KR100898903B1 - Carbon nanotube based brachytherapy device - Google Patents

Abstract

A carbon nanotube-based brachytherapy apparatus is disclosed that inserts a carbon nanotube-based small x-ray source into a desired site of a patient and treats the same. Carbon nanotube-based small X-ray sources generate X-rays and provide them to the affected area of the patient. The power supply unit supplies operating power to the carbon nanotube-based small X-ray source. The cooling unit cools the heat generated by the carbon nanotube-based small X-ray source. The controller controls the operation of the carbon nanotube-based small X-ray source, the power supply, and the cooling unit, and measures the appropriate amount of radiation dose required for treatment of the patient in real time.

Carbon Nanotubes, Treatment Devices

Description

Carbon nanotube based brachytherapy apparatus

The present invention relates to a disease treatment apparatus, and more particularly, to a proximity treatment apparatus using a carbon nanotube-based small X-ray source.

Conventionally, a linear accelerator or a radio isotope such as Ir (192), Cs (137), or Pd (103) has been used as a method for treating tumors such as breast cancer. The former has a huge installation cost and a relatively large device, which limits its use. Indirect method of irradiation is performed by linear accelerator from the outside, rather than directly inserted into the affected part of the body. This is inferior to that of brachytherapy. In addition, the latter is a method commonly used in the United States, Europe, and Japan, and can provide high dose of radiation to increase the treatment efficiency of cancer, and can be inserted into the body. The treatment efficiency can be improved, but it is difficult to handle because the radiation source of high dose is continuously emitted until the moment the radiation source is installed in the brachytherapy device and inserted into the affected area to treat, and the user may be exposed to radiation. There are many difficulties in use, such as paying close attention to use. In addition, there is a disadvantage that the treatment time is gradually longer due to the decrease in the dose according to the half-life of the radiation source. Of course, the cost of synthesizing suitable radioisotopes for treatment is also not economical. Recently, Xoft of the United States developed a small x-ray source using tungsten filament, a conventional hot electron emission method, to replace the brachytherapy system using radioisotopes, and obtained a clinical trial to obtain FDA approval as a device for cancer treatment. It is known that it is progressing, but it is not known that it has been successfully commercialized so far. However, since this method also uses a filament using a conventional hot electron emission method with low electron emission efficiency, it is not a new method beyond the conventional limit.

An object of the present invention is to provide a carbon nanotube-based brachytherapy apparatus for treating by inserting a carbon nanotube-based small X-ray source into a desired area of a patient and treating the conventional problems as described above.

In order to achieve the above object, the carbon nanotube-based brachytherapy apparatus according to the present invention comprises a carbon nanotube-based small X-ray source for generating X-rays to provide to the affected part of the patient; A power supply unit supplying operation power to the carbon nanotube-based small X-ray source; A cooling unit for cooling heat generated by the carbon nanotube-based small X-ray source; And a controller for controlling the operation of the carbon nanotube-based small X-ray source, the power supply unit, and the cooling unit, and measuring an appropriate amount of radiation dose required for treatment of the patient in real time.

Preferably, the carbon nanotube based small X-ray source is a carbon nanotube for generating an electron beam; An X-ray target that generates the X-rays by colliding with the electron beam generated by the carbon nanotubes; And a case having the carbon nanotube embedded therein, wherein the power supply unit includes a high voltage cable terminal connected to the carbon nanotube-based small X-ray source and a cable electrically connecting the high voltage cable terminal to the controller. The cooling unit supports the carbon nanotube-based small X-ray source, provides a cooling water circulation space between the carbon nanotube-based small X-ray source, and the X-ray generated from the carbon nanotube-based small X-ray source. It includes an applicator to uniformly deliver the affected part. More preferably, the applicator has an oval or spherical shape, the controller comprises a body; A handle installed at a side of the main body; And a wheel installed at the bottom of the main body. Most preferably, the carbon nanotube-based brachytherapy apparatus is electrically connected to the controller, an optical sensor that illuminates the patient and collects reflected light to output image data, and is electrically connected to the controller. Controlling the operating power supplied to the carbon nanotube-based X-ray source, parameters required for treatment of the patient generated from the carbon nanotube-based X-ray source, information on the cooling unit, and corresponding data in real time from the optical sensor. The computer monitor further includes a computer monitor in which a user graphic interface program for displaying image data is embedded.

The present invention provides a method that can be used safely and conveniently without the risk of radiation exposure by general users who do not have a radiation knowledge compared to the conventional method, and furthermore the optimal radiation required for the treatment of cancer The dose administration and irradiation time can be strictly controlled and adjusted to provide the effect of increasing the efficiency of cancer treatment. Existing methods are expensive, complicated treatment methods, and treatment is performed in an environment where there is a risk of radiation exposure for both patients and therapists, while the present invention can provide a system at a more economical price and worry about radiation exposure. It can be treated without care, providing a comfortable environment for both patients and operators. Conventional methods have caused discomfort for both the patient and the operator due to the decrease in the radiation dose due to the half-life of the radioisotope, but the present invention is designed to easily replace the small X-ray source for the treatment of patients Since the optimal X-ray dose can be supplied in the shortest time, there is an effect that can overcome the difficulties that may occur to both the patient and the operator due to long-term treatment.

Hereinafter, a brachytherapy apparatus for treating cancer using a carbon nanotube-based small X-ray source according to an embodiment of the present invention will be described in detail with reference to the accompanying example drawings.

In the present invention, by using the principle of quantum mechanical field emission (electron emission), by producing a small radiation tube using carbon nanotube (carbon nanotube) is known to have the best performance as an electron emitter (breast cancer) In this study, we develop an implantable brachytherapy system for the treatment of cancers such as cervical cancer, and apply it to clinical practice. The present invention is believed to be able to provide a dose that is equal to or better than that provided by expensive radioisotopes currently used in the clinic mainly for the treatment of breast cancer and the like in the United States, Japan and Europe. The aim is to develop a system that enables the user to easily treat patients with a simple operation by developing a safe brachytherapy system without the risk of medical problems. In order to achieve this object, the present invention can be largely divided into three parts. First, high dose of radiation is required to improve the treatment efficiency of tumors such as breast cancer, but to obtain high dose of radiation, the radiation therapy device should be located near the affected area (close-up treatment concept). It is necessary to provide a high efficiency electron emitter that can be increased. Therefore, the present invention is characterized in that the carbon nanotubes are known to have a small size that can be inserted into the human body (breast) to increase the efficiency of brachytherapy and also have excellent electron beam generation efficiency. In particular, the carbon nanotube-based small X-ray source to be developed in the present invention has a characteristic of a consumable that can be replaced with a new one when used for a certain period of time, so that it can be manufactured at an economical cost. Secondly, it includes a power supply unit for supplying power to the X-ray source, equipped with a small X-ray source, and thirdly, a cooling unit, which is a cooling system for cooling heat generated by the X-ray, and fourthly, treatment of cancer. It includes a controller that measures in real time the appropriate dose of radiation dose or dose, and adjusts the system as a whole. The small X-ray source, power supply, and cooling units mentioned above are attached to a controller that simply acts as the main control system. The controller is designed to be mobile and compact.

1 is a schematic diagram showing a brachytherapy apparatus for treating diseases such as cancer using a carbon nanotube-based small X-ray source according to a first embodiment of the present invention.

Carbon nanotube-based proximity therapy device of the present invention is a carbon nanotube-based small X-ray source 100, power supply (1), cooling unit (6), controller (15), optical sensor (18), and a computer monitor ( 14).

The carbon nanotube-based small X-ray source 100 generates X-rays and provides them to the affected part of the patient.

FIG. 2 is a diagram illustrating a structure of a transmissive carbon nanotube-based X-ray source 100 as an example of the carbon nanotube-based small X-ray source 100 shown in FIG. 1.

The carbon nanotube based small X-ray source 100 includes a carbon nanotube 3, an X-ray target 4, and a case 7. The carbon nanotubes 3 generate an electron beam. The carbon nanotubes 3 may be adhered to a metal or silicon substrate as an electron emission source through various methods such as CVD, screen printing, and paste.

In order to generate high-efficiency X-rays, a material that generates high-efficiency electron beams must be used as a cathode emitter. In the present invention, X-rays of carbon nanotubes known to have the highest electron beam generation efficiency are known. Use as cathode.

Since carbon nanotubes emit electrons according to the field emission principle, they can generate high-efficiency electron beams with lower power drive than conventional tungsten filament cathodes, which can be developed as energy-saving systems. A dose of radiation comparable to the high dose of existing radioisotopes for cancer treatment is secured.

Carbon nanotubes can be grown on small sized substrates (e.g. mm or μm) and thus can be made compact, so that carbon nanotube-based X-ray sources can be inserted into the treatment area of cancer and treated. It is made compact.

The fabricated carbon nanotube-based small X-ray source can be used to measure dose and to obtain doses equivalent to or better than those of radioisotopes such as Ir (192), Cs (137), and Pd (103). The analysis derives the optimum tube current ( mA ) and tube voltage ( kVp ).

The support 8 serves to support the carbon nanotubes 3, which are electron emission sources, and may be made of an insulator such as ceramic or a metal such as SUS. The X-ray source 100 using the carbon nanotubes (3) in order to avoid the dose reduction of the X-ray source 100 that may be caused by long-term use in the treatment of cancer, the small X-ray source is a new consumable that can be replaced with a new It is manufactured in the form so that a uniform amount of radiation dose can be provided during treatment.

The X-ray target 4 collides with the electron beam generated by the carbon nanotubes 3 to generate the X-rays. When the carbon nanotube-based small X-ray source 100 is a transmission type as shown in FIG. 2, tungsten or molybdenum or tungsten + molybdenum having excellent X-ray generation efficiency may be coated on the Be window.

The shape of the X-ray target 4 in the embodiment of the present invention shown in Figures 1 and 2 shows the shape of the surface, but not only the shape of the silk surface, but any structure that can evenly radiate the radiation in the affected area It is also possible.

The case 7 houses the carbon nanotubes 3. The case 7 may maintain the pressure inside the X-ray source 100 to about 10 ⁻⁷ to 10 ⁻⁶ torr and may be manufactured to be compact in order to be inserted into the human body. In addition, it can be made of an insulating material, such as conductors or ceramics, such as metal, if made of insulating material such as ceramic so that the generated X-ray and tungsten Kovar (kovar) can be bonded.

The power supply 1 supplies operating power to the carbon nanotube-based small X-ray source 100.

The power supply unit 1 electrically connects the carbon nanotube-based small X-ray source 100 and the controller 15, and a high pressure from a high voltage power supply (not shown) mounted on the controller 15. It is a high-voltage cable that performs a function of providing a phosphorus operation power to the carbon nanotube-based small X-ray source 100. In addition, in order to measure and supplement the tube current and the tube voltage generated in the X-ray source 100 in real time, the power and data automatic acquisition system of the controller in the high voltage cable terminal (1) mounted on the elliptic type applicator (not shown) ).

The cooling unit 6 cools the heat generated by the carbon nanotube-based small X-ray source 100.

The cooling unit 6 supports the carbon nanotube-based small X-ray source 100. The cooling unit 6 provides a cooling water circulation space 102 between the carbon nanotube-based small X-ray source 100. The cooling unit 6 includes an applicator for uniformly transmitting the X-rays generated from the carbon nanotube-based small X-ray source to the affected part. The applicator has an oval shape. On top of the applicator, a cooling water inlet 3 and a cooling water outlet 4 are formed spaced apart from each other by a predetermined distance.

The insulator 2 is configured for high pressure insulation between the power supply 1 composed of the high voltage cable and the cooling portion 6 composed of the applicator, and uses a material having excellent insulation such as ceramic.

The controller 15 controls the operation of the carbon nanotube-based small X-ray source 100, the power supply unit 1 and the cooling unit 6, and in real time the appropriate amount of radiation dose required for the treatment of the patient Measure The controller 15 includes a body 104, a handle 17, and a wheel 16. The main body 104 includes various devices for operating the brachytherapy apparatus of the present invention, for example, hardware and software devices such as a high pressure power and a cooling water circulation system GPIB board. The handle 17 is installed on the side of the main body 105 so that the main body 105 can be conveniently moved. The wheel 16 is installed at the bottom of the main body 105 to allow the main body 105 to move.

The controller, the main control system for optimally and safely operating a carbon nanotube-based X-ray brachytherapy system, is a computer program-based data acquisition system (DAQ), high voltage power supply and coolant unit (not shown). It includes a structure that is equipped with a moving device such as the wheel 16 to the main body 104 to enable movement and all similar structures.

The controller 15 monitors all necessary parameters for treating a patient (eg, beam current ( mA ) and tube voltage ( kVp ) of x-rays, x-ray exposure time, etc.). It is possible to input on the screen of the X-ray source after the treatment is automatically turned off and the indication of the end of the treatment to inform the patient and the therapist through the display method such as alarm.

The optical sensor 18 is electrically connected to the controller 15, illuminates the patient and collects reflected light to output image data.

Computer monitor 14 is electrically connected to the controller 15 and the operating power supplied to the carbon nanotube based x-ray source 100, treatment of the patient arising from the carbon nanotube based x-ray source 100. A user graphic interface program which controls the tube current and tube voltage or radiation dose, information of the cooling unit 6, which are necessary parameters, and displays the corresponding data and the image data from the optical sensor in real time is embedded.

The wire line 19 connects the controller 15 and the optical sensor 18 and transmits the power and the collected image to the controller 15 to operate the optical sensor 18 to the computer monitor 14. By presenting to the user, the user can observe the inside of the patient's body.

Reference numeral 5 is a carbon nanotube-based small X-ray source 100 shows a virtually inserted shape for the treatment of cancer, etc. in the human body, as an example of the human body of the patient is shown the stomach or uterus. Reference numerals 12 and 13 denote cooling water pipes.

Reference numeral 20 shows an example of the site of the lesion in the human body that needs treatment, and the X-ray source of the endoscope type (or pencil method) moves precisely to the location of the lesion correctly determined by the controller 15 to irradiate the lesion. It is designed to heal.

3 is a view showing a carbon nanotube-based brachytherapy apparatus according to a second embodiment of the present invention.

In the carbon nanotube-based brachytherapy apparatus according to the second embodiment shown in FIG. 3, all components except for the applicator functioning as the cooling unit 306 are the same as those of the first embodiment shown in FIG. Detailed descriptions of the elements are omitted.

The cooling unit 306 supports the carbon nanotube-based small X-ray source 100. The cooling unit 306 provides a cooling water circulation space 102 between the carbon nanotube-based small X-ray source 100. The cooling unit 306 includes an applicator for uniformly transferring the X-rays generated from the carbon nanotube-based small X-ray source 100 to the affected part. The applicator has a spherical shape. Cooling water inlet 9 and cooling water outlet 10 are formed above the applicator and spaced apart from each other by a predetermined distance.

Reference numeral 5 is a carbon nanotube-based small X-ray source 100 shows a virtually inserted shape for the treatment of cancer, etc. in the human body, the breast is shown as an example of the human body of the patient.

The carbon nanotube-based small X-ray source 300 is inserted into the treatment area of the cancer control system included in the controller 15, which is the main adjustment system to generate an optimal X-ray source only at the time of treatment (not shown). Design to control from

In order to cool the heat generated when the carbon nanotube-based small X-ray source 100 is operated, a circulating cooling system is designed so that a coolant such as water, which is a coolant, can circulate through the X-ray source and a controller ( 15) designed to control.

Reference numeral 5 is a carbon nanotube-based small X-ray source 100 shows a shape that is virtually inserted for the treatment of cancer, etc. in the human body, as shown above as an example of the human body of the patient.

4 is a diagram showing the radiation dose distribution performance of the X-ray source compared to I (125) and Pd (103), which is currently applied to the clinical radioisotope for treating breast cancer. In the case of tube current ≥ 300 μA @ 40 kVp x-ray, it was reported that the treatment efficiency is equivalent to the radioisotope used in the clinic.

FIG. 5 shows anisotropy dose distribution performance of an X-ray source compared to Ir (192), which is currently applied clinically as a radioisotope for the treatment of breast cancer, when tube current ≥ 300 μA @ 40 kVp x-ray. In addition, it has been reported that the treatment efficiency is equivalent to the radioisotope used in the clinic.

FIG. 6 is a diagram showing total radiation dose (dose) measurement values of X-ray sources compared to Ir (192), which is currently applied in clinical practice as a radioisotope for treating breast cancer. As shown in FIG. 4, it was reported that the tube current ≥ 300 μA @ 50 kVp x-ray showed the same treatment efficiency as the radioisotope used in the clinic.

7 is a view showing the characteristics of the CNT electron emission source according to the present invention.

The carbon nanotubes 3 are carbon nanotubes grown by CVD on a metal substrate having a diameter of 5 mm, as shown in FIG. 5 used as an electron emission source in a small X-ray source using carbon nanotubes. Is showing.

In FIG. 7, reference numeral 5 denotes a current characteristic of the carbon nanotube electron emission source according to the present invention. In the embodiment of the X-ray source using the carbon nanotube, the carbon nanotube electron having a diameter of 5 mm is 5 mm. The current is measured using an emission source and the maximum value of the total current is 5 mA. If the X-ray source is produced by reducing the diameter of the carbon nanotube electron emission source to 2 mm for insertion into the human body, a current of up to about 800 ㎂ can be obtained. It is possible to provide an excellent dose of 300 ㎂ or more, which is equivalent to the isotope Ir (192).

Example

The carbon nanotube-based small X-ray source 100 is separated from the cooling unit 6 so that it can be easily replaced with a new source if necessary.

The carbon nanotube-based small X-ray source 100 is manufactured to be sized to be inserted into an area requiring treatment and is adjusted by the controller 15 to emit radiation from the X-ray source only at a time or period requiring treatment.

In order to facilitate coolant circulation to cool heat that may occur in the carbon nanotube-based small X-ray source 100, the cooling unit 6, which is a coolant circulation system, is included if necessary. For example, the flow rate (flow rate, etc.) can be controlled automatically by the controller 15.

All variables required for the treatment of the patient, such as the radiation dose and the operating time of the X-ray source, are automatically controlled and managed by the controller 6 so as to remain optimal.

In order to overcome the inconveniences of the expensive treatment cost and the large equipment, which will be associated with the use of the existing linear accelerator for cancer treatment, to provide the optimal radiation dose for the treatment of only the affected area do.

As described above, the present invention provides a treatment problem that may occur in using expensive radioisotopes such as Ir (192), Cs (137), and Pd (103), which have been used in the conventional treatment of cancer. It can be safely and conveniently used by simple users by avoiding the risk of exposure to radiation exposure and without the radiation expertise.

The present invention has a difficulty in using a high dose of radiation continuously generated from the moment of preparing a radioisotope to the end of the treatment by inserting the radioisotope in the treatment of cancer using the existing radioisotope, overcomes this The safety and convenience of use are provided by inserting a radiation source into the affected area and providing a system in which the appropriate amount of radiation is released only at the time of treatment.

Existing radioisotopes have a half-life, and the dose of radiation due to half-life decreases as the number or time of treatment decreases, so that the treatment time becomes longer each time. It provides a method and means that can be.

In order to replace the conventional radioisotope system, the small tungsten filament-based X-ray source applying the conventional hot electron emission method is currently being studied in Xoft of the United States, but since the electron electron emission method is used, the electron generation efficiency is inherently inefficient. It is very poor. The present invention is a structure that can solve the essential problem by using an electron beam source capable of generating a high efficiency electron beam.

A compact high efficiency brachytherapy system using carbon nanotubes according to the present invention as an electron emission source is composed of three main parts to maintain optimal performance. The three parts are, firstly, carbon nanotube-based small X-ray sources, which have the characteristics of consumables that can be replaced with new ones after a certain period of time and can be manufactured at economical cost. Secondly, there is a cooling unit, which is equipped with a small X-ray source and supplies power for the X-ray source, and also cools the heat generated by the X-ray source. Third, the appropriate amount of radiation dose or It includes controllers that measure the dose in real time, turn the X-ray source on and off, and control the circulation of coolants such as water. As such, the device according to the present invention can be supplied at a lower price than existing methods, tools, and systems, and can be used safely and conveniently by general users, and a new brachytherapy system that contributes to improving the treatment efficiency of cancer. Will speed up commercialization.

Although the present invention has been described as a specific preferred embodiment, the present invention is not limited to the above-described embodiments, and the present invention is not limited to the above-described embodiments without departing from the gist of the present invention as claimed in the claims. Anyone with a variety of variations will be possible.

For example, the power supply and cooling parts are harmless to the human body, have elasticity that can be easily bent or bent, and can include any method using a similar or equivalent method. In the embodiment of the present invention, the treatment efficiency of the brachytherapy method is excellent due to the nature of radiation in the treatment of cancer, the present patent only shows an example of a small endoscope type X-ray source that can be inserted into the body, but the scope of the invention is silk This small size, as well as any size, can be applied to both carbon nanotube-based x-ray brachytherapy devices that can increase the efficiency of cancer treatment. In the present invention, the electron beam generating source utilized as the X-ray source uses carbon nanotubes, but the scope of the patent includes not only carbon nanotubes but also all nanostructure materials capable of generating high-efficiency electron beams.

In the embodiment of the present invention, the field that can be applied to the brachytherapy apparatus using X-rays based on carbon nanotubes may be mainly applied to breast cancer, cervical cancer, gastric cancer, esophageal and bronchial cancers as a treatment field for various cancers. As well as the disease can be applied to the treatment of various cancers that can increase the efficiency of treatment by applying a brachytherapy device, and can be expanded to include all that apply to various diagnostic (diagnostic) field. Fields that can be used in the embodiments of the present invention are the application of small X-ray sources not only to the treatment of silk cancer, but also to medical diagnostics and industrial diagnostics, particularly nondestructive tests (NDT) using radioisotopes. It is possible to cover all similar applications. In addition, the size of the small X-ray source in the embodiment of the invention is largely several cm Can be made as small as a few mm and the shape can include any and all shapes, including shapes such as endoscopes.

The present invention relates to a radio brachytherapy system using a linear accelerator or a radioisotope such as Ir (192), Cs (137), or Pd (103), which has been used to treat cancers such as breast cancer. To compensate for the shortcomings, it can provide advantages that ordinary users who do not have radiation knowledge, such as doctors who treat patients, can safely use them without fear of radiation exposure that may occur when treating patients. The present invention relates to a carbon nanotube-based economical and safe small radiation brachytherapy system capable of generating X-rays by high-efficiency electron beams. The present invention has advantages that conventional methods do not provide in terms of treatment efficiency, performance and price. If the present invention is put to practical use as a technology at home and abroad, there is no economic and technical From the perspective of the socio-cultural perspective of solving the government's pursuit of creating a healthy life society through cancer treatment and protecting individual health, the ripple effect is expected to be very large. I think it will. In addition, it is expected to provide a breakthrough in the current cancer treatment technology.

1 is a schematic view showing a carbon nanotube-based brachytherapy apparatus according to a first embodiment of the present invention.

FIG. 2 illustrates a structure of a transmissive carbon nanotube-based X-ray source as an example of the carbon nanotube-based small X-ray source shown in FIG. 1.

3 is a view showing a carbon nanotube-based brachytherapy apparatus according to a second embodiment of the present invention.

4 is a diagram showing the radiation dose distribution performance of the carbon nanotube-based small X-ray source compared to I (125) and Pd (103), which is currently applied to the clinical radioisotope for treating breast cancer.

FIG. 5 is a diagram showing the anisotropic dose distribution performance of an X-ray source compared to Ir (192), which is currently applied to a clinical radioisotope for treating breast cancer.

Figure 6 is a view showing the total radiation dose (dose) measurement of the X-ray source compared to Ir (192) currently applied in clinical trials as a radioisotope for the treatment of breast cancer.

7 is a view showing the characteristics of the CNT electron emission source according to the present invention.

<Explanation of symbols for the main parts of the drawings>

1: cable 2: insulator

3: carbon nanotube 4: x-ray target

5: human body 6: cooling part

7: case 8: support

9: cooling water inlet 10: cooling water outlet

14: computer monitor 15: controller

16: wheel 17: handle

100: carbon nanotube x-ray source 102: cooling water circulation space

104: main body 302: cooling water circulation space

306: cooling section

Claims (8)

A carbon nanotube-based small X-ray source for generating X-rays and providing them to the affected area of the patient; A power supply unit supplying operation power to the carbon nanotube-based small X-ray source; A cooling unit for cooling heat generated by the carbon nanotube-based small X-ray source; And a controller for controlling the operation of the carbon nanotube-based small X-ray source, the power supply unit, and the cooling unit, and measuring in real time an appropriate amount of radiation dose required for treatment of the patient. The method of claim 1, wherein the carbon nanotube-based small X-ray source comprises: carbon nanotubes generating an electron beam; An X-ray target that generates the X-rays by colliding with the electron beam generated by the carbon nanotubes; And A proximity therapy device for treating diseases comprising the case containing the carbon nanotubes. The apparatus of claim 1, wherein the power supply unit comprises a high voltage cable terminal connected to the carbon nanotube-based small X-ray source, and a cable electrically connecting the high voltage cable terminal to the controller. The small X-ray source of claim 1, wherein the cooling unit supports the carbon nanotube-based small X-ray source, provides a cooling water circulation space between the carbon nanotube-based small X-ray source, and the carbon nanotube-based small X-ray source. A carbon nanotube-based brachytherapy apparatus comprising an applicator for uniformly delivering the X-rays generated from a source to the affected part. The device of claim 1, wherein the applicator has an elliptical or spherical shape. The apparatus of claim 1, wherein the controller comprises: a body; A handle installed at a side of the main body; And Carbon nanotube-based proximity therapy device comprising a wheel installed on the bottom of the body. The apparatus of claim 1, further comprising an optical sensor electrically connected to the controller, the optical sensor illuminating the patient and collecting reflected light to output image data. The method of claim 7, wherein the operating power supplied to the carbon nanotube-based X-ray source electrically connected to the controller, parameters for treating the patient generated from the carbon nanotube-based X-ray source, information about the cooling unit, are provided. A carbon nanotube-based brachytherapy apparatus further comprising a computer monitor having a built-in user graphical interface program for controlling and displaying corresponding data in real time and image data from the optical sensor.

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