apart from each other.
The method of claim 9,
Wherein the first electrode attaching portion is provided on the upper side of the base wearing portion and the second electrode attaching portion is included on the lower side of the base wearing portion so that the anode member contacts the upper side of the eye with respect to the patient's eye, Wherein the cathode member is brought into contact with the lower side of the cathode.
The method of claim 9,
Wherein the base attaching portion includes a first electrode moving portion moving the first electrode attaching portion forward and backward and a second electrode moving portion moving the second electrode attaching portion forward and backward, .
The method of claim 11,
And an electrode transverse moving body provided on the base wearing portion to move left and right with the first electrode mounting portion and the first electrode moving portion.
The method of claim 12,
Wherein the electrode lateral moving body comprises:
A first transversal member movably coupled to an upper portion of the base wearing portion; And
And a second transversal member movably coupled to an upper portion of the first transversal member and having the first electrode mounting portion and the first electrode moving portion.
The method of claim 9,
And an electrode elevating moving body including the second electrode mounting portion and the second electrode moving portion and movable up and down,
Wherein the base attaching portion includes an up-and-down slit portion to which the electrode lifting mobile body is movably coupled in an upward and downward direction.
The method of claim 2,
In the base wearing portion,
A first nozzle moving slit portion is provided in the longitudinal direction in which the drug discharge nozzle portion is movably coupled with the first nozzle,
A plurality of second nozzle moving slit portions formed on both sides of the first nozzle moving slit portion and communicating with the first nozzle moving slit portion in a lateral direction and having a height difference to guide lateral movement of the drug discharging nozzle portion, The ion supply device for nano drug delivery in the eye.
The method of claim 6,
The power supply line unit includes:
A first power supply line having one end connected to the electrode portion and the other end connected to the first connection terminal portion; And
And a second power supply line having a second connection terminal portion that is detachably connected to the first connection terminal portion at one end side and a control portion of the control body portion at the other end side, Supply device.
The method according to claim 1,
Wherein the base wearing part includes a leg part hanging on the ear of the patient,
Wherein,
A first leg body connected to both sides of the base wear part; And
And a second leg body movably coupled to the first leg body and having an end side hooked to the ear.
The method of claim 9,
Wherein the base wearing part includes a leg part hanging on the ear of the patient,
Wherein the first electrode mounting portion is provided in the leg portion and the anode member is in contact with the skin on the upper side of the ear.
The method according to claim 1,
Wherein the base attaching portion is provided with an infrared LED capable of heating the skin by irradiating light and a shielding plate for preventing light emitted from the infrared LED from entering the eyes of the patient, .
The method according to claim 1,
Wherein the base wearing part is a goggle type having an elastic band member to be worn on the head of a patient so as to be closely attached to a face of a patient.
The method of claim 20,
Wherein the base wearing portion is provided with a frame portion which is in close contact with the face of the patient and on which the mounting groove is formed,
Wherein an infrared LED is disposed inside the mounting groove, and a gel layer contacting the skin is laminated on a surface of the electrode unit.

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