KR101869894B1 - High-Frequency Handpiece for acne and treatment method thereof - Google Patents

High-Frequency Handpiece for acne and treatment method thereof Download PDF

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Publication number
KR101869894B1
KR101869894B1 KR1020170095388A KR20170095388A KR101869894B1 KR 101869894 B1 KR101869894 B1 KR 101869894B1 KR 1020170095388 A KR1020170095388 A KR 1020170095388A KR 20170095388 A KR20170095388 A KR 20170095388A KR 101869894 B1 KR101869894 B1 KR 101869894B1
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South Korea
Prior art keywords
high frequency
needle
acne
frequency
holder
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KR1020170095388A
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Korean (ko)
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윤성태
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주식회사 파나시
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Priority to KR1020170095388A priority Critical patent/KR101869894B1/en
Priority to PCT/KR2017/012968 priority patent/WO2019022308A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0502Skin piercing electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/06Electrodes for high-frequency therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/328Applying electric currents by contact electrodes alternating or intermittent currents for improving the appearance of the skin, e.g. facial toning or wrinkle treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36017External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Surgical Instruments (AREA)

Abstract

The present invention relates to a micro needle high-frequency system for acne disease treatment, and a method for operating the same. The micro needle high-frequency system for acne disease treatment comprises a main body, a high-frequency generating unit, and a high-frequency handpiece. The high-frequency generating unit is mounted in one side of the main body and includes a high-frequency control board and high-frequency power connected to the high-frequency control board. The high-frequency handpiece connects one end unit to the high-frequency generating unit and includes a handle and a needle cartridge. The handle forms an opening hole in the other end unit of the high-frequency handpiece. The needle cartridge is detachably coupled to one side of the handle and includes a micro needle inserted into skin to transmit high-frequency. The micro needle cartridge includes: a holder which opens both sides and forms a passage inside; a needle piece body which is combined with one side of the holder and forms the micro needle; and a connector which is combined with an opening unit of the other side of the holder, is connected to one side of the needle piece body, and forms an insertion unit in the other side. The present invention relates to the method for operating the micro needle high-frequency system for acne disease treatment capable of enabling an operator to touch the high-frequency handpiece to the skin to be operated by using the micro needle high-frequency system for acne disease treatment and to apply a high-frequency voltage to the high-frequency generating unit. Therefore, the present invention can treat acne and improve acne skin.

Description

TECHNICAL FIELD [0001] The present invention relates to a microneedle high frequency system for treating an acne disease,

The present invention relates to a microneedle high frequency system for treating acne diseases, and more particularly to a microneedle high frequency system for use in various types of acne such as adult acne, wheat acne, recurring acne, purulent acne and juvenile acne. And to a method of operation for treating acne disorders.

The skin that covers our entire body consists of three layers: the epidermal layer, the dermal layer, and the subcutaneous fat layer.

The epidermis is the most surface layer of the skin. Depending on its position and function, the epidermis is composed of several layers such as stratum corneum, transparent layer, granular layer, superficial layer and basal layer, and functions as protection, defense and secretion.

In addition, the dermis layer is located below the epidermis layer and is positioned adjacent to the basal layer to form the majority of the skin. The dermis layer is composed of water, proteins, saccharides, mucopolysaccharides, minerals, inorganic salts, And a reticular layer containing elastin and a matrix (a reservoir of water), elastic fibers that give skin elasticity, collagen, which is the collagen fibers associated with the wrinkles of the skin.

Finally, the subcutaneous fat layer is located between the dermis, muscles and bones, and contains a large amount of fat. It constitutes the lowest layer of the skin and spreads evenly throughout the body, absorbing external pressure and shock due to elasticity maintenance and buffering action It not only prevents damage to the inside of the body but also prevents the loss of body heat and maintains body temperature.

On the other hand, chronic inflammatory diseases of the hair follicle gland are various skin changes such as cotton papules, papules, blisters, nodules, and false cysts, resulting in a concave scar or enlarged scars. Acne is a disease that occurs in the face, neck, chest, where sebaceous glands are gathered, and inflammation occurs in sebaceous glands attached to hair follicles. Acne usually appears in puberty, but acne occurring in puberty continues until after age 25, or in the late 20s, is called adult acne. Adult acne is more likely to leave scar rather than adolescence and early treatment is important.

Although the cause of acne is not known precisely, genetic factors and environmental factors are known to be associated with the colonization of acne bacteria and sebaceous glands, and it is known that acne is caused by excessive oil, It is known that irritation, stress, and excessive sweating can make or exacerbate acne.

It is divided into the medicine to treat acne, the medicine to eat, and the surgical treatment.

Most of these drugs have a direct sterilization effect against acne bacteria, and the medicine to eat has antibiotics and retinoids that sterilize acne bacteria and reduce inflammation. Retinoids are known to cause fetal anomalies during pregnancy.

On the other hand, there are surgical treatments for symptomatic areas such as surgical treatment, acne extrusion treatment, and peeling. If acne is squeezed excessively, scarring is often left after treatment, so acne scar treatment is necessary.

The high frequency current causes very little ion motion because of the very short amplitude of vibration when the body tissue is energized, and does not cause electrochemical reaction or electrolysis phenomenon. When high-frequency electrical energy is applied to tissue, molecules of the tissue vibrate and rub against each other whenever the direction of current changes, generating biothermal heat. In addition, these high frequencies do not stimulate the sensory nerve and motor nerve unlike other current types, do not cause discomfort or contraction in the human body, can generate heat energy, and this heat energy also enhances the function of the cells An additional effect of increasing blood flow can be induced. In the treatment of dermatological disorders, high frequency is widely used in various fields such as acne treatment, wrinkle lifting, scar treatment by acne, injection of filler.

In the conventional high-frequency treatment system for skin treatment, there is a problem that the physician causes the patient to suffer from high-frequency radiation error in performing the high-frequency treatment to the patient.

Korean Patent Laid-Open No. 10-2015-0007938 " Skin treatment apparatus " is disclosed.

The handpiece is provided with a holder part and a signal for supplying a signal to the holder part. The handpiece is attached to the holder part, . The treatment unit includes a surgical needle inserted into the skin; A support plate connected to the surgical needle and restricting movement of the user to the skin; And an insertion plate connected to the support plate and mounted to the holder portion. To prevent risks such as the transmission of germs, the treatment unit used is discarded and replaced with a new one. In order to replace the treatment unit with a new one after the treatment, the small-sized treatment unit must be separated with a tweezers or the like, and a new one must be replaced. This is very inconvenient and the fine pin is damaged or contaminated during the replacement process.

Korean Patent Publication No. 10-2015-0007938

Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made in order to solve the problems of the prior art, and it is an object of the present invention to provide a cartridge replacement device, It is an object of the present invention to provide a high frequency handpiece for treating an acne disease, which can solve the difficulty, enable a more hygienic replacement work, and prevent the accidental loss by preventing the needle from being lost.

The above object of the present invention can be achieved by a light emitting device comprising: a body; A high frequency generator mounted on one side of the main body, the high frequency generator comprising a high frequency control board and a high frequency power connected to the high frequency control board; A high frequency handpiece comprising a handle having one end connected to the high frequency generator and having an opening at the other end, a needle cartridge detachably coupled to one side of the handle and having microneedles inserted into the skin and transmitting high frequency waves; Wherein the micro needle cartridge comprises: a holder having openings on both sides and a passage formed therein; A needle assembly coupled to one side of the holder and having the microneedles formed therein; And a connector coupled to the other opening of the holder and connected to one side of the needle assembly and having a fitting portion on the other side.

The present invention also relates to an acne treatment system for treating an acne disease, comprising: an operation of a microneedle high frequency system for treating an acne disease in which the operator touches the high frequency handpiece to the skin to be treated and applies a high frequency voltage to the high frequency generator; ≪ / RTI >

According to the present invention, it is possible to easily replace the cartridge formed with the micro-needle from the handle so that the cartridge can be replaced with a new one, the difficulty of replacing the micro-needle can be eliminated, The risk can be prevented and the loss of the micro needle can be prevented.

1 is a perspective view of a microneedle high frequency system for treating acne disease according to an embodiment of the present invention,
FIG. 2 is a perspective view showing the inside of FIG. 1,
3 is a perspective view illustrating a high frequency handpiece according to an embodiment of the present invention,
4 is an exploded perspective view showing a high frequency handpiece according to an embodiment of the present invention,
FIG. 5 is a perspective view partially enlarged in FIG. 3,
FIG. 6 and FIG. 7 are partial cross-sectional views showing the inside of a high frequency handpiece according to an embodiment of the present invention;
FIG. 8 is a micro-needle high frequency system for treating acne disease according to an embodiment of the present invention. FIG. 8 is a photograph of the skin observed after acne treatment of the acne-induced rats using Dermal scars using immunohistochemical staining ,
FIG. 9 shows the results of treatment of the acne disease microneedle system according to one embodiment of the present invention by pulsed light irradiation alone at 1, 3, and 5 days after acne induction using a rabbit ear acne model, Photographs taken with a pulsed light irradiation and observed with a scanning microscope.
FIG. 10 is a photograph showing the change of PPAR gamma (PPAR gamma) by immunohistochemical stain after acne-induced dermoscopy using a rabbit ear acne model,
FIG. 11 is a photograph showing changes in tumor necrosis factor alpha, TNF-α, or TNF using anthera-3D through immunohistochemical staining after acne induced by using a rabbit ear acne model.
FIG. 12 is a graph showing the results of visual observation, H & E staining, oil-red staining and dermoscopic observation of each sample after 7 days of acne induction using a hairless rat model,
FIG. 13 is a photograph showing the results of immunohistochemical staining for observing the change of fatty acid synthesis protein (FAS) in the sebaceous glands after acne induced using a hairless rat model,
14 is a photograph showing the result of immunohistochemical staining for confirming the decrease of the sebaceous proliferative marker ki-67 after acne induced using a hairless mouse model.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. It should be noted that the same components are denoted by the same reference numerals as possible in the accompanying drawings. Further, the detailed description of known functions and configurations that may obscure the gist of the present invention will be omitted.

Furthermore, the terms and words used in the present specification and claims should not be construed to be limited to ordinary or dictionary terms, and the inventor should understand the concept of the term The present invention should be construed as meaning and concept consistent with the technical idea of the present invention.

1 to 7, a microneedle high frequency system for treating an acne disease according to an embodiment of the present invention includes a main body B; A high frequency generator 800 mounted on one side of the main body B and composed of a high frequency control board 820 and a high frequency power 840 connected to the high frequency control board 820; A handle 100 having one end connected to the high frequency generator 800 and having an opening formed at the other end thereof and a microneedle 100 inserted into one side of the handle 100 and inserted into the skin, And a high frequency handpiece (R) composed of a needle cartridge (2) having a needle roller (32) formed thereon, the needle cartridge (2) comprising: a holder (22) having both open sides and a passage formed therein; A needle assembly (3) coupled to one side of the holder (22) and having the micro needle (32) formed therein; And a connector (4) coupled to the other opening of the holder (22) and connected to one side of the needle assembly (3) and having a fitting part on the other side.

The main body B includes a lower base B-1, a cover B-2 coupled to the upper portion of the lower base B-1, and a main case B- -3) (not shown).

A liquid crystal screen B-4 having a touch screen is formed on one side of the cover B-2 of the main body. The liquid crystal display part is a touch screen, and various menus for controlling the high frequency treatment are displayed. By touching various menus, on / off is controlled, and various functions are selected and used. On one side of the cover B-2, a switch unit B-22 composed of ON / OFF control and an emergency switch is formed. If an emergency occurs during use, the emergency switch is operated to stop the procedure, thereby minimizing the risk of a safety accident.

3 and 4, one end of the high frequency handpiece R is connected to the high frequency generator 800 through a power cable 140 and is cylindrical in shape to be held by hand, A handle 100 formed with a hole; And a needle cartridge (2) fitted to one side of the handle (100) and provided with a needle (32) which is supplied with power and outputs high frequency to the skin.

The handle 100 has a predetermined length and has a cylindrical shape and has a streamlined shape so that the grip feeling is good and it is not slippery. In addition, the handle 100 can be separated into two parts, and parts such as a conductor 120 and a power plug 5 for supplying power to the inside are incorporated.

The cap 7 is coupled to the front end of the handle 100 so that the engaging portion 24 of the needle cartridge 2 is fitted. A stopper 130 inserted into the fitting slot 242 is formed on the inner circumferential surface of the cap 7.

The needle cartridge 2 can be detached and coupled with the handle 100 and is detachable so that the needle cartridge 2 is used after one use and replaced with a new one.

The needle cartridge 2 includes a holder 22 having both open sides and a passage formed therein; A needle assembly (3) coupled to one side of the holder (22) and having a micro needle (32) inserted into the skin; A connector (4) coupled to the other opening of the holder (22) and connected to one side of the needle assembly (3) and having a fitting part (42) on the other side; And a power plug 5 fitted to the fitting portion 42 of the connector 4 so as to be detachable and coupled to the handle 100 to supply power.

The holder 22 has a needle insertion hole 26 at one side thereof for inserting the needle assembly 3 and a coupling portion 24 at the other side thereof with a through hole 29 for inserting the connector 4 therein.

The holder 22 is formed into a cylindrical shape by coupling the two divided first and second bodies 221 and 222 to each other and is formed into a cylindrical shape having a smaller diameter from the front end where the needle insertion hole 26 is formed to the rear end where the coupling portion 24 is formed The tapered shape is formed so as to have a larger diameter, so that the shape is easily grasped by the thumb and the index finger.

The engaging portion 24 is formed in a cylindrical shape at the rear end of the holder 22 and is formed to have a diameter smaller than that of the rear end of the holder 22. The engaging portion 24 is recessed concavely in an ' And is engaged with the fastening portion 110 of the handle 100 to be engaged.

A stopper 130 inserted into the fitting slot 242 is formed on the inner circumferential surface of the cap 7.

A space is formed on the inner side of the first and second bodies 221 and 222, and a guide step 28 is formed on the cut surface at the edge of the space.

The guide step 28 is a part where the outer periphery of the needle assembly 3 to be described later is in close contact with the needle assembly 3 and the needle assembly 3 is stably fixed to the guide step 28 .

The needle assembly 3 is a thin metal plate having conductivity. A through hole 305 is formed at one side coupled to the connector 4, and a sharp needle 32 is formed at the other end.

The needle assembly 3 is divided into a plurality of steps so that the width of the needle assembly 3 is narrowed from the opposing portion of the micro needle 32 to a plurality of stages. A guide step 28 corresponding to the step of the needle assembly is formed in the holder 22 And are tightly coupled with each other. A first step 301, a second step 302, and a third step 303 so that the width of the first step 301, the second step 302, and the third step 303 may be narrowed from the opposed portion of the micro needle 32 to one or two. The first step 301 and the second step 302 are shaped to fit the guide step 28 of the holder 22.

A through hole 305 is formed in one side of the needle assembly 3 through a holder 22 and through which an engaging shaft 223 penetrating through the connector 4 is inserted and a pin formed in the holder 22 is fitted to the other side A fixing hole 307 is formed.

Therefore, after the needle assembly 3 is engaged with the holder 22 and the connector 4 is engaged, the needle assembly 3 can be securely fixed so as not to be shaken.

The microneedles 32 are formed so as to be inserted into the skin and are made of a conductive material so that a high frequency signal can be applied to the microneedles 32 from the outside to be transmitted to the skin.

The micro needles 32 may be formed as one, or a plurality of micro needles 32 may be formed. Fig. 4 shows three micro needles 32, and Fig. 5 shows one micro needle 32 and three micro needles 32. Fig. The microneedles 32 are insulated from the rest of the microneedles except for the tip portion of the microneedles which are inserted into the skin and transmit high frequencies to the skin, thereby preventing unnecessary skin damage at the time of high frequency treatment.

The connector 4 is a conductive rod having a conductive shape. One side of the connector 4 is vertically cut to form a mounting surface 41, and a plurality of cut-away pieces 421 are arranged in the circumferential direction on the other side. So that the fitting portion 42 is formed.

A needle assembly (3) is closely attached to a mounting surface (41) of the connector (4).

A screw may be inserted through the mounting surface 41 and a part of the screw may be coupled to the needle assembly 3 to be integrated.

One end of the power plug 5 is coupled to the fitting portion 42 of the connector 4 while the other end of the power plug 5 is connected to the conductor 120 by fitting.

In the middle of the power plug 5, the outer diameter is enlarged to form the enlarged portion 52, and a part of the enlarged portion 52 is formed flat to form the groove portion 521. The groove portion 521 is inserted into the conductor 120 to serve as a latching jaw, so that the power plug 5 can be prevented from being unintentionally lifted off.

Hereinafter, the operation of the present invention will be described.

The connector 4 is inserted into one side of the first and second bodies 221 and 222 constituting the holder 22 and the needle assembly 3 is inserted into the holder 22 on the other side, The two bodies 221 and 222 are coupled together and the needle assembly 3 and the connector 4 are all screwed together to assemble the needle cartridge 2. [

The needle cartridge 2 thus assembled is fitted into the fastening portion 110 of the handle 100. At this time, in order to improve the fixing force, the cap (7) is attached to the tip of the handle (100).

Meanwhile, the micro needle 32 is protected by the plug 8 attached to one side of the holder 22 in order to prevent an accident because the micro needle 32 is exposed to the outside and to prevent the micro needle 32 from being damaged .

The micro needle 32 is inserted into the skin by gripping the handle 100 after removing the stopper 8, and then treated with high frequency.

After the operation is finished, the holder 22 is rotated so that the stopper 130 is released from the fitting slot 242, and then the holder 22 is pulled outward to separate the needle cartridge 2 from the handle 100.

Therefore, the used needle cartridge 2 can be discarded and the new needle cartridge 2 can be combined with the handle 100 to be used, thereby assuring hygienic and safety.

A body according to the present invention; A high frequency generator mounted on one side of the main body, the high frequency generator comprising a high frequency control board and a high frequency power connected to the high frequency control board; A high frequency handpiece comprising a handle having one end connected to the high frequency generator and having an opening at the other end, a needle cartridge detachably coupled to one side of the handle and having microneedles inserted into the skin and transmitting high frequency waves; And a step of contacting the high frequency handpiece with skin to be treated by a practitioner using a microneedle high frequency system for treating an acne disease and applying a high frequency voltage to the high frequency generating unit to operate the acne disease treatment system.

In order to improve the acne disease treatment effect of the microneedle high frequency system for treating acne disease of the present invention, it is effective to treat pulsed light irradiation (IPL) using an optical air pressure treatment unit (not shown). The optical air pressure treatment unit is composed of a pulse light irradiation unit and a light-guiding handpiece. After the operation of the high-frequency handpiece according to the present invention is completed, the light- And the pulse light irradiation voltage is applied to the generation portion.

In order to test the acne treatment performance of the microneedle high frequency system for treating acne diseases according to the present invention, skin stability was evaluated using the skin of the rats, and the result of confirming skin irritation or damage after high frequency treatment was shown in FIG. 8 shows a result obtained by changing the level of the high frequency energy to low (level 1), medium (level 5) and high (level 10), and treating the duration to 50 ms, 400 ms and 1000 ms, respectively. As shown in Fig. 8, irreversible skin irritation or damage was not observed in the high-frequency treatment.

In FIG. 9, the state of the acne strain in the untreated group is [a], the state of the acne strain in the group of one pulse light irradiation treatment (5 levels, duration 1000 ms, shot 3 times) is [b] After irradiating (10 levels of energy, 1000ms, 3 times), treatment with pulse light (10 levels, duration 1000ms, shot 3 times) The condition of a group of acne strains is [c]. B] and a microneedle high frequency system for treating acne disease according to the present invention, compared to the acne strain condition of the group [a], which has not undergone any treatment, by pulsed light irradiation In the group [c] treated with the pulse light irradiation after treating the high frequency using the microneedle high frequency system for treating acne disease of the present invention, Strain destruction was clearly observed. That is, it can be seen that the high-frequency irradiation is effective for treating acne, and the high-frequency irradiation and the pulse irradiation treatment are more effective for acne treatment.

Using a rabbit ear acne model, P. acnes was inoculated and acne was induced. At 1, 3, 5, and 7 days after induction, pulsed light irradiation alone, RF and pulsed light irradiation. We also used DSLR and dermascope ( TM ) to evaluate the improved acne scar and pore status after the procedure, and use the AnTERA 3D TM equipment Safety and acne treatment efficacy were evaluated.

Experimental conditions were as follows: the pulsed light irradiation alone treatment and the microneedle high frequency system for acne disease treatment of the present invention were treated with high frequency waves, and then the pulsed light irradiation treatment was used. On the other hand, the needle gauge used in high frequency treatment and pulsed light irradiation is 1.2 mm and 1.5 mm.

Experimental group
Experimental conditions
Classification Device treatment condition G1 P. acnes inoculation Untreated group X G2
P. acnes inoculation
Positive control group
[Continuous application of oleic acid]
X
G3 Pulsed light irradiation alone treatment Pulsed light irradiation: 3 pulse, 5 level, duration 1000 ms G4 RF and pulsed light irradiation combination treatment RF: 5 level, 400 ms
Pulsed light irradiation: 3 pulse, 5 level, duration 1000 ms

As shown in the above table, acne strain was inoculated into four groups of rabbit ear acne induced model, and the efficacy of RF and pulse irradiation treatment for acne strains was evaluated. 10 and 11 show the results of immunohistochemistry to confirm the reduction of inflammatory factors in the above four groups.

FIG. 10 is a graph showing the results of a gene transcription assay for accelerating the synthesis of an anti-inflammatory mediator in a group treated with high frequency using a microneedle high frequency system for treating acne disease according to the present invention, And a decrease in the factor PPAR Gamma (Peroxisome proliferator-activated receptor gamma, PPAR gamma).

FIG. 11 is a graph showing the relationship between the tumor necrosis factor-alpha and the number of tumor necrosis factor-alpha in the group treated with high-frequency using a microneedle high frequency system for treating acne disease according to the present invention, TNF-a, or TNF). Therefore, it can be understood that the inflammatory factor was decreased when the high frequency was treated using the microneedle high frequency system for acne disease treatment of the present invention and then the pulse light irradiation treatment was performed in comparison with the pulsed light irradiation alone group.

As a result of evaluating skin stability and efficacy using a hairless rat model, high frequency was treated using a microneedle high frequency system for acne disease treatment of the present invention as compared to a pulsed light irradiation single treatment group, and pulsed light irradiation (FAS) and sebaceous hyperplasia marker (ki-67) in the sebaceous glands. As in the rabbit ear acne induction in the unarmed rats, the appearance of the acne strain was observed immediately after 1 day, 4 days, and 7 days after the inoculation.

Experimental conditions were classified into single pulse treatment (divided into low and high) and RF and pulse irradiation treatment. On the other hand, the needle gauge used in the RF and pulsed light irradiation procedure is 1.2 mm.

Experimental group
Experimental conditions
Classification Device treatment condition G-1 P. acnes inoculation Untreated group X G-2
P. acnes inoculation
Pulsed light irradiation single treatment (low) Pulsed light irradiation: 3 pulse, 5 level, duration 1000 ms
G-3 Pulsed light irradiation single treatment (high) Pulsed light irradiation: 3 pulse, 9 level, duration 1000 ms G-4
RF and pulsed light irradiation combination treatment
RF: 5 level, 400 ms
Pulsed light irradiation: 3 pulse, 5 level, duration 1000 ms

FIG. 12 is a photograph showing the results of visual acuity observation, hematoxylin and eosin staining, observation with a dermoscope, and analysis of Solvent Red 27, Sudan Red 5B, CI 26125, C 26 H 24 N 4 O, Oil Red O).

Although sebaceous glands were clearly observed in the untreated group (G-1), changes in sebaceous gland were observed in the pulsed light irradiation single treatment group (G-2 and G-3) (G-4) treated with high-frequency waves and pulsed-light irradiation were observed in comparison with pulsed-light irradiation alone treatment group.

FIG. 13 shows the result of immunohistochemistry to confirm the decrease of FAS in the sebaceous glands of the four groups, and FIG. 13 shows the results of immunohistochemical staining of the sebaceous proliferation marker ki-67 The results of immunohistochemical staining for confirming the reduction were shown in Fig. As can be seen from Figs. 13 and 14, in comparison with the pulsed light irradiation single treatment group (G-2 and G-3), high frequency is treated using the microneedle high frequency system for treating acne disease of the present invention, (FAS) and sebaceous hyperplasia marker (ki-67) were reduced in the group (G-4)

While the present invention has been described in connection with what is presently considered to be practical exemplary embodiments, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, It will be understood. It is therefore to be understood that the above-described embodiments are illustrative in all aspects and not restrictive.

B: main body 800: high frequency generating section
820: High frequency control board 840: High frequency power
R: High frequency handpiece
2: Needle cartridge 3: Needle plate
4: connector 22: holder
28: Guide step 32: Micro needle
24: engaging portion 26: needle insertion hole
100: handle 130: stopper
5: Power plug

Claims (8)

main body;
A high frequency generator mounted on one side of the main body, the high frequency generator comprising a high frequency control board and a high frequency power connected to the high frequency control board;
A handle coupled to the high frequency generating part at one end thereof and having an opening at the other end thereof and a fastening part at an end of the opening;
And a needle cartridge detachably coupled to one side of the handle and having needle needles inserted into the skin and having microneedles for transmitting a high frequency,
Wherein the needle cartridge comprises:
A holder having a needle insertion hole through which the needle assembly is inserted at one side and a coupling portion at which the through hole is formed at the other side to insert a connector;
A needle assembly coupled to one side of the holder and having the microneedles formed therein;
And a connector coupled to the other opening of the holder and connected to one side of the needle assembly and having a fitting portion at the other side,
The connector
A mounting surface is formed so as to be in contact with the needle on the outer circumferential surface of the other side,
And a power plug detachably coupled to the connector and coupled to the handle to supply power,
The power plug
And an enlarged portion having an outer diameter enlarged is formed at an intermediate portion of the connector, and a groove portion for inserting and fixing the conductor into the conductor is formed in the enlarged portion, The micro-needle high frequency system for treating an acne disease.
delete The method according to claim 1,
Wherein the coupling part of the holder is formed with a fitting slot having an " a " shape on the outer circumferential surface, and is engaged with the fastening part of the handle.
The method according to claim 1,
The handle
Wherein the needle cartridge includes a cap which is overlaid on the fitting end,
And a stopper inserted into the fitting slot is formed on an inner circumferential surface of the cap.
delete The method according to claim 1,
The microneedle high frequency system for treating acne disease according to claim 1, wherein the needle assembly is a thin metal plate having conductivity, and one or more needles are formed on one side of the needle assembly and connected to the connector.
The method according to claim 1,
Wherein the needle assembly is divided into a plurality of steps so as to be narrowed in width from an opposite portion of the micro needle to multiple ends,
Wherein the holder is provided with a guide step corresponding to a step of the needle assembly.
The method of any one of claims 1, 3, 4, 6, and 7,
A method of operating a microneedle high frequency system for treating an acne disease, wherein the high frequency handpiece is contacted with a skin to be treated by a practitioner using a microneedle high frequency system for treating acne disease, and a high frequency voltage is applied to the high frequency generator.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021045448A1 (en) * 2019-09-02 2021-03-11 아주대학교산학협력단 Optical therapy device using ultrasonic waves and bubble generation material injection device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101188710B1 (en) * 2011-04-18 2012-10-15 주식회사 루트로닉 Needle tip of high-frequency therapy and high-frequency therapy apparatus using the same
KR20150007938A (en) 2013-07-12 2015-01-21 주식회사 고운세상코스메틱 Device for medical skin care
KR20160133686A (en) * 2015-05-13 2016-11-23 주식회사 고운세상코스메틱 Needle for medical skin care
KR101714756B1 (en) * 2015-09-15 2017-03-09 주식회사 파나시 High-frequency handpiece for with needle cartridge

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10667830B2 (en) * 2015-04-13 2020-06-02 Bellus Medical, Llc Collagen stimulation device and methods
KR101709733B1 (en) * 2015-10-22 2017-03-08 제이에스케이바이오메드 (주) injector for medicinal fluid injection with multi-needles
KR101828589B1 (en) * 2016-07-04 2018-02-13 주식회사 파나시 High-Frequency Handpiece for Skin Surgery

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101188710B1 (en) * 2011-04-18 2012-10-15 주식회사 루트로닉 Needle tip of high-frequency therapy and high-frequency therapy apparatus using the same
KR20150007938A (en) 2013-07-12 2015-01-21 주식회사 고운세상코스메틱 Device for medical skin care
KR20160133686A (en) * 2015-05-13 2016-11-23 주식회사 고운세상코스메틱 Needle for medical skin care
KR101714756B1 (en) * 2015-09-15 2017-03-09 주식회사 파나시 High-frequency handpiece for with needle cartridge

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021045448A1 (en) * 2019-09-02 2021-03-11 아주대학교산학협력단 Optical therapy device using ultrasonic waves and bubble generation material injection device

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