KR101250448B1 - Embolus forming in-vivo indwelling-coil and the makigng methods for Embolus forming in-vivo indwelling coil - Google Patents

Embolus forming in-vivo indwelling-coil and the makigng methods for Embolus forming in-vivo indwelling coil Download PDF

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KR101250448B1
KR101250448B1 KR1020100135693A KR20100135693A KR101250448B1 KR 101250448 B1 KR101250448 B1 KR 101250448B1 KR 1020100135693 A KR1020100135693 A KR 1020100135693A KR 20100135693 A KR20100135693 A KR 20100135693A KR 101250448 B1 KR101250448 B1 KR 101250448B1
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South Korea
Prior art keywords
coil
spiral
polygonal
primary coil
shape
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Application number
KR1020100135693A
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Korean (ko)
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KR20120073813A (en
Inventor
권오기
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권오기
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Priority to KR1020100135693A priority Critical patent/KR101250448B1/en
Priority to PCT/KR2011/000770 priority patent/WO2012091212A1/en
Publication of KR20120073813A publication Critical patent/KR20120073813A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027Type of occlusion
    • A61B17/12031Type of occlusion complete occlusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00526Methods of manufacturing

Abstract

The present invention relates to an induction coil for embolic formation, and in the present invention, the embolic coil is inserted into the blood vessel while being twisted along the blood vessel, and is twisted in a spiral direction along the inside of the blood vessel as well as in a straight vessel. By inserting along the inside of the blood vessel to facilitate and effectively attract the embolization coil.
In order to achieve the above object, in the present invention, a plurality of unit spiral coils formed by a primary coil formed by winding a wire in a spiral shape are formed as a polygonal primary coil so as to have a polygonal shape having a plurality of corner portions. Heat to remember
By providing a polygonal secondary coil that is formed in a spiral form with the polygonal primary coil as in the prior art, it has become possible to provide the in-body induction coil for embolization of the present invention which has been heat-treated to store this spiral shape.

Description

Embolus forming in-vivo indwelling-coil and the makigng methods for Embolus forming in-vivo indwelling coil}

The present invention relates to an embolic induction coil used for endovascular treatment of cerebral aneurysm, and more particularly, does not strongly press the vessel wall of cerebral aneurysm when it contacts the inner wall of the cerebral artery. The present invention relates to an induction coil for embolization and a method for manufacturing the same, which are capable of being attracted and filled with high density in the interior of the cerebral aneurysm.

Cerebral aneurysms are abnormal swelling of the cerebral artery, and the risk of rupture is higher than that of normal blood vessel walls, and when ruptured, severe cerebral hemorrhage, including bleeding, is caused.

In the treatment of cerebral aneurysms, a number of treatments for preventing rebleeding are performed by inserting separate embolic coils into an aneurysm by accessing an aneurysm through blood vessels along with an aneurysm clip through craniotomy.

The primary treatment target for cerebral aneurysms is to prevent rebleeding due to aneurysm rupture or re-rupture. The traditional treatment is cervical clip of an aneurysm by craniotomy.

Open the skull and look for blood vessels with an aneurysm and use metal clips to grab the neck of the aneurysm to prevent blood flow into the aneurysm.

With the development of a detachable embolic coil, a catheter that enters the blood vessel is inserted into the aneurysm. The catheter tip is inserted into the aneurysm, and a sufficient amount of the detachable embolic coil is inserted into the aneurysm. This makes it possible to cure rebleeding due to re-rupture of an aneurysm.

The advantage of such a separate embolic coil is that the coil can be removed from the coil pusher only when necessary, so that the aneurysm can be embolized without the blood flow disturbance of the mother artery by repeating the insertion and removal as necessary.

The embolic coil is introduced into the cerebral aneurysm via an appropriate catheter by an extruding means (inductor) detachably connected to the end thereof, and is separated from a predetermined portion and held in the body.

The body induction coil for embolization is used for endovascular treatment of cerebral aneurysm, which can be avoided craniotomy.

Such an induction body induction coil is separated according to its shape, and is generally classified into a spiral coil and a complex coil having a complicated shape.

In the case of the spiral coil 3 described above, as illustrated in FIG. 1, a primary coil spirally formed of a wire 7 made of a material such as platinum, silver, gold, palladium or tungsten ( 1) is heat-treated to remember the spiral image, and then it is heat-treated to memorize the spiral image again in a spirally formed state, and composed of the secondary coil 2, and at one end thereof to prevent damage to the inner wall of the blood vessel. The chip 4 is provided.

This spiral coil is inserted into the cerebral aneurysm through a catheter and installed.

On the other hand, in the case of the spiral coil 3 as described above, it is necessary to fill the inside of the cerebral aneurysm with the highest density in order to prevent the reopening of the cerebral aneurysm. In the case of the spiral coil 3, the spiral coil 3 only has one direction. Due to the winding, there is a limit to densely filling the inside of the cerebral aneurysm, and because it is filled in a spiral shape, the spiral primary coil 1 is filled in a spiral shape of the secondary coil 2 that remembers its shape. Because of the force is not distributed, there is a problem that the inner wall of the vessel with the same force.

In this problem, a complex coil 4 having a complicated shape is provided to fill the coil as closely as possible inside the cerebral aneurysm.

As shown in the accompanying drawings, as shown in FIG. 2, the primary coil 1 is formed in a spiral shape and heat-treated so as to remember the spiral shape, and then heat-treated in a state having a complicated shape to make a complicated secondary shape having a complicated shape. It is completed by configuring the coil 5.

The complex coil 4 having such a complicated shape has an advantage of densely filling the inside of the cerebral aneurysm as compared to the spiral coil 1.

In this case, however, the movement cannot be predicted during the recovery through the cardette while being inserted into the internal aneurysm and restored to the original memorized shape, that is, the shape of the complex secondary coil 5, and as described above, Even though the secondary coil 5 is formed in a spiral shape, the secondary coil 5 is intricately configured, and thus is filled in a spiral shape, and thus, the force is not dispersed and the inner wall of the blood vessel is contacted with the same force.

That is, the conventional embolic coil as described above has a problem that it is difficult to reliably be attracted to a severely curved cerebral aneurysm due to the problem that the direction of action of the force applied to the embolic coil when acting in the body acts only in one direction.

In the present invention, the embolization coil is inserted into the vessel while twisted along the vessel, so that the vessel is not only straight, but also curved vessels are inserted in the spiral along the inside of the vessel and are easily inserted into the vessel. To attract the forming coil.

In order to achieve the above object, in the present invention, a plurality of unit spiral coils formed by a primary coil formed by winding a wire in a spiral shape are formed as a polygonal primary coil so as to have a polygonal shape having a plurality of corner portions. Heat to remember

By providing a polygonal secondary coil that is formed in a spiral form with the polygonal primary coil as in the prior art, it has become possible to provide the in-body induction coil for embolization of the present invention which has been heat-treated to store this spiral shape.

When inserting the embolic induction body for the embolization of the present invention into the blood vessel, it is inserted into the spiral while passing through the inside of the blood vessel, which is inserted into the blood vessel while being spirally twisted inside the blood vessel, Even in the blood vessel portion having the bent portion is inserted into the spiral while twisting along the curved portion has a function that can be inserted very effectively in the curved portion of the vessel.

This action is because the conventional induction coil for embolization of the present invention maintains a circular shape, and therefore is always inserted in the direction of action in one direction. It can solve the disadvantages.

1 is a reference diagram showing a conventional spiral coil.
2 is a reference diagram of a composite coil;
3 is a reference diagram of the present invention.
4 is a reference diagram showing the main portion of Figure 3 extracted.
5 and 7 illustrate another embodiment of the present invention.
8 is a manufacturing process diagram of the coil according to the present invention;
9 to 11 is another manufacturing process diagram of the coil according to the present invention.

Hereinafter, the present invention will be described in detail with reference to FIGS. 3 to 7.

As in the prior art, the primary coil 1 formed in a spiral shape with a wire 7 made of platinum, silver, gold, palladium, or tungsten is heat-treated so as to remember the spiral shape, and then it is spirally formed again. In the spiral coil (3) consisting of a secondary coil (2) by heat treatment so as to store this spiral phase in

Polygonal primary coil 12 to have a polygonal shape having a plurality of unit spiral coils 11 formed by the primary coil 1 formed by winding the wire 7 in a spiral shape with a plurality of corner portions 14. ) And heat treated to remember the shape,

Provided is the embodied induction coil for embolization of the present invention which is heat treated to store the spiral shape by forming the polygonal secondary coil 13 that is formed spirally as the conventional polygonal primary coil 12.

In this case, as described below, the edge portion 14 is preferably configured such that the edge is curved so that the edge portion 14 does not irritate the inner wall of the vessel when inserted along the inside of the vessel.

The shape of the polygonal primary coil 12 is preferably in the form of a triangular primary coil 15, but the rectangular primary coil 16, the pentagonal primary coil 17 and the hexagonal primary coil 18 It may have a form of.

In this case, when the polygonal secondary coil 13 is formed of the polygonal primary coil 12, a plurality of edge portions 14 of the polygonal primary coil 12 are formed in the entire polygonal secondary coil 13. Each surface is formed of a plurality of surface spirals (19).

When inserting the embolic induction body coil of the present invention into the blood vessel by the surface helix 19, it is inserted into the spiral spiral while passing through the inside of the blood vessel.

That is, when the object is inserted by the screw formed on the surface of the screw, the screw is easily inserted into the object as the screw is twisted. Since the blood vessel is inserted into the spiral while bending along the curved portion, the function of being able to be inserted very effectively in the curved portion of the blood vessel.

This action is because the conventional induction coil for embolization of the present invention maintains a circular shape, and therefore is always inserted in the direction of action in one direction. It can solve the disadvantages.

Such a present invention can be manufactured by using the jig according to the present invention, which is illustrated by the accompanying drawings as follows.

As described above, as conventionally, the wire 7 is made of platinum, silver, gold, palladium, tungsten or the like and spirally wound on a jig 31 of a cross-sectional polygon having a plurality of edges 30 The heat treatment to memorize the wound shape completes the polygonal primary coil 12 having a plurality of edge portions 14 as described above.

Using such a polygonal primary coil 12, the polygonal secondary coil 13 is completed by spirally winding as in the prior art.

By this completion, the surface spiral portion 19 is formed on the surface of the polygonal secondary coil 13.

As shown in the accompanying drawings, the jig 31 has a plurality of jiges, as well as a triangular jig 40, a pentagonal jig 50, and a hexagonal jig 60. Although it is described to complete the polygonal secondary coil 13 by spirally winding the polygonal primary coil 12 having the corner portion 14, this is for explaining an embodiment of the present invention, a plurality of corner portions Of course, a method of constructing and manufacturing a secondary coil by constructing or manufacturing a polygonal primary coil of any type having 14 is within the scope of the present invention.

1: primary coil 2: secondary coil
3: spiral coil 11: unit spiral coil
12: polygon primary coil 13: polygon secondary coil
14: corner 15: triangle primary coil
16: square primary coil 17: pentagonal primary coil
18: hexagonal primary coil 19: surface helix

Claims (7)

The primary coil 1 spirally formed of a wire 7 of platinum, silver, gold, palladium or tungsten is heat-treated to remember the spiral phase, and then the spiral phase is formed in the spiral shape again. In the spiral coil 3 composed of a secondary coil 2 by heat treatment to be stored,
Polygonal primary coil 12 to have a polygonal shape having a plurality of unit spiral coils 11 formed by the primary coil 1 formed by winding the wire 7 in a spiral shape with a plurality of corner portions 14. And a heat treatment to memorize the shape thereof.
The method according to claim 1,
The corner portion 14 is embodied induction coil for embolization, characterized in that the end is configured to be curved.
The method according to claim 1,
The shape of the polygonal primary coil 12 is any one of a triangular primary coil 15, a rectangular primary coil 16, a pentagonal primary coil 17 or a hexagonal primary coil 18 Induction coil for embolization.
The method according to claim 1,
Embolization, characterized in that the plurality of edge portions 14 of the polygonal primary coil 12 is formed of a plurality of surface spirals 19 on the surface of the entire polygonal secondary coil 13, respectively. Induction coil for the body.
A wire 7 of platinum, silver, gold, palladium or tungsten is wound spirally on a jig 31 of a cross-sectional polygon having a plurality of edges 30 and then heat treated to remember the wound shape. After completing the polygon primary coil 12 with section 14,
The method of manufacturing an in-vehicle induction coil for embolization, characterized in that it is wound in a spiral shape using the polygonal primary coil (12) to produce a polygonal secondary coil (13).
The method according to claim 5,
Surface spiral portion (19) is formed on the surface of the polygonal secondary coil (13) manufacturing method of the embolic induction body induction coil.
The method of claim 6,
The jig (31) is a triangular jig, a hexagonal jig, a pentagonal jig or a hexagonal jig, characterized in that the manufacturing method of the in-body induction coil for embolization.
KR1020100135693A 2010-12-27 2010-12-27 Embolus forming in-vivo indwelling-coil and the makigng methods for Embolus forming in-vivo indwelling coil KR101250448B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020100135693A KR101250448B1 (en) 2010-12-27 2010-12-27 Embolus forming in-vivo indwelling-coil and the makigng methods for Embolus forming in-vivo indwelling coil
PCT/KR2011/000770 WO2012091212A1 (en) 2010-12-27 2011-02-07 Embolisation coil which is retained in the body, and a production method for an embolisation coil which is retained in the body

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020100135693A KR101250448B1 (en) 2010-12-27 2010-12-27 Embolus forming in-vivo indwelling-coil and the makigng methods for Embolus forming in-vivo indwelling coil

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KR20120073813A KR20120073813A (en) 2012-07-05
KR101250448B1 true KR101250448B1 (en) 2013-04-08

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WO (1) WO2012091212A1 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016044188A1 (en) * 2014-09-15 2016-03-24 Jones Donald K Intralumenal occlusion devices having improved properties

Citations (4)

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Publication number Priority date Publication date Assignee Title
US5649949A (en) 1996-03-14 1997-07-22 Target Therapeutics, Inc. Variable cross-section conical vasoocclusive coils
WO2007121405A2 (en) 2006-04-17 2007-10-25 Micro Therapeutics, Inc. System and method for mechanically positioning intravascular implants
KR20090018962A (en) * 2006-06-15 2009-02-24 마이크로벤션, 인코포레이티드 Embolization device constructed from expansible polymer
JP2010536491A (en) 2007-08-17 2010-12-02 ミクラス エンドバスキュラー コーポレイション Twisted primary coil for vascular treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8715312B2 (en) * 2001-07-20 2014-05-06 Microvention, Inc. Aneurysm treatment device and method of use
KR20100107255A (en) * 2009-03-25 2010-10-05 주식회사 엠비메디텍 Detachable coil with helical shape which make complex-shaped coil basket easily used in endovascular treatment of cerebral aneurysms

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5649949A (en) 1996-03-14 1997-07-22 Target Therapeutics, Inc. Variable cross-section conical vasoocclusive coils
WO2007121405A2 (en) 2006-04-17 2007-10-25 Micro Therapeutics, Inc. System and method for mechanically positioning intravascular implants
KR20090018962A (en) * 2006-06-15 2009-02-24 마이크로벤션, 인코포레이티드 Embolization device constructed from expansible polymer
JP2010536491A (en) 2007-08-17 2010-12-02 ミクラス エンドバスキュラー コーポレイション Twisted primary coil for vascular treatment

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WO2012091212A1 (en) 2012-07-05
KR20120073813A (en) 2012-07-05

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