KR101833729B1 - a filter of injection device for medical use - Google Patents

a filter of injection device for medical use Download PDF

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KR101833729B1
KR101833729B1 KR1020170151221A KR20170151221A KR101833729B1 KR 101833729 B1 KR101833729 B1 KR 101833729B1 KR 1020170151221 A KR1020170151221 A KR 1020170151221A KR 20170151221 A KR20170151221 A KR 20170151221A KR 101833729 B1 KR101833729 B1 KR 101833729B1
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filter
injection
filter housing
injection liquid
liquid
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Korean (ko)
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이정민
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이정민
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165Filtering accessories, e.g. blood filters, filters for infusion liquids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3145Filters incorporated in syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0429Red blood cells; Erythrocytes
    • A61M2202/0437Blood stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/75General characteristics of the apparatus with filters
    • A61M2205/7545General characteristics of the apparatus with filters for solid matter, e.g. microaggregates

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The present invention relates to a filter for filtering an injection liquid for a medical injection device. The filter can filter out lumps in a target substance injection liquid such as stem cells. According to an embodiment of the present invention, the filter for filtering an injection liquid for a medical injection device includes: a first filter housing which has injection liquid injection holes formed therein in a through shape, has a first screw unit formed on a side of the outer periphery, and has a filter space for filtering the injection liquid; an injection liquid filter member which is mounted on the filter space, filters the lumps in an arbitrary size in the injection liquid, and only lets the target substances pass therethrough by using target substance passing holes formed thereon; a supporter which has injection liquid discharging holes linked to the injection liquid injection holes, presses the injection liquid filter member mounted in the filter space, and prevents the injection liquid filter member from being released; and a second filter housing which has a second screw unit corresponding to the first screw unit on the inner periphery, supports the flange of the supporter when screw-coupling the first and second screw units, and prevents the supporter from being released from the first filter housing.

Description

의료 주입장치용 주입액 여과필터{a filter of injection device for medical use}BACKGROUND OF THE INVENTION 1. Field of the Invention [0001]

본 명세서는 여과필터에 관한 것으로, 보다 구체적으로 설명하면, 줄기세포 등의 목적물질 주입액에 포함되는 덩어리 등을 여과하기 위한 의료 주입장치용 주입액 여과필터에 관한 것이다.The present invention relates to a filtration filter, and more specifically, to a filtration filter for a medical fluid injecting apparatus for filtering lumps and the like contained in a target substance infusion liquid such as stem cells.

일반적으로, 인체 또는 동물의 근육이나 혈관 속으로 주사액을 일정한 농도로 주입하기 위해서는 주입장치가 사용된다.Generally, an infusion device is used to infuse injections at a constant concentration into the muscles or blood vessels of a human or animal.

이때, 주사액이란 식염수(또는 인체 튜여가 가능한 링거액, 영양수액 등을 말함)에 특정의 약액이나 줄기세포와 같은 목적물질을 혼합시킨 것을 의미한다.In this case, the injectable solution means a mixture of saline solution (or Ringer's solution or nutrient solution capable of human tearing) with a target drug such as a specific drug solution or stem cell.

또한, 약액은 액체상태의 약액, 2종 이상의 약을 혼합한 액체상태의 약액, 에멀젼이나 슬러리 형태의 약액중 어느 하나의 형태로 이루어질 수 있다. Further, the chemical liquid may be in the form of any one of a liquid chemical, a liquid chemical mixed with two or more chemicals, and a chemical liquid in emulsion or slurry form.

줄기세포는 자가증식과 분화가 가능한 세포를 의미하며, 크게 배아 줄기세포와 성체 줄기세포로 구분된다. 이중 성체 줄기세포는 우리 몸의 지방조직과 골수 조직 등에 다량 존재하는 것으로 밝혀지고 있다.Stem cells are cells capable of autolabelling and differentiation, and are largely classified into embryonic stem cells and adult stem cells. Double adult stem cells are found to be abundant in the adipose tissue and bone marrow tissue of our body.

현재 병원에서 쉽게 사용가능한 세포는 지방조직을 채취한 후, 이를 효소 처리한 후 얻어지는 간질혈관분획세포, 간질혈관분획세포를 한번 더 정제한 후 얻을 수 있는 지방유래줄기세포, 골수에서 골수액을 추출한 후 배양과정을 거쳐서 얻을 수 있는 골수유래 중간엽-줄기세포 등으로 구분된다.Cells that can be easily used in hospitals nowadays are those obtained by collecting adipose tissue, enzymatically treating the cells, obtaining the stem cells obtained from the epileptic vessels, the adipose-derived stem cells obtained after further purification of the epileptogenic blood cells, And bone marrow-derived mesenchymal stem cells that can be obtained through a post-incubation process.

줄기세포는 추출 과정, 또는 추출 완료한 후, 물과의 비중차로 인해 물 아래로 쉽게 침강(침전)되고, 플라스틱에 부착성이 높으며, 서로 엉켜 붙어 잘 응고되는 특성을 갖게 된다.After the extraction process or extraction, the stem cells easily settle down (precipitate) under water due to the difference in specific gravity with water, have a high adherence to plastic, and have a property of coagulating well with each other.

이러한 줄기세포 특성으로 인해 추출된 줄기세포를 인체에 투여할 경우 상당한 주의를 기울이지 않을 경우, 투입과정에서 상당한 세포 손실을 초래할 수 있고, 결과적으로 치료 효과가 감소될 수 있다.Due to such stem cell characteristics, if the extracted stem cells are administered to the human body without paying heedful attention, it may lead to considerable cell loss during the injection process, and as a result, the therapeutic effect may be reduced.

또한 줄기세포가 덩어진 상태 또는 고농도로 투여될 경우 혈관을 막아 혈전증이 발생될 수 있고, 알러지가 유발될 수 있다.,In addition, when the stem cells are administered in a lump state or at a high concentration, thrombosis may be caused by blocking blood vessels, and allergy may be induced.

또한, 에멀젼, 슬러리 형태의 물질(세포 또는 용액에 용해되지않은 형태의 물질)을 투입할 경우, 안전을 위해서 여과 등의 추가 과정이 필요한데, 이러한 추가과정은 조금만 부주의해도 주입되는 목적물질이 쉽게 손상을 받아 치료 효과가 떨어질 수 있다.In addition, when an emulsion or a slurry-like substance (a substance that is not dissolved in a cell or a solution) is added, an additional process such as filtration is required for safety. And the treatment effect may be lowered.

이러한 위험성이 있음에도 불구하고, 줄기세포를 주입하기 위한 주입장치의 개발은 미미한 상태이다. Despite these risks, the development of infusion systems for injecting stem cells is marginal.

도면에는 미 도시되었으나, 종래 기술에 의한 의료용 주입장치(대한민국 등록특허공보 제1640481호)는Although not shown in the drawings, a medical implanting apparatus according to the prior art (Korean Patent Registration No. 1640481)

주입액을 수용하기 위한 공간이 내부에 형성되고, 하부에 주입액 유출포트가 형성되는 컨테이너(10);A container (10) in which a space for receiving the injection liquid is formed, and a injection liquid outflow port is formed in the lower part;

주입액 유출포트에 연장 결합되고, 주입액을 여과하기 위한 주입액 여과필터(40);An injection liquid filtration filter (40) extended to the injection liquid outlet port and for filtering the injection liquid;

주입액 여과필터 하부에 연장 연결되고, 주입액을 주입하기 위한 이동 유로를 제공하는 가이드 튜브(70);A guide tube (70) extended from the bottom of the injection liquid filtration filter and providing a flow path for injecting the injection liquid;

외부공기가 유출입되는 정도를 조절하기 위한 제1수위조절포트(18)와, 주입액 여과필터 상부에 형성되는 제2수위조절포트(44)를 서로 연통되게 연결하는 주입액 수위 조절관;을 구비하되,A water level control pipe for connecting the first water level control port 18 for controlling the degree of the outside air to the outside and the second water level control port 44 formed above the water level filtration filter to communicate with each other, However,

주입액 여과필터(40)는 주입액을 여과하기 위한 여과 공간이 형성되는 필터하우징(41)과, 필터하우징(41) 내에 설치되고, 주입액을 여과하기 위한 주입액 여과재(45)를 구비한다.The injection liquid filtration filter 40 has a filter housing 41 in which a filtration space for filtering the injection liquid is formed and an injection liquid filtering material 45 installed in the filter housing 41 for filtering the injection liquid .

전술한 주입액을 여과시키는 과정에서 주입액 내에 포함된 덩어리 물질을 여과하고, 줄기세포 등의 목적물질은 통과시키기 위한 주입액 여과재(45)는 망사구조의 나일론재로 형성된다.In the process of filtrating the above-mentioned injection liquid, the lump material contained in the injection liquid is filtered, and the injection liquid filter material 45 for passing a target material such as stem cells is formed of a nylon material having a mesh structure.

이로 인해, 종래 기술의 주입액 여과재(45)는 초기에는 줄기세포의 덩어리 를 기준치에 부합되도록 여과할 수 있다.As a result, the injection filtrate material 45 of the prior art can initially be filtered so that the mass of the stem cells conforms to the reference value.

이와 반면에, 임의시간 경과후에는 주입액 여과재(45)의 망사구조가 나일론재의 특성 또는 필터하우징(41)에 주입액을 주입시키는 주사기 압력에 의해 쉽게 손상되거나, 또는 변형될 수 있어 기준치를 초과하는 줄기세포 덩어리가 주입액 여과재(45)를 쉽게 투과할 수 있다.On the other hand, after a certain amount of time has elapsed, the mesh structure of the infusion filtration media 45 may be easily damaged or deformed by the nature of the nylon material or the syringe pressure that injects the infusion fluid into the filter housing 41, The stem cell mass can easily penetrate the infusion fluid filter medium 45.

즉, 나일론재로 형성된 주입액 여과재(45)를 투과하는 줄기세포의 농도가 불균일할 경우 목적물질을 인체에 주입시 치명적인 의료사고가 발생될 수 있고, 인체에 대한 줄기세포 주입에 대한 신뢰성 또는 안전성이 현저하게 떨어지는 문제점을 갖게 된다.That is, when the concentration of the stem cells passing through the infusion liquid filter material 45 formed of nylon material is not uniform, a catastrophic medical accident may occur when the target material is injected into the human body, and the reliability or safety This leads to a problem that falls significantly.

대한민국 등록특허공보 제10-1640481호(2016.7.12.등록)에 의료용 주입장치가 게시되어 있다.Korean Patent Registration No. 10-1640481 (registered on July 12, 2016) discloses a medical injection device.

따라서, 본 명세서의 실시예는, 줄기세포 등의 목적물질 주입액을 필터하우징에 주입시키는 주사기 압력에 무관하게 주입액에 포함되는 덩어리 등을 균일하게 여과할 수 있도록 한 의료 주입장치용 주입액 여과필터와 관련된다.Therefore, the embodiment of the present invention is an injection filtration device for a medical injection device capable of uniformly filtering lumps and the like contained in an injection liquid irrespective of a syringe pressure for injecting a target substance injection solution such as stem cells into a filter housing Filter.

본 명세서의 실시예는, 농도가 일정하도록 추출시킨 줄기세포 등의 목적물질을 인체에 주입시킬 수 있어 신뢰성 및 안전성을 확보할 수 있도록 한 의료 주입장치용 주입액 여과필터와 관련된다.The embodiments of the present invention relate to an injection liquid filtration filter for a medical infusion device capable of injecting a target material such as stem cells extracted at a constant concentration into a human body to ensure reliability and safety.

상기 및 기타 본 명세서의 목적을 달성하기 위하여 본 명세서의 일 실시예에 따르면,In order to achieve the above and other objects of the present disclosure, according to one embodiment of the present disclosure,

내부에 주입액 주입공이 관통형성되고 외주연 일측에 제1나사부가 형성되며, 주입액을 여과하기 위한 여과공간이 형성되는 제1필터하우징;A first filter housing through which an injection solution injection hole is formed, a first screw portion is formed on an outer peripheral side of the first filter housing, and a filtration space for filtering the injection solution is formed;

상기 여과공간에 안착되고, 주입액중 임의크기의 덩어리를 여과하며 목적물질만을 투과시키기 위한 목적물질 통과공이 형성되는 주입액 여과재;An injection liquid filter material which is seated in the filtration space and which forms a target material through hole for filtering a lump of an arbitrary size of the injection liquid and transmitting only a target material;

상기 주입액 주입공과 연통되는 주입액 배출공이 내부에 관통형성되며, 상기 여과공간에 장착되는 상기 주입액 여과재를 압착시켜 이탈되는 것을 방지하기 위한 서포터;A supporter for penetrating the infusion liquid discharge hole communicating with the infusion liquid infusion hole and preventing the infusion liquid filter material mounted on the filtration space from being squeezed out;

상기 제1나사부와 대응되는 제2나사부가 내주연에 형성되고, 상기 제1,2나사부를 나사결합시킬 경우 상기 서포터의 플랜지를 지지하여 상기 제1필터하우징으로부터 상기 서포터가 이탈되는 것을 방지하기 위한 제2필터하우징;을 구비하는 것을 특징으로 하는 의료 주입장치용 주입액 여과필터를 제공한다.A second threaded portion corresponding to the first threaded portion is formed on the inner circumference of the first filter housing and a flange of the supporter is screwed on the first and second threaded portions to prevent the supporter from being detached from the first filter housing And a second filter housing for injecting the liquid to be injected into the medical fluid injecting apparatus.

전술한 바와 같이 구성되는 본 명세서의 실시예는 아래와 같은 이점을 갖는다.The embodiment of the present invention configured as described above has the following advantages.

줄기세포 등의 주입액을 필터하우징에 주입시키는 주사기 압력에 무관하게 주입액에 포함되는 덩어리 등을 균일하게 여과시킴에 따라 주입액 여과필터에 대한 신뢰성 및 상품성을 향상시킬 수 있게 된다.It is possible to improve the reliability and merchantability of the injection liquid filtration filter by uniformly filtering the lumps contained in the injection liquid irrespective of the syringe pressure for injecting the injection liquid such as stem cells into the filter housing.

또한, 농도가 일정하도록 추출시킨 줄기세포 등의 목적물질을 인체에 주입시킬 수 있게 됨에 따라 목적물질의 농도가 불균일할 경우 발생되는 치명적인 의료사고의 발생을 예방할 수 있고, 줄기세포의 치료 효과를 극대화시킬 수 있게 된다.In addition, since a target substance such as stem cells extracted with a constant concentration can be injected into a human body, it is possible to prevent the occurrence of a fatal medical accident that occurs when the concentration of a target substance is uneven, and to maximize the therapeutic effect of stem cells .

도 1은 본 명세서의 바람직한 실시예에 따른 의료 주입장치용 주입액 여과필터의 사시도,
도 2는 도 1에 도시된 의료 주입장치용 주입액 여과필터의 분리사시도,
도 3은 도 1에 도시된 의료 주입장치용 주입액 여과필터의 단면도,
도 4는 도 1에 도시된 의료 주입장치용 주입액 여과필터의 사용상태도이다.
BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a perspective view of an infusion filtration filter for a medical infusion device according to a preferred embodiment of the present disclosure; Fig.
FIG. 2 is an exploded perspective view of the injection liquid filtration filter for the medical injection device shown in FIG. 1,
FIG. 3 is a cross-sectional view of the injection liquid filtration filter for the medical implantation device shown in FIG. 1,
4 is a use state diagram of the injection liquid filtration filter for the medical implantation apparatus shown in Fig.

이하, 첨부도면을 참조하여 본 명세서의 바람직한 실시예에 따른 의료 주입장치용 주입액 여과필터를 상세하게 설명한다.DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, the injection liquid filtration filter for a medical infusion device according to a preferred embodiment of the present invention will be described in detail with reference to the accompanying drawings.

도 1 내지 도 4를 참조하면, 본 명세서의 일 실시예에 따른 의료 주입장치용 주입액 여과필터는Referring to Figures 1 to 4, the infusion filtration filter for a medical infusion device according to one embodiment of the present disclosure comprises:

내부에 주입액 주입공(10)이 관통형성되고 외주연 일측에 제1나사부(11)가 형성되며, 주사기(도면부호 미 표기됨)를 통해 주입되는 주입액을 여과하기 위한 여과공간(12)이 형성되는 제1필터하우징(13);And a first screw portion 11 is formed on one side of the outer periphery of the filtration space 12. The filtration space 12 for filtering an injection liquid injected through a syringe (not shown) A first filter housing (13) in which the first filter housing (13) is formed;

여과공간(12)의 안착부에 안착되고, 주사기에 의해 주입되는 주입액중 임의크기의 덩어리는 여과시키되, 줄기세포와 같은 목적물질만을 투과시키기 위한 목적물질 통과공(14)(일 예로서, 80-200㎛직경을 갖도록 레이저에 의해 천공될 수 있음)이 형성되는 주입액 여과재(15);A target material passage hole 14 (for example, a bottom surface of the target material passage hole) for allowing only a target material such as a stem cell to pass through is filtered by a lump of an injection liquid injected by a syringe, An infusion liquid filter material 15 in which a laser can be perforated to have a diameter of 80 to 200 mu m);

주입액 주입공(10)에 연통되는 주입액 배출공(16)이 내부에 관통형성되고, 여과공간(12)에 장착되는 주입액 여과재(15)를 압착부(도면부호 미 표기됨)에 의해 압착시켜 이탈되는 것을 방지하기 위한 서포터(17);An infusion liquid discharge hole 16 communicating with the infusion liquid infusion hole 10 is formed in the interior of the filtration space 12 and the infusion liquid filter material 15 mounted on the filtration space 12 is sealed by a compression unit A supporter (17) for preventing separation by squeezing;

제1나사부(11)와 대응되는 제2나사부(18)가 내주연에 형성되고, 제1,2나사부(11,18)를 나사결합시킬 경우 서포터(17)의 플랜지(27)를 지지하여 제1필터하우징(13)으로부터 서포터(17)가 이탈되는 것을 방지하기 위한 제2필터하우징(19);을 구비한다.A second threaded portion 18 corresponding to the first threaded portion 11 is formed on the inner periphery and a flange 27 of the supporter 17 is supported when the first and second threaded portions 11, And a second filter housing (19) for preventing the supporter (17) from being detached from the filter housing (13).

이때 더욱 바람직한 실시예에 의하면, 전술한 주입액 여과재(15)는According to a more preferred embodiment at this time, the above-described infusion liquid filter medium 15

주입액 주입공(10)의 출구측에 장착되고, 목적물질 통과공(14)이 천공되는 여과판(24)(일 예로서, 내구성 및 내부식성을 갖도록 스테인레스스틸재로 형성될 수 있음);A filter plate 24 (for example, formed of stainless steel so as to have durability and corrosion resistance), which is mounted on the outlet side of the injection liquid injection hole 10 and in which the target material passage hole 14 is perforated;

여과판(24)이 회전되지않도록 받쳐 지지하고, 서포터(17) 상단의 결합편(17a)과 대응되는 결합공(20b)이 중앙에 관통형성되는 원통형태의 여과판 받침구(20);를 구비할 수 있다.And a cylindrical filter plate support 20 which is supported so as not to rotate the filtration plate 24 and has a coupling hole 20b corresponding to the coupling piece 17a at the upper end of the supporter 17, .

주입액 주입구(10)에 주입된 주입액이 여과판 받침구(20)와 제1필터하우징(13)의 상호밀착면 틈새를 통해 누출되는 것을 방지하기 위한 제1오링(25);A first O-ring 25 for preventing the infusion liquid injected into the injection solution inlet 10 from leaking through a clearance between the filter plate support 20 and the first filter housing 13;

주입액 여과재(15)를 통과한 주입액이 여과판 받침구(20)의 결합공(20b)과 서포터(17)의 결합편(20b)사이의 틈새를 통해 누출되는 것을 방지하기 위한 제2오링(26);을 구비할 수 있다.A second O-ring (not shown) for preventing the infusion liquid that has passed through the infusion liquid filtering material 15 from leaking through a gap between the engaging hole 20b of the filter plate support 20 and the engaging piece 20b of the supporter 17 26).

제2필터하우징(19)의 외주연에 원주방향으로 등간격을 유지하여 형성되고, 제2필터하우징(19) 외주연을 파지하여 제1필터하우징(13)에 대해 제2필터하우징(19)을 결합 또는 분리시킬 경우 미끄러지는 것을 방지하기 위한 논슬립용 돌출부(29);를 구비할 수 있다.The second filter housing 19 is formed at an outer circumference at an equal interval in the circumferential direction and is held by the second filter housing 19 with respect to the first filter housing 13 by grasping the outer periphery of the second filter housing 19. [ And a non-slip protrusion 29 for preventing slippage when joining or separating the non-slip protrusion 29. [

여과판(24)의 가장자리에 걸림홈(24a)이 형성되고, 걸림홈(24a)과 대응되고, 제1필터하우징(13)의 여과공간에 형성되는 결합홈(13a)에 대응되는 걸림돌기(20a)가 여과판 받침구(20)의 상면에 대향되게 형성됨에 따라,The engaging groove 24a is formed at the edge of the filter plate 24 and corresponds to the engaging groove 13a formed in the filtration space of the first filter housing 13 and corresponds to the engaging groove 24a. Is formed to face the upper surface of the filter plate support 20,

주사기를 통해 주입액 주입공(10)을 통해 주입액을 주입액 여과재(15)에 주입시킬 경우, 결합홈(13a)에 결합되는 걸림돌기(20a)에 여과판(24)의 걸림홈(24a)이 요철결합되어 회전되지않도록 지지된다.When the injection liquid is injected into the injection liquid filter material 15 through the injection liquid injection hole 10 through the injector, the engagement grooves 24a of the filter plate 24 are inserted into the engagement protrusions 20a, So as not to rotate.

목적물질 통과공(14)은 추출되는 목적물질의 종류에 따라 천공되는 직경이 가변될 수 있다. 일 예로서 목적물질 통과공(14)의 직경이 80㎛이하일 경우에는 목적물질이 원활하게 투과할 수 없게 되고, 이와 반면에 목적물질 통과공(14)의 직경이 200㎛이상일 경우에는 덩어리(소위, 불순물을 말함)를 포함한 목적물질이 투과될 수 있어 신뢰성이 떨어질 수 있다.The diameter of the perforated hole may vary depending on the type of the target material to be extracted. For example, when the diameter of the target material passage hole 14 is 80 μm or less, the target material can not be smoothly permeated. On the other hand, when the diameter of the target material passage hole 14 is 200 μm or more, , Impurities) can be transmitted, which may result in lower reliability.

서포터(17)의 외주연에 원주방향으로 형성되고, 서포터(17) 상단의 결합편(17a)을 여과판 받침구(20)의 결합공(20b)에 결합하기 위해 제1필터하우징(13) 내부에 삽입되는 서포터(17)의 흔들림을 방지하기 위한 날개형 가이드(17b);를 더 구비할 수 있다.The first filter housing 13 is formed in the circumferential direction on the outer periphery of the supporter 17 and is provided inside the first filter housing 13 so as to engage the engaging piece 17a at the upper end of the supporter 17 with the engaging hole 20b of the filter plate receiving hole 20. [ And a wing-shaped guide 17b for preventing the wing of the supporter 17 inserted into the wing guide 17b.

즉, 여과판 받침구(20)의 결합공(20b)에 서포터(17)의 결합편(17a)을 결합시키기 위해 서포터(17)의 플랜지(17c)를 제2필터하우징(19)에 안착시킨 상태에서 제1필터하우징(13) 내부에 삽입시킬 경우, 서포터(17)의 외주연에 형성된 날개형 가이드(17b)에 의해 서포터(17) 흔들림을 방지할 수 있다.That is, the flange 17c of the supporter 17 is seated on the second filter housing 19 in order to engage the engaging piece 17a of the supporter 17 with the engaging hole 20b of the filter plate support 20 It is possible to prevent the supporter 17 from being shaken by the wing-shaped guide 17b formed on the outer periphery of the supporter 17 when the first filter housing 13 is inserted into the first filter housing 13. [

이로 인해, 서포터(17) 상단의 결합편(17a)을 여과판 받침구(20)의 결합공(20b)에 쉽게 결합시킬 수 있다.The coupling piece 17a on the upper end of the supporter 17 can be easily coupled to the coupling hole 20b of the filter plate supporting hole 20. [

이하에서, 본 명세서의 일 실시예에 의한 의료 주입장치용 주입액 여과필터의 사용예를 첨부도면에 따라 상세하게 설명한다.Hereinafter, the use of the injection liquid filtration filter for a medical infusion device according to one embodiment of the present invention will be described in detail with reference to the accompanying drawings.

도 1 내지 도 4에서와 같이, 목적물질 통과공(14)이 천공된 금속판재의 여과판(24) 및 여과판(24)을 지지하는 원통형태의 여과판 받침구(20)로 이루어진 주입액 여과재(15)를 제1필터하우징(13) 내부에 형성된 여과공간(12)에 장착시킨다.As shown in Figs. 1 to 4, an injection liquid filter material 15 (hereinafter, referred to as " injection liquid filter material ") 15 comprising a filter plate 24 of a metal plate material in which a target material passage hole 14 is perforated and a cylindrical filter plate support 20 for supporting the filter plate 24 Is installed in the filtration space 12 formed in the first filter housing 13.

이때, 여과판 받침구(20)와 제1필터하우징(13)의 상호밀착면에 장착된 제1오링(25)에 의해 주사기를 통해 주입액 여과재(15) 상에 주입되는 주입액이 여과판 받침구(20)와 제1필터하우징(13)의 상호밀착면 틈새를 씰링처리할 수 있다.At this time, the infusion liquid to be injected onto the infusion liquid filter material 15 through the syringe by the first O-ring 25 mounted on the mutual contact surface of the filter plate support 20 and the first filter housing 13, The gap between the first filter housing 20 and the first filter housing 13 can be sealed.

제2필터하우징(19)에 서포터(17)의 플랜지(도면부호 미 표기됨)를 수용시킨 상태에서, 제2필터하우징(19) 외주연을 파지하여 제2필터하우징(19)의 제2나사부(18)를 이와 대응되는 제1필터하우징(13)의 제1나사부(11)에 나사결합시켜 체결한다.The outer periphery of the second filter housing 19 is gripped by the second filter housing 19 while the flange of the supporter 17 is accommodated in the second filter housing 19, (18) to the first threaded portion (11) of the corresponding first filter housing (13).

이때, 제2필터하우징(19) 외주연에 돌출되게 형성된 논슬립용 돌출부(29)에 의해 제1필터하우징(13)에 대해 제2필터하우징(19)을 용이하게 체결할 수 있다.At this time, the second filter housing (19) can be easily fastened to the first filter housing (13) by the non-slip protrusion (29) formed to protrude from the outer periphery of the second filter housing (19).

이로 인해, 서포터(17) 상단의 결합편(17a)이 여과판 받침구(20)의 결합공(20b)에 결합되어 지지함에 따라, 여과공간(12)에서 주입액 여과재(15)가 이탈되는 것을 방지할 수 있게 된다.As a result, the engagement piece 17a at the upper end of the supporter 17 is engaged with and supported by the engagement hole 20b of the filter plate support 20 so that the injection liquid filter material 15 is detached from the filtration space 12 .

이때, 여과판 받침구(20)의 결합공(20b)과 서포터(17)의 결합편(20b)사이에 장착된 제2오링(26)에 의해 주입액 여과재(15)를 통과한 주입액이 서포터(17)의 주입액 배출공(16) 외부로 누출되는 것을 방지할 수 있다.At this time, the infusion liquid, which has passed through the infusion liquid filter material 15 by the second O-ring 26 mounted between the coupling hole 20b of the filter plate support 20 and the coupling piece 20b of the supporter 17, It is possible to prevent the liquid from leaking to the outside of the infusion liquid discharge hole 16 of the injection port 17.

전술한 바와 같이 구성된 의료 주입장치용 주입액 여과필터에 의하면, 제1필터하우징(13)의 상단에 착탈가능하게 결합되는 주사기로부터 배출되는 줄기세포를 포함하는 목적물질을 주입액 주입공(10)에 주입하게 된다.According to the infusion filtration filter for a medical infusion device configured as described above, a target material containing stem cells, which is discharged from a syringe detachably coupled to the upper end of the first filter housing 13, .

주입액 주입공(10)에 주입된 목적물질은 주입액 여과재(15)의 여과판(24)에 의해 천공된 목적물질 통과공(14)을 투과한 후 주입액 주입공(10)에 연통된 서포터(17)의 주입액 배출공(16)으로 이동하게 된다.The target material injected into the injection liquid injection hole 10 is passed through the target material through hole 14 punctured by the filter plate 24 of the injection liquid filter material 15 and then passed through the supporter 10 communicated with the injection liquid injection hole 10, (16) of the injection port (17).

즉, 주입액 주입공(10)을 통과한 주입액중 줄기세포와 같은 목적물질은 주입액 여과재(15)의 여과판(24)에 미세한 크기로 천공된 목적물질 통과공(14)을 통과하여 주입액 배출공(16)에 낙하된다. 이와 반면에 주입액 주입공(10)을 통과한 주입액중 덩어리 등의 불순물은 여과판(24)의 목적물질 통과공(14)을 통과하지 못해 걸러지게 된다.That is, a target material such as stem cells in the infusion liquid that has passed through the infusion liquid injection hole 10 passes through the target material through-hole 14 punctured to a fine size on the filter plate 24 of the infusion liquid filter material 15, And drops onto the liquid discharge hole 16. On the other hand, impurities such as lumps in the injection liquid that has passed through the injection liquid injection hole 10 can not pass through the target material passage hole 14 of the filter plate 24 and are thus filtered.

이때, 주입액 여과재(15)상에 투입되는 주입액이 주입액 여과재(15)를 이루는 여과판 받침구(20)와 제1필터하우징(13)의 상호밀착면에 장착된 제1오링(25)에 의해 여과판 받침구(20)와 제1필터하우징(13)의 상호밀착면 틈새를 통해 제1필터하우징(13) 외부로 누출되는 것을 방지할 수 있게 된다.In this case, the injection liquid injected onto the injection liquid filter material 15 is mixed with the first O-ring 25 mounted on the mutual contact surface of the filter plate support 20 and the first filter housing 13 forming the injection liquid filter material 15, The first filter housing 13 can be prevented from leaking to the outside of the first filter housing 13 through the clearance between the filter plate support 20 and the first filter housing 13. [

또한, 주입액 여과재(15)를 통과한 주입액이 여과판 받침구(20)의 결합공(20b)과 서포터(17)의 결합편(20b)사이에 장착된 제2오링(26)에 의해 서포터(17)의 주입액 배출구(16) 외부로 누출되는 것을 방지할 수 있게 된다. The infusion liquid that has passed through the infusion filtration media 15 is supplied to the supporter 17 by the second O-ring 26 mounted between the coupling hole 20b of the filter plate support 20 and the coupling piece 20b of the supporter 17. [ It is possible to prevent leakage to the outside of the injection liquid outlet 16 of the injection port 17.

한편, 주입액 여과재(15)의 여과판(24)이 스테인레스스틸재로 형성되어 내구성 및 내부식성을 확보함에 따라, 주사기에 의해 주입액을 주입액 여과재(15)에 공급할 경우에도 여과판(24)에 천공되어 주입액의 목적물질만을 투과시키는 목적물질 통과공(14)의 직경이 손상되지않고 일정하게 유지될 수 있다.On the other hand, when the injection liquid is supplied to the injection liquid filter material 15 by the syringe because the filter plate 24 of the injection liquid filter material 15 is made of stainless steel to ensure durability and corrosion resistance, The diameter of the target material passage hole 14 through which the target material of the injection liquid is permeated can be kept constant without being damaged.

전술한 바와 같이 주사기에 의해 주입액 주입공(10)에 유입된 주입액중 여과판(24)에 의해 덩어리는 여과시키고 목적물질만을 통과시킬 수 있다.As described above, the lumps can be filtered by the filter plate 24 in the injection liquid introduced into the injection liquid injection hole 10 by the injector, and only the target substance can be passed.

따라서, 여과판(24) 및 서포터(17)의 주입액 배출공(16)을 차례로 통과하여 인체에 주입되는 줄기세포의 목적물질의 농도는 일정하게 유지될 수 있다.Therefore, the concentration of the target substance of the stem cells injected into the human body through the filtration plate 24 and the infusion liquid discharge hole 16 of the supporter 17 can be kept constant.

여기에서, 전술한 본 명세서에서는 바람직한 실시예를 참조하여 설명하였지만, 해당 기술분야에서 숙련된 당업자는 하기의 청구범위에 기재된 본 명세서의 사상 및 영역으로부터 벗어나지 않는 범위 내에서 본 명세서를 다양하게 수정 및 변경할 수 있음을 이해할 수 있을 것이다.It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the disclosure as defined in the following claims. As will be understood by those skilled in the art.

10; 주입액 주입공
11; 제1나사부
12; 여과공간
13; 제1필터하우징
14; 목적물질 통과공
15; 주입액 여과재
16; 주입액 배출공
17; 서포터
18; 제2나사부
19; 제2필터하우징
20; 여과판 받침구
24; 여과판
25; 제1오링
26; 제2오링
29; 논슬립용 돌출부
10; Injection fluid injection hole
11; The first threaded portion
12; Filtration space
13; The first filter housing
14; Target material through hole
15; Injection solution filter media
16; Injection fluid discharge hole
17; supporter
18; The second threaded portion
19; The second filter housing
20; Filter plate support
24; Filtration plate
25; First O-ring
26; Second O-ring
29; The non-slip projection

Claims (5)

내부에 주입액 주입공이 관통형성되고 외주연 일측에 제1나사부가 형성되며, 주입액을 여과하기 위한 여과공간이 형성되는 제1필터하우징;
상기 여과공간에 안착되고, 주입액중 임의크기의 덩어리를 여과하며 목적물질만을 투과시키기 위한 목적물질 통과공이 형성되는 주입액 여과재;
상기 주입액 주입공과 연통되는 주입액 배출공이 내부에 관통형성되며, 상기 여과공간에 장착되는 상기 주입액 여과재를 압착시켜 이탈되는 것을 방지하기 위한 서포터;
상기 제1나사부와 대응되는 제2나사부가 내주연에 형성되고, 상기 제1,2나사부를 나사결합시킬 경우 상기 서포터의 플랜지를 지지하여 상기 제1필터하우징으로부터 상기 서포터가 이탈되는 것을 방지하기 위한 제2필터하우징;을 구비하는 의료 주입장치용 주입액 여과필터에 있어서:
상기 주입액 여과재는
상기 주입액 주입공의 출구측에 장착되고, 상기 목적물질 통과공이 천공되는 여과판; 상기 여과판이 회전되지않도록 받쳐 지지하고, 상기 서포터 상단의 결합편과 대응되는 결합공이 중앙에 관통형성되는 원통형태의 여과판 받침구;를 구비하고,
상기 여과판의 가장자리에 걸림홈이 형성되고, 상기 걸림홈과 대응되고, 상기 제1필터하우징의 여과공간에 형성되는 결합홈에 대응되는 걸림돌기가 상기 여과판 받침구의 상면에 대향되게 형성됨에 따라, 상기 주입액 주입공을 통해 주입액을 상기 주입액 여과재에 주입시킬 경우 상기 결합홈에 결합되는 상기 걸림돌기에 상기 여과판의 걸림홈이 요철결합되어 회전되지않도록 지지되는 것을 특징으로 하는 의료 주입장치용 주입액 여과필터.
A first filter housing through which an injection solution injection hole is formed, a first screw portion is formed on an outer peripheral side of the first filter housing, and a filtration space for filtering the injection solution is formed;
An injection liquid filter material which is seated in the filtration space and which forms a target material through hole for filtering a lump of an arbitrary size of the injection liquid and transmitting only a target material;
A supporter for penetrating the infusion liquid discharge hole communicating with the infusion liquid infusion hole and preventing the infusion liquid filter material mounted on the filtration space from being squeezed out;
A second threaded portion corresponding to the first threaded portion is formed on the inner circumference of the first filter housing and a flange of the supporter is screwed on the first and second threaded portions to prevent the supporter from being detached from the first filter housing And a second filter housing, the injection filter filtration filter comprising:
The infusion fluid filter medium
A filter plate mounted on an outlet side of the injection liquid injection hole, the target substance passage hole being perforated; And a cylindrical filter plate support hole which is supported so as not to rotate the filtration plate and which has an engagement hole corresponding to the engagement piece at the upper end of the supporter,
And a latching protrusion corresponding to the engaging groove formed in the filtration space of the first filter housing is formed to face the upper surface of the filter plate support, Wherein when the injection liquid is injected into the injection liquid filter material through the liquid injection hole, the engagement groove of the filter plate is concavely and reliably coupled to the engagement protrusion coupled to the engagement groove, so that the injection liquid filter is not rotated. filter.
삭제delete 제1항에 있어서,
상기 서포터의 외주연에 원주방향으로 형성되고, 상기 서포터 상단의 결합편을 상기 여과판 받침구의 결합공에 결합하기 위해 상기 제1필터하우징 내부에 삽입되는 상기 서포터의 흔들림을 방지하기 위한 날개형 가이드;를 더 구비하는 것을 특징으로 하는 의료 주입장치용 주입액 여과필터.
The method according to claim 1,
A wing-like guide formed in a circumferential direction on an outer circumference of the supporter, for preventing shaking of the supporter inserted into the first filter housing to engage a coupling piece on an upper end of the supporter with a coupling hole of the filter plate support; Further comprising: an injection port for injecting fluid into the medical injection device.
삭제delete 제1항에 있어서,
상기 제2필터하우징의 외주연에 원주방향으로 등간격을 유지하여 형성되고, 상기 제2필터하우징 외주연을 파지하여 상기 제1필터하우징에 대해 상기 제2필터하우징을 결합 또는 분리시킬 경우 미끄러지는 것을 방지하기 위한 논슬립용 돌출부;를 구비하는 것을 특징으로 하는 의료 주입장치용 주입액 여과필터.


The method according to claim 1,
Wherein the second filter housing is formed with an equal interval in the circumferential direction at an outer periphery of the second filter housing, and when the second filter housing is engaged with or separated from the first filter housing by grasping the outer periphery of the second filter housing, And a non-slip protrusion for preventing the fluid from entering the medical fluid injecting device.


KR1020170151221A 2017-10-31 2017-11-14 a filter of injection device for medical use KR101833729B1 (en)

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KR20210134457A (en) 2020-05-01 2021-11-10 박준한 Mixing Fluid Filtering Apparatus
WO2022112371A1 (en) 2020-11-25 2022-06-02 Terumo Europe N.V. Filter needle

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KR100628364B1 (en) * 2005-07-07 2006-09-27 메디칸(주) Syringe piston using in fat transplantation
EP2679273A1 (en) * 2012-06-27 2014-01-01 Industrie Borla SpA One-way valve for medical lines
KR20150005267A (en) * 2013-07-05 2015-01-14 주식회사 씨피엘 Safety filter for syringe
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KR20150081227A (en) * 2014-01-03 2015-07-13 동국대학교 산학협력단 Filter needle
KR101647738B1 (en) * 2016-07-05 2016-08-18 씨엔엠테크 주식회사 Filter module for syringe
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JPS5229790U (en) * 1975-08-23 1977-03-02
KR100628364B1 (en) * 2005-07-07 2006-09-27 메디칸(주) Syringe piston using in fat transplantation
EP2679273A1 (en) * 2012-06-27 2014-01-01 Industrie Borla SpA One-way valve for medical lines
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210134457A (en) 2020-05-01 2021-11-10 박준한 Mixing Fluid Filtering Apparatus
KR102468841B1 (en) * 2020-05-01 2022-11-22 박준한 Mixing Fluid Filtering Apparatus
WO2022112371A1 (en) 2020-11-25 2022-06-02 Terumo Europe N.V. Filter needle
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