KR100856842B1 - A Method for coating of silver nanoparticles on fiber surface and a sanitary napkin and a diaper prepared by using this method - Google Patents

Abstract

The present invention relates to a method for coating silver nanoparticles in a uniform size and dense form on the surface of a fiber in a simpler way without the use of reducing agents or expensive equipment and sanitary napkins and diaper products made therefrom. The method according to the present invention was able to coat the silver nanoparticles in a uniform size on the surface of the fiber at a low concentration of nM unit in a simpler and more economical way by using polyethylene glycol. Therefore, it can be effectively used as an antibacterial material for sanitary napkins, diapers and the like.

Silver Nanoparticles, Silane Compounds, Polyethyleneglycols, Coatings, Sanitary Napkins, Diapers

Description

A method for coating of silver nanoparticles on fiber surface and a sanitary napkin and a diaper prepared by using this method}

1 is a graph showing absorption spectra and surface charges of silver nanoparticles, respectively, of a silver (Ag) colloidal solution coated on a fiber surface according to an embodiment of the present invention.

FIG. 2 is a photograph and graph showing a size distribution histogram obtained from low and high magnification TEM images and TEM images of silver nanoparticles.

Figure 3 is a graph showing the growth inhibitory effect on the yeast of the silver nanoparticles coated on the fiber surface by an embodiment of the present invention.

Figure 4 is a graph showing the growth inhibition of E. coli. Of silver nanoparticles coated on the fiber surface by an embodiment of the present invention.

5 is a graph showing the growth inhibition of S. aureus of the silver nanoparticles coated on the fiber surface by an embodiment of the present invention.

Figure 6 is a graph showing the ESR spectrum at room temperature of the silver nanoparticles coated on the fiber surface by an embodiment of the present invention.

7 is a perspective view of a sanitary napkin or diaper coated with silver nanoparticles according to a second embodiment of the present invention.

8 is a cross-sectional view of FIG. 7.

* Description of the symbols for the main parts of the drawings *

1. Body 2. Surface Sheet

3 ... Suction pad 4 ... Back sheet

15 ... Silver Nanoparticles

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The present invention relates to a method for coating silver nanoparticles on the surface of the fiber and to sanitary napkins and diaper products made therefrom, and more particularly to the surface of the silver nanoparticles in a simpler way without the use of reducing agents or expensive devices. The present invention relates to a sanitary napkin and a diaper product which are manufactured to have an effect of antibacterial, sterilization, deodorization, etc. using the coating method in a uniform size and dense form.

The fiber surface coated by silver nanoparticles can be used as an antimicrobial material and thus has a wide range of applications. In order to coat the silver nanoparticles on the surface, a deposition method, an electrochemical method, a method using a reducing agent, and a coating method by adsorption are generally used.

Deposition (Gas Deposition) is a method of vaporizing a metal and coating it on a surface. In recent years, spherical nanoparticles are arranged in hexagonal form, silver is deposited, and nano-spherical particles are removed to form a constant nanoparticle pattern. Forming techniques have been reported (MCChen et al ., Phys. Rev. B , 1995, 51: 4507; CLHaynes et al ., Nano Lett ., 2003, 3: 939; TR Jensen et al., J. Phys. Chem. B , 2000, 104: 10549).

Electrochemical Deposition is a method of adsorbing metal ions on a surface to be treated and then applying a charge to reduce the electrochemical deposition. The method of electrochemically forming a silver film on a gold surface ( Science , 1999, 284: 138), Electrochemical formation of 2-20 nm thick silver nanoparticles using silver peroxide, lithium peroxide and acetonitrile solution on silicon surface (RMStiger et al ., Langmuir , 1999, 15: 790), and silver nitrate on cellulose acetate fibers A method of coating silver nanoparticles using a / acetone / water solution (WKSon et al ., Macrocro. Rapid Commun ., 2004, 25: 1632) and the like are known.

In the chemical reduction method, n-propyltrimethoxysilane is patterned on a glass surface, and the reducing agent is adsorbed on the glass surface, and then silver or gold salt is added to obtain a surface coated with silver or gold particles. CEMoran et al ., Adv. Mater ., 2003, 15: 804), and methods of forming silver nanoparticles by adsorbing silver salts on the surface of polyimide and linking them at a high temperature of 250 ° C. (Y.Li et al ., Applied Surface Science , 2004, 233: 299).

Generally, the coating method is a method of treating a surface with a thiol group or an amine group, and then adsorbing silver nanoparticles or gold nanoparticles to the surface and attaching the nanoparticles to the surface by using an electrostatic force. The silver particles are produced in solution using a reducing agent and then introduced to the glass surface using electrostatic adsorption (I. Pastoriza-Santos et al ., Pure Appl. Chem ., 2000, 72:83), amines Coating gold nanoparticles on surface-modified silica nanoparticles with groups or thiols (SLWestcott et al ., Langmuir , 1998, 14: 5396; T. Pham et al ., Langmuir , 2002, 18: 4915), and After treating poly 4-vinylpyridine to the solid surface, silver nanoparticles are adsorbed again and tungsten oxide (WO ₃ ) is re-coated to the particles (Z. Wang et al ., Adv. Mater ., 2003, 15 1285) is known.

However, in the case of the deposition method and the electrochemical method, it is not economical because additional expensive equipment is required for the production of silver nanoparticles, and in the case of the method using the reducing agent, the reducing agent additionally needs to be additionally treated and processed at a very high temperature. In the case of the coating method, there was a problem that the nanoparticles must be prepared and processed separately.

Therefore, there is an increasing need to develop a method for coating silver nanoparticles on a specific fiber surface with a uniform size in a simpler and more economical way.

In addition, in order to use silver in various fields that can control microorganisms, it is necessary to manufacture silver nanoparticles at low cost and to reveal the mechanism of antimicrobial effect. In addition, it is also important to improve the antimicrobial effect.

On the other hand, conventional disposable sanitary napkins and diapers have been overlooked for the growth of bacteria, the growth of bacteria, and the development of odor due to the rot of secretions. I have been inconvenient.

As a result of investigating the components of commercially available disposable sanitary napkins and diapers, it consists of a nonwoven fabric, a polyethylene film, and the like. 99% of the film material is chemical fibers and plastics such as polypropylene and polyethylene, and the absorbent material is a polymer called polymer absorber and has a water absorption rate of 1000 times. It is easy to misunderstand it as 'absorbent paper, cotton pulp' according to the material label.

In addition, conventional disposable sanitary napkins and diapers are used in the process of making the wood pulp in the process of making a fluorescent bleach (fluorescent brightener) is used is a carcinogenic substance. These substances will only affect the next generation, even in fine amounts. Not only this, it depends on the skin and constitution, but on average 2-3 days after wearing itching and rash occurs, there is a problem that odor occurs.

Accordingly, the technical problem to be achieved by the present invention is to provide a method for more easily and economically coating silver nanoparticles of uniform size and dense form on the surface of a fiber so as to improve its effectiveness and to be used as an antimicrobial material.

Furthermore, another technical problem of the present invention is to provide a fiber with improved antibacterial and bactericidal effect by applying a method of coating silver nanoparticles.

Furthermore, another technical problem of the present invention is to provide a sanitary napkin having an antimicrobial and bactericidal effect by applying a method of coating silver nanoparticles.

Furthermore, another technical problem of the present invention is to provide a sanitary napkin and a diaper having an antimicrobial and bactericidal effect by applying a method of coating silver nanoparticles.

The present inventors grafted polyethylene glycol to the surface of the fiber, and by controlling the reaction time, temperature, and the ratio of the solvent optimally, by developing a method for coating the surface of the silver nanoparticles in a uniform size and dense form on the surface of the fiber Completed.

That is, according to the first aspect of the present invention,

Treating the silane compound on the fiber surface to introduce a reactor capable of bonding polyethylene glycol to the fiber surface;

Grafting the fiber surface with polyethylene glycol by treating the fiber surface with polyethylene glycol and a base catalyst; And

Forming silver nanoparticles on the surface of the grafted fiber polyethylene glycol is provided a method for coating the surface of the silver nanoparticles comprising a.

Further, according to the second aspect of the present invention,

Provided is a fiber coated with silver nanoparticles, characterized in that the silver formed by the method of nano-size by applying a method so that the sterilizing power of the silver can be added.

Furthermore, according to the third aspect of the present invention,

A surface sheet processed into a soft material and having a plurality of fine breathing holes formed on the surface thereof; A back sheet of film material sealed through the outer circumferential edge of the surface sheet; And a suction pad embedded between the back sheet and the surface sheet to absorb menstrual blood.

A sanitary napkin coated with silver nanoparticles is provided by applying silver formed in a nano size to the surface sheet by a method to configure the sterilizing power of the silver to the sanitary napkin.

Furthermore, according to the fourth aspect of the present invention,

A surface sheet processed into a soft material and having a plurality of fine breathing holes formed on the surface thereof; A back sheet of film material sealed through the outer circumferential edge of the surface sheet; And a suction pad embedded between the back sheet and the surface sheet to absorb the excrement.

There is provided a diaper coated with silver nanoparticles, characterized in that the sterilizing power of silver is applied to the diaper by applying silver formed in a nano size to the surface sheet by a method.

Hereinafter, terms used in the configuration of the present invention will be defined.

"Fiber" of the present invention includes all natural fibers, artificial fibers, inorganic fibers, organic fibers, synthetic fibers and the like.

The "microorganism" of the present invention is a microorganism that is usually 0.1 mm or less invisible to the naked eye and classified into bacteria, filamentous fungi, actinomycetes, yeast, etc. In particular, the present invention includes pathogenic microorganisms that cause diseases of animals and plants and animals.

"Antibacterial activity" of the present invention refers to the action of killing or inhibiting the growth of microorganisms.

The "nanoparticle" of the present invention refers to a particle having a size of a material in nanometers (length divided by 1 billion by 1 meter), the silver nanoparticles of the present invention can expand the contact area with microorganisms, Easily coated on the surface of the back can exhibit the antimicrobial activity.

In addition, the particle diameter of the "silver nanoparticle" of the present invention is preferably in the range of 3-100 nm, preferably in the range of 6-50 nm.

The coating method will be described in detail step by step based on the above terms.

The method of coating the silver nanoparticles according to the present invention on the surface of the fiber is characterized in that it comprises the step of introducing a reactor that can be bonded polyethylene glycol on the surface by treating the silane compound on the surface of the fiber.

This step is then a pretreatment step for effectively grafting polyethylene glycol (polyethylenglycol) on the fiber surface, wherein the available fibers may include both synthetic fibers and natural fibers.

When the fiber surface is pretreated with a silane compound, silanol groups (Si-OH) are formed on the surface, and condensation with Si-Me (or OEt) present in the silane compound occurs, resulting in Si (glass) -O. -Si-R bond is generated. By this reaction, a silane layer of a self assembled monolayer or a self assembled multilayer is formed on the fiber surface, and another material may be introduced into the functional group “R”.

The silane compound is 3-glycidoxypropyl trimethoxysilane, 3-chloropropyl trimethoxysilane and 3-isocyanatopropyl triethoxysilane (3-glycidoxypropyl trimethoxysilane). isocyanatopropyl triethoxysilane) is preferably any one selected from the group consisting of, but is not limited thereto.

After treating the silane compound, the reaction is preferably performed at 20 to 50 ° C. for 1 to 24 hours.

In the present invention, the silane compound may be used by dissolving in a solvent such as chloroform, ethanol, methanol, n-hexane, toluene, and specifically, may be prepared by using a silane compound solution of 1-5%.

In this case, in the case of synthetic fibers, it is preferable to perform a step of removing all the oxidizing gas adsorbed on the surface. In other words, the step of introducing a reactor capable of bonding polyethylene glycol to the surface by treating the silane compound on the surface of the fiber as described above after the step of injecting nitrogen to the synthetic fiber O ₃ or O ₂ plasma It is preferable to carry out.

Subsequently, the process according to the invention is characterized in that the fiber surface is treated with polyethylene glycol (PEG) and a base catalyst on which the reactor is introduced, thereby grafting the fiber surface with polyethylene glycol.

This step is a pretreatment step for attaching the silver nanoparticles to the fiber surface. In the above, polyethylene glycol has a molecular weight of 200 to 20000, and most preferably, a hydroxyl group (hydroxy; -OH) or an amine group (amine; -NH ₂ ) is present at the terminal. In the above treatment of the base catalyst with polyethylene glycol, the reactor on the fiber surface is opened by the base catalyst, polyethylene glycol may be introduced. The base catalyst is preferably 4-dimethylaminopyridine, but is not limited thereto. In order to effectively react in the above, and to sufficiently adhere the polyethylene glycol to the surface, it is preferable to react the PEG and the base catalyst at 50 to 100 ° C. for 6 to 48 hours.

Then, the method according to the invention is characterized in that it comprises the step of forming the silver nanoparticles on the surface of the fiber grafted polyethylene glycol. In order to form silver nanoparticles on the surface of the polyethylene glycol-grafted fiber, a solution of 0.1-5% (w / v) silver perchlorate (AgClO ₄ ) or 0.1-5% silver nitrate (AgNO ₃ ) is 25-80 ° C. It is preferable to treat for 0.5 to 48 hours at chloroform, and chloroform (hereinafter referred to as 'CHCl ₃ ') and tetrahydrofuran (hereinafter referred to as 'THF') as a solvent for the silver perchlorate and silver nitrate solution. It is preferable to use a solution mixed in a ratio (v / v) of 1: 1 or a solution in which THF and water are mixed in a ratio (v / v) of 1: 1. When treated with such a solvent type and mixing ratio, and reaction temperature and reaction time, silver nanoparticles can be coated on the fiber surface to be more uniform and dense.

As described above, the concentration of the silver nanoparticles coated on the surface of the fiber is low in the range of 0.1 nM to 33 nM, and the particle size of the silver nanoparticles is 3-100 nm, so that the surface of the fiber can be coated on a uniform size. This results in the effect of expanding the contact surface between silver nanoparticles and microorganisms, which in turn enhances the antimicrobial effect.

In particular, by applying the method of the present invention when applied to a sanitary napkin or diaper, not only can the sterilization and antibacterial effect be improved, but also by applying nanometer-sized silver particles to one surface directly contacting the skin of the sanitary napkin or diaper surface. It does not block the micropores in the surface sheet has the advantage that can be obtained together with the deodorizing effect.

Referring to FIGS. 7 and 8, which show typical concrete configurations of sanitary napkins or diapers, the main body 1 includes the edges of the surface sheet 2 and the surface sheet 2 in which a plurality of minute breathing holes are formed on the surface thereof. It is usually made of a back sheet (4) sealed and the adsorption pad (3) located between the back sheet (4) and the surface sheet (2) to absorb the menstrual blood.

In a conventional sanitary napkin or diaper having the above-described configuration, the surface sheet 2 and the back sheet 4 are a soft film, a liquid permeable nonwoven fabric, or a natural fiber in consideration of the fact that the surface sheet is in direct contact with the skin. (Cotton, etc.) is preferable, and in the case of the adsorption pad 3, it is common that the cotton in which the adsorbent is embedded is formed to have a predetermined thickness, and wrapped with a thin nonwoven fabric to maintain the shape of the cotton. You lose.

In addition, the bottom of the back sheet 4 to form a fixing layer (member) such as an adhesive, such as double-sided tape, or a Velcro member to be attached to the panties to be fixed.

In addition, the main body 1 may be made into a panty shape, and both ends of the upper end thereof may be fixed by forming an adhesive such as a double-sided tape or a fixing layer (member) such as a Velcro member.

On the other hand, as shown in Figures 7 and 8, the overall shape may be made of a wing shape so as to prevent the leakage of secretion as well as a straight, wherein the wings are one pair of left and right, as needed, two pairs, three pairs It is possible. It is also possible to wear a panty without a separate adhesive member.

By coating the silver nanoparticles having a nano-size according to the silver nanoparticle coating method of the present invention on one side of such a sanitary napkin or diaper, it is possible to provide a sanitary napkin or diaper which can maintain a more comfortable and clean state.

In this case, the nano size of the silver nanoparticles to be coated is not limited thereto, but is sufficient as the particle size within the range of 3 nm to 100 nm.

Hereinafter, the present invention will be described in detail by way of examples.

However, the following examples are merely to illustrate the invention, but the content of the present invention is not limited to the following examples.

Example  1: silver on the fiber surface ( Ag A) nanoparticle coating

1-1. Epoxy Group Introduction and Grafting on Fiber Surface

end. Polyester (synthetic fiber):

The polyester fibers were incubated in O ₃ (or O ₂ plasma) for 50 seconds and then blown with nitrogen for 10 minutes to remove all of the oxidizing gas adsorbed on the surface. Here, 1% 3-glycidoxypropyl trimethoxysilane (GPTS) / ethanol solution was treated at 50 ° C. for 12 hours to introduce an epoxy group to the surface of the polyester fiber, and washed three times or more with ethanol, followed by vacuum drying. And stored in a desiccator.

Polyethylene glycol 2000 (PEG2000-OH) having a molecular weight of 5% on the surface of the polyester introduced with the epoxy group is 2000, -OH group and 1% of 4-dimethylaminopyridine (DMAP) / t The butanol solution was treated at 50 ° C. for 24 hours to grafte PEG on the fiber surface.

I. Cellulose (natural fiber):

Without further treatment, 1% 3-glycidoxypropyltrimethoxysilane (GPTS) / ethanol solution was treated for 12 hours at 50 ° C, or 1% epichlorohydrine and 2% aqueous sodium hydroxide solution at room temperature. Time treatment was performed to introduce an epoxy group to the surface of the cellulose fiber. After washing three times or more with ethanol and vacuum dried and stored in a desiccator.

Polyethylene glycol 2000 (PEG2000-OH) having a molecular weight of 5% on the surface of the polyester introduced with the epoxy group is 2000, -OH group and 1% of 4-dimethylaminopyridine (DMAP) / t The butanol solution was treated at 50 ° C. for 24 hours to grafte PEG on the fiber surface.

1-2. Formation of Uniform Silver Nanoparticles on PEG-grafted Surfaces

The PEG grafted fiber surface was treated with 0.5% silver perchlorate (AgClO ₄ ) solution (using a solution containing 25 mL of CHCl ₃ and THF (1: 1) (v / v) as a solvent). Soak it for a while. The reaction was performed at room temperature where light was blocked, and the finished fiber surface was washed three times with THF, CHCl _{3 and} EtOH, and then dried with nitrogen.

Experimental Example  1: Proven antibacterial effect

< Formation of Silver Nanoparticles>

In order to investigate the anti-mildew effect of silver nanoparticles, silver nanoparticles in aqueous solution were prepared and used in the experiment.

To prepare silver nanoparticles in aqueous solution, 100 ml of 1.0 × 10 ⁻³ M silver nitrate solution was mixed with 300 ml of 2.0 × 10 ⁻³ M sodium borohydride aqueous solution.

Tertiary distilled water was used in the solution, and both solutions were cooled to ice temperature before mixing. By mixing the two solutions, the silver ions were reduced and combined with each other to form simple dispersed nanoparticles in transparent gel state in aqueous medium. The silver solution was yellow because of the absorbance of approximately 390 nm.

The silver solution was stirred repeatedly for about 1 hour until the dark color disappeared and stabilized. The silver nanoparticle solution was then stabilized and no color change occurred until several months.

Since the particle concentration of this solution is only 3.3 nM, it was concentrated 10 times using a rotary vacuum evaporator.

 This solution was then diluted to use samples of different concentrations as samples for anti-mildew effect experiments depending on the concentration of silver nanoparticles.

< Characteristics of the synthesized silver nanoparticles>

The aqueous solution of the prepared silver nanoparticles showed an absorption band at 391 nm, which is a typical absorption band (8) of spherical silver nanoparticles according to their surface plasmons. The stability of the concentrated solution was checked by observing its absorption spectrum after 10-fold re-dilution. The absorption spectrum of the re-diluted solution is almost identical to that of the original solution of the silver (Ag) nanoparticle solution (FIG. 1A).

This confirms that the silver nanoparticles do not additionally form dimers or aggregate with many particles, whereby when the silver nanoparticles form or aggregate, the local surface plasmons between two or more silver nanoparticles in contact with each other This is because no new absorption band was observed corresponding to the red side of the approximately 390 nm band.

To confirm that there were no silver nanoparticles in the solution, the solution was stirred with a zinc rod to completely precipitate and remove the silver nanoparticles to obtain an absorption spectrum of the remaining solution. This solution was then used as a control to confirm that other salts such as nitrates, borates and sodium ions contained in the silver (Ag) nanoparticle solution did not show antimicrobial activity during nanoparticle preparation.

The surface zeta potential of the silver nanoparticles was determined to be slightly negative (FIG. 1B). In the colloidal solution, the absorbed nitrate and boron ions are present on the surface of the silver nanoparticles, which causes the surface charges of the silver nanoparticles to be slightly negative.

The shape and size distribution of the synthesized silver nanoparticles were analyzed by TEM studies. A few drops of silver nanoparticle solution were dropped onto the TEM grid and the residue was removed with filter paper below the TEM grid.

The TEM images shown in FIG. 2A were obtained with high resolution TEM (JEOL, KE <-2000E7).

As shown in the shape and size distribution shown in FIG. 2B, the particles are very simple-dispersed with standard deviations of average diameters of 13.5 nm and 2.6 nm.

Proliferation inhibition test in yeast, E. coli and S. aureus.

Antimicrobial activity tests against yeast, E. coli and S. aureus were performed on MHA plates treated with silver nanoparticles at different concentrations (0.2 nM to 33 nM). Yeast was isolated from bovine mastitis.

That is, in order to determine the effect of inhibiting the growth of silver nanoparticles in yeast (isolated from bovine mastitis), E. coli 0157: H8 (ATCC 43886) and S. aureus (ATCC 19636), about 107 CFU of each microorganism was added to an MHA plate. Cultures were then sprinkled with 20 ml of silver nanoparticles in the middle of the MHA plate at a concentration ranging from 0.2 nM to 33 nM. Itraconazole (33 nM in yeast) and gentamycin (E.coli and S. aureus, 33 nM) were used as positive controls. Plates were incubated at 37 ° C. for 24 hours.

In addition, in order to evaluate the inhibition of proliferation of silver nanoparticles, after 24 hours of incubation, each plate was first analyzed by LAS3000 (FUJI, Japan), and the concentration (A) in the middle of the plate sprayed with silver nanoparticles in a common region and silver nanoparticles. The concentration (B) on the outside of the plate without particles was examined and the difference between A and B was measured and divided by the same area.

The average of three plate results for each sample was averaged and the results are summarized in FIGS.

Proliferation Inhibitory Effect of Silver Nanoparticles on Yeast, E. coli and S. aureus

Compared with the positive control itraconazole, 33 nM of silver nanoparticles showed similar growth inhibition in yeast, and a significant growth inhibition effect was observed at 13.2 nM (see FIG. 3).

Table 1 below shows the MIC results of the silver nanoparticles of the present invention.

division MIC of Silver Nanoparticles YEAST (ATCC19636) > 6.6 nM E.Coli (ATCC43890) > 3.3 nM St.aureus (Bovine mastitis) > 33 nM

As shown in the table, it can be seen that the minimum inhibitory concentration (MIC) for the yeast of the silver nanoparticles can be measured between 6.6 nM and 13.2 nM under this condition (see FIG. 4).

Specifically, in the case of E. coli, E. coli (ATCC 43890: O157: H7) known as a pathogen causing severe hemorrhagic enteritis was used in the present invention. In our results, silver nanoparticles were most effective against E. coli (FIG. 4 and Table 1).

The MIC of silver nanoparticles for E. coli can be measured between 3.3 nM and 6.6 nM, and growth inhibition was observed in proportion to concentration.

However, in the case of S. aureus (ATCC 19636), even when the concentration of silver nanoparticles is high, the growth inhibitory effect was insufficient, and showed no statistically significant inhibitory effect compared to the control group (gentamicin) under the same conditions (Fig. 5).

The MIC of silver nanoparticles against S. aureus was estimated to be 33 nM or more (Table 1).

In addition, the solution without silver nanoparticles used as a control did not show antimicrobial activity, suggesting that the antimicrobial activity is directly related to silver nanoparticles.

Gold nanoparticles (about 30 nM) were used as nano-sized metal controls to determine whether silver nanoparticles had anti-proliferative effects. Gold nanoparticles did not show any antiproliferative effect on various microorganisms under the same experimental conditions (see FIGS. 3 to 5).

Electron Spin Resonance (ESR) Study of Silver Nanoparticles

The mechanism of the growth inhibition effect of silver nanoparticles on microorganisms is not yet clear. One possibility is that proliferation inhibition may have been associated with free radical formation from the silver surface. Unregulated production of free radicals attacks membrane lipids and destroys membrane function (10). To confirm this possibility, the ESR spectra of the silver nanoparticles were analyzed.

The silver nanoparticles were aggregated by stirring the yellow colloidal solution with a zinc stick. Aggregation of silver colloidal particles was induced by stirring with zinc (Zn) rods without the addition of other additives to break the charge balance between the silver nanoparticles.

No other methods of inducing aggregation of silver nanoparticles, such as the addition of salts or chemicals, have been used to determine the exact effect of silver nanoparticles alone. The color of the solution turned dark brown by stirring the silver nanoparticle solution with a zinc rod, after which the aggregated silver nanoparticles slowly sank. Precipitated silver nanoparticles were collected as a powder and filled into glass microtubules.

The free radicals of the silver nanoparticles were recorded on an ESR spectrometer JES-TE 200 (JEOL, Japan) and the results are summarized in FIG. 6.

As shown in Figure 6, m1 and m2 represent the control peak of standard manganese (Mn), the middle peak (mT: 336.337) indicates the presence of free radicals liberated from silver nanoparticles, The peaks of the silver nanoparticles obtained are consistent with Danilczuk's et al. (19). This means that free radicals from silver nanoparticles are associated with antimicrobial activity.

<Antibacterial effect summary>

As a result, it was confirmed that the silver nanoparticles of the present invention showed antimicrobial activity even at nanomolar (nM) levels against yeast and E. coli (see FIGS. 3 and 4).

In addition, the inventors of the present invention determine that the antimicrobial mechanism of silver nanoparticles is that silver nanoparticles form free radicals and the free radicals cause membrane damage (see FIG. 6).

Example  2: sanitary napkin manufacturer

Based on the attached drawings 7 and 8 according to the method of the present invention was produced a sanitary napkin to which the silver nanoparticles (15) was applied, the specific process is as follows.

As shown in Figs. 7 and 8, in the main body 1 formed of a nonwoven fabric having a multi-layered structure, nanoparticles were prepared according to the method of Example 1 on the surface sheet 2 surface on which a plurality of fine breathable holes were formed on the surface thereof. The silver nanoparticles 15 having a size are uniformly coated, and the lower surface of the surface sheet 2 is formed with a suction pad 3 having an absorbent body having a predetermined thickness. It is formed in a state that is sealed with the edge of the back sheet 4 of the film material, it was manufactured to have a shape made of a form surrounding the suction pad (3) inside.

At this time, the back sheet 4 is made of a film material, the edge is sealed with the surface sheet is configured so that the adsorption pad (3) inserted therein is not separated, while the lower surface forms an adhesive layer such as double-sided tape It was made to be fixed to the panties.

The sanitary napkin of the present invention having the configuration as described above may be excellent in germicidal function by uniformly applying the silver nanoparticles (15) to suppress the reproductive power of harmful bacteria, fungi, athlete's foot, allergic bacteria and the like. As a result, not only the parasitic bacteria can be eradicated, but also the antibacterial function can be maintained to maintain a cleaner state.

Example  3: diaper manufacturer

Based on the attached drawings 7 and 8 according to the method of the present invention was produced a diaper to which the silver nanoparticles 15 are applied, the specific process is as follows.

As shown in Figs. 7 and 8, in the main body 1 formed of a nonwoven fabric having a multi-layered structure, nanoparticles were prepared according to the method of Example 1 on the surface sheet 2 surface on which a plurality of fine breathable holes were formed on the surface thereof. The silver nanoparticles 15 having a size are uniformly coated, and the lower surface of the surface sheet 2 is formed with a suction pad 3 having an absorbent body having a predetermined thickness. It is formed in a state that is sealed with the edge of the back sheet 4 of the film material, it was manufactured to have a shape made of a form surrounding the suction pad (3) inside.

At this time, the back sheet 4 is made of a film material, the edge is sealed with the surface sheet is configured so that the adsorption pad (3) inserted therein is not separated, while the lower surface forms an adhesive layer such as double-sided tape It was made to be fixed to the panties.

The diaper of the present invention having the configuration as described above can be excellent in the germicidal function by inhibiting the reproductive power of harmful bacteria, fungi, athlete's foot, allergic bacteria and the like by uniformly applying the silver nanoparticles (15). As a result, not only the parasitic bacteria can be eradicated, but also the antibacterial function can be maintained to maintain a cleaner state.

According to the present invention, by using polyethylene glycol it was possible to coat the silver nanoparticles in a uniform size on the surface of the fiber in a simpler and more economical manner and thus can be effectively used as an antimicrobial material.

In addition, sanitary napkins or diapers coated with silver nanoparticles according to the method of the present invention can prevent secondary infections due to excellent reproduction and fungal functions such as harmful bacteria, fungi, and allergic bacteria, and sweat secreted from the human body, It prevents the growth of bacteria propagated by wastes and sterilizes to prevent the occurrence of odors, and thus it is possible to maintain a clean state for a long time.

Claims (16)

Removing oxidizing gas adsorbed on the surface of the synthetic fiber; Treating the silane compound on the surface of the fiber to introduce a reactor capable of bonding polyethylene glycol to the surface of the fiber; Grafting the fiber surface with polyethylene glycol by treating the fiber surface with polyethylene glycol and a base catalyst; And Forming silver nanoparticles on the surface of the polyethylene grafted fiber; Method of coating a silver nanoparticles on the surface of the synthetic fiber, characterized in that made delete delete The method of claim 1, wherein removing the oxidizing gas from the surface of the synthetic fiber is performed by blowing nitrogen after exposing the O ₃ or O ₂ plasma. The method of claim 1, wherein the silane compound is any one selected from the group consisting of 3-glycidoxyoxy trimethoxysilane, 3-chloropropyl trimethoxysilane and 3-isocyanatopropyl triethoxysilane. And coating silver nanoparticles on the surface of the fiber. The method of claim 5, wherein the silane compound is treated at 20 to 50 ° C. for 1 to 24 hours. The method of claim 1, wherein the polyethylene glycol and the base catalyst is treated for 6 to 48 hours at 50 ~ 100 ℃ to coat the nanoparticles on the surface of the fiber. 8. The method of claim 7, wherein the polyethylene glycol has a molecular weight in the range of 200 to 20000, and a hydroxyl group or an amine group is present at the terminal thereof. 8. The method of claim 7, wherein the base catalyst is 4-dimethylaminopyridine. The method of claim 1, wherein the silver nanoparticles are formed by treating the polyethylene glycol-grafted fiber surface with 0.1-5% (w / v) silver perchlorate or silver nitrate solution at 25-80 ° C. for 0.5-48 hours. Coating silver nanoparticles on the surface of the fiber. The method of claim 1, wherein the particle diameter of the coated silver nanoparticles is in the range of 3 nm to 100 nm. The silver nanoparticles coated fiber, characterized in that configured to apply the silver sterilization power by applying the silver formed in the nano-size by the method of any one of claims 1, 4-11. delete delete delete delete

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