KR100641300B1 - Blood glucose measurement apparatus and blood glucose measurement method using the same - Google Patents

Abstract

The present invention relates to a blood sugar measuring device and a blood sugar measuring method using the same, which can be easily checked according to the necessity of the blood sugar level of the diabetic, the characteristic configuration for this, and the case is fixed in a shape surrounding the blood vessel part of the body and ; A probe inserted into a blood vessel within a range in which at least two are insulated from each other in the case and do not interfere with blood flow; A measuring unit measuring a blood glucose level by an electrical resistance between the probes according to a control signal electrically connected to the probe in the case; And a transmitter / receiver for applying a control signal corresponding to the reception of a specific signal in the case to the measurement unit and transmitting a measurement signal corresponding to the reception of the measurement value of the measurement unit. According to this, the blood glucose measurement device is installed in the body to easily measure the blood glucose level whenever necessary without any trauma or stimulation of the body, and sends the blood glucose value to the insulin supply device to promptly supply insulin in response to changes in the body's blood sugar. It is effective in maintaining the health of diabetic patients.

Diabetes, Blood Glucose Measurements, Insulin, Blood Vessels, Probes, Resistance

Description

Glucose monitoring system and glucose monitoring method make using

Figure 1a is a graph for explaining the blood glucose level and the insulin secretion according to the normal person.

Figure 1b is a graph for explaining the blood glucose level and insulin secretion according to the example diabetes patients.

Figure 2a is a graph for explaining the blood sugar level control relationship according to the insulin supply device for the diabetic patient shown in Figure 1b.

Figure 2b is a graph for explaining the change in blood glucose level according to the change in the insulin dosage according to the insulin supply device and the health status of diabetic patients.

3 is a cross-sectional view schematically showing the configuration of a blood glucose measurement apparatus according to an embodiment of the present invention.

Figure 4 is a schematic cross-sectional view showing the configuration of a blood glucose measurement apparatus according to a modified embodiment of the present invention.

5 is a partially cutaway perspective view showing a modified embodiment of the probe constituting the present invention.

Explanation of symbols on the main parts of the drawings

10: blood glucose meter 12: case

14a, 14b, 14c, 14d, 14e, 14f: probe

18: transceiver 20a, 20b: sealing member

22: guide tube 24: clip

26: support ring 28: gap support

30: insulator

The present invention relates to a blood sugar measuring apparatus and a blood sugar measuring method using the same, and more particularly, to a blood sugar measuring apparatus and a blood sugar measuring method using the same, so that the blood sugar level of a diabetic patient can be easily identified as necessary.

In general, diabetes refers to a chronic disease in which the body does not absorb sugar due to lack of insulin secreted from the pancreas of the body or abnormal function of insulin secreted.

In Korea, the incidence of diabetes continues to increase, and about 2 million people, or 5.1% of the population, are estimated to be diabetics.

Diabetes can be divided into two types. One of them is insulin dependent diabetes mellitus, which often occurs before childhood or 30 years of age. This is a problem due to abnormal secretion of insulin and requires the supply of insulin from the outside. The other is insulin-independent diabetes, which usually occurs after age 40 and accounts for 80-90% of all diabetic patients. The latter diabetes is deeply linked to obesity, and even in this case, insulin supply is required.

Treatments for diabetic patients include diet to regulate food intake, exercise to reduce blood sugar by aerobic exercise to reduce blood sugar, and insulin supply to regulate blood sugar levels through forced insulin supply.

Here, the judgment of the supply of insulin to diabetics depends on the blood glucose measurement. The above-mentioned criteria for measuring blood glucose are hypoglycemic symptoms when the blood glucose level is 70 mg / dl or less after normal fasting at about 70-140 mg / dl. In addition, when the blood sugar level is more than 200mg / dl, the sugar appears to come out of the body through the urine, 400mg / dl raise the insulin supply is required.

Figure 1a shows a normal blood sugar level and the insulin secretion according to the normal person, Figure 1b is a graph showing the relationship between the blood sugar level and insulin secretion of diabetic patients.

With reference to these drawings will be described the insulin supply process for diabetic patients.

First, as shown in FIG. 1A, a normal person naturally regulates insulin secretion in response to an increase in blood sugar level by food intake, thereby maintaining a stable blood sugar level. On the contrary, diabetics have an abnormal secretion of insulin regardless of food intake, thereby gradually increasing blood glucose levels, as indicated by arrows H in FIG. 1B.

The insulin supply relationship according to the prior art for such a diabetic patient, as shown in Figure 2a, first has a process of continuously supplying a basic dose of insulin in the body of the diabetic patient using an insulin supply device. When the diabetic patient ingests food in the process of supplying the basic dose of insulin, the insulin supply device additionally administers insulin in response to the timing, thereby maintaining a stable blood sugar level.

However, the graph shown in FIG. 2A is an ideal expectation and has substantially the same problem as shown in FIG. 2B.

First, the insulin supply continuously supplies the basic dose of insulin, but when the diabetic patient performs exercise at a certain level in this process, as indicated by A1 in FIG. 2B, the metabolism is smoothly supplied to supply insulin. Even if blood glucose levels can be kept stable, or less than a basic dose of insulin may be sufficient. On the other hand, when the overdosage (X1) of the basic dose of insulin can be reversed to a relatively low glycemic condition, which has a problem that makes it difficult to control the blood sugar level of diabetic patients as well as waste of insulin.

In addition, the insulin supply device sets a meal time for the diabetic patient, and additionally supplies a certain amount of insulin corresponding to the time. However, the amount of meals of the diabetic patients is not constant, and the meal also has to be executed at a fixed time. In particular, as indicated by the A2 in Figure 2b, when diabetics skipped meals, even though the insulin does not require additional supply of insulin (X2) is a problem that is difficult to control the hypoglycemia and blood sugar level rather difficult Results in.

As described above, the insulin supply timing and dosage can be generally determined from the measurement of the blood glucose level that is changed by food intake, but the health status of the diabetic patient (eg, unit Rapid changes in exercise time, or rapid changes in body temperature due to the surrounding environment, and the supply of insulin in response to sudden changes in pulse rate due to unspecified reasons and changes in blood pressure due to complications). There are a lot of difficulties in measuring blood glucose for cases where needed.

In general, the blood glucose measurement method is performed through blood collection directly from the body, thereby causing physical stimulation, and it is difficult to measure blood glucose each time in response to changes in the state of health.

SUMMARY OF THE INVENTION The present invention has been made in view of the above-mentioned problem and necessity, and continuously measures blood glucose levels at regular intervals within a range that does not cause physical stimulation of diabetic patients. An object of the present invention is to provide a blood glucose measurement apparatus and a blood glucose measurement method for determining a timing.

Characteristic configuration of the blood glucose measurement apparatus according to the present invention for achieving the above object, the case is fixed in a shape surrounding a portion of the blood vessel in the body; A probe inserted into a blood vessel within a range in which at least two are insulated from each other in the case and do not interfere with blood flow; A measuring unit measuring a blood glucose level by an electrical resistance between the probes according to a control signal electrically connected to the probe in the case; And a transmitter / receiver for applying a control signal corresponding to the reception of a specific signal in the case to the measurement unit and transmitting a measurement signal corresponding to the reception of the measurement value of the measurement unit.

The case may include a first case proximate to a predetermined section of the blood vessel; By combining the blood vessel with the first case to fix the interior may be made of a second case for partitioning, or a material of a property of curing in a gel state, such as silicone, resin, GOE, alginate, synthetic resin, etc. It may be formed of. The transceiver may include Bluetooth having a condenser function.

On the other hand, the probe is a tubular first probe is inserted into the blood vessel in one direction; And a second probe inserted in a relative direction to the same vessel spaced apart from the site where the first probe is inserted, in a relative direction, wherein the first probe and the second probe outside the vessel induce a flow of blood through the vessel It can consist of interconnecting pipes. The configuration of the probe includes: a first probe having a first blood passage that guides the flow of blood through the blood vessel on the side wall in a tubular shape inserted into the blood vessel; It may be made of a second probe having a second blood passage for guiding the flow of blood through the blood vessel on the side wall in a tubular shape that is inserted into the same blood vessel spaced apart from the site where the first probe is inserted.

On the other hand, another installation configuration of the probe further includes a support ring which is inserted into the blood vessel and elastically expands the inner wall of the blood vessel so that there is a flow of blood, and a spaced support having a third blood passage therebetween and supported by the support ring. It may be composed of a third probe and a fourth probe disposed between the third blood passage of the gap support. In addition, another installation configuration of the probe may be composed of a fifth probe and a sixth probe that both ends are connected to each other by the insulator and inserted into the blood vessel to elastically expand the inner wall of the blood vessel so that blood flows.

In addition, it would be desirable to further include a sealing member for sealing the side wall portion of the vessel in which the probe is installed.

On the other hand, the blood glucose measurement method according to the present invention for achieving the above object is fixed to the shape surrounding the portion of the blood vessels in the body; A probe inserted into a blood vessel within a range in which at least two are insulated from each other in the case and do not interfere with blood flow; A measuring unit measuring a blood glucose level by an electrical resistance between the probes according to a control signal electrically connected to the probe in the case; And a transmitter / receiver for applying a control signal corresponding to the reception of a specific signal in the case and transmitting a data signal corresponding to the reception of the measured value signal by the measurement unit. Applying a control signal to the measurement unit in response to a specific signal; Measuring blood glucose in response to receiving the control signal; And transmitting a data signal in response to the measurement value signal reception from the measurement unit.

The applying of the control signal to the measuring unit may include: a first power applying step of applying power for measuring resistance between the probes; A second power supply step of applying a measurement value signal received by the measurement unit and the power required to transmit it to the outside of the body can be made.

Hereinafter, an embodiment of a blood sugar measuring apparatus and a blood sugar measuring method according to the present invention will be described with reference to the accompanying drawings.
3 is a cross-sectional view schematically showing the configuration of a blood glucose measurement apparatus according to an embodiment of the present invention.

In the blood glucose measurement apparatus 10 according to the preferred embodiment of the present invention, a case 12 having a shape surrounding a portion of blood vessels (B / V) in the body is fixed, and at least two of the case 12 are insulated from each other. And the probes 14a and 14b inserted into the blood vessel B / V within a range that does not interfere with the flow of blood through the blood vessel B / V. In addition, the case 12, the measuring unit 16 for measuring the blood glucose level by the electrical resistance value through the blood between the probes (14a, 14b) in accordance with a control signal that is electrically connected to the probes (14a, 14b) is provided. Equipped. In addition, the case 12 transmits and receives a control signal to the measurement unit 16 corresponding to the reception of a specific signal, and receives and transmits a measurement unit 16 for receiving measurement data of the measurement unit 16 and transmitting a corresponding measurement signal. It consists of a configuration including.

In the case 12 shown in FIG. 3, the first case 12a and the probes 14a and 14b corresponding to a predetermined section of the blood vessel B / V are inserted into the case 12 shown in FIG. 3. It may include a second case 12b which is partitioned to cover the blood vessel (B / V) portion to be maintained therein and maintains hermeticity therein and is fixed to the first case 12a. In addition, the edge portion of the area formed by the first and second cases 12a and 12b protects and secures the blood vessel B / V which is in contact with each other, and at the same time, the airtightness to the inside of the first and second cases 12a and 12b is secured. It may be further provided with a sealing member (20a, 20b) to maintain.

On the other hand, it is preferable that the material of the case 12 be harmless to a human body, but coating with a verified material on the surface of the case 12 of a material which has not been verified can be seen as the same technical idea. Of course.

The probes 14a and 14b consist of a tubular first probe 14a and a second probe 14b made of a conductor. The first probe 14a and the second probe 14b are respectively inserted into the single blood vessel B / V spaced apart from each other, and the first probe 14a and the second probe 14 are exposed from the blood vessel B / V. Each end of the probe (14b) may be configured to be interconnected to the induction pipe 22 to facilitate the flow of blood. To supplement this, the first probe 14a of the first probe 14a and the second probe 14b electrically connected to the measuring unit 16 may have a blood flow direction through the blood vessel B / V. The second probe 14b is inserted into the blood vessel B / V opposite to the blood vessel, and the second probe 14b is placed in the same blood vessel B / V spaced apart from the site where the first probe 14a is inserted along the direction of progress. Is inserted into the flow direction of the blood vessel (B / V) is formed by connecting to the induction pipe 22 for inducing the flow of blood to the end of the first and second probes (14a, 14b) protruding outward. At this time, prior to the installation of these probes (14a, 14b) to temporarily stop the flow of blood through the blood vessel (B / V) by means of a clip 24, etc. in a position out of the installation section of the case 12 It would be desirable to proceed with the installation. Another configuration for smoothing the flow of blood from the configuration of the first and second probes 14a and 14b is the first probe 14a on the sidewall of the first probe 14a inserted into the blood vessel B / V. A first blood passage (ha) is formed to guide the blood induced into the blood vessel back to the blood vessel (B / V). The second blood passage hb may be formed on the sidewall of the second needle 14b in the flow direction of the blood induced through the first blood passage ha and the blood vessel B / V adjacent thereto. .

Next, a preferred modified embodiment of the present invention will be described.
4 is a cross-sectional view schematically showing the configuration of a blood glucose measurement apparatus according to a modified embodiment of the present invention.

Blood glucose measurement apparatus 10 according to a modified embodiment of the present invention is fixed to the case 12 of the shape surrounding the blood vessels (B / V) in the body, the inside of the case 12 to the blood vessels (B / V) A third probe 14c and a fourth probe 14d to be inserted are provided. As described above, the case 12 includes a measuring unit 16 and a measuring unit 16 for measuring a blood glucose level using an electrical resistance value through blood between the third probe 14c and the fourth probe 14d. Transmitting and receiving unit 18 is applied to the control signal and transmit the measurement signal accordingly.
The case 12 according to another embodiment of the present invention illustrated in FIG. 4 includes a vessel including the installation portions of the third and fourth probes 14c and 14d and the measurement unit 16 and the transceiver unit 18 described above. B / V) may be made of a material that is cured in a gel state such as silicon, resin, GOE, alginate, synthetic resin, or the like.
The third and fourth probes 14c and 14d are first inserted between the support ring 26 and the support ring 26, which are inserted into the blood vessel B / V and elastically expand the inner wall of the blood vessel to allow blood flow. It is further provided with an interval support 28 having a blood passage hc and being supported. On the other hand, the third and fourth probes 14c and 14d made of a conductor are inserted into the blood vessels B / V along both sidewalls of the spacer support 28, respectively, so that the ends of these third and fourth probes 14c and 14d are inserted. May be arranged to face each other with the third blood passage hc of the mutually spaced support 28 interposed therebetween.

Next will be described the configuration of the probe according to another embodiment of the present invention.
5 is a partially cutaway perspective view showing a modified embodiment of the probe constituting the present invention.
Probe 14e, 14f of another embodiment shown in Figure 5, the one end and the side portion is connected to each other by the insulator 30 is inserted into the blood vessel (B / V) to elastically the blood vessel inner wall so that there is a flow of blood And a fifth probe 14e and a sixth probe 14f extending in a ring shape. At this time, the fifth and sixth probes 14e and 14f may measure blood glucose levels by measuring an electrical resistance of blood passing through the ring shape by the applied power.

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Meanwhile, the transmitter / receiver 18 constituting the blood glucose measurement apparatus 10 may be configured to include a Bluetooth having a condenser function and a controller for controlling each component including the control and the measurement unit 16 described above. have. In addition, the case 12 may be configured to further include a replaceable battery in a predetermined cycle, and may be configured to receive power by charging from an external specific means.

From the configuration of the blood glucose measurement apparatus 10 described above will be described the blood glucose measurement process for diabetic patients.

First, the blood glucose measurement apparatus 10 is derived from a surgical procedure installed in the body of a diabetic patient.

When the blood glucose measurement apparatus 10 is installed as described above, specific signals are transmitted at predetermined intervals through a separate communication means that communicates with the transceiver 18 in vitro, and the transceiver 18 that receives the specific signals is provided. ) Applies a control signal to the measurement unit 16 to measure the blood glucose level through the probes 14a, 14b, 14c, 14d, 14e, and 14f. In this case, the signal provided through the above-described communication means is used to provide power in place of the case where there is no battery installed in the case 12 and to supply the blood glucose data measured by the measurement unit 16 after the power supply. The supply may proceed to the second step.

On the other hand, the measuring unit 16 measures blood glucose in response to the reception of the control signal, and temporarily records this as data or applies the measured data to the transmitting / receiving unit 18 to transmit it to an external transmission means. It can be.

According to the present invention, the blood glucose measurement apparatus is installed in the body to easily measure the blood sugar level whenever necessary without any trauma or stimulation of the body, and transmits the blood sugar value to the insulin supply device to promptly supply insulin in response to changes in the blood sugar of the body. Has been made to maintain a stable health of diabetic patients.

Although the present invention has been described in detail only with respect to specific embodiments, it is apparent to those skilled in the art that the present invention may be modified or changed within the scope of the technical idea of the present invention, and such modifications or changes are claimed in the claims of the present invention. Will belong to the range.

Claims (11)

A case fixed in a shape surrounding a portion of the blood vessel in the body; A probe inserted into a blood vessel within a range in which at least two are insulated from each other in the case and do not interfere with blood flow; A measuring unit measuring a blood glucose level by an electrical resistance between the probes according to a control signal electrically connected to the probe in the case; And And a transmitter / receiver configured to apply a control signal corresponding to the reception of a specific signal in the case to the measurement unit and transmit a measurement signal corresponding to the reception of the measurement value of the measurement unit. The method of claim 1, The case may include a first case proximate to a predetermined section of the blood vessel; The blood glucose measurement apparatus, characterized in that consisting of a second case for partitioning the inside of the airtight by combining with the first case to fix the blood vessel. The method of claim 1, The case, the blood glucose measurement apparatus, characterized in that formed by curing in a gel state of any one or more combinations of silicone, resin, GOE, alginate, synthetic resin. The method of claim 1, The transmitting and receiving unit, the blood sugar measuring apparatus, characterized in that made of a configuration including a Bluetooth having a condenser function. The method of claim 1, The probe is a tubular first probe is inserted into the blood vessel in one direction; And a tubular second probe inserted in a relative direction to the same vessel spaced apart from the site where the first probe is inserted, in a relative direction, wherein the first probe and the second probe outside the vessel are blood flows through the blood vessel. The blood glucose measurement apparatus characterized in that the interconnection is made to the induction pipe so that. The method of claim 1, The probe has a first probe having a first blood passage for guiding the flow of blood through the blood vessel in the side wall in the shape of a tube inserted into the blood vessel; And a second probe having a second blood passage for guiding the flow of blood through the blood vessel on the side wall in a tubular shape inserted into the same blood vessel spaced apart from the site where the first probe is inserted. The blood sugar measuring device. The method of claim 1, The probe has a glucose measuring device comprising a fifth probe and a sixth probe that both ends are connected to each other by an insulator and inserted into the blood vessel to elastically expand the inner wall of the blood vessel so that blood flows. The method of claim 1, The probe further includes a support ring inserted into the blood vessel and elastically extending the inner wall of the blood vessel so as to allow blood flow, and a support spaced between the support ring and having a third blood passage, the spaced support being supported, and the third blood of the spaced support. The blood glucose measurement apparatus, characterized in that consisting of a third probe and a fourth probe disposed between the passage. The method according to any one of claims 1 to 8, The blood glucose measurement apparatus, characterized in that further comprising a sealing member for sealing the side wall of the vessel in which the probe is installed. A case fixed in a shape surrounding a portion of the blood vessel in the body; A probe inserted into a blood vessel within a range in which at least two are insulated from each other in the case and do not interfere with blood flow; A measuring unit measuring a blood glucose level by an electrical resistance between the probes according to a control signal electrically connected to the probe in the case; And a transmitting / receiving unit which applies a control signal corresponding to the reception of a specific signal in the case and transmits a data signal corresponding to the reception of the measured value signal by the measuring unit. Applying a control signal to the measurement unit in response to a specific signal received from the outside of the body; Measuring blood glucose in response to receiving the control signal; And And transmitting a data signal in response to receiving the measured value signal from the measuring unit. The method of claim 10, The step of applying a control signal to the measurement unit may include a first power supply step of applying power for measuring resistance between the probes; And a second power supply step of applying a power value required for receiving the measurement signal by the measuring unit and transmitting it to the outside of the body.

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