KR101820062B1 - Magnetic Simulator - Google Patents

Magnetic Simulator Download PDF

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Publication number
KR101820062B1
KR101820062B1 KR1020160004209A KR20160004209A KR101820062B1 KR 101820062 B1 KR101820062 B1 KR 101820062B1 KR 1020160004209 A KR1020160004209 A KR 1020160004209A KR 20160004209 A KR20160004209 A KR 20160004209A KR 101820062 B1 KR101820062 B1 KR 101820062B1
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South Korea
Prior art keywords
magnetic
coil
magnetic field
body portion
stimulator
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KR1020160004209A
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Korean (ko)
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KR20170084848A (en
Inventor
김동철
김준형
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서강대학교산학협력단
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/004—Magnetotherapy specially adapted for a specific therapy

Abstract

The magnetic stimulator according to the present invention includes a body portion and a magnetic coil having a protrusion directed toward the conductor from the body portion to form a time-varying magnetic field by a current applied from the outside, and the magnetic coil includes a first magnetic coil And a pair of second magnetic coils, wherein the body portion is arranged laterally side by side so that the protrusions are in contact with each other, thereby forming a concentrated magnetic field in the protrusions.

Description

Magnetic stimulator {Magnetic Simulator}

The present invention relates to a magnetic stimulator, and more particularly, to a magnetic stimulator for stimulating the brain, which is a method for stimulating the brain without surgical operation.

Transcranial magentic stimulation (TMS) is a high magnetic field generated by flowing a fixed flow between magnetic coils for 0.2 - 0.9 msec, allowing a current to flow through the cerebral cortex and stimulating the brain without surgery . By applying a time-varing magnetic field outside the human body to induce an induced electric field induced by the Faraday's induction law inside the human body, It is a non-invasive technique that gives electrical stimulation to the tissue. This is mainly focused on depression, but studies are under way on various fields such as tinnitus, pain treatment, and post-stroke neuropsychiatric rehabilitation.

As a prior art device for such cranial brain stimulation, Patent Registration No. 0696724 entitled " Magnetic stimulator with enhanced magnetic field density ". The prior art discloses a magnetic stimulator comprising a magnetic coil forming a time-varying magnetic field by a pulse-shaped current applied from the outside, and a conductive shielding member disposed at a lower portion of the magnetic coil for blocking transmission of a magnetic field radiated by the magnetic coil Lt; / RTI > In this technique, the stimulator is placed at a position perpendicular to the cerebral hemisphere, the stimulus position is gradually shifted, a point indicating the greatest motor-induced potential is found, and the stimulus intensity is determined based on the threshold value. Of brain stimulation.

However, in the conventional TMS apparatus including the prior art, the electromagnetic field generated in the electromagnetic coil is greatly reduced as the distance from the coil is increased, and the effect is stimulated only in the cortex of the brain within about 2 to 3 cm from the scalp There is a problem that is limited to doing. In addition, since the shape of the coil used in the conventional magnetic stimulator is a donut shape or a top shape corresponding to a single coil, there is a problem that locally irritation is difficult because a focus is not formed at a desired site.

Korean Registered Patent No. 10-0696724 (registered on March 12, 2007)

SUMMARY OF THE INVENTION The present invention has been made to overcome the above-mentioned problems, and it is an object of the present invention to provide a magnetic stimulator having a higher magnetic field density than the conventional magnetic stimulator.

Another object of the present invention is to provide a magnetic stimulator which can be easily manufactured while having a high brain stimulation efficiency under the same conditions.

According to an aspect of the present invention, there is provided a magnetic sensor comprising: a body portion; and a magnetic coil having a protrusion toward the conductor in the body portion to form a time-varying magnetic field by a current applied from the outside, A magnetic stimulator may be provided which is composed of a pair of a coil and a second magnetic coil, and the body is laterally arranged so that the protrusions are in contact with each other so as to form an intensive magnetic field on the protrusions.

The protruding portion may include a lower vertical portion bent downward from one side of the body portion, a horizontal portion bent horizontally to the body portion at the lower vertical portion, and an upper vertical portion bent toward the body portion from the horizontal portion. It can have a U-shape.

In addition, the body portion may be formed in a rectangular shape so that one side edge thereof is in contact with one another.

In addition, the protrusion may be located at the center of one side edge of the rectangular body.

Further, the first magnetic coil forms a current flow in a clockwise direction, and the second magnetic coil forms a current flow in a counterclockwise direction, so that the magnetic field can be amplified.

The magnetic stimulator according to the present invention has a protrusion directed toward the conductor from the body portion of the magnetic coil, and has an advantage that it has an induced magnetic field of a size larger than that of the conventional art.

Further, by forming a concentrated magnetic field on the protruding portion of the magnetic coil, there is an advantage that it is easy to use intensively at a specific position desired by the user.

Further, since the magnetic coil has a simple shape of the body portion and the protruding portion, the manufacturing process is simplified and the manufacturing process time is reduced.

In addition, since the pair of magnetic coils are each formed of a square shape, it is possible to manufacture easily and have a wide contact area, so that a magnetic field of an improved size compared to the conventional one can be formed.

1 is a perspective view of a magnetic stimulator according to an embodiment of the present invention.
FIG. 2 illustrates one magnetic coil in the magnetic stimulator of FIG. 1; FIG.
3 shows a conventional type 1 magnetic stimulator.
Fig. 4 shows a conventional type magnetic magnetic stimulator.
5 shows a conventional type 3 magnetic stimulator.
6 shows the intensity of the maximum magnetic field generated when a current is applied to the first type magnetic magnetic stimulator.
7 shows the intensity of the maximum magnetic field generated when a current is applied to the second type magnetic magnetic stimulator.
8 shows the intensity of the maximum magnetic field generated when a current is applied to the type-3 magnetic stimulator.
FIG. 9 shows the intensity of a maximum magnetic field generated when a current is applied to a magnetic stimulator according to an embodiment of the present invention.
10 shows the intensity of the maximum electric field generated when a current is applied to the first type magnetic magnetic stimulator.
11 shows the intensity of the maximum electric field generated when a current is applied to the second type magnetic magnetic stimulator.
12 shows the intensity of the maximum electric field generated when a current is applied to the type-3 magnetic stimulator.
FIG. 13 shows the intensity of a maximum electric field generated when a current is applied to a magnetic stimulator according to an embodiment of the present invention.
14 shows the intensity of the maximum magnetic field generated when a current is applied to the first type magnetic demagnetizer.
15 shows the intensity of a maximum magnetic field generated when a current is applied to the second type magnetic magnetic stimulator.
16 shows the intensity of the maximum magnetic field generated when a current is applied to the type-3 magnetic stimulator.
17 shows the intensity of a maximum magnetic field generated when a current is applied to a magnetic stimulator according to an embodiment of the present invention.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings. The embodiments described below are provided by way of example so that those skilled in the art will be able to fully understand the spirit of the present invention. The present invention is not limited to the embodiments described below and may be embodied in other forms. In order to clearly explain the present invention, parts not related to the description are omitted from the drawings, and the width, length, thickness, etc. of the components may be exaggerated for convenience. Like reference numerals designate like elements throughout the specification.

FIG. 1 is a perspective view of a magnetic stimulator according to an embodiment of the present invention, and FIG. 2 illustrates one magnetic coil in the magnetic stimulator of FIG. 1. Here, FIG. 2 shows only the second magnetic coil 200 as an example. Referring to FIG. 1, a magnetic stimulator according to an embodiment of the present invention includes a first magnetic coil 100 and a second magnetic coil 200. Here, the illustrated conductor E refers to a place where the induction magnet generated by the magnetic stimulator is applied, and may be a head portion of a person in a light cranial stimulation, but is not limited thereto.

The first magnetic coil 100 and the second magnetic coil 200 are formed as a pair, and can form a magnetic field amplified by interference with the contact surface. The first magnetic coil 100 and the second magnetic coil 200 may have the same shape and may be disposed symmetrically with respect to a contact surface where the protrusions 120 and 220 abut. Hereinafter, the first magnetic coil 100 will be described as a reference.

The first magnetic coil 100 forms a time-varying magnetic field by a current applied from the outside. Although a method of applying a current from the outside is not shown in the drawing, it may be realized by a circuit composed of a conductor on one side of the body 110, which will be described later. At this time, the circuit may be connected to a power source and voltage conversion may be performed by a converter or the like, but is not limited thereto. The first magnetic coil 100 includes a body 110 and a protrusion 120.

The body portion 110 serves as a support and can guide a one-way current flow. The body portion 110 may include a first body portion 111, a second body portion 112, a third body portion 113, and a fourth body portion 114. At this time, each of these parts can be determined by the direction of current flow. The first body part 111 and the third body part 113 guide current flow in opposite directions and the second body part 112 and the fourth body part 114 also conduct current in opposite directions It is an expression to guide. The current flows from the first body part 111 to the first body part 111 through the second body part 112, the third body part 113 and the fourth body part 114 and flows in one direction .

The body 110 may have a rectangular shape and may have one side edge, that is, the first body 111 and the first body 211 of the second magnetic coil 200 may be in contact with each other. At this time, the first body part 111 is provided with a protruding part 120 to be described later, so that a concentrated magnetic field can be formed together with the protruding part 220 provided on the second magnetic coil 200. The first magnetic coil 100 and the second magnetic coil 200 are formed as a pair and the protrusions 120 and 220 are in contact with each other and the body portions 110 and 120 are arranged side by side on the same plane.

The protrusions 120 are formed of a U-shaped downward vertical portion 121, a horizontal portion 122, and an upper vertical portion 123 to form an intense magnetic field. At this time, the protrusion 120 may be located at a corner of one side of the square, for example, the center of the first body 111, corresponding to the rectangular body 110.

The protrusion 120 may form a magnetic field separate from the body 110. The body part 110 having one closed loop is formed by the current flow from the first body part 111 to the second body part 112, the third body part 113 and the fourth body part 114, And the protruding portion 120 forms a separate magnetic field from the flow of current flowing to the downward vertical portion 121, the horizontal portion 122 and the upward vertical portion 123. This forms a concentrated magnetic field, which leads to a remarkable increase in the effect compared to the prior art.

The protrusions 120 may be arranged so that current flows in the same direction as the protrusions 220 provided in the second magnetic coil 200. [ The magnetic coils 100 and 200 are arranged such that the magnetic field generated by the magnetic coils 100 and 200 is amplified. For example, in the first magnetic coil 100, a current flows from the fourth body part 114 to the second body part 112 via the first body part 111, Flows from the fourth body portion 214 to the second body portion 212 through the first body portion 211.

The first magnetic coil 100 has been described above. The second magnetic coil 200 may have substantially the same shape as the first magnetic coil 100 including the body 210 and the protrusion 220 and may perform the same function. At this time, the body 210 of the second magnetic coil 200 includes a first body 211, a second body 212, a third body 213, and a fourth body 214, The protrusion 220 may include a downward vertical portion 221, a horizontal portion 222, and an upright vertical portion 223. Since this has been described above with reference to the first magnetic coil 100, detailed description thereof will be omitted.

A magnetic stimulator according to one embodiment of the present invention may be used for various types of treatment, for example, depression, neuropathic treatment, or stimulation of the cerebral region. It can be used by the following sequence.

First, a magnetic stimulator according to an embodiment of the present invention may be connected to a power source (S1) together with other medical devices for the purpose of the procedure. At this stage, whether the magnetic stimulator is operated or not may be determined by operating a separate switch after the magnetic stimulator is connected to the power source. If you want to use the magnetic stimulator, switch it on. If you do not want to use it, switch it off.

Next, if a cerebral stimulation site is determined at a specific position of the head of the user according to the disease or symptom, a magnetic stimulator may be installed at the specific position (S2). At this time, the stimulation by the magnetic stimulator according to the present invention can be performed in the form of an area stimulus in which the focus of the stimulation is cyclically shifted over a certain region. Thus, the area stimulation site should be determined (S2). The determination of the site to be stimulated at this time can be performed according to a method known in the art, but is not limited thereto.

If the area stimulation site is determined (S2), then the stimulation focus can be determined (S3). The determination of the stimulus focus refers to the area in which the focus is moved, the time at which the focus moves, the intensity of the magnetic field at the focus, and the depth at which the focus is formed in the stimulus. This can be achieved by the protrusions 120 and 220 shown in FIG. 1 or FIG.

When the stimulation focus is determined in the stimulation region (S3), a time-varying magnetic field may be applied (S3). The time-varying magnetic field may be generated through voltage or current control applied to both ends of each magnetic coil unit. The focus can be changed at the area stimulation site by application of the time-varying magnetic field (S4) and movement of the magnetic stimulator.

Next, it may be determined whether the focus change is according to a preset value (S5). If it is out of the preset range of values, the time-varying magnetic field can be adjusted again (S6). On the other hand, the time-varying magnetic field can be repeatedly applied if it is within the range of the predetermined value (S4). The parameters of the preset values may be, for example, time, stimulus size or focus position, but are not limited thereto.

When a time-varying magnetic field is formed from the magnetic coils 100 and 200 by a control unit (not shown), a stimulation focal point may be formed on a stimulus signal corresponding to a certain region of the cerebrum. Only one focus can be formed at a specific time and can be moved in the stimulus region according to the change of time. The depth of focus can be controlled by the intensity of the magnetic field and the degree of stimulation can be determined by a microcurrent measuring device (not shown). At this time, the stimulation in the stimulation region can be repeatedly performed.

The magnetic stimulator according to an embodiment of the present invention used in this manner is provided with projections 120 and 220 directed toward the conductor E from the body portions 110 and 210 of the magnetic coils 100 and 200 to improve the induced magnetic field density And the concentrated magnetic field is formed on the protrusions 120 and 220 of the magnetic coils 100 and 200, which is advantageous in that it is easy to use intensively at a specific position desired by the user.

In addition, since the body portions 110 and 210 and the protrusions 120 and 220 of the magnetic coils 100 and 200 are formed in a simple shape, the manufacturing process is simplified and the manufacturing process time is shortened. In the case where the pair of magnetic coils 100 and 200 are rectangular So that a magnetic field having an improved size compared to the conventional magnetic field can be formed. These effects can be proved by the measurement data. Hereinafter, the measurement data will be described after the comparison target group is described first.

FIG. 3 shows a conventional type 1 magnetic magnetic stimulator, FIG. 4 shows a conventional type 2 magnetic stimulator, and FIG. 5 shows a conventional type 3 magnetic stimulator.

The first-type magnetic stimulator 10 generates a magnetic field in such a manner that the first-type first magnetic coil 11 and the first-type second magnetic coil 12 are in contact with each other on the same plane as shown. This type 1 magnetic stimulator 10 is generally used, and it arranges two circular coils having a relatively large diameter of about 60 to 100 mm in a palm shape. Magnetic coils of this shape stimulate a wide range of cortical areas, usually corresponding to a circle area of 40 to 70 mm in diameter or more, and as a result, it is very inaccurate to selectively stimulate only the nerve tissue of a specific local region A problem arises.

The second type magnetic magnetic stimulator 20 is composed of three magnetic coils and includes a first magnetic coil 21, a second magnetic coil 22 and a third magnetic coil 23. This is to solve the problem of the first type magnetic magnetic stimulator 10, and is a method using three or more circular coils, which is also called a Slinky Coil method. The illustrated magnetic coil combinations have structures that additionally add a circular coil in the first type magnetic stimulator 10. Here, the third magnetic coil 23 added additionally serves to partially reinforce or cancel the spatial magnetic field generated by the first magnetic coil 21 and the second magnetic coil 22.

However, the intensity of the induced electric field induced in the brain is slightly increased compared to the conventional type 1 magnetic stimulator 10, but the field localization of the magnetic field is reduced. There is a problem that the requirement of the user can not be satisfied.

The third type magnetic stimulator 30 is composed of four magnetic coils and includes a magnetic coil 31, a magnetic coil 32, a magnetic coil 33 and a magnetic coil 34. This is characterized in that the four magnetic coils have a shape that abuts on the same plane, but this configuration also does not solve the problems of the first type magnetic stimulator 10 and the second type magnetic stimulator 20. [ Hereinafter, measurement data obtained by performing the above-mentioned first, second, and third magnetic stimulators 10, 20, and 30 on the comparison target group will be described.

<Proof for Increasing Inductive Field Accumulation>

FIG. 6 shows the intensity of the maximum magnetic field generated when a current is applied to the first type magnetic magnetic stimulator, FIG. 7 shows the intensity of the maximum magnetic field generated when current is applied to the second type magnetic magnetic stimulator, 3 shows the intensity of the maximum magnetic field generated when a current is applied to the magnetic stimulator.

Referring to the drawings, a magnetic stimulator according to an embodiment of the present invention, unlike the first type magnetic stimulator (10, butterfly coil) and other types of magnetic stimulators using a circular coil, has a square type coil ), Where the maximum induced magnetic field is increased when the same current is applied to the square coil as follows. This is because the contact area between the two coils is widened because the contact area between the two coils is widened and the magnetic field generated by the current flowing through the coil is further overlapped.

Further, the protrusions 120 and 220 according to the present invention are oriented in a direction close to the conductor E, which uses a principle that the intensity of the magnetic field induced as the distance between the conductor E and the coil approaches becomes large. In the present invention, the maximum intensity of the induced magnetic field is increased by about 2.4 times as compared with that of the butterfly coil 10, and the distribution area is also significantly narrowed.

In addition, the superiority of the proposed shape can be quantitatively confirmed by comparison analysis with the second and third type magnetic stimulators 20 and 30 (slinky coil, 4-leaves coil). Moreover, since the present invention has a relatively simple shape as compared with other shapes, the present invention has an advantage that it is easy to produce. The table below compares them.

Type 1
(butterfly coil) Type 2
(slinky coil) Type 3
(4-leaves coil) Patents The intensity of the maximum magnetic field (× 10 6 A / m 2 ) 3.39 4.05 3.68 8.19

&Lt; Proof of high density of electric field induced by magnetic field >

Fig. 10 shows the intensity of the maximum electric field generated when a current is applied to the first type magnetic magnetic stimulator, Fig. 11 shows the intensity of the maximum electric field generated when current is applied to the second type magnetic magnetic stimulator, FIG. 13 shows the intensity of a maximum electric field generated when a current is applied to a magnetic stimulator according to an embodiment of the present invention, and FIG. 13 shows an intensity of a maximum electric field generated when a current is applied to the magnetic stimulator according to an embodiment of the present invention.

Referring to this, not only the magnetic field characteristics of the ultra-high density as described above, but also the electric field characteristics of a further high integration degree are described as follows. The electric field induced by the magnetic field of each coil is shown, which shows that the intensity of the maximum electric field of the induced electric field of the proposed shape is overwhelmingly large.

Type 1
(butterfly coil) Type 2
(slinky coil) Type 3
(4-leaves coil) Patents The intensity of the maximum electric field (× 10 3 V / m) 1.158 0.363 4.237 195.0

<Proof of high efficiency of induced magnetic field>

In order to evaluate the effectiveness of the proposed shape, the lower ends of the coil shape were all matched and the intensity of the induced magnetic field was compared. This is different from the above-described < Proof for Increasing the Inductive Field Accumulation > and the measurement method are the same, but the magnetic coils of the first to third types are disposed closer to the conductor E.

That is, by positioning the magnetic coils of the first to third types in the same plane as the protrusions 120 and 220 of the present invention, it was confirmed which coils can obtain a higher magnetic field with the same current in actual use.

The results of the analysis below show the induced magnetic field in the conductor E when the first to third magnetic coils are placed on the same plane as the protrusions 120 and 220 of the proposed shape, The maximum induced magnetic field is lower than the intensity of the induced magnetic field in the proposed patent. Therefore, it can be seen that the amount of current to be applied to the coil in order to obtain the intensity of the same local magnetic field is the smallest in the proposed patent. That is, the proposed shape has the highest efficiency.

Type 1
(butterfly coil) Type 2
(slinky coil) Type 3
(4-leaves coil) Patents The intensity of the maximum electric field (× 10 6 A / m 2 ) 6.50 7.42 6.04 8.19

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is clearly understood that the same is by way of illustration and example only and is not to be taken by way of limitation, You will understand. Accordingly, the true scope of the invention should be determined only by the appended claims.

E: conductor 10: type 1 magnetic stimulator
11: first type first magnetic coil 12: first type magnetic coil
20: type 2 magnetic stimulator 21: type 2 magnetic coil
22: second type second magnetic coil 23: second type third magnetic coil
30: Type 3 magnetic stimulator 31: Type 3 magnetic coil
32: third type magnetic coil 33: third type magnetic coil
34: a third type magnetic coil 100: a first magnetic coil
110: body part 111: first body part
112: second body part 113: third body part
114: fourth body part 120: protrusion
121: downward vertical portion 122: horizontal portion
123: upper vertical part 200: second magnetic coil
210: body part 211: first body part
212: second body portion 213: third body portion
214: fourth body part 220: protrusion
221: downward vertical part 222: horizontal part
223: Upper vertical part

Claims (5)

And a magnetic coil having a body portion and a protrusion facing the conductor in the body portion to form a time-varying magnetic field by a current applied from the outside,
The magnetic coil
Wherein the body portion is arranged side by side so that the protrusions are in contact with each other so as to form an intense magnetic field in the protrusions,
The protrusion includes a lower vertical portion bent downward from one side of the body portion, a horizontal portion bent horizontally to the body portion at the lower vertical portion, and an upper vertical portion bent toward the body portion from the horizontal portion, A magnetic stimulator provided in a shape. delete And a magnetic coil having a body portion and a protrusion facing the conductor in the body portion to form a time-varying magnetic field by a current applied from the outside,
The magnetic coil
Wherein the body portion is arranged side by side so that the protrusions are in contact with each other so as to form an intense magnetic field in the protrusions,
The body portion
The magnetic stimulator has a rectangular shape and is disposed so that one side edge is in contact with the other. The method of claim 3,
The protrusion
And is located at the center of one side edge of the rectangular body. 5. The method according to any one of claims 1 to 4,
The first magnetic coil forms a current flow in a clockwise direction,
And the second magnetic coil forms a current flow in a counterclockwise direction so that the magnetic field is amplified.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001276234A (en) * 2000-01-27 2001-10-09 Nippon Koden Corp Coil device for treating urinary incontinence
JP2012125546A (en) * 2010-11-25 2012-07-05 Osaka Univ Magnetic coil, and transcranial magnetic stimulation system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001276234A (en) * 2000-01-27 2001-10-09 Nippon Koden Corp Coil device for treating urinary incontinence
JP2012125546A (en) * 2010-11-25 2012-07-05 Osaka Univ Magnetic coil, and transcranial magnetic stimulation system

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