KR101458172B1 - Method for manufacturing dialysate using reverse injection of reverse osmotic water - Google Patents

Abstract

The present invention relates to an apparatus and a method for manufacturing a dialysis liquid using the reverse input of RO number, wherein RO water is supplied from the bottom to the top of the cartridge in which the sodium bicarbonate powder in powder form as a raw material for preparing the dialysis liquid is stored, And then discharged to the upper portion of the cartridge to store the powder. At this time, the powder is mixed with the upper and lower edges of the cartridge, The dialysis solution can be completely melted without remaining and the dialysis solution having conductivity required for dialysis can be produced.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an apparatus and a method for manufacturing a dialysis liquid,

More particularly, the present invention relates to an apparatus and a method for manufacturing a dialysis liquid using reverse osmosis (RO) water. More particularly, the present invention relates to an apparatus and a method for manufacturing a dialysis liquid, Mixing the solution to prepare a dialysis solution, discharging the solution to the upper portion of the cartridge, and storing the solution, thereby completely dissolving the remaining powder on the upper and lower edges of the cartridge without leaving the powder, And more particularly, to an apparatus and a method for manufacturing a dialysis liquid using the reverse input of a dialysis liquid.

In general, there are methods of transplanting hemodialysis, peritoneal dialysis, and kidneys as a way for chronic renal failure patients to lose their kidney function due to various diseases.

Among these methods, kidney transplantation methods can provide kidneys from a family member, a relative, and a healthy kidney. However, through various surveillance tests, only when a donor is completely healthy and determined to live healthy with one kidney after the operation, Most transplant recipients are extremely limited in their ability to deliver kidneys, so most chronic renal failure patients rely on hemodialysis and peritoneal dialysis.

On the other hand, hemodialysis and peritoneal dialysis are new therapies for patients with chronic renal failure, in which the blood of a patient with accumulated waste products and dialysate having a composition similar to the extracellular fluid of a normal person flow in opposite directions, The waste is removed by the principle of diffusion by the concentration difference and the difference of the hydrostatic pressure is made, and the plasma is filtered to remove the excessive moisture in the body.

Of these, the hemodialysis method requires dialysis of the dialysis fluid using a dialyzer after the patient visits the hospital. Usually, the dialysis fluid is dialyzed for 4 hours once a week and 12 hours a week for 3 times a week. do.

At this time, the dialysis solution used for hemodialysis is generally manufactured by a manufacturer such as a pharmaceutical company and supplied to a hospital. For example, a conventional dialysis solution is prepared by adding a powder (sodium bicarbonate) as a raw material of a dialysis solution into a semi- , And the number of ROs suited to the ratio of the powders is supplied, followed by stirring through an impeller.

As another example, Korean Patent Application No. 10-2005-7019019 discloses a method capable of analogizing conventional dialysis solution production.

As shown in FIG. 1, the dialysis solution according to the related art of the other example has an inner space 10 for receiving a particulate material 20 such as a powder, Wherein the cartridge (9) has first and second filters (23 and 24) at the top and bottom to allow passage of liquid but prevent passage of the particulate material (20) A liquid such as water is introduced into the internal space 10 through the inlet 21 disposed in the upper portion of the cartridge 9 and the powder and the water introduced into the internal space 10 are mixed through the inlet 21 And the mixed dialysis liquid is discharged through the outlet 22 disposed at the lower portion of the cartridge 9 to manufacture.

Korean Patent Application No. 10-2005-7019019 (entry of PCT / SE2004 / 000557 in Korea), Applicant: Gambrundung Diaabe, filed on Apr. 7, 2004

In the method of manufacturing a dialysis solution according to an example of the related art as described above, the powder contained in a separate bag is put into a mix tank, dust of the powder is discharged to the outside, a large amount of raw material for the dialysis solution is lost, and the inner and outer surfaces of the mix tank are dirty However, there is a problem that it is necessary to dispose of the remaining amount remaining in the dialysis liquid container without using it.

In another method of manufacturing the dialysis solution according to another example of the related art, water having a large pressure is supplied straight from the inlet of the upper portion of the cartridge to the outlet of the lower portion of the cartridge, As the water from the upper part of the bar is supplied, the powder around the upper and lower edges of the inside of the cartridge becomes insoluble, so that the preparation of the dialysis solution is not properly performed and the proper conductivity (reference value 40 to 42 mS / cm) There is a problem that the dialysis solution having the above-mentioned problems can not be produced.

SUMMARY OF THE INVENTION Accordingly, the present invention has been made to solve the above problems, and it is an object of the present invention to provide a method of supplying RO water (Reverse Osmotic Water) from the lower part to the upper part of a cartridge containing powdered sodium hydrogencarbonate, A dialysis liquid is prepared by mixing with a powder and discharged to the upper portion of the cartridge to store the powder therein so as to completely melt the powder remaining on both upper and lower edges of the inside of the cartridge and to prepare a dialysis liquid having necessary conductivity for dialysis And an apparatus and a method for manufacturing a dialysis liquid using reverse input of RO number.

That is, an object of the present invention is to provide a method of spraying a large number of ROs from a lower portion of a cartridge to an upper portion near an inner center of the cartridge, and then powder is first mixed up by the pressure of the RO water, A part of the unheated powder falls to both sides of the cartridge and is mixed with the secondarily mixed so that the powder solution does not remain around the upper and lower edges of the inside of the cartridge and the powder inside the cartridge is completely melted through the RO water And to provide a method for manufacturing a dialysis liquid using the reverse input of RO number so as to produce a dialysis liquid satisfying a standard conductivity.

These and other objects of the present invention will be apparent to those skilled in the art without departing from the scope of the present invention by the appended claims.

To achieve the above object, according to one aspect of the present invention, there is provided an apparatus for manufacturing a dialysis liquid using the back-flow of RO water, comprising: a back plate installed vertically upright; A lower fixing part 120 fixed to a lower portion of one side of the back plate 110 and having a flow path for supplying RO water supplied from the RO water supply tank 105 therein; A first needle unit 130 inserted into the lower fixing part 120 to penetrate the inflow projection cap 191 at the lower end of the cartridge 190 through punching and having a flow path to supply RO water; First and second guide bars 141 and 142 to which one end is inserted and fixed to the lower fixing part 120; An upper fixing part 150 fixed to one side of the back plate 110 and inserted and fixed in the other end of the first and second guide bars 141 and 142; A vertical adjustment part 160 inserted into the first and second guide bars 141 and 142 and configured to be movable up and down; The cartridge 190 is inserted into the upper and lower regulating part 160 to pierce the outflow protrusion cap 192 at the upper end of the cartridge 190 to form a flow path for discharging the dialysis solution produced in the cartridge 190 Two needle units 170; And a locking part 180 integrally provided at one side of the vertical adjustment part 160 for locking or unlocking the vertical adjustment part 160 to or from the second guide bar 142.

According to another aspect of the present invention, there is provided a method for manufacturing a dialysis solution using the back-flow of RO water, comprising the steps of: (A) (310) of the upper needle unit (130) of the upper and lower regulating unit (160), and positioning the outlet cap (192) provided at the upper end of the upper needle unit (B) the upper and lower regulating portions 160 are forced upwardly and downwardly so that the inflow projection caps 191 of the cartridge 190 are inserted through the first needle unit 130 and the second needle unit 170, And punching the outflow protrusion cap 192 (S320); (C) According to the control of the control unit 200, the RO water is supplied from the RO water supply tank 105 through the flow path formed in the lower fixing unit 120 and the first needle unit 130 to the inflow projection at the lower end of the cartridge 190 To the cap 191 (S330); (D) mixing and dissolving the RO water supplied through the inflow projection cap 191 at the lower end of the cartridge 190 and sodium bicarbonate powder through step (C) (S340); And (E) storing the melted dialysis solution through the microfilter 193 in the cartridge 190 and storing it in the storage tank 195 (S350).

Preferably, the powder not melted through the step (D) is prevented from passing through the micro-filter 193 in the cartridge 190, (S360) a process of melting again by being recirculated upward to the upper part through the water. And (G) storing the dialysate prepared in step (F) through the microfilter 193 in the cartridge 190 and storing the dialysate in the storage tank 195 (S370).

According to the apparatus and method for manufacturing a dialysis liquid using the reverse input of the RO number according to the present invention, RO water is supplied from the bottom to the top of the cartridge in which the sodium bicarbonate powder in powder form, which is the raw material for preparing the dialysis liquid, is stored, And then discharged to the upper part of the cartridge and stored. By doing so, the upper and lower edges of the inside of the cartridge are separated from the upper and lower edges of the cartridge, It is possible to completely dissolve the powder so as not to remain and at the same time to prepare a dialysis liquid having conductivity required for dialysis.

Additional features and advantages of the present invention will become more apparent from the following description.

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a view for explaining an example of a method for producing a dialysis liquid according to the prior art. Fig.
2 is a view showing a configuration of an apparatus for producing a dialysis liquid using the back-flow of RO water according to the present invention.
3 is a photograph showing the configuration of an apparatus for producing a dialysis liquid using the reverse input of RO number according to an embodiment of the present invention.
4 is an exploded cross-sectional view and a perspective view of a first needle unit according to the present invention.
5 is a cross-sectional view and a perspective view of a needle according to the present invention.
6 (a) and 6 (b) are diagrams showing the structure of the lock portion when opening and closing according to the present invention.
FIG. 7 is a flowchart showing a method for manufacturing a dialysis solution using the reverse input of RO number according to the present invention. FIG.
8 is a view showing an example of an apparatus for producing a dialysis liquid used in an experiment in which a plurality of cartridges are attached.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An apparatus and a method for manufacturing a dialysis liquid using the back-flow of RO water according to a preferred embodiment of the present invention will be described in detail with reference to the accompanying drawings.

Prior to the detailed description of the present invention, the same or corresponding components in the drawings are denoted by the same reference numerals, and if a detailed description of related known configurations or functions is deemed to blur the gist of the present invention, Is omitted.

Also, in the present specification, the following embodiments and embodiments are to be considered as being illustrative and not restrictive, and the invention is not to be limited to the details given herein but is to be accorded with the scope of the appended claims and their equivalents, It can be changed to another embodiment.

First, an apparatus for manufacturing a dialysis liquid using the back-flow of RO water according to an embodiment of the present invention will be described with reference to FIGS. 2 to 6. FIG.

FIG. 2 is a view showing a configuration of an apparatus for producing a dialysis liquid using the reverse input of RO number according to the present invention, and FIG. 3 is a view showing the configuration of an apparatus for producing dialysis liquid using the back- FIG. 5 is a cross-sectional view and a perspective view of a needle according to the present invention, and FIGS. 6 (a) and 6 (b) are cross- Fig. 7 is a view showing the configuration when the lock portion is opened and closed.

2 and 3, an apparatus for manufacturing a dialysis liquid according to an embodiment of the present invention includes a back plate 110, a lower fixing unit 120, a first needle unit 130, first and second And includes the guide bars 141 and 142, the upper fixing unit 150, the upper and lower control unit 160, the second needle unit 170, the locking unit 180, the cartridge 190, and the control unit 200.

Specifically, the back plate 110 is vertically installed upright, and includes a hole through which the lower fixing part 120 and the upper fixing part 150 can be coupled through a fastening means such as a bolt, a RO water supply tank 105 and a reservoir tank 195 or a hole into which a hose can be inserted.

The lower fixing part 120 has one or more holes formed with threads and is coupled to a hole formed in the back plate 110 through a bolt and is fixed to a lower side of one side of the back plate 110, A flow path is formed so that the RO water supplied from the tank 105 can be supplied.

At this time, the number of ROs from the RO water supply tank 105 is controlled by the control unit 200 so that the first solenoid valve 106 is turned on and the RO water supply tank 105 and the first solenoid valve It is preferable that the flow rate, the speed and the pressure are regulated and supplied through a regulator (not shown) provided between the valves 106.

The first needle unit 130 is inserted into the lower fixing part 120 to penetrate the inflow projection cap 191 at the lower end of the cartridge 190 through punching to form a flow path, A fitting valve 131 for holding and holding a pipe connected to the RO water supply tank 105 at one end or the other end of the hose as shown in Fig. 4, A connection pipe 132 for inserting and fitting a fitting valve 131 into a hole formed at one side and inserting and screwing a needle 133 into a hole formed at the upper side so as to form a flow path between them, A needle 133 having one end inserted into a hole formed at an upper side of the needle 133 and having a sharp punching unit formed at the other end thereof and a needle 133 for receiving the RO water and the dialysis solution from the outside, The upper outer circumferential surface of the tube 132 and the inner circumferential surface thereof An outer circumferential surface of the needle 133 and an inner circumferential surface of the outflow preventing tube 135 to prevent the solution from leaking out during the preparation of the dialysis liquid, (134).

5, a thread 133a is formed on the outer circumferential surface of the lower portion of the needle 133 so that the needle 133 can be inserted into the coupling tube 132 and screwed thereto, A sharp punching unit 133b is formed so as to protrude a lower inlet protrusion cap 191 and a middle body portion 133c is formed at a middle portion of the body portion 133c so that the O- And an RO water inlet hole 133d is formed at a central portion thereof so that the RO water supplied through the RO water supply tank 105 can be introduced into the RO pump water tank 133. The RO water is smoothly introduced into the outer peripheral surface of the puncher 133b An RO water inlet auxiliary hole 133e communicating with the RO water inlet hole is formed.

The RO water inlet hole 133d is formed so that the cover of the inlet protrusion cap 191 of the cartridge 190 punched through the punching unit 133b flows into the inlet of the RO water inlet hole 133d And the punching unit 133b is formed to have a smaller diameter than that of the RO water inlet auxiliary hole 133e. The punching unit 133b has an end portion and an end surface of which are protruded toward the upper end in an acicular shape, And it is preferably tapered toward the water inlet hole 133d.

Meanwhile, one end of the first and second guide bars 141 and 142 is inserted into the lower fixing part 120 and fixed.

The upper fixing part 150 has at least one threaded hole and is bolted together with a hole formed in the upper part of the back plate 110 to be fixed to one side of the back plate 110, The other ends of the second guide bars 141 and 142 are inserted and fixed.

The upper and lower control part 160 is inserted into the first and second guide bars 141 and 142 through two holes formed in the vertical direction and is vertically movable. A second needle unit 170 having the same configuration as that of the first needle unit 130 inserted in the first needle unit 130 is inserted and connected to the first needle unit 130 through a pipe or a hose The dialysis solution produced by mixing in the cartridge 190 is discharged to the storage tank 195 and stored.

The second needle unit 170 is inserted into the upper and lower regulating unit 160 to pierce the outflow protrusion cap 192 at the upper end of the cartridge 190 to form a flow path, Since the first needle unit 130 having the first needle unit 133 is formed in a downward direction, the structure of the first needle unit 130 is the same as that of the first needle unit 130, and a detailed description thereof will be omitted.

The locking portion 180 is integrally provided at one side of the vertical adjustment portion 160 by a coupling means such as a bolt to lock the vertical adjustment portion 160 to the second guide bar 142, A handle 181 for locking and unlocking the up / down control part 160 to the second guide bar 142 in accordance with the left and right rotations, as shown in FIGS. 6 (a) and 6 (b) A pressing cam 182 integrally connected to one end of the handle 181 and eccentrically moved to move according to the movement of the handle, a through hole 183 inserted into the second guide bar 142, A pressing piece 184 urged toward the through hole 183 in response to the urging of the pressing cam 182 and a pressing piece 184 urging the second guide bar 142 in accordance with the pressing of the pressing piece 184. [ And a pressing member 185 made of a rubber material which presses the pressing member 185.

6A is a side view of the upper and lower control unit 160 integrally formed with the lock unit 180 as the handle 181 is positioned on the right side, 6B shows a state in which the handle 181 is moved to the upper and lower portions of the second guide bar 142 and the lock portion 180 is closed as the handle 181 is positioned on the left side, And a vertical guide 160 integrally formed with the locking part 180 is fixed to the second guide bar 142. As shown in FIG.

The cartridge 190 has a conical shape storing a powdered sodium bicarbonate as a raw material of the dialysis liquid and having a larger diameter as it extends from the lower part to the upper part, The upper needle outlet 191 is punched through the first needle unit 130 to be fixed to the lower fixing part 120 and the upper outflow protrusion cap 192 closed by the thin mesh filter is inserted into the second needle unit 130. [ And is fixed to the upper and lower regulating unit 160 while being punched through the first needle unit 170 to be connected to the inflow projection cap 191 at the lower portion of the cartridge 190 from the RO water supply tank 105 through the first needle unit 130 The dialyzed solution is prepared by mixing the inflowed RO number and the powder and the prepared dialysis solution is discharged and stored in the storage tank 195 through the outflow protrusion cap 192 on the upper part of the cartridge 190 and the second needle unit 170 .

At this time, a mesh-shaped microfilter 193 is formed at an upper portion, a lower portion, or an upper portion of the cartridge 190, preferably at an upper portion of the cartridge 190, Filter 193 so that only the dialysate prepared by melting through RO water can pass through the microfilter 193 and be stored in the storage tank 195.

That is, the powder that is not completely dissolved in the cartridge 190 sinks downward due to failure to pass through the micro filter 193 in the cartridge 190, (Reference value 40 to 42 mS / cm) required for dialysis by being completely dissolved while being circulated upward.

On the other hand, the control unit 200 is a control panel provided with a start button, an end button, a mixing button, a storage button, a time setting unit, and a program necessary for dialysis, Controls the solenoid valve 106, the regulator and the second solenoid valve 194 provided at one side of the storage tank 195 to turn on / off and to mix and store the dialysis liquid for a predetermined time.

Hereinafter, a method for manufacturing a dialysis solution using the reverse input of RO water according to the present invention will be described with reference to FIG. 7 and FIG.

FIG. 7 is a flow chart showing a method for preparing a dialysis liquid using the back-up of RO number according to the present invention, and FIG. 8 is a view showing an example of a dialysis solution production apparatus used in an experimental example with a plurality of cartridges attached thereto.

7, the method for manufacturing a dialysis liquid using the reverse input of the RO number according to the present invention is characterized in that the inflow projection cap 191 provided at the lower end of the cartridge 190 is inserted into the lower fixing part 120 1 needle unit 130 and the outflow protrusion cap 192 provided at the upper end is positioned in the second needle unit 170 of the up-down adjustment unit 160 (S310).

Next, the upper and lower regulating portions 160 are forcibly urged upward and downward so that the inflow of the cartridge 190 through the needle of the first needle unit 130 and the needle of the second needle unit 170 The protrusion cap 191 and the outflow protrusion cap 192 are punched (S320).

Next, the control unit 200 sets start, end, mix, and store buttons and time, and sets the first solenoid valve 106, the regulator, and the storage tank (not shown) provided at one side of the RO water supply tank 105 And the second solenoid valve 194 provided on one side of the first needle unit 195 and the second solenoid valve 194 on / The RO number is supplied to the inflow projection cap 191 at the lower end of the cartridge 190 (S330).

In step S340, the dialyzer solution is prepared by mixing the RO water supplied through the inflow projection cap 191 at the lower end of the cartridge 190 with the sodium bicarbonate powder in powder form, which is the raw material of the dialysis solution, and dissolving it in step S330.

In step S350, the dialysis solution prepared in step S340 is passed through the microfilter 193 in the cartridge 190 and stored in the storage tank 195 (S350).

At this time, the completely unmelted powder is not allowed to pass through the microfilter 193 in the cartridge 190, so that the powder does not pass through the cartridge 190 and flows downward through the RO water supplied from the lower portion of the cartridge 190 And is again raised and circulated to melt again (S360).

In step S370, the dialysis solution is completely dissolved by passing through the microfilter 193 in the cartridge 190 and stored in the storage tank 195 in step S360.

A conductivity measurement sensor (not shown) is provided between the up-down control unit 160 and the storage tank 195, and the conductivity of the dialysis liquid prepared through the steps S350 and S370 is set to a reference conductivity The controller 200 turns off the second solenoid valve 194 and then turns off the dialysis liquid (not shown) that is not satisfied with the reference conductivity by a separate discharge tank (S380).

8, the plurality of cartridges 190 are fixed through the lower fixing part 120 and the vertical adjustment part 160, and then the RO water is supplied from the upper part of the cartridge to the lower part of the cartridge The results of measurement of the conductivity of the dialysis solution prepared in Experiment 1 and the conductivity of the dialysis solution prepared in Experiment 2 in which the RO number according to the present invention is supplied from the lower portion to the upper portion of the cartridge will be described .

At this time, the flow rate of the RO water supplied through the RO water supply tank 105 and the regulator was measured at intervals of 0.5 L / min from 1 L / min to 4 L / min, and the conductivity of the resulting hydrogen carbonate dialysis liquid was measured (Conductivity reference value 40 ~ 42mS / cm).

flux
(L / min) Time (min) Production amount (L) conductivity
(mS / cm) conductivity
Average 1.0 12.3 12.3 35.5 35.4 12.5 12.5 35.2 12.3 12.3 35.6 1.5 8.2 12.3 35.2 34.9 8.4 12.6 34.8 8.5 12.75 34.6 2.0 6.0 12.0 36.4 36.3 6.0 12.0 36.5 6.1 12.2 36.1 2.5 4.8 12.0 36.2 36.0 5.0 12.5 35.8 4.9 12.25 36.1 3.0 4.2 12.6 35.2 34.7 4.3 12.9 34.8 4.5 13.5 34.1 3.5 3.9 13.65 33.7 33.6 3.8 13.3 33.2 3.9 13.65 33.8 4.0 3.5 14.0 32.2 No experiment Destruction Destruction Destruction

[Table 1] Results of Experiment 1 (prior art)

As shown in Table 1, the method of preparing the dialysis solution by supplying the RO water according to the prior art from the top to the bottom of the cartridge is as follows. When the RO water is supplied at 2 L / min and 2.5 L / min, (40 ~ 42mS / cm), which is the highest value of the conductivity. In other words, the efficiency decreased with the increase of the flow rate, and the experiment was stopped because the cartridge was broken at 4 L / min.

flux
(L / min) Time (min) Production amount (L) conductivity
(mS / cm) conductivity
Average 1.0 8.5 8.5 40.4 40.6 8.5 8.5 40.6 8.4 8.4 40.8 1.5 5.4 8.1 41.4 41.4 5.5 8.25 41.1 5.4 8.1 41.6 2.0 4.0 8.0 41.3 41.3 4.1 8.2 41.1 4.0 8.0 41.4 2.5 3.5 8.75 40.2 40.1 3.6 9 39.8 3.5 8.75 40.3 3.0 3.3 9.9 39.0 39.5 3.0 9 39.9 3.1 9.3 39.7 3.5 2.8 9.8 39.3 39.0 3.0 10.5 38.8 2.8 9.8 38.8

[Table 2] Results of Experiment 2 (Present invention)

On the other hand, as shown in Table 2, according to the method for manufacturing the dialysis liquid supplying the RO number from the lower part to the upper part of the cartridge according to the present invention, a conductivity value substantially equal to the reference conductivity at 1.0 L / min to 2.5 L / .

That is, in the method of injecting the RO water from the lower portion of the cartridge 190 and putting the dialysis solution passing through the microfilter 193 in the cartridge 190 into the storage tank 195, Good conductivity values were obtained.

At this time, the conductivity according to the temperature of the RO water was measured with the above <Experiment 2>, and the measurement results are shown in Table 3 below.

Temperature (℃) Time (min) Production amount (L) conductivity
(mS / cm) 5 8 12 36.4 10 6 9 40.1 15 5.6 8.4 40.9 20 5.5 8.1 41.4

[Table 3] Relationship between RO Number Temperature and Conductivity

That is, the conductivity of the dialysis solution was checked by changing the temperature of the RO water at 5 ° C, 10 ° C, 15 ° C, and 20 ° C using an instantaneous hot water heater. As a result, the best conductivity was obtained when the RO water temperature increased. It is most preferable that the temperature of the RO water supplied to the lower portion of the cartridge 190 through the RO water supply tank 105 is approximately 10 ° C to 20 ° C.

While the present invention has been described in connection with what is presently considered to be practical exemplary embodiments, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, Of course.

That is, in one embodiment of the present invention, a single dialysis solution is prepared by mounting one cartridge, but it is needless to say that a dialysis solution can be manufactured by mounting a plurality of cartridges as shown in FIG.

110: back plate 120: lower fixing portion
130: first needle unit 141: first guide bar
142: second guide bar 150: upper fixing part
160: Up and down adjustment unit 170: Second needle unit
180: locking portion 190: cartridge
200:

Claims (8)

An apparatus for producing a dialysis liquid by using the reverse input of RO number (purified water)
A vertically erected back plate 110;
A lower fixing part 120 fixed to a lower portion of one side of the back plate 110 and having a flow path for supplying RO water supplied from the RO water supply tank 105 therein;
A first needle unit 130 inserted into the lower fixing part 120 to penetrate the inflow projection cap 191 at the lower end of the cartridge 190 through punching and having a flow path to supply RO water;
First and second guide bars 141 and 142 to which one end is inserted and fixed to the lower fixing part 120;
An upper fixing part 150 fixed to one side of the back plate 110 and inserted and fixed in the other end of the first and second guide bars 141 and 142;
A vertical adjustment part 160 inserted into the first and second guide bars 141 and 142 and configured to be movable up and down;
The cartridge 190 is inserted into the upper and lower regulating part 160 to pierce the outflow protrusion cap 192 at the upper end of the cartridge 190 to form a flow path for discharging the dialysis solution produced in the cartridge 190 Two needle units 170; And
And a locking part 180 integrally provided at one side of the vertical adjustment part 160 to lock or unlock the vertical adjustment part 160 to or from the second guide bar 142 A dialysis liquid production apparatus using the reverse input of RO number. The method according to claim 1,
The first needle unit (130)
A fitting valve 131 for holding and holding the other end of the hose connected to the RO water supply tank 105 at one end and a fitting valve 131 inserted into a hole formed at one side of the fitting valve 131, A needle 133 having one end inserted into the hole formed on the upper side of the connection pipe 132 and having a sharp punching unit formed at the other end thereof, An outflow preventing tube 135 which receives the needle 133 and prevents the RO water and the dialysis solution from flowing to the outside and the upper outer circumferential surface of the connecting tube 132 and the inner circumferential surface of the connecting tube 132 are coupled to each other, And an O-ring (134) inserted between the outer circumferential surface and the inner circumferential surface of the outflow preventing tube (135) to prevent the solution from leaking to the outside during preparation of the dialysis solution. The method according to claim 1,
The locking portion 180 may be formed,
A handle 181 for locking and unlocking the up / down control part 160 to / from the second guide bar 142 according to the rotation of the left and right sides, and a handle 181 integrally connected to one end of the handle 181, A through hole 183 inserted into the second guide bar 142 and a pressing cam 182 urged toward the through hole 183 in response to the urging of the pressing cam 182 And a pressing member (185) pressing the second guide bar (142) in accordance with the pressing of the pressing piece (184) in response to the movement of the pressing piece (184) . 4. The method according to any one of claims 1 to 3,
A micro filter 193 is formed on the cartridge 190 so that the powder not melted through the RO water can not pass through the micro filter 193 and only the dialysis solution melted through the RO water 193) and stored in the storage tank (195). A method for producing a dialysis solution using the reverse input of RO number (purified water)
(A) The inflow projection cap 191 provided at the lower end of the cartridge 190 is positioned in the first needle unit 130 of the lower fixing part 120 and the outflow projection cap 192 provided at the upper end is vertically adjusted (S310) in the second needle unit (170) of the first part (160);
(B) the upper and lower regulating portions 160 are forced upwardly and downwardly so that the inflow projection caps 191 of the cartridge 190 are inserted through the first needle unit 130 and the second needle unit 170, And punching the outflow protrusion cap 192 (S320);
(C) According to the control of the control unit 200, the RO water is supplied from the RO water supply tank 105 through the flow path formed in the lower fixing unit 120 and the first needle unit 130 to the inflow projection at the lower end of the cartridge 190 To the cap 191 (S330);
(D) mixing and dissolving the RO water supplied through the inflow projection cap 191 at the lower end of the cartridge 190 and sodium bicarbonate powder through step (C) (S340); And
(E) storing the dialyzed solution, which has been melted through the step (D), through the microfilter 193 in the cartridge 190 and storing it in the storage tank 195 (S350). A method for manufacturing a dialysis liquid using a reverse input. 6. The method of claim 5,
(F) The powder not melted through the step (D) is prevented from passing through the microfilter 193 in the cartridge 190, so that the powder is subdivided, and through the RO water supplied from the lower part of the cartridge 190 (S360) a process of melting again by being recycled to the upper part and circulating; And
(G) the step (S370) of passing the dialysate prepared in the step (F) through the microfilter 193 in the cartridge 190 and storing the dialysate in the storage tank 195 A method for manufacturing a dialysis liquid using reverse osmosis. The method according to claim 5 or 6,
(H) The conductivity of the dialysis liquid prepared through the step (E) or the step (G) through the conductivity measuring sensor provided between the up-down control unit 160 and the storage tank 195 may be set to the reference conductivity required for dialysis Further comprising the step (S380) of causing the control unit (200) to drain the dialysis solution not satisfying the reference conductivity to the drain tank (S380). The method according to claim 5 or 6,
The flow rate of the dialysis solution supplied from the lower portion of the cartridge 190 through the microfilter 193 in the cartridge 190 is 1.0 to 2.5 L / min,
Wherein the temperature of the RO water supplied to the lower portion of the cartridge (190) through the RO water supply tank (105) is 10 ° C to 20 ° C.

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