KR101716774B1 - A pill indicating bowel cativity effect and the manufacturing method of it - Google Patents

A pill indicating bowel cativity effect and the manufacturing method of it Download PDF

Info

Publication number
KR101716774B1
KR101716774B1 KR1020140018264A KR20140018264A KR101716774B1 KR 101716774 B1 KR101716774 B1 KR 101716774B1 KR 1020140018264 A KR1020140018264 A KR 1020140018264A KR 20140018264 A KR20140018264 A KR 20140018264A KR 101716774 B1 KR101716774 B1 KR 101716774B1
Authority
KR
South Korea
Prior art keywords
weight
ring
glutinous rice
drying
washing
Prior art date
Application number
KR1020140018264A
Other languages
Korean (ko)
Other versions
KR20150087769A (en
Inventor
윤병재
김학종
Original Assignee
주식회사 에이치씨바이오텍
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 에이치씨바이오텍 filed Critical 주식회사 에이치씨바이오텍
Publication of KR20150087769A publication Critical patent/KR20150087769A/en
Application granted granted Critical
Publication of KR101716774B1 publication Critical patent/KR101716774B1/en

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/09Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/01Instant products; Powders; Flakes; Granules
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/40Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by drying or kilning; Subsequent reconstitution
    • A23L3/44Freeze-drying

Abstract

본 발명은 배변활동개선에 효과가 있는 참다래환 및 그 제조방법에 대한 것으로서, 더욱 상세하게는 식이섬유가 풍부한 참다래를 이용하여 배변활동개선에 효과가 있고, 쉽고 편하게 먹을 수 있는 환 및 그 제조방법에 관한것이다.
본 발명은 이물질을 제거하기 위해 참다래, 함초, 대두, 질경이, 무화과를 세척하는 세척단계와, 상기 세척단계에서 세척된 참다래와 무화과는 동결건조하고, 함초와 질경이는 냉풍건조하는 건조단계와, 상기 세척단계에서 세척된 대두를 볶는 볶음단계와, 상기 건조단계에서 건조된 참다래, 함초, 질경이, 무화과와 상기 볶음단계에서 볶은 대두를 100~200mesh로 분쇄하는 분쇄단계와, 정제수 85~90중량%에 찹쌀 10~15중량%를 넣고 끓이는 찹쌀죽 제조단계와, 상기 분쇄단계에서 분쇄된 참다래 분말 26.4~31.4중량%와, 함초 분말 13.89~17.89중량%와, 대두 분말 13.89~17.89중량%와, 질경이 분말 4.86~7.86중량%와, 무화과 분말 2.55~5.55중량%와, 유산균(Bacillus velezensis) 0.01~0.02중량%에 상기 찹쌀죽 제조단계에서 제조된 찹쌀죽 26.4~31.4중량%를 부어 혼합한 후 반죽하는 혼합반죽단계와, 상기 혼합반죽단계에서 반죽한 시료를 환으로 만드는 환 성형단계와, 상기 환 성형단계에서 성형된 환을 70~90℃에서 건조시키는 환 건조단계를 포함하는 것을 특징으로 한다.
본 발명에 의하면 식이섬유가 풍부한 참다래를 이용하여 배변활동개선에 효과가 있고, 쉽고 편하게 먹을 수 있는 환을 제조할 수 있게 된다.
More particularly, the present invention relates to a quinceanula which is effective for improving bowel activity and a method for producing the same, and more particularly, .
The present invention relates to a method for removing foreign matter, comprising the steps of: washing the stems of kiwi, green tea, soybean, plantain, and fig, washing the stems and the figs washed in the washing step, lyophilized, A step of roasting the washed soybeans in the washing step, a step of pulverizing 100 to 200mesh of roasted soybeans, which are dried in the drying step, in a range of 85 to 90% by weight of purified water, And 10 to 15% by weight of glutinous rice, 26.4 to 31.4% by weight of powdered quince seeds pulverized in the pulverization step, 13.89 to 17.89% by weight of green tea powder, 13.89 to 17.89% by weight of soybean powder, (26.4 ~ 31.4% by weight) of glutinous rice bran prepared in the step of making the glutinous rice briquettes was mixed with 4.86 ~ 7.86% by weight of glutinous rice bran, 2.55 ~ 5.55% by weight of fig powder and 0.01 ~ 0.02% by weight of lactic acid bacterium (Bacillus velezensis) Kneading stage And, the ring and the shaping step to create a sample dough in the kneading step to the ring, the ring formed by the ring forming step; and a ring drying step of drying at 70 ~ 90 ℃.
According to the present invention, it is possible to produce a ring which is effective in improving bowel movement and which can be eaten easily and easily, by using a dietary fiber-rich quail.

Description

배변활동개선에 효과가 있는 참다래환 및 그 제조방법{A pill indicating bowel cativity effect and the manufacturing method of it} BACKGROUND OF THE INVENTION 1. Field of the Invention [0001] The present invention relates to a chewing gum,

본 발명은 배변활동개선에 효과가 있는 참다래환 및 그 제조방법에 대한 것으로서, 더욱 상세하게는 식이섬유가 풍부한 참다래를 이용하여 배변활동개선에 효과가 있고, 쉽고 편하게 먹을 수 있는 환 및 그 제조방법에 관한것이다. More particularly, the present invention relates to a quinceanula which is effective for improving bowel activity and a method for producing the same, and more particularly, .

변비는 임상에서 관찰되는 가장 흔한 증상 중 하나로 전 인구의 5~20%에서 호소될 만큼 자주 경험하지만 환자마다 표현하는 내용이 매우 다양하여 하나의 증상군이기 때문에 객관적으로 정의하기 쉽지 않다. 만성변비는 삶의 질을 저해하고 결장 및 직장암을 유발하는 위험성과 관련이 있는 것으로 보고되고 있다. 이러한 변비의 치료에 있어서 가장 중요한 것은 식이요법으로, 충분한 식이섬유 섭취는 변비의 예방 및 치료에 가장 적합하다. 일차적으로 상용할 수 있는 것으로 장내 효소에 소화되지 않는 식물 성분이며 대장 내에서 물을 흡수하여 변을 연하게 하고 부피를 크게 한다. 이에 따라 식이섬유가 풍부한 야채 및 과일을 이용한 변비개선제품의 개발이 크게 증가하고 있다. Constipation is one of the most common symptoms observed in clinical practice. It occurs frequently in 5-20% of the whole population, but it is difficult to define objectively because it is a symptom group because the contents of each patient are very diverse. Chronic constipation is reported to be associated with the risk of impairing quality of life and causing colon and rectal cancer. Most important in the treatment of constipation is diet, and adequate dietary fiber intake is most appropriate for the prevention and treatment of constipation. It is a plant ingredient that can not be digested in intestinal enzymes and absorbs water in the colon to soften the stomach and increase its volume. As a result, the development of constipation-improving products using vegetables and fruits rich in dietary fiber is greatly increasing.

본 발명의 주원료인 참다래(Kiwifruit)는 다래나무과(Actanidiaceae), 다래속(Actinidia)에 속하며, 온대지역에서 자라는 자웅이주의 덩굴성 낙엽과수이며, 대한민국에는 1990년대 말 뉴질랜드에서 종자를 도입하여 제주지역 및 남해안 일대에서 생산되고 있다. 참다래는 식이섬유, 비타민 C 함량이 높으며, 칼슘, 마그네슘, 인 등의 무기질 함량도 풍부하여 영양학적으로 우수하다고 알려져 있다. Kiwifruit, which is the main ingredient of the present invention, belongs to Actanidiaceae and Actinidia, and is a vine lance and water number in the temperate region. In Korea, seeds were introduced in New Zealand in the late 1990s, And is produced in the southern coastal area. Dietary fiber and vitamin C contents are high in kiwifruit, and it is known that it is rich in nutrients such as calcium, magnesium and phosphorus.

대한민국 등록특허 제10-0583876호에서는 당뇨병 환자의 식이를 위한 참다래 열매 추출물이 함유된 건강기능식품에 관하여 제시하고 있으며, 등록특허 제10-0615389호에서는 다래 추출물을 함유하는 알러지성 질환 및 비알러지성염증 질환의 예방 및 개선용 건강 기능 식품에 관하여 제시하고 있다. 또한 등록특허 제10-1249892호에서는 다미사 등의 천연재료를 이용한 배변촉진용 환의 제조방법에 관하여 제시하고 있다. Korean Patent No. 10-0583876 discloses a health functional food containing a fruit extract of kiwifruit for the diet of diabetic patients. In Patent No. 10-0615389, there is disclosed an allergenic disease and nonallergic And health functional foods for prevention and improvement of inflammatory diseases. In addition, Japanese Patent Registration No. 10-1249892 discloses a manufacturing method of a pancreatic pancreatic pancreas using natural materials such as Damasa.

본 발명은 배변활동개선에 효과가 있는 참다래환 및 그 제조방법을 제공하는 것이다. It is an object of the present invention to provide a poultry poultry which is effective in improving bowel activity and a method for producing the same.

본 발명에 따른 배변활동개선에 효과가 있는 참다래환의 제조방법은 이물질을 제거하기 위해 참다래, 함초, 대두, 질경이, 무화과를 세척하는 세척단계와, 상기 세척단계에서 세척된 참다래와 무화과는 동결건조하고, 함초와 질경이는 냉풍건조하는 건조단계와, 상기 세척단계에서 세척된 대두를 볶는 볶음단계와, 상기 건조단계에서 건조된 참다래, 함초, 질경이, 무화과와 상기 볶음단계에서 볶은 대두를 100~200mesh로 분쇄하는 분쇄단계와, 정제수 85~90중량%에 찹쌀 10~15중량%를 넣고 끓이는 찹쌀죽 제조단계와, 상기 분쇄단계에서 분쇄된 참다래 분말 26.4~31.4중량%와, 함초 분말 13.89~17.89중량%와, 대두 분말 13.89~17.89중량%와, 질경이 분말 4.86~7.86중량%와, 무화과 분말 2.55~5.55중량%와, 유산균(Bacillus velezensis) 0.01~0.02중량%에 상기 찹쌀죽 제조단계에서 제조된 찹쌀죽 26.4~31.4중량%를 부어 혼합한 후 반죽하는 혼합반죽단계와, 상기 혼합반죽단계에서 반죽한 시료를 환으로 만드는 환 성형단계와, 상기 환 성형단계에서 성형된 환을 70~90℃에서 건조시키는 환 건조단계를 포함한다. The method for manufacturing the chondrites according to the present invention is characterized in that the chondrites and figs washed in the washing step are lyophilized, , Green tea and plantain are dried in a cold air drying step, roasted soybean roasted in the washing step, and roasted soy sauce in a range of 100-200 mesh dried roasted chinese cabbage, green tea, plantain, A step of preparing glutinous rice bran by adding 10-15 wt% of glutinous rice to 85-90 wt% of purified water, 26.4 ~ 31.4 wt% of powdered quince seeds pulverized in the pulverization step, 13.89 ~ 17.89 wt% of green tea powder, Of soybean powder, 13.89 to 17.89 wt% of soybean powder, 4.86 to 7.86 wt% of plantain powder, 2.55 to 5.55 wt% of fig powder and 0.01 to 0.02 wt% of lactic acid bacterium (Bacillus velezensis) A mixing kneading step of mixing 26.4 to 31.4% by weight of rice husk by pouring and kneading the kneaded mixture, and a kneading step of kneading the kneaded sample in the kneading step, And a pneumatic drying step.

또한, 본 발명은 상기의 제조방법에 의해 제조되는 배변활동개선에 효과가 있는 참다래환을 제공한다. In addition, the present invention provides a kiwifruit which is effective for improvement of bowel activity produced by the above-mentioned production method.

본 발명에 의하면 식이섬유가 풍부한 참다래를 이용하여 배변활동개선에 효과가 있고, 쉽고 편하게 먹을 수 있는 환을 제조할 수 있게 된다. According to the present invention, it is possible to produce a ring which is effective in improving bowel movement and which can be eaten easily and easily, by using a dietary fiber-rich quail.

도 1은 본 발명에 따른 배변활동개선에 효과가 있는 참다래환 제조방법의 개념도이다.
도 2는 변의 중량 및 수분함량을 비교하여 나타낸 도이다.
도 3은 건조한 변을 각 군별로 나타낸 도이다.
도 4는 해부한 소화관 및 활성탄 최선단부를 각 군별로 나타낸 도이다.
도 5는 소화관 이동률을 비교하여 나타낸 도이다.
FIG. 1 is a conceptual diagram of a method for manufacturing a quail pear ring, which is effective for improving bowel movement according to the present invention.
Fig. 2 is a diagram showing the comparison of the weight and the moisture content of the sides. Fig.
Fig. 3 is a diagram showing dry sides in each group.
Fig. 4 is a view showing the dissected digestive tract and the best end of activated carbon for each group.
5 is a graph showing the comparison of the digestive tract moving rates.

본 발명의 실시예에 따른 배변활동개선에 효과가 있는 참다래환 제조방법은 도 1과 같다. 도 1을 참조하면 본 실시예의 제조방법은 세척단계(S11)와, 건조단계(S13)와, 볶음단계(S15)와, 분쇄단계(S17)와, 찹쌀죽 제조단계(S19)와, 혼합반죽단계(S21)와, 환 성형단계(S23)와, 환 건조단계(S25)를 포함한다. A method of manufacturing a quince pear ring which is effective in improving bowel activity according to an embodiment of the present invention is shown in Fig. Referring to FIG. 1, the manufacturing method of the present embodiment includes a washing step S11, a drying step S13, a roasting step S15, a pulverizing step S17, a glutinous rice porridge making step S19, A step S21, a ring-forming step S23, and a ring-drying step S25.

세척단계(S11)에서는 참다래, 함초, 대두, 질경이, 무화과를 세척하여 이물질을 제거한다. 건조단계(S13)에서는 세척단계(S11)에서 세척된 참다래와 무화과는 동결건조하고, 함초와 질경이는 냉풍건조한다. 볶음단계(S15)에서는 세척단계(S11)에서 세척된 대두를 볶는다. 분쇄단계(S17)에서는 건조단계(S13)에서 건조된 참다래, 함초, 질경이, 무화과와 볶음단계(S15)에서 볶은 대두를 100~200mesh로 분쇄한다. 찹쌀죽 제조단계(S19)에서는 정제수 1L에 찹쌀 140g를 넣고 끓인다. 혼합반죽단계(S21)에서는 분쇄단계(S17)에서 분쇄된 참다래 분말 1,000g과, 함초 분말 550g과, 볶은 대두 분말 550g과, 질경이 분말 220g과, 무화과 분말 140g과, 유산균(Bacillus velezensis) 0.5g에 찹쌀죽 제조단계(S19)에서 제조된 찹쌀죽 26.4~31.4중량%를 부어 혼합한 후 반죽한다. 환 성형단계(S23)에서는 혼합반죽단계(S21)에서 반죽한 시료 환으로 만든다. 환 건조단계(S25)에서는 환 성형단계(S23)에서 성형된 환을 80℃에서 12시간 건조시킨다. In the cleaning step (S11), the cherry, green tea, soybean, plantain, and fig are washed to remove foreign matter. In the drying step (S13), the chickpea and the fig cleaned in the washing step (S11) are lyophilized, and the green pepper and plantain are cold-air dried. In the roasting step (S15), the washed soybeans are roasted in the washing step (S11). In the pulverizing step (S17), the dried chopped rice straw, green tea, green tea plantain, fig and dried roasted soybean in step (S15) are pulverized to 100 to 200 mesh. In the step of producing glutinous rice porridge (S19), 140 g of glutinous rice is added to 1 L of purified water and boiled. In the mixed kneading step S21, 1,000 g of crushed cherry powder, 550 g of green tea powder, 550 g of roasted soybean powder, 220 g of plantain powder, 140 g of fig powder, and 0.5 g of lactic acid bacteria (Bacillus velezensis) 26.4 to 31.4 wt% of glutinous rice bran prepared in the step of making glutinous rice bran (S19) is poured and kneaded. In the ring-forming step (S23), the kneaded sample is kneaded in the kneading step (S21). In the ring-drying step (S25), the ring formed in the ring-forming step (S23) is dried at 80 DEG C for 12 hours.

본 발명의 실시예에 대한 참다래의 배변활동개선 효과에 대하여 다음과 같이 실험하였다. The effect of improving the bowel movement of the kiwifruit according to the embodiment of the present invention was tested as follows.

본 발명의 실시예인 참다래환의 배변활동개선효과를 확인하기 위해 실험쥐를 이용하여 유효성 평가를 실시하였다. 본 실험에 사용된 실험쥐는 Balb/C 종으로 입수시 주령은 5주령, 체중은 18~22g 으로 식이개시 시 약 9주령이 된다. 입수할 시 외관을 육안적으로 검사한 후 아이케이사이언스(주) 동물사육실에서 순화시키면서 일반증상을 관찰하여 건강한 실험쥐만을 사용하였다. 본 실험은 온도 23±3℃, 상대습도 50±10%, 조명 12시간(08:00 점등 ~ 22:00 소등)로 설정된 동물사육실에서 사육하였다. 사육상자는 스테인레스 제 망사육 상자(280W × 500L ×200H mm)로 순화기간에는 사육상자 당 3마리, 식이 기간에도 사육상자 당 3마리씩 수용하였으며, 실험기간 중 사육상자는 시험번호 및 동물번호를 기입한 사육상자 카드를 붙여 식별하였다. 사료는 실험동물용 고형사료(공급원 : 효창사이언스(주))를 멸균하여 자유 섭취시켰으며, 물은 소독한 상수도수를 자유 섭취시켰다. 사료 및 물은 시험에 영향을 미칠만한 요인이 발견되지 않은 것을 사용하였다. In order to confirm the effect of improving the bowel movements of the zodiac ring, which is an embodiment of the present invention, the efficacy was evaluated using an experimental mouse. The experimental mice used in this experiment are Balb / C species, and their weight is 18 ~ 22g at the age of 5 weeks. At the time of obtaining, the appearance was visually inspected, and general symptoms were observed while refining in the animal breeding room of ICS Science Co., Ltd., and only a healthy experimental mouse was used. The experiment was carried out in an animal breeding room set at a temperature of 23 ± 3 ° C, a relative humidity of 50 ± 10%, and lighting for 12 hours (lights off at 08:00 to 22:00). The breeding box was enclosed by a stainless mesh netting box (280W × 500L × 200H mm). During the refinement period, three animals were kept in each box and three animals were kept in the box during the experiment. One breeding box was identified by attaching a card. The feeds were sterilized by freezing the solid feed for laboratory animals (source: Hyochang Science Co., Ltd.), and the water was freed of the disinfected water. Feed and water were used that did not find any factors that could affect the test.

첫번째 실험은 변의 중량 및 수분량에 관한 실험으로 정상군(대조군)과 실험군(100 Dose, 200 Dose)의 각 5마리씩 군 배정 후 정상군에게는 생리식염수를 실험군에게는 실험식이를 경구투여한다. 실험군에 경구투여하는 실험식이는 제조한 환을 물에 풀어서 실험쥐의 중량 당 투여량을 결정하였다. 실험식이 100 Dose는 100mg/kg으로 실험쥐 몸무게 1kg 당 100mg를 투여한다는 의미이다. 정상군과 실험군 각각에 경구투여 한 후 대사케이지에서 1일 동안 배설되는 대변을 수집하고 수집한 대변의 무게(습중량)를 칭량한 후 건조시킨다. 건조한 대변의 무게(건중량)를 칭량하고 습중량과의 차이(수분함량)를 구하여 분변의 양과 수분량이 정상군과 유의적인 차이가 있는지 확인하였다. The first experiment was to evaluate the weight and moisture content of the stomach. The experimental group was orally administered saline to the normal group and the experimental group to the experimental group after the administration of the test group (control group) and the experimental group (100 Dose, 200 Dose). The experimental diet for oral administration to the experimental group was prepared by dissolving the prepared rings in water to determine the dose per weight of the experimental mice. In the experimental formula, 100 Dose means 100 mg / kg, and 100 mg / kg of the experimental mouse weight. After oral administration to each of the normal group and the experimental group, the stool excreted in the metabolic cage for one day is collected, and the weight (wet weight) of the collected stool is weighed and then dried. The weights of dry feces (dry weight) were weighed and the difference (moisture content) between wet weight and weed weight was determined.

건강기능식품의 기능성시험 가이드라인에 따라 변의 중량과 수분량을 측정함으로써 쾌변에 도움을 주는 식품인지의 여부에 대하여 평가하였다. 변이 비정상적으로 습기가 없으면 전체 질량이 작고, 수분량도 작아지면 대게 변비 증상을 나타낸다. 또한 수분이 너무 많으면 설사라고 표현하고, 전체 질량과 수분량이 매우 증가한다. 도 2는 정상군과 참다래환 100 Dose(100mg/kg) 및 200 Dose(200mg/kg) 식이군에서 변의 중량 및 수분함량을 나타낸 도이다. 변중량(건중량)은 참다래환 100 Dose(100mg/kg) 및 200 Dose(200mg/kg) 식이군에서 정상군과 비교하여 각각 10.5%, 11.4% 높았다. 그리고 수분함량은 정상군과 비교하여 참다래환 100 Dose(100mg/kg) 및 200 Dose(200mg/kg) 식이군에서 23.3% 높은 결과를 얻었다. 도 3은 건조한 변을 각 군별로 나타낸 도이다. The weight and moisture content of the stools were measured according to the functional test guidelines of the functional foods to assess whether they were foods that helped the stool. If the mutation is abnormally wet, the total mass is small, and when the water content is small, it usually shows symptoms of constipation. If too much water is expressed as diarrhea, the total mass and water content increases greatly. FIG. 2 is a chart showing the weight and moisture content of the stool in the normal group and 100 dose (100 mg / kg) and 200 Dose (200 mg / kg) dietary groups. Dietary weights (dry weight) were 10.5% and 11.4% higher in the 100 Dose (100 mg / kg) and 200 Dose (200 mg / kg) diet groups, respectively, than the normal group. The water content was 23.3% higher in the 100 Dose (100 mg / kg) and 200 Dose (200 mg / kg) diet groups than the normal group. Fig. 3 is a diagram showing dry sides in each group.

두번째 실험은 소화관 이동률에 관한 실험으로 정상군(대조군)과 실험군으로 나누고 정상군에게는 생리식염수를 실험군에게는 실험식이를 2주간 경구투여한다. 실험식이는 첫번째 실험과 동일하며 해부 전 실험쥐를 16시간 이상 절식시킨다. 절식한 실험쥐는 10% 활성탄(5% 아라비아 고무현탁액)을 실험쥐용 경구투여기로 0.2ml 투여한다. 투여 30분 후에 실험쥐를 희생시키고, 실험쥐 복부를 정중선을 따라 절개하고 위장과 장이 끊어지지 않도록 유의하여 적출한다. 적출한 소화관은 절개하여 활성탄의 최선단부를 확인한다. 소화관 이동률은 소화관 전체 길이 중 활성탄의 최선단부까지 이동거리로 산출한다. 소화관 이동률의 식은 T(%) = B/A × 100 으로 나타내며, T는 투여한 활성탄의 소화관 이동률이고, A는 소화관 전체의 길이, B는 활성탄의 최선단부까지의 이동거리이다. 도 4는 해부한 소화관 및 활성탄 최선단부를 나타낸 도이며, 도 5는 정상군과 참다래환 100 Dose(100mg/kg) 및 200 Dose(200mg/kg)을 식이한 실험쥐를 해부하여 구한 소화관 이동률을 비교한 도이다. 정상군(대조군)의 소화관 이동률은 평균 64.40%이었다. 참다래환을 식이한 실험쥐의 소화관 이동률은 참다래환 100 Dose(100mg/kg) 식이군이 86.24%, 200 Dose(200mg/kg) 식이군이 89.52% 이었고, 정상군과 비교하여 각각 21.84%, 25.12% 향상되었다. The second experiment is divided into the normal group (control group) and the experimental group, and the physiological saline is administered to the normal group and the experimental group is orally administered to the experimental group for 2 weeks. The experimental diet is the same as the first experiment, and the mice are fasted for at least 16 hours prior to dissection. Fasted rats are dosed with 0.2 ml of 10% activated carbon (5% arabic rubber suspension) in an experimental mouse oral dose. After 30 minutes of administration, the rats are sacrificed and the rat abdomen is incised along the midline and the stomach and intestines are carefully removed to avoid breakage. The extracted digestive tract is incised to identify the best end of activated carbon. The rate of movement of the digestive tract is calculated as the distance traveled to the best end of the activated carbon among the total length of the digestive tract. The expression of the digestive tract migration rate is expressed as T (%) = B / A × 100, where T is the digestive tract migration rate of the administered activated carbon, A is the length of the entire digestive tract and B is the distance traveled to the best end of the activated carbon. FIG. 4 is a graph showing the dissected digestive tract and activated carbon at the best end, and FIG. 5 is a graph showing the digestive tract migration rate obtained by dissecting experimental mice that were fed with 100 Dose (100 mg / kg) and 200 Dose Fig. The average rate of movement of the digestive tract in the normal group (control group) was 64.40%. The rate of gastrointestinal motility in rats fed diets was found to be 86.24% in the 100 Dose (100 mg / kg) diet group and 89.52% in the 200 Dose (200 mg / kg) diet group, which was 21.84% and 25.12% %.

실험결과의 통계적 검정은 SPSS통계 프로그램을 이용하여 수행하였으며, p<0.05 이하일 경우 통계적으로 유의한 것으로 검정하였다. 각 실험군 간의 유의성 검정을 위하여 ANOVA로 분석하였으며 사후검증으로 Ducan's multiple comparison test를 실시하였다. Statistical tests were performed using the SPSS statistical program and statistically significant when p <0.05. For statistical significance, ANOVA was used for the statistical analysis. Ducan's multiple comparison test was used for post test.

Claims (2)

참다래, 함초, 대두, 질경이, 무화과를 세척하는 세척단계와,
상기 세척단계에서 세척된 참다래와 무화과는 동결건조하고, 함초와 질경이는 냉풍건조하는 건조단계와,
상기 세척단계에서 세척된 대두를 볶는 볶음단계와,
상기 건조단계에서 건조된 참다래, 함초, 질경이, 무화과와 상기 볶음단계에서 볶은 대두를 100~200mesh로 분쇄하는 분쇄단계와,
정제수 85~90중량%에 찹쌀 10~15중량%를 넣고 끓이는 찹쌀죽 제조단계와,
상기 분쇄단계에서 분쇄된 참다래 분말 26.4~31.4중량%와, 함초 분말 13.89~17.89중량%와, 볶은 대두 분말 13.89~17.89중량%와, 질경이 분말 4.86~7.86중량%와, 무화과 분말 2.55~5.55중량%와, 유산균(Bacillus velezensis) 0.01~0.02중량%에 상기 찹쌀죽 제조단계에서 제조된 찹쌀죽 26.4~31.4중량%를 부어 혼합한 후 반죽하는 혼합반죽단계와,
상기 혼합반죽단계에서 반죽한 시료를 환으로 만드는 환 성형단계와,
상기 환 성형단계에서 성형된 환을 70~90℃에서 건조시키는 환 건조단계를 포함하는 것을 특징으로 하는 배변활동개선에 효과가 있는 참다래환 제조방법.
A washing step of washing the staple food, the kiwi, the green tea, the soybean, the plantain,
Drying the cherry and the fig cleaned in the washing step by lyophilization, drying the green tea and plantain by cold air drying,
Frying the washed soybeans in the washing step,
A crushing step of crushing the dried chinese cabbage, green tea, plantain, fig and dried roasted soybean in 100 to 200 mesh,
A glutinous rice porridge preparation step in which 10 to 15% by weight of glutinous rice is added to 85 to 90% by weight of purified water,
Wherein the pulverized powder comprises 26.4 to 31.4% by weight of powdered quinceae, 13.89 to 17.89% by weight of green tea powder, 13.89 to 17.89% by weight of roasted soybean powder, 4.86 to 7.86% by weight of plantain powder, 2.55 to 5.55% And mixing and kneading 26.4 to 31.4% by weight of glutinous rice bran prepared in the step of preparing glutinous rice bran with 0.01 to 0.02% by weight of lactic acid bacteria (Bacillus velezensis)
A ring-forming step of kneading the kneaded sample in the mixing and kneading step,
And a ring-drying step of drying the ring formed at the ring-forming step at 70 to 90 ° C.
제1항에 따른 제조방법에 의해서 제조되는 것을 특징으로 하는 배변활동개선에 효과가 있는 참다래환.Which is effective for improving bowel movement, characterized by being manufactured by the manufacturing method according to claim 1.
KR1020140018264A 2014-01-22 2014-02-18 A pill indicating bowel cativity effect and the manufacturing method of it KR101716774B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020140007756 2014-01-22
KR20140007756 2014-01-22

Publications (2)

Publication Number Publication Date
KR20150087769A KR20150087769A (en) 2015-07-30
KR101716774B1 true KR101716774B1 (en) 2017-03-16

Family

ID=53876895

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020140018264A KR101716774B1 (en) 2014-01-22 2014-02-18 A pill indicating bowel cativity effect and the manufacturing method of it

Country Status (1)

Country Link
KR (1) KR101716774B1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210070713A (en) 2019-12-05 2021-06-15 (주)푸른터 Method of making kiwi fruit power and kiwi fruit prepared by this method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090124633A (en) * 2008-05-30 2009-12-03 고려대학교 산학협력단 Pill of grinded mixture of galic and cheonggukjang with enhanced flavor and constipation and method for preparing the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
김동건 외 6인, '제주산 참다래가 Loperamide로 유도된 변비에 미치는 영향', 2011, 한국자원식물학회지 제24권 제1호, 61-68면.*

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210070713A (en) 2019-12-05 2021-06-15 (주)푸른터 Method of making kiwi fruit power and kiwi fruit prepared by this method

Also Published As

Publication number Publication date
KR20150087769A (en) 2015-07-30

Similar Documents

Publication Publication Date Title
KR102076459B1 (en) Composition containing enzyme treatmented Tenebrio molitor for muscle mass enhancement and restorative rejuvenation of recovering patients or elderly patients
KR101980323B1 (en) A method for producing high-protein foods using edible insects
Park et al. Egg production, egg quality, and cecal microbial populations of layersfed diets supplemented with fermented phytogenic feed additive
JP2017535281A (en) Chicory product with less bitterness
KR101619147B1 (en) Composition for preventing or improving constipation or obesity containing pear dietary fiber
CN102860519A (en) Preparation method for reducing hardness of dietary fiber chewable tablets
CN106723087A (en) A kind of tablet containing kelp dietary fiber and preparation method thereof
US20100143319A1 (en) Kiwifruit compositions
CN103652895A (en) Health-care capsule for alleviating arteriosclerosis
Raj et al. Barley phytochemicals and health promoting benefits: A comprehensive review
KR101716774B1 (en) A pill indicating bowel cativity effect and the manufacturing method of it
KR101472190B1 (en) Composition for preventing, treating or improving constipation comprising plant originated tyndalized lactic acid bacteria, Lactobacillus plantarum PMO08 dead cell as an active ingredient
CN101507509A (en) Bean dregs nutrient flour and preparation method thereof
KR100716757B1 (en) Processed food of melon seeds rich in tocopherol
JP2008184392A (en) Lipid metabolism ameliorator originated from citrus depressa hayata
KR101741701B1 (en) Method for producing fermented powder of white rice and amaranth mixture for improving constipation
Sabouri et al. The oleaster (Elaeagnus angustifolia): A comprehensive review on its composition, ethnobotanical and prebiotic values
CN111418839A (en) Health food for improving intestinal flora and metabolism
KR102085436B1 (en) How to process food raw materials using raw silkworms
JP2009029748A (en) Colon cancer suppressing agent using chinese yam
KR101882229B1 (en) Manufacturing method of baby food having silk protein
RU2353106C2 (en) Food additive of sage-brush leaves (felon herb)
JP2009137913A (en) Lipid metabolism improver
CA2680665A1 (en) Use of a barley bran for reducing visceral fat
JP7464297B2 (en) Intestinal regulator

Legal Events

Date Code Title Description
A201 Request for examination
GRNT Written decision to grant
R401 Registration of restoration