KR0169743B1 - Synergistic microbiocidal composition of 2-(decylthio)ethane amine and 1,2-dibromo-2,4-dicyanobutane - Google Patents

Abstract

The present invention relates to a combination of two bactericidal substances that have a synergistic action against microorganisms in aqueous plants to the extent that they kill the microorganisms in excess of the lethality obtained using the sum of the individual components of the composition. More specifically, the present invention relates to a combination of a microbial growth inhibitory effective amount consisting of 2- (decylthio) ethanamine and 1,2-dibromo-2,4-dicyanobutane. This combination has been found to be particularly effective in inhibiting the growth of Enterobacter aerogenes ATCC 13048 in aqueous plants.

Description

[Name of invention]

Synergistic bactericidal composition of 2- (decylthio) ethanamine and 1,2-dibromo-2,4-dicyanobutane

Detailed description of the invention

The present invention relates to the treatment of aqueous plants, more particularly to sterilizing substances having synergism against microorganisms commonly found in aqueous industrial plants such as cooling water plants, air scrubber plants and pulp and paper mill plants.

Slime formation by microorganisms is a problem encountered in many aqueous industrial installations. For example, tap water is usually used in industrial cooling water plants and untreated river water is used for large plants. The water itself is not sterilized, causing bacteria to accumulate in the facility. In addition, as the plant moves below the tower fan, a significant amount of bacteria enter the air. This creates a slime deposit on the surface of the plant in direct contact with the cooling water. Since both the one-time cooling system and the circulation cooling system use a large amount of water as a cooling medium, the formation of mucus by microorganisms has been a problem that has been extensively continued.

The formation of mucus not only deactivates the tower structure in the case of wooden towers, but can also clog the device, which, if left to accumulate, reduces efficiency. Mucus is transported through the cooling plant plugs to contaminate lines, valves, strainers and the like. Bacteria are transferred through the plant to water deposits on the surface, such as heat exchange surfaces, to form lumps of mucus that interfere with heat transfer, significantly reducing the efficiency of the cooling plant. Mucus deposits also provide a favorable environment for the growth of anaerobic bacteria that grow well in low oxygen environments below mucus. These anaerobic microorganisms can puncture the metal surface or cause corrosion.

In pulp and paper mill equipment, mucus formed by microorganisms is often seen, which causes contamination, blockage or corrosion of the equipment. Mucus also enters the paper produced and ruptures the paper on the paper machine, leading to downtime and loss of production time. Mucus also causes unpleasant stains in the final product, resulting in rejects and waste products.

These problems have led to the widespread use of disinfectants in cooling water plants and pulp and paper mill facilities. Various materials have been used for this purpose, including chlorine, chlorinated phenols, organobromine and various organo-sulfur compounds. All of these compounds are usually useful for this purpose, but each of them involves various problems. Chlorination, for example, is limited by the specific toxicity and the tendency of reaction with chlorine at an economic level to the organisms that form mucus, resulting in large consumption of chlorine before sufficient bactericidal action is achieved. Other fungicides carry odor problems that limit their use and risks in terms of storage, use or handling. To date, there have been no clear compounds or compounds that are clearly superior in terms of the use discussed above. The use of fungicides involves adding to facilities that are processed continuously or frequently and may need to be added to multiple points or areas within these facilities.

It is an object of the present invention to provide novel bactericidal compositions for inhibiting the growth of microorganisms in aqueous plants.

Another object of the present invention is to provide a bactericidal composition containing a combination of 2- (decylthio) ethanamine and 1,2-dibromo-2,4-dicyanobutane, which has a synergistic action against microorganisms in aqueous equipment. Exist to provide.

According to the present invention, a bactericidal composition comprising a mixture of 1,2-dibromo-2,4-dicyanobutane and 2- (decylthio) ethanamine and adding the composition to an aqueous plant in an effective amount to inhibit microbial growth Provided are methods of using the composition, including the above.

The present invention relates to a combination of two bactericidal substances that have a synergistic action against microorganisms in aqueous plants to the extent that they kill the microorganisms in excess of the lethality obtained using the sum of the individual components of the composition. More specifically, the present invention relates to a composition for inhibiting microorganism growth effective amount consisting of 2- (decylthio) ethanamine and 1,2-dibromo-2,4-dicyanobutane. This combination is particularly effective in inhibiting the growth of Enterobacter aerogenes ATCC 13048 in aqueous plants.

2- (decylthio) ethanamine is manufactured by Dow Chemical Company under the trade name DTEA or XU40304.01L according to US Pat. No. 4,816,061. 1,2-Dibromo-2,4-dicyanobutane is manufactured by Merck Chemicals subsidiary Calgon Corporation in accordance with US Pat. Nos. 3,833,731, 3,873,597, 3,877,922 and 3,929,858.

The bactericidal composition of the present invention is most effective when added to an aqueous installation of pH 7 or higher, preferably pH 8-9. Each fungicide component of the composition may be added to the facility individually or in advance in an effective amount to inhibit microbial growth. 2- (decylthio) ethanamine is usually added to the plant at a concentration of 0.7 to 1.2 ppm, while 1,2-dibromo-2,4-dicyanobutane is usually added at a concentration range of 4.0 to 12.0 ppm. The concentration of total fungicides in aqueous plants is usually in the range of 5 to 14 ppm, preferably 5.2 to 13.2 ppm.

The following examples are provided to illustrate the invention in accordance with the principles of the invention, but do not limit the invention except as indicated in the appended claims. All parts and percentages are by weight unless otherwise noted.

Example 1

The combination of 2- (decylthio) ethanamine and 1,2-dibromo-2,4-dicyanobutane is evaluated for synergistic action against Enterobacter aerogenes ATCC # 13048. The result is as follows.

Example 2

Example Description

Claims (7)

It consists of a synergistic mixture of 2- (decylthio) ethanamine and 1,2-dibromo-2,4-dicyanobutane in an effective amount of microorganism growth inhibition, and 2- (decylthio) ethanamine and 1,2 A sterilizing composition wherein the weight ratio of dibromo-2,4-dicyanobutane is 0.7 to 1.2: 4 to 12, respectively. Inhibiting microbial growth Inhibiting the growth of microorganisms in an aqueous plant comprising adding to the plant a composition comprising an effective amount of a mixture of 2- (decylthio) ethanamine and 1,2-dibromo-2,4-dicyanobutane How to let. The method of claim 2, wherein the aqueous facility is maintained at pH 7 or above. The method of claim 2, wherein the aqueous facility is maintained at pH 8-9. The method of claim 2, wherein the weight ratio of 2- (decylthio) ethanamine and 1,2-dibromo-2,4-dicyanobutane is 0.7 to 1.2: 4 to 12, respectively. The method of claim 2 wherein the aqueous facility is a cooling water facility. The method of claim 2 wherein the aqueous facility is a pulp and paper making facility.