KR101465355B1 - Intraoperative Neurophysiologic Monitoring System - Google Patents

Abstract

The purpose of the present invention is to prevent restriction of distance due to the length of a wire between a transmitter and a receiver, the wire from blocking views and being obstructive to a surgery, and disconnection of the wire, by installing a wireless transmitter in a transmission part of a bioelectric signal measuring device and providing detachable electrodes. Provided is a bioelectric signal measuring device comprising: an insulation film which can be attached to a circumferential surface of an internal tube inserted into an opening on a human body; multiple thin film electrodes which are arranged to be in contact with a muscle or a nerve where a part of the internal tube is positioned; a transmitter which wirelessly transmits bioelectric signals detected by the thin film electrodes; a conducting wire which electrically connects the thin film electrodes and the transmitter; and a battery which is provided to operate the transmitter, wherein the electrodes, transmitter, conducting wire, and battery are arranged on the insulation film. Also, provided is a bioelectric signal measuring device comprising: an insulation film which consists of a header part with a wide area and a tail part connected to the header part, and which can be attached along the length of an internal tube inserted into a human body; multiple thin film electrodes which are disposed on the header part being the opposite to the insulation film side attached to the internal tube, and arranged to be in contact with a muscle or nerve where a part of the internal tube is positioned; and a conducting wire which is positioned on the tail part of the insulation film, and has one end electrically connected to the thin film electrodes and the other end connected to the end of the tail part.

Description

{Intraoperative Neurophysiologic Monitoring System}

The present invention relates to a wireless bio-electrical signal measuring apparatus capable of measuring a bio-electrical signal in contact with muscles or nerves in a human body. In particular, the present invention relates to an apparatus for measuring a bio- The present invention relates to an apparatus for measuring a bioelectrical signal of a wireless terminal and wirelessly transmitting the same.

Intraoperative Neurophysiologic Monitoring (INM, or IOM) is widely used in neurological surgery to help early detection of damage to the nervous system during surgery, reduce postoperative complications, and safely perform high-risk surgery. During surgery, neurological monitoring is a method of monitoring and monitoring abnormalities of the nervous system during surgery using electrophysiological methods. Electrophysiologic methods include EEG, EMG, and EMG. (Evoked potentials in neurological monitoring during surgery, Seodaewon, Korean Journal of Clinical Neurophysiology, Vol. 9, No. 2, 2007).

In the case of general anesthesia during surgery, the patient becomes unconscious and easily develops airway obstruction or respiratory depression. To prevent this, Endotracheal Tube is used as a method of general airway management in most general anesthesia. An endotracheal tube is a tube that is inserted into the airway for artificial respiration during surgery. The purpose of the endotracheal intubation for inserting the endotracheal tube into the human body is to provide a means of delivering the endotracheal intubation to the human body through low ventilation (state in which the carbon dioxide is not properly discharged through the respiration), hypoxia, (To the respiratory tract).

Korean Patent Publication No. 2012-0087933 relates to an "intracoronary tube device", wherein a bioelectrical signal measuring device integrally attached to the outer circumferential surface of the intracoronary tube is used so that an electrode of the measuring device contacts the patient's vocal cords during surgery, Facilitating bioelectric signal measurement. It is configured to receive an electromyography (EMG) signal from the larygeal muscles when an electrode is installed in the patient's airway. The device not only opens the patient's airway, which is an intrinsic characteristic of the intracranial tube, but also conducts nerve monitoring of the hind paw during the surgical procedure.

However, in the prior art in which the bioelectrical signal measuring device is integrally connected to the intracoronary tube, the surge current is applied to the surface electrode of the bioelectric signal measuring device mounted on the outer circumferential surface of the intracoronary tube, And an external receiver are connected by a wire to record the bioelectric signal. Such prior art outwardly connected wires are limited in their length, so that the distance of use is limited, the wire during operation may obstruct the view of the doctor, may interfere with the operation of the surgical instrument, or may accidentally touch the wire. It may cause danger.

Korea Public Patent 2012-0087933

In order to solve the above problems, the present invention has been made to solve the above problems, and an object of the present invention is to provide a bio-electrical signal measuring apparatus, The present invention is intended to improve the disadvantages of the prior art such as disabling the position of the bioelectric signal display unit by removing the electric wires between the display units receiving and displaying the signals detected by the detection unit,

In order to solve the above problems, the present invention has been accomplished by providing a configuration in which a bioelectrical signal measuring device can be attached to an in-body tube device and includes a radio transmission function.

The present invention relates to an insulating film which can be attached to an outer circumferential surface of an inner tube of a human body inserted in a hole of a human body; A plurality of thin film electrodes arranged so as to contact muscles or nerve parts where one part of the inner body tube is located; A transmitter for wirelessly transmitting the bioelectric signal detected by the thin film electrode; A conductor electrically connecting the thin film electrode and the transmitter; And a battery for operating the transmitter, wherein the electrode, the transmitter, the lead, and the battery are disposed on the insulating film.

The present invention also provides a bioelectrical signal measuring apparatus, wherein the hole of the human body is a trachea.

The present invention also provides an apparatus for measuring bioelectrical signals, wherein the hole of the human body is an anus or a urethra.

The present invention also provides a bioelectrical signal measurement apparatus, wherein the thin film electrodes are plurally printed with a conductive ink.

The present invention also provides a bioelectrical signal measuring device comprising a flexible printed circuit board.

The present invention also provides a bioelectrical signal measuring apparatus, wherein the flexible printed circuit board is made of PET (Polyethylene Telephthalate), PEN (Polyethylene Naphthalate) or PI (Polyimide).

The present invention also provides a bioelectrical signal measuring device, wherein the applied muscle of the measuring device is a hippocampus (including a vocal cord), an anal sphincter, or a urethra sphincter.

The present invention also provides a bioelectrical signal measuring device, wherein the application nerve of the measurement device is the laryngeal nerve (including the back laryngeal nerve) or the genital nerve.

The present invention also provides a bioelectrical signal measuring apparatus, wherein the battery for operating the transmitter is a lithium battery.

The present invention also provides a bioelectrical signal measuring apparatus, further comprising a receiving and displaying unit for receiving and displaying the bioelectrical signal from the transmitter.

The present invention also relates to an insulated film which is composed of a head having a large area and a tail extending to the head, and which can be attached along the length of an in-body tube inserted into the body; A plurality of thin film electrodes arranged at the head portion which is opposite to the surface of the insulating film to be adhered to the human body tube and arranged so as to contact muscles or nerve portions where one portion of the human body inner tube is located; And a lead positioned at a tail portion of the insulating film, one end of which is electrically connected to the thin film electrode and the other end of which leads to an end of the tail portion.

The present invention also provides a bioelectrical signal measurement apparatus, wherein the thin film electrodes are plurally printed with a conductive ink.

The present invention also provides a bioelectrical signal measuring device, wherein the applied muscular part of the measuring device is a hind paw (including a vocal cord), an anal sphincter, or a urethral sphincter.

The present invention also provides a bioelectrical signal measuring device, wherein the application nerve of the measurement device is the laryngeal nerve (including the back laryngeal nerve) or the genital nerve.

The present invention also provides a bioelectrical signal measuring apparatus wherein the lead wire is coated with an electric conductive tape on one side of the tail portion and then coated with insulation.

The present invention also provides a bioelectrical signal measuring apparatus in which the lead wire is printed with conductive ink on one side of the tail portion and then coated with insulation.

The present invention also provides a transfusion apparatus comprising: a transmitter connected to an intracoronary tube projected in vitro without being inserted into a human body; And a receiving and displaying unit for receiving and displaying the bioelectric signal from the transmitter.

The bioelectrical signal measuring apparatus of the present invention transmits the detected bioelectrical signal to the display unit by using the wireless transmission unit so that the bioelectrical signal display unit is out of position due to the electric wire, Of the operating environment.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a reference diagram of an intracoronary tube integrated bioelectrical signal measuring apparatus according to the prior art; FIG.
2 is a conceptual diagram of a bioelectric signal measuring device 1 including a radio transmitter that can be attached to the outer circumferential surface of an endotracheal tube.
3 is a cross-sectional view of a portion connecting A-A 'in FIG.
FIG. 4 is a conceptual diagram of an internal tube with an apparatus 1 for measuring bio-electrical signals of FIG. 2 attached thereto.
5 is a conceptual diagram of a bioelectric signal measurement device 2 that can be attached to the outer circumferential surface of an endotracheal tube.
6 is a cross-sectional view of a portion connecting B-B 'of FIG.
FIG. 7 is a conceptual diagram of an internal tube with an apparatus 2 for measuring bio-electrical signals of FIG. 5 attached thereto.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, a wireless bioelectric signal measuring apparatus of the present invention will be described with reference to the accompanying drawings.

Prior to the detailed description of the present invention, terms and words used in the present specification and claims should not be construed as limited to ordinary or dictionary terms. Therefore, the embodiments described in this specification and the configurations shown in the drawings are merely the most preferred embodiments of the present invention and do not represent all the technical ideas of the present invention. Therefore, It is to be understood that equivalents and modifications are possible.

Here, in the entire drawings for explaining the embodiments of the present application, those having the same functions are denoted by the same reference numerals, and a detailed description thereof will be omitted.

INDUSTRIAL APPLICABILITY The bioelectric signal measuring device of the present invention is applicable to a hole of a human body such as an organ, anus, urethra. The purpose of this study is to investigate the function of the recurrent laryngeal nerve by measuring the posterior musculoskeletal muscle including the vocal cord muscle.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a reference diagram of an intracorporeal integrated bioelectrical signal measuring apparatus according to the prior art; FIG. The internal tube includes a beveled tip 100, a cuff 200, a pilot balloon 400, an inflating tube 500, and a connector 600 do. The beveled tip 100 has an inclination angle to facilitate the insertion of the inner tube into the airway when the intubation tube is inserted into the body. The cuff 200 is attached at one end in the direction of insertion into the human body of the intramural tube. The air bag expands when an appropriate amount of air is injected after intubation, and blocks the space between the outer wall of the intracoronary tube and the mucous membrane of the trachea, thereby preventing the air blown into the respirator from leaking out of the airway, And it plays an important role in preventing complications such as pneumonia. In addition, the pilot balloon 400 is connected to the air bag so that the pressure of the air bag during operation can be checked. If the pressure is too high, ischemia in the airway, airway stomach (phenomenon of airway and esophagus connection) and tracheal stenosis are caused. If the pressure is too low, the endotracheal tube may be detached. The inflating tube 500 connects the air bag and the pilot balloon, and injects air into the air bag through the pilot balloon from the outside. The connector 600 is connected to a ventilator.

An electrode 300 capable of measuring a bioelectric signal, which is a signal of a current or a voltage type, generated by muscles or nerve cells on the outer wall of the intracoronary tube, And a connection unit 700 which is a lead for connecting the display unit (not shown) with the electrode.

By inserting the intracorporeal device integrated with the bioelectrical signal measuring device into the human body during surgery, it is possible to prevent low ventilation, hypoxia, and intubation, and also to measure bioelectrical signals To assist in safe surgery.

Such an integrated device tries to overcome these limitations through a wireless transceiver because there is a problem such as obstruction of view of a doctor and restriction of space due to the connection part 700 due to the connection part 700. To this end, the present invention separates a bioelectrical signal measuring device from an endotracheal tube. The measuring device is also capable of wireless transmission and is attachable to the outer circumferential surface of the intracoronary tube.

Fig. 2 shows a bioelectrical signal measuring apparatus of the present invention. The measuring apparatus includes a thin film electrode 11, a transmitter 12, and a battery 13 on an insulating film 10 having an adhering portion 14 so as to be adhered to an outer circumferential surface of the intracoronary tube, do. The electrode (11) is arranged on the side opposite to the adhered portion of the insulating film so as to come into contact with the muscle or nerve region where one end of the intracoronary tube is located. The transmitter 12 wirelessly transmits the bioelectrical signal detected by the thin-film electrode, and an individual element such as an oscillator, an amplifier, an antenna, and a switch is housed in a micro ASIC (Application Specific Integrated Circuit) chip , And any of those known in the art can be used. The battery 13 supplies power for operating the transmitter.

Electrodes for sensing bio-electrical signals in contact with the muscles or nerves may be metal, alloy or non-metallic conductors that can be inserted into the human body. Electrodes for contact with the muscles of the human body, May be used. In one embodiment of the present invention, a plurality of the thin film electrodes 11 may be used, and the insulating film may be printed with conductive ink. The conductive ink may be any conductive material such as a conductive metal ink, a conductive carbon ink, or a conductive polymer ink. In an embodiment of the present invention, the battery 13 for operating the transmitter 12 may be a lithium battery having high stability in the body. The lithium battery uses a lithium or lithium mixture as a negative electrode. The battery has a long operating time and has an output voltage twice that of a manganese battery or an alkaline battery. When a solid electrolyte is used, there is no leakage of the battery. It is inserted into the human body for driving.

3 is a cross-sectional view of a portion connecting A-A 'in FIG. The bonding portion 14 is placed on the lower surface of the insulating film 10 and the electrode 11 is exposed on the upper surface to measure the bioelectric signal. In one embodiment of the present invention, the insulating film is a flexible printed circuit board having good workability, excellent thermal and chemical resistance, less dimensional change, strong heat and flexibility, and easy to adhere to the outer surface of the inner tube. Lt; / RTI > The flexible printed circuit board may be made of PET (Polyethylene Telephthalate), PEN (Polyethylene Naphthalate) or PI (Polyimide). The bonding portion 14 positioned on the lower surface of the insulating film can be used as long as it has adhesiveness and is harmless to the human body.

FIG. 4 is a conceptual diagram of an internal tube with an apparatus 1 for measuring bio-electrical signals of FIG. 2 attached thereto. In one embodiment of the present invention, the measuring device is inserted into the oral cavity during surgery and used in contact with the hind paw (including the vocal cord) and the laryngeal nerve (including the laryngeal nerve). By transmitting the biomedical signals wirelessly, it is possible to improve the use distance restriction due to the limitation of the wire length between the transmitter and the receiver, the obstruction of the operation view of the wire, and the risk of wire disconnection. In an embodiment of the present invention, a reception and display unit (not shown) for receiving a bio-electrical signal wirelessly transmitted from the transmitter 12 to an intraoperative neurological monitoring system is used, Any of the above can be used.

5 is a conceptual diagram of a bioelectric signal measuring apparatus attached to an outer circumferential surface of an endotracheal tube and having a transmitter placed on the face of a patient during surgery. An insulating film (20) composed of a head having a large area and a tail extending from the head, the insulating film (20) being attachable along the length of the intracorporal inner tube inserted into the human body, A plurality of thin film electrodes (21) arranged in contact with the muscles or nerve sites where one end of the intracoronary tube is located, and a plurality of thin film electrodes (21) located at the tail of the insulating film and electrically connected at one end to the thin film electrode And the other end includes a lead 25 leading to the end of the tail. The thin film electrode 21 is exposed to the outside and the lead 25 is covered and connected to a lead 26 extending from the insulating film and the lead 26 is positioned outside the human body To a transmitter (not shown). In an embodiment of the present invention, the conductive wire 25 is used by insulating coating an electric conductive tape or conductive ink.

Electrodes for sensing bio-electrical signals in contact with the muscles or nerves may be metal, alloy or non-metallic conductors that can be inserted into the human body. Electrodes for contact with the muscles of the human body, May be used. In one embodiment of the present invention, there are a plurality of the thin film electrodes 21, and they can be used by printing conductive ink on the insulating film. The conductive ink may be any conductive material such as a conductive metal ink, a conductive carbon ink, or a conductive polymer ink. Since the wireless transmitter (not shown) is located outside the body, it is not limited in size, and any wireless transmitter known in the art can be used.

6 is a cross-sectional view of a portion connecting B-B 'of FIG. A conductive line 25 is located on the lower surface of the insulating film 20 and is located at the tail of the insulating film and electrically connected to the thin film electrode at one end and to the bottom of the tail at the other end. An electric conductive tape for bonding is used, or a conductive ink is printed on one side of the tail portion, followed by insulation coating. The bonding portion 24 positioned on the lower surface of the insulating film can be used as long as it has adhesiveness and is harmless to the human body.

FIG. 7 is a conceptual diagram of an in-hospital internal tube to which the bio-signal measuring device 2 of FIG. 5 is attached. In one embodiment of the present invention, the measuring device is inserted into the oral cavity during surgery to be used in contact with the hind paw (including the vocal cord) or the laryngeal nerve (including the back laryngeal nerve). A transmitter (not shown) connected to the lead 26 extending from the insulating film 20 is positioned around the face of the patient and transmits the bioelectrical signal wirelessly. By transmitting biomedical signals wirelessly, it is possible to limit the use distance due to the limitation of the wire length between the transmitter and the receiver, and to prevent the doctor's view of the operation and the risk of wire disconnection. In one embodiment of the present invention, a receiving and displaying unit (not shown) for receiving a bio-electrical signal wirelessly transmitted from the transmitter to an intraoperative neurological monitoring system is used. Like the wireless transmitter, any of those known in the art It is available. The transmitter and the components of the nervous system monitoring system can be used repeatedly.

According to another embodiment of the present invention, the electrical signals of the anal sphincter and the urethra sphincter can be measured. The electromyogram of anal sphincter and urethral sphincter monitors the nerve damage during spine or pelvic surgery. The anal sphincter and urethral sphincter bioelectrical signal measuring device allows the electrode to be positioned at the site where the sphincter muscle is located, and can be deformed according to the structure of the anus and urethra.

1. A bioelectrical signal measuring device detecting unit including a transmitter
2. Detection device of bioelectrical signal
10. Insulation film
11. Thin film electrode 12. Transmitter
13. Battery 14. Adhesive
20. Insulation film 21. Thin film electrode
24. Bottom of insulation film 25. Insulation film tail conductor
26. Conductor wire extending from insulating film
100. Beveled Tip 200. Cuff
300. Electrode 400. Pilot balloon
500. Inflating tube 600. Connector
700. Connection

Claims (17)

An insulating film that can be attached to an outer circumferential surface of an inner body of a human body inserted into a hole of a human body;
A plurality of thin film electrodes arranged so as to contact muscles or nerve parts where one part of the inner body tube is located;
A transmitter for wirelessly transmitting the bioelectric signal detected by the thin film electrode;
A conductor electrically connecting the thin film electrode and the transmitter; And
And a battery for operating the transmitter,
Wherein the electrode, the transmitter, the lead, and the battery are disposed on the insulating film,
Apparatus for measuring bioelectric signals.
The method according to claim 1,
The hole of the human body is a trachea,
Apparatus for measuring bioelectric signals.
The method according to claim 1,
The hole of the human body is an anus or urethra,
Apparatus for measuring bioelectric signals.
The method according to claim 1,
Wherein the plurality of thin film electrodes are printed with conductive ink,
Apparatus for measuring bioelectric signals.
The method according to claim 1,
Wherein the insulating film is made of a flexible printed circuit board,
Apparatus for measuring bioelectric signals.
6. The method of claim 5,
The flexible printed circuit board may be made of PET (Polyethylene Telephthalate), PEN (Polyethylene Naphthalate) or PI (Polyimide)
Apparatus for measuring bioelectric signals.
The method according to claim 1,
The applied muscles of the above measuring device include a hind paw (including sordid muscle), an anal sphincter, or a urethral sphincter,
Apparatus for measuring bioelectric signals.
The method according to claim 1,
The application nerves of the measuring device include the laryngeal nerve (including the laryngeal nerve)
Apparatus for measuring bioelectric signals.
The method according to claim 1,
The battery for operating the transmitter is a lithium battery,
Apparatus for measuring bioelectric signals.
10. The method according to any one of claims 1 to 9,
And a receiving and displaying unit for receiving the bioelectric signal from the transmitter,
Apparatus for measuring bioelectric signals. An insulating film which is composed of a head having a large area and a tail leading to the head and which can be attached along the length of an inner tube of a human body inserted into a hole of the human body;
A plurality of thin film electrodes arranged at the head portion which is opposite to the surface of the insulating film to be adhered to the human body tube and arranged so as to contact muscles or nerve portions where one portion of the human body inner tube is located; And
And a conductive line located at a tail of the insulating film, one end of which is electrically connected to the thin film electrode and the other end of which leads to an end of the tail,
Apparatus for measuring bioelectric signals.
12. The method of claim 11,
Wherein the plurality of thin film electrodes are printed with conductive ink,
Apparatus for measuring bioelectric signals.
12. The method of claim 11,
The applied muscular region of the measuring device may include the hind paw (including the vocal cord), the anal sphincter, or the urethral sphincter,
Apparatus for measuring bioelectric signals.
12. The method of claim 11,
The application nerves of the measuring device include the laryngeal nerve (including the laryngeal nerve)
Apparatus for measuring bioelectric signals.
12. The method of claim 11,
Wherein the lead wire is formed by inserting an electric lead tape on one side of the tail portion and then inserting the lead wire,
Apparatus for measuring bioelectric signals.
12. The method of claim 11,
Wherein the conductive wire is printed on one side of the tail with conductive ink,
Apparatus for measuring bioelectric signals.
17. The method according to any one of claims 11 to 16,
A transmitter connected to the human body inner tube which is not inserted into the human body and protruded out of the body;
And a receiving and displaying unit for receiving the bioelectric signal from the transmitter,
Apparatus for measuring bioelectric signals.

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