KR100468978B1 - 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산 - Google Patents

분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산 Download PDF

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Publication number
KR100468978B1
KR100468978B1 KR10-2001-7007461A KR20017007461A KR100468978B1 KR 100468978 B1 KR100468978 B1 KR 100468978B1 KR 20017007461 A KR20017007461 A KR 20017007461A KR 100468978 B1 KR100468978 B1 KR 100468978B1
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KR
South Korea
Prior art keywords
polypeptide
sequence
amino acid
pro
nucleic acid
Prior art date
Application number
KR10-2001-7007461A
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English (en)
Korean (ko)
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KR20010101224A (ko
Inventor
데이비드 보츠타인
루크 데스노이어스
나폴레옹 페라라
셔만 퐁
웨이-퀴앙 가오
오드리 고다드
오스틴 엘. 거니
제임스 판
마가렛 안 로이
티모시 에이. 스튜워트
다니엘 투마스
콜린 케이. 와따나베
윌리엄 아이. 우드
Original Assignee
제넨테크, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1999/012252 external-priority patent/WO1999063088A2/en
Application filed by 제넨테크, 인크. filed Critical 제넨테크, 인크.
Publication of KR20010101224A publication Critical patent/KR20010101224A/ko
Application granted granted Critical
Publication of KR100468978B1 publication Critical patent/KR100468978B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR10-2001-7007461A 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산 KR100468978B1 (ko)

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US11285198P 1998-12-16 1998-12-16
US11314598P 1998-12-16 1998-12-16
US60/112,851 1998-12-16
US60/113,145 1998-12-16
US11351198P 1998-12-22 1998-12-22
US60/113,511 1998-12-22
US11555899P 1999-01-12 1999-01-12
US11573399P 1999-01-12 1999-01-12
US11556599P 1999-01-12 1999-01-12
US60/115,558 1999-01-12
US60/115,733 1999-01-12
US60/115,565 1999-01-12
US11934199P 1999-02-09 1999-02-09
US60/119,341 1999-02-09
US11953799P 1999-02-10 1999-02-10
US60/119,537 1999-02-10
US11996599P 1999-02-12 1999-02-12
US60/119,965 1999-02-12
PCT/US1999/012252 WO1999063088A2 (en) 1998-06-02 1999-06-02 Membrane-bound proteins and nucleic acids encoding the same
USPCT/US99/12252 1999-06-02
PCT/US1999/028634 WO2000036102A2 (en) 1998-12-16 1999-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same

Related Child Applications (4)

Application Number Title Priority Date Filing Date
KR10-2004-7006173A Division KR100459831B1 (ko) 1999-01-12 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산
KR10-2004-7006172A Division KR100468975B1 (ko) 1999-02-12 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산
KR10-2004-7013508A Division KR100468977B1 (ko) 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산
KR10-2004-7006174A Division KR100468976B1 (ko) 1999-02-10 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산

Publications (2)

Publication Number Publication Date
KR20010101224A KR20010101224A (ko) 2001-11-14
KR100468978B1 true KR100468978B1 (ko) 2005-02-02

Family

ID=27578476

Family Applications (2)

Application Number Title Priority Date Filing Date
KR10-2004-7013508A KR100468977B1 (ko) 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산
KR10-2001-7007461A KR100468978B1 (ko) 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR10-2004-7013508A KR100468977B1 (ko) 1998-12-16 1999-12-01 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산

Country Status (8)

Country Link
EP (1) EP1141285A2 (es)
JP (5) JP2003521229A (es)
KR (2) KR100468977B1 (es)
AU (7) AU777006B2 (es)
CA (1) CA2348757A1 (es)
IL (11) IL142794A0 (es)
MX (1) MXPA01006057A (es)
WO (1) WO2000036102A2 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
US7419663B2 (en) 1998-03-20 2008-09-02 Genentech, Inc. Treatment of complement-associated disorders
US6914130B2 (en) * 1998-06-17 2005-07-05 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
CN1637019A (zh) * 1999-03-11 2005-07-13 Rmf迪克塔吉恩有限公司 血管粘着分子及其功能的调节
AU2008201101B2 (en) * 1999-03-11 2011-01-20 Merck Serono Sa Vascular adhesion molecules and modulation of their function
KR100543857B1 (ko) * 1999-09-01 2006-01-23 제넨테크, 인크. 혈관신생 및 심혈관형성의 촉진 또는 억제
DE19947010A1 (de) * 1999-09-30 2001-04-05 Universitaetsklinikum Freiburg Das Gen PRV-1 und dessen Verwendung
US20020006653A1 (en) * 2000-04-28 2002-01-17 Meyers Rachel A. 25692, a novel human O-Methyltransferase family member and uses thereof
GB0110273D0 (en) * 2001-04-26 2001-06-20 Inpharmatica Ltd Novel proteins
MXPA04005945A (es) * 2001-12-19 2004-11-01 Genentech Inc Composiciones y metodos para el diagnostico y tratamiento de tumores.
WO2003097862A1 (fr) * 2002-05-17 2003-11-27 Kyowa Hakko Kogyo Co., Ltd. Procede de recherche de matiere possedant une activite antidiabetique
EP1546341A1 (en) * 2002-10-02 2005-06-29 DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung Mipp1 homologous nucleic acids and proteins involved in the regulation of energy homeostatis
NZ594285A (en) 2005-11-04 2013-02-22 Genentech Inc USE OF COMPLEMENT PATHWAY INHIBITOR ANTIBODY AGAINST C5a TO TREAT OCULAR DISEASES
CA2663243A1 (en) 2006-09-28 2008-04-03 Merck Serono S.A. Junctional adhesion molecule-c (jam-c) binding compounds and methods of their use
KR20160092061A (ko) 2006-11-02 2016-08-03 제넨테크, 인크. 인간화 항-ｄ 인자 항체
AR066660A1 (es) 2007-05-23 2009-09-02 Genentech Inc Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
EP3141560A3 (en) 2008-05-06 2017-05-24 Genentech, Inc. Affinity matured crig variants
CR20160132A (es) 2013-08-12 2016-08-25 Genentech Inc Composiciones y método para tratar condiciones asociadas con el complemento
MX2016014160A (es) 2014-05-01 2017-02-16 Genentech Inc Variantes del anticuerpo anti-factor d y sus usos.
WO2017075252A1 (en) 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibody variant conjugates and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0791009A4 (en) * 1994-11-07 2003-03-05 Merck & Co Inc MODIFIED NEUROPEPTIDE Y RECEPTOR
AU1532697A (en) * 1996-01-12 1997-08-01 Genetics Institute Inc. Beta-chemokine, h1305 (mcp-2)
JP3646191B2 (ja) * 1996-03-19 2005-05-11 大塚製薬株式会社 ヒト遺伝子
CA2289118A1 (en) * 1997-05-06 1998-11-12 Zymogenetics, Inc. Novel tumor antigens
DE19818620A1 (de) * 1998-04-21 1999-10-28 Metagen Gesellschaft Fuer Genomforschung Mbh Menschliche Nukleinsäuresequenzen aus Blase-Normal
WO2000000610A2 (en) * 1998-06-26 2000-01-06 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
WO2000004135A2 (en) * 1998-07-16 2000-01-27 Incyte Pharmaceuticals, Inc. Human scad-related molecules, scrm-1 and scrm-2
DE19849044A1 (de) * 1998-10-23 2000-04-27 Univ Ludwigs Albert Das Gen PRV-1 und dessen Verwendung
EP1131428A2 (en) * 1998-11-19 2001-09-12 Incyte Pharmaceuticals, Inc. Immunoglobulin superfamily proteins
DK1632499T3 (da) * 1999-03-08 2007-10-01 Genentech Inc Gensekvenser amplificeret i tumorer og diagnistiske anvendelser deraf

Also Published As

Publication number Publication date
JP2003521229A (ja) 2003-07-15
JP2007312779A (ja) 2007-12-06
AU2004237921A1 (en) 2005-01-13
IL200883A0 (en) 2010-05-17
AU2004237923B2 (en) 2007-09-06
JP2004041217A (ja) 2004-02-12
IL188577A0 (en) 2008-04-13
AU2004237919B2 (en) 2007-09-06
AU2004237920A1 (en) 2005-01-13
KR100468977B1 (ko) 2005-02-02
JP2007075118A (ja) 2007-03-29
IL188576A0 (en) 2008-04-13
JP2004041218A (ja) 2004-02-12
AU2004237922A1 (en) 2005-01-13
AU2004237919A1 (en) 2005-01-13
WO2000036102A3 (en) 2000-11-09
MXPA01006057A (es) 2003-09-10
IL142794A (en) 2008-03-20
AU2004237922B2 (en) 2007-09-06
IL142794A0 (en) 2002-03-10
AU2004237842A1 (en) 2005-01-13
AU2004237842B2 (en) 2007-09-20
IL188580A0 (en) 2008-04-13
AU1932000A (en) 2000-07-03
AU777006B2 (en) 2004-09-30
KR20010101224A (ko) 2001-11-14
CA2348757A1 (en) 2000-06-22
IL188581A0 (en) 2008-04-13
WO2000036102A2 (en) 2000-06-22
AU2004237920B2 (en) 2007-08-23
IL201030A0 (en) 2010-05-17
IL188579A0 (en) 2008-04-13
IL188578A0 (en) 2008-04-13
AU2004237921B2 (en) 2007-08-23
IL201001A0 (en) 2010-05-17
AU2004237923A1 (en) 2005-01-13
EP1141285A2 (en) 2001-10-10
KR20040096629A (ko) 2004-11-16

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