KR100852634B1 - Manufacturing apparatus and method for plastic ampoule - Google Patents

Abstract

The present invention relates to an apparatus for manufacturing a plastic ampoule and a method for manufacturing a plastic ampoule using the apparatus, wherein an ampoule having a uniform thickness of a neck portion is prepared while a single plastic ampoule is cut using polypropylene resin or polyethylene terephthalate. In addition, the purpose of the present invention is to obtain a plastic ampoule capable of high temperature sterilization at 121 ° C. for 20 minutes, and in order to achieve the above object, the present invention is molded in a state in which a blowing tube is located at the inlet of the ampoule. The present invention provides an apparatus and method for manufacturing a plastic ampoule in which the inlet portion of the ampoule is compressed and the body portion of the ampoule is blow molded by injecting the same pressure and amount of air into the blowing tube.

Description

Manufacturing apparatus of plastic ampoule and manufacturing method of plastic ampoule using same apparatus {Manufacturing apparatus and method for plastic ampoule}

1 is a schematic vertical cross-sectional view of a plastic ampoule manufacturing apparatus according to an embodiment of the present invention.

FIG. 2 is a vertical side cross-sectional view of the device shown in FIG. 1. FIG.

3A to 3E are views sequentially illustrating a manufacturing process of a plastic ampoule.

Figure 3a is a view showing a state in which the ferrisone expansion pin is inserted into the cylindrical ferrison,

Figure 3b is a view showing a state in which the ferrison is extended in a direction parallel to the mold,

Figure 3c is a view showing a state in which the blowing pipe is raised to the inlet of the ampoule imprinted in the mold,

3d is a view showing a state in which the inlet portion of the ampoule is compression molded and the body portion of the ampoule is blow molded by the blowing tube while the mold is closed,

3E is a view showing a molded product obtained by opening a mold.

4 shows a molding comprising a plurality of ampoules;                 

Figure 5 is a vertical vertical sectional view of the apparatus for producing a plastic ampoule according to another embodiment of the present invention.

6 is a view showing the shape of the ampoule filled with the chemical liquid

<Explanation of symbols for the main parts of the drawings>

10: mold

   11: ampoule shape

20: mold transfer part

   21: support plate 22: the first cylinder

30: ferry hand feeder

   31 housing 32 rod 33

   34: outer dice 35: adjustment screw 36: housing cover

40: ferry hand extension

   41: ferry extension pin 42: third cylinder

50: fourth cylinder

60: blowing part

   61: blowing pipe 62: the second cylinder

70: molding

   71: ferry hand 72: cutting line 73: cutting line 1

   74: air inlet 75: primary junction 76: second cutting line

   77: first deformation prevention part                 

80 neck

   81: chemical injection hole 82: second deformation preventing portion 83: secondary junction

   84: handle 85: bottleneck 86: handle projection

90: ampoule body

   91: deformation prevention irregularities

P: Perisone

The present invention relates to a device for manufacturing a plastic ampoule and a method for manufacturing a plastic ampoule using the device, more specifically, a plastic ampoule that can be cut and used individually as a high temperature sterilization at 121 ℃ 20 minutes as well as manufactured An apparatus for producing a plastic ampoule having a uniform thickness of each ampoule and a method for manufacturing a plastic ampoule using the apparatus.

Typically, the contents to be sealed and stored in a sterile state such as injection or oral solution are mainly stored using glass ampoules, but glass ampoules have a high possibility of being damaged during the storage and movement process.

In particular, the glass ampoule must cut the bottleneck in order to use the contents stored therein. In the process of cutting the bottleneck, the glass ampoule is injured by the glass fragments, or in the process of handling the cut glass ampoule. There are many problems.

In addition, in the process of cutting the bottleneck, the myriad of small glass fragments enter the ampoule, which is included in the contents, which may cause damage to the human body due to glass fragments during use.

Due to a problem with the glass ampoule, an ampoule made of plastic is used instead of the glass ampoule. The plastic ampoule is mainly manufactured using a low density polyethylene resin, and is manufactured through a conventional blow molding method. As such, when the plastic ampoule is manufactured through a blowing molding method, the production cost is significantly lower than that of the glass ampoule. When the plastic ampoule is used, the problem of the above-described glass ampoule can be effectively improved. . In particular, in the case of a plastic ampoule, if the mold is properly deformed, there is an advantage in that it is possible to manufacture an ampoule that can be cut and used individually.

However, the plastic ampoule manufactured by the conventional blow molding method has a disadvantage in that high temperature sterilization is impossible due to deformation of the ampoule during high temperature sterilization because of limited use of low density polyethylene resin which is easy to blow molding.

As a result, when storing and dispensing chemicals such as injections or oral solutions in plastic ampoules manufactured using low density polyethylene resin, the use period is significantly shortened compared to using glass ampoules, and high temperature sterilization is not performed. Therefore, there is a problem such as deterioration or contamination of the chemical liquid.

Attempts have been made to produce plastic ampoules using polypropylene (PP) resins or polyethylene terephthalate (PET) resins instead of low density polyethylene resins to enable high temperature sterilization. However, when the ampoule is manufactured by blow molding according to a conventional method using a polypropylene resin or a polyethylene terephthalate resin, there is a problem in that a thickness defect rate of the manufactured ampoule is very high. In particular, the neck thickness of the ampoule is non-uniform, it is not easy to cut the bottleneck of the prepared ampoule, there was a problem such that the deformation of the ampoule partially occurs at high temperature sterilization.

Due to the above disadvantages, the plastic ampoule is prepared using a low density polyethylene resin, but in the case of a liquid solution requiring high temperature sterilization, the glass ampoule is still used despite the problems with the glass ampoule.

Accordingly, the present invention is to solve the above-mentioned conventional problems, it is possible to obtain an ampoule with a uniform thickness of the neck, as well as to obtain a plastic ampoule that can be cut individually using polypropylene resin or polyethylene terephthalate as well as 121 ℃ It is an object of the present invention to provide a plastic ampoule manufacturing apparatus and a method for manufacturing a plastic ampoule using the apparatus to obtain a plastic ampoule capable of high-temperature sterilization at 20 minutes.

Another object of the present invention is to provide a plastic ampoule manufactured by applying the molding apparatus and method.

The present invention to achieve the above object                     

A mold in which a plurality of ampules that can be cut and used are imprinted individually; A mold transfer part attached to the mold to support the mold and a first cylinder integrally formed with the support plate, the mold transfer part configured to open and close the mold according to a moving direction of the first cylinder; A perison feeder for supplying perison to the mold; In the manufacturing apparatus of the plastic ampoule comprising: a blowing unit for supplying air to be in close contact with the shape of the ampoule imprinted on the mold after the mold is closed,

The blowing unit includes: a plurality of blowing tubes positioned at the inlet of each ampoule when the mold is closed to supply air at the same pressure; It provides a plastic ampoule manufacturing apparatus comprising a second cylinder for raising the blowing pipe to the inlet of each corresponding ampoule.

In addition, the present invention and the supply step of supplying the ferrison to the bottom of the mold; An ascending step of raising the plurality of blowing tubes by the second cylinder to the inlet of the ampoule imprinted on the mold so that the blowing tubes are positioned at the inlet of each ampoule; While the mold is closed by the first cylinder while the blowing tube is located at the inlet of the ampoule, the same pressure and amount of air are injected into each blowing tube so that the inlet of the ampoule is compressed and the body of the ampoule is blow molded. Molding step; And a post-treatment step of opening the mold to obtain a molded ampoule and post-processing the obtained ampoule.

In another aspect, the present invention provides a plastic ampoule characterized in that the production method.                     

Hereinafter, the present invention will be described in more detail with reference to the accompanying drawings, which are presented to aid the understanding of the present invention, but the present invention is not limited thereto.

The apparatus for manufacturing the ampoule of the polypropylene material or the polyethylene terephthalate material according to the present invention can be divided into two types of ampoule manufacturing apparatus according to the form of the perison supplied from the perison supply.

First, look at the manufacturing apparatus of the ampoule in the case of supplying the cylindrical ferrison to the mold from the ferrison feeder. 1 is a schematic vertical cross sectional view of a device for manufacturing a plastic ampoule according to an embodiment of the present invention, and FIG. 2 is a vertical side cross sectional view of the device shown in FIG.

As shown, the mold 10 according to the present invention is imprinted in the shape of the ampoule, the shape of the ampoule 11 is to be cut and used separately after molding. When the ampoule is formed, the periphery (P) is in close contact with the mold 10 in the blowing process, and the ampoule is molded into the ampoule shape 11 stamped on the mold. Each ampoule can be divided into an ampoule body in which the liquid is embedded and an inlet for injecting the liquid, and a detailed structure of the ampoule will be described later.

The mold 10 is attached to and supported by the support plate 21 of the mold transfer unit 20, and the mold transfer unit 20 is the support plate 21 and the first cylinder 22 integrally formed with the support plate 21. ). Therefore, the mold 10 is moved in accordance with the moving direction of the first cylinder 22, so that the mold 10 can be opened and closed.                     

The periphery feeder 30 is formed on the upper portion of the mold 10, and a cylindrical ferrison P is appropriately supplied to the mold 10 through the perison feeder 30.

According to the present invention, the ferrison expansion pin 41 for extending the cylindrical ferrison P supplied to the mold 10 in a direction parallel to the mold 10, and the ferrison expansion pin 41 to mold The ferry hand extension part 40 is provided which has the 3rd cylinder 42 which conveys in parallel with (10). The periphery extension pin 41 is transferred in a direction parallel to the mold 10 by the third cylinder 42 so that the cylindrical ferrison P is extended in a direction parallel to the mold 10. At this time, in the present invention, a fourth cylinder 50 for raising the periphery extension 40 is formed so that the perione expansion pin 41 can be inserted into the perione P.

Blowing part 60 according to the present invention is a mold (10) so that only the inlet portion of the ampoule after the mold 10 is closed at the same time while supplying air to the respective ampoules at the same pressure in the mold 10 is closed And a plurality of blowing tubes 61 formed to correspond to the number of ampoules engraved in Fig. 2) and a second cylinder 62 which raises the blowing tubes 61 to the inlets of the corresponding ampoules.

A method of manufacturing an ampoule using the apparatus for manufacturing an ampoule having the above configuration will be described in detail with reference to the accompanying drawings.

3A to 3E are views sequentially illustrating a plastic ampoule manufacturing process.

First, in the present invention, a cylindrical ferrison (P) as shown in Figure 2 is subjected to a supply step of supplying to the bottom of the mold (10).

After the cylindrical ferrison P is supplied to the lower end of the mold 10, the fourth cylinder 50 raises the ferry extender 40 so that the ferry extender 41 has the cylindrical ferrison. (P) is subjected to the insertion step to be inserted inside (Fig. 3a).

When the ferrisone expansion pin 41 is inserted into the perisone P, the ferrisone expansion pin 41 is moved in a direction parallel to the mold 10 by the third cylinder 42 to move the perisone P. The expansion step is extended in a direction parallel to the mold 10 (Fig. 3b). Through the expansion step, the ferricone P is uniformly expanded throughout the mold 10 so that the plurality of ampoule bodies have a uniform thickness so that the quality of each ampoule is uniform.

At the same time as the expansion of the perison P is completed, a plurality of blowing tubes 61 are lifted up to the inlet of the ampoules imprinted on the mold 10 by the second cylinder 62 and the blowing tubes 61 at the inlet of each ampoule. It goes through an ascending step to locate it (Fig. 3c).

When the raising of the blowing tube 61 is completed, the same pressure and amount are applied to each blowing tube 61 while closing the mold 10 by the first cylinder 22 while the blowing tube 61 is located at the inlet of the ampoule. The inlet of the ampoule is compressed and the main body of the ampoule is blow molded by injecting air. At this time, the ferry extension pin 41 of the ferry extension portion 40 is lowered (FIG. 3D).

As described above, if only the inlet portion of the ampoule is compression molded while the blowing tube 61 is located at the inlet of the ampoule, the thickness variation of the neck portion of the ampoule is minimized. In particular, the present invention is to compression molding only the neck of the ampoule by the blowing tube 61 in order to prevent the occurrence of defects due to the crack caused by the deviation of the thickness during high temperature sterilization and to manage a certain dimensional tolerance It was. Since only the inlet portion of the ampoule can obtain a compression molded effect, the inlet portion of the ampoule can be uniform in thickness, thereby making it possible to manufacture an ampoule having a uniform thickness as a whole.

When the molding is completed, the mold 10 is opened through the first cylinder 22 to obtain a molding 70 (FIG. 3E), and undergoes a post-treatment step of post-processing the obtained molding 70. At this time, the post-treatment step includes a conventional cooling, evacuation, liquid injection, sealing treatment and high temperature sterilization at 121 ℃ 20 minutes.

4 is a view showing a molding including a plurality of ampoules, a cut line 72 formed to be cut individually between the ampoules as shown; It consists of a ferry grip 71 comprising an air inlet 74 which is removed along the first cutting line 73 in use. That is, when the air inlet 74 and the ferry grip 71 are removed, each of the plurality of ampoules is cut individually and used. A more specific form of the ampoule will be described later.

FIG. 5 is a schematic vertical sectional view of a manufacturing apparatus of a plastic ampoule according to another embodiment of the present invention. As shown, the ferrisone feeder 30 forms a cylindrical ferricone sheet to form two sheet ferricones (P). ) Has a structure that can be supplied to the mold 10, and as the sheet ferricone (P) is supplied, the structure shown in Figure 1 does not include a periphery extension and the fourth cylinder.

In this case, in order to be able to supply two sheets of ferris (P) to the mold 10 by sheeting the cylindrical ferrison, the ferrison feeder 30 includes: a housing 31; A rod 32 for discharging the perisone in the housing 31; An inner die 33 and an outer die 34 for sheeting the cylindrical ferricone to supply two sheet ferricones P to the mold 10; An adjustment screw 35 formed on the outer die 34 for controlling the thickness of the sheet ferricone (P) to be extruded; And a housing cover 36.

As the sheet ferricone (P) is supplied to the mold 10 as described above, the manufacturing method is also simplified. That is, in the above-described steps of FIGS. 3A to 3E, the ascending step of raising the blowing tube 61 to the ampoule inlet imprinted on the mold 10 is performed without going through the steps of FIGS. 3A and 3B.

Specifically, the supply step of supplying two sheet ferricone (P) to the bottom of the mold 10 as shown in FIG. Ascending step of raising the plurality of blowing tubes 61 by the second cylinder 62 to the inlet of the ampoule imprinted on the mold 10 as shown in Figure 3c so that the blowing tube 61 is located at the inlet of each ampoule; ; As shown in FIG. 3D, the same pressure and amount of air are injected into each blowing tube 61 while the mold 10 is closed by the first cylinder 22 while the blowing tube 61 is located at the inlet of the ampoule. The inlet portion of the molding step so that the compression molding and the body portion of the ampoule blow molding; And a post-treatment step of opening the mold 10 to obtain a molded product 70 and post-processing the obtained molded product 70 as shown in FIG. 3E.

The molded article formed by the above method also has the form shown in FIG. 4, and as described above, when the ferry grip including the air inlet is removed along the first cutting line, each of the plurality of ampoules can be cut and used individually. Has a structure.

Referring to the figure of Figure 4 shown in more detail the shape of the ampoule as follows.                     

The form of the ampoule according to the present invention is heat-sealed to prevent foreign substances from entering the outside after removing the air inlet 74 and the ferry hand 71, and heat as a place to be removed along the second cutting line 76 during the injection of the chemical solution. A primary junction portion 75 having a first deformation preventing portion 77 formed thereon to prevent deformation of the ampoule when fused; The secondary joint portion 83 and the handle 84 having a chemical liquid injection hole 81 into which the chemical liquid is injected, and a second deformation preventing portion 82 formed to prevent deformation of the ampoules during thermal welding after being thermally fused after the chemical liquid is injected. Neck portion 80 and including; A bottleneck 85 formed to facilitate cutting of the neck portion 80; And an ampoule body 90 in which the chemical liquid is stored.

The ampoule having the above structure removes the primary junction portion 75, fills the contents through the chemical solution inlet 81, and seals the secondary junction portion 83 by heat fusion to produce an ampoule with a liquid solution. It becomes possible. The ampoule containing the liquid solution obtained in this way is used individually by twisting along the perforation line 72 when used individually, and twisting the handle 84 to extract the contents to cut off the bottle neck 85. 80) Remove and use liquid.

As described above, the present invention can be used to easily remove the neck portion 80 during use due to the formation of the bottleneck (85). That is, in order to take out the chemical liquid stored in the ampoule body 90, the handle 84 may be twisted by hand and then opened and then used.

In the present invention, a handle protrusion 86 is formed on the handle 84 for easier removal of the neck portion 80. In addition, in the present invention, in order to prevent deformation of the ampoule during high temperature sterilization (121 ° C./20 minutes or more), strain preventing recesses 91 are further formed on upper and lower portions of the ampoule body 90, respectively.                     

6 is a view showing the shape of the ampoule filled with the chemical liquid, after removing the primary junction from the ampoule shown in FIG. 4 and filling the contents through the chemical liquid inlet 81, the secondary junction 83 in a thermal fusion method Sealed to show the state of liquid.

The ampoule containing the liquid solution is used individually by twisting along the perforation line 72 when used as a single piece, and by removing the neck portion by cutting the bottle neck 85 by twisting the handle 84 to take out the contents. use.

As described above, the present invention can be produced using polypropylene or polyethylene terephthalate resin as a storage container for liquids that must be sealed and stored after high temperature sterilization (121 ° C./20 minutes or more), such as injection or internal medicine. Synthetic resin additives are not eluted at the time of sterilization and are harmless to the human body. Even if a large number of ampoules are produced at a time, the ampoules have a uniform thickness, so the packaging and storage are smooth.

In addition, it is designed as a bottleneck structure that can be easily cut and opened when using finished injection products. The ampoule has excellent transparency, permeability, and secured dimensional stability of the ampoule. It has a big effect on improving product reliability through securing the property.

Claims (11)

A mold in which a plurality of ampules that can be cut and used are imprinted individually; A mold transfer part attached to the mold to support the mold and a first cylinder integrally formed with the support plate, the mold transfer part configured to open and close the mold according to a moving direction of the first cylinder; A perison feeder for supplying perison to the mold; In the manufacturing apparatus of the plastic ampoule comprising: a blowing unit for supplying air to be in close contact with the shape of the ampoule imprinted on the mold after the mold is closed, The blowing unit includes: a plurality of blowing tubes positioned at the inlet of each ampoule when the mold is closed to supply air at the same pressure; And a second cylinder for raising the blowing pipe to the inlet of each corresponding ampoule. The method of claim 1, wherein the ferrison having a ferrisone expansion pin for extending the cylindrical ferrison supplied to the mold in a direction parallel to the mold, and a third cylinder for transporting the ferrisson expansion pin in a direction parallel to the mold. An extension; And a fourth cylinder which raises the periphery extension so that the periphery extension pin can be inserted into the perison. 4. The apparatus of claim 1, wherein the ferrison feeder comprises: a housing; A rod for discharging the ferricone in the housing; Sheet and cylindrical dies for feeding two ferricone sheets into a mold by sheeting a cylindrical ferison; A control screw formed on the outer dice to control the thickness of the extruded sheet; And a housing cover. A supplying step of supplying perison to the bottom of the mold; An ascending step of raising the plurality of blowing tubes by the second cylinder to the inlet of the ampoule imprinted on the mold so that the blowing tubes are positioned at the inlet of each ampoule; While the mold is closed by the first cylinder while the blowing tube is located at the inlet of the ampoule, the same pressure and amount of air are injected into each blowing tube so that the inlet of the ampoule is compressed and the body of the ampoule is blow molded. Molding step; And a post-treatment step of opening the mold to obtain a molded ampoule, and post-processing the obtained ampoule. The method of claim 4, wherein the supplying step of supplying the cylindrical ferrison to the bottom of the mold, and the ferrison expansion pin is raised through the fourth cylinder so that the ferrison expansion pin is inserted into the cylindrical ferrison; The method of manufacturing a plastic ampoule further comprising an expansion step of extending the ferrisone expansion pin inserted into the ferrisone in a direction parallel to the mold through the third cylinder. The method of claim 4, wherein the supplying step is a method for producing a plastic ampoule, characterized in that for supplying two sheet ferricone to the bottom of the mold. The method of claim 4, wherein the ferricone is made of polypropylene or polyethylene terephthalate. It is manufactured by the manufacturing method of any one of claims 4 to 6, and is heat-sealed to prevent the inflow of foreign matter after removal of the air inlet and perryon, and heat-sealed as the place to be removed along the second cutting line when injecting the chemical liquid A primary junction formed with a first deformation preventing part for preventing deformation of the ampoule; A neck portion including a second injection portion and a handle having a chemical liquid injection hole into which the chemical liquid is injected, a second deformation preventing portion that is thermally fused after the chemical liquid injection, and formed to prevent deformation of the ampoule during thermal welding; Bottlenecks formed to facilitate cutting of the neck; And an ampoule body in which the chemical liquid is stored. The plastic ampoule of claim 8, wherein a handle protrusion is formed on the handle. The plastic ampoule according to claim 8, wherein anti-deformation irregularities are formed on upper and lower portions of the ampoule body to prevent deformation of the ampoule during high temperature sterilization (121 ° C / 20 minutes or more). The plastic ampoule of claim 10, wherein the ampoule is made of polypropylene or polyethylene terephthalate resin.

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