KR100505105B1 - Triple coated retinyl palmitate, ascorbic acid and cosmetic composition containing the same - Google Patents

Abstract

The present invention is a collagen, sodium carboxylate on the surface of a mixture (hereinafter referred to as "vitamin AC") that maintains the respective active ingredients by mixing independent retinyl palmitate (Vitamin A, Palmitate) and pure vitamin C (ascorbic acid) The present invention relates to a vitamin AC having a triple coating structure stabilized by sequentially coating methyl beta glucan and maltodextrin and a cosmetic composition containing the same.

The triple-coated vitamin AC has no content change even after sonication, and thus contains wrinkles and wrinkles when included in a conventional cosmetic composition containing a UV absorber and ethylenediaminetetraacetic acid and having an acidity (pH) of 3.5 to 5.0. Functional cosmetics with excellent skin whitening and antioxidant effects can be prepared.

Description

Triple coated retinyl palmitate, ascorbic acid and cosmetic composition containing the same}

The present invention is a collagen, sodium carboxylate on the surface of a mixture (hereinafter referred to as "vitamin AC") that maintains the respective active ingredients by mixing independent retinyl palmitate (Vitamin A, Palmitate) and pure vitamin C (ascorbic acid) The present invention relates to a vitamin AC having a triple coating structure stabilized by sequentially coating methyl beta glucan and maltodextrin and a cosmetic composition containing the same.

Human skin aging is caused by wrinkles, blemishes such as blemishes, vasodilation, wide pores and sagging skin. Among them, retinol and retinyl palmitate are well known and effective. Many skin external preparations are used as ingredients. For example, a cosmetic material using retinol as a collagen synthesis promoter (patent application 1996-40382), a white cosmetic material using a diester of aromatic carbonic acid such as benzoic acid as a whitening ingredient (patent application 1999-00232), retinol as an active ingredient Melanogenesis inhibitors (patent application 1998-19763).

Vitamin A is a retinol, dihydroretinol, retinyl ester, retinoic acid and vitamin A is a precursor of carotenoids, such as physiological activity in vivo. If you use the dual active retinic acid directly as a cosmetic, there are many disadvantages to the skin. Therefore, esterified substances such as retinyl palmitate, a derivative that can eliminate the side effects of the skin, are absorbed into the skin It is broken down by the agent and then metabolized via retinol to retinic acid for effect.

Retinol or retinol derivatives express mRNA from DNA, a cell nucleus in skin cells, thereby promoting cell differentiation and promoting the synthesis of collagen and elastin, which are intercellular tissues, and are added to cosmetics and external skin preparations as main ingredients. When it is used, it eliminates keratinization by promoting the division of epithelial cells, increases skin tissue density due to excellent collagen synthesis, increases the elasticity of skin, suppresses melanin production, and does not cause any disorder on the skin. It is also known as a cosmetic preparation for skin that plays an important role in immune function.

The pigments that determine human skin color include melanin, hemoglobin and carotenoids. The various colors of skin, hair and eyes are determined by these pigments. The most important pigment that determines color in skin is melanin, and the color of skin depends on the amount, nature and distribution of melanin. In humans, the pigments in the skin and hair protect against the harmful effects of sunlight (especially ultraviolet rays). For example, people with poor pigmentation (albino: ALBINO) are very sensitive to sunlight and are prone to burns.

Short wavelength ultraviolet rays (290-320 nm) and carcinogens remove oxygen radicals from the skin and protect the skin from damage. Therefore, high levels of melanin mean that it has an effective response system to protect the skin from physical and chemical toxic substances. Factors that promote the production of melanin include the above-mentioned sunlight (ultraviolet rays) as well as hormones such as estrogen, prostaglandin and bleomycin.

In the melanin production and disappearance cycle, the melanocytes of the skin are cleaved by sunlight (ultraviolet rays), tyrosinase is synthesized in the Golgi apparatus, and the melanin is formed after the Golgi body and the endoplasmic reticulum are combined to form melanin. The melanin is delivered to the skin cells and exhibits a circulating action in which the melanin is lost and extinguished together with the epidermal peeling. In addition, the melanin is a complex polymer made from dopaquinone, dopacrorom, indole-5, and 6-quinone produced by using tyrosinase, a kind of amino acid, in the melanosome. This melanin production mechanism may be characterized by a reaction involving only one enzyme, tyrosinase, and expects a whitening effect by inhibiting the tyrosinase activity and preventing melanin production.

In the whitening cosmetics, the method of inhibiting melanin production can be largely divided into the following methods.

Firstly, by first blocking the ultraviolet rays to remove the main cause of melanin production, this method can be expected to have good results by allowing the cosmetic composition to contain a light scattering agent or light blocking agent. Secondly, melanin production is inhibited by inhibiting the synthesis of core carbohydrate, which is required for tyrosinase to be active, such as glocosamine. Third, there is a method that interferes with the function of tyrosinase, the only enzyme involved in melanogenesis, such as koji acid or arbutin and pure vitamin C. In addition, the fourth method has a specific toxicity against melanocytes, which produce melanin, such as hydroquinone, thereby preventing cell division.

In this way, when retinyl palmitate and pure vitamin C are formulated into cosmetics, they simultaneously solve functional wrinkle improvement and whitening effects and have excellent antioxidant effects, but are easily oxidized by light, heat, air, moisture, etc. There is a disadvantage that it is difficult to commercialize the product.

In order to solve the above problems, the present inventors have mixed collagen and sodium on the surface of a mixture (vitamin AC) in which retinyl palmitate (Vitamin A, Palmitate) and pure vitamin C (ascorbic acid) were mixed to maintain respective active ingredients. After coating the carboxymethyl beta glucan and maltodextrin in turn, it was again contained in a cosmetic composition containing a UV absorber and ethylenediaminetetraacetic acid disodium, pH 3.5-5.0, the triple coated retinyl palmitate Since pure vitamin C is not oxidized, the skin wrinkle improvement effect and the whitening effect are excellent, and due to the synergistic antioxidant effect, the intrinsic content is not changed and no adverse effects are caused on the skin.

Accordingly, an object of the present invention is to provide a stable vitamin AC prepared by triple coating with collagen, sodium carboxymethyl beta glucan and maltodextrin.

Another object of the present invention is to provide a cosmetic composition prepared by incorporating the stabilized vitamin AC into a conventional cosmetic composition containing a UV absorber and ethylenediaminetetraacetic acid.

Another object of the present invention is to provide a triple coated vitamin AC which can be used for a long time in an unoxidized state by triple coating vitamin AC with collagen, sodium carboxymethyl betaglucan and maltodextrin.

Another object of the present invention, after coating the surface of the vitamin AC with collagen, sodium carboxymethyl beta glucan and maltodextrin triple, and then using a UV absorber and ethylenediaminetetraacetic acid or ethylenediaminetetraacetic acid disodium By including in the cosmetic composition containing a pH of 3.5 to 5.0, the triple-coated vitamin AC is not oxidized to improve wrinkles, skin lightening and antioxidant effects, there is no change in intrinsic content, does not cause side effects on the skin It is to provide a cosmetic composition containing vitamin AC.

Vitamin AC mixture having a triple coating structure of the present invention for achieving the above objects, first mixed with pure Ascorbic Acid and Retinyl palmitate, it is coated (included) with vegetable collagen (Phyto collagen), which is again Na-CM- Coated (included) with β-Glucan, and ascorbic acid + Retinyl palmitate + Phyto collagen + Na-CM-β-Glucan, secondly coated (included) by Na-CM-β-Glucan, finally coated with Malto dextrin ( Inclusion) provides a series of stabilized vitamin AC triple coated with collagen, sodium carboxymethyl betaglucan and maltodextrin. Vitamin AC mixture having a triple coating structure of the present invention, 15 to 20% by weight of collagen, 25 to 30% by weight of sodium carboxymethyl betaglucan and maltodextrin 35 with respect to 5 to 10% by weight of retinyl palmitate and pure vitamin C. It is characterized in that the -40% by weight is coated respectively.

The cosmetic composition containing the vitamin AC of the present invention is a triple cosmetically coated retinyl palmitate and pure water in a conventional cosmetic composition containing 0.01 to 1.0% by weight of a UV absorber and 0.005 to 0.05% by weight of ethylenediaminetetraacetic acid. It is characterized by containing 0.1 to 2% by weight of vitamin C, respectively.

The cream cosmetic composition containing the vitamin AC of the present invention also contains 2.00 g of hydrogenated castor oil, 3.00 g of lipophilic monostearate, 2.00 g of self-emulsifying monostearate, 3.00 g of stearic acid, 2.00 g of setanol. , 3.00 g of jojoba oil, 5.00 g of squalane, 8.00 g of caprylic capric triglyceride, 0.50 g of natural vitamin E acetate, 0.10 g of paraoxybenzoic acid propyl and 0.50 g of 2-hydroxy-4-methoxybenzophenone 1 mixture; Purified water was added to 5.00 g of glycerin, 0.50 g of disodicone 2,2-dihydroxy-4,4-dimethoxy-5,5-disulfobenzophenone, 0.10 g of allantoin, and 0.10 g of methyl paraoxybenzoate, adding 100 g of all A second solution was dissolved, the first mixture and the second mixture were added, stirred, emulsified and cooled, and then ethylenediaminetetraacetic acid disodium 0.02 was added to the sample mixed with the first mixture and the second mixture. g, retinyl palmitate 2.00g, pure vitamin C 2.00g, collagen 5.00g sodium carboxymethyl betaglucan 8.00g, maltodextrin 10.00g and flavorings were added, stirred and mixed to form a pH (pH) 4.0.

In addition, the lotion cosmetic composition containing the vitamin AC of the present invention, the hydrogenated castor oil 0.50g, lipophilic monostearic acid glycerol 1.00g, self-emulsifying monostearic acid glycerin 2.00g, stearic acid 1.00g, theta 0.50 g of knol, 5.00 g of caprylic capric triglyceride, 3.00 g of jojoba, 3.00 g of squalane, 0.50 g of vitamin E acetate, 0.10 g of paraoxybenzoic acid propyl and 0.30 g of 2-hydroxy-4-methoxy benzophenone A third mixture formed; 50 g of purified water was added to 5.00 g of glycerin, 0.10 g of carboxyvinyl polymo, 0.20 g of disodicone 2,2-dihydroxy-4,4-dimethoxy-5,5-disulfobenzophenone, and 0.10 g of methyl paraoxybenzoate. After forming a fourth melted mixture, the fourth mixture was added to the third mixture, stirred, emulsified and cooled, and then ethylenediaminetetraacetic acid was added to the sample in which the third mixture and the fourth mixture were mixed. Add sodium 0.02g, retinyl palmitate 0.50g, pure vitamin C 0.50g, collagen 1.25g, sodium carboxymethyl betaglucan 2.00g, maltodextrin 2.50g, flavor and purified water, and stir and mix so that the total weight is 100g (pH) characterized in that formed in 4.0.

The present invention includes a vitamin AC mixture, as described above, in a cream or lotion cosmetic composition containing a UV absorber in combination with ethylendiaminetetraacetic acid disodium after triple coating with collagen, sodium carboxymethyl betaglucan and maltodextrin. To prepare a cosmetic composition containing vitamin AC.

Subsequently, the cosmetic composition containing the triple coated vitamin AC and the cosmetic composition containing the normal retinyl palmitate and the pure vitamin C having no triple coating structure were irradiated with UV, respectively, and the degree of coloring was measured and sonicated. Next, the changes in the content of retinyl palmitate and pure vitamin C were analyzed. As a result, it was confirmed that the cosmetic composition containing the stable vitamin AC of the present invention is not only chemically stable, but also excellent in wrinkle improvement, skin whitening and antioxidant effects.

The present invention includes vitamin AC, which is triple coated with collagen, sodium carboxymethyl betaglucan and maltodextrin, in a conventional cream cosmetic composition containing an ultraviolet absorber and ethylenediaminetetraacetic acid.

Retinyl palmitate and pure vitamin C, which are effective ingredients of a cosmetic composition containing stable vitamin AC, are known as collagen synthesis materials.

As the raw materials used in the present invention, raw materials allowed by cosmetic regulations, that is, raw materials allowed according to the Korean Food and Drug Administration Notification No. 200-27 "Regulations on Designation of Cosmetic Raw Materials, Standards, Test Methods, etc." were used. A. Vitamin C (Ascorbic Acid); -Powder type pure Ascorbic Acid-Manufacturer: Roche (Swiss)-Raw material for cosmetics (import)-Code No. : C1844 B. Vitamin A Derivatives (Retinyl palmitate); -Liquid type 1,000,000 IU Retinyl palmitate-Manufacturer: Roche (Swiss)-Designation of cosmetic raw materials (based on cosmetic raw materials)-Code No. : 367C. Collagen (Phyto collagen) -Water-soluble liquid type vegetable collagen (Phyto collagen)-Manufacturer: Ichimaru Pharm (Unary pharmaceuticals)-Raw materials that can be used to manufacture cosmetics (import)-Code No. : C1577 D. Sodium Carboxy Beta Glucan (β-Glucan) -Na-CM-β-Glucan in water-soluble Liquid type-Manufacturer: Derma Lab-Cosmetic Toilet Fragance Association (CTFA)-CAS No. : 9050-36-6 E. Maltodextrin (Glucidex-11) -Malto dextrin of powder type-Manufacturer: Samyang Genex-CTFA (Cosmetic Toilet Fragance Association)-CAS No. : 160872-27-5 In the present invention, the weight ratio of each of the vitamin AC triple coated with collagen, sodium carboxymethyl betaglucan and maltodextrin is 5-10% by weight of retinyl palmitate and pure vitamin C, coated collagen 15 20 wt%, sodium carboxymethyl betaglucan 25-30 wt%, maltodextrin 35-40 wt%. These triple coated stable vitamin ACs are included in the total cosmetic composition of 0.1 to 2% by weight, respectively.

The cosmetic composition containing the triple-coated vitamin AC of the present invention can be applied to general skin poultices including lotions, creams, and the like, and these preparations are effective by using a stable retinyl palmitate and pure vitamin C by conventional methods. It can be formulated to contain as a component and used as an external preparation.

Although the ultraviolet absorber contained in the cosmetic composition of this invention may use what kind of thing, ethyl salicylate phenyl paraamino benzoate, 2-hydroxy-4- methoxy benzophenone, 2, 2- dihydroxy- 1, 1- dimethoxy Benzophenone, disodicone 2,2-dihydroxy-4,4-dimethoxy-5,5-disulfobenzophenone, etc. are suitable, These ultraviolet absorbers can be used individually or in combination of 2 or more.

The cosmetic composition by this invention can maintain stability at high temperature by making pH maintain 3.5-5.0. At this time, lactic acid is used as a pH adjusting agent to maintain the acidity (pH).

In the cosmetic composition containing the triple-coated vitamin AC of the present invention, ethylenediaminetetraacetic aciddisodidecide used for preventing coloration is also called EDTA-2Na, and is widely used as a chelating agent.

Maltodextrin used for stabilization as a triple coating material in the present invention, not only improves collagen synthesis of the cosmetic composition containing vitamin AC, but also facilitates absorption into the skin.

In the present invention, the ultraviolet absorbent contained in the cosmetic composition containing the vitamin AC stabilized by the triple coating is 0.01 to 1.0% by weight, preferably 0.2 to 0.5% by weight. And ethylenediamine tetraacetic acid disodicone is 0.005 to 0.05 weight%, Preferably it is 0.01 to 0.03 weight%.

The cosmetic composition containing vitamin AC stable in the present invention can be produced by containing antioxidants such as dibutyl hydroxytoluene, stearyl trimethylammonium, ricotinic acid, natural vitamin E, and the like, and further excellent antioxidant effect can be obtained.

Hereinafter, specific examples of the present invention will be described in detail through three examples and experimental examples. The embodiments of the present invention described below are merely intended to illustrate the technical idea of the present invention by way of example, and should not be construed as being limited thereto. Various modifications, changes and variations are possible in the art to those skilled in the art which are obvious from the following examples.

Example 1 Preparation of Stabilized Vitamin AC with Triple Coating Structure First, pure Ascorbic Acid and Retinyl palmitate were mixed with Stirrer 30 rpm for 3 minutes at room temperature of 30 ° C. Subsequently, the primary coating (inclusion) is performed by mixing mixed Ascorbic Acid and Retinyl palmitate of liquid crystal type with Phyto collagen at 50 ° C for 5 minutes at room temperature of 30 ° C. The secondary coating (inclusion) was obtained by dissolving and dissolving ascorbic acid + retinyl palmitate + phyto collagen primary coated with vegetable collagen at 30 ° C. with Na-CM-β-Glucan for 30 minutes at room temperature. Ascorbic Acid + Retinyl palmitate + Phyto collagen + Na-CM-β-Glucan secondary coated by Na-CM-β-Glucan as described above, and finally coated (included) with Malto dextrin As a result, it is possible to obtain the vitamin AC of the stabilized triple coating structure required by the present invention.

Example 2 Preparation of Cream Cosmetic Composition Containing Vitamin AC First, 2.00 g of hydrogenated castor oil, 3.00 g of lipophilic monostearate, 2.00 g of self-emulsifying monostearate 2.00 g, cetanol 2.00 g, stearate 3.00 g of lick acid, 8.00 g of caprylic capric triglyceride, 3.00 g of jojoba, 5.00 g of squalane, 0.50 g of natural vitamin E acetate, 0.10 g of propyl paraoxybenzoate, 0.50 g of 2-hydroxy-4-methoxybenzophenone The mixed mixture (A) is prepared.

Then, purified water was added to 5.00 g of glycerin, 2,2-dihydroxy-4,4-dimethoxy-5,5-disulfobenzophenone, 0.50 g, allantoin 0.10 g, and 0.10 g of methyl paraoxybenzoate. The mixture (B) is prepared by heating and dissolving to 100 g.

The mixture (B) is then added to the mixture (A), followed by stirring, emulsification and cooling. 0.02 g of ethylenediaminetetraacetic acid disodium, 2.00 g of retinol palmitate and pure vitamin C, 5.00 g of collagen, 8.00 g of sodium carboxymethyl beta glucan, 8.00 g of malto, to a sample mixed with the mixture (A) and mixture (B) After adding 10.00 g of dextrin and fragrance, the mixture is stirred and mixed to prepare a cream cosmetic composition containing vitamin AC (retinyl palmitate and pure vitamin C). PH of the cream cosmetic composition prepared at this time is 4.0.

Example 3 Preparation of Lotion Cosmetic Composition Containing Vitamin AC

First, 0.50 g of hydrogenated castor oil, 1.00 g of lipophilic monostearic acid, 2.00 g of self-emulsifying monostearate, 2.0 g of cetanol, 0.50 g of jojoba, 3.00 g of squalane, 3.00 g of vitamin E acetate, 0.50 g of paraoxybenzoic acid A mixture (A ') containing 0.10 g of a fill and 0.30 g of 2-hydroxy-4-methoxy benzophenone was prepared.

Then, 5.00 g of glycerin, 0.10 g of carboxyvinyl polymo, disodicul 2,2-dihydroxy-4,4-dimethoxy-5,5-disulfobenzophenone 0.20 g, and 0.10 g of methyl paraoxybenzoate 50 g of purified water Then, the mixture is heated and dissolved to prepare a mixture (B '). Thereafter, the mixture (B ') is added to the mixture (A'), followed by stirring, emulsification and cooling. 0.02 g of ethylenediaminetetraacetic acetate disodium, 0.50 g of retinol palmitate and pure vitamin C, 1.25 g of collagen, and 2.00 g of sodium carboxymethyl betaglucan, respectively, in the sample mixed with the mixture (A ') and the mixture (B'). After adding 2.50 g of maltodextrin, fragrance, and purified water to 100 g of the whole, stirring and mixing, a lotion cosmetic composition containing vitamin AC (retinyl palmitate and pure vitamin C) is finally produced. At this time, the pH of the manufactured lotion cosmetic composition is 4.0.

Experimental Example 1 Antioxidant Effect and Content Change of Cosmetic Composition Containing Vitamin AC>

In order to verify the antioxidant and content change of the composition prepared by the embodiment of the present invention was compared with a number of compositions as follows.

First, 1.00% by weight of hydrogenated castor oil, fragrance, 15.00% by weight of ethanol, 0.1% by weight of paraoxybenzoate, 0.1% by weight of lactic acid, 0.3% by weight of sodium lactate, 1.0% by weight of 1,3-butylene glycol, reti A standard lotion cosmetic composition (a) was prepared, containing 2.0% by weight of neal palmitate, 2.0% by weight of pure vitamin C, and 78.5% by weight of purified water.

A control lotion cosmetic composition (b) to which 0.01 wt% of 2-hydroxyethylenediaminetetraacetic acid was added to the standard lotion cosmetic composition (a), and 2-hydroxy-1-methion to the standard lotion cosmetic composition (a). A control lotion cosmetic composition (c) to which 0.50% by weight of oxybenzophenonesulfonic acid was added, a control lotion cosmetic composition (d) to which 1.25% by weight of collagen was added to the standard lotion cosmetic composition (a), and the standard lotion cosmetic composition (a) A control lotion cosmetic composition (e) to which 2.00% by weight of sodium carboxymethyl betaglucan was added, and a control lotion cosmetic composition (f) to which 2.50% by weight of maltodextrin was added to the standard lotion cosmetic composition (a) were prepared.

The lotion cosmetic composition (g) prepared in Example 3 was placed in a 100 ml beaker, and irradiated with ultraviolet rays (UV A and UV B) at 25 J / cd, and the degree of coloring after 10 days was measured by a colorimeter (Z- 100). In addition, the pure vitamin C content was applied to 50 ml of methanol after sonication for 3 minutes by taking 1-2 g of the sample in 5 ml of isopropyl alcohol.

After sonication for 30 minutes as described above, the sample was treated with a 0.45 μm filter, and each cream was quantitatively analyzed by HPLC (C18, UV325 nm, 30 ° C.) to see how the contents of retinyl palmitate and pure vitamin C were changed. . At this time, the pH of the cosmetic compositions was 4.0.

Table 1 shows the results of quantitative analysis of retinyl palmitate and pure vitamin C content by HPLC after sonicating the cream cosmetic composition containing the triple-coated vitamin AC of the present invention. As a result, as shown in Table 1, it was found that the lotion cosmetic composition containing the triple-coated vitamin AC of the present invention was significantly prevented in coloration compared to other controls and standard products.

Antioxidant Effect of Cosmetic Composition Containing Retinyl Palmitate and Pure Vitamin C Test Material △ E Retinyl palmitate Vitamin-c Standard Cosmetic Composition (a) 9.67 9.48 Control cosmetic composition (b) 7.31 7.12 Control cosmetic composition (c) 6.24 6.09 Control cosmetic composition (d) 3.38 3.21 Control Cosmetic Composition (e) 2.67 2.54 Control Cosmetic Composition (f) 2.36 2.18 Cosmetic composition of the present invention (g) 1.89 1.88

Table 2 shows the changes in the content of retinyl palmitate and vitamin C contained in the standard lotion cosmetic composition (a) and the control compositions (b to f) and the lotion cosmetic composition (g) of the present embodiment. In this embodiment, when the content of retinyl palmitate and vitamin C included in the cosmetic composition prepared initially is 100, respectively, the retinyl palmitate and vitamin C contained in the standard and control lotion cosmetic composition are At the same time, a certain amount of instantaneous deterioration occurred, and the triple-coated vitamin AC (retinyl palmitate and pure vitamin C), as shown in the embodiment of the present invention, was hardly deteriorated and destroyed after its composition. It can be seen that no change occurs in the.

Changes of Retinyl Palmitate and Vitamin C Content in Lotion Cosmetic Composition (residual content;%)  division 1 week 2 weeks 3 weeks 4 Weeks 5 Weeks 6 Weeks Week 7 8 Weeks 9 Weeks 10 Weeks a V.C 27.24 21.45 18.03 15.62 11.74 8.91 7.25 6.44 5.96 5.21 R.P 24.87 20.94 19.36 16.40 12.20 8.67 6.65 5.08 4.19 3.29 b V.C 56.88 55.62 51.07 48.75 44.63 39.39 35.77 32.28 30.50 28.80 R.P 56.73 54.79 52.72 47.54 42.06 38.09 34.72 28.05 27.41 26.93 c V.C 61.22 59.53 56.15 52.70 49.82 46.34 44.45 43.21 41.26 39.15 R.P 61.43 59.03 55.11 51.75 48.66 46.29 44.33 41.73 39.28 37.95 d V.C 78.27 77.61 75.81 73.36 72.29 70.90 69.45 68.78 68.05 67.87 R.P 77.75 76.54 75.62 73.26 72.44 71.65 70.31 69.05 67.46 66.24 e V.C 89.93 87.68 86.85 84.74 83.07 81.31 79.10 77.22 75.46 74.08 R.P 90.05 87.82 85.94 83.37 82.80 79.86 77.66 75.77 74.28 73.30 f V.C 91.84 90.81 88.89 87.65 86.67 84.53 82.81 80.37 79.09 78.22 R.P 92.26 91.05 89.49 86.97 85.96 84.61 81.85 79.72 77.19 76.44  g V.C 98.73 98.34 96.09 92.09 88.64 86.71 84.10 82.55 81.91 81.15 R.P 99.67 96.74 92.91 91.83 86.15 84.27 82.89 82.39 81.71 81.02

(V.C: pure vitamin C, R.P: retinyl palmitate)

The trend for this can be easily confirmed in a graph as shown in Figure 1, it can be seen that the antioxidant effect is excellent compared to other control cosmetic composition.

And, the results of observing the changes in the content of retinyl palmitate and vitamin C contained in the cream cosmetic composition, as shown in Table 3 and Table 4 below, the retinyl palmitate and 12 weeks of the cosmetic composition of the present invention It was found that the change in the content of vitamin C was stabilized.

Change in vitamin C content over time and decrease in initial value (%) division content Reduction rate Sample Treatment District Room temperature storage Early 2.03 0 1 week later 2.02 1.27 after 2 weeks 2.00 1.66 3 weeks later 1.95 3.91 4 weeks later 1.87 7.91 5 weeks later 1.80 11.36 6 weeks later 1.76 13.29 7 weeks later 1.71 15.90 8 weeks later 1.68 17.45 9 weeks later 1.66 18.09 10 weeks later 1.65 18.85 11 weeks later 1.64 19.11 12 weeks later 1.63 19.36

Change in Retinyl Palmitate Content over Time and Reduction in Initial Value (%) division content Reduction rate Sample Treatment District Room temperature storage Early 2.01 0 1 week later 2.00 0.33 after 2 weeks 1.94 3.26 3 weeks later 1.88 7.09 4 weeks later 1.80 8.17 5 weeks later 1.73 13.85 6 weeks later 1.69 15.73 7 weeks later 1.66 17.11 8 weeks later 1.37 17.61 9 weeks later 1.64 18.29 10 weeks later 1.62 18.98 11 weeks later 1.62 19.28 12 weeks later 1.61 19.56

The experimental results were obtained by requesting from the Korea Institute of Chemical Testing, and are obtained through a cream containing triple coated vitamin AC (retinyl palmitate and pure vitamin C). As a specific test method, first, the cream container contained in the BOD glass bottle is opened, the content test is performed according to the retinyl palmitate and vitamin C content test standards, and the results are recorded, and the container is sealed and stored at room temperature. One week after the test date, the container is reopened and retinyl palmitate and pure vitamin C content test is performed in the same manner. As a result, as shown in Tables 3 and 4, stable retinyl palmitate and pure vitamin C content characteristics were decreased after 19 months of retinyl palmitate and 19.36% for pure vitamin C. Could get

As described above, according to the present invention, vitamin AC (retinyl palmitate and pure vitamin C) coated with collagen, sodium carboxymethyl beta glucan, and maltodextrin did not change in content even after sonication, and thus, an ultraviolet absorber and ethylenediamine were used. When containing tetraacetic acid and included in a conventional cosmetic composition having a pH of 3.5 to 5.0 it was confirmed that there is an excellent effect of wrinkle improvement and skin whitening and antioxidant effect.

Figure 1 is a graph of the quantitative analysis of the retinyl palmitate and pure vitamin C content of the cosmetic composition containing the triple-coated retinyl palmitate and pure vitamin C of the present invention, and after sonicating other compositions.

Claims (5)

Vitamin AC (retinyl palmitate and pure vitamins) having a triple coating structure characterized by coating and stabilizing collagen, sodium carboxymethyl beta glucan and maltodextrin sequentially on the surface of the mixture of retinyl palmitate and pure vitamin C. C). The mixture of retinyl palmitate and pure vitamin C is 5 to 10% by weight, 15 to 20% by weight of collagen, 25 to 35% by weight of sodium carboxymethyl betaglucan and malto Vitamin AC (retinyl palmitate and pure vitamin C) of a triple coating structure, characterized in that 35-40% by weight of dextrin is coated. A cosmetic composition containing 0.01 to 1.0% by weight of a ultraviolet absorber and 0.005 to 0.05% by weight of ethylenediaminetetraacetic acid, each containing 0.1 to 2% by weight of retinyl palmitate and pure vitamin C according to claim 1, respectively. A cosmetic composition containing vitamin AC (retinyl palmitate and pure vitamin C) having a triple coating structure. Hydrogenated castor oil 2.00g, lipophilic monostearic acid glycerin 3.00g, self-emulsifying monostearic acid glycerin 2.00g, stearic acid 3.00g, cetanol 2.00g, jojoba oil 3.00g, squalane 5.00g, caprylic capric A first mixture of 8.00 g of triglycerides, 0.50 g of natural vitamin E acetate, 0.10 g of propyl paraoxybenzoate and 0.50 g of 2-hydroxy-4-methoxybenzophenone; Purified water was added to 5.00 g of glycerin, 0.50 g of disodicone 2,2-dihydroxy-4,4-dimethoxy-5,5-disulfobenzophenone, 0.10 g of allantoin, and 0.10 g of methyl paraoxybenzoate, adding 100 g of all Forming a second melted mixture; After the first mixture and the second mixture were added, stirred, emulsified and cooled, 0.02 g of ethylenediaminetetraacetic acid disodium, retinyl palmitate and pure vitamin were added to the sample mixed with the first mixture and the second mixture. C, 2.00 g each, collagen 5.00 g, sodium carboxymethyl beta glucan, 8.00 g, maltodextrin 10.00 g and flavorings were added to the acidity (pH) 4.0 by stirring and mixing, vitamin AC (retinyl palmi) A cream cosmetic composition containing tate and pure vitamin C). Hydrogenated castor oil 0.50g, lipophilic monostearic acid 1.00g, self-emulsifying monostearic acid glycerin 2.00g, stearic acid 1.00g, cetanol 0.50g, caprylic capric triglyceride 5.00g, jojoba oil 3.00g A third mixture formed by mixing 3.00 g of squalane, 0.50 g of vitamin E acetate, 0.10 g of paraoxybenzoic acid pyrophyll, and 0.30 g of 2-hydroxy-4-methoxy benzophenone; 50 g of purified water was added to 5.00 g of glycerin, 0.10 g of carboxyvinyl polymo, 0.20 g of disodicone 2,2-dihydroxy-4,4-dimethoxy-5,5-disulfobenzophenone, and 0.10 g of methyl paraoxybenzoate. Forming a fourth melted mixture; The fourth mixture was added to the third mixture, stirred, emulsified and cooled, and then 0.02 g of ethylenediaminetetraacetic acid disodium, retinyl palmitate, and the like were mixed with the third mixture and the fourth mixture. 0.50 g of pure vitamin C, 1.25 g of collagen, 2.00 g of sodium carboxymethyl beta glucan, 2.50 g of maltodextrin, aroma and purified water were added and stirred and mixed so that the total weight was 100 g. A lotion cosmetic composition containing vitamin AC (retinyl palmitate and pure vitamin C) having a triple coating structure.