KR101785831B1 - Biological Signal Detecting System - Google Patents

Biological Signal Detecting System Download PDF

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KR101785831B1
KR101785831B1 KR1020160021121A KR20160021121A KR101785831B1 KR 101785831 B1 KR101785831 B1 KR 101785831B1 KR 1020160021121 A KR1020160021121 A KR 1020160021121A KR 20160021121 A KR20160021121 A KR 20160021121A KR 101785831 B1 KR101785831 B1 KR 101785831B1
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light
light emitting
sensor module
quantum dot
comparison result
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KR20170099129A (en
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노용영
류기성
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동국대학교 산학협력단
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4806Sleep evaluation
    • A61B5/4809Sleep detection, i.e. determining whether a subject is asleep or not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4884Other medical applications inducing physiological or psychological stress, e.g. applications for stress testing
    • G06F19/3418
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06QINFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q50/00Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
    • G06Q50/10Services
    • G06Q50/22Social work or social welfare, e.g. community support activities or counselling services
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
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Abstract

The present invention includes a light emitting module that irradiates light of a predetermined wavelength into a human body using a Quantum dot sheet, and a sensor module that receives light transmitted through and reflected from the inside of the human body by the light emitting module .

Description

{Biological Signal Detecting System}

The present invention relates to a bio-signal meter reading system, and more particularly, to a bio-signal meter reading system that irradiates light of a specific wavelength generated in a Quantum dot sheet into a human body, receives light transmitted and reflected inside the human body, To a biological signal meter reading system.

Recently, the "smart health care industry" using human bio signal has emerged as the center of gravity shifts from medical treatment paradigm to prevention and management for the development of BT and IT convergence technology and further reduction of medical expenses in the age of aging. However, for the prevention and management of the disease, blood sampling, medication, CT, and MRI are necessary. As such, the examination of the hospital is costly and time-consuming, and has disadvantages that occur intermittently. Therefore, there is a growing demand for healthcare in daily life that can overcome these problems.

In addition, bio-signal information obtained for healthcare can be analyzed and standardized and information of human senses can be utilized to provide emotional customized products and emotional services according to the situation. For this purpose, technical requirements for accurate bio-signal acquisition are increasing. Therefore, the bio-signal collecting device should be developed more accurately and portable.

Korean Registered Patent No. 10-1237308 (Registered on February 20, 2013)

SUMMARY OF THE INVENTION Accordingly, it is an object of the present invention to provide a biological signal meter reading system capable of irradiating light into a human body to non-invasively identify a biological signal.

Another object of the present invention is to provide a biological signal meter reading system capable of irradiating light of various wavelengths into a human body in one light emitting module.

It is another object of the present invention to provide a bio-signal meter reading system capable of receiving biometric signal data and comparing the received data with predetermined reference values and storing the comparison result.

It is another object of the present invention to provide a biological signal meter reading system capable of receiving and displaying stored comparison results.

It also analyzes the stored comparison results and provides personalized services corresponding to the analyzed bio-signals.

According to an aspect of the present invention, there is provided a light emitting module including: a light emitting module that irradiates light of a preset wavelength into a human body using a Quantum dot sheet; and a light emitting module that irradiates the inside of the human body, And a sensor module for receiving the reflected light.

Further, the light emitting module of the present invention may include a light emitting element that emits light, and a quantum dot sheet that is stacked on one side of the light emitting element and generates light of a preset wavelength when the light generated from the light emitting element is irradiated have.

The quantum dot sheet of the present invention may also include quantum dots of different sizes.

In addition, the predetermined wavelength of the present invention may correspond to at least one of wavelengths of 440 to 480 nm, 630 to 670 nm, and 920 to 960 nm.

In addition, the sensor module of the present invention can receive light using an organic photodiode.

In addition, the bio-signal meter reading system of the present invention transmits data related to light received from the sensor module, compares the received data with preset reference values, stores the comparison result, analyzes the comparison result, And may further include a server for providing a personalized service.

Further, the bio-signal meter reading system of the present invention requests transmission of the comparison result stored in the server, and when the server analyzes the comparison result and the comparison result and transmits the personalized service, And outputting the personalized service to the external device.

In addition, the bio-signal meter reading system of the present invention can measure pulse, drowsiness, and stress level using data related to light received from the sensor module.

Further, in the bio-signal meter reading system of the present invention, the sensor module may be constituted by one sensor to measure pulse, drowsiness, stress level, or the sensor module may be composed of two sensors to measure the blood pressure.

According to the biological signal meter reading system according to the present invention, there is an effect of irradiating light inside the human body and confirming the biological signal non-invasively.

According to the biological signal meter reading system according to the present invention, one light emitting module has an effect of irradiating light of various wavelengths into the human body.

According to the biological signal meter reading system according to the present invention, there is an effect that the biological signal data is received, and the received data is compared with a predetermined reference to store the comparison result.

According to the biological signal meter reading system according to the present invention, the stored comparison result is transmitted and displayed.

In addition, it has the effect of analyzing the stored comparison result and providing a personalized service corresponding to the analyzed bio-signal.

1 is a block diagram of a biological signal meter reading system according to an embodiment of the present invention.
2 is a view for explaining the operation of the light emitting module and the sensor module of the bio-signal meter reading system according to the embodiment of the present invention.
FIG. 3 is a view illustrating a light emitting module and a sensor module mounted on a substrate of the bio-signal meter reading system according to an embodiment of the present invention.
4 is a view showing the internal structure of a substrate on which a light emitting module and a sensor module of a bio-signal meter reading system according to an embodiment of the present invention are mounted.
5 is a spectrum graph showing the characteristics of the quantum dot.
6 is a graph showing the relationship between the size of quantum dot and the wavelength of emitted light.
FIG. 7 is a graph showing absorption spectra of visible light and IR (infrared ray) regions according to presence or absence of adsorption of hemoglobin on corals.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, the present invention will be described in detail with reference to the accompanying drawings. First, it should be noted that, in the drawings, the same components or parts have the same reference numerals as much as possible. In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted so as to avoid obscuring the subject matter of the present invention.

The terms "about "," substantially ", etc. used to the extent that they are used herein are intended to be taken to mean an approximation of, or approximation to, the numerical values of manufacturing and material tolerances inherent in the meanings mentioned, Accurate or absolute numbers are used to help prevent unauthorized exploitation by unauthorized intruders of the referenced disclosure.

In the embodiment of the present invention, 'communication', 'communication network' and 'network' can be used in the same sense. The three terms refer to wired and wireless local area and wide area data transmission and reception networks capable of transmitting and receiving a file between a user terminal, a terminal of another user, and a download server.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 is a block diagram of a biological signal meter reading system according to an embodiment of the present invention.

Referring to FIG. 1, a biological signal meter reading system according to an embodiment of the present invention includes a light emitting module 100, a sensor module 200, a server 300, and a terminal 400.

The light emitting module 100 performs a function of irradiating light of a predetermined wavelength predetermined outside the human body into the human body using the Quantum DotSheet.

The sensor module 200 irradiates the inside of the human body in the light emitting module 100, and receives the light transmitted and reflected inside the human body.

Since the light received by the sensor module 200 is transmitted through the tissue formed inside the human body or reflected by the tissue, the intensity and the absorbance of the light emitted from the light emitting module 100 are changed as compared with the light irradiated into the human body.

The sensor module 200 receives light using an organic photodiode. Here, the organic photodiode is a photodiode based on an organic material. These organic material-based photodiodes have good absorption spectra from UV (ultraviolet ray) to near IR (infrared ray), and almost all substrate processing acceptance through relatively low temperature processing capability And are suitable for use in BT (Bio Technology) fusion products.

The oxygen saturation in the blood can be easily determined by the blood gas analysis, which is an invasive method. However, since the non-humidified pulse oximeter according to one embodiment of the present invention can be easily and continuously measured, the oxygen saturation .

As used herein, the term " module or module " refers to a logical building block, and is not necessarily a physically distinct component, as is apparent to those skilled in the art.

The server 300 transmits data related to the light received by the sensor module 200 through the communication module 510, which will be described later, and compares the received data with a predetermined reference to store the comparison result.

The photoplethysmogram (PPG) signal corresponding to the light-related data received by the server 300 includes not only oxygen saturation but also heartbeat-related data. In more detail, pulse, drowsiness, and stress can be measured when the sensor module 200 for measuring PPG is constituted by one, and when there are two sensor modules 200, It is possible to measure blood pressure.

Therefore, the server 300 compares the heartbeat-related data with the stored heartbeat data to grasp the degree of the stress, and mitigates the degree of stress of the terminal user to the terminal 400 described later according to the detected degree of stress. It is also possible to provide a personalized service such as transferring music for personal use.

The term " server " as used herein refers to a logical unit, and it is obvious to those skilled in the art that the present invention is not necessarily physically separated.

The terminal 400 requests transmission of the comparison result stored in the server 300 and displays the transmitted comparison result when the server 300 transmits the comparison result in response to the transmission request of the comparison result .

The terminal 400 according to an embodiment of the present invention can output music transmitted from the server 300 to the personalized service in order to mitigate the degree of stress of the terminal user.

The terminal 400 means a well-known means equipped with a display module such as a well-known display module for transmitting and receiving data through a network. The terminal 400 in the present invention can install and execute an application program, But the present invention is not limited thereto. Any means capable of transmitting and receiving data through a network may be a terminal 400 of the present invention.

FIG. 2 is a view for explaining the operation of the light emitting module and the sensor module of the bio-signal meter reading system according to the embodiment of the present invention. FIG. 4 is a view illustrating an internal configuration of a substrate on which a light emitting module and a sensor module of a bio-signal meter reading system according to an embodiment of the present invention are mounted, and FIG. 5 is a cross- FIG. 6 is a graph showing the relationship between the size of quantum dot and the wavelength of emitted light. FIG. 7 is a graph showing the absorption spectrum of visible light and infrared ray (IR) region according to presence or absence of adsorption of hemoglobin Fig.

Referring to FIG. 2, when the light emitting module 100 irradiates light into the human body, it can be seen that the sensor module 200 receives the light transmitted and reflected by the internal tissue of the human body.

The light emitting module 100 and the sensor module 200 of the biological signal meter reading system according to an embodiment of the present invention may be mounted on the same plane of the substrate 500 as shown in FIG.

2 and 3, the light emitting module 100 and the sensor module 200 of the biological signal meter reading system according to the embodiment of the present invention are disposed on the same plane.

Referring to FIGS. 3 and 4, the light emitting module 100 includes a quantum dot sheet 110 and a light emitting device 120.

The quantum dot sheet 110 includes a quantum dot and the quantum dot included in the quantum dot sheet 110 may be included in the entire quantum dot sheet 110 by dividing it according to the size of the quantum dot, May be uniformly included in the whole of the quantum dot 110 irrespective of the size of the quantum dot.

3, the quantum dot sheet 110 is uniformly stacked on one side of the light emitting device 120 to be described later, and the light generated from the light emitting device 120 is irradiated to the quantum dot sheet 110 The quantum dot sheet 110 emits light of a predetermined wavelength.

 Quantum dot sheet 110 includes quantum dots of different sizes and quantum dot (quantum dot sub-quantum dot) included in quantum dot sheet 110 has a diameter of 2 to 10 nanometers (nm, 1 meter). ≪ / RTI > Quantum dot has the characteristic of emitting self-luminescence when voltage is applied like organic light-emitting diode (OLED), or absorbing and releasing light having the same wavelength.

Referring to FIG. 5, it can be seen that the wavelength generated by the quantum dot is narrower than that of the normal light.

Quantum dot is characterized by the color of light generated by the size of the quantum dot. In general, Quantum Dot generates blue light at short wavelengths with small particle size, and red light at long wavelengths with larger particle size.

Thus, the quantum dot sheet 110, which includes quantum dots of different sizes, can generate light having multiple wavelengths.

At this time, the wavelength of light generated by the quantum dot sheet 110 is at least one of wavelengths of 440 to 480 nm, 630 to 670 nm, and 920 to 960 nm.

The quantum dot sheet 110 includes quantum dots of different sizes, and in general, the quantum dots have a diameter of about 2 nm or less and blue (wavelength of 500 nm or less), a diameter of about 3 to 4 nm 550 nm), and light of a wavelength of about 6 nm to about 650 nm is generated.

In addition, Quantum dot with a size of 3 nm to 7 nm using lead sulfide (PbS) can generate light having a wavelength of 800 nm or more.

7 is a diagram showing absorption spectra of visible light and IR (infrared ray) regions according to presence or absence of adsorption of hemoglobin on corals.

One of the most important reasons for measuring photoplethysmogram (PPG) is to measure oxygen saturation in blood.

The wavelength of light for biomedical signal inspection must meet the following conditions.

First, the oxygen saturation should be a wavelength of light with a large absorption coefficient because it utilizes the absorption difference depending on the presence or absence of oxygen bonds.

Secondly, in order to calculate the oxygen saturation, a relative comparison of the measured values is required, so that the PPG value (the reference value and the relative change value) respectively measured in at least two lights is required. At this time, if the reference value and the change value vary according to the oxygen saturation, a more reliable oxygen saturation value can be extracted.

Finally, it must be light of a wavelength that can be easily implemented by devices.

Since the light of wavelengths of 440 to 480 nm, 630 to 670 nm, and 920 to 960 nm varies greatly depending on presence or absence of oxygen bonds, is relatively easy to compare, and can be easily implemented by devices, It can be used as light of a predetermined wavelength according to the example.

Referring to FIG. 7, the X axis of the graph represents the wavelength, and the Y axis represents the degree of absorption of light as an absorption coefficient. The graph is a graph plotting the absorbance for each wavelength by irradiating light to both hemoglobin and hemoglobin containing oxygen.

As shown in the graph, there are isosbestic points having the same absorption characteristic irrespective of the presence or absence of oxygen bond, but they may be significantly different from those of 660 nm wavelength. In other words, it can be seen that the measurement of oxygen saturation in the blood can be performed by using light because there is a difference in absorption characteristics with respect to light depending on the presence or absence of hemoglobin and oxygen.

It can also be seen from the graph that the wavelengths of 440 to 480 nm, 630 to 670 nm and 920 to 960 nm are more effective in comparing the differences.

Accordingly, the Quantum Dot Sheet 100 generates light having a wavelength of at least one of 440 to 480 nm, 630 to 670 nm, and 920 to 960 nm, and thereby generates a biomedical signal of oxygen saturation, heart rate, and blood pressure corresponding to one embodiment of the present invention At least one can be inspected.

The light emitting device 120 may be an organic light emitting diode (OLED), but not limited thereto, and any device that can be a light source including an organic photodiode can be used as a light emitting device.

The quantum dot sheet 110, the light emitting device 120, and the sensor module 200 can be formed of a flexible material.

The substrate 500 includes a communication module 510, a control module 520, a processing module 530, and a power module 540.

The substrate 500 may be made of at least one of PET, PC, PI, PES, PDMS, urethane, and silicon as a flexible material.

The communication module 510 receives data related to the light received by the sensor module 200 and transmits the received data to the server 300.

The communication module 510 is preferably a wireless communication module, but it is also possible to transmit data as a wired communication module.

The control module 520 controls the overall operation of the substrate 500 including the light emitting module 100 and the sensor module 200. For example, light emitted from the light emitting module 100, data associated with light at the sensor module 200, and data related to light received at the sensor module 200 at the processing module 530 are communicated To be transmitted from the module 510 to the processing module 530, and so on.

The processing module 530 includes a filter for receiving data related to the light received by the sensor module 200 from the communication module 510 to extract a living body signal and amplifying and filtering the extracted living body signal.

It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the inventions. It will be clear to those who have knowledge of.

100 ... light emitting module 200 ... sensor module
300 ... server 400 ... terminal
500 ... substrate

Claims (9)

A light emitting module that irradiates light of a predetermined wavelength into the human body using a quantum dot sheet; And
And a sensor module for receiving light transmitted through or reflected from the inside of the human body irradiated to the inside of the human body by the light emitting module,
The light emitting module includes a light emitting element for emitting light; And a quantum dot sheet laminated on one side of the light emitting device and generating light of a predetermined wavelength when the light generated from the light emitting device is irradiated, wherein the preset wavelength is 440 to 480 nm, 630 to 670 nm, and 920 to 960 nm At least one of the wavelengths,
Further comprising a server for receiving data related to the light received by the sensor module, for comparing the received data with a predetermined reference to store the comparison result, analyzing the comparison result, and providing a personalized service according to the analysis result Vital Signaling System.
delete The method according to claim 1,
Wherein the quantum dot sheet includes quantum dots of different sizes.
delete The method according to claim 1,
Wherein the sensor module receives light using an organic photodiode.
delete The method according to claim 1,
The biological signal meter reading system
Requesting transmission of the comparison result stored in the server and transmitting the comparison result and the personalized service transmitted when the server analyzes the comparison result and the comparison result and provides the personalized service to the outside And further comprising a terminal.
The method according to claim 1,
The biological signal meter reading system
And measuring at least one of a pulse rate, a degree of drowsiness, and a degree of stress using data related to light received from the sensor module.
The method according to claim 1,
The biological signal meter reading system
A sensor module for measuring a photoplethysmogram (PPG) signal corresponding to the light-related data received by the server, and a sensor module for measuring a pulse rate, a drowsiness, and a stress level And the blood pressure is measured by the difference between pulse signals when there are two sensor modules.
KR1020160021121A 2016-02-23 2016-02-23 Biological Signal Detecting System KR101785831B1 (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009302252A (en) * 2008-06-12 2009-12-24 Nissan Motor Co Ltd Organic thin film light receiving element, organic thin film light receiving/emitting element, organic thin film light receiving/emitting element array, pulse sensor using thereof and vehicle equipped with pulse sensor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009302252A (en) * 2008-06-12 2009-12-24 Nissan Motor Co Ltd Organic thin film light receiving element, organic thin film light receiving/emitting element, organic thin film light receiving/emitting element array, pulse sensor using thereof and vehicle equipped with pulse sensor

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