KR100388786B1 - Composition for prevention and treatment of liver cirrhosis, containing phenolic compound - Google Patents

Composition for prevention and treatment of liver cirrhosis, containing phenolic compound Download PDF

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Publication number
KR100388786B1
KR100388786B1 KR1020020036746A KR20020036746A KR100388786B1 KR 100388786 B1 KR100388786 B1 KR 100388786B1 KR 1020020036746 A KR1020020036746 A KR 1020020036746A KR 20020036746 A KR20020036746 A KR 20020036746A KR 100388786 B1 KR100388786 B1 KR 100388786B1
Authority
KR
South Korea
Prior art keywords
composition
prevention
treatment
liver cirrhosis
phenolic compound
Prior art date
Application number
KR1020020036746A
Other languages
Korean (ko)
Inventor
Mi Sook Dong
Nam Chul Jung
Chun Soo Na
Original Assignee
Lifetree Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifetree Biotech Co Ltd filed Critical Lifetree Biotech Co Ltd
Priority to KR1020020036746A priority Critical patent/KR100388786B1/en
Application granted granted Critical
Publication of KR100388786B1 publication Critical patent/KR100388786B1/en
Priority to PCT/KR2003/001269 priority patent/WO2004002471A1/en
Priority to AU2003244260A priority patent/AU2003244260A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L11/00—Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
    • A23L11/05—Mashed or comminuted pulses or legumes; Products made therefrom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10—Cereal-derived products
    • A23L7/198—Dry unshaped finely divided cereal products, not provided for in groups A23L7/117 - A23L7/196 and A23L29/00, e.g. meal, flour, powder, dried cereal creams or extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Agronomy & Crop Science (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: A composition for prevention and treatment of liver cirrhosis, containing phenolic compound is provided, which can be used as medicines or healthy foods for prevention and treatment of liver cirrhosis. CONSTITUTION: The composition for prevention and treatment of liver cirrhosis contains one or more phenolic compounds selected from protocatechuic acid, butein, fustin, sulfuretin and fisetin, wherein the composition is administered orally or nonorally in the amount of 10 to 200 mg/kg per a day, preferably 25 to 100 mg/kg per a day; the composition is added into foods in the amount of 0.1 to 15 wt.%, preferably 1 to 10 wt.%; and the composition is added into drinks in the amount of 1 to 30g, preferably 3 to 10g per 100 ml of drinks.
KR1020020036746A 2002-06-28 2002-06-28 Composition for prevention and treatment of liver cirrhosis, containing phenolic compound KR100388786B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1020020036746A KR100388786B1 (en) 2002-06-28 2002-06-28 Composition for prevention and treatment of liver cirrhosis, containing phenolic compound
PCT/KR2003/001269 WO2004002471A1 (en) 2002-06-28 2003-06-27 Composition comprising phenolic compound for preventing and treating liver cirrhosis
AU2003244260A AU2003244260A1 (en) 2002-06-28 2003-06-27 Composition comprising phenolic compound for preventing and treating liver cirrhosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020020036746A KR100388786B1 (en) 2002-06-28 2002-06-28 Composition for prevention and treatment of liver cirrhosis, containing phenolic compound

Publications (1)

Publication Number Publication Date
KR100388786B1 true KR100388786B1 (en) 2003-06-25

Family

ID=29997398

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020020036746A KR100388786B1 (en) 2002-06-28 2002-06-28 Composition for prevention and treatment of liver cirrhosis, containing phenolic compound

Country Status (3)

Country Link
KR (1) KR100388786B1 (en)
AU (1) AU2003244260A1 (en)
WO (1) WO2004002471A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06192201A (en) * 1992-09-10 1994-07-12 Behringwerke Ag Substituted phenoles, their preparation and their use for treatment of disease caused by cell proliferation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54160740A (en) * 1978-06-09 1979-12-19 Takeda Chem Ind Ltd Anti-fibrotic agent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06192201A (en) * 1992-09-10 1994-07-12 Behringwerke Ag Substituted phenoles, their preparation and their use for treatment of disease caused by cell proliferation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
1쪽 요약, Drugs Exp Clin Res., 1999, 25(2-3), 143-145 *
Drugs Exp.Clin.Res., 1999, 25(2/3), pages 143-145 *

Also Published As

Publication number Publication date
WO2004002471A1 (en) 2004-01-08
AU2003244260A1 (en) 2004-01-19

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