KR0115807Y1 - Skin treatment device for medication - Google Patents

Abstract

A skin scratch forming device for administering a medicine for forming a skin scratch is disclosed, which is laminated on the outer circumferential surface of the skin needle formed with the skin needles at equal intervals at a predetermined interval in the direction of the central axis of the skin needle disc, and then ends The outer surface of the skin needle disc is provided with a reinforcing plate to make the depth of the scratches constant, the treatment depth by both ends of the skin needle plate is uniform, there is no pain and no redness occurs. In addition, by roughening the tip of the skin needle to increase the contact area with the skin to make it easy to scratch the skin.

Description

Skin Scratches for Drug Administration

1 is a side cross-sectional view of an insulin transdermal administration device according to the prior art.

Figure 2 is an assembled front view showing the skin scratch formation sphere for drug administration according to the first embodiment of the present invention.

3 is an exploded perspective view of the main part of FIG. 2;

4 is an enlarged perspective view of the main part of FIG. 2;

5 is an enlarged view illustrating main parts of FIG. 2.

Figure 6 is an assembled front view showing the skin scratch formation sphere for drug administration according to the second embodiment of the present invention.

7 is an enlarged view of the main part of FIG.

* Explanation of symbols for main parts of the drawings

10: skin needle disc 12: skin needle

14 shaft hole 16 fixing hole

20: spacer member 30: central axis

34: reinforcing member

The present invention relates to a skin flaw forming device for forming thousands of skin flaws on the skin for administering a liquid or gel medicament to a human body, and more particularly to maintain a gap at both ends of the skin needle assembly. The present invention relates to a skin scratch forming device for drug administration to maximize the skin treatment effect by placing an intermediate material so that the pretreatment depth is uniform over the entire width of the skin needle.

In general, medicines such as insulin are particularly useful for diabetics. Since insulin is composed of macromolecules of 6,000 or more molecular weight, it is impossible to penetrate the epidermal layer even if chemical properties are used to change skin properties. As a peptide conjugate of amino acids, it has a strong hydrophilic drug, and thus does not have good affinity with a hydrophobic epidermal layer. Therefore, insulin itself is well known as it cannot penetrate the epidermal layer and cannot be delivered into the skin. The human skin is composed of epidermal, transdermal and dermal layers, of which the most difficult drug delivery is composed of 20% lipid and 40% protein, the thickness of which is at least 0.1 mm. In addition, the epidermal layer has a structure in which lipids surround each segment of the protein, so that the epidermal properties are hydrophobic. In the dermal and transdermal layers, the moisture content of the epidermal layer is 70% or more, whereas the epidermal layer has only about 40% moisture content. It is large in resistance and acts to protect the dermal layer from thermal and other external stimuli.

In general, ointment, patch type, and spray type are commonly used as a transdermal administration method for administering insulin through the human skin. Among these, a transdermal administration method using a patch type has been actively researched and developed. Conventional transdermal administration device for insulin patch by transdermal administration method is disclosed in Korean Patent Publication No. 92-2264. As shown in FIG. 1, the apparatus comprises an insulin solvent reservoir 1 which forms the main part of the patch body, a polymer support 2 having water swellability while insulin is dispersed in powder form, and adhesion to skin. After the release of the solvent, a dermal needle support 3 exhibiting swelling, a plurality of dermal needles 4 and an insulin solvent reservoir 1 fixedly distributed perpendicularly to the dermal needle support 3 to come into contact with the skin; It consists of an electrode (5) installed inside the upper end of the insulin solvent reservoir (1) so that electricity can be supplied to the skin.

In the conventional insulin patch transdermal administration device as described above, when the dermal needle 4 of the dermal needle support 3 is attached to the skin, the passage formed by the dermal needle 4 is temporarily closed by swelling of the skin. When a direct current or a pulse is applied to the electrode 5 inside the upper portion of the insulin solvent reservoir 1, the ionized insulin and the solvent move toward the opposite electrode. At this time, the hydrophilic protein and the polypeptide of the skin are arranged in parallel toward the anode so that the contraction occurs, the passage of the epidermal layer is opened, and the insulin in the passage passes through the dermal layer.

The reason for using multiple skin needles 4 is to penetrate only the epidermal layer of the skin having a thickness of 0.1 mm or more so that insulin can be easily moved from the epidermal layer through the transdermal layer and the dermis into the capillaries to increase the amount of insulin delivered. To do this.

However, in the conventional skin needle support as described above, dozens to hundreds of skin needles are fixed to the skin needle support exhibiting swelling behavior upon release of the insulin solvent, thereby making the skin needle 4 50-400 μm. It is difficult to process to have a diameter of, and the skin needle support is made of a material exhibiting swelling behavior in accordance with the release of the insulin solvent, thereby increasing the manufacturing cost. In addition, since the skin needle fixed dermal needle support is composed of an insulin solvent reservoir and one set, it has to be used only once and disposed of, so that there is a problem that the loss is large and the economic burden of the consumer is increased. In addition, the number of skin needles fixed on the skin needle support is tens or hundreds, and thousands of skin needles are required for faster insulin delivery, but the insulin delivered through the epidermal layer of the skin is small because the number of skin needles is small. Since the amount of the solvent is too small, diabetic patients have to attach the insulin patch for a long time, so that not only the pain caused by the skin needles, but also the behavior is inconvenient.

As a way to solve the above problems, the Korean Patent Application Nos. 93-21511, 21512 and 21513 by the present applicant in the thousands of skin needles are formed on the skin needle plate to have uniform equal intervals in all directions A pretreatment device has been disclosed, which means that thousands of skin scratches can be obtained by pressing and releasing the skin needle at a constant pressure without the need for a separate drive. However, in the above-described insulin patch skin needle plate, since thousands of skin needles should be arranged on a small skin needle plate, it is very difficult and difficult to arrange skin needles with current production technology. Not only was it inefficient and productive, but it was also rarely practical.

This invention is intended to solve the above problems, the purpose of this invention is to laminate a plurality of skin needles and intermediate materials in the state of the intermediate material between the cylindrical skin needle plate, both ends of the skin needle plate larger diameter than the intermediate material In order to provide a skin scratch forming device for drug administration to prevent the pain and redness due to the non-uniformity of the skin pretreatment depth by the skin needle plate at both ends.

A feature of the skin scratch forming apparatus for drug administration for achieving the above object is in the skin scratch forming apparatus for drug administration which causes a plurality of scratches on the skin to administer the drug to the skin;

Circular thin plate and a plurality of skin needles are formed at the end;

The circular plate is composed of a plurality of central axes assembled.

In this design, the intervals between the skin needles formed at the ends of the circular thin plate are formed at equal intervals, and it is preferable to assemble the skin needles of the skin needles of the immediately adjacent discs by shifting them.

Hereinafter, with reference to the accompanying drawings, preferred embodiments of the skin scratch forming device for drug administration according to the present invention will be described in detail.

2 to 5 are views shown to explain the skin needle assembly according to the present invention. Here, the skin needle disc 10 is formed on the outer circumferential surface of the circular plate material by dozens of hundreds of skin needles 12 by etching or pressing at the same interval, the shaft hole 14 through which the central axis 30 penetrates in the center thereof. Is formed, and a plurality of fixing holes 16 through which the fixing rods 32 are fixed are formed around the shaft hole 14.

Spacer member 20 is attached to the skin needle plate 10 is a circular plate material for separating the skin needle plate 10 to a predetermined width, the spacer member 20 is fixed to the shaft hole 14 and the skin needle plate 10 The same shaft hole 22 and fixing hole 24 as that of the hole 16 are formed, respectively, and may be formed integrally with the skin needle disc 10.

On both ends of the skin needle disc 10 and the spacer member 20, the fixing rods 32 are fixed through the fixing holes 16 and 24 of the skin needle disc 10 and the spacer member 20, The reinforcing member 34 is attached to the state in close contact, and the acupuncture disc 10 is rotatable in the shaft holes 14 and 22 of the skin needle disc 10 and the spacer 20. ) Is penetrated.

The bearing 36 is inserted in both ends in the central axis 30, and a handle (not shown) can be assembled to the bearing 36 to be used.

The skin needle assembly configured as described above is attached to the spacer member 20 to the skin needle disc 10, the shaft hole 14, 22 and the fixing hole 16, 24 to match the skin needle disc 10 Dozens of layers are stacked in the direction of the central axis of the assembly and then integrated by inserting the fixing rods 32 into the fixing holes 16 and 24, respectively, and assembling the central shaft 30 through the shaft holes 14 and 22. do. At this time, the central shaft 30 is fixed to the skin needle plate 10 is cocked. Therefore, the handles are assembled at both ends of the central axis 30 to perform skin pretreatment.

Referring to the skin scratch forming method with reference to the skin scratch forming hole as described above, pressing the skin needle 12 of the skin needle disc 10 to a position to form the skin scratch while holding the handle is pressed at a constant pressure Push in the state. When the handle is pushed, as the skin needle plate 10 is rotated, the skin needle 12 of the skin needle plate 10 on the outer circumferential surface of the skin is formed to have the necessary number of skin scratches at a constant depth, and the position where the skin scratches are formed. Attaching an insulin patch to the insulin will allow the medication to be easily administered through the skin.

However, as shown in FIG. 5, since the reinforcing member 34 is provided after the skin needle discs 10 at both ends, the skin needles have a deeper skin depth to be processed by the skin needles. It may be accompanied by redness or redness.

This problem can be solved by the second embodiment of the present invention shown in Figs. 6 and 7, which will be described.

6 and 7, the same reference numerals as those in FIGS. 1 to 5 denote the same parts, and thus detailed description thereof will be omitted.

As shown in FIGS. 6 and 7, the skin needle disc 10 and the spacer 20 are alternately attached, and reinforcing members 100 are attached to both ends of the skin needle disc 10. Here, the diameter of the reinforcing member 100 is made larger than the diameter of the spacer 20 is an intermediate material. Therefore, it is possible to prevent damage to the skin by the skin needle disc 10 on the outermost side when the skin scratches are formed. In other words, when the outermost skin needle disc 10 rolls on the skin, the depth of the scratches may be uniform because the reinforcing member 100 serves as a guide for the skin. Therefore, since the scratch formation depth by the end skin needle disc becomes uniform, not only the pain due to the nonuniformity of the processing depth as in the prior art but also the redness does not occur.

As described above, according to the skin scratch forming device for drug administration according to the second embodiment of the present invention, since the skin treatment depth by the skin needles at both ends is uniform, the phenomenon of increasing the treatment depth can be prevented, Therefore, there is no pain at all and redness does not occur.

However, the skin scratch forming device shown in the second embodiment may not penetrate deep into the skin because its tip is merely a triangular shape. Need to change

As described above, according to the skin scratch forming device for drug administration according to the present invention, since the depth of skin treatment by the skin needles at both ends is uniform, the phenomenon of increasing the treatment depth can be prevented, and thus there is no pain at all. Not only does redness occur, but a lot of scratches occur on the skin by improving the outer circumferential shape of the skin needle, and thus insulin can be easily administered to the human skin.

Claims (6)

Claims [1] A skin scratching device for administering a medicine, wherein the skin scratches a plurality of scratches to administer the medicine to the skin. Circular thin plate and a plurality of skin needles are formed at the end; A central axis in which a plurality of circular thin plates are assembled; Skin scratch forming device for drug administration to be a reinforcing member formed on both ends of the central axis. The method of claim 1, Skin scratch forming device for drug administration, wherein the reinforcing member is spaced apart from the immediately adjacent skin needle disc. The method of claim 2, The skin scratch forming device for drug administration, wherein the spacing between the reinforcing member and the skin needle disc is equally spaced from the space between the discs. The method of claim 1, Skin scratch forming port for drug administration configured so that the five circumferential surface of the reinforcing member approximately coincides with the skin needle tip. The method of claim 1, Skin scratch forming device for drug administration, the outer diameter of the reinforcing member is larger than the diameter of the circle consisting of the skin needle root. The method of claim 1, Skin scratch forming device for drug administration is further formed on the left and right of the central axis.