JPWO2025009503A1 - - Google Patents

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Publication number
JPWO2025009503A1
JPWO2025009503A1 JP2025515752A JP2025515752A JPWO2025009503A1 JP WO2025009503 A1 JPWO2025009503 A1 JP WO2025009503A1 JP 2025515752 A JP2025515752 A JP 2025515752A JP 2025515752 A JP2025515752 A JP 2025515752A JP WO2025009503 A1 JPWO2025009503 A1 JP WO2025009503A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2025515752A
Other languages
Japanese (ja)
Other versions
JP7723457B2 (ja
JPWO2025009503A5 (https=
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Publication of JPWO2025009503A1 publication Critical patent/JPWO2025009503A1/ja
Publication of JPWO2025009503A5 publication Critical patent/JPWO2025009503A5/ja
Application granted granted Critical
Publication of JP7723457B2 publication Critical patent/JP7723457B2/ja
Active legal-status Critical Current
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C40B40/08Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
JP2025515752A 2023-07-03 2024-07-01 細胞膜透過性を有するペプチドおよびそのスクリーニング方法 Active JP7723457B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2023109588 2023-07-03
JP2023109588 2023-07-03
PCT/JP2024/023780 WO2025009503A1 (ja) 2023-07-03 2024-07-01 細胞膜透過性を有するペプチドおよびそのスクリーニング方法

Publications (3)

Publication Number Publication Date
JPWO2025009503A1 true JPWO2025009503A1 (https=) 2025-01-09
JPWO2025009503A5 JPWO2025009503A5 (https=) 2025-06-10
JP7723457B2 JP7723457B2 (ja) 2025-08-14

Family

ID=94171533

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025515752A Active JP7723457B2 (ja) 2023-07-03 2024-07-01 細胞膜透過性を有するペプチドおよびそのスクリーニング方法

Country Status (2)

Country Link
JP (1) JP7723457B2 (https=)
WO (1) WO2025009503A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005013073A (ja) * 2003-06-25 2005-01-20 Mitsubishi Pharma Corp 輸送ポリペプチドのスクリーニング方法
WO2006041194A1 (ja) * 2004-10-15 2006-04-20 Japan Science And Technology Agency mRNA-ピューロマイシン-タンパク質連結体作製用リンカー
JP2009527251A (ja) * 2006-02-20 2009-07-30 エファ・ユニバーシティ・インダストリー・コラボレイション・ファウンデイション 細胞膜透過性ペプチド
JP2019528693A (ja) * 2016-09-21 2019-10-17 アマル セラピューティクス エスエー 癌を治療するための細胞透過性ペプチド、マルチエピトープ、及びtlrペプチドアゴニストを含む融合体
WO2022238530A1 (en) * 2021-05-12 2022-11-17 University Of Copenhagen Psd-95 inhibitors and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2548807C2 (ru) * 2009-05-20 2015-04-20 Торэй Индастриз, Инк. Пептиды, проникающие в клетку
US10736941B2 (en) * 2015-05-19 2020-08-11 National University Corporation Kumamoto University Cell membrane-permeating peptide
NL2016207B1 (en) * 2016-02-02 2017-08-21 Stichting Katholieke Univ Selective cell penetrating peptides.
EP3597223A1 (en) 2018-07-17 2020-01-22 Centre National De La Recherche Scientifique Peptides for use as cell-penetrating peptides
KR102588548B1 (ko) * 2019-07-16 2023-10-16 주식회사 젠센 자가면역질환 및 염증성질환 펩타이드 치료제
JP7578991B2 (ja) * 2019-08-28 2024-11-07 国立研究開発法人理化学研究所 細胞膜透過性ベシクル

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005013073A (ja) * 2003-06-25 2005-01-20 Mitsubishi Pharma Corp 輸送ポリペプチドのスクリーニング方法
WO2006041194A1 (ja) * 2004-10-15 2006-04-20 Japan Science And Technology Agency mRNA-ピューロマイシン-タンパク質連結体作製用リンカー
JP2009527251A (ja) * 2006-02-20 2009-07-30 エファ・ユニバーシティ・インダストリー・コラボレイション・ファウンデイション 細胞膜透過性ペプチド
JP2019528693A (ja) * 2016-09-21 2019-10-17 アマル セラピューティクス エスエー 癌を治療するための細胞透過性ペプチド、マルチエピトープ、及びtlrペプチドアゴニストを含む融合体
WO2022238530A1 (en) * 2021-05-12 2022-11-17 University Of Copenhagen Psd-95 inhibitors and uses thereof

Also Published As

Publication number Publication date
WO2025009503A1 (ja) 2025-01-09
JP7723457B2 (ja) 2025-08-14

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