KR101694749B1 - Apparatus for manufacturing soft capsule containing solid formulation as core ingredient - Google Patents

Apparatus for manufacturing soft capsule containing solid formulation as core ingredient Download PDF

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Publication number
KR101694749B1
KR101694749B1 KR1020150117682A KR20150117682A KR101694749B1 KR 101694749 B1 KR101694749 B1 KR 101694749B1 KR 1020150117682 A KR1020150117682 A KR 1020150117682A KR 20150117682 A KR20150117682 A KR 20150117682A KR 101694749 B1 KR101694749 B1 KR 101694749B1
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South Korea
Prior art keywords
tablet
die roll
gelatin
gelatin sheet
feeding
Prior art date
Application number
KR1020150117682A
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Korean (ko)
Inventor
양주환
박금덕
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주식회사 서흥
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Application filed by 주식회사 서흥 filed Critical 주식회사 서흥
Priority to KR1020150117682A priority Critical patent/KR101694749B1/en
Priority to US14/865,194 priority patent/US20170049707A1/en
Priority to EP15188232.1A priority patent/EP3141247A1/en
Priority to JP2015197741A priority patent/JP6280903B2/en
Priority to CN201510648481.1A priority patent/CN106466229A/en
Application granted granted Critical
Publication of KR101694749B1 publication Critical patent/KR101694749B1/en
Priority to US16/557,068 priority patent/US20200022874A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/007—Marking tablets or the like

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to an apparatus for manufacturing a soft capsule containing a solid dosage form as its content including: i) a unit supplying a first gelatin sheet cooled in a first gelatin freezing drum (10) to an upper end of a left side die roll (30) through a first transport roller (12); ii) a unit supplying a second gelatin sheet cooled in a second gelatin freezing drum (20) to an upper end of a right side die roll (40) through a second transport roller (22); iii) a unit transporting and injecting a tablet supplied from a tablet supply shooter (50) to a right side die roll outer circumferential decompression surface (402) through a tablet transport roller (45); and iv) a unit molding a tablet-containing second gelatin sheet obtained by the first gelatin sheet supplied to a left side die roll outer circumferential portion (301) and the tablet supplied to a right side die roll outer circumferential portion (401) being injected into a pocket (404) into the soft capsule in a filling molding portion (403) where the left and right side die rolls come into contact with each other by both gelatin sheet surfaces being subjected to thermal compression and cutting with respect to each other after content solution injection from a central content solution injection pipe (801).

Description

[0001] The present invention relates to an apparatus for manufacturing a soft capsule containing a solid formulation as a content,

The present invention relates to an apparatus for producing a soft capsule containing a solid dosage form as a content. More particularly, the present invention relates to a solid dosage form such as a tablet and an apparatus for producing a soft capsule containing the liquid content liquid as a content.

Generally, a gelatin soft capsule is prepared by dissolving a drug in a liquid form as a core component, sealing it and shaping it with gelatin. In addition, the core component of the gelatin soft capsule can be prepared in the form of a paste, a tablet, as well as a dissolved liquid phase.

In the case of a hydrophilic drug, polyethylene glycol (PEG) 200, 300, 400 or 600, propylene glycol or the like is used as a liquid-phase dissolving agent for dissolving pharmaceuticals, and in the case of a hydrophobic drug, lecithin is usually added to soybean oil as a surfactant have.

However, conventional gelatin soft capsules are difficult to use as sustained-release preparations because liquid core drug, which is easily absorbed in the gastrointestinal tract, rapidly increases the blood concentration.

On the other hand, in the case of sustained-release preparations, they have been developed into tablets or hard capsule formulations by adding sustained-release controlled-release polymers to medicines.

However, in the case of tablets or hard capsule preparations containing sustained-release release-controlling polymers, storage stability and / or pH stability are deteriorated when exposed to various external environments, so that when sustained-release tablets or hard capsules are taken two to three months after preparation It was difficult to show the effect of the slow release.

Recently, PCT International Publication WO-A-2012/17326 'Capsules Containing Solid Formulations in Capsules and Apparatus for Manufacturing the Same' discloses a capsule containing a pellet, a small capsule, a small tablet, a sustained- Soft gel capsules containing shaped formulations.

Also, in the patent document, (a) two spreader boxes; (b) two casting drums; (c) a pair of rotary die having suction means; (d) a liquid filler system; (e) a wedge for heating the gelatin ribbon and feeding the filler; And (f) a two-sided dispenser, said two side dispensers comprising: a hopper having a solid dosage form; a channel guide for transferring the solid dosage form; And a grip protrusion for insertion into the formed soft gel pocket.

Further, in the case of the above-described soft gel capsule manufacturing apparatus, a solid formulation is put on a pair of right and left die rolls and rotated together with a die roll, and the solid formulation is injected and sealed on both sides of the left and right gelatin sheets.

However, in order to prepare the soft gel capsules by injecting the solid dosage form on both sides of the left and right gelatin sheets and sealing the gelatin sheets as disclosed in the above-mentioned patent documents, in order to precisely transfer the solid dosage form along the outer peripheral surface of the left and right die rolls, The gelatin sheet and the solid dosage form had to be prevented from being diverted to the outside of the die roll.

The decompression of the outer peripheral surface of the die roll using the vacuum state causes the gelatin sheet transferred along the outer peripheral surface to stick to the outer peripheral surface of the die roll so that the gelatin sheet is not sewn to the right and left, Resulting in defective production of the resulting soft gel article.

In addition, a large amount of electric power is required for decompression using the vacuum state of the pair of left and right die rolls, which is problematic in cost.

Therefore, the present inventor has developed a soft gel manufacturing apparatus to minimize the phenomenon that the gelatin sheet is adhered to the outer circumferential surface of the die roll due to the reduced pressure on the die roll peripheral surface, and to minimize the defect of the soft gel article.

Conventionally, a solid formulation injected from both the right and left die rolls is injected only into the right die roll, so that only the right die roll, in which the solid formulation is injected, The present inventors have developed a soft gel manufacturing apparatus which can minimize the defects of soft gel articles, thereby completing the present invention.

A problem to be solved by the present invention is that a solid dosage form to be injected in both the right and left die rolls is injected only into the right die roll and thus only the right die roll into which the solid dosage form is injected, It is desired to develop a soft gel manufacturing apparatus that minimizes defects of a soft gel article by allowing a more precise suture to be performed continuously and quantitatively when the sheet is sealed.

The object of the present invention is achieved by a method for producing a gelatinized food product comprising the steps of: i) feeding a first gelatin sheet cooled in a first gelatin freezing drum (10) to an upper end of a left die roll (30) through a first feed roller (12); Ii) a unit for feeding the second gelatin sheet cooled in the second gelatin freezing drum 20 to the upper end of the right die roll 40 through the second feed roller 22; Iii) a unit for feeding the tablet supplied from the tablet supply shoe 50 to the right die roll peripheral depression surface 402 through the tablet delivery roller 45; And iv) a first gelatin sheet supplied to the left die roll peripheral portion 301 and a tablet-containing second gelatin sheet into which the tablet supplied to the right die roll peripheral portion 401 is inserted into the pocket 404, And a unit for injecting the inner liquid from the central part liquid infusion tube (801) in the sealed container forming part (403) to be contacted and then thermocompression-cutting each of the gelatin sheet surfaces to form a soft capsule. And to provide a flexible capsule manufacturing apparatus.

The tablet feeder shoe 50 is fed along the inclined surface of the hole-shaped tablet conveying route 501 and sequentially fed by the tablet feed latch 504 to the tablet feed roller 45, As shown in FIG.

On the other hand, the right die roll peripheral depressurizing surface 402 is formed by depressurizing the outer circumferential surface of the die roll 40 through the generation of a vacuum state inside the die roll 40. In the pocket 404 formed on the second gelatin sheet on the peripheral depressurizing surface, So that it can be embedded.

The wedge segment 80 is adjacent to the left die roll circumferential portion 301 through the wedge segment bonding surface 803 and adjacent to the right die roll circumferential portion 401 via the wedge segment bonding surface 802 so that the gelatin sheet is adjacent The first gelatin sheet and the second gelatin sheet inserted into the pockets 404 are controlled and transferred through the first and second gelatin sheets so that the left and right die rolls are in contact with each other, And the two gelatin sheet surfaces are thermocompression-bonded to each other to form a soft capsule.

The effect of the present invention is to provide a device for producing a soft gel which minimizes the defects of the soft gel articles by enabling continuous and quantitative sieving of the gelatin sheets on both left and right sides. In addition, in the soft gel manufacturing apparatus, the decompression using the vacuum state is performed in only one die roll, thereby reducing the power consumption and thereby reducing the cost.

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is an overall configuration diagram of a soft capsule manufacturing apparatus containing the solid dosage form of the present invention as its contents. Fig.
2 is a detailed view showing a configuration of a soft capsule forming unit in a soft capsule manufacturing apparatus containing the solid dosage form of the present invention as contents.
3 is a plan view showing the shape of a tablet supply shooter for dispensing a solid dosage form of the present invention.
4A is a side view illustrating the shape of a tablet supply shooter for dispensing a solid dosage form of the present invention.
Figure 4b is a schematic diagram illustrating a method of delivering a solid dosage form of the invention through a tablet delivery roller.
5 is a partial detail view showing the shape of the tablet supply shooter for injecting the solid dosage form of the present invention.
6A is a schematic view showing a shape after a soft capsule containing the solid dosage form of the present invention as a content is molded.
6B is a schematic view of a soft capsule containing the solid dosage form of the present invention as its contents.

The present invention is directed to a method of manufacturing a gelatin sheet, comprising the steps of: i) feeding a first gelatin sheet cooled in a first gelatin freezing drum (10) to an upper end of a left die roll (30) through a first feed roller (12); Ii) a unit for feeding the second gelatin sheet cooled in the second gelatin freezing drum 20 to the upper end of the right die roll 40 through the second feed roller 22; Iii) a unit for feeding the tablet supplied from the tablet supply shoe 50 to the right die roll peripheral depression surface 402 through the tablet delivery roller 45; And iv) the first gelatin sheet supplied to the left die roll peripheral portion 301 and the tablet-containing second gelatin sheet into which the tablet supplied to the right die roll peripheral portion 401 are put into the pockets 404, And a unit for injecting the inner liquid from the central part liquid infusion tube (801) in the sealed container forming part (403) to be contacted and then thermocompression-cutting each of the gelatin sheet surfaces to form a soft capsule. And a soft capsule manufacturing apparatus.

BRIEF DESCRIPTION OF THE DRAWINGS The invention will be described more fully hereinafter with reference to the accompanying drawings, in which: FIG.

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is an overall configuration diagram of a soft capsule manufacturing apparatus containing the solid dosage form of the present invention as its contents. Fig.

The soft capsule production apparatus containing the solid dosage form of the present invention as its contents is composed of four partial units. The configuration of each partial unit is as follows.

The first partial unit is a unit for feeding the first gelatin sheet cooled in the first gelatin freezing drum 10 to the upper end of the left die roll 30 through the first feed roller 12; The second part unit is a unit for feeding the second gelatin sheet cooled in the second gelatin freezing drum 20 to the upper end of the right die roll 40 through the second feed roller 22. [ In the first partial unit and the second partial unit, a gelatin sheet is formed and supplied to the top of the left and right die rolls.

The third subunit is a unit for transferring the tablet supplied from the tablet supply shoe 50 to the right die roll peripheral depressurizing surface 402 through the tablet conveying roller 45.

Also, the tablet injected in this unit corresponds to the solid dosage form of the present invention, and means a tablet and all solid dosage forms equivalent thereto. For example, tablets, coated tablets, pellets, microcapsules, sustained release solid, immediate release solid, core-shell solid solid, and the like.

The fourth subunit includes a first gelatin sheet supplied to the left die roll peripheral portion 301 and a tablet-containing second gelatin sheet into which the tablet supplied to the right die roll peripheral portion 401 is inserted into the pocket 404, Is injected from the central part liquid infusion tube (801) in the sealed forming part (403) which contacts each other, and then the both gelatin sheet surfaces are thermocompression cut to form a soft capsule.

At this time, the inner liquid is injected from the inner liquid injection tube 801 in the sealed molding part 403, and then the first gelatin sheet and the second gelatin sheet are thermo-compression-molded to produce a soft capsule containing the solid formulation as the contents.

A feature of the present invention is that a conventional solid dosage form is inserted only in the right die roll in both the right and left die rolls, and thus only the right die roll in which the die roll outer peripheral surface reduced pressure and the solid dosage form are inserted, The more sophisticated suture can be performed continuously and quantitatively.

The present invention also provides a soft capsule containing a solid formulation having uniform shape and weight as its contents by controlling the content of the tablet and the content liquid in the soft capsule containing the solid formulation as the content.

2 is a detailed view showing a configuration of a soft capsule forming unit in a soft capsule manufacturing apparatus containing the solid dosage form of the present invention as contents.

2, the wedge segment 80 is adjacent to the left die roll circumferential portion 301 via the wedge segment bonding surface 803 and adjacent to the right die roll circumferential portion 401 via the wedge segment bonding surface 802 The first gelatin sheet and the tablet-containing second gelatin sheet put into the pockets 404 are adjusted and transferred through the adjacent surfaces of the gelatin sheet to form the middle portion content liquid 403 in the sealed forming portion 403 in which the left and right die rolls are in contact with each other, After the contents liquid is injected from the injection tube 801, both sides of the gelatin sheet are thermocompression-cut to form a soft capsule.

At this time, the tablet supplied from the tablet feeder shoe 50 and fed and fed from the tablet feed roller 45 is transported and sealed along the right die roll peripheral depressurizing surface 402 at the upper portion of the right die roll peripheral portion 401, 403), the contents liquid is dropped onto a gelatin sheet supplied with the tablet through a liquid-containing liquid injection tube (801), and is sealed to form a soft capsule containing the solid formulation as the contents.

On the other hand, the right die roll peripheral depressurizing surface 402 is formed by depressurizing the outer circumferential surface of the die roll 40 through the generation of a vacuum state inside the die roll 40, and a conveying tablet is formed in the pocket 404 formed on the second gelatin sheet on the outer peripheral depressurizing surface .

In order to reduce the pressure of the right die roll peripheral depressurizing surface 402, a depressurized vacuum device is connected to the outside of the die roll so that the depressurization of the peripheral surface through the generation of the vacuum state is performed at the corresponding portion inside the right die roll peripheral depressurizing surface 402.

The production of only the right die roll peripheral depressurizing surface 402, which is a feature of the present invention, not only achieves a reduction in cost due to a reduction in power consumption, but also a reduction in cost due to the pressure reduction of the peripheral surface of the die roll The present invention provides a soft capsule containing a predetermined amount of a solid dosage form as a content by minimizing the phenomenon that the gelatin sheet adheres to the outer circumferential surface of the die roll and minimizing product nonuniformity.

3 is a plan view showing the shape of a tablet supply shooter for dispensing a solid dosage form of the present invention.

As shown in FIG. 3, the tablet supply shooter 50 is configured such that the input tablet 503 to be injected is conveyed along the inclined surface of the hole-shaped tablet conveying route 501 and the tablets are sequentially conveyed one by one by the tablet supply latch 504 To the roller (45).

4A is a side view illustrating the shape of a tablet supply shooter for dispensing a solid dosage form of the present invention.

Fig. 4A shows a shape in which the closing tablet 503 in the tablet supplying shoe 50 is conveyed along the inclined surface of the hole-shaped tablet conveying route 501. Fig.

Figure 4b is a schematic diagram illustrating a method of delivering a solid dosage form of the invention through a tablet delivery roller.

The tablet supplied from the tablet supply shoe 50 is conveyed to the right die roll peripheral depressurizing surface 402 via the tablet conveying roller 45. At this time, a method of conveying the tablet of the tablet conveying roller 45 is shown.

The tablet is supplied from the outer circumferential surface of the rotating conveying roller 45, is inserted into the outer circumferential surface of the conveying roller, and then ejected to the right outer circumferential pressure reducing surface 402.

5 is a partial detail view showing the shape of the tablet supply shooter for injecting the solid dosage form of the present invention.

The input tablet 503 in the tablet supply shoe 50 is conveyed along the inclined surface of the hole-shaped tablet conveying route 501 and conveyed and fed to the tablet conveying roller 45 one by one by the tablet supply latch 504 Respectively.

6A is a schematic view showing a shape after a soft capsule containing the solid dosage form of the present invention as a content is molded.

The soft capsule containing the solid formulation of the present invention, which is molded and molded in the envelope forming section 403, contains the contents in the form of a plurality of soft capsules in a left-right and up-down symmetrical shape.

This is different from the case where a plurality of molded soft capsules are asymmetric in the case of a conventional soft capsule packaging apparatus. For example, in the case of the soft capsule formed in the Korean Patent Registration No. 10-1268491 'capsule packing apparatus', the asymmetrical shape of the upper, lower, left and right can be seen in a zigzag shape.

6B is a schematic view of a soft capsule containing the solid dosage form of the present invention as its contents.

As shown in FIG. 6B, the soft capsule containing the solid dosage form of the present invention includes a solid dosage form 201 such as a tablet and a contents liquid 202 inside the gelatin shell 203.

The content liquid is liquid and usually consists of a clear liquid or suspension.

10: first gelatin freezing drum 11: first gelatin spreader box
12: first feed roller 20: second gelatin freezing drum
21: second gelatin spreader box 22: second conveying roller
30: Left die roll 40: Right die roll
45: Tablet feed roller 50: Tablet feeder shoe
51: Tablet supply hopper 60: Contents solution heating hopper
70: System controller 71: Display panel
80: Wedge segment
100: main motor 110: main speed reducer
200: molded solid tablet-containing capsule 201: solid dosage form
202: Content solution 203: Gelatin shell
301: Left die roll peripheral part 310: Guide roller
401: Right die roll peripheral part 402: Die roll peripheral pressure reducing surface
403: sealed molding part 404: pocket
410: Guide roller 451: Transfer tablet
501: Tablet feed route 502: Tablet feed hopper connection
503: input tablet 504: tablet feed latch
505: Tablet supply shoe support 801: Central part liquid infusion tube
802: Wedge segment bonding surface 803: Wedge segment bonding surface
804: side portion liquid infusion tube 805: side portion liquid infusion tube

Claims (4)

I) a unit for feeding a first gelatin sheet cooled in the first gelatin freezing drum 10 to the upper end of the left die roll 30 through a first feeding roller 12;
Ii) a unit for feeding the second gelatin sheet cooled in the second gelatin freezing drum 20 to the upper end of the right die roll 40 through the second feed roller 22;
Iii) a unit for feeding the tablet supplied from the tablet supply shoe 50 to the right die roll peripheral depression surface 402 through the tablet delivery roller 45; And
Iv) The first gelatin sheet supplied to the left die roll peripheral portion 301 and the tablet supplied to the right die roll peripheral portion 401 are adjusted and transferred to the tablet-containing second gelatin sheet put into the pockets 404, A unit for injecting the inner liquid from the inner liquid injection tube 801 at the center of the wedge segment 80 and forming the soft capsules by thermocompression cutting both gelatin sheet surfaces with each other;
The present invention relates to an apparatus for producing a soft capsule,
The tablet supplying shoe 50 is fed along the inclined surface of the hole-shaped tablet feeding route 501 and fed to the tablet feeding roller 45 one by one by the tablet feeding latch 504 ≪ / RTI &
Characterized in that the pockets (404) are formed for incorporating the tablet into the second gelatin sheet on the right die roll peripheral depressurizing surface (402) whose peripheral surface is reduced through the creation of a vacuum inside the right die roll (40) Capsule manufacturing device. delete delete delete
KR1020150117682A 2015-08-21 2015-08-21 Apparatus for manufacturing soft capsule containing solid formulation as core ingredient KR101694749B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
KR1020150117682A KR101694749B1 (en) 2015-08-21 2015-08-21 Apparatus for manufacturing soft capsule containing solid formulation as core ingredient
US14/865,194 US20170049707A1 (en) 2015-08-21 2015-09-25 Manufacturing method for softgel capsule containing solid and liquid formulations as core ingredient
EP15188232.1A EP3141247A1 (en) 2015-08-21 2015-10-02 Manufacturing method for softgel capsule containing solid and liquid formulations as core ingredient
JP2015197741A JP6280903B2 (en) 2015-08-21 2015-10-05 Method for producing soft gel capsule containing solid preparation and liquid preparation as core component
CN201510648481.1A CN106466229A (en) 2015-08-21 2015-10-09 Containing solid preparation and liquid preparation as the soft capsule of nucleuses manufacture method
US16/557,068 US20200022874A1 (en) 2015-08-21 2019-08-30 Manufacturing method for softgel capsule containing solid and liquid formulations as core ingredient

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020150117682A KR101694749B1 (en) 2015-08-21 2015-08-21 Apparatus for manufacturing soft capsule containing solid formulation as core ingredient

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107791138A (en) * 2017-11-03 2018-03-13 孙利成 Process equipment for pharmacy
CN107856239A (en) * 2017-10-25 2018-03-30 浙江华光胶囊股份有限公司 Capsule production system
KR102140013B1 (en) 2019-03-25 2020-09-02 유엠에스엔지니어링 주식회사 Capsule manufacturing apparatus
KR102140014B1 (en) 2019-03-25 2020-09-02 유엠에스엔지니어링 주식회사 Capsule manufacturing apparatus

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567714A (en) * 1980-11-24 1986-02-04 Chasman Sydney A Method and apparatus for forming capsules
JPS61109566A (en) * 1984-10-31 1986-05-28 アリメント工業株式会社 Production of soft capsule enveloping solid component
KR200315638Y1 (en) * 2003-03-10 2003-06-09 심동빈 Cooling device for cooling drum of the machine for manufacturing soft gelatin capsule
JP2004283092A (en) * 2003-03-24 2004-10-14 Sankyo:Kk Gummy and method for producing the same and apparatus therefor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567714A (en) * 1980-11-24 1986-02-04 Chasman Sydney A Method and apparatus for forming capsules
JPS61109566A (en) * 1984-10-31 1986-05-28 アリメント工業株式会社 Production of soft capsule enveloping solid component
KR200315638Y1 (en) * 2003-03-10 2003-06-09 심동빈 Cooling device for cooling drum of the machine for manufacturing soft gelatin capsule
JP2004283092A (en) * 2003-03-24 2004-10-14 Sankyo:Kk Gummy and method for producing the same and apparatus therefor

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107856239A (en) * 2017-10-25 2018-03-30 浙江华光胶囊股份有限公司 Capsule production system
CN107856239B (en) * 2017-10-25 2020-08-18 浙江华光胶囊股份有限公司 Capsule production device
CN107791138A (en) * 2017-11-03 2018-03-13 孙利成 Process equipment for pharmacy
KR102140013B1 (en) 2019-03-25 2020-09-02 유엠에스엔지니어링 주식회사 Capsule manufacturing apparatus
KR102140014B1 (en) 2019-03-25 2020-09-02 유엠에스엔지니어링 주식회사 Capsule manufacturing apparatus

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