KR100449464B1 - Prochloraz Mixtures - Google Patents

Abstract

(2-ethylhexyl) ethyl] -1,2,3,4-tetrachlorophthalide (generic name: phthalide) and 1- { Carbamoyl} imidazole (proclorase) is mixed to provide a novel fungicidal composition for agricultural use.

Description

Prochloraz Mixtures {Prochloraz Mixtures}

The present invention relates to an agricultural fungicidal composition.

(I) wherein the general name is prochloraz, such as 1- {N-propyl-N- [2- (2,4,6-trichlorophenoxy) ethyl] carbamoyl} imidazole, 7-Tetrachlorophthalide has already been used individually as an agricultural fungicide.

Phthalide has been used to control rice blast fungus and has a very safe and excellent preventive effect on mammals as well as on fish and shellfish. However, its use is limited to fungicides for prophylaxis. For example, once infected by Pyricularia oryzae, it is ineffective in controlling paddy plants.

On the other hand, Proclaz has been used as a disinfectant for rice seed, but it has not been directly applied to paddy plants.

Accordingly, it is an object of the present invention to provide a compound effective for controlling blast fungus which can be directly applied to a plant of a paddy field.

Surprisingly, the present inventors have found that this compound has an excellent preventive and control effect on rice blast fungus by directly spraying the compound on a greenhouse in both greenhouse and field.

The present inventors have surprisingly found that phthalide exhibits remarkable synergism by using phthalide in combination with prochloraz.

The fungicidal compositions of the present invention exhibit an unpreferable synergistic effect from the properties of the individual components, in particular the extremely good control of the pyricularia. The composition exhibits not only a preventive effect but also an excellent controlling effect, resulting in a reduction in the amount of the two compounds required compared with the use of one component alone. The fungicidal compositions for agriculture according to the present invention are also particularly effective for the control of spot diseases (e.g., infestation) and fusarium of rice.

The ratio of prochloraz to phthalide varies considerably, but is generally from 4: 1 to 1: 4 by weight, preferably from 2: 1 to 1: 2, and particularly preferably from 1: 1.3 to 1: 1.6.

The agricultural fungicide according to the present invention is provided according to a known method for producing such a preparation in various preparation forms such as dust, granule, dust granule mixture, wet powder, suspension concentrate, emulsion concentrate (EC) can do. As auxiliary substances for preparing these formulations, for example, solid carriers such as diatomaceous earth, calcined lime, calcium carbonate, talc, white carabons, talc, bentonite and zeolite; A solvent such as toluene, xylene, naphtha, ethanol, dioxane, acetone, isophorone, methyl isobutyl ketone, dimethyl formamide, dimethyl sulfoxide and N-methyl-2-pyrrolidone; Wetting agents such as sodium alkylsulfonate, sodium alkylbenzenesulfonate, sodium ligninsulfonate, polyoxyethylene glycol alkyl ether, polyoxyethylene lauryl ether, polyoxyethylene alkylauryl ether, polyoxyethylene sorbitan fatty acid esters, Examples of other various surfactants to be used include surfactants.

The fungicide composition for agricultural use according to the present invention shows high stability against mammals and fishes and shows little or no phytotoxicity to crops, especially rice.

The fungicide composition for agricultural use can be used in combination with insecticides, herbicides and plant growth regulators as well as other fungicides.

The agricultural fungicide formulations according to the invention generally comprise from 1.0 to 95.0%, preferably from 3.0 to 70% of the active compound, of the total amount of the two active compounds. The dosage of the formulation is generally from 150 to 600 g, preferably from 250 to 400 g, of the active compound combined per hectare.

The following examples are presented to illustrate the preparation of fungicide compositions for agriculture according to the present invention.

Formulation 1 (non-flux dust)

The dust was obtained by uniformly mixing 1.5 parts by weight of prochloraz, 1.5 parts by weight phthalide, 1.0 part by weight of white carabons, 0.5 part by weight of flocculant and 95.5 parts by weight of clay.

Formulation 2 (wet powder)

The wet powder was obtained by homogeneously mixing 15.0 parts by weight of prochloraz, 15.0 parts by weight of phthalide, 5.0 parts by weight of sodium lignin sulfate, 15.0 parts by weight of white carabine and 50.0 parts by weight of kaolin.

Formulation 3 (granule)

The granules were obtained by uniformly mixing 1.5 parts by weight of prochloraz, 1.5 parts by weight of phthalide, 30.0 parts by weight of bentonite and 67.0 parts by weight of clay according to a conventional method.

The fungicidal action of the composition according to the present invention on the Pyricularia oryzae is illustrated in the following examples.

≪ Example 1 >

Control of Pyricularia oryzae

3-4 leaf stage rice (variety: Nihonbare) cultivated in solid pots in a plastic pot with a diameter of 9 ㎝ was used for the test, and both prevention and control effects were examined.

The active ingredients may be in the form of their commercially available formulations; Phthalide was used as the 20% suspension concentrate and procollase as 25% EC and diluted to the predetermined concentration. The diluted formulations were sprayed to the plants in an amount of 30 ml per 3 pots.

Plants were sprayed with spore suspension (5-6 x 10 ⁶ / ml) of Pyricularia oryzae obtained from rice infected with blast flame in advance.

In the preliminary test, plants were inoculated one day after the test compound was added, then placed in a wet room at 25 ± 2 ° C for 24 hours, then left in the greenhouse to await the effect of the disease.

In the control test, 24 hours after the test substance was inoculated with the fungi, the test substance was added. The plants were then placed in the greenhouse to await the effects of the disease.

The degree of infection can be calculated according to the following equation by measuring the loss up to 7 days after inoculation.

Degree of damage in untreated pot - Degree of damage of treated pot

Defensive value = ━━━━━━━━━━━━━━━━━━━━━━━━ x 100

Degree of damage in untreated pot

Results of the test

1. Prevention effect

Test plot compound Concentration (ppm a.i.) Defensive value Plots treated with a single compound Phthalide 2550100200 677598100 Prochloraz 2550100 254267 Plots treated with a mixture of compounds Prochloraz + phthalide (ratio) 25 + 25 (1: 1) 50 + 50 (1: 1) 100 + 100 (3: 3) 9494100 25 + 50 (1: 2) 50 + 100 (1: 2) 100 + 200 (1: 2) 8810098 25 + 38 (2: 3) 50 + 75 (2: 3) 100 + 150 (2: 3) 9810099 38 + 25 (3: 2) 75 + 50 (3: 2) 9599 Raw plot 80% damage

2. Control effect

Test plot compound Concentration (ppm a.i.) Defensive value Plots treated with a single compound Phthalide 163264125 0000 Prochloraz 3264125 100100100 Plots treated with a mixture of compounds Prochloraz + Phthalide 16 + 3232 + 3264 + 32125 +3216 + 6432 + 6464 + 6416 + 12532 + 12564 + 125 100100100100100100100100100100100 Raw plot 80% damage

≪ Example 2 >

Control of Pyricularia oryzae in highland rice seedlings

Rice seeds (cultivar: Nihonbare) were sown on rice seedlings that had not been irrigated. To promote disease development, uniform leaves were attacked with Pyricularia oryzae, cut to a length of about 1 cm, and spread evenly on the packaging as an inoculum. As a result, the paddy rice was infected with blast.

The formulation to be tested was prepared according to Example 1 and applied at the predetermined concentration by spraying twice with a small atomizer at a rate of 100 ml per plot.

The first spray was performed at the 3-4 leaf stage and the scars appeared at the 2 leaf, 3 leaf stage and the second spray appeared after 7 days.

Examination of the outbreak of the disease was carried out three times. That is, the effect of controlling the formulation was evaluated by performing 7 days after the first spraying, immediately before (first), 2 days after the second spray (second), and 8 days (third) after the second spray.

The degree of damage due to blast damage in% was evaluated on each treated plot, and the defensive value of each formulation was calculated according to the formula of Example 1. [ The test result is as follows.

Test plot compound Concentration (ppm a.i.) Defense value after inspection One 2 3 Plots treated with a single compound Phthalide 100150200 225039 01726 71126 Prochloraz 150200250 224444 264339 305248 Plots treated with a mixture of compounds Prochloraz + phthalide (ratio) 100 + 100150 + 150100 + 200100 + 250150 + 100150 + 150150 + 200150 + 250 5672728378787861 4865707465787078 6767858974859191 Kasu-Rab wet powder (1.2% of casimizin + 15% of phthalide combination formulation) 12 + 150 67 65 67 Raw plot damaged% - 60% 77% 90%

The fungicidal compositions of the present invention exhibit an unpreferable synergistic effect from the properties of the individual components, in particular the extremely good control of the pyricularia. The composition exhibits not only a preventive effect but also an excellent controlling effect, resulting in a reduction in the amount of the two compounds required compared with the use of one component alone. The fungicidal compositions for agriculture according to the present invention are also particularly effective for the control of spot diseases (e.g., infestation) and fusarium of rice.

Claims (1)

(4,5,6,7-tetrachlorophthalide (phthalide) and 1- {N-propyl-N- [2- (2,4,6-trichlorophenoxy) ethyl] carbamoyl} imidazole (Prochloraz) in a weight ratio of 4: 1 to 1: 4.