KR101773681B1 - Skin external preparation composition - Google Patents

Abstract

The present application relates to a skin external composition composition, a cosmetic composition or a mascara composition. The present application can provide a composition for external application for skin, a cosmetic composition or a mascara composition to which a functional polymer having low solubility for polar and non-polar solvents and having a low bleeding characteristic for the solvent is applied. The composition to which the polymer is applied may exhibit resistance to various solvents such as sebum, perspiration and tears, so that the sustainability of make-up and the like can be effectively maintained.

Description

[0001] SKIN EXTERNAL PREPARATION COMPOSITION [0002]

The present application relates to a skin external composition composition, a cosmetic composition or a mascara composition.

There are various demands for a polymer which is resistant to oily and aqueous solvents and is suitable for forming a film. For example, cosmetics such as mascara or other cosmetics or medicines applied to the skin may be required to have a film-forming polymer resistant to solvents having different properties, such as sweat, tears and sebum. Patent Documents 1 and 2 disclose polymers to be applied to the production of cosmetics.

Patent Document 1: Japanese Patent Application Laid-Open No. 2000-119140 Patent Document 2: JP-A 2003-055136

The present application provides a skin external composition composition, a cosmetic composition or a mascara composition. The present application is directed to providing a skin external composition composition, a cosmetic composition or a mascara composition comprising a functional polymer which exhibits a low solubility in polar and nonpolar solvents and is suitable for film formation in which bleeding against the solvent can be prevented, The purpose.

The composition for external application for skin of the present application may contain a polymer described later. The composition for external application for skin may be formulated into a cosmetic composition such as, for example, a mascara composition. In such a case, the composition may be formulated containing a cosmetically or dermatologically acceptable medium or base.

The formulation of the external skin application composition, cosmetic composition or mascara composition of the present application is not particularly limited and may be formed into various formulations depending on the purpose. For example, the formulation may be appropriately selected from a powder, a gel, an ointment, a cream, or a liquid. For example, the composition for external application for skin may be used as a softening agent, a nutritional lotion, a nutritional cream, a massage cream, an essence, a foam, a pack, a milky lotion, a foundation, a makeup base, a gel, a lotion, Sunflower oil, spray liquid, ointment, patch, spray, and the like.

In one example, the composition for external application for skin may be applied to a skin area where both water resistance and oil resistance are required, such as a hair growth area where sebum and sweat occur at the same time, for example, eyebrows, hair or armpits. But is not limited thereto.

For example, the mascara composition may include a polymer as described below as a film-forming agent. In this case, the mascara composition is prevented from being spread by the polymer due to tears or sweat, and smear of makeup by sebum can be prevented.

Hereinafter, the polymer contained in the composition for external application for skin, the cosmetic composition or the mascara composition will be described.

The polymer of the present application includes a polymerized unit of a hydrophilic monomer, a polymerized unit of a hydrophobic monomer, and a polymerized unit of a compound containing a silicon atom.

It is possible to form a polymer suitable for the formation of a film capable of suppressing bleeding under various conditions, while suitably including such monomers as mentioned above, exhibiting low solubility in polar and non-polar solvents.

In the present application, a polymerization unit of a monomer or a compound means a form in which the monomer or compound is polymerized and contained in the polymer as a monomer unit.

For example, the polymer may include, as the hydrophobic monomer, a first monomer having a solubility parameter of the single polymer of less than 10.0 (cal / cm ³ ) ^1/2 .

In this application, the solubility parameter refers to the solubility parameter of a homopolymer prepared by polymerizing the monomer, whereby the degree of hydrophilicity and hydrophobicity of the monomer can be determined. The manner of obtaining the solubility parameter is not particularly limited and may be in accordance with a method known in the art. For example, the parameter may be calculated or obtained according to a method known in the art as a so-called Hansen solubility parameter (HSP). The solubility parameter of a single polymer of the first monomer in the above is 5 In another example (cal / cm ^{3) 1/2} to 9.5 (cal / cm ^{3) 1/2} or 7 (cal / cm ^{3) 1/2} to 9 (cal / cm < ³ >) ^1/2 .

As the first monomer, various types of monomers can be selected and used as long as they have the above-described solubility parameters. As the monomer which can be used as the first monomer, alkyl (meth) acrylate or aromatic (meth) acrylate can be exemplified.

Examples of the alkyl group in the alkyl (meth) acrylate include linear, branched or cyclic alkyl groups of 1 to 20 carbon atoms, 4 to 20 carbon atoms, 8 to 20 carbon atoms, or 10 to 20 carbon atoms, The alkyl group may optionally be substituted by one or more substituents. The term (meth) acrylate in the present application may mean acrylate or methacrylate. Examples of the monomer include methyl (meth) acrylate, ethyl (meth) acrylate, n-propyl (meth) acrylate, isopropyl (meth) acrylate, (Meth) acrylate, n-butyl (meth) acrylate, sec-butyl (meth) acrylate, pentyl (Meth) acrylate, isooctyl (meth) acrylate, isononyl (meth) acrylate or lauryl (meth) acrylate.

As the aromatic (meth) acrylate, aryl (meth) acrylate or arylalkyl (meth) acrylate can be exemplified. The aryl group of the aryl or arylalkyl in the above may be, for example, an aryl group having 6 to 24 carbon atoms, 6 to 18 carbon atoms, or 6 to 12 carbon atoms. The alkyl group of the arylalkyl may be, for example, an alkyl group having 1 to 20 carbon atoms, 1 to 16 carbon atoms, 1 to 12 carbon atoms, 1 to 8 carbon atoms, or 1 to 4 carbon atoms. The alkyl group may be linear, branched or cyclic, and the alkyl or aryl group may be optionally substituted by one or more substituents.

Examples of the aryl group or arylalkyl group include, but are not limited to, a phenyl group, a phenylethyl group, a phenylpropyl group or a naphthyl group.

As the first monomer, for example, a compound represented by the following formula (1) can be used.

[Chemical Formula 1]

In Formula (1), Q is hydrogen or an alkyl group, B is a linear or branched alkyl or alicyclic hydrocarbon group having 5 or more carbon atoms, or an aromatic substituent such as an aryl group or an arylalkyl group.

As the alkyl group present in Q in formula (1), an alkyl group having 1 to 20 carbon atoms, 1 to 16 carbon atoms, 1 to 12 carbon atoms, 1 to 8 carbon atoms or 1 to 4 carbon atoms may be used. The alkyl group may be linear, branched or cyclic. In addition, the alkyl group may be optionally substituted with one or more substituents.

In formula (1), B may be a linear or branched alkyl group having 5 or more carbon atoms, 7 or more carbon atoms, or 9 carbon atoms, which may be optionally substituted or unsubstituted. Such a compound containing a relatively long alkyl group is known as a hydrophobic compound. The upper limit of the number of carbon atoms of the linear or branched alkyl group is not particularly limited. For example, the alkyl group may be an alkyl group having 20 or less carbon atoms.

In another embodiment, B may be an alicyclic hydrocarbon group, for example, an alicyclic hydrocarbon group having 3 to 20 carbon atoms, 3 to 16 carbon atoms, or 6 to 12 carbon atoms, and examples of such hydrocarbon groups include cyclohexyl group or iso And an alicyclic alkyl group having 3 to 20 carbon atoms, 3 to 16 carbon atoms, or 6 to 12 carbon atoms, such as boronyl group, and the like. Compounds having an alicyclic hydrocarbon group are also known as relatively hydrophobic compounds.

Substituents which may be optionally substituted in the alkyl group, the alkylene group, the aromatic substituent, the aryl group or the hydrocarbon group in the formula 1 or the other formulas described later in the present application include halogen, An epoxy group such as an epoxy alkyl group, a glycidoxyalkyl group or an alicyclic epoxy group, an acryloyl group, a methacryloyl group, an isocyanate group, a thiol group, an alkyl group, an alkenyl group, an alkynyl group or an aryl group. It is not.

In the present application, an appropriate type may be selected and used in consideration of the physical properties of the desired polymer among the monomers described above.

The polymer of the present application may also comprise polymerized units of a second monomer having a solubility parameter of 10.0 (cal / cm < ³ >) ^1/2 or more as the hydrophilic monomer. The solubility parameter of the second monomer in another example 10 (cal / cm ^{3) 1/2} to 15 (cal / cm ^{3) 1/2} or 10 (cal / cm ^{3) 1/2} to 13 (cal / cm ³ ) &^Lt; ^/ RTI >

As the second monomer, a monomer selected from monomers known to have the above solubility parameter may be used.

For example, as the second monomer, a compound represented by the following formula (2) or (3) may be used.

(2)

Q is hydrogen or an alkyl group, U is an alkylene group, Z is a hydrogen or an alkyl group, and m is an arbitrary number.

(3)

In Formula (3), Q is hydrogen or an alkyl group, A and U are each independently an alkylene group, and X is a hydroxyl group or a cyano group.

As the alkyl group in Q and Z in formulas (2) and (3), an alkyl group having 1 to 20 carbon atoms, 1 to 16 carbon atoms, 1 to 12 carbon atoms, 1 to 8 carbon atoms or 1 to 4 carbon atoms may be used. The alkyl group may be linear, branched or cyclic. In addition, the alkyl group may be optionally substituted with one or more substituents.

In the general formulas (2) and (3), m and n are arbitrary numbers, for example, each independently is 1 to 100, 1 to 90, 1 to 80, 1 to 70, 1 to 60, 1 to 50, 1 to 40, To 30, from 1 to 20, from 1 to 16, or from 1 to 12.

In one embodiment, Q is hydrogen or an alkyl group having 1 to 4 carbon atoms, U is an alkylene group having 1 to 4 carbon atoms, Z is hydrogen or an alkyl group having 1 to 4 carbon atoms, and m Is about 1 to 20, but is not limited thereto.

The polymer may include 50 to 99.9 parts by weight of the first monomer polymerization unit and 0.1 to 20 parts by weight of the second monomer polymerization unit. In another embodiment, the first monomeric polymerization unit may be present in an amount of 60 to 99.9 parts by weight, 70 to 99.9 parts by weight, or 80 to 99.9 parts by weight in another example. The second monomer polymerization unit may be contained in an amount of 5 to 20 parts by weight or 7 to 20 parts by weight. Unless otherwise specified, the unit weight portion in the present application may mean a weight ratio between the respective components. In addition, the weight ratio of the monomer polymerization unit may be a weight ratio of the monomer used in the production of the polymer. Therefore, for example, when the polymer comprises 50 to 99.9 parts by weight of the first monomer polymerization unit and 0.1 to 20 parts by weight of the second monomer polymerization unit, the first monomer and the second monomer are mixed in a weight of 50 to 99.9: 0.1 to 20 May mean that the polymer mixture is formed by polymerizing the monomer mixture comprising the monomer (first monomer: second monomer). If the weight ratio of the second monomer in the polymer is less than 0.1 part by weight or the weight ratio of the first monomer is more than 99.9 parts by weight, resistance to oil solvent or endodiffic resistance may not be sufficient, and the weight ratio of the second monomer If the weight ratio of the first monomer is less than 50 parts by weight, the polymer may not be formed due to phase separation or the like, resistance to polar solvents, or resistance to perspiration or tears may not be sufficient.

In another example, the polymer may comprise at least 50%, at least 55%, at least 60%, at least 65%, at least 70%, at least 75%, or at least 80% by weight of the polymerized units of the first monomer. Wherein the ratio of the first monomeric polymerization units is 99% or less, 98% or less, 97% or less, 96% or less, 95% or less, 94% or less, 93% or less, 92% or less, 91% % ≪ / RTI > In the above state, the polymer may be such that the polymerization unit of the second monomer is 40 parts by weight or less, 35 parts by weight or less, 30 parts by weight or less, 25 parts by weight or less, 20 parts by weight 15 parts by weight or less, 10 parts by weight or less, or about 8 parts by weight or less. The polymerization unit of the second monomer may be contained in an amount of about 0.1 parts by weight or more, 0.15 parts by weight or more, 0.2 parts by weight or more, or 5 parts by weight or more based on 100 parts by weight of the polymerized units of the first monomer. Resistance to a polar solvent, resistance to perspiration or tears can be effectively ensured while securing the resistance to oil-based solvents and the resistance to an oil-based solvent at the above ratios.

The polymer may include additional monomers for imparting other functions besides the first and second monomers described above, for example, for controlling the glass transition temperature and the like.

That is, the polymer may be a compound containing a silicon atom, for example, a compound of the following formula (5) as a polymerization unit. The compound of the following formula (5) can form a siloxane bond in the polymer, and the siloxane bond affects the improvement of the cohesion of the polymer, and can contribute to improvement of the water resistance and oil resistance.

[Chemical Formula 5]

In Formula (5), R 1 to R 6 each independently represents a hydrogen atom, a hydroxy group, an alkyl group, an alkoxy group, an alkenyl group, a (meth) acryloyl group, a (meth) acryloylalkyl group, (Meth) acryloyloxy group or a (meth) acryloyloxyalkyl group, and at least one of them is an alkenyl group, a (meth) acryloyl group, a

Further, in the general formula (5), n is a number within the range of 0 to 20.

As the alkyl group or alkoxy group in the general formula (5), a linear, branched or cyclic alkyl group or alkoxy group having 1 to 20 carbon atoms, 1 to 16 carbon atoms, 1 to 12 carbon atoms, 1 to 8 carbon atoms or 1 to 4 carbon atoms may be exemplified, Which may optionally be substituted by one or more substituents.

As the alkenyl group in the general formula (5), a straight chain, branched chain or cyclic alkenyl group having 2 to 20 carbon atoms, 2 to 16 carbon atoms, 2 to 12 carbon atoms, 2 to 8 carbon atoms or 2 to 4 carbon atoms may be exemplified, Lt; / RTI > may be substituted by one or more substituents.

At least one of R 1 to R 6 in Formula (5) is a polymerizable functional group such as an alkenyl group, a (meth) acryloyl group, a (meth) acryloylalkyl group, a (meth) acryloyloxy group or a (meth) acryloyloxyalkyl group , And the compound may be contained in the polymer as a polymerization unit by such a functional group. The polymerizable functional group may be generally a (meth) acryloylalkyl group or a (meth) acryloyloxyalkyl group, and the alkyl group may have 1 to 20 carbon atoms, 1 to 16 carbon atoms, 1 to 12 carbon atoms , A substituted or unsubstituted straight-chain, branched-chain or cyclic alkyl group having 1 to 8 carbon atoms or 1 to 4 carbon atoms.

In Formula 5, at least one, more than two, or three of R 1 to R 6 may be an alkoxy group.

In one example, the compound of formula (5) is a compound wherein n is 0, R1, R3, R5, and R6 are each independently selected from the group consisting of hydrogen, alkyl groups, alkoxy groups, (meth) acryloylalkyl groups, At least one of R1, R3, R5 and R6 is an alkoxy group and at least one of R1, R3, R5 and R6 is a (meth) acryloyl group or a (meth) acryloyl group, Lt; / RTI > is a monooxyalkyl group. In this case, the alkyl group is an alkyl group having 1 to 8 carbon atoms, and the alkoxy group may be an alkoxy group having 1 to 8 carbon atoms.

In another example, the compound of Chemical Formula (5) is a compound wherein n is 1 or more and R 1 to R 6 are each independently hydrogen, an alkyl group, an alkoxy group, a (meth) acryloylalkyl group, or a (meth) acryloyloxyalkyl group , And at least one of R 1 to R 6 is a (meth) acryloylalkyl group or a (meth) acryloyloxyalkyl group. In this case, the functional groups other than the (meth) acryloylalkyl group or the (meth) acryloyloxyalkyl group in R 1 to R 6 may be an alkyl group. The alkyl group may be an alkyl group having 1 to 8 carbon atoms, and the alkoxy group may be an alkoxy group having 1 to 8 carbon atoms.

The polymer may include 50 to 99.9 parts by weight of the first monomer unit, 0.1 to 20 parts by weight of the second monomer unit, and 0.1 to 10 parts by weight of the polymer unit of the compound of the formula (5). If the ratio of the polymerization unit of the compound of the general formula (5) is too small, the effect of addition of the compound may be insufficient, for example, the effect of imparting gloss to the film or prevention of blurring may be insignificant. And may exhibit properties that are not suitable for formation.

In another example, the polymer may comprise at least 50%, at least 55%, at least 60%, at least 65%, at least 70%, at least 75%, or at least 80% by weight of the polymerized units of the first monomer. Wherein the ratio of the first monomeric polymerization units is 99% or less, 98% or less, 97% or less, 96% or less, 95% or less, 94% or less, 93% or less, 92% or less, 91% % ≪ / RTI > In the above state, the polymer has a polymerization unit of the compound of Formula 5 in an amount of 20 parts by weight or less, 15 parts by weight or less, 13 parts by weight or less, 10 parts by weight or less, By weight or less. The polymerization unit of the compound of Formula 5 is contained in a proportion of at least 0.1 part by weight, at least 0.15 parts by weight, at least 0.2 parts by weight, at least about 0.5 parts by weight or at least about 1 part by weight based on 100 parts by weight of the polymerized units of the first monomer . Resistance to a polar solvent, resistance to perspiration or tears can be effectively ensured while securing the resistance to oil-based solvents and the resistance to an oil-based solvent at the above ratios.

The polymer may be produced by a known polymerization method using the above-mentioned first and second monomers and a silicon atom-containing compound and other necessary monomers. In one example, the polymer may be prepared by a solution polymerization method using a solvent, for example, an organic solvent, for example, a radical solution polymerization method. For example, when the polymer is applied to a use in contact with the human body such as cosmetics, a solvent which is friendly to the human body can be selected and used in the polymerization process. Examples of such solvents include, but are not limited to, isododecane, isoparaffin, or isohexadecane.

In the present application, the polymer may have a weight average molecular weight (Mw) in the range of 10,000 to 500,000. The weight average molecular weight in the present application may be, for example, a conversion value relative to standard polystyrene measured using GPC (Gel Permeation Chromatograph), and unless otherwise specified, the term molecular weight may refer to a weight average molecular weight have. The molecular weight (Mw) as described above may be useful, for example, when the polymer is applied as a film-forming agent. It is possible to efficiently form a coating film without aggregation or the like by using the polymer in the molecular weight (Mw) range.

In addition, the polymer may have a glass transition temperature in the range of 10 ° C to 70 ° C. In the present application, the glass transition temperature is a theoretical value obtained from the monomer composition of the polymer through the so-called Fox equation. Such a glass transition temperature may be useful when the polymer is applied as a film forming agent. The polymer can be used in the range of the glass transition temperature to enable the formation of a film efficiently without tackiness or cracking.

The polymer of the present application as described above can exhibit low solubility in both polar and non-polar solvents. The term nonpolar solvent in the present application means a solvent having a dielectric constant at 25 ° C in the range of about 1 to about 3, about 1.5 to 2.5, or about 1.5 to 2, and the term polar solvent means 25 Quot; may mean a solvent in which the dielectric constant at < RTI ID = 0.0 > C < / RTI > is within the range of about 75 to about 85 or about 75 to 80. [ A typical example of the non-polar solvent includes hexane (dielectric constant (25 ° C): about 1.89), and a typical example of the polar solvent is water (dielectric constant (25 ° C): about 78.54) , But is not limited thereto. Well-known dielectric constants for the solvents are known for each solvent in the chemical field.

In one example, the polymer may have a solubility in the polar solvent of 10 or less or 5 or less. The polymer may have a solubility in the nonpolar solvent of 10 or less or 5 or less. The lower limit of the solubility means that the polymer is more resistant to polar and non-polar solvents, so that the lower limit of the solubility is not particularly limited. In the present application, the solubility in a specific solvent means the number of grams (g) of the polymer capable of being dissolved to the maximum of 100 g of the solvent. In addition, unless otherwise specified, the solubility in the present application means the solubility measured at ambient temperature. The term ambient temperature is a natural, non-warming or non-warming temperature, for example, a temperature within the range of about 10 ° C to 30 ° C, about 15 ° C to 30 ° C, or about 20 ° C to 30 ° C, Lt; RTI ID = 0.0 > 25 C. < / RTI >

The polymer may exhibit an appropriate solubility for a solvent in an intermediate stage of the polar and non-polar solvent. For example, the polymer may have a solubility of greater than 20 or greater than or equal to about 20 to about 50 for a solvent having a dielectric constant in the range of 4 to 15, 5 to 15, 5 to 10, or 5 to 8 at 25 ° C. Lt; / RTI > Examples of such solvents include, but are not limited to, ethyl acetate (dielectric constant (25 ° C): about 6.02).

Such a polymer may be used, for example, as a film former. Such a polymer can form a uniform film (coating) by application or the like, exhibits high stability even when it is applied to skin or the like, exhibits resistance to both polar and non-polar solvents and can be used in various solvents such as sweat, It is possible to exhibit excellent resistance to the above.

Accordingly, the polymer can be used in the manufacture of various cosmetics including nail polish, lipstick, eye shadow, styling agent for hair, eye liner, etc. that can be applied to makeup of mascara and the like applied to the cosmetic pack, And can be applied to the production of film formers or compositions for cosmetics. In addition, the polymer or film forming agent can be applied to medicines by the above-mentioned characteristics. Examples of medicinal uses include bandages and transdermal absorption preparations.

The proportion of the polymer in the external preparation for skin, the cosmetic composition or the mascara composition is not particularly limited and may be selected in consideration of the application and the like. For example, the polymer may be included in the skin topical composition, cosmetic composition or mascara composition at a ratio within a range of about 1% to 20% by weight.

The external preparation for skin, the cosmetic composition or the mascara composition may further contain other active ingredients depending on the use. Examples of the additional effective ingredient include not only cosmetic ingredients such as whitening and ultraviolet ray shielding but also active ingredients, physiologically active ingredients, and pharmacologically active ingredients. Examples of such effective components include local anesthetic components (lidocaine, dibucaine hydrochloride, dibucaine, ethyl benzoate), analgesic components (salicylic acid derivatives such as methyl salicylate, indomethacin, piroxycam, ketoprofen, Etc.), antiinflammatory components (glycyrrhetinic acid, glycyrrhizinic acid salts such as dipotassium glycyrrhizinate, glycyrrhetinic acid, stearyl glycyrrhetinate, bepsiamark, benzyl nicotinate, hydrocortisone, hydrocortisone, Dicamethasone, dexamethasone acetate, dimethylisopropyl azelene propionate, alnica extract, golden extract, toad extract, chamomile extract, carrageenan, acaric acid hydrocortisone, valproic acid acetic acid prednizone, Ginseng extract, licorice extract, guaiazulene, gardenia extract, gentian extract, black tea extract, tocopherol, tocopheryl acetate, carrot extract, (Antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, antioxidants, , Ammonia, l-menthol dl-can pool, peppermint oil, nicotinic acid benzyl, nonylic acid waniramide and the like), zinnia ingredient (crotonic acid (Iodine), iodide, potassium iodide, merbromin, oxyder, cresol, tricholinic acid, etc.), antiseptic or disinfecting components (acinol, chlorhexidine gluconate, chlorhexidine hydrochloride, benzalkonium chloride, benzethionium chloride, povidone iodide, , Phenol, isopropylmethylphenol, thymol, sodium salicylate, undecylenic acid, photosensor, hinokitiol, phenoxyethanol, chlorobutanol, quaternium 73, chinpyrithione, paraoxybenzoic acid esters, eucalyptus extract, resorcinol rosemary extract, etc.), antifungal compounds (such as clotrimazoacetate, crotriamazoate, myconazole acetate, eicosanol acetate, Imidazole antifungal agents such as oxycodone acetate, oxaconazole acetate, sorconosuric acid hydrochloride, Nechikonajor hydrochloride, biponazole and thioconazole, and acomoxanthorrhic acid, allyl amines such as terbinafine, terbinafine hydrochloride and naftifine Benzylamine-based antifungal agents such as amine-based antifungal agents and butenaphin, allylamine-based antifungal agents such as amorphous hydrochloride, thiocarbamate-based antifungal agents such as tranafate and tricylate, pyrrolitrin, Vitamin A 2 palmitate, vitamin D2, retinol acetate, retinol, vitamin A oil, panthenol, etc.), convergent components (acid, Glycerin, concentrated glycerin, potassium hydroxide, salicylic acid, salicylic acid, glycerin, glycerin, glycerin, glycerin, glycerin, (Butylene glycol, sodium pyrrolidonecarboxylate, propylene glycol, sodium ribonucleic acid, myrtle extract, asuragic acid, alanine, arginine alginate Hydrolyzed collagen, hydrolyzed collagen, hydrolyzed egg shell, hydrolyzed egg white, hydrolyzed silk, algae extract, chrysanthemum extract, kiwi extract Kiss, xylitol, chitosan, cucumber extract, kuinsseedekisu, glycine, glycerin, glucose, caprolaoe extract, cystin, cysteine, A lotion, an extract of lycopene, an extract of lychee, an apple extract, a royal jelly extract, etc.) were added to a molybdate solution Ingredients (almond oil, avocado oil, olive oil, oleic acid, orange raffia oil, cacao oil, carrot acid, squalane, ceramide, evening primrose oil, grape seed oil, jojoba oil, macadamia nut oil, mineral oil, mink oil, eucalyptus oil, Oil, and lanolin), whitening components (ascorbic acid, ascorbic acid derivatives, arbutin, lecithin, eragic acid, glutathione, kojic acid, age cane kiss, kiwi extract, etc.) Ethyl ester of p-aminobenzoic acid, amyl alcohol of paradimethylaminobenzoic acid, Ethylhexyl alcohol ester of terpara dimethylamino benzoic acid, t-butylmethoxydibenzoylmethane, oxybenzyne, octyltriazone, octyl salicylate, ethyl diisopropylpropionate, methyl diisopropylpropionate, synokisite, dimethoxy Octyl methoxycinnamate, octyl methoxycinnamate, etc.), herbal extract components (such as glyceryl octanoate, glyceryl octanoate, dimethoxybenzylidene dioxoimidazolidinone octylate, chestnut extract, drometrizol, paramethoxycarboxylic acid isopropyl, , Vitamins, amino acids, or minerals. However, the present invention is not limited thereto.

The external preparation for skin, cosmetic composition or mascara composition may contain other solvent, solvent or additive depending on the use.

Examples of the solvent or solvent component may include, but are not limited to, alcohols (e.g., polyethylene glycol), ethers (such as diethyl ether and the like, glycol ethers such as methyl cellosolve, etc.) (Acetonitrile, etc.), ketones (acetone, etc.) or esters (e.g., carboxylic acid alkyl esters such as ethyl acetate, etc.) ) Can be exemplified.

Examples of the additives include publicly known components such as a plasticizer, a wetting agent, a defoaming agent, a colorant, a preservative, a fragrance, a flavoring agent, a pigment or a thickener as well as an ingredient for use in quasi-drugs, medicines or cosmetics such as a powdery base or carrier (Base oil, wax, petroleum jelly, paraffin oil, silicone oil, higher fatty acid ester or higher fatty acid), aqueous base or carrier (gel base such as xanthan gum, etc.) Etc.), a preservative, a chelating agent, an antioxidant, a coolant, a stabilizer, a fluidizing agent, an emulsifier, a tackifier, a buffering agent, a dispersant, an adsorbent, a humectant, a humectant, a desiccant, Olefin resins such as polybutene), and the like, but the present invention is not limited thereto.

The method for manufacturing the external preparation for skin, the cosmetic composition or the mascara composition using the above-mentioned components or, if necessary, further other known components is not particularly limited and a known method can be applied.

The present application can provide a composition for external application for skin, a cosmetic composition or a mascara composition to which a functional polymer having low solubility for polar and non-polar solvents and having a low bleeding characteristic for the solvent is applied. The composition to which the polymer is applied may exhibit resistance to various solvents such as sebum, perspiration and tears, so that the sustainability of make-up and the like can be effectively maintained.

Hereinafter, the composition for external application for skin and the like of the present application will be specifically described by way of Examples and Comparative Examples, but the scope of the composition is not limited to the following Examples. In the following Examples and Comparative Examples, physical properties were evaluated in the following manner.

1. Measurement of solubility of polymer

The polymer solution prepared in Example or Comparative Example was kept at a temperature of about 150 캜 for about 60 minutes to volatilize the solvent. Subsequently, 1 g of the volatilized polymer is collected. Subsequently, 1 g of the collected polymer was added to 5 g of a solvent (hexane, ethyl acetate, acetone or water), stirred at room temperature for 30 minutes, and then the undissolved residual polymer was removed. The clear solution from which the residual polymer had been removed was collected, dried at 150 ° C for 30 minutes to remove the solvent, and the solid content was calculated through mass comparison. The concentration of the polymer dissolved in the solvent was measured through the solid content, and the solubility was calculated by converting the measured amount into the value for 100 g of the solvent. If the solution was not transparent after removing the residual polymer, the solution was passed through a filter (0.45 탆 NYLON) to obtain a clear solution and then the above procedure was performed.

<Evaluation Criteria for Solubility>

A: Solubility of 15 or more

B: Solubility of more than 10, less than 15

C: Solubility of more than 5, less than 10

D: Solubility of 5 or less

2. Molecular weight measurement

The weight average molecular weight (Mw) and the molecular weight distribution (PDI) were measured using GPC under the following conditions, and the measurement results were converted into standard polystyrene of the Agilent system for the calibration curve.

<Measurement Conditions>

Measuring instrument: Agilent GPC (Agilent 1200 series, U. S.)

Column: Two PL Mixed B connections

Column temperature: 40 ° C

Eluent: THF (Tetrahydrofuran)

Flow rate: 1.0 mL / min

Concentration: ~ 1 mg / mL (100 μL injection)

3. Estimation of glass transition temperature

The glass transition temperature (Tg) was calculated by the following formula according to the monomer composition.

<Formula>

1 / Tg =? Wn / Tn

In the above formula, Wn is the weight fraction of each monomer in the polymer, Tn is the glass transition temperature that occurs when the monomer forms a homopolymer, and the right side of the formula indicates the weight fraction of the monomer used to form the homopolymer (Wn / Tn) divided by the glass transition temperature in the case where the glass transition temperature (Tg) was measured for each monomer.

4. sebum blurring test

The polymer prepared in each Preparation Example was dissolved in isododecane as a solvent at a concentration of about 10% by weight, ceresine, synthetic wax and microcrystalline wax were dissolved in 7 wt% %, 6 wt% and 8 wt%, respectively, at a temperature of about 90 캜 to prepare a composition A. Subsequently, propylene carbonate and distearmonium hectorite were added to the composition A at a concentration of 8 wt% and 2 wt%, respectively, and the mixture was uniformly dispersed for 20 minutes to prepare a composition B. Subsequently, iron oxide (CI 77499) is added at a concentration of 6% by weight, preservatives are added in an appropriate amount, dispersed for 30 minutes, and slowly cooled to about 28 캜 to prepare a mascara formulation .

The sebum blurring test using the manufactured mascara formulation was carried out in an in-vitro test and an in-vivo test, and the details are as follows.

In-vitro testing

The mascara formulation is applied to a slide glass (glass plate) to a thickness of 30 탆, and is then completely dried at room temperature. After drying, 0.1 g of water and 0.1 g of sebum were each dropped on the mascara, left for 20 minutes, put on a cotton pad, and reciprocated 30 times at a force of 200 gf. .

<Evaluation Criteria>

When a comparison was made on a scale within the range of 0 to 5 according to the degree of the appearance on the cotton wool, the case where no mascara was observed on the cotton wool was designated as 5, and the case where the polymer of Comparative Example 1 was applied was referred to as a reference. , And the superior level to the control group was quantified to the first decimal place by a relative comparison between the samples.

In-vivo testing:

The prepared mascara formulations were applied to the subject's eyelashes, and images were taken after 6 hours, and compared and evaluated according to the following criteria.

<Evaluation Criteria>

After 6 hours, images are taken and the blurring area is analyzed by image analysis. The area of blur at the time of image analysis is expressed in units of pixels.

5. Water resistance test

The dried mascara formulations were applied to a slide glass (glass plate) to a thickness of 30 탆 and dried thoroughly at room temperature. The dried sample was immersed in water at room temperature for about 30 minutes and then taken out to obtain a mass reduction rate (= B is the total mass of the slide glass coated with the mascara formulation, and B is the total mass of the slide glass measured after removing the water after being immersed in water, The water resistance is evaluated according to the standard.

<Evaluation Criteria>

A: When the mass reduction rate is 5% or less

B: If the mass reduction rate exceeds 5%

6. NMR Evaluation Method

0.1 g of the polymer solution prepared in the Example or Comparative Example was taken out and dissolved in 1 mL of the following NMR solvent. 1 H-NMR was measured using the following analytical instrument according to the manufacturer's manual, You can see the conversion rate. For example, in the presence of an unpolymerized monomer, a -H peak derived from = CH2 of the double bond end in the &lt; 1 &gt; H-NMR spectrum is confirmed at about 5.7 ppm to 6.4 ppm, and -H The area of the peak can be used to identify the constituents of the polymer.

<Measurement Conditions>

Analytical instrument: 500 MHz NMR (Varian Unity Inova 500), 1 H-NMR

Concentration: 10 to 20 mg / mL, solvent: CDCl3-d3

Temperature: 25 ℃

Examples 1 to 3 and Comparative Examples 1 to 3

The monomers for the preparation of the polymers were applied in the types and ratios shown in Table 1 below. As shown in the following Table 1, the monomers were mixed and then added to a solvent such as isododecane at a monomer concentration of 35% by weight. Further, an appropriate amount of a thermal initiator (V-65, 2,2'-azobis Then, the reaction vessel is sealed with stirring, and the dissolved oxygen is removed by bubbling with nitrogen at room temperature for about 30 minutes, and the oxygen-depleted reaction mixture is cooled to a temperature of about 70 ° C. When the temperature rises to 70 ° C., the polymerization reaction proceeds by the thermal initiator dissolved in the solvent. After the reaction has been carried out for about 24 hours, the temperature (TMSS in Comparative Example 3 corresponds to MQ-1600 Resin of Dow Corning).

Example Comparative Example One 2 3 One 2 3 Polymer A B C D E F LMA 19 16 19 EHMA 29 30 IBOMA 69 60 69 60 71 EOEOEA 10 10 10 10 10 KBM-503 One KBE-503 2 5 TMSS 100 Content Unit: g
LMA: lauryl methacrylate (single polymer solubility parameter: 8.2 (cal / cm ³ ) ^1/2 )
EHMA: ethylhexyl methacrylate (single polymer solubility parameter: 8.3 (cal / cm ³ ) ^1/2 )
IBOMA: isobornyl methacrylate (single polymer solubility parameter: 8.1 (cal / cm ³ ) ^1/2 )
EOEOEA: ethoxyethoxy ethylacrylate (single polymer solubility parameter: 10.6 (cal / cm ³ ) ^1/2 )
KBE-503: 3-methacyloxypropyl triethoxysilane
KBM-503: 3-methacyloxypropyl trimethoxylsilane
TMSS: trimethylsiloxysilicate (single polymer solubility parameter: 7.5 (cal / cm ³ ) ^1/2 ) (Trimethyl siloxysilicate: Dow Corning MQ-1600 Resin)

1. NMR evaluation results

Fig. 1 shows NMR analysis results for the polymer of Example 1. Fig. As can be seen from the figure, the analysis of the polymer of Example 1 revealed that almost no 1H peak derived from = CH2 of the double bond end was observed, indicating that the polymerization was effectively carried out. Further, from the monomer (LMA), IBOMA and KBE-503 which form the polymer, -CH2- and -CH- peaks adjacent to -COO-, and from the -OCH2CH2O- peak of EOEOEA and SiO (CH2-) 3 of KBE-503 The derived peak was identified as an area value of 10 in the 4.7 to 3.3 ppm range. A peak derived from -CH 3 derived from the side chain and -CH 3 derived from the meta position was identified as an area value of 35 in the range from 2.0 ppm to 1.5 ppm and a 1HCH -CH 2 CH- or -CH 2 CH 2 derived from the polymer main chain was found to be 1.5 ppm And an area value of 55 to 0.5 ppm.

Also in the case of Example 2, as a result of NMR evaluation, 1H peak derived from = CH2 of the double bond end was hardly recognized. Peaks derived from EHMA, IBOMA and KBM-503 forming a polymer, -CH-peak adjacent to -COO-, -OCH2CH2O- from EOEOEA, and peaks derived from -Si-O (CH3) 3 of KBM- The area value in the 5.0 ppm to 3.5 ppm region was found to be 9. Also, a peak having an area value of 36 in the range of 2.5 ppm to 1.3 ppm from -CH 3 derived from -CH 2 - and meta position of the side chain was confirmed, and the 1H area value determined from -CH 2 CH- or -CH 2 CH 2 - derived from the polymer main chain And 55 in the 1.3 ppm to 0.5 ppm region.

In the case of the polymer of Example 3, analysis by the procedure according to the 1 H-NMR evaluation method revealed that almost no 1H peak derived from = CH2 of the double bond end was observed. -CH 2 - and -CH- peaks adjacent to -COO-, -OCH 2 CH 2 O- peaks of EOEOEA and -SiO (CH2-) 3 -derived peaks of KBE-503 of LMA, IBOMA and KBE- The area value in the ppm area was 11. A peak having an area value of 35 in the region of 2.0 ppm to 1.5 ppm from -CH 3 derived from the side chain and -CH 3 derived from the meta position was confirmed and the 1H area value determined from -CH 2 CH- or -CH 2 CH 2 - derived from the polymer main chain was 1.5 ppm To 0.5 ppm.

In the case of the polymer of Comparative Example 1, 1H 1H derived from = CH2 of the double bond was hardly observed, and EHMA formed from the polymer and IBOA-COO-adjacent -CH- peak, EOEOEA -OCH2CH2O- And an area value of 9 in the range of from 5.0 ppm to 3.5 ppm. A peak of an area value of 35 in the region of 2.5 ppm to 1.3 ppm from -CH 3 derived from the side chain and -CH 2 derived from the meta position was confirmed and the 1H area value found from -CH 2 CH- or -CH 2 CH 2 - derived from the polymer main chain was 1.3 ppm To 56 in the 0.5 ppm region.

In the case of the polymer of Comparative Example 2, 1H 1H derived from = CH2 of the double bond was hardly recognized, and LMA formed of a polymer and -COO- adjacent -CH 2 - and -CH- peaks of IBOMA and -OCH 2 CH 2 O of EOEOEA And the area value was found to be 10 in the range of 4.7 to 3.3 ppm. In addition, a peak having an area value of 32 in the range of from 2.0 ppm to 1.5 ppm from -CH2- in the side chain and -CH3 derived from the meta position was confirmed, and the 1H area value found from -CH2CH- or -CH2CH2- derived from the polymer main chain was And was 58 at 1.5 ppm to 0.5 ppm.

2. Property evaluation

The results of measuring the physical properties of the polymers of Examples and Comparative Examples are summarized in Table 2 below.

Example Comparative Example One 2 3 One 2 3 Polymer A B C D E F
Solubility

Hexane D D D D C A Ethyl acetate A A A A A A Acetone D D D C C A water D D D D C C Weight average molecular weight 20 million 35 million 25 million 34 million 20 million Glass transition temperature (캜) 31 39 32 39 34 sebum
Smear In vitro 4.2 4.2 4.5 3.9 4.0 3.0 In vivo 2000 2100 1700 3200 3100 4500 Water resistance test A A A A A A

From the above results, it can be seen that the polymer used in the present application exhibits low solubility in polar and non-polar solvents and is suitable for film formation having low bleeding characteristics with respect to the solvent, A cosmetic composition or a mascara composition can be provided which can exhibit resistance to various solvents and can maintain the durability of make-up and the like effectively.

Claims (16)

50 to 99.9 parts by weight of a first monomeric polymerized unit having a solubility parameter of the single polymer of less than 10.0 (cal / cm &lt; ³ &gt;)^1/2; 0.1 to 20 parts by weight of a second monomeric polymerized unit in which the solubility parameter of the single polymer is 10.0 (cal / cm &lt; ³ &gt;) ^1/2 or more; And 0.1 to 10 parts by weight of a polymerized unit of the compound of the formula (5)
Wherein the polymer has a solubility at room temperature of 10 or less for a solvent having a dielectric constant (25 DEG C) within a range of 75 to 85;
[Chemical Formula 5]

In formula (5), R ₁ to R ₆ each independently represents a hydrogen atom, a hydroxy group, an alkyl group, an alkoxy group, an alkenyl group, a (meth) acryloyl group, a (meth) acryloylalkyl group, (Meth) acryloyloxy group or a (meth) acryloyloxyalkyl group, and n is an integer of 0 to 3, and at least one of them is an alkenyl group, (meth) acryloyl group, 20. &Lt; / RTI &gt; The composition of claim 1, wherein the first monomer has a solubility parameter of the single polymer within a range of 5 (cal / cm ³ ) ^1/2 to 9.5 (cal / cm ³ ) ^1/2 . The external preparation for skin according to claim 1, wherein the first monomer is a compound represented by the following formula (1):
[Chemical Formula 1]

In Formula (1), Q is hydrogen or an alkyl group, and B is a linear or branched alkyl group having 5 or more carbon atoms, an alicyclic hydrocarbon group or an aromatic substituent group. The composition for external application for skin according to claim 3, wherein Q in the formula (1) is hydrogen or an alkyl group having 1 to 4 carbon atoms, and B is an alkyl group having 7 or more carbon atoms or an alicyclic hydrocarbon group having 6 to 12 carbon atoms. The composition of claim 1, wherein the second monomer has a solubility parameter of the single polymer within a range of 10.0 (cal / cm ³ ) ^1/2 to 15.0 (cal / cm ³ ) ^1/2 . The external preparation for skin according to claim 1, wherein the second monomer is a compound represented by the following formula (2) or (3):
(2)

Q is hydrogen or an alkyl group, U is an alkylene group, Z is a hydrogen or an alkyl group, and m is an arbitrary number.
(3)

In the formula (3), Q is hydrogen or an alkyl group, A and U are each independently an alkylene group, X is a hydroxyl group or a cyano group, and n is a number in the range of 1 to 100. A compound according to claim 6, wherein Q is hydrogen or an alkyl group having 1 to 4 carbon atoms, U is an alkylene group having 1 to 4 carbon atoms, Z is hydrogen or an alkyl group having 1 to 4 carbon atoms, Of the total amount of the composition. The composition for external application for skin according to claim 1, wherein at least one of R ₁ to R ₆ in formula (5) is an alkoxy group. And n is 0, and R ₁ , R ₃ , R ₅ and R ₆ are each independently hydrogen, an alkyl group, an alkoxy group, a (meth) acryloylalkyl group or a (meth) acryloyl group. oxy alkilgiyi be, R _1, R _3, R ₅ and R at least one of ₆ alkoxy group, and R _1, R _3, R ₅ and R ₆ at least one of which is a (meth) acryloyl group or (meth) Wherein the composition is an acryloyloxyalkyl group. And R ₁ to R ₆ are each independently an alkyl group, a (meth) acryloylalkyl group or a (meth) acryloyloxyalkyl group, and R ₁ to R ₆ Is a (meth) acryloylalkyl group or a (meth) acryloyloxyalkyl group. delete The composition for external application for skin according to claim 1, wherein the polymer has a glass transition temperature in the range of 10 ° C to 70 ° C. The composition for external application for skin according to claim 1, wherein the polymer has a solubility at room temperature of 10 or less for a solvent having a dielectric constant (25 ° C) within a range of 1 to 3. The composition for external application for skin according to claim 1, wherein the polymer has a solubility at room temperature of not less than 15 for a solvent having a dielectric constant (25 ° C) within a range of 4 to 15. 50 to 99.9 parts by weight of a first monomeric polymerized unit having a solubility parameter of the single polymer of less than 10.0 (cal / cm &lt; ³ &gt;)^1/2; 0.1 to 20 parts by weight of a second monomeric polymerized unit in which the solubility parameter of the single polymer is 10.0 (cal / cm &lt; ³ &gt;) ^1/2 or more; And 0.1 to 10 parts by weight of a polymerized unit of the compound of the formula (5)
Wherein the polymer has a solubility at room temperature of 10 or less for a solvent having a dielectric constant (25 ° C) within a range of 75 to 85:
[Chemical Formula 5]

In formula (5), R ₁ to R ₆ each independently represents a hydrogen atom, a hydroxy group, an alkyl group, an alkoxy group, an alkenyl group, a (meth) acryloyl group, a (meth) acryloylalkyl group, (Meth) acryloyloxy group or a (meth) acryloyloxyalkyl group, and n is an integer of 0 to 3, and at least one of them is an alkenyl group, (meth) acryloyl group, 20. &Lt; / RTI &gt; 50 to 99.9 parts by weight of a first monomeric polymerized unit having a solubility parameter of the single polymer of less than 10.0 (cal / cm &lt; ³ &gt;)^1/2; 0.1 to 20 parts by weight of a second monomeric polymerized unit in which the solubility parameter of the single polymer is 10.0 (cal / cm &lt; ³ &gt;) ^1/2 or more; And 0.1 to 10 parts by weight of a polymerized unit of the compound of the formula (5)
Wherein the polymer has a solubility at room temperature of less than 10 for a solvent having a dielectric constant (25 ° C) in the range of from 75 to 85 mascara composition:
[Chemical Formula 5]

In formula (5), R ₁ to R ₆ each independently represents a hydrogen atom, a hydroxy group, an alkyl group, an alkoxy group, an alkenyl group, a (meth) acryloyl group, a (meth) acryloylalkyl group, (Meth) acryloyloxy group or a (meth) acryloyloxyalkyl group, and n is an integer of 0 to 3, and at least one of them is an alkenyl group, (meth) acryloyl group, 20. &Lt; / RTI &gt;