KR101685958B1 - Root canal filler and method for preparing the same - Google Patents

Abstract

The present invention relates to a body inserted into a root canal; And a modified layer formed on the surface of the body, wherein the modified layer is a dental root canal filler comprising gutta percha. The dental root canal filling material of the present invention can improve the bonding force between the root canal filling material and the sealer by coating the gutta teas solution, and when used for root canal treatment, the prognosis is good and the success rate of the root canal treatment can be improved.

Description

FIELD OF THE INVENTION [0001] The present invention relates to a dental root canal filling material,

TECHNICAL FIELD The present invention relates to a dental root canal filling material, and more particularly, to a dental root canal filling material capable of improving the bonding strength between a root canal filling material and a sealer by coating a gutta-percha solution, and a method for producing the same.

Ideal dental root canal fillers can be used for biocompatibility, bactericidal properties, sealing properties, stability, workability, easily placed and distributed properties, hardening time, enhance tooth structure, homogeneity, and radio opacity.

Conventional materials used for dental root canal fillings are gutta percha and sealer. Root canal treatment with gerontar tea and sealer is called the orthograde canal filling technique. There are usually two ways. First, the cone (B, C, D) corresponding to the body of the filler is inserted into the root canal by lateral pressure method, which is one of the orthograde canal filling methods. And the root canals are filled. The empty space between the charged tipper car cone and the root canal is filled with a sealer. Vertical pressurization, another method of orthograde canal filling, was performed by inserting a detent car cone into the root canal and pressing the detent car cone vertically using a tool called a plugger Fill the root canal filling material in the root canal.

There is a fundamental problem in that, when performing the procedure using the gerotor car, there is almost no initial hermeticity of the apical portion, and the gerotor car is absorbed in the living body and the airtightness can not be maintained in the long term. Most of the sealers are cytotoxic in the initial curing stage, and the initial hermeticity such as bubbles in the root canal space is also bad. In addition, orthograde canal filling materials for conservative root canal treatment should be able to completely seal the vicinity of the neural tube 5 mm in the root apical region, that is, 5 mm of the root apical root canal, The filling method is insufficient to acquire a closure effect to determine the success of the root canal treatment clinically.

Korean Patent Laid-Open No. 10-2012-0057136 discloses a dental root canal filling material to which a plasticizer for increasing thermoplasticity is added to a base. The curing time of the dental root canal filling material can be prolonged and advantageous for securing the healing time of the therapist. However, there is a problem that the space inside the root canal can not be completely sealed.

The reason why the space inside the root canal should be completely sealed when treating the root canal is that the space inside the root canal becomes a pathway of bacteria and endotoxin to make the prognosis after the treatment uncertain, It causes the failure of treatment. However, the existing root canal filling material and method have a problem that it is difficult to completely seal the inside of the root canal, and the bonding force between the car tooth car cone and the sealer is weak, so that the empty space between the car tooth car cone and the root canal can not be effectively charged.

It is an object of the present invention to provide a dental root canal filling material capable of improving the bonding force between a root canal filler and a sealer by coating a gerotor tea solution.

It is also an object of the present invention to provide a dental root canal filling material capable of effectively filling a space inside the root canal and improving the success rate of the root canal treatment with good prognosis when used for root canal treatment.

According to an aspect of the present invention,

A body inserted into the root canal; And a modified layer formed on the surface of the body, wherein the modified layer is provided with a dental root canal filler comprising gutta percha.

Wherein the modified layer is selected from the group consisting of zinc oxide, calcium oxide, calcium hydroxide, calcium carbonate, calcium silicate, calcium phosphate, hydroxyapatite, calcium sulfate, aluminum silicate, bioglass, epoxy compound, MTA (Mineral Trioxide Aggregates) , And the like.

Said body comprising 100 parts by weight of rubber; 150 to 420 parts by weight of a filler; And 1 to 25 parts by weight of a plasticizer.

Wherein the rubber is selected from the group consisting of trans-1,4-polyisoprene, cis-1,4-polyisoprene, polybutadiene, styrene-butadiene-styrene (SBS) block copolymers, styrene-isoprene- styrene (SIS) A styrene-butadiene-styrene (SEBS) block copolymer, a styrene-butadiene (SB) block copolymer, and a polyurethane.

The filler may be zinc oxide.

The filler may further include at least one selected from zirconium oxide, calcium silicate, calcium phosphate, calcium hydroxide, calcium sulfate, hydroxyapatite, calcium carbonate, calcium aluminate and hydroxyapatite.

Wherein the plasticizer is one selected from the group consisting of paraffin wax, microcrystalline wax, ceresin wax, Carnauba wax, polyester wax, polyolefin wax, bee wax, Or more.

The body may further comprise a contrast agent.

The contrast agent may include at least one selected from barium oxide, barium sulfate, zirconium oxide, tantalum oxide, yttrium oxide and calcium tungstate.

And a cone shape in which the diameter increases from one end of the body inserted into the root canal to the other end toward the other end.

According to another aspect of the present invention,

A body inserted into the root canal; A modified layer formed on the surface of the body; And a sealer formed on the surface of the modified layer, wherein the modified layer comprises a gutta percha.

Wherein the sealer is selected from the group consisting of zinc oxide, calcium oxide, calcium hydroxide, calcium carbonate, calcium silicate, calcium phosphate, hydroxyapatite, calcium sulfate, aluminum silicate, bioglass, epoxy compound, MTA (Mineral Trioxide Aggregates) And may include at least one selected.

The reforming layer may include some or all of the components of the sealer.

According to another aspect of the present invention,

Dissolving the gutta-percha in a solvent to prepare a coating solution containing gutta-percha (step a); Coating the coating solution on the surface of the body inserted into the root canal to prepare a surface modified body (step b); And drying the surface-modified body to produce a dental root canal filler (step c).

After Step (a), a metal compound selected from the group consisting of zinc oxide, calcium oxide, calcium hydroxide, calcium carbonate, calcium silicate, calcium phosphate, hydroxyapatite, calcium sulfate, aluminum silicate, bioglass, epoxy compound, MTA (Mineral Trioxide Aggregates) (Step a ') to prepare a coating solution containing a gutta-percha and an additive.

Wherein the solvent is selected from the group consisting of tetrahydrofuran, benzene, fluorobenzene, toluene, trifluorotoluene, xylene, cyclohexane, 2-methyltetrahydrofuran, cyclodextran, ethanol, isopropyl alcohol, dimethyl carbonate, , Diethyl carbonate, methyl propyl carbonate, methyl propionate, ethyl propionate, methyl acetate, ethyl acetate, propyl acetate, dimethoxyethane, 1,3-dioxolane, diglyme, tetraglyme, ethylene carbonate, propylene Carbonate, y-butyrolactone, and sulfolane.

In step a ', the additive may be included in an amount of 1 to 20 wt% based on the total weight of the coating solution containing the detergent and the additive.

According to another aspect of the present invention,

Preparing a composite of a sealer and a dental root canal filler by attaching a sealer to the one end of the dental root canal filler (step 1); And inserting a composite of the sealer and the dental canal filler into the root canal (step 2); And filling the sealer in a space between the root canal and the dental canal filling material (step 3).

Step 3 may be to fill the sealer using a spreader or plugger.

The dental root canal filling material of the present invention has an effect of improving the bonding force between the root canal filling material and the sealer by coating the gutta-percha solution unlike the prior art.

In addition, the space inside the root canal can be effectively filled, and when the dental root canal filling material of the present invention is used for root canal treatment, the prognosis is good and the root canal success rate can be improved.

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 is a schematic representation of a structure of a dental canal filler assembly of the present invention and a cross-sectional view (A-A ') wherein the dental canal filler assembly is inserted into a root canal.
2 is a flow chart illustrating a method for manufacturing a dental root canal filler of the present invention.
FIG. 3 is a SEM photograph of a specimen prepared by coating a dental root canal filler of the present invention with a sealer and curing for a certain period of time at a magnification of 1,000 times. FIG.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings so that those skilled in the art can easily carry out the present invention.

However, the following description does not limit the present invention to specific embodiments. In the following description of the present invention, detailed description of related arts will be omitted if it is determined that the gist of the present invention may be blurred .

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The singular expressions include plural expressions unless the context clearly dictates otherwise. In the present application, the terms "comprises ",or" having ", and the like, specify that the presence of stated features, integers, steps, operations, elements, or combinations thereof, But do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, or combinations thereof.

Hereinafter, the dental root canal filling material of the present invention will be described in detail.

The dental root canal filling material of the present invention includes a body inserted into the root canal and a modified layer formed on the surface of the body, and the modified layer may include a gutta percha.

Wherein the modifying layer is selected from the group consisting of zinc oxide, calcium oxide, calcium hydroxide, calcium carbonate, calcium silicate, calcium phosphate, hydroxyapatite, calcium sulfate, aluminum silicate, bioglass, epoxy compound, MTA (Mineral Trioxide Aggregates) And the like.

The body may comprise 100 parts by weight of rubber, 150 to 420 parts by weight of filler and 1 to 25 parts by weight of plasticizer.

The rubber may be selected from the group consisting of trans-1,4-polyisoprene, cis-1,4-polyisoprene, polybutadiene, styrene-butadiene-styrene (SBS) block copolymers, styrene-isoprene- Styrene-ethylene-butadiene-styrene (SEBS) block copolymer, styrene-butadiene (SB) block copolymer and polyurethane.

The filler may strengthen the elasticity and tensile force of the body, and may preferably include zinc oxide. The filler may be selected from the group consisting of zirconium oxide, calcium silicate, calcium phosphate, calcium hydroxide, calcium sulfate, hydroxyapatite, calcium carbonate, calcium aluminate, And the like.

The plasticizer may be paraffin wax, microcrystalline wax, ceresin wax, Carnauba wax, polyester wax, polyolefin wax, bee wax, liquid paraffin, etc. .

In addition, the body may further include a contrast agent, but the present invention is not limited thereto. The dental root canal filling material can fill the root canal even if there is no contrast agent in the body. However, the contrast agent increases the contrast of the image by artificially increasing the X-ray absorption difference of each tissue so that the tissue or blood vessels can be seen well during the radiological examination. This makes it possible to distinguish the living body structure or the lesion from the surroundings It may be desirable to include the dental root canal filler as it improves the diagnostic value of the dental root canal filler. The contrast agent may be barium oxide, barium sulfate, zirconium oxide, tantalum oxide, yttrium oxide, calcium tungstate, or the like.

The body may be in the form of a cone having a larger diameter from one end of the tooth root canal to the other end thereof.

BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 is a schematic representation of a structure of a dental canal filler assembly of the present invention and a cross-sectional view (A-A ') wherein the dental canal filler assembly is inserted into a root canal.

Hereinafter, the dental root canal filling material assembly of the present invention will be described in detail with reference to Fig.

The dental canal filling material assembly 300 of the present invention includes a body 110 inserted into a root canal, a modified layer 120 formed on the surface of the body 110, and a sealer 120 formed on the surface of the modified layer 120 200, and the reforming layer 120 includes a gutta percha.

The sealer 200 may be formed of a material selected from the group consisting of zinc oxide, calcium oxide, calcium hydroxide, calcium carbonate, calcium silicate, calcium phosphate, hydroxyapatite, calcium sulfate, aluminum silicate, bioglass, epoxy compound, MTA (Mineral Trioxide Aggregates) Silicon dioxide, and the like. The reforming layer 120 may include some or all of the components of the sealer 200 to improve the bonding force between the dental root tube filler 100 and the sealer 200. Therefore, the dental root canal filling material assembly 300 can effectively fill and seal the space inside the root canal without creating any gap between the dental root canal filling material 100 and the sealer 200.

2 is a flow chart illustrating a method for manufacturing a dental root canal filler of the present invention.

Hereinafter, a method for manufacturing a dental root canal filling material of the present invention will be described in detail with reference to FIG.

First, the gutta-percha is dissolved in a solvent to prepare a coating solution containing gutta-percha (step a).

The solvent may be selected from the group consisting of tetrahydrofuran, benzene, fluorobenzene, toluene, trifluorotoluene, xylene, cyclohexane, 2-methyltetrahydrofuran, cyclodextrin, ethanol, isopropyl alcohol, dimethyl carbonate, ethyl methyl carbonate , Diethyl carbonate, methyl propyl carbonate, methyl propionate, ethyl propionate, methyl acetate, ethyl acetate, propyl acetate, dimethoxyethane, 1,3-dioxolane, diglyme, tetraglyme, ethylene carbonate, propylene Carbonate,? -Butyrolactone, sulfolane, and the like.

Step a can be carried out at 20 캜 to 60 캜, preferably at 25 캜 to 55 캜, more preferably at 30 캜 to 50 캜.

After step (a), after step (a), zinc oxide, calcium oxide, calcium hydroxide, calcium carbonate, calcium silicate, calcium phosphate, hydroxyapatite, calcium sulfate, aluminum silicate, bioglass, epoxy compound, mineral trioxide (MTA) (Step a ') to prepare a coating solution containing a giant deterrent and an additive. In this case, the additive may be contained in an amount of 1 to 20 wt%, preferably 1 to 18 wt%, more preferably 1 to 15 wt% based on the total weight of the coating solution containing the detergent and the additive .

Step a 'can be carried out at 20 ° C to 60 ° C, preferably at 25 ° C to 55 ° C, more preferably at 30 ° C to 50 ° C.

Next, the surface of the body inserted into the root canal is coated with the coating solution to prepare a surface-modified body (step b).

During the coating, it may be preferable to coat the coating solution while stirring to prevent the coating solution from aggregating.

Step b may be carried out at 20 캜 to 60 캜, preferably at 25 캜 to 55 캜, more preferably at 30 캜 to 50 캜. However, the execution temperature of step b is not limited to this and may vary depending on the thickness of the body.

Finally, the surface modified body is dried to produce a dental canal filler (step c).

The drying may be carried out at 10 to 50 캜, preferably at 15 to 40 캜, more preferably at 20 to 30 캜, and most preferably at room temperature. However, the temperature at which the step c is performed is not limited thereto and may vary depending on the thickness of the body. If the thickness of the body is thin, it may be rapidly dried in hot air at 40 to 50 DEG C after being cured in water at room temperature to promote curing.

In addition, the drying can be performed for 10 minutes to 60 minutes, preferably 10 minutes to 40 minutes, more preferably 10 minutes to 30 minutes. However, the drying time may vary depending on the drying temperature.

Hereinafter, the tooth root canal filling method of the present invention will be described in detail.

First, a sealer is embedded in the one end of the dental root canal filling material to prepare a composite of a sealer and a dental root canal filling material (step 1).

Next, a composite of the sealer and the dental canal filler is inserted into the root canal (Step 2).

Finally, the sealer is filled in the space between the root canal and the dental canal filler (step 3).

Step 3 can fill the sealer using a spreader or a plugger. A pressure can be applied to the spreader or the plunger. A spreader can be used when pressure is applied to the dental canal filling material sideways, and a plugger can be used when pressure is applied perpendicularly to the dental canal filling material. However, the present invention is not limited thereto, and any mechanism capable of charging the sealer can be used.

As described above, since the sealer may include some or all of the components of the modified layer, the bonding force between the dental root tube filler and the sealer can be improved. Therefore, the dental root canal filling material and the sealer can effectively fill and seal the space inside the root canal.

[Example]

Hereinafter, preferred embodiments of the present invention will be described. However, this is for illustrative purposes only, and thus the scope of the present invention is not limited thereto.

Production Example 1: Production of a body

100 parts by weight of trans-1,4-polyisoprene was stirred at 80 占 폚 for 25 minutes. Then, 100.5 parts by weight of zinc oxide was added and stirred at 77.6 ° C for 10 minutes. Then, 176.92 parts by weight of zirconium oxide was added and stirred at 80 DEG C for 20 minutes. Then, 50 parts by weight of barium sulfate was added thereto, and the mixture was stirred at 84.4 占 폚 for 10 minutes. Finally, 4.11 parts by weight of liquid paraffin CARNATION White Mineral Oil was added and stirred at 75 DEG C for 10 minutes to prepare a body sheet. The body sheet was rolled to a predetermined thickness and then cut in the transverse direction to prepare a body pellet. The body pellet was rolled into a needle-shaped body having a thin tip and a larger diameter toward the opposite side of the head. This type of manufacturing method is disclosed in Korean Patent Registration No. 0123461.

Production Example 2: Preparation of a bio-paste

Nano-sized calcium silicate was prepared, and 25 parts by weight of calcium silicate and 100 parts by weight of trans-1,4-polyisoprene were mixed to prepare a bio-paste.

Example 1: Preparation of dental canal filling material

10 g of trans-1,4-polyisoprene was added to 1 L of tetrahydrofuran and stirred at 40 ° C for 12 hours to prepare a gutta-percha coating solution. 20 g of the bio-paste prepared according to Preparation Example 2 was added to 400 ml of the above-mentioned tapper tea coating solution and stirred at 40 ° C. The coating solution was coated on the body manufactured according to Preparation Example 1 with stirring at 40 캜 so that the bio-paste did not aggregate, thereby modifying the surface. The surface-modified body was dried at room temperature for 1 hour to prepare a dental root canal filling material.

Comparative Example 1: Preparation of Conventional Dental Root Canal Fillers

A conventional dental root canal filling material was prepared in the same manner as in Preparation Example 1.

[Test Example]

Test Example 1: Confirmation of Bonding Force between Dental Root Canal Filler and Sealer

The interface between the dental root canal filling material prepared according to Example 1 and the sealer was measured by SEM and the results are shown in Fig.

Referring to FIG. 3, a dental root canal filling material was coated with a sealer and cured for a predetermined time to prepare a test piece. The cross section of the specimen was measured at a magnification of 1,000 times, and it was confirmed that there was no gap between the dental canal filler and the sealer.

Therefore, it was confirmed that the dental root canal filling material of the present invention and the sealer have excellent bonding strength.

Test Example 2: Measurement of Fracture Resistance of Dental Root Canal Fillers

The fracture resistance of dental root canal fillers and teeth prepared according to Example 1 and Comparative Example 1 was measured. The dental root canal filler prepared according to Example 1 and Comparative Example 1 was coated with a sealer and cured to prepare specimens. The specimens and teeth were measured for fracture resistance using a universal testing machine (Z020, Zwick, Germany). A load was applied to the center of the specimen using a metal tool with an end rounded cross section and a vertical load was applied until the specimen was fractured at a crosshead speed of 1 mm / . At this time, the maximum fracture resistance of each specimen was measured.

The dental root canal filling prepared according to Example 1 fractured at a mean force of about 370 N and the teeth fractured at an average force of about 380 N. [ On the other hand, the dental canal filling material prepared according to Comparative Example 1 was fractured at an average force of about 305N.

Therefore, the dental root canal filling material of the present invention has excellent fracture resistance as compared with the conventional dental root canal filling material, and has fracture resistance equivalent to a tooth.

The scope of the present invention is defined by the appended claims rather than the detailed description and all changes or modifications derived from the meaning and scope of the claims and their equivalents are to be construed as being included within the scope of the present invention do.

100: Dental root canal filling material
110: Body
120: reformed layer
200: Sealer
300: Dental root canal filling assembly

Claims (19)

A body inserted into the root canal; And
And a modified layer formed on the surface of the body,
Wherein the modifying layer is a dental root canal filler comprising gutta percha,
Wherein the modifying layer is at least one selected from the group consisting of zinc oxide, calcium oxide, calcium hydroxide, calcium carbonate, calcium silicate, calcium phosphate, hydroxyapatite, calcium sulfate, aluminum silicate, bioglass, epoxy compound, MTA (Mineral Trioxide Aggregates) Wherein the root canal filling material comprises at least one selected from the group consisting of: delete The method according to claim 1,
The body
100 parts by weight of rubber;
150 to 420 parts by weight of a filler; And
1 to 25 parts by weight of a plasticizer;
Dental root canal filling material. The method of claim 3,
Wherein the rubber is selected from the group consisting of trans-1,4-polyisoprene, cis-1,4-polyisoprene, polybutadiene, styrene-butadiene-styrene (SBS) block copolymers, styrene-isoprene- styrene (SIS) A styrene-butadiene-styrene (SEBS) block copolymer, a styrene-butadiene (SB) block copolymer, and a polyurethane. The method of claim 3,
Wherein the filler is zinc oxide. 6. The method of claim 5,
Wherein the filler further comprises at least one selected from zirconium oxide, calcium silicate, calcium phosphate, calcium hydroxide, calcium sulfate, hydroxyapatite, calcium carbonate, calcium aluminate and hydroxyapatite. The method of claim 3,
Wherein the plasticizer is one selected from the group consisting of paraffin wax, microcrystalline wax, ceresin wax, Carnauba wax, polyester wax, polyolefin wax, bee wax, Or more of the root canal filling material. The method of claim 3,
Wherein the body further comprises a contrast agent. 9. The method of claim 8,
Wherein the contrast agent comprises at least one selected from barium oxide, barium sulfate, zirconium oxide, tantalum oxide, yttrium oxide and calcium tungstate. The method according to claim 1,
Wherein the body is in the form of a cone having a larger diameter from one end of the body inserted first into the root canal to the opposite end. A body inserted into the root canal;
A modified layer formed on the surface of the body; And
And a sealer formed on the surface of the modified layer
Wherein the reforming layer comprises a gutta percha. 12. The method of claim 11,
Wherein the sealer is selected from the group consisting of zinc oxide, calcium oxide, calcium hydroxide, calcium carbonate, calcium silicate, calcium phosphate, hydroxyapatite, calcium sulfate, aluminum silicate, bioglass, epoxy compound, MTA (Mineral Trioxide Aggregates) Wherein the dental root canal filling material comprises at least one selected from the group consisting of: 12. The method of claim 11,
Wherein the modifying layer comprises some or all of the components of the sealer. ≪ RTI ID = 0.0 > 11. < / RTI > Dissolving the gutta-percha in a solvent to prepare a coating solution containing gutta-percha (step a);
Coating the coating solution on the surface of the body inserted into the root canal to prepare a surface modified body (step b); And
Drying the surface modified body to produce a dental root canal filler (step c);
Wherein the method comprises the steps of: 15. The method of claim 14,
After Step (a), a metal compound selected from the group consisting of zinc oxide, calcium oxide, calcium hydroxide, calcium carbonate, calcium silicate, calcium phosphate, hydroxyapatite, calcium sulfate, aluminum silicate, bioglass, epoxy compound, MTA (Mineral Trioxide Aggregates) Wherein the step (a ') further comprises the step of dissolving at least one selected additive selected from the group consisting of a dentifrice and an additive to prepare a coating solution comprising a gutta-percha and an additive (step a'). 15. The method of claim 14,
Wherein the solvent is selected from the group consisting of tetrahydrofuran, benzene, fluorobenzene, toluene, trifluorotoluene, xylene, cyclohexane, 2-methyltetrahydrofuran, cyclodextran, ethanol, isopropyl alcohol, dimethyl carbonate, ethyl methyl carbonate , Diethyl carbonate, methyl propyl carbonate, methyl propionate, ethyl propionate, methyl acetate, ethyl acetate, propyl acetate, dimethoxyethane, 1,3-dioxolane, diglyme, tetraglyme, ethylene carbonate, propylene Wherein the dental root canal filling material comprises at least one selected from the group consisting of carbonates, gamma -butyrolactone, and sulfolane. 16. The method of claim 15,
Wherein in step a ', the additive is included in an amount of 1 to 20 wt% based on the total weight of the coating solution containing the gerbera tea and the additive. delete delete

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